J:The Journal of Biological Chemistry

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT341218 Binding of Eif4e and Eif4ebp1 1 16 0.19 2.65 1.23
2 INT289465 IRF6 Positive_regulation of IL1B 3 4 0.05 0.9 1.16
3 INT313435 Syp Regulation of Th 1 9 0.43 1.6 0.64
4 INT236003 Binding of HTR1A and Grin1 1 2 0.01 0.7 0.63
5 INT168128 Oprm1 Regulation of Mir190 1 2 0.11 0 0.54
6 INT322048 Prkdc Negative_regulation of Col7a1 1 1 0.00 0.45 0.5
7 INT289462 Negative_regulation of IRF6 Positive_regulation of IL1B 2 1 0.04 0.31 0.48
8 INT168699 Binding of Nedd4 and Tyr 1 2 0.02 0.45 0.46
9 INT168130 Mir190 Positive_regulation of Phosphorylation of Yy1 1 1 0.54 0 0.45
10 INT168131 Phosphorylation of Yy1 Positive_regulation of Gene_expression of Mir190 1 1 0.32 0 0.45
11 INT341226 Gopc Regulation of Shc3 1 2 0.00 0.68 0.45
12 INT341211 Gopc Regulation of Shc1 1 2 0.02 0.68 0.45
13 INT168129 Binding of Yy1 and Positive_regulation of Transcription of Tln2 1 1 0.02 0 0.44
14 INT168132 Binding of Yy1 and Tln2 1 1 0.01 0 0.43
15 INT168134 Phosphorylation of Yy1 Negative_regulation of Binding of Yy1 and Tln2 1 1 0.02 0 0.43
16 INT251430 Gnat3 Positive_regulation of Gucy1b2 1 4 0.04 0.48 0.42
17 INT313455 Binding of Ppp2ca and Syp 1 5 0.45 0.68 0.4
18 INT322015 Binding of IL1B and P2RX7 1 1 0.07 1 0.37
19 INT251426 Gnat3 Negative_regulation of Aldh2 1 6 0.22 0 0.35
20 INT236006 HTR1A Regulation of Grin2b 1 1 0.00 0 0.33
21 INT322045 Gp6 Positive_regulation of Gene_expression of Selp 1 1 0.04 0.15 0.33
22 INT341215 Binding of Eif4e and Eif4g3 1 5 0.10 0.41 0.33
23 INT322016 Binding of IL1B and TLR4 1 1 0.05 0.18 0.32
24 INT341214 Tas2r130 Positive_regulation of Phosphorylation of Eif4ebp1 1 1 0.00 0.68 0.31
25 INT251388 Binding of Fbln2 and Gabbr1 1 3 0.08 0.07 0.3
26 INT101810 Binding of NFE2L2 and KEAP1 7 5 0.53 4.12 0.29
27 INT251420 Aldh3a1 Regulation of Gene_expression of Gnat3 1 1 0.09 0.08 0.28
28 INT313446 Syp Regulation of Ppp2ca 1 5 0.58 0.62 0.26
29 INT322021 Negative_regulation of CASP1 Positive_regulation of IL1B 1 1 0.04 0.13 0.26
30 INT236005 Positive_regulation of MAPK1 Positive_regulation of Binding of Map2 1 1 0.04 0 0.25
31 INT322018 CR1 Negative_regulation of IL1B 1 2 0.00 0.17 0.25
32 INT236004 Positive_regulation of MAPK1 Positive_regulation of Phosphorylation of Map2 1 1 0.04 0 0.24
33 INT188195 GOPC Positive_regulation of MAPK1 2 1 0.21 0.32 0.22
34 INT322011 BSG Regulation of P2RX7 1 1 0.00 0.48 0.21
35 INT322017 RPA1 Positive_regulation of IL1B 1 1 0.00 0 0.21
36 INT291788 ALDOA Positive_regulation of Gnat3 2 1 0.02 0.52 0.18
37 INT319663 Binding of Nfe2l2 and Keap1 1 11 0.40 2.83 0.17
38 INT313453 Siglec1 Regulation of Th 1 1 0.02 0.61 0.17
39 INT319680 Keap1 Negative_regulation of Positive_regulation of Nfe2l2 1 2 0.36 0.93 0.17
40 INT341213 Tas2r130 Positive_regulation of Gopc 1 1 0.00 0.2 0.17
41 INT313449 Siglec1 Regulation of Ppp2ca 1 1 0.03 0.61 0.17
42 INT168700 Positive_regulation of Binding of Nedd4 and Tyr 1 1 0.03 0.19 0.17
43 INT235984 HTR1A Negative_regulation of MAPK1 1 1 0.01 0 0.16
44 INT251435 Gnat3 Positive_regulation of NPR1 1 1 0.22 0.2 0.15
45 INT251424 Positive_regulation of Gnat3 Positive_regulation of Gucy1b2 1 1 0.02 0.2 0.15
46 INT251431 Negative_regulation of Gnat3 Positive_regulation of Gucy1b2 1 1 0.02 0.1 0.14
47 INT341222 Tas2r130 Positive_regulation of Positive_regulation of Gopc 1 1 0.00 0.2 0.14
