J:Radiat Oncol

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT66504 Binding of Agt and Agtr1a 8 1 0.39 3.78 1.78
2 INT210952 Il1 Positive_regulation of Gene_expression of Icam1 1 1 0.01 0.86 0.37
3 INT210953 Binding of VEGFA and Csf2 1 1 0.00 0.47 0.3
4 INT202313 Gene_expression of PDGFB Positive_regulation of Positive_regulation of Pdgfrb 1 1 0.14 1 0.29
5 INT202314 Gene_expression of PDGFB Positive_regulation of Phosphorylation of Pdgfrb 1 1 0.14 1 0.29
6 INT297258 Binding of Agt and Agtr2 1 1 0.23 0.7 0.25
7 INT297257 Agtr1a Positive_regulation of Agtr2 1 1 0.27 0.59 0.22
8 INT202312 PDGFB Positive_regulation of Gene_expression of Col7a1 1 1 0.01 0.7 0.16
9 INT202311 PDGFB Positive_regulation of Gene_expression of Fn1 1 1 0.02 0.7 0.16
10 INT335259 Binding of GSTM1 and RA1 1 1 0.11 0.78 0.13
11 INT352297 Regulation of Binding of CD99 and VIM 1 1 0.19 1.07 0.06
12 INT352296 Binding of CD99 and VIM 1 1 0.16 1.06 0.06
13 INT352299 Regulation of Binding of BCL2 and VIM 1 1 0.10 1.07 0.06
14 INT352298 Binding of BCL2 and VIM 1 1 0.09 1.06 0.06
15 INT202310 Binding of PDGFB and Pdgfrb 1 1 0.11 0.39 0.04
16 INT192914 Binding of ESR1 and GOPC 2 1 0.02 0.61 0
17 INT192913 Binding of ESR1 and HAMP 1 1 0.02 0.72 0
18 INT192912 Binding of HAMP and MIER3 1 1 0.01 0.71 0
19 INT192915 Binding of ESR1 and MIER3 1 1 0.00 0.72 0
20 INT191837 Binding of SMUG1 and Airn 1 1 0.02 0.98 0
21 INT315194 Binding of SFRP1 and Slc10a1 1 8 0.02 8.85 0
22 INT315187 Binding of SFRP1 and COPD 1 4 0.01 4.47 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 11 3152 0.78 2515.62 929.82
2 INT3439 Localization of Abat 1 1017 0.78 112.39 727.06
3 INT9238 Gene_expression of IL6 11 1575 0.78 1135.66 424.22
4 INT5235 Negative_regulation of TNF 2 924 0.59 772.91 331.98
5 INT5059 Positive_regulation of TNF 5 1050 0.70 896.51 322.81
6 INT34869 Negative_regulation of PTGS2 1 778 0.59 366.76 319.85
7 INT5379 Gene_expression of Fos 5 656 0.78 255.5 292.54
8 INT9158 Gene_expression of Tnf 1 722 0.78 522.01 277.68
9 INT6852 Localization of TNF 1 883 0.81 705.95 270.84
10 INT10832 Gene_expression of IL8 9 1050 0.78 698.72 270
11 INT5972 Gene_expression of IL1B 7 948 0.78 510.91 263.97
12 INT68684 Gene_expression of VEGFA 5 2371 0.78 1742.52 259.2
13 INT16868 Gene_expression of Il6 3 807 0.78 499.48 256.57
14 INT6665 Gene_expression of FOS 1 520 0.77 165.31 217.66
15 INT6481 Binding of TNF 1 624 0.48 510.2 214.82
16 INT6482 Positive_regulation of Gene_expression of TNF 2 659 0.70 569.88 210
17 INT11313 Positive_regulation of Il6 4 526 0.70 331.27 201.59
18 INT94952 Positive_regulation of Mapk14 1 305 0.70 197.83 186.61
19 INT10194 Positive_regulation of IL6 3 702 0.70 600.62 183.38
20 INT120811 Gene_expression of Gopc 2 1174 0.59 428.49 150.55
21 INT9660 Regulation of TNF 1 363 0.62 312.94 139.99
