J:The Open Virology Journal

From wiki-pain
Jump to: navigation, search

This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT330379 Gene_expression of IL10 Negative_regulation of Positive_regulation of MAPK14 1 1 0.00 1.95 1.18
2 INT330377 Positive_regulation of Binding of TLR2 and TLR9 1 2 0.09 2.79 0.32
3 INT330381 Binding of TLR2 and TLR9 1 2 0.07 2.77 0.32
4 INT330389 Positive_regulation of Binding of TLR2 and TLR8 1 2 0.08 2.78 0.32
5 INT330383 Binding of TLR2 and TLR3 1 2 0.07 2.77 0.31
6 INT330378 Positive_regulation of Binding of TLR2 and TLR3 1 2 0.10 2.78 0.31
7 INT330387 Binding of TLR2 and TLR8 1 2 0.06 2.77 0.31
8 INT330382 IFNA1 Positive_regulation of Gene_expression of IL10 1 1 0.06 0.83 0.21
9 INT330371 Binding of TLR3 and Ifx 1 2 0.17 1.12 0.2
10 INT330388 Binding of PTPRC and TLR2 1 1 0.00 1.19 0.16
11 INT330370 Positive_regulation of Binding of IL10 and Il4 1 1 0.01 0.47 0.13
12 INT330369 Binding of IL10 and Il4 1 1 0.01 0.47 0.13
13 INT330380 CD40 Regulation of Gene_expression of IFNA1 1 1 0.17 0.78 0.1
14 INT330372 Ifx Positive_regulation of IFNA1 1 1 0.54 0.67 0.04
15 INT313590 Binding of C1qa and IgG 1 1 0.02 0.51 0
16 INT330384 IER3 Regulation of USH2A 1 1 0.00 0.87 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 1 3152 0.78 2515.62 929.82
2 INT68684 Gene_expression of VEGFA 2 2371 0.78 1742.52 259.2
3 INT867 Gene_expression of IFNA1 9 930 0.78 594.85 168.03
4 INT20374 Gene_expression of Il4 13 515 0.76 306.15 114.12
5 INT60526 Gene_expression of IL10 6 449 0.78 292.71 107.84
6 INT90091 Gene_expression of GOPC 2 967 0.67 366.22 103.6
7 INT65500 Gene_expression of App 3 605 0.78 429.94 98.31
8 INT11587 Gene_expression of CSF2 5 645 0.78 544.38 93.89
9 INT71789 Positive_regulation of MAPK1 1 396 0.70 234.44 89.27
10 INT96917 Positive_regulation of Mapk14 1 261 0.70 173.29 88.79
11 INT914 Positive_regulation of GH1 1 292 0.69 100.7 84.91
12 INT92434 Phosphorylation of Mapk1 1 287 0.82 91.65 83.46
13 INT75999 Gene_expression of BDNF 1 344 0.78 114.19 83.12
14 INT2289 Gene_expression of PENK 5 203 0.78 55.62 79.49
15 INT62374 Gene_expression of NGF 3 158 