48 INT313441 Th Regulation of Siglec1 1 1 0.02 0.22 0.13
49 INT322014 Binding of IRF6 and Positive_regulation of Localization of IL1B 1 1 0.01 0 0.13
50 INT313439 Syp Negative_regulation of Th 1 3 0.30 0.14 0.13
51 INT228453 Igf1 Positive_regulation of Prkca 2 1 0.12 1.17 0.12
52 INT341239 Binding of EIF4E and Eif4e 1 1 0.08 0.23 0.12
53 INT341238 Binding of EIF4E and Eif4g3 1 3 0.03 0.23 0.12
54 INT322037 Binding of P2RX7 and Myh1 1 2 0.06 0 0.12
55 INT313466 Syp Negative_regulation of Siglec1 1 1 0.05 0.24 0.12
56 INT313454 Negative_regulation of Syp Negative_regulation of Th 1 1 0.30 0.14 0.1
57 INT313308 Binding of SQSTM1 and KEAP1 1 9 0.46 1.16 0.1
58 INT322019 CASP8 Regulation of Gene_expression of IL1B 1 1 0.02 0 0.1
59 INT313301 SQSTM1 Regulation of Protein_catabolism of KEAP1 1 4 0.43 0.58 0.1
60 INT251389 Binding of Gabbr1 and Sds 1 1 0.23 0.32 0.1
61 INT319672 Nfe2l2 Regulation of Binding of Keap1 1 1 0.23 0.46 0.09
62 INT341235 Negative_regulation of INS Positive_regulation of Phosphorylation of Eif4ebp1 1 2 0.01 0.24 0.09
63 INT313430 Syp Positive_regulation of Ppp2ca 1 4 0.66 0.08 0.09
64 INT131598 Keap1 Negative_regulation of Nfe2l2 2 2 0.65 1.27 0.08
65 INT313442 Th Regulation of Phosphorylation of Syp 1 1 0.32 0 0.08
66 INT313447 Ppp2ca Regulation of Phosphorylation of Syp 1 1 0.43 0 0.08
67 INT313459 Gene_expression of Syp Negative_regulation of Th 1 2 0.30 0.49 0.08
68 INT313437 Th Regulation of Phosphorylation of Siglec1 1 1 0.04 0 0.08
69 INT322020 IL1B Regulation of Negative_regulation of CASP1 1 1 0.03 0 0.08
70 INT313469 Ppp2ca Regulation of Phosphorylation of Siglec1 1 1 0.06 0 0.08
71 INT339819 SRP72 Regulation of SRP54 1 1 0.38 0.37 0.08
72 INT319683 Binding of Jun and Nfe2l2 1 1 0.05 0.26 0.07
73 INT297210 Nfatc1 Regulation of Myoz1 1 1 0.06 0.51 0.07
74 INT322013 Negative_regulation of CR1 Negative_regulation of IL1B 1 1 0.00 0 0.06
75 INT313450 Th Regulation of Syp 1 2 0.32 0.6 0.06
76 INT341220 Eif4e Positive_regulation of Eif4ebp1 1 1 0.20 0.42 0.06
77 INT322002 CR1 Negative_regulation of IRF6 Positive_regulation of IL1B 1 1 0.00 0 0.06
78 INT297214 Myoz1 Regulation of Gene_expression of Car2 1 2 0.03 0.5 0.06
79 INT313463 Ppp2ca Regulation of Syp 1 2 0.43 0.6 0.06
80 INT341219 Binding of Eif4ebp1 and Eif4g3 1 1 0.05 0 0.06
81 INT339822 SRP68 Positive_regulation of SRP72 1 1 0.33 0.28 0.05
82 INT297211 Negative_regulation of Myoz1 Negative_regulation of Gene_expression of Car2 1 1 0.03 0.6 0.05
83 INT251427 Gnat3 Positive_regulation of Aldh2 1 1 0.26 0 0.05
84 INT333034 Trpv4 Positive_regulation of Localization of Car2 1 1 0.06 0 0.05
85 INT295866 Dss1 Positive_regulation of PSS 1 1 0.01 0.07 0.05
86 INT291749 ALDOA Regulation of ALDH2 1 1 0.04 0 0.05
87 INT291750 ALDOA Positive_regulation of ALDH2 1 1 0.08 0 0.05
88 INT169403 Binding of TRPV1 and Trpv4 1 1 0.23 0.94 0.05
89 INT251393 Gnat3 Positive_regulation of Gnat3 Negative_regulation of Aldh2 1 1 0.10 0 0.05
90 INT333032 Binding of Trpv4 and Gopc 1 2 0.05 0 0.04
91 INT291757 ALDOA Negative_regulation of Positive_regulation of SGCB 1 1 0.01 0 0.04
92 INT236009 HIST2H2AA3 Positive_regulation of Protein_catabolism of APP 1 1 0.02 0.19 0.04
93 INT236015 HIST2H2AA3 Positive_regulation of Gene_expression of APP 1 3 0.02 0.95 0.04
94 INT341231 INS Positive_regulation of Phosphorylation of Eif4ebp1 1 1 0.01 0.13 0.04
