J:Reprod Biol Endocrinol

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT182194 Binding of IL8 and CXCR2 10 1 0.56 7.14 4.16
2 INT180984 IRF6 Positive_regulation of Localization of IL8 7 1 0.11 2.13 3.47
3 INT208572 Binding of IL8 and CXCR1 6 1 0.33 5.2 3.08
4 INT175329 Binding of ICAM1 and ITGAL 14 2 0.18 10.06 2.81
5 INT252633 Binding of TNF and Tnfrsf1b 4 1 0.05 3.66 1.54
6 INT182125 Binding of CD14 and TLR4 7 1 0.25 3.78 1.03
7 INT285418 IRF6 Positive_regulation of Localization of IL6 3 1 0.05 0.66 0.93
8 INT225690 KNG1 Positive_regulation of TRPV1 1 1 0.42 0.7 0.83
9 INT225691 TRPV1 Positive_regulation of Localization of CALCA 1 1 0.18 0.7 0.83
10 INT286346 IRF6 Positive_regulation of IL8 3 2 0.03 0.88 0.8
11 INT142847 IRF6 Positive_regulation of IL6 5 1 0.07 1.09 0.73
12 INT104835 IRF6 Positive_regulation of IL10 4 2 0.32 0.91 0.69
13 INT257745 SAGE1 Positive_regulation of AXL 1 2 0.07 1.96 0.69
14 INT253935 Binding of PTPLA and Trpv1 1 1 0.14 1.25 0.65
15 INT45780 GNRH1 Positive_regulation of PLOD1 3 1 0.07 1.02 0.63
16 INT179850 Binding of Ecm1 and Il11 1 2 0.02 0 0.6
17 INT330491 Binding of Nka1 and SFTPA1 2 1 0.00 0 0.58
18 INT199976 EGF Regulation of ITGB3BP 1 2 0.02 0.77 0.57
19 INT175626 TIMP1 Positive_regulation of Gene_expression of MMP9 1 1 0.03 0.72 0.57
20 INT175627 TIMP1 Positive_regulation of MMP2 1 1 0.03 0.71 0.56
21 INT175623 TIMP1 Positive_regulation of MMP9 1 1 0.03 0.71 0.56
22 INT175323 Tlr4 Positive_regulation of Gene_expression of TLR2 1 1 0.02 0.31 0.56
23 INT286349 IRF6 Positive_regulation of Localization of IL10 1 1 0.03 1.22 0.55
24 INT177504 Gabrg1 Positive_regulation of PCNA 1 1 0.07 0.22 0.52
25 INT175326 SERPINH1 Regulation of Pnlip 1 1 0.00 0.53 0.49
26 INT286352 IL6 Positive_regulation of Gene_expression of IL8 2 1 0.24 1.32 0.48
27 INT252634 Binding of TNF and Tnfrsf1a 4 1 0.02 2.4 0.46
28 INT257738 PIK3CA Regulation of Localization of ACTN4 1 1 0.16 1.03 0.39
29 INT208571 CCL21 Positive_regulation of Gene_expression of CCL16 1 1 0.51 0.63 0.38
30 INT179851 Il11 Positive_regulation of Mmp2 1 1 0.04 0 0.38
31 INT199974 ESR1 Negative_regulation of Gene_expression of ITGB3BP 1 2 0.05 0.47 0.38
32 INT197591 Esr1 Regulation of Pgr 1 3 0.04 0 0.38
33 INT173704 Binding of PCOS1 and Edn1 1 1 0.01 0.99 0.37
34 INT179839 Il11 Negative_regulation of Mmp1a 1 1 0.03 0 0.37
35 INT286351 IL8 Positive_regulation of Gene_expression of IRF6 1 1 0.03 0.71 0.36
36 INT286347 IL8 Positive_regulation of Gene_expression of IL6 1 1 0.11 0.7 0.36
37 INT286350 IL6 Positive_regulation of Gene_expression of IRF6 1 1 0.04 0.71 0.36
38 INT257741 HRAS Negative_regulation of PTEN 1 1 0.15 1.06 0.35
39 INT179845 Il11 Positive_regulation of Negative_regulation of Timp1 1 1 0.14 0 0.35
40 INT257737 Positive_regulation of HRAS Negative_regulation of PTEN 1 1 0.17 1.07 0.35
41 INT175319 Negative_regulation of Nos2 Negative_regulation of Positive_regulation of Pnlip 1 1 0.01 0.83 0.34
42 INT177426 Izumo1 Positive_regulation of Positive_regulation of Fig4 1 1 0.16 0.59 0.34
43 INT257746 SHC1 Positive_regulation of Positive_regulation of PIK3CA 1 1 0.26 1.04 0.34
44 INT304320 Binding of Ptger2 and Ptger4 2 1 0.26 0.06 0.33
45 INT222721 Binding of HTR1A and Pdpk1 1 1 0.00 0.35 0.33
