J:The Open Dentistry Journal

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT86179 TNF Positive_regulation of Localization of IL6 5 1 0.35 1.66 2.17
2 INT292893 TNF Regulation of IL8 2 1 0.27 1.3 0.63
3 INT267585 TNF Regulation of IL6 2 1 0.16 2.44 0.37
4 INT311264 IL6 Positive_regulation of Gene_expression of PPIAP10 1 1 0.30 0.98 0.36
5 INT311265 RENBP Regulation of IL8 1 2 0.03 1.59 0.33
6 INT311263 RENBP Regulation of TNF 1 2 0.01 1.59 0.33
7 INT311266 RENBP Regulation of IL6 1 2 0.02 1.59 0.32
8 INT311268 RENBP Regulation of Gene_expression of IL8 1 1 0.02 1.05 0.24
9 INT311262 RENBP Regulation of Regulation of TNF 1 1 0.02 0.33 0.13
10 INT311267 RENBP Regulation of Gene_expression of TNF 1 1 0.02 0.54 0.09
11 INT269508 Binding of HTN1 and CFP 1 2 0.00 0 0.08
12 INT269510 Binding of HTN1 and fc 1 2 0.00 0 0.07
13 INT269509 Binding of CFP and fc 1 1 0.00 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 7 3152 0.78 2515.62 929.82
2 INT9238 Gene_expression of IL6 5 1575 0.78 1135.66 424.22
3 INT5059 Positive_regulation of TNF 1 1050 0.70 896.51 322.81
4 INT6852 Localization of TNF 1 883 0.81 705.95 270.84
5 INT10832 Gene_expression of IL8 7 1050 0.78 698.72 270
6 INT9659 Gene_expression of Il6 1 991 0.78 715.11 265.57
7 INT5972 Gene_expression of IL1B 4 948 0.78 510.91 263.97
8 INT6481 Binding of TNF 2 624 0.48 510.2 214.82
9 INT11313 Positive_regulation of Il6 1 526 0.70 331.27 201.59
10 INT10194 Positive_regulation of IL6 1 702 0.70 600.62 183.38
11 INT15516 Gene_expression of Crp 2 711 0.77 615.33 173.09
12 INT66280 Gene_expression of Nos2 1 534 0.78 330.78 157.07
13 INT9660 Regulation of TNF 1 363 0.62 312.94 139.99
14 INT48895 Gene_expression of Il10 7 333 0.78 221.2 138.52
15 INT8243 Positive_regulation of Il6 1 451 0.70 358.24 119.28
16 INT50674 Gene_expression of PTGS2 3 459 0.78 253.33 118.51
17 INT12339 Localization of IL8 1 437 0.81 251.87 117.39
18 INT62124 Gene_expression of NOS1 2 444 0.78 218.08 114.85
19 INT48593 Positive_regulation of NOS1 1 420 0.68 226.15 114.71
20 INT12082 Localization of IL6 5 365 0.81 241.78 105.78
21 INT90091 Gene_expression of GOPC 4 967 0.67 366.22 103.6
22 INT11381 Positive_regulation of IL1B 2 330 0.70 209.31 100.9
23 INT11380 Negative_regulation of IL1B 1 215 0.59 125.62 72.35
24 INT10837 Positive_regulation of Gene_expression of IL8 1 294 0.70 190.08 70.34
25 INT15514 Negative_regulation of Crp 1 275 0.59 194.6 64.86
26 INT822 Gene_expression of ESR1 1 529 0.78 302.16 63.64
27 INT9657 Positive_regulation of Gene_expression of Il6 1 237 0.70 180.45 63.6
28 INT39153 Positive_regulation of PTGS2 1 182 0.70 96.16 60.6
29 INT9196 Gene_expression of PTGS1 2 215 0.77 96.99 60.5
30 INT55344 Gene_expression of Ros1 2 396 0.54 217.64 59.98
31 INT6477 Gene_expression of IL1RN 1 213 0.77 114.69 58.62
32 INT48901 Negative_regulation of IL6 1 186 0.57 136.33 57.87
33 INT48891 Positive_regulation of Il10 1 143 0.70 101.42 56.72
34 INT1200 Negative_regulation of Ins1 1 274 0.58 155.17 56.14