95 INT291782 Binding of ALDH2 and Gnat3 1 4 0.12 0 0.04
96 INT291751 ALDOA Positive_regulation of PON1 1 2 0.01 0 0.04
97 INT251425 Aldh2 Negative_regulation of Negative_regulation of Gnat3 1 1 0.19 0 0.04
98 INT291781 Regulation of Binding of ALDH2 and Gnat3 1 1 0.11 0 0.04
99 INT341236 ROS1 Positive_regulation of Phosphorylation of Eif4ebp1 1 1 0.02 0.25 0.04
100 INT291792 Regulation of Binding of ALDOA and Gnat3 1 1 0.02 0 0.04
101 INT295854 Srpk2 Regulation of Localization of Srsf1 1 1 0.21 0 0.04
102 INT313462 Syp Positive_regulation of Binding of Ppp2ca 1 1 0.47 0 0.04
103 INT291789 Binding of ALDOA and Gnat3 1 1 0.01 0 0.04
104 INT341241 Phosphorylation of Eif4ebp1 Positive_regulation of Binding of Eif4e and Eif4e 1 1 0.16 0.27 0.04
105 INT341237 ROS1 Negative_regulation of Ppp2r1a 1 2 0.01 0.31 0.04
106 INT313433 53T Regulation of Th 1 1 0.00 0 0.03
107 INT313464 Negative_regulation of Ppp2ca Positive_regulation of Phosphorylation of Mapk1 1 1 0.09 0 0.03
108 INT297207 Myoz1 Regulation of Gene_expression of Slc8a1 1 1 0.09 0.26 0.03
109 INT313445 53T Regulation of Ppp2ca 1 1 0.00 0 0.03
110 INT341225 Negative_regulation of Binding of Eif4e and Eif4ebp1 1 1 0.17 0.14 0.03
111 INT333037 Binding of Agt and Trpv4 1 2 0.09 0 0.03
112 INT295867 Srsf1 Regulation of VEGFA 1 1 0.10 0 0.03
113 INT313448 Gene_expression of Syp Positive_regulation of Th 1 1 0.28 0 0.03
114 INT291786 GOPC Negative_regulation of Gene_expression of Gnat3 1 1 0.01 0 0.03
115 INT313468 Negative_regulation of Syp Regulation of Th 1 1 0.30 0.3 0.03
116 INT291756 ALDH2 Positive_regulation of ALDOA 1 1 0.06 0 0.03
117 INT313451 Gene_expression of Syp Negative_regulation of Mapk1 1 1 0.09 0 0.03
118 INT197545 KEAP1 Regulation of NFE2L2 3 1 0.49 0.8 0
119 INT236016 ROS1 Positive_regulation of MAPK8 2 1 0.18 1.81 0
120 INT319686 Positive_regulation of Sfn Positive_regulation of Nfe2l2 1 1 0.18 0 0
121 INT319690 Gadd45gip1 Positive_regulation of Nfe2l2 1 1 0.45 0 0
122 INT295858 Prkca Positive_regulation of Gtf3a 1 1 0.00 0 0
123 INT319682 Binding of Nfe2l2 and Gadd45gip1 1 20 0.43 1.41 0
124 INT319657 Binding of Nfe2l2 and Gopc 1 3 0.10 0.17 0
125 INT313443 Syp Positive_regulation of Binding of Th 1 1 0.35 0.31 0
126 INT313305 SQSTM1 Regulation of NFE2L2 1 1 0.35 0.09 0
127 INT251419 Positive_regulation of Aldh2 Positive_regulation of Gnat3 1 1 0.20 0 0
128 INT319667 Gadd45gip1 Negative_regulation of Positive_regulation of Nfe2l2 1 1 0.53 0.06 0
129 INT295868 Igf1 Positive_regulation of VEGFA 1 1 0.16 0.19 0
130 INT341232 Binding of EIF4A2 and Eif4e 1 1 0.06 0 0
131 INT313461 Gopc Regulation of Th 1 1 0.07 0 0
132 INT291783 ALDOA Regulation of Gnat3 1 1 0.01 0 0
133 INT319668 Keap1 Regulation of Nfe2l2 1 5 0.52 0.84 0
134 INT291753 ALDOA Positive_regulation of ALDH1A1 1 1 0.00 0 0
135 INT313307 TERT Positive_regulation of NFE2L2 1 1 0.01 0 0
136 INT319693 Gene_expression of Gadd45gip1 Negative_regulation of Positive_regulation of Nfe2l2 1 1 0.39 0 0
137 INT313293 Binding of KEAP1 and GOPC 1 2 0.04 0.24 0
138 INT306677 Binding of Mapt and Atxn3 1 1 0.07 0.49 0
139 INT319673 Gadd45gip1 Regulation of Transcription of Nfe2l2 1 2 0.41 0.13 0
140 INT333035 Positive_regulation of Binding of Agt and Trpv4 1 1 0.11 0 0
141 INT313298 Negative_regulation of SQSTM1 Positive_regulation of KEAP1 1 1 0.39 0.39 0
