J:Stem Cells International

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT333246 Binding of Cxcr4 and Cxcl12 3 1 0.34 0.99 0.27
2 INT249962 Binding of KIT and KITLG 6 2 0.19 3.69 0.17
3 INT337727 ADAMTS2 Positive_regulation of Gene_expression of KIT 1 1 0.02 0 0.03
4 INT337751 ADAMTS2 Positive_regulation of Gene_expression of Nkx6-1 1 1 0.04 0 0.03
5 INT337737 ADAMTS2 Positive_regulation of Gene_expression of PDX1 1 2 0.02 0 0.03
6 INT337728 ADAMTS2 Positive_regulation of Gene_expression of INS 1 1 0.02 0 0.03
7 INT337735 ADAMTS2 Positive_regulation of Gene_expression of GCK 1 1 0.01 0 0
8 INT354566 F2 Positive_regulation of PRNP 1 1 0.00 0.05 0
9 INT337733 ADAMTS2 Positive_regulation of Gene_expression of GK 1 1 0.00 0 0
10 INT337729 PDX1 Regulation of Gene_expression of INS 1 2 0.29 0.28 0
11 INT337738 PDX1 Regulation of Positive_regulation of INS 1 1 0.21 0.28 0
12 INT339676 CSF2 Positive_regulation of HGF 1 1 0.08 0.46 0
13 INT337734 ADAMTS2 Positive_regulation of Gene_expression of SLC2A2 1 1 0.01 0 0
14 INT337730 PDX1 Regulation of INS 1 1 0.21 0.28 0
15 INT339675 CSF2 Positive_regulation of Localization of FUT1 1 1 0.01 0.42 0
16 INT337732 KITLG Positive_regulation of KIT 1 1 0.03 0 0
17 INT337731 Binding of KIT and ADAMTS2 1 1 0.01 0.12 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT5235 Negative_regulation of TNF 1 924 0.59 772.91 331.98
2 INT68684 Gene_expression of VEGFA 1 2371 0.78 1742.52 259.2
3 INT10194 Positive_regulation of IL6 2 702 0.70 600.62 183.38
4 INT812 Localization of INS 14 1026 0.81 515.6 145.31
5 INT85640 Gene_expression of Tg(CAG-EGFP)D4Nagy 6 1138 0.72 311.58 119.18
6 INT60526 Gene_expression of IL10 1 449 0.78 292.71 107.84
7 INT3038 Gene_expression of INS 19 1583 0.78 1174.16 107.01
8 INT11587 Gene_expression of CSF2 3 645 0.78 544.38 93.89
9 INT102546 Gene_expression of Ccl2 1 197 0.78 192.8 67.41
10 INT4960 Positive_regulation of CSF2 2 285 0.70 256.73 65.73
11 INT17401 Gene_expression of IGF1 1 475 0.78 232.18 62.07
12 INT48891 Positive_regulation of Il10 1 143 0.70 101.42 56.72
13 INT96937 Gene_expression of Mmp9 1 191 0.75 150.3 56.01
14 INT1199 Positive_regulation of INS 9 579 0.70 399.64 50.43
15 INT26500 Gene_expression of MMP2 1 201 0.78 110.57 46.9
16 INT1322 Positive_regulation of Localization of INS 2 293 0.70 120.86 45.98
17 INT42980 Gene_expression of GAD1 3 139 0.69 94.77 45.11
18 INT16364 Gene_expression of HLA-DRA 3 234 0.78 118.81 45.01
19 INT3252 Negative_regulation of INS 2 428 0.59 271.65 39.52
20 INT3758 Gene_expression of ALB 4 326 0.78 184.65 38.75
21 INT9094 Gene_expression of COL7A1 2 277 0.77 143.42 38.73
22 INT3253 Negative_regulation of Localization of INS 2 205 0.59 130.39 36.61
23 INT101992 Localization of VEGFA 2 413 0.81 258.23 36.15
24 INT7675 Gene_expression of ENG 1 146 0.77 45.35 34.6
25 INT52350 Gene_expression of CD14 4 184 0.75 71.37 33.13
26 INT99610 Localization of MMP9 2 126 0.79 48.46 32.67
27 INT88318 Gene_expression of CXCR4 1 208 0.77 189.67 31.72
28 INT10915 Gene_expression of ITGAM 3 164 0.78 92.42 29.78
29 INT11554 Negative_regulation of CSF2 1 129 0.59 108.55 29.44
30 INT28361 Gene_expression of TP53 1 443 0.78 384.86 28.8
31 INT14690 Localization of CSF2 4 124 0.80 85.17 27.26
