J:Rinsho Shinkeigaku

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT165183 Ifnb1 Positive_regulation of P2rx4 1 2 0.04 1.73 1.73
2 INT123468 IL6 Regulation of CSF2 1 1 0.25 1.22 0.26
3 INT52629 Binding of AVP and NMS 1 1 0.04 1.04 0.21

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT155 Positive_regulation of Prl 2 1233 0.70 317.93 457.82
2 INT162 Regulation of Prl 2 794 0.62 165.01 322.24
3 INT49750 Negative_regulation of CPOX 2 735 0.58 360.06 274.19
4 INT738 Regulation of POMC 1 459 0.62 111.19 243.74
5 INT10194 Positive_regulation of IL6 7 702 0.70 600.62 183.38
6 INT15516 Gene_expression of Crp 3 711 0.77 615.33 173.09
7 INT739 Negative_regulation of POMC 2 358 0.59 102.28 166.77
8 INT15515 Positive_regulation of Crp 3 700 0.70 604.24 150.15
9 INT425 Localization of PRL 1 455 0.81 189.64 144.8
10 INT2867 Gene_expression of CALCA 1 247 0.78 78.78 138.47
11 INT1530 Regulation of Gh 1 382 0.61 115.96 112.47
12 INT915 Positive_regulation of PRL 1 342 0.70 141.96 104.31
13 INT18009 Positive_regulation of CRP 1 518 0.70 553.03 103.74
14 INT65500 Gene_expression of App 1 605 0.78 429.94 98.31
15 INT11587 Gene_expression of CSF2 3 645 0.78 544.38 93.89
16 INT214 Localization of AVP 7 370 0.81 208.51 91.09
17 INT1724 Negative_regulation of ACE 1 437 0.59 315.64 74.48
18 INT9489 Gene_expression of SFTPA1 1 112 0.66 55.38 66.45
19 INT4960 Positive_regulation of CSF2 9 285 0.70 256.73 65.73
20 INT3375 Gene_expression of IGHE 1 535 0.77 387.47 65.46
21 INT5095 Localization of Ghrh 1 185 0.81 28.09 62.08
22 INT1579 Gene_expression of PRL 1 279 0.78 119.2 55.41
23 INT249 Localization of GHRH 1 215 0.80 78.02 51.87
24 INT9556 Negative_regulation of NAV1 1 47 0.59 28.49 49.33
25 INT671 Positive_regulation of Cea 1 221 0.69 164.5 47.79
26 INT374 Positive_regulation of Ldha 1 212 0.70 107.08 47.43
27 INT847 Regulation of Lhb 1 131 0.61 22.08 46.54
28 INT42980 Gene_expression of GAD1 1 139 0.69 94.77 45.11
29 INT4216 Gene_expression of CD40LG 3 328 0.78 256.02 44.23
30 INT66383 Phosphorylation of Prkaca 1 143 0.80 30.85 43.38
31 INT613 Gene_expression of Alb 1 268 0.78 149.84 42.78
32 INT4004 Gene_expression of IGHG3 2 321 0.71 221.03 42.33
33 INT3987 Positive_regulation of IGHE 3 316 0.70 283.2 40.16
34 INT64558 Negative_regulation of Nos1 1 88 0.58 26.76 36.78
35 INT9082 Positive_regulation of ESR1 2 238 0.69 148.51 36.69
36 INT1624 Gene_expression of Cea 1 212 0.76 180.44 34.21
37 INT28361 Gene_expression of TP53 2 443 0.78 384.86 28.8
38 INT3286 Positive_regulation of Gpt 1 90 0.69 45.08 28.34
39 INT2393 Positive_regulation of Mb 1 174 0.69 93.59 26.79
40 INT3760 Positive_regulation of ALB 1 142 0.70 87.46 26.7
41 INT12124 Gene_expression of MAPK1 1 141 0.75 82.4 25.58
42 INT17275 Gene_expression of HIVEP1 1 267 0.75 232.07 24.06
43 INT682 Negative_regulation of AVP 2 97 0.59 50.67 23.91
44 INT1704 Positive_regulation of PCa 1 68 0.59 34.92 23.36
45 INT16996 Gene_expression of PRTN3 5 113 0.75 85.61 22.57
46 INT4369 Gene_expression of Ldha 1 157 0.76 88.12 22.45