142 INT319665 Binding of Gopc and Gadd45gip1 1 5 0.09 0.27 0
143 INT254745 Binding of Anxa3 and Skil 1 1 0.00 0 0
144 INT236013 HIST2H2AA3 Regulation of Gene_expression of APP 1 1 0.01 0 0
145 INT291787 Gnat3 Negative_regulation of ALDH2 1 1 0.11 0 0
146 INT251423 Gnat3 Regulation of Binding of Aldh3a1 1 1 0.09 0 0
147 INT291752 Binding of ALDH2 and SGCB 1 1 0.08 0 0
148 INT339800 P2RX1 Regulation of Negative_regulation of GOPC 1 1 0.04 0 0
149 INT291754 ALDOA Negative_regulation of ALDH2 1 1 0.07 0 0
150 INT319688 Gene_expression of Gadd45gip1 Positive_regulation of Positive_regulation of Ros1 1 1 0.03 0.23 0
151 INT295857 Igf1 Regulation of Localization of Srsf1 1 1 0.50 0 0
152 INT333030 Binding of Itch and Trpv4 1 5 0.14 0 0
153 INT313297 SQSTM1 Positive_regulation of Positive_regulation of NFE2L2 1 1 0.26 0 0
154 INT319687 Gadd45gip1 Negative_regulation of Nfe2l2 1 2 0.39 0.66 0
155 INT297209 Myoz1 Regulation of Mef2a 1 1 0.04 0.09 0
156 INT297212 Gene_expression of Ppp3ca Positive_regulation of Nfatc1 1 1 0.38 0.22 0
157 INT333046 Binding of Trpv4 and ITCH 1 1 0.39 0 0
158 INT313304 Binding of SQSTM1 and GOPC 1 1 0.04 0.24 0
159 INT319658 Jun Regulation of Gadd45gip1 1 1 0.07 0.13 0
160 INT313429 Syp Regulation of Phosphorylation of Siglec1 1 1 0.04 0.57 0
161 INT341240 Binding of EIF4E and Eif4ebp1 1 1 0.04 0.5 0
162 INT313457 Ppp2ca Regulation of Th 1 1 0.36 0 0
163 INT319666 Gadd45gip1 Regulation of Nfe2l2 1 15 0.55 2.23 0
164 INT339816 SRP72 Regulation of Binding of SRP72 and UCN2 1 1 0.16 0.08 0
165 INT319692 Binding of Keap1 and Gadd45gip1 1 2 0.35 0.18 0
166 INT333036 Trpv4 Positive_regulation of Gene_expression of Agt 1 1 0.12 0 0
167 INT339823 MAPK1 Negative_regulation of Gene_expression of SRP72 1 2 0.29 0.55 0
168 INT254747 Positive_regulation of Binding of Skil and Fig4 1 1 0.03 0.14 0
169 INT295869 Binding of VEGFA and Srsf1 1 2 0.17 0 0
170 INT319670 Negative_regulation of Binding of Nfe2l2 and Keap1 1 1 0.36 0.44 0
171 INT319678 Gadd45gip1 Regulation of Gopc 1 1 0.06 0 0
172 INT319681 Gadd45gip1 Regulation of Positive_regulation of Nfe2l2 1 2 0.41 0 0
173 INT297213 Myoz1 Regulation of Mef2c 1 1 0.02 0.09 0
174 INT313299 Negative_regulation of Binding of NFE2L2 and KEAP1 1 1 0.24 0.14 0
175 INT295870 Gene_expression of Srpk1 Negative_regulation of VEGFA 1 1 0.11 0 0
176 INT319671 Gadd45gip1 Regulation of Protein_catabolism of Nfe2l2 1 2 0.24 0.44 0
177 INT319660 Negative_regulation of Binding of Nfe2l2 and Gadd45gip1 1 1 0.39 0.11 0
178 INT319659 Sfn Positive_regulation of Nfe2l2 1 1 0.18 0 0
179 INT333033 Binding of Itch and Laptm5 1 1 0.01 0 0
180 INT341221 Eif4e Regulation of Binding of Eif4ebp1 1 1 0.18 0 0
181 INT319662 Gadd45gip1 Negative_regulation of Keap1 1 1 0.42 0.66 0
182 INT319691 Binding of Gadd45gip1 and Regulation of Nfe2l2 1 1 0.24 0.23 0
183 INT341227 Mtor Regulation of Phosphorylation of Eif4ebp1 1 1 0.02 0.19 0
184 INT236014 HIST2H2AA3 Positive_regulation of MAPK8 1 2 0.02 0.44 0
185 INT319694 Jun Regulation of Gadd45gip1 Negative_regulation of Gopc 1 1 0.02 0.13 0
186 INT251418 Gnat3 Regulation of Aldh2 1 1 0.12 0 0
187 INT313465 Syp Regulation of Regulation of Ppp2ca 1 1 0.26 0.56 0
188 INT297208 Myoz1 Regulation of Dnm1l 1 2 0.05 0.17 0
189 INT236011 HIST2H2AA3 Positive_regulation of MAPK1 1 1 0.00 0.17 0
190 INT313426 Positive_regulation of Ppp2ca Positive_regulation of Bax 1 1 0.46 0.36 0