22 INT5380 Positive_regulation of Gene_expression of Fos 3 243 0.70 105.65 131.05
23 INT64161 Positive_regulation of Prkca 1 213 0.70 85.06 129.91
24 INT9235 Negative_regulation of Gene_expression of TNF 1 346 0.59 252.98 118.61
25 INT50674 Gene_expression of PTGS2 2 459 0.78 253.33 118.51
26 INT60526 Gene_expression of IL10 1 449 0.78 292.71 107.84
27 INT18009 Positive_regulation of CRP 1 518 0.70 553.03 103.74
28 INT90091 Gene_expression of GOPC 4 967 0.67 366.22 103.6
29 INT10838 Positive_regulation of IL8 3 381 0.70 295.51 101.62
30 INT11381 Positive_regulation of IL1B 1 330 0.70 209.31 100.9
31 INT48408 Gene_expression of ICAM1 1 494 0.78 340.08 88.6
32 INT48406 Gene_expression of Icam1 4 277 0.78 238.28 81.71
33 INT68682 Positive_regulation of VEGFA 1 640 0.70 454.14 81.65
34 INT99070 Gene_expression of Mapk14 3 147 0.78 103.99 79.59
35 INT749 Gene_expression of HLA-B 1 341 0.75 224.12 77.37
36 INT1724 Negative_regulation of ACE 1 437 0.59 315.64 74.48
37 INT11380 Negative_regulation of IL1B 1 215 0.59 125.62 72.35
38 INT5969 Gene_expression of Il1a 11 221 0.75 96.31 71.38
39 INT58400 Negative_regulation of Tnf 1 182 0.59 129.97 71
40 INT79494 Positive_regulation of Gene_expression of VEGFA 1 577 0.70 442.94 69.73
41 INT6849 Localization of IL1B 1 229 0.81 112.56 69.63
42 INT19511 Localization of Il6 2 212 0.81 118.17 67.67
43 INT5374 Gene_expression of Esr1 1 412 0.77 263.89 67.34
44 INT822 Gene_expression of ESR1 5 529 0.78 302.16 63.64
45 INT11318 Gene_expression of Gtf3a 1 274 0.52 183.82 60.89
46 INT39153 Positive_regulation of PTGS2 1 182 0.70 96.16 60.6
47 INT17564 Gene_expression of Gpt 3 322 0.75 208.51 60.36
48 INT8528 Negative_regulation of Gene_expression of Fos 1 100 0.59 41.15 55.6
49 INT49993 Positive_regulation of Gene_expression of Il6 1 149 0.70 88.07 53.78
50 INT52264 Gene_expression of IK 2 180 0.77 90.87 51.87
51 INT9210 Regulation of IL6 1 166 0.62 125.61 49.95
52 INT4345 Gene_expression of Gtf3a 2 157 0.67 80.75 48.47
53 INT671 Positive_regulation of Cea 1 221 0.69 164.5 47.79
54 INT374 Positive_regulation of Ldha 3 212 0.70 107.08 47.43
55 INT3361 Positive_regulation of Esr1 1 273 0.69 208.53 44.81
56 INT80124 Negative_regulation of VEGFA 3 450 0.58 311.19 44.53
57 INT613 Gene_expression of Alb 1 268 0.78 149.84 42.78
58 INT157666 Positive_regulation of GOPC 1 335 0.60 120.19 42.75
59 INT13354 Transcription of TNF 2 108 0.72 85.81 42.32
60 INT11560 Positive_regulation of CASP3 1 236 0.70 184.33 39.38
61 INT68975 Gene_expression of Mmp9 1 111 0.78 79.57 38.55
62 INT55135 Positive_regulation of Gene_expression of PTGS2 1 137 0.70 80.32 38.46
63 INT385 Gene_expression of Agt 3 182 0.78 63.62 37.91
64 INT9082 Positive_regulation of ESR1 5 238 0.69 148.51 36.69
65 INT101992 Localization of VEGFA 1 413 0.81 258.23 36.15