46 INT292014 Efs Regulation of Localization of Prl 1 1 0.26 0 0.33
47 INT175330 IL6 Positive_regulation of Gene_expression of CYP19A1 1 1 0.01 0.97 0.32
48 INT257743 Binding of PIK3CA and SHC1 1 1 0.21 1.03 0.31
49 INT194358 Binding of Ddt and Scgb1d2 1 1 0.01 0 0.31
50 INT187603 Binding of Ptgis and Ppara 1 1 0.00 0.26 0.31
51 INT257735 GAS6 Positive_regulation of Gene_expression of SAGE1 1 1 0.04 0.98 0.31
52 INT257739 SAGE1 Positive_regulation of DDR1 1 1 0.00 0.91 0.31
53 INT188288 Ghrl Regulation of Gene_expression of Pou1f1 1 2 0.07 0 0.3
54 INT179844 Nid1 Regulation of Negative_regulation of Il11 1 1 0.19 0 0.29
55 INT179842 Sparc Regulation of Negative_regulation of Il11 1 1 0.15 0 0.29
56 INT179838 Col3a1 Regulation of Negative_regulation of Il11 1 1 0.21 0 0.29
57 INT257744 Binding of PIK3R2 and SHC1 1 1 0.08 0.96 0.28
58 INT199978 ESR1 Regulation of ITGB3BP 1 1 0.03 0.39 0.28
59 INT191718 Binding of FLT1 and VEGFA 35 2 0.50 12.18 0.27
60 INT71904 Binding of ESR1 and PGR 6 1 0.34 3.79 0.27
61 INT257740 SAGE1 Positive_regulation of Gene_expression of AXL 1 1 0.07 0.72 0.27
62 INT177491 Binding of Gad2 and Slc32a1 1 2 0.06 0.06 0.25
63 INT175321 IL6 Positive_regulation of Localization of Oxt 1 1 0.01 0.7 0.25
64 INT175322 Oxt Positive_regulation of Gene_expression of PTGER2 1 1 0.00 0.09 0.25
65 INT177502 Binding of Gabrg1 and Gad2 1 1 0.14 0.07 0.25
66 INT199970 CYP19A1 Positive_regulation of Gene_expression of ESR1 1 1 0.06 0.72 0.25
67 INT278581 Tacr2 Positive_regulation of Tacr1 1 1 0.55 0 0.24
68 INT199971 IL6 Positive_regulation of ESR1 1 1 0.08 0.84 0.24
69 INT278582 Atp6v1e1 Positive_regulation of Positive_regulation of Tac1 1 1 0.15 0.13 0.24
70 INT278578 Tacr3 Positive_regulation of Tacr1 1 1 0.55 0 0.24
71 INT278570 Nka1 Positive_regulation of Tacr1 1 1 0.06 0 0.24
72 INT197590 Esr2 Positive_regulation of Negative_regulation of Pgr 1 1 0.16 0 0.24
73 INT175324 Hsp90b1 Positive_regulation of TLR2 1 1 0.00 0.65 0.23
74 INT234755 IL10 Positive_regulation of IFN1@ 1 1 0.08 0.68 0.23
75 INT177425 Binding of Fig4 and Izumo1 1 1 0.12 0.59 0.23
76 INT175317 Hsp90b1 Positive_regulation of Tlr4 1 1 0.02 0.66 0.23
77 INT123660 F2R Positive_regulation of PAR1 2 1 0.10 1.96 0.22
78 INT281896 KNG1 Regulation of Binding of KNG1 and NOS3 1 1 0.02 0.17 0.22
79 INT288582 Binding of Cav1 and Kcnma1 1 15 0.11 0 0.22
80 INT180670 Cpd Regulation of Protein_catabolism of Ecm1 1 1 0.04 0.14 0.22
81 INT281901 Binding of KNG1 and NOS3 1 1 0.05 0.17 0.22
82 INT201868 PASK Regulation of POU5F2 1 1 0.00 0.12 0.21
83 INT175320 Tlr4 Positive_regulation of Gene_expression of Mmp9 1 1 0.01 0.54 0.21
84 INT281903 BDKRB1 Positive_regulation of KNG1 1 1 0.03 0.32 0.21
85 INT286348 IL8 Positive_regulation of IL10 1 1 0.08 0.18 0.19
86 INT211674 Gtf3a Regulation of Positive_regulation of Igj 1 1 0.01 0.8 0.19
87 INT179941 Binding of Prl and Vip 1 1 0.09 0 0.19
88 INT197618 Binding of Esr1 and Ppt1 1 1 0.01 0 0.18
89 INT179841 Il11 Regulation of Positive_regulation of Akt1 1 1 0.08 0.07 0.17
90 INT179837 Il11 Regulation of Positive_regulation of Rps6kb2 1 1 0.06 0.07 0.17
91 INT339252 Positive_regulation of GNRH1 Positive_regulation of Localization of SCG5 1 1 0.51 0 0.17
92 INT179846 Il11 Regulation of Positive_regulation of Rps6 1 1 0.04 0.07 0.17