191 INT295856 Binding of Prkca and Srsf1 1 1 0.10 0 0
192 INT236017 GOPC Positive_regulation of MAPK8 1 1 0.09 0.17 0
193 INT319656 Gadd45gip1 Regulation of Gene_expression of Nfe2l2 1 4 0.55 0.89 0
194 INT295855 Prkca Positive_regulation of Akt1 1 1 0.02 0 0
195 INT313296 Binding of KEAP1 and PGAM5 1 1 0.11 0.15 0
196 INT319661 Binding of Stat3 and Gadd45gip1 1 1 0.20 0.17 0
197 INT291780 Gnat3 Positive_regulation of Gnat3 Negative_regulation of ALDH2 1 1 0.03 0 0
198 INT319677 Binding of Elf3 and Gadd45gip1 1 1 0.13 0.17 0
199 INT341234 Eif4g3 Positive_regulation of Binding of EIF4E 1 1 0.04 0 0
200 INT341216 Regulation of Binding of Eif4e and Eif4ebp1 1 1 0.11 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT18357 Gene_expression of TRPV1 33 825 0.78 307.11 382.81
2 INT10832 Gene_expression of IL8 1 1050 0.78 698.72 270
3 INT5972 Gene_expression of IL1B 23 948 0.78 510.91 263.97
4 INT68684 Gene_expression of VEGFA 10 2371 0.78 1742.52 259.2
5 INT2391 Negative_regulation of PTGS1 1 501 0.59 207.62 205.6
6 INT63934 Phosphorylation of Ephb1 3 377 0.82 150.52 188.66
7 INT24326 Gene_expression of Ngf 2 346 0.78 218.67 184.71
8 INT120811 Gene_expression of Gopc 21 1174 0.59 428.49 150.55
9 INT49134 Gene_expression of Grin1 3 270 0.78 84.78 148.61
10 INT5116 Gene_expression of IL2 1 670 0.78 291.13 146.69
11 INT64161 Positive_regulation of Prkca 5 213 0.70 85.06 129.91
12 INT65600 Positive_regulation of Casp3 2 376 0.70 198.44 128.03
13 INT5931 Regulation of Oprm1 2 149 0.62 18.15 125.93
14 INT85640 Gene_expression of Tg(CAG-EGFP)D4Nagy 7 1138 0.72 311.58 119.18
15 INT170025 Gene_expression of Fig4 3 588 0.67 183.27 113.32
16 INT69440 Gene_expression of ROS1 7 752 0.78 477.64 103.83
17 INT90091 Gene_expression of GOPC 8 967 0.67 366.22 103.6
18 INT11381 Positive_regulation of IL1B 31 330 0.70 209.31 100.9
19 INT65500 Gene_expression of App 3 605 0.78 429.94 98.31
20 INT1760 Gene_expression of PTGER2 1 524 0.57 226.94 96.4
21 INT3537 Positive_regulation of Car2 4 413 0.56 103.51 94.35
22 INT9516 Negative_regulation of Gabrg1 1 149 0.53 27.83 91.02
23 INT71789 Positive_regulation of MAPK1 9 396 0.70 234.44 89.27
24 INT96917 Positive_regulation of Mapk14 2 261 0.70 173.29 88.79
25 INT64158 Negative_regulation of Prkca 20 121 0.59 29.8 88.66
26 INT7180 Negative_regulation of Trib3 1 180 0.51 68.48 88.01
27 INT92434 Phosphorylation of Mapk1 1 287 0.82 91.65 83.46
28 INT92434 Phosphorylation of Mapk1 3 287 0.82 91.65 83.46
29 INT68682 Positive_regulation of VEGFA 3 640 0.70 454.14 81.65
30 INT3214 Localization of Ins1 1 527 0.80 196.9 79.26
31 INT12476 Negative_regulation of TRPV1 8 124 0.59 47.95 77.98
32 INT9382 Regulation of TRPV1 13 149 0.62 53.99 77.46
33 INT79506 Gene_expression of Grin2b 2 122 0.78 43.71 73.42
34 INT63936 Positive_regulation of Phosphorylation of Ephb1 3 131 0.70 49.38 73.16
35 INT11380 Negative_regulation of IL1B 4 215 0.59 125.62 72.35
36 INT10837 Positive_regulation of Gene_expression of IL8 1 294 0.70 190.08 70.34
37 INT79494 Positive_regulation of Gene_expression of VEGFA 4 577 0.70 442.94 69.73
38 INT6849 Localization of IL1B 32 229 0.81 112.56 69.63
39 INT24989 Positive_regulation of Cfp 1 125 0.61 29.55 64.9
40 INT2761 Regulation of Gabrg1 2 119 0.61 18.8 60.52
41 INT17564 Gene_expression of Gpt 1 322 0.75 208.51 60.36
42 INT103924 Positive_regulation of Akt1 3 359 0.69 158.94 60.34