47 INT756 Gene_expression of C3 1 138 0.75 100.6 19.2
48 INT5372 Localization of LHB 1 55 0.68 9.47 19
49 INT18010 Positive_regulation of CD40LG 2 122 0.70 100.8 18.46
50 INT3952 Negative_regulation of ALB 1 116 0.59 72.18 18.35
51 INT20631 Positive_regulation of CHKB 4 166 0.69 109.86 17.92
52 INT9358 Positive_regulation of HTR1B 1 26 0.67 11 17.51
53 INT7580 Positive_regulation of Mbp 4 54 0.70 23.37 17.14
54 INT1721 Negative_regulation of HP 1 148 0.42 86.82 16.89
55 INT6129 Positive_regulation of Localization of AVP 1 63 0.70 30.44 16.64
56 INT984 Positive_regulation of Localization of GHRH 1 58 0.70 12.66 16.51
57 INT10721 Gene_expression of BDNF-AS 1 119 0.76 72.8 16.29
58 INT75929 Gene_expression of IL9 1 61 0.43 24.71 16.17
59 INT16167 Negative_regulation of DMD 1 186 0.57 108.71 15.25
60 INT16166 Positive_regulation of DMD 1 348 0.67 133.22 15.06
61 INT505 Positive_regulation of GPT 2 89 0.67 69.38 14.94
62 INT8798 Positive_regulation of Csrp1 3 61 0.69 63.86 14.14
63 INT11696 Gene_expression of HLA-A 1 50 0.78 41.25 14.1
64 INT11069 Positive_regulation of Pf4 1 35 0.68 27.7 13.96
65 INT9649 Positive_regulation of LPA 2 105 0.69 74.75 13.89
66 INT19399 Gene_expression of Rf 1 43 0.36 33.39 13.53
67 INT11071 Positive_regulation of PPBP 1 43 0.68 26.85 13.43
68 INT1125 Positive_regulation of IGHG3 7 130 0.69 112.07 13.18
69 INT4137 Positive_regulation of C3 1 73 0.69 48.57 12.63
70 INT541 Positive_regulation of MBP 4 31 0.67 28.56 12.24
71 INT10847 Gene_expression of LAMC2 1 39 0.75 27 12.09
72 INT122053 Positive_regulation of P2rx4 1 16 0.69 13.02 11.98
73 INT28872 Positive_regulation of CSRP1 3 49 0.70 47.23 11.7
74 INT373 Regulation of Ldha 3 37 0.61 17.86 11.41
75 INT142735 Regulation of RLS 1 33 0.53 45.83 11.35
76 INT17349 Negative_regulation of Akr1b1 1 41 0.59 27.03 10.65
77 INT58904 Localization of TH1L 1 40 0.68 27.11 10.52
78 INT11238 Positive_regulation of ADA 6 33 0.70 39.7 9.98
79 INT9548 Gene_expression of CHKB 1 99 0.65 50.86 9.03
80 INT23147 Negative_regulation of MRI1 1 26 0.38 14.33 8.96
81 INT860 Regulation of ALB 1 48 0.60 25.11 8.95
82 INT2280 Negative_regulation of TNFAIP1 1 70 0.43 69.43 8.36
83 INT4663 Positive_regulation of Ada 1 17 0.69 9.48 7.93
84 INT136304 Negative_regulation of Aqp4 1 54 0.59 48.42 7.4
85 INT25 Positive_regulation of LAMC2 1 19 0.67 8.64 7.06
86 INT8541 Gene_expression of Csrp1 1 42 0.76 23.72 6.9
87 INT10917 Positive_regulation of ITGAM 1 31 0.67 16.39 6.69
88 INT13139 Negative_regulation of Cd4 1 27 0.47 17.49 6.61
89 INT90461 Negative_regulation of DRD2 1 21 0.53 8.35 6.55
90 INT16997 Binding of PRTN3 3 34 0.48 33.44 6.45
91 INT48308 Binding of PLP1 1 7 0.48 9.59 6.09
92 INT2890 Positive_regulation of MB 3 39 0.70 29.58 6.01
93 INT677 Positive_regulation of CST3 2 20 0.67 17.47 6
94 INT25271 Positive_regulation of MTG1 1 21 0.67 13.59 5.96
95 INT28362 Gene_expression of REG1A 2 29 0.75 9.69 5.95
96 INT30206 Negative_regulation of ADA 1 17 0.59 10.03 5.63
97 INT8866 Positive_regulation of TAT 3 30 0.67 18.06 5.57