66 INT51017 Positive_regulation of Icam1 1 113 0.70 81.16 35.55
67 INT60710 Gene_expression of Col7a1 1 217 0.78 113.2 35.2
68 INT6484 Binding of IL1B 1 122 0.47 75.84 35.07
69 INT1624 Gene_expression of Cea 4 212 0.76 180.44 34.21
70 INT7538 Negative_regulation of IL2 1 95 0.57 47.31 31.7
71 INT65960 Gene_expression of BCL2 1 352 0.78 312.03 30.73
72 INT1179 Negative_regulation of Ace 4 157 0.59 67.03 30.46
73 INT68973 Positive_regulation of Mmp9 1 89 0.52 58.56 30.04
74 INT86437 Binding of IL6 1 154 0.48 121.22 29.3
75 INT28361 Gene_expression of TP53 7 443 0.78 384.86 28.8
76 INT15610 Localization of GOPC 1 223 0.65 68.26 28.7
77 INT8097 Gene_expression of EGF 2 122 0.77 75.94 28.47
78 INT52801 Regulation of Gene_expression of Tnf 1 55 0.62 48.74 26.59
79 INT5378 Regulation of Gene_expression of Fos 1 47 0.60 14.47 26.41
80 INT20462 Binding of ESR1 2 210 0.44 102.7 26.34
81 INT11159 Gene_expression of EGFR 8 698 0.78 548.93 25.69
82 INT172458 Regulation of Gopc 1 155 0.53 62.57 24.86
83 INT22708 Gene_expression of MUC1 1 297 0.78 232.71 24.19
84 INT10835 Regulation of IL8 1 79 0.49 53.04 24.14
85 INT5131 Gene_expression of GNRH1 6 109 0.78 28.79 23.94
86 INT11746 Positive_regulation of Il1a 2 65 0.63 42.94 23.54
87 INT99069 Positive_regulation of Gene_expression of Mapk14 1 42 0.53 29.84 23.16
88 INT91891 Gene_expression of Kit 2 268 0.78 158.89 22.67
89 INT4369 Gene_expression of Ldha 1 157 0.76 88.12 22.45
90 INT48692 Binding of VEGFA 1 345 0.48 210.3 21.31
91 INT1876 Positive_regulation of HLA-B 1 82 0.69 52.16 21.08
92 INT73593 Gene_expression of BAX 2 173 0.76 147.81 20.94
93 INT170444 Binding of Gopc 1 172 0.39 45.05 20.71
94 INT52457 Gene_expression of ABCB1 1 129 0.78 38.68 19.88
95 INT76924 Positive_regulation of Slc17a5 2 71 0.70 41.21 19.31
96 INT10833 Regulation of Gene_expression of IL8 1 68 0.62 38.74 18.46
97 INT5967 Negative_regulation of Il1a 1 51 0.57 27.09 18.24
98 INT86673 Positive_regulation of Bcl2 1 77 0.70 57.74 17.37
99 INT1767 Positive_regulation of PROC 2 83 0.67 54.14 17
100 INT13510 Gene_expression of ERBB2 1 530 0.78 405.68 16.79
101 INT65856 Positive_regulation of TP53 4 138 0.67 112.65 16.71
102 INT17313 Positive_regulation of HSPG2 4 57 0.67 55.78 16.65
103 INT108588 Gene_expression of CASP3 1 126 0.78 84.49 16.2
104 INT170855 Negative_regulation of GOPC 3 188 0.38 70.92 15.41
105 INT1706 Negative_regulation of PCa 1 33 0.47 10.7 15.27
106 INT34904 Negative_regulation of Gtf3a 1 48 0.15 38.88 13.73
107 INT5207 Negative_regulation of Alms1 1 70 0.41 41.56 13.68
108 INT27739 Positive_regulation of EGF 1 49 0.70 28.31 13.68
109 INT69878 Positive_regulation of Gene_expression of Gtf3a 1 48 0.29 36.78 13.57
110 INT86383 Negative_regulation of EGFR 5 258 0.59 173.94 13.32
111 INT55255 Positive_regulation of Localization of Il6 2 48 0.69 24.88 12.76