43 INT62960 Gene_expression of P2rx2 8 149 0.77 58.31 59.16
44 INT169926 Positive_regulation of Gopc 9 416 0.46 157.8 58.67
45 INT7340 Regulation of Grin1 8 87 0.62 30.37 57.93
46 INT31116 Gene_expression of Casp3 5 192 0.78 78.21 57.43
47 INT64159 Gene_expression of Prkca 7 90 0.78 34.65 55.97
48 INT49436 Binding of TRPV1 14 145 0.48 38.35 55.08
49 INT96914 Phosphorylation of Mapk14 2 168 0.82 108.46 53.32
50 INT4957 Negative_regulation of Grin1 5 87 0.59 24.51 53.21
51 INT6034 Binding of Gabrg1 2 115 0.47 17.48 51.92
52 INT6473 Positive_regulation of Gene_expression of IL1B 6 204 0.70 117.23 50.86
53 INT106525 Phosphorylation of Akt1 5 436 0.82 183.81 47.82
54 INT170646 Negative_regulation of Fig4 1 213 0.37 81.29 46.92
55 INT30170 Gene_expression of Car2 11 330 0.66 77.26 46.76
56 INT71786 Phosphorylation of MAPK1 1 256 0.82 110.09 46.17
57 INT80124 Negative_regulation of VEGFA 2 450 0.58 311.19 44.53
58 INT17561 Localization of Car2 9 303 0.79 60.95 44.52
59 INT25383 Gene_expression of Csf2 2 222 0.76 152.93 43.32
60 INT157666 Positive_regulation of GOPC 4 335 0.60 120.19 42.75
61 INT170054 Negative_regulation of Gopc 7 280 0.38 117.89 42.4
62 INT9233 Negative_regulation of Gene_expression of IL1B 1 114 0.59 56.99 41.82
63 INT57442 Phosphorylation of Prkca 2 98 0.70 31.58 41.04
64 INT69437 Positive_regulation of ROS1 3 328 0.58 222.83 40.56
65 INT92437 Positive_regulation of Phosphorylation of Mapk1 1 113 0.70 32.19 40.29
66 INT92437 Positive_regulation of Phosphorylation of Mapk1 1 113 0.70 32.19 40.29
67 INT5973 Regulation of IL1B 8 109 0.62 66.6 39.88
68 INT3252 Negative_regulation of INS 3 428 0.59 271.65 39.52
69 INT173693 Localization of Gopc 4 249 0.65 70.49 38.81
70 INT43507 Gene_expression of Gabbr1 16 79 0.78 28.53 38.22
71 INT30817 Gene_expression of Th 17 142 0.76 33.56 38.12
72 INT77307 Gene_expression of Bcl2 1 399 0.77 319.77 38
73 INT80690 Positive_regulation of MAPK8 14 223 0.68 125.63 36.75
74 INT17736 Gene_expression of Cfp 5 111 0.65 40.68 36.61
75 INT133028 Gene_expression of TLR2 1 209 0.73 131.92 36.17
76 INT64436 Gene_expression of P2rx1 1 93 0.78 32.69 36.12
77 INT60710 Gene_expression of Col7a1 1 217 0.78 113.2 35.2
78 INT6484 Binding of IL1B 4 122 0.47 75.84 35.07
79 INT12161 Positive_regulation of P2rx2 1 70 0.69 34.22 34.4
80 INT14559 Gene_expression of Igf1 2 254 0.78 112 34.17
81 INT17381 Gene_expression of Tbxa2r 1 146 0.78 65.01 34.15
82 INT74563 Positive_regulation of Gene_expression of ROS1 3 258 0.61 168.18 34.08
83 INT109820 Gene_expression of Trpv4 10 121 0.78 39.69 33.11
84 INT234 Binding of Alb 8 151 0.48 52.34 32.97
85 INT57024 Regulation of Gene_expression of Grin1 1 32 0.62 9.77 32.6
86 INT73982 Gene_expression of Hmox1 2 141 0.78 119.43 32.17
87 INT114881 Gene_expression of Akt1 1 227 0.78 102.49 31.81
88 INT48693 Regulation of VEGFA 4 268 0.62 191.88 31.52
89 INT86780 Positive_regulation of Hmox1 1 145 0.70 117.09 31.18
90 INT117112 Negative_regulation of Mapk1 1 87 0.56 40.34 31.18
91 INT99688 Negative_regulation of Gene_expression of VEGFA 2 274 0.58 201.8 31.1
92 INT64164 Regulation of Prkca 2 34 0.62 10.44 30.99
93 INT15610 Localization of GOPC 7 223 0.65 68.26 28.7
94 INT93033 Negative_regulation of Grin2b 6 48 0.58 20.94 28.54
95 INT83708 Negative_regulation of MAPK1 16 156 0.57 84.93 27.85
96 INT22045 Gene_expression of IRF6 5 158 0.75 58.07 27.81