93 INT179849 Il11 Regulation of Positive_regulation of Pdpk1 1 1 0.05 0.07 0.17
94 INT246414 TLR4 Regulation of Gene_expression of TLR3 1 1 0.35 1.16 0.17
95 INT201865 Binding of PGR and NCOA1 1 1 0.03 0 0.17
96 INT175328 FASLG Positive_regulation of FAS 1 1 0.01 0.9 0.17
97 INT273251 Binding of IL6 and IL12A 1 1 0.00 1.15 0.16
98 INT278576 Olfr714 Regulation of Gene_expression of Tacr3 1 3 0.10 0 0.15
99 INT191001 F3 Positive_regulation of F2 1 1 0.00 0.62 0.14
100 INT180671 Binding of Plat and Regulation of Serpine1 1 1 0.16 0.06 0.14
101 INT201867 Binding of PGR and PASK 1 1 0.02 0.23 0.14
102 INT211860 PLOD1 Regulation of AGRP 1 1 0.07 0.15 0.14
103 INT194360 SNRPD1 Negative_regulation of Dbh 1 1 0.00 0 0.14
104 INT102885 Binding of ANG and ACE 2 1 0.17 0.37 0.13
105 INT330486 MSR1 Negative_regulation of TAC1 1 1 0.01 0.23 0.13
106 INT278583 Ppt1 Negative_regulation of Gene_expression of Atp6v1e1 1 1 0.05 0 0.13
107 INT281911 Binding of ANG and MAS1 1 1 0.05 0.39 0.13
108 INT330485 MSR1 Negative_regulation of TACR1 1 1 0.01 0.23 0.13
109 INT197072 Binding of Slc3a1 and Atr 1 1 0.07 0.32 0.13
110 INT339254 GNRHR Regulation of GNRH1 1 1 0.24 0.23 0.12
111 INT290565 Binding of Rare1 and Rorb 1 1 0.00 0.32 0.12
112 INT186243 IL36RN Positive_regulation of B4GALNT1 1 1 0.00 0.43 0.12
113 INT290563 Binding of Rxrg and Rorb 1 1 0.00 0.2 0.12
114 INT339251 KISS1R Regulation of GNRH1 1 1 0.28 0.23 0.12
115 INT284891 FSHR Positive_regulation of Gene_expression of PLOD1 2 1 0.03 1.32 0.11
116 INT177490 Binding of Gad1 and Gad2 1 1 0.10 0.19 0.11
117 INT65676 Binding of CGA and PLOD1 3 1 0.23 1.68 0.1
118 INT186240 Binding of AGRP and SCN5A 2 1 0.13 1.19 0.1
119 INT281905 Binding of AGTR2 and NOS3 1 1 0.08 0.37 0.1
120 INT186246 Binding of CAT and SCN5A 1 1 0.03 0.47 0.1
121 INT186242 Binding of ALB and SCN5A 1 1 0.04 0.36 0.1
122 INT281912 Binding of AGTR2 and ANG 1 1 0.13 0.37 0.1
123 INT186245 Binding of AGRP and CAT 1 1 0.02 0.53 0.1
124 INT281898 Binding of ANG and ACE Positive_regulation of KNG1 1 1 0.03 0.37 0.1
125 INT281899 Binding of ANG and NOS3 1 1 0.12 0.37 0.1
126 INT272389 Bcar1 Negative_regulation of Gene_expression of Trpv6 1 1 0.01 0 0.1
127 INT186244 Binding of AGRP and ALB 1 1 0.03 0.53 0.1
128 INT197914 Dlst Positive_regulation of Positive_regulation of S100g 1 1 0.06 0 0.1
129 INT186539 Crh Regulation of Hpse 1 1 0.09 0.52 0.1
130 INT278573 Atp6v1e1 Regulation of Gene_expression of Tacr3 1 2 0.17 0.07 0.09
131 INT175325 Binding of TLR2 and Tlr6 1 1 0.00 0.39 0.09
132 INT175327 Binding of TLR2 and Tlr1 1 1 0.00 0.39 0.09
133 INT214752 EDNRA Positive_regulation of PLCB1 1 1 0.02 0 0.08
134 INT186540 Binding of Cort and Hpse 1 1 0.05 0.92 0.08
135 INT188291 Ghrl Regulation of Localization of LH 1 1 0.03 0 0.08
136 INT179847 Binding of Ecm1 and Sparc 1 2 0.04 0 0.08
137 INT199973 ESR1 Negative_regulation of EEF1B2P2 1 1 0.01 0.46 0.08
138 INT278580 Olfr714 Regulation of Atp6v1e1 1 1 0.03 0 0.08
139 INT205537 ATP8A2 Negative_regulation of Negative_regulation of RHOXF2 1 1 0.01 0 0.07
140 INT281900 Positive_regulation of Binding of AGT and AGTR1 1 1 0.12 0.16 0.07
141 INT272388 Esr1 Regulation of Transcription of Trpv6 1 2 0.03 0.13 0.06