35 INT52692 Gene_expression of Ptgs2 1 160 0.78 85.06 55.73
36 INT6473 Positive_regulation of Gene_expression of IL1B 1 204 0.70 117.23 50.86
37 INT9094 Gene_expression of COL7A1 2 277 0.77 143.42 38.73
38 INT68975 Gene_expression of Mmp9 1 111 0.78 79.57 38.55
39 INT65889 Gene_expression of RETNLB 1 73 0.34 60.98 38.3
40 INT9082 Positive_regulation of ESR1 1 238 0.69 148.51 36.69
41 INT48896 Positive_regulation of Gene_expression of Il10 2 73 0.70 43.14 35.5
42 INT6484 Binding of IL1B 1 122 0.47 75.84 35.07
43 INT79060 Gene_expression of NOS2 1 116 0.78 69.25 34.84
44 INT9655 Regulation of Il6 1 98 0.62 70.92 31.95
45 INT64113 Positive_regulation of Gene_expression of NOS1 1 110 0.60 71.03 29.72
46 INT28361 Gene_expression of TP53 2 443 0.78 384.86 28.8
47 INT15610 Localization of GOPC 2 223 0.65 68.26 28.7
48 INT703 Positive_regulation of Pth 2 177 0.70 127.09 27.26
49 INT17739 Gene_expression of S100B 1 226 0.78 132.7 26.4
50 INT68758 Positive_regulation of Ros1 1 125 0.46 82.72 25.27
51 INT10836 Negative_regulation of IL8 4 95 0.59 52.59 24.71
52 INT79061 Positive_regulation of NOS2 1 92 0.65 58.89 23.96
53 INT63419 Gene_expression of PTGES 2 109 0.77 40.83 23.67
54 INT5905 Negative_regulation of ELANE 2 113 0.59 47.43 22.09
55 INT52693 Positive_regulation of Gene_expression of Ptgs2 1 57 0.70 25.51 21.18
56 INT72060 Positive_regulation of Gene_expression of Ros1 1 127 0.41 76.76 20.91
57 INT105021 Binding of GOPC 1 187 0.40 60.39 20.38
58 INT74286 Regulation of Il10 1 42 0.44 28.06 19.44
59 INT16445 Gene_expression of IL1A 3 60 0.78 44.46 19.19
60 INT2006 Gene_expression of fc 1 104 0.34 64.91 19.08
61 INT56749 Gene_expression of PCNA 7 219 0.77 111.25 18.42
62 INT65856 Positive_regulation of TP53 1 138 0.67 112.65 16.71
63 INT10834 Binding of IL8 1 65 0.48 41.66 16.53
64 INT10214 Gene_expression of VIM 1 153 0.78 115.88 16.29
65 INT180497 Binding of MRI1 1 45 0.42 28.35 14.77
66 INT39507 Positive_regulation of TXNRD1 1 37 0.68 12.47 14.25
67 INT70265 Regulation of MRI1 1 42 0.39 30.95 14.18
68 INT2673 Negative_regulation of PROC 1 93 0.57 50.34 12.79
69 INT55343 Localization of Ros1 1 39 0.60 34.51 12.5
70 INT12135 Gene_expression of PLEK 1 62 0.75 34.13 12.47
71 INT79545 Positive_regulation of Gene_expression of ESR1 1 82 0.64 39.42 12.18
72 INT8629 Positive_regulation of COL7A1 1 72 0.69 40.66 12.09
73 INT4047 Binding of F13A1 2 105 0.43 66.54 11.81
74 INT95632 Positive_regulation of MMP8 1 26 0.70 10.06 9.96
75 INT125247 Negative_regulation of Mmp9 1 42 0.43 23.68 9.37
76 INT55342 Negative_regulation of Gene_expression of Ros1 1 49 0.37 31.62 8.93
77 INT92822 Negative_regulation of Gene_expression of Crp 1 36 0.49 29.5 8.83
78 INT59165 Binding of fc 1 67 0.36 37.51 8.68
79 INT19475 Positive_regulation of IL1A 1 20 0.67 17.99 7.57
80 INT103289 Binding of Il10 1 15 0.35 13.67 7.42
81 INT91906 Regulation of Gene_expression of Il10 1 13 0.58 8.92 7.06
82 INT7205 Positive_regulation of HBG1 1 65 0.69 40.35 6.37