97 INT177581 Regulation of Fig4 1 113 0.41 39.26 27.75
98 INT64499 Positive_regulation of IRF6 3 123 0.49 52.73 27.51
99 INT145426 Positive_regulation of Ros1 4 185 0.56 106.76 27.21
100 INT1765 Positive_regulation of Gene_expression of PTGER2 1 140 0.51 68.68 27
101 INT95481 Regulation of Gene_expression of TRPV1 2 48 0.62 29.3 26.28
102 INT1761 Positive_regulation of PTGER2 1 135 0.49 90.17 26.26
103 INT86789 Gene_expression of P2rx4 2 46 0.77 30.66 25.68
104 INT89662 Positive_regulation of Gene_expression of App 1 169 0.70 133.36 25.62
105 INT12124 Gene_expression of MAPK1 3 141 0.75 82.4 25.58
106 INT172458 Regulation of Gopc 4 155 0.53 62.57 24.86
107 INT49141 Gene_expression of Selp 5 157 0.78 85.22 24.78
108 INT14556 Positive_regulation of Igf1 3 105 0.69 52.21 24.04
109 INT44954 Gene_expression of APP 20 191 0.78 105.86 23.9
110 INT63419 Gene_expression of PTGES 7 109 0.77 40.83 23.67
111 INT17962 Regulation of Car2 3 124 0.41 33.98 22.71
112 INT23564 Negative_regulation of Car2 2 103 0.50 27.28 21.86
113 INT5916 Positive_regulation of HTR1A 4 51 0.67 18.27 21.38
114 INT48692 Binding of VEGFA 3 345 0.48 210.3 21.31
115 INT117527 Binding of Prkca 1 25 0.48 6.43 21.05
116 INT97798 Localization of IRF6 4 86 0.73 33.27 20.94
117 INT170444 Binding of Gopc 6 172 0.39 45.05 20.71
118 INT105021 Binding of GOPC 3 187 0.40 60.39 20.38
119 INT24240 Positive_regulation of Th 13 60 0.70 9.92 20.18
120 INT111401 Positive_regulation of Gene_expression of Tg(CAG-EGFP)D4Nagy 2 134 0.61 34.87 20.15
121 INT16794 Binding of App 1 103 0.48 64.87 19.79
122 INT78694 Positive_regulation of Gene_expression of Casp3 3 46 0.66 18.64 19.62
123 INT6993 Negative_regulation of Mpo 1 72 0.59 61.83 19.51
124 INT86187 Positive_regulation of AKT1 1 199 0.69 122.13 19.44
125 INT91916 Gene_expression of P2rx3 1 51 0.78 21.2 19.05
126 INT91462 Positive_regulation of Phosphorylation of MAPK1 1 99 0.67 40.28 18.99
127 INT80223 Positive_regulation of Hmox1 4 128 0.68 77.71 17.64
128 INT116950 Negative_regulation of MAPK8 4 103 0.57 44.48 17.53
129 INT36054 Transcription of IL1B 1 53 0.72 32.64 17.31
130 INT119233 Positive_regulation of Trpv4 10 65 0.70 20.21 17.3
131 INT219 Negative_regulation of Th 13 55 0.59 20.88 17.09
132 INT68681 Transcription of VEGFA 1 132 0.71 80.47 17.03
133 INT170051 Positive_regulation of Gene_expression of Gopc 6 150 0.43 56.75 16.93
134 INT23657 Positive_regulation of APP 1 64 0.70 39.76 16.68
135 INT59365 Gene_expression of HTR1A 3 41 0.75 16.31 16.57
136 INT109929 Phosphorylation of MAPK8 6 102 0.81 39.98 16.54
137 INT197375 Gene_expression of Car1 1 84 0.65 16.46 16.45
138 INT78697 Negative_regulation of Gene_expression of Casp3 2 33 0.57 11.22 16.16
139 INT24241 Phosphorylation of Th 40 35 0.81 8.69 16.06
140 INT14152 Gene_expression of Slc17a5 1 46 0.61 20.01 15.9
141 INT79458 Localization of Prkca 3 30 0.81 11.13 15.78
142 INT97245 Gene_expression of AKT1 2 217 0.77 119.63 15.59
143 INT111462 Negative_regulation of Phosphorylation of Mapk1 1 45 0.57 19.49 15.59
144 INT91285 Negative_regulation of P2rx2 1 29 0.57 12.74 15.48
145 INT171666 Regulation of GOPC 2 117 0.39 40.41 15.47
146 INT75531 Regulation of MAPK1 4 70 0.61 34.39 15.42
147 INT170855 Negative_regulation of GOPC 7 188 0.38 70.92 15.41
148 INT92839 Regulation of P2rx2 2 36 0.45 13.19 15.38
149 INT109535 Gene_expression of Vegfa 1 116 0.75 84.61 14.89