142 INT187671 CGA Negative_regulation of Gene_expression of GNRH1 1 1 0.01 0 0.06
143 INT191002 F2 Positive_regulation of Gene_expression of IL8 1 1 0.02 0.46 0.06
144 INT330487 Binding of MME and HPSE 1 1 0.35 0 0.06
145 INT197594 Esr1 Regulation of Esr2 1 1 0.04 0 0.06
146 INT187845 Binding of ESR1 and Esr2 1 1 0.01 0.17 0.06
147 INT281909 Binding of AGT and AGTR1 1 1 0.09 0.16 0.06
148 INT197592 Esr2 Regulation of Esr1 1 1 0.04 0 0.06
149 INT197617 Binding of S100a6 and Rb1 1 2 0.03 0 0.06
150 INT201866 Binding of AR and PGR 1 1 0.07 0.34 0.06
151 INT197586 Esr2 Regulation of Pgr 1 1 0.09 0 0.06
152 INT179852 Binding of PTPRC and Ecm1 1 1 0.00 0 0.05
153 INT281906 BDKRB2 Positive_regulation of ANG 1 1 0.11 0.51 0.05
154 INT180668 Edn1 Positive_regulation of Gene_expression of Col1a1 1 1 0.02 0 0.05
155 INT187602 Binding of Ppara and Rxrb 1 1 0.00 0 0.05
156 INT330490 Binding of TAC3 and Nka1 1 1 0.02 0 0.05
157 INT175625 PAR1 Regulation of Gene_expression of MMP9 1 1 0.02 1.25 0.05
158 INT246413 TLR4 Regulation of TLR3 1 1 0.28 0.81 0.05
159 INT180667 Edn1 Regulation of Ecm1 1 1 0.04 0 0.05
160 INT175631 F2RL1 Positive_regulation of Positive_regulation of MMP1 1 1 0.08 0.69 0.04
161 INT175083 TAF6L Regulation of Gene_expression of PENK 1 1 0.00 0.05 0.04
162 INT179836 Il11 Regulation of Gene_expression of Ecm1 1 1 0.05 0 0.04
163 INT288595 Binding of CYTIP and Kcnma1 1 2 0.00 0 0.04
164 INT197917 Binding of ESR1 and Sh2b2 1 1 0.01 0 0.04
165 INT268652 Binding of CLDN4 and LIF 1 3 0.35 0.44 0.04
166 INT207997 Bel Regulation of Gene_expression of Plg 1 1 0.00 0 0.04
167 INT339253 KISS1 Regulation of Localization of GNRH1 1 1 0.25 0.24 0.04
168 INT179840 Binding of Col3a1 and Sparc 1 1 0.25 0 0.04
169 INT175629 PAR1 Positive_regulation of Positive_regulation of MMP1 1 1 0.21 0.69 0.04
170 INT187732 Binding of CYP19A1 and Cyp11a1 1 1 0.01 0.68 0.04
171 INT278579 Esr1 Positive_regulation of Negative_regulation of Tac2 1 1 0.47 0.25 0.03
172 INT261727 TNF Regulation of COL5A2 1 1 0.05 0.21 0.03
173 INT261728 PSMB6 Negative_regulation of Transcription of F2R 1 1 0.01 0.17 0.03
174 INT197616 Ppt1 Negative_regulation of ge 1 1 0.00 0.05 0.03
175 INT185651 GOPC Positive_regulation of AR 1 1 0.03 0.06 0.03
176 INT261731 PSMB6 Regulation of COL5A2 1 1 0.00 0.21 0.03
177 INT278572 Atp6v1e1 Negative_regulation of Gene_expression of Tacr3 1 2 0.22 0 0.03
178 INT197587 Ppt1 Positive_regulation of Rb1 1 1 0.18 0 0.03
179 INT175628 F2R Positive_regulation of F2RL1 1 1 0.04 1.46 0.03
180 INT186249 Binding of ROS1 and SCN5A 1 1 0.09 0.73 0.03
181 INT197593 Dlat Positive_regulation of Rb1 1 1 0.04 0 0.03
182 INT339249 KISS1 Positive_regulation of GNRH1 1 1 0.64 0.21 0.03
183 INT261733 F2 Regulation of COL5A2 1 1 0.03 0.21 0.03
184 INT187676 Binding of CYP19A1 and SHBG 1 1 0.01 0.63 0.03
185 INT206705 Negative_regulation of Binding of FLT1 and VEGFA 3 1 0.11 1.9 0
186 INT198111 Binding of Esr1 and Esr2 1 1 0.05 0 0
187 INT281908 VEGFA Positive_regulation of NOS3 1 2 0.14 0.14 0
188 INT197903 Dlst Positive_regulation of S100g 1 1 0.04 0 0
189 INT211671 Gtf3a Regulation of Tnni2 1 1 0.01 0.33 0
190 INT187621 Gnrh1 Regulation of Gene_expression of Pparg 1 1 0.00 0.09 0
191 INT261729 COL5A2 Regulation of Gene_expression of F2R 1 2 0.18 0 0