98 INT13396 Gene_expression of DMD 1 125 0.75 57.81 5.45
99 INT19768 Negative_regulation of LAMC2 1 11 0.57 10.54 5.32
100 INT68202 Gene_expression of ADA 3 26 0.68 23.15 5.18
101 INT14501 Gene_expression of CST3 1 28 0.75 25.77 5.16
102 INT5297 Regulation of IFNA2 1 20 0.56 10.81 5.13
103 INT26459 Regulation of Prl 1 14 0.62 7.27 4.92
104 INT43707 Positive_regulation of CCBE1 3 11 0.07 8.22 4.86
105 INT48246 Gene_expression of PLP1 1 18 0.64 10.33 4.73
106 INT12324 Positive_regulation of PRTN3 1 26 0.70 18.82 4.55
107 INT133231 Regulation of PYCARD 1 18 0.39 5.02 4.44
108 INT35599 Negative_regulation of Nqo1 1 25 0.54 4.6 4.42
109 INT67279 Localization of PRTN3 1 11 0.50 14.18 4.3
110 INT165182 Gene_expression of P2ry12 2 4 0.65 4.29 4.08
111 INT134590 Localization of ADA 1 7 0.65 8.43 3.96
112 INT44323 Positive_regulation of F8 2 32 0.60 24.88 3.89
113 INT16165 Regulation of DMD 1 114 0.60 35.13 3.64
114 INT78203 Gene_expression of PMP22 1 12 0.63 7.49 3.58
115 INT35143 Negative_regulation of ANGPTL5 1 28 0.54 18.59 3.14
116 INT26273 Negative_regulation of RYR1 3 18 0.43 7.64 3.11
117 INT78317 Regulation of CACNA1A 2 8 0.62 7.68 3.08
118 INT4873 Positive_regulation of FCGR3A 2 21 0.49 14.35 2.89
119 INT34595 Negative_regulation of Reg1 1 12 0.36 4.29 2.77
120 INT44426 Localization of BRD2 2 6 0.78 4.02 2.59
121 INT23954 Negative_regulation of Mb 1 24 0.49 11.27 2.55
122 INT66002 Binding of LAMC2 1 9 0.47 4.5 2.54
123 INT124417 Gene_expression of Mthfr 1 8 0.60 8.65 2.53
124 INT640 Regulation of CST3 1 9 0.60 4.04 2.26
125 INT27217 Negative_regulation of LYZ 1 6 0.42 3.1 2.26
126 INT161575 Localization of CACNA1A 2 4 0.75 5.28 2.26
127 INT49082 Gene_expression of MPZ 1 15 0.65 31.26 2.24
128 INT3823 Positive_regulation of ALPI 1 27 0.69 19.49 2.15
129 INT114330 Binding of MPZ 1 21 0.32 25.58 2.14
130 INT97308 Gene_expression of TPO 1 15 0.65 13.26 2.12
131 INT101582 Negative_regulation of SNAP25 1 9 0.57 4.34 2.12
132 INT58564 Positive_regulation of Dpa 1 2 0.09 1.33 2.12
133 INT49210 Transcription of GAD1 1 8 0.60 3.48 2.06
134 INT119803 Localization of Cir1 1 12 0.70 3.39 2
135 INT42497 Regulation of Negative_regulation of POMC 1 4 0.44 0.63 1.99
136 INT21941 Regulation of CALR 1 7 0.53 3.88 1.96
137 INT14500 Positive_regulation of Gene_expression of CST3 1 9 0.67 7.46 1.87
138 INT99444 Positive_regulation of Proc 1 15 0.45 9.18 1.75
139 INT16150 Positive_regulation of NKG7 2 10 0.69 10.26 1.73
140 INT63812 Gene_expression of H1FNT 1 14 0.06 8.41 1.67
141 INT139009 Positive_regulation of Localization of Cir1 1 10 0.44 2.98 1.55
142 INT161574 Localization of CENPJ 1 7 0.73 6.11 1.54
143 INT124418 Gene_expression of Mthfr 1 4 0.60 4.52 1.54
144 INT164512 Regulation of MPZ 1 12 0.30 8.38 1.53
145 INT11710 Positive_regulation of SERPINC1 1 6 0.59 6.15 1.47
146 INT125800 Gene_expression of P4HB 1 5 0.47 5.4 1.47
147 INT18156 Gene_expression of Fap 1 18 0.73 27.02 1.46
148 INT16184 Negative_regulation of CHKB 1 20 0.53 10.61 1.42