32 INT9647 Gene_expression of PROC 1 163 0.65 89.76 26.75
33 INT62710 Gene_expression of HGF 1 160 0.78 88.27 26.14
34 INT70048 Positive_regulation of Gene_expression of IL10 2 90 0.55 71.34 25.66
35 INT4535 Localization of PROC 6 106 0.73 76.24 21.1
36 INT138696 Positive_regulation of Ccl2 1 57 0.67 59.57 19.58
37 INT28215 Gene_expression of CDKN1A 1 196 0.76 113.9 18.3
38 INT171060 Gene_expression of PDX1 14 72 0.75 72.57 17.97
39 INT113602 Positive_regulation of Gene_expression of Ccl2 1 48 0.70 48.71 17.85
40 INT2120 Gene_expression of CD79A 3 159 0.78 111.69 17.16
41 INT1767 Positive_regulation of PROC 2 83 0.67 54.14 17
42 INT170335 Gene_expression of INCENP 3 176 0.54 91.62 15.31
43 INT26501 Positive_regulation of Gene_expression of MMP2 1 51 0.67 39 15.16
44 INT24670 Gene_expression of FGF2 2 121 0.78 85.64 15.12
45 INT72127 Protein_catabolism of MMRN1 1 68 0.52 56 14.13
46 INT78472 Gene_expression of CDKN2A 1 223 0.78 173.76 13.61
47 INT8210 Positive_regulation of Gene_expression of INS 4 188 0.68 146.57 12.83
48 INT3040 Gene_expression of MIA3 6 81 0.24 53.61 12.62
49 INT24876 Gene_expression of CD34 6 172 0.78 91.02 12.39
50 INT69029 Gene_expression of PTPRC 3 127 0.75 74.26 11.57
51 INT85015 Gene_expression of ADM 1 29 0.73 30.75 10.21
52 INT113605 Negative_regulation of Gene_expression of Mmp9 1 25 0.41 22.92 9.98
53 INT82829 Gene_expression of COMP 1 104 0.78 57 9.81
54 INT144689 Regulation of RCT 1 49 0.53 25.91 9.6
55 INT6510 Gene_expression of AFP 5 130 0.78 119.2 9.19
56 INT1118 Gene_expression of C6orf25 1 73 0.77 47.24 9.1
57 INT14301 Binding of CSF2 1 82 0.48 67.95 8.98
58 INT69264 Gene_expression of KIT 8 207 0.78 179.41 8.95
59 INT34777 Localization of IGF1 1 82 0.80 42.68 8.62
60 INT17024 Gene_expression of COL1A2 1 69 0.77 36.38 8.29
61 INT126478 Gene_expression of Cxcl12 1 78 0.77 58.69 8.01
62 INT117543 Regulation of Gene_expression of CD14 1 21 0.59 6.66 7.67
63 INT4606 Regulation of Gene_expression of INS 1 67 0.61 54.69 7.53
64 INT8793 Gene_expression of H2 1 58 0.75 26.36 7.07
65 INT83531 Gene_expression of KITLG 1 54 0.65 26 7.07
66 INT28122 Gene_expression of MSC 9 111 0.58 26.83 6.57
67 INT86805 Localization of HGF 4 49 0.71 28.48 6.35
68 INT126481 Gene_expression of Cxcr4 3 69 0.77 34.99 6
69 INT147263 Regulation of Gene_expression of Tg(CAG-EGFP)D4Nagy 1 51 0.53 15.32 5.86
70 INT56149 Localization of CD8A 1 56 0.74 30.41 5.75
71 INT28088 Binding of Alb 1 34 0.47 11.06 5.48
72 INT76313 Gene_expression of CD38 1 30 0.64 20.74 5.27
73 INT170470 Binding of CD14 1 27 0.35 14.89 5.16
74 INT106971 Positive_regulation of Gene_expression of GAD1 1 19 0.58 10.89 4.59
75 INT103155 Gene_expression of KDR 1 78 0.66 50.53 4.38
76 INT111477 Gene_expression of KRT7 2 90 0.74 86.76 4.07
77 INT168418 Positive_regulation of RCT 3 32 0.55 20.2 4.07
78 INT75688 Binding of KITLG 2 24 0.30 11.73 4.06
79 INT126477 Gene_expression of Sdf2l1 20 43 0.66 22.02 3.97
80 INT149259 Gene_expression of RCT 1 38 0.67 15.73 3.87
81 INT62784 Gene_expression of NT5E 7 46 0.65 15.95 3.72
82 INT9144 Localization of MSC 8 18 0.56 10.17 3.69
83 INT19491 Gene_expression of CD19 3 44 0.75 28.8 3.47
84 INT64766 Gene_expression of TWIST1 10 41 0.76 37.89 3.4
85 INT139366 Gene_expression of PROM1 1 98 0.77 67.84 3.39