192 INT187672 Binding of DBT and SCN5A 1 1 0.00 0.2 0
193 INT197909 Des Positive_regulation of S100g 1 1 0.03 0 0
194 INT268651 NUPL2 Positive_regulation of Gene_expression of LIF 1 1 0.66 0.07 0
195 INT187677 Negative_regulation of FSHR Positive_regulation of DBT 1 1 0.03 0 0
196 INT201800 OLFM1 Regulation of EHF 1 1 0.05 0 0
197 INT186248 NR5A1 Positive_regulation of Transcription of STAR 1 1 0.01 0.21 0
198 INT188289 Ghrl Negative_regulation of Gnrh1 1 1 0.08 0.17 0
199 INT188295 Binding of KITLG and Ghrl 1 1 0.02 0.09 0
200 INT288584 Cav1 Regulation of Gene_expression of Kcnma1 1 1 0.14 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT158 Localization of Prl 54 2431 0.81 378.96 952.2
2 INT6483 Gene_expression of TNF 6 3152 0.78 2515.62 929.82
3 INT58061 Gene_expression of Trpv1 34 1117 0.78 451.54 637.59
4 INT155 Positive_regulation of Prl 10 1233 0.70 317.93 457.82
5 INT1045 Localization of LH 35 1211 0.81 87.04 456.25
6 INT443 Localization of POMC 14 1020 0.81 284.52 443.17
7 INT9238 Gene_expression of IL6 15 1575 0.78 1135.66 424.22
8 INT64202 Positive_regulation of Trpv1 7 643 0.70 249.66 397.42
9 INT467 Gene_expression of POMC 5 1048 0.78 332.8 394.16
10 INT76660 Gene_expression of Trpv1 7 691 0.78 329.46 386.42
11 INT18357 Gene_expression of TRPV1 8 825 0.78 307.11 382.81
12 INT157 Positive_regulation of Localization of Prl 18 790 0.70 104.54 374.78
13 INT439 Localization of Gnrh1 32 976 0.81 100.96 363.25
14 INT720 Positive_regulation of POMC 5 807 0.70 237.37 353.83
15 INT876 Localization of Gh1 3 843 0.80 67.75 340.82
16 INT5059 Positive_regulation of TNF 5 1050 0.70 896.51 322.81
17 INT162 Regulation of Prl 6 794 0.62 165.01 322.24
18 INT5979 Gene_expression of Oprd1 1 428 0.78 75.64 320.32
19 INT5680 Gene_expression of Ngf 23 530 0.78 264.29 310.56
20 INT46460 Gene_expression of NAV1 22 288 0.78 135.51 305.75
21 INT9131 Positive_regulation of Prkcg 8 431 0.70 130.8 302.41
22 INT161 Regulation of Localization of Prl 18 615 0.62 65.37 298.66
23 INT1352 Localization of Acot1 1 728 0.80 73.01 296.01
24 INT11624 Gene_expression of OPRM1 1 445 0.78 72.36 294.36
25 INT9158 Gene_expression of Tnf 4 722 0.78 522.01 277.68
26 INT9381 Positive_regulation of TRPV1 7 523 0.70 187.4 276.05
27 INT49750 Negative_regulation of CPOX 17 735 0.58 360.06 274.19
28 INT6852 Localization of TNF 1 883 0.81 705.95 270.84
29 INT10832 Gene_expression of IL8 20 1050 0.78 698.72 270
30 INT5972 Gene_expression of IL1B 5 948 0.78 510.91 263.97
31 INT68684 Gene_expression of VEGFA 24 2371 0.78 1742.52 259.2
32 INT738 Regulation of POMC 5 459 0.62 111.19 243.74
33 INT11377 Positive_regulation of Ngf 7 331 0.70 206.5 238
34 INT1562 Localization of Crh 1 499 0.81 126.74 236.68
35 INT626 Localization of CALCA 1 289 0.81 125.39 221.15
36 INT6481 Binding of TNF 2 624 0.48 510.2 214.82
37 INT767 Localization of Gnrhr 1 565 0.80 106.68 214.57
38 INT22548 Positive_regulation of Casp3 5 483 0.70 258.78 213.07
39 INT9132 Negative_regulation of Prkcg 6 279 0.59 88.05 203.47
40 INT50670 Gene_expression of CPOX 3 763 0.76 442.13 195.02
41 INT156 Negative_regulation of Prl 2 542 0.59 131.97 192.24
42 INT528 Gene_expression of Prl 10 693 0.78 217.18 192.2
43 INT2085 Positive_regulation of LH 15 441 0.70 60.15 191.02