112 INT60461 Positive_regulation of Gene_expression of Il1a 3 40 0.61 17.23 12.35
113 INT19527 Negative_regulation of Gene_expression of Il1a 1 26 0.51 15.4 11.58
114 INT19795 Positive_regulation of EGFR 1 161 0.70 103.69 11.55
115 INT68976 Positive_regulation of Gene_expression of Mmp9 1 34 0.42 28.21 11.28
116 INT51265 Phosphorylation of TNF 1 32 0.81 25.33 10.75
117 INT27651 Gene_expression of S100A12 1 45 0.76 52.25 10.51
118 INT56450 Negative_regulation of Gene_expression of Icam1 1 33 0.52 27.21 10.15
119 INT2036 Localization of EGF 1 42 0.77 21.5 9.74
120 INT70134 Negative_regulation of TXK 2 124 0.23 81.96 9.59
121 INT33220 Negative_regulation of ras 1 110 0.58 70.21 9.19
122 INT73497 Regulation of IL10 1 33 0.45 22.6 9.19
123 INT2139 Negative_regulation of Cea 1 55 0.43 43.59 9.14
124 INT68133 Localization of Fgf2 1 36 0.81 15.37 9.14
125 INT76860 Gene_expression of HSPG2 1 32 0.65 37.14 9.06
126 INT1168 Binding of PROC 1 62 0.38 44.15 9.04
127 INT158796 Positive_regulation of SMUG1 2 67 0.70 38.97 8.98
128 INT44378 Gene_expression of GSTM1 1 69 0.76 34.61 8.81
129 INT113845 Protein_catabolism of PARP1 1 54 0.88 43.86 8.77
130 INT47769 Phosphorylation of Fos 2 20 0.61 3.03 8.68
131 INT70896 Gene_expression of PDGFB 21 48 0.65 33.55 8.39
132 INT65959 Positive_regulation of Gene_expression of BCL2 3 75 0.70 77.3 8.27
133 INT113987 Localization of IK 1 29 0.23 16.73 8.25
134 INT6557 Gene_expression of Eno2 2 65 0.77 54.42 8.17
135 INT389 Gene_expression of Ace 1 21 0.67 10.31 8.1
136 INT15687 Regulation of ESR1 1 91 0.60 40.42 7.95
137 INT94082 Regulation of Gene_expression of IK 2 19 0.23 10.03 7.93
138 INT48404 Regulation of Gene_expression of Icam1 1 21 0.62 15.1 7.81
139 INT126583 Positive_regulation of PARP1 1 50 0.68 41.44 7.78
140 INT111607 Gene_expression of CDH1 2 103 0.75 90.45 7.77
141 INT38971 Positive_regulation of Gene_expression of Gtf3a 1 27 0.60 18.25 7.77
142 INT162393 Gene_expression of SMUG1 5 58 0.75 38.78 7.7
143 INT52937 Gene_expression of Cd68 1 37 0.67 31.33 7.54
144 INT57748 Positive_regulation of Gene_expression of TP53 1 85 0.69 79.55 7.49
145 INT102749 Positive_regulation of Positive_regulation of CASP3 1 32 0.67 26.07 6.93
146 INT170381 Transcription of Gopc 1 59 0.60 15.96 6.82
147 INT117299 Localization of S100b 1 19 0.78 1.58 6.8
148 INT72532 Regulation of Gene_expression of Il1a 1 13 0.54 4.91 6.71
149 INT8101 Binding of INCENP 2 42 0.31 16.2 6.68
150 INT51137 Negative_regulation of GSTM1 7 39 0.43 14.74 6.5
151 INT98837 Positive_regulation of Bax 1 72 0.61 63.14 6.41
152 INT69561 Positive_regulation of GSTM1 2 23 0.50 5.69 6.36
153 INT39758 Gene_expression of Fn1 1 57 0.65 34.38 6.02
154 INT112545 Phosphorylation of TP53 2 28 0.80 14.13 5.93
155 INT5762 Negative_regulation of Gene_expression of Agt 1 18 0.57 6.09 5.84
