J:The Open Medicinal Chemistry Journal

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT356199 GOPC Positive_regulation of Acot7 1 1 0.04 0.33 0.4
2 INT349951 Grm7 Regulation of pcp 1 1 0.00 0.56 0.28
3 INT321917 1200011M11Rik Positive_regulation of DAO 1 1 0.01 0.9 0.27
4 INT321893 Binding of DAO and GRIN3B 1 1 0.03 0 0.19
5 INT321915 Binding of DAO and Ddo 1 1 0.07 0 0.19
6 INT321914 Negative_regulation of Binding of Ddo and GRIN3B 1 1 0.01 0 0.19
7 INT321919 Binding of DAO and Gopc 1 1 0.02 0 0.16
8 INT321918 Binding of Ddo and GRIN3B 1 1 0.01 0 0.16
9 INT321916 DAO Regulation of Dao 1 2 0.36 0.84 0.12
10 INT275771 Binding of Prep and Musd1 1 1 0.00 0 0.08

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT27096 Positive_regulation of Nfkb1 1 325 0.70 195.11 109.06
2 INT9012 Localization of Vip 1 283 0.81 31.71 106.16
3 INT403 Localization of Trh 1 241 0.81 28.55 81.45
4 INT62374 Gene_expression of NGF 2 158 0.78 77.87 76.45
5 INT1080 Negative_regulation of Ache 12 343 0.59 108.51 72.4
6 INT15913 Negative_regulation of CYP2D6 1 174 0.59 22.45 70.91
7 INT1169 Negative_regulation of Bche 3 322 0.59 149.22 61.27
8 INT69876 Negative_regulation of Nfkb1 1 147 0.58 89.81 55.5
9 INT52531 Gene_expression of Nfkb1 1 153 0.75 82.84 42.9
10 INT11439 Positive_regulation of Csf2 3 105 0.69 62.63 37.77
11 INT23330 Binding of Chrna7 1 79 0.48 10.06 35.5
12 INT692 Negative_regulation of SST 1 72 0.59 28.68 34.52
13 INT7894 Negative_regulation of Vip 1 59 0.59 11.76 27.36
14 INT2569 Gene_expression of Ache 1 120 0.78 26.29 26.89
15 INT276 Regulation of Ache 1 83 0.62 16.75 25.99
16 INT101225 Positive_regulation of Gria2 2 62 0.64 28.1 23.93
17 INT66758 Binding of Nfkb1 1 97 0.48 50.65 23.65
18 INT105021 Binding of GOPC 2 187 0.40 60.39 20.38
19 INT155683 Gene_expression of Slc1a2 1 27 0.73 9.86 15.34
20 INT7040 Binding of Vip 1 43 0.48 4.57 15.05
21 INT91913 Regulation of GRIN3B 3 16 0.61 11.48 14.44
22 INT65697 Positive_regulation of GRIN3B 1 23 0.69 12.52 13.78
23 INT174838 Localization of INCENP 1 80 0.64 19.05 12.89
24 INT48883 Negative_regulation of GRIN3B 2 19 0.54 14.53 11.5
25 INT9945 Negative_regulation of Csf2 1 35 0.51 17.85 11.22
26 INT93129 Negative_regulation of KCNH2 1 42 0.54 9.63 10.85
27 INT79556 Gene_expression of GRIN3B 2 16 0.77 7.71 10.75
28 INT1252 Binding of Ache 2 46 0.48 9.94 10.25
29 INT1218 Negative_regulation of Maob 1 24 0.59 9.76 9.39
30 INT18121 Binding of Maoa 1 20 0.48 2.4 9.3
31 INT155680 Gene_expression of Slc1a3 1 22 0.66 6.76 7.23
32 INT321907 Negative_regulation of DAO 26 1 0.51 9.08 7.07
33 INT9356 Regulation of pcp 1 22 0.58 6.26 6.69
34 INT168446 Gene_expression of Prep 2 25 0.64 15.17 5.94
35 INT84925 Transcription of NGF 2 11 0.65 4.13 3.65
36 INT79680 Binding of Grm7 5 6 0.47 2.83 3.58
37 INT61341 Positive_regulation of Prep 1 12 0.63 6.08 3.37
38 INT86602 Binding of KCNH2 3 14 0.36 4.65 2.58
39 INT141188 Gene_expression of Musd1 1 5 0.02 3.55 2.51
40 INT107448 Positive_regulation of Jak2 1 8 0.50 5.33 1.98
41 INT100940 Regulation of Negative_regulation of Nfkb1 1 5 0.35 3.59 1.91
42 INT321910 Positive_regulation of DAO 6 1 0.60 3.96 1.8
43 INT122435 Positive_regulation of Grm7 2 3 0.00 1.89 1.79
44 INT316622 Gene_expression of Dao 3 4 0.52 1.27 1.57
45 INT227424 Binding of Prep 1 6 0.35 2.61 1.39
46 INT130323 Regulation of Grm7 1 3 0.26 1.9 1.21
47 INT71541 Gene_expression of Pam 1 6 0.77 2.02 1.12
48 INT140052 Binding of Cish 1 12 0.39 1.63 1.1
49 INT201606 Negative_regulation of Glo1 1 2 0.29 1.7 1.05
50 INT321903 Gene_expression of DAO 14 14 0.67 3.19 0.79
51 INT321912 Regulation of SLC6A9 1 1 0.44 0.54 0.6
52 INT321899 Localization of DAO 3 1 0.65 0.15 0.43
53 INT94218 Positive_regulation of Regulation of Ache 1 2 0.40 0 0.38
54 INT321902 Positive_regulation of Gene_expression of DAO 6 1 0.52 2.05 0.38
55 INT321908 Binding of DAO 2 1 0.36 0.85 0.34
56 INT349950 Localization of GRM1 1 1 0.73 0.35 0.26
57 INT275767 Localization of Prep 1 1 0.15 0 0.17
58 INT321896 Binding of Ddo 1 1 0.08 0 0.16
59 INT321911 Regulation of Transcription of DAO 1 1 0.34 0 0.13
60 INT321900 Transcription of DAO 1 1 0.52 0 0.13
61 INT321904 Negative_regulation of Transcription of DAO 1 1 0.32 0 0.13
62 INT321909 Negative_regulation of Negative_regulation of DAO 1 1 0.32 0.48 0.11
63 INT321897 Regulation of Gene_expression of Dao 1 1 0.31 0.24 0.05
64 INT264054 Negative_regulation of Negative_regulation of Bche 1 6 0.41 2.49 0.04
65 INT275766 Binding of Grin3a 1 1 0.00 0.12 0.03
66 INT321906 Regulation of DAO 1 1 0.34 0.24 0.03
67 INT275765 Gene_expression of Dtnb 1 1 0.10 0 0
68 INT275776 Positive_regulation of Transcription of NGF 1 1 0.12 0.09 0
69 INT321901 Negative_regulation of Gene_expression of DAO 3 1 0.37 0 0
70 INT321905 Regulation of Negative_regulation of DAO 1 1 0.34 0.2 0
71 INT275774 Negative_regulation of Transcription of NGF 1 1 0.07 0.1 0
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