44 INT6354 Localization of Gabrg1 6 321 0.74 41.41 186.74
45 INT1652 Regulation of Pomc 1 387 0.62 61.01 186.51
46 INT10194 Positive_regulation of IL6 12 702 0.70 600.62 183.38
47 INT4803 Transcription of Penk 1 435 0.72 59.09 182.4
48 INT159 Negative_regulation of Localization of Prl 2 416 0.59 55.34 171.8
49 INT438 Gene_expression of Crh 1 376 0.78 159.11 169.17
50 INT739 Negative_regulation of POMC 3 358 0.59 102.28 166.77
51 INT55879 Gene_expression of CCL2 5 421 0.78 240.74 166.02
52 INT1114 Localization of Ins1 1 748 0.80 192.95 165.48
53 INT5127 Localization of Lhb 44 488 0.80 50.48 162.66
54 INT66280 Gene_expression of Nos2 1 534 0.78 330.78 157.07
55 INT1044 Negative_regulation of Localization of LH 5 358 0.59 25.95 151.31
56 INT120811 Gene_expression of Gopc 9 1174 0.59 428.49 150.55
57 INT13353 Positive_regulation of Tnf 1 332 0.70 248.75 148.1
58 INT812 Localization of INS 2 1026 0.81 515.6 145.31
59 INT425 Localization of PRL 1 455 0.81 189.64 144.8
60 INT2379 Positive_regulation of Localization of LH 15 349 0.70 27.86 144.53
61 INT60694 Gene_expression of Il10 8 567 0.78 369.48 143.69
62 INT9660 Regulation of TNF 1 363 0.62 312.94 139.99
63 INT14843 Gene_expression of Gabrg1 16 301 0.77 62.63 139.16
64 INT2867 Gene_expression of CALCA 2 247 0.78 78.78 138.47
65 INT1047 Negative_regulation of LH 5 314 0.59 53.71 135.89
66 INT60126 Regulation of Trpv1 5 186 0.62 85.53 133.4
67 INT5497 Positive_regulation of Crh 1 299 0.70 125.54 131.14
68 INT416 Regulation of LH 6 253 0.62 31.48 125.55
69 INT6323 Positive_regulation of Gabrg1 2 213 0.70 45.08 124.34
70 INT2106 Regulation of Localization of LH 7 279 0.62 22.37 122.77
71 INT6128 Positive_regulation of Localization of POMC 4 256 0.70 68.77 121.64
72 INT7533 Gene_expression of Tlr4 6 720 0.78 343.22 121.57
73 INT14151 Gene_expression of Casp3 1 311 0.78 140.26 120.68
74 INT218 Positive_regulation of Th 4 245 0.70 40.5 120.1
75 INT64201 Negative_regulation of Trpv1 2 203 0.59 79.18 119.75
76 INT50674 Gene_expression of PTGS2 2 459 0.78 253.33 118.51
77 INT7395 Localization of GNRH1 17 399 0.81 62.88 117.68
78 INT12339 Localization of IL8 14 437 0.81 251.87 117.39
79 INT62124 Gene_expression of NOS1 15 444 0.78 218.08 114.85
80 INT48593 Positive_regulation of NOS1 10 420 0.68 226.15 114.71
81 INT1793 Localization of CGA 12 379 0.81 67.38 114.69
82 INT20374 Gene_expression of Il4 7 515 0.76 306.15 114.12
83 INT170025 Gene_expression of Fig4 11 588 0.67 183.27 113.32
84 INT90 Localization of Gast 1 400 0.81 137.67 113
85 INT11051 Positive_regulation of Gene_expression of IL6 2 415 0.69 319.21 109.3
86 INT47243 Gene_expression of Prkcg 22 195 0.78 58.05 108.44
87 INT60526 Gene_expression of IL10 8 449 0.78 292.71 107.84
88 INT3038 Gene_expression of INS 21 1583 0.78 1174.16 107.01
89 INT9012 Localization of Vip 3 283 0.81 31.71 106.16
90 INT12082 Localization of IL6 11 365 0.81 241.78 105.78
91 INT12569 Localization of Oprd1 2 94 0.81 23.81 104.56
92 INT915 Positive_regulation of PRL 17 342 0.70 141.96 104.31
93 INT69440 Gene_expression of ROS1 53 752 0.78 477.64 103.83
94 INT90091 Gene_expression of GOPC 26 967 0.67 366.22 103.6
95 INT4742 Gene_expression of Tac1 8 177 0.78 69.99 102.66
96 INT89054 Positive_regulation of Gene_expression of Trpv1 1 156 0.70 90.78 102.03