156 INT131944 Gene_expression of Mki67 1 30 0.53 6.58 5.63
157 INT141146 Gene_expression of Mmp13 1 18 0.38 8.61 5.54
158 INT80657 Gene_expression of SLC17A5 2 50 0.75 39.98 5.44
159 INT96778 Positive_regulation of Pdgfa 3 22 0.46 12.7 5.31
160 INT22597 Positive_regulation of TF 1 43 0.68 27.27 5.17
161 INT171033 Localization of SMPD1 1 15 0.16 11.92 5.16
162 INT89104 Binding of TGFB1 1 29 0.44 13.67 5.12
163 INT105393 Positive_regulation of Localization of VEGFA 1 66 0.70 45.45 4.9
164 INT17312 Binding of HSPG2 2 30 0.41 33.01 4.88
165 INT178754 Positive_regulation of Localization of GOPC 1 32 0.43 10.1 4.73
166 INT62684 Negative_regulation of TP53 1 66 0.58 66.09 4.62
167 INT68216 Binding of NF1 1 40 0.48 51.24 4.59
168 INT57749 Negative_regulation of Gene_expression of TP53 1 39 0.56 36.79 4.45
169 INT35765 Gene_expression of TXNRD1 1 47 0.56 9.16 4.43
170 INT74531 Regulation of PDGFB 1 14 0.26 7.57 4.38
171 INT5219 Negative_regulation of DBP 1 43 0.57 23.35 4.26
172 INT44578 Binding of Hbb 1 19 0.48 3.12 4.2
173 INT123752 Regulation of Bax 1 19 0.60 16.45 4
174 INT10992 Gene_expression of PARP1 2 32 0.76 22.22 3.74
175 INT70996 Positive_regulation of Positive_regulation of Icam1 1 8 0.60 6.02 3.74
176 INT174816 Binding of IL6R 1 14 0.09 11.26 3.63
177 INT124185 Negative_regulation of Kit 2 57 0.59 35.43 3.61
178 INT70897 Positive_regulation of Gene_expression of PDGFB 8 15 0.57 13.04 3.52
179 INT130646 Regulation of CXCL12 2 14 0.47 7.67 3.48
180 INT163832 Negative_regulation of Gene_expression of EGFR 1 50 0.59 39.71 3.45
181 INT70895 Localization of PDGFB 4 20 0.52 8.98 3.4
182 INT122051 Negative_regulation of ROM1 2 17 0.48 9.11 3.38
183 INT22375 Localization of PDGFA 1 21 0.75 15.46 3.25
184 INT57767 Gene_expression of HK1 2 17 0.30 9.72 3.22
185 INT70885 Gene_expression of Pdgfb 1 48 0.67 42.27 3.19
186 INT155091 Localization of PARP1 1 15 0.63 13.34 3.15
187 INT101083 Binding of Fgf2 1 14 0.42 4.12 3.14
188 INT117348 Regulation of EGFR 2 75 0.61 47.73 3.09
189 INT91173 Gene_expression of Pdgfrb 4 33 0.65 32.55 3.09
190 INT82168 Positive_regulation of S100b 1 20 0.68 9.72 3.08
191 INT114702 Gene_expression of Fgf1 1 34 0.74 17.39 2.96
192 INT74508 Gene_expression of Gypa 2 7 0.75 2.15 2.89
193 INT133144 Localization of Mtpn 1 18 0.24 7.88 2.77
194 INT121493 Gene_expression of XRCC1 1 55 0.65 73.43 2.76
195 INT1922 Positive_regulation of CEACAM7 1 32 0.70 33.31 2.72
196 INT11379 Positive_regulation of Negative_regulation of IL1B 1 9 0.49 7.2 2.64
197 INT74527 Positive_regulation of PDGFB 8 14 0.38 13.31 2.54
198 INT28865 Positive_regulation of Gene_expression of Cea 1 21 0.57 15.03 2.52
199 INT83295 Positive_regulation of Cd68 1 21 0.39 14.55 2.46
200 INT137908 Phosphorylation of Pdgfrb 3 14 0.81 8.44 2.45
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