149 INT130343 Gene_expression of CTNND2 1 5 0.75 6.98 1.38
150 INT105569 Binding of IGFALS 1 13 0.25 17.31 1.36
151 INT124419 Gene_expression of Naad5 1 1 0.00 1.58 1.3
152 INT110871 Positive_regulation of Cms1 1 8 0.15 7.92 1.27
153 INT14727 Regulation of FN1 1 13 0.45 5.95 1.26
154 INT62801 Gene_expression of IL1F10 1 1 0.59 1.02 1.24
155 INT118817 Positive_regulation of Apoc4 1 6 0.45 6.44 1.23
156 INT13397 Localization of DMD 1 21 0.78 7.96 1.08
157 INT25971 Positive_regulation of EBI3 3 5 0.19 5.01 1.07
158 INT49505 Binding of NOTCH3 2 6 0.47 6.4 1.03
159 INT22804 Positive_regulation of ALDOC 5 8 0.41 8.07 1.02
160 INT104284 Positive_regulation of Notch3 1 7 0.50 5.57 0.99
161 INT88466 Regulation of Gene_expression of Ldha 1 5 0.33 4.07 0.97
162 INT21940 Positive_regulation of CALR 1 15 0.40 17.42 0.95
163 INT78316 Regulation of TGM6 1 3 0.16 3.09 0.95
164 INT103328 Binding of F8 1 9 0.44 11.89 0.93
165 INT85624 Gene_expression of GJB1 1 5 0.78 3.03 0.93
166 INT46403 Gene_expression of ATN1 1 2 0.75 3.33 0.93
167 INT85623 Gene_expression of ATXN1 1 6 0.58 5.14 0.9
168 INT7620 Localization of TPO 1 4 0.26 5.35 0.88
169 INT88642 Negative_regulation of Localization of BRD2 1 2 0.57 2.15 0.69
170 INT59137 Protein_catabolism of CTSB 1 5 0.96 3.92 0.62
171 INT169167 Positive_regulation of GREM1 1 1 0.08 1.83 0.6
172 INT9555 Negative_regulation of KCNQ2 1 3 0.57 0.92 0.56
173 INT63814 Gene_expression of NKG7 1 3 0.58 2.76 0.54
174 INT11867 Positive_regulation of Positive_regulation of TAT 2 2 0.49 2.02 0.54
175 INT74630 Negative_regulation of ACADVL 1 8 0.58 2.49 0.53
176 INT28363 Gene_expression of NRSN1 3 8 0.45 8.66 0.53
177 INT69142 Positive_regulation of Atxn3 1 3 0.50 1.52 0.53
178 INT117796 Binding of CPM 1 5 0.48 2.79 0.45
179 INT45352 Negative_regulation of THTPA 1 2 0.37 1.45 0.45
180 INT23645 Regulation of Scnn1a 1 2 0.23 1.18 0.44
181 INT94347 Gene_expression of DYSF 1 4 0.75 3.25 0.41
182 INT122704 Positive_regulation of AEBP1 1 1 0.40 1 0.36
183 INT130344 Gene_expression of APOH 1 3 0.34 2.87 0.32
184 INT19742 Binding of PPP1R3A 1 2 0.04 0.92 0.3
185 INT164511 Negative_regulation of Binding of MPZ 1 2 0.36 1.64 0.29
186 INT118818 Binding of HOXA10 1 1 0.10 1.26 0.29
187 INT60645 Regulation of COL4A4 2 1 0.22 0.51 0.27
188 INT82857 Negative_regulation of ACOT8 1 3 0.19 1.1 0.25
189 INT63178 Positive_regulation of Rhox10 1 1 0.01 0.74 0.25
190 INT144112 Regulation of Binding of CPM 1 1 0.26 0.75 0.22
191 INT144113 Binding of STX2 1 1 0.47 0.75 0.21
192 INT20608 Positive_regulation of Regulation of CST3 1 1 0.01 1.23 0.21
193 INT28360 Gene_expression of PSMD10 1 1 0.36 0.79 0.17
194 INT19741 Positive_regulation of PPP1R3A 1 2 0.40 0.91 0.16
195 INT136185 Positive_regulation of Binding of F8 1 2 0.64 1.4 0.14
196 INT58565 Localization of Bh4p 1 2 0.03 0.98 0.12
197 INT145975 Binding of TUBA1B 1 1 0.36 1.2 0.09
198 INT145976 Positive_regulation of TUBA1B 1 1 0.49 1.2 0.09
199 INT103565 Negative_regulation of Cps1 1 1 0.13 1.17 0.07
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