86 INT160251 Gene_expression of Myo5a 1 48 0.63 37.14 3.16
87 INT85809 Gene_expression of BMP2 2 46 0.78 9.91 3.05
88 INT200470 Positive_regulation of Gene_expression of COMP 1 13 0.69 13.73 2.93
89 INT37715 Positive_regulation of MSC 3 34 0.48 10.52 2.92
90 INT59454 Regulation of Gene_expression of CSF2 1 22 0.52 19.67 2.69
91 INT171346 Gene_expression of TNFSF12 1 7 0.58 4.19 2.62
92 INT8111 Localization of EPO 1 32 0.81 19.53 2.54
93 INT74527 Positive_regulation of PDGFB 1 14 0.38 13.31 2.54
94 INT3315 Negative_regulation of Positive_regulation of INS 1 31 0.57 14.73 2.27
95 INT85085 Positive_regulation of KIT 3 36 0.53 30.08 2.17
96 INT170469 Gene_expression of THY1 9 66 0.65 11.9 2.15
97 INT94835 Localization of NUDT6 1 13 0.52 11.57 2
98 INT48880 Positive_regulation of TWIST1 3 15 0.59 8.6 1.98
99 INT133269 Positive_regulation of PDX1 6 10 0.54 9.77 1.9
100 INT171059 Localization of PDX1 1 8 0.56 6.7 1.9
101 INT167203 Binding of PRNP 1 25 0.48 20.09 1.84
102 INT85084 Gene_expression of KRT19 3 66 0.73 42.56 1.82
103 INT160533 Gene_expression of NUDT6 1 24 0.20 18.6 1.7
104 INT29557 Localization of MIA3 1 23 0.57 6.78 1.6
105 INT28123 Positive_regulation of Gene_expression of MSC 2 17 0.43 4.02 1.54
106 INT21682 Binding of CD34 1 18 0.47 13.19 1.47
107 INT39050 Positive_regulation of PGF 1 14 0.49 8.05 1.43
108 INT210220 Positive_regulation of Sdf2l1 2 13 0.51 7.88 1.4
109 INT105921 Localization of FUT1 1 13 0.23 3.92 1.39
110 INT183065 Positive_regulation of Gene_expression of PDX1 2 7 0.54 6.58 1.29
111 INT178494 Gene_expression of Angpt1 3 10 0.37 9.77 1.28
112 INT143759 Gene_expression of SOX2 1 46 0.55 11.12 1.24
113 INT53261 Gene_expression of exf 1 5 0.07 4.93 1.24
114 INT216380 Gene_expression of PAX6 4 49 0.78 15.63 1.22
115 INT109078 Positive_regulation of ANGPT1 1 7 0.22 3.08 1.21
116 INT165564 Positive_regulation of Gene_expression of Sdf2l1 12 6 0.59 9.54 1.17
117 INT183046 Transcription of INS 1 25 0.70 11.14 1.13
118 INT172809 Gene_expression of ISL1 4 33 0.40 21.63 1.12
119 INT200793 Gene_expression of Csf3r 2 5 0.52 3.16 1
120 INT233330 Localization of LEFTY2 1 4 0.15 4.46 0.99
121 INT39415 Gene_expression of HBN1 1 33 0.43 19.31 0.93
122 INT225094 Localization of ADM 1 5 0.63 3.89 0.91
123 INT226691 Positive_regulation of Gene_expression of Cxcr4 2 14 0.57 7.9 0.9
124 INT173626 Negative_regulation of MSC 3 9 0.47 3.28 0.87
125 INT226688 Negative_regulation of Sdf2l1 2 14 0.50 6.52 0.72
126 INT210219 Localization of Sdf2l1 1 5 0.64 3.42 0.7
127 INT7723 Localization of Hgf 1 10 0.46 6.28 0.68
128 INT305315 Positive_regulation of Positive_regulation of PROC 1 3 0.49 1.52 0.64
129 INT204254 Localization of KIT 2 8 0.73 6.78 0.61
130 INT65701 Localization of KITLG 1 13 0.65 2.46 0.58
131 INT176891 Negative_regulation of Localization of CD8A 1 4 0.22 2.58 0.49
132 INT128376 Binding of KIT 4 26 0.48 14.24 0.47
133 INT87819 Localization of CD34 4 21 0.81 7.69 0.47
134 INT140436 Binding of TWIST1 2 5 0.39 2.34 0.47
135 INT3039 Positive_regulation of Gene_expression of MIA3 1 11 0.12 7.32 0.46
136 INT313617 Positive_regulation of Pdgfb 1 4 0.35 1.53 0.46
137 INT178497 Positive_regulation of Gene_expression of Angpt1 1 4 0.19 3.65 0.39
138 INT224924 Binding of TARM1 1 4 0.18 3.42 0.39