83 INT91159 Negative_regulation of Ros1 1 35 0.44 26.12 5.97
84 INT87468 Negative_regulation of Mmp2 1 24 0.57 10.79 5.55
85 INT12104 Positive_regulation of PLG 1 45 0.68 28.94 4.81
86 INT8773 Gene_expression of HBG1 1 58 0.76 37.6 4.59
87 INT59083 Positive_regulation of Gene_expression of IL1A 2 11 0.70 9.09 4.48
88 INT125896 Negative_regulation of Gene_expression of Mmp9 1 15 0.43 13.73 4.18
89 INT76227 Binding of NPC1 1 30 0.41 32.31 4.05
90 INT7437 Gene_expression of CFP 1 21 0.65 4.93 3.89
91 INT137702 Binding of TTN 1 7 0.35 4.48 3.62
92 INT17685 Negative_regulation of Cog1 1 23 0.42 15.65 3.56
93 INT307700 Regulation of HOPX 7 4 0.53 7.64 3.5
94 INT79270 Gene_expression of MKI67 2 113 0.77 63.52 3.38
95 INT102741 Gene_expression of Atp9b 4 20 0.75 8.01 3.34
96 INT27918 Positive_regulation of Klk1c7 1 6 0.36 2.89 2.84
97 INT104474 Gene_expression of Mmp8 1 15 0.71 3.1 2.76
98 INT57957 Localization of TXNRD1 1 14 0.64 4.01 2.7
99 INT174687 Regulation of Positive_regulation of Il6 1 10 0.61 9.07 2.61
100 INT55952 Transcription of TP53 1 16 0.61 12.14 2.36
101 INT116516 Positive_regulation of GCFC2 5 5 0.49 2.83 2.17
102 INT156093 Negative_regulation of Positive_regulation of Ros1 1 8 0.23 5.17 2.03
103 INT35146 Negative_regulation of PLG 3 27 0.57 17.63 1.98
104 INT59876 Regulation of fc 2 10 0.14 3.66 1.82
105 INT68952 Localization of PCNA 1 17 0.62 5.64 1.78
106 INT74586 Negative_regulation of MMP8 2 6 0.27 1.68 1.64
107 INT91664 Positive_regulation of Negative_regulation of IL8 1 5 0.40 3.28 1.62
108 INT65684 Gene_expression of MDM2 2 30 0.62 24.94 1.55
109 INT18114 Gene_expression of NPC1 1 45 0.66 57.85 1.44
110 INT60571 Positive_regulation of Gsta4 1 8 0.45 3.76 1.44
111 INT70615 Binding of TXNRD1 1 25 0.36 12.15 1.27
112 INT158542 Gene_expression of HTN1 1 10 0.75 10.69 1.07
113 INT355175 Gene_expression of HOPX 3 1 0.58 1.67 1.01
114 INT89128 Binding of DSPP 3 7 0.32 2.24 0.98
115 INT71916 Gene_expression of TTN 1 9 0.75 1.69 0.97
116 INT8772 Positive_regulation of Gene_expression of HBG1 1 16 0.68 6.93 0.95
117 INT79169 Binding of PLG 1 10 0.47 5.88 0.72
118 INT22096 Negative_regulation of SOS1 1 4 0.25 1.63 0.71
119 INT110806 Positive_regulation of Mmp8 1 7 0.46 1.64 0.67
120 INT81075 Negative_regulation of Atp9b 1 7 0.57 1.39 0.64
121 INT231950 Gene_expression of Myh1 24 31 0.69 3.7 0.51
122 INT176264 Binding of PCNA 1 21 0.21 9.08 0.51
123 INT178834 Localization of MR1 1 8 0.21 6.52 0.48
124 INT231954 Positive_regulation of Gene_expression of Myh1 3 6 0.45 1.28 0.48
125 INT153758 Binding of Mitf 1 5 0.47 2.5 0.46
126 INT235200 Positive_regulation of Negative_regulation of ELANE 1 3 0.38 1.68 0.46
127 INT178830 Negative_regulation of MR1 1 16 0.50 7.63 0.44
128 INT78592 Positive_regulation of Atp9b 2 4 0.49 1.54 0.44
129 INT156997 Localization of NPC1 1 19 0.64 30 0.42
130 INT42032 Localization of PNLIP 1 4 0.14 3.44 0.41
131 INT132853 Gene_expression of GCFC2 3 2 0.58 1.06 0.41
132 INT97450 Gene_expression of Mitf 2 36 0.75 17.22 0.39