97 INT10838 Positive_regulation of IL8 16 381 0.70 295.51 101.62
98 INT82878 Gene_expression of Ccl2 2 201 0.78 164.95 101.35
99 INT2159 Regulation of Localization of Gnrh1 2 200 0.62 13.28 99.07
100 INT4822 Localization of Ca2 1 417 0.80 99.57 96.45
101 INT1760 Gene_expression of PTGER2 4 524 0.57 226.94 96.4
102 INT11587 Gene_expression of CSF2 1 645 0.78 544.38 93.89
103 INT69764 Positive_regulation of Cnr1 4 126 0.70 67.8 91.49
104 INT77435 Positive_regulation of Nos2 1 343 0.70 208.49 91.43
105 INT38731 Localization of Trpv1 1 138 0.81 52.73 90.49
106 INT48767 Negative_regulation of NOS1 4 312 0.59 154.25 90.32
107 INT74376 Gene_expression of Cnr1 25 173 0.78 73.43 89.7
108 INT71789 Positive_regulation of MAPK1 1 396 0.70 234.44 89.27
109 INT48408 Gene_expression of ICAM1 17 494 0.78 340.08 88.6
110 INT4798 Gene_expression of Nts 1 169 0.77 29.56 86.04
111 INT2149 Positive_regulation of Oxt 6 181 0.70 24.8 85.43
112 INT4830 Binding of Trpv1 6 158 0.48 45.11 84.2
113 INT4289 Positive_regulation of Localization of Gnrh1 6 202 0.70 12.3 84.01
114 INT16254 Positive_regulation of Gene_expression of Ngf 8 144 0.70 80.61 82.08
115 INT68682 Positive_regulation of VEGFA 13 640 0.70 454.14 81.65
116 INT10534 Positive_regulation of Trib3 3 209 0.60 78.75 81.48
117 INT2289 Gene_expression of PENK 1 203 0.78 55.62 79.49
118 INT2893 Localization of Oxt 1 219 0.80 28.96 79.43
119 INT920 Localization of PLOD1 18 223 0.81 42.25 78.7
120 INT2431 Positive_regulation of Mpo 1 275 0.70 211.99 78.47
121 INT17546 Negative_regulation of Ngf 5 135 0.59 60.28 77.19
122 INT12001 Regulation of Ngf 1 97 0.62 54.64 76.25
123 INT3657 Gene_expression of Ins1 4 514 0.78 321.69 75.76
124 INT25363 Negative_regulation of Trpv1 2 144 0.59 64.78 75.7
125 INT15769 Gene_expression of Il1b 2 146 0.78 114.51 75.35
126 INT98621 Regulation of Trpv1 1 121 0.62 79.24 75.23
127 INT5056 Gene_expression of IFNG 1 216 0.78 137.52 74.57
128 INT12536 Localization of Prkcg 2 101 0.80 36.37 73.81
129 INT56298 Gene_expression of IL4 3 306 0.78 182.18 72.92
130 INT3034 Localization of Ngf 2 126 0.81 50.81 72.84
131 INT39565 Gene_expression of Ptger2 30 424 0.75 229.28 72.68
132 INT12720 Positive_regulation of Il1 2 246 0.70 195.97 72.05
133 INT5128 Positive_regulation of Lhb 22 232 0.69 44.23 71.26
134 INT2055 Regulation of Gnrh1 2 185 0.62 23.65 71.26
135 INT5993 Positive_regulation of Nts 1 122 0.70 26.82 70.45
136 INT10837 Positive_regulation of Gene_expression of IL8 5 294 0.70 190.08 70.34
137 INT171145 Positive_regulation of Fig4 10 274 0.59 93.55 69.81
138 INT79494 Positive_regulation of Gene_expression of VEGFA 5 577 0.70 442.94 69.73
139 INT170332 Gene_expression of IFN1@ 16 477 0.75 275.21 69.65
140 INT451 Regulation of Oxt 2 142 0.62 22.07 69.42
141 INT87686 Positive_regulation of Gene_expression of Trpv1 1 101 0.70 72.41 69.15
142 INT2123 Positive_regulation of Gnrh1 2 209 0.70 24.2 68.97
143 INT8357 Gene_expression of KNG1 2 153 0.75 77.26 68.66
144 INT7344 Gene_expression of TAC1 6 132 0.75 35.48 68.26
145 INT39777 Regulation of Prkcg 6 90 0.62 31.52 68.17
146 INT5374 Gene_expression of Esr1 20 412 0.77 263.89 67.34
147 INT1046 Gene_expression of LH 9 180 0.77 29.75 66.87
148 INT9489 Gene_expression of SFTPA1 2 112 0.66 55.38 66.45