150 INT127046 Gene_expression of P2RX7 5 65 0.78 34.28 14.76
151 INT14131 Regulation of HTR1A 9 34 0.60 9.61 14.74
152 INT66611 Localization of Cfp 1 22 0.65 7.04 14.64
153 INT65263 Positive_regulation of Gene_expression of Igf1 2 61 0.69 25.69 14.49
154 INT25266 Positive_regulation of Localization of IL1B 8 38 0.69 15.89 14.35
155 INT80688 Positive_regulation of Positive_regulation of MAPK1 1 72 0.69 39.35 14.11
156 INT80228 Positive_regulation of Gene_expression of Hmox1 2 68 0.70 62.88 14.01
157 INT17565 Regulation of Gpt 1 85 0.60 43.64 13.68
158 INT19191 Negative_regulation of Localization of IL1B 1 35 0.58 15.19 13.63
159 INT91703 Negative_regulation of Myoz1 6 78 0.58 53.78 13.5
160 INT80685 Gene_expression of MAPK8 11 90 0.72 51.91 13.36
161 INT76469 Positive_regulation of Gene_expression of Prkca 2 18 0.46 7.9 13.36
162 INT26545 Gene_expression of Hras1 1 173 0.78 79.54 13.21
163 INT99586 Binding of IRF6 2 60 0.36 27.87 13.2
164 INT174844 Binding of Fig4 7 81 0.41 18.03 12.87
165 INT116528 Gene_expression of HMOX1 1 106 0.78 86.13 12.8
166 INT122117 Negative_regulation of Gene_expression of Grin2b 1 20 0.59 11.3 12.55
167 INT89395 Negative_regulation of AKT1 1 127 0.58 70.27 12.54
168 INT31990 Positive_regulation of SOD1 1 124 0.69 67.79 12.52
169 INT107033 Gene_expression of Slc37a4 1 66 0.62 27.34 12.35
170 INT91413 Negative_regulation of PTGES 14 35 0.58 17.94 12.03
171 INT91413 Negative_regulation of PTGES 3 35 0.58 17.94 12.03
172 INT170601 Positive_regulation of Gene_expression of GOPC 1 122 0.43 42.79 11.68
173 INT14132 Negative_regulation of HTR1A 4 25 0.57 4.93 10.91
174 INT86729 Positive_regulation of CDCP1 1 37 0.07 18.74 10.76
175 INT78567 Positive_regulation of Gene_expression of Th 5 25 0.68 5.32 10.75
176 INT133030 Positive_regulation of Gene_expression of TLR2 1 53 0.65 38.15 10.65
177 INT118390 Positive_regulation of Nfe2l2 13 82 0.70 20.41 10.61
178 INT104441 Binding of NOVA2 1 72 0.42 16.41 10.51
179 INT5476 Regulation of Gabbr1 3 21 0.45 4.01 10.26
180 INT27955 Negative_regulation of Gene_expression of Ngf 1 16 0.59 10.43 10.17
181 INT134625 Gene_expression of Kdr 1 116 0.71 53.13 10.09
182 INT137980 Positive_regulation of P2RX7 14 30 0.67 22.49 10
183 INT102865 Positive_regulation of Positive_regulation of Prkca 1 25 0.69 8.34 9.9
184 INT6356 Binding of Gabbr1 6 30 0.48 4.62 9.82
185 INT178306 Negative_regulation of Gene_expression of Gopc 2 71 0.37 26.43 9.74
186 INT75137 Regulation of Akt1 1 74 0.48 37.89 9.7
187 INT4808 Gene_expression of LTC4S 1 37 0.73 18.36 9.62
188 INT62919 Regulation of Gnas 1 22 0.43 5.61 9.55
189 INT41569 Regulation of APP 1 32 0.62 17.15 9.4
190 INT71174 Gene_expression of CASP1 1 44 0.75 30.3 9.37
191 INT129585 Gene_expression of St13 2 17 0.59 4.46 9.3
192 INT21846 Localization of Spna1 1 27 0.78 5.14 9.22
193 INT1129 Binding of Car2 1 69 0.35 14.01 9.2
194 INT42971 Binding of Hivep3 1 14 0.42 3.92 8.99
195 INT3755 Positive_regulation of GBE1 1 29 0.40 8.99 8.91
196 INT47769 Phosphorylation of Fos 1 20 0.61 3.03 8.68
197 INT170504 Positive_regulation of Gene_expression of Car2 2 60 0.41 19.1 8.45
198 INT6352 Negative_regulation of Gabbr1 2 7 0.59 4.84 7.93
199 INT175526 Phosphorylation of Gopc 4 73 0.53 21.08 7.86
200 INT106522 Negative_regulation of Phosphorylation of Akt1 1 65 0.58 34.44 7.83
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