133 INT211361 Regulation of RENBP 1 5 0.08 2.8 0.38
134 INT233007 Negative_regulation of VIM 1 6 0.41 3.46 0.36
135 INT277252 Gene_expression of PPIAP10 1 2 0.75 1.31 0.35
136 INT75504 Gene_expression of CDK4 2 9 0.72 7.43 0.3
137 INT311269 Positive_regulation of Positive_regulation of GCFC2 2 1 0.21 0.83 0.3
138 INT48254 Negative_regulation of Klk1c8 1 3 0.13 2.09 0.29
139 INT231952 Positive_regulation of Myh1 9 14 0.62 0.82 0.27
140 INT251897 Negative_regulation of Gene_expression of Mmp8 1 1 0.04 0.96 0.27
141 INT251907 Negative_regulation of Positive_regulation of MMP8 1 1 0.00 1.23 0.26
142 INT278596 Localization of BOP 3 1 0.45 1.15 0.24
143 INT300326 Transcription of Atp9b 6 7 0.12 0.39 0.2
144 INT129762 Binding of HTN1 2 5 0.03 5.68 0.19
145 INT278594 Binding of BOP 4 5 0.29 2.01 0.17
146 INT172924 Gene_expression of BOP 5 8 0.47 3.15 0.14
147 INT251898 Negative_regulation of Transcription of Gsta4 1 1 0.08 1.04 0.11
148 INT251899 Transcription of Gsta4 1 1 0.10 1.04 0.1
149 INT355176 Regulation of Binding of TTN 1 1 0.29 0.78 0.09
150 INT274685 Localization of PROK2 2 3 0.42 0.31 0.08
151 INT251894 Regulation of Regulation of Lama5 1 1 0.01 1.07 0.08
152 INT251895 Regulation of Lama5 1 1 0.01 1.06 0.08
153 INT274686 Phosphorylation of PNLIP 2 1 0.04 0.18 0.08
154 INT141083 Transcription of Myh1 31 32 0.64 1.23 0.06
155 INT278595 Regulation of Binding of BOP 1 1 0.27 0.33 0.05
156 INT274684 Phosphorylation of HIST2H4A 2 1 0.12 0.18 0.05
157 INT274687 Phosphorylation of PROK2 2 1 0.06 0.17 0.05
158 INT174145 Positive_regulation of EBM 1 5 0.44 0.49 0.04
159 INT300333 Negative_regulation of Myh1 4 5 0.52 0.66 0.04
160 INT272429 Positive_regulation of PROK2 1 2 0.32 0.24 0.03
161 INT251896 Negative_regulation of Lama5 1 1 0.01 0.82 0.03
162 INT278590 Gene_expression of Eci1 1 1 0.07 0.39 0.03
163 INT274683 Localization of HIST2H4A 3 5 0.12 1.54 0
164 INT250698 Positive_regulation of Transcription of TP53 1 3 0.18 3.68 0
165 INT192805 Binding of PTMS 1 2 0.36 0.65 0
166 INT174144 Regulation of EBM 2 2 0.24 0.08 0
167 INT278591 Localization of Eci1 1 1 0.09 0 0
168 INT274682 Localization of PTMS 3 1 0.64 0.32 0
169 INT305144 Gene_expression of NPDC1 1 1 0.25 1 0
170 INT300332 Regulation of Transcription of Atp9b 1 1 0.06 0 0
171 INT300327 Negative_regulation of Gene_expression of Myh1 3 1 0.52 0.39 0
172 INT278589 Binding of Eci1 3 1 0.04 0 0
173 INT300324 Regulation of Transcription of Myh1 5 1 0.24 0.36 0
174 INT278593 Regulation of BOP 1 1 0.16 0.08 0
175 INT300329 Regulation of Binding of Mitf 1 1 0.24 0.27 0
176 INT300330 Negative_regulation of Transcription of Myh1 3 1 0.46 0 0
177 INT300331 Positive_regulation of Transcription of Atp9b 1 1 0.11 0.09 0
178 INT300325 Positive_regulation of Transcription of Myh1 10 1 0.54 0.23 0
179 INT283374 Positive_regulation of Mstn 1 1 0.30 0.32 0
180 INT300328 Regulation of Gene_expression of Myh1 5 1 0.40 0.55 0
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