139 INT228271 Localization of Fgf7 1 2 0.28 1.59 0.39
140 INT303100 Positive_regulation of Gene_expression of Csf3r 1 2 0.31 0.58 0.35
141 INT185840 Positive_regulation of Localization of PDX1 1 2 0.27 0.78 0.33
142 INT239566 Gene_expression of SDF2L1 1 2 0.25 0.47 0.33
143 INT157605 Localization of COL3A1 1 3 0.80 0.55 0.29
144 INT25465 Positive_regulation of ISL1 1 6 0.15 3.59 0.26
145 INT205087 Positive_regulation of Gene_expression of ISL1 1 4 0.26 3.86 0.19
146 INT339677 Positive_regulation of Csf3r 1 1 0.05 0.24 0.17
147 INT315967 Negative_regulation of Msc 1 3 0.35 1.86 0.15
148 INT238858 Gene_expression of GK 1 4 0.08 2.18 0.14
149 INT279393 Regulation of Gene_expression of MSC 1 2 0.07 0.36 0.14
150 INT337742 Gene_expression of SLC2A2 1 2 0.38 1.72 0.14
151 INT232508 Regulation of Gene_expression of CD34 1 4 0.43 2.73 0.13
152 INT51883 Negative_regulation of ADAMTS2 1 3 0.15 0.74 0.11
153 INT341478 Gene_expression of SUMO1 2 1 0.02 0.68 0.11
154 INT352543 Phosphorylation of MSC 1 1 0.31 0.59 0.1
155 INT282593 Gene_expression of KLF4 1 8 0.61 1.09 0.09
156 INT273647 Positive_regulation of Localization of FUT1 1 3 0.09 0.65 0.09
157 INT347975 Positive_regulation of AGGF1 1 2 0.03 0.99 0.07
158 INT262951 Transcription of PAX6 1 6 0.72 3.33 0.06
159 INT229324 Gene_expression of GCK 1 3 0.35 0.48 0.06
160 INT289722 Localization of Pgf 1 3 0.45 0.63 0.04
161 INT339688 Localization of TARM1 1 1 0.04 0.87 0.04
162 INT235783 Positive_regulation of Gene_expression of PAX6 1 7 0.50 1.59 0.03
163 INT244776 Gene_expression of Nkx6-1 1 2 0.75 0 0.03
164 INT250742 Negative_regulation of SLC2A2 1 2 0.09 0.86 0.03
165 INT317061 Regulation of Gene_expression of KRT7 1 2 0.19 0.99 0.03
166 INT286173 Gene_expression of ADAMTS2 6 2 0.13 0.49 0.03
167 INT352542 Transcription of PDX1 1 1 0.67 0.2 0.03
168 INT339690 Gene_expression of LIN28A 1 1 0.16 0.17 0.03
169 INT352541 Transcription of ISL1 1 1 0.36 0.2 0.03
170 INT183053 Negative_regulation of Gene_expression of PDX1 1 4 0.46 0.76 0
171 INT239661 Negative_regulation of NR2E3 1 3 0.06 0.16 0
172 INT192960 Regulation of Gene_expression of KIT 1 3 0.45 4.16 0
173 INT132820 Positive_regulation of Localization of KITLG 1 2 0.39 0.11 0
174 INT286174 Positive_regulation of ADAMTS2 3 2 0.13 0.48 0
175 INT272972 Regulation of ADAMTS2 5 2 0.02 1.21 0
176 INT337743 Negative_regulation of Positive_regulation of ADAMTS2 2 1 0.02 0 0
177 INT337746 Positive_regulation of Gene_expression of ADAMTS2 1 1 0.03 0 0
178 INT337744 Positive_regulation of Regulation of ADAMTS2 1 1 0.03 0.26 0
179 INT337739 Phosphorylation of PDX1 1 1 0.44 0 0
180 INT339687 Positive_regulation of ARHGEF1 1 1 0.03 0.44 0
181 INT337748 Negative_regulation of Localization of ADAMTS2 2 1 0.02 0.48 0
182 INT337749 Localization of ADAMTS2 3 1 0.04 0.68 0
183 INT339689 Positive_regulation of Positive_regulation of ARHGEF1 1 1 0.03 0.44 0
184 INT337741 Positive_regulation of Positive_regulation of ADAMTS2 1 1 0.03 0.27 0
185 INT337740 Positive_regulation of Phosphorylation of PDX1 1 1 0.27 0 0
186 INT337750 Binding of ADAMTS2 1 1 0.02 0 0
187 INT337745 Negative_regulation of Positive_regulation of PDX1 1 1 0.23 0 0
188 INT337747 Positive_regulation of Localization of KIT 1 1 0.32 0 0
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