149 INT253 Regulation of PRL 2 184 0.62 47.27 65.79
150 INT5941 Gene_expression of Oxt 5 164 0.76 22.63 65.47
151 INT13286 Gene_expression of Ca2 4 317 0.67 71.58 65.01
152 INT1599 Positive_regulation of ADCY1 2 146 0.67 30.05 64.9
153 INT822 Gene_expression of ESR1 38 529 0.78 302.16 63.64
154 INT67614 Positive_regulation of PPARA 2 438 0.68 293.28 63.61
155 INT2056 Negative_regulation of Gnrh1 1 175 0.59 33.43 63.32
156 INT6894 Gene_expression of CNR1 2 168 0.78 74.07 62.84
157 INT17401 Gene_expression of IGF1 3 475 0.78 232.18 62.07
158 INT6761 Binding of CALCA 1 100 0.48 26.71 62.05
159 INT67981 Positive_regulation of CCL2 2 165 0.70 136.84 61.85
160 INT39153 Positive_regulation of PTGS2 1 182 0.70 96.16 60.6
161 INT2761 Regulation of Gabrg1 1 119 0.61 18.8 60.52
162 INT9196 Gene_expression of PTGS1 2 215 0.77 96.99 60.5
163 INT103924 Positive_regulation of Akt1 2 359 0.69 158.94 60.34
164 INT14740 Gene_expression of TGFB1 10 272 0.78 168.48 60.18
165 INT546 Binding of ALB 2 311 0.48 85.98 60.14
166 INT50672 Positive_regulation of CPOX 2 205 0.44 125.93 60.06
167 INT1536 Negative_regulation of NA 1 244 0.55 52.67 59.79
168 INT6623 Gene_expression of NA 2 231 0.78 45.78 59.36
169 INT1759 Gene_expression of TIMP1 2 267 0.77 133.87 59.29
170 INT11491 Positive_regulation of KNG1 2 128 0.67 60.41 58.74
171 INT169926 Positive_regulation of Gopc 2 416 0.46 157.8 58.67
172 INT5710 Negative_regulation of Localization of Lhb 20 146 0.57 20.51 58.33
173 INT20964 Gene_expression of OPRK1 1 96 0.78 23.54 58.18
174 INT73048 Gene_expression of MMP9 5 268 0.77 159.75 57.81
175 INT48232 Gene_expression of MMP1 3 245 0.78 96.31 57.72
176 INT129303 Positive_regulation of NAV1 1 54 0.70 36.92 57.45
177 INT4509 Gene_expression of IGG 3 426 0.76 293.69 56.64
178 INT5453 Regulation of Localization of POMC 2 114 0.62 20.56 56.34
179 INT1200 Negative_regulation of Ins1 2 274 0.58 155.17 56.14
180 INT96937 Gene_expression of Mmp9 5 191 0.75 150.3 56.01
181 INT1782 Regulation of Gh1 2 125 0.62 22 55.74
182 INT1579 Gene_expression of PRL 12 279 0.78 119.2 55.41
183 INT78899 Gene_expression of CCL5 1 155 0.77 84.02 55.09
184 INT49436 Binding of TRPV1 4 145 0.48 38.35 55.08
185 INT251 Regulation of INS 7 398 0.62 232.47 55.04
186 INT82650 Gene_expression of Bcl2 1 312 0.78 211.71 55.03
187 INT63975 Positive_regulation of Il10 1 175 0.68 134.13 54.69
188 INT117223 Gene_expression of TLR4 36 348 0.78 206.18 54.42
189 INT2276 Regulation of Ins1 1 234 0.61 103.78 54.05
190 INT5509 Positive_regulation of Localization of Crh 1 91 0.70 30.65 53.92
191 INT3213 Gene_expression of Ins1 4 511 0.76 357.59 53.32
192 INT9234 Negative_regulation of Gene_expression of IL6 1 171 0.59 101.61 53.15
193 INT1032 Regulation of Ca2 1 202 0.52 54.91 53.03
194 INT6034 Binding of Gabrg1 3 115 0.47 17.48 51.92
195 INT19775 Localization of Il1 1 183 0.78 145.5 50.91
196 INT4985 Positive_regulation of Tac1 4 81 0.69 35.79 50.67
197 INT2197 Gene_expression of Gnrh1 18 184 0.78 40.04 50.57
198 INT1199 Positive_regulation of INS 3 579 0.70 399.64 50.43
199 INT7287 Positive_regulation of Transcription of Penk 1 103 0.70 19.81 50.37
200 INT1232 Positive_regulation of Pdpk1 3 78 0.42 24.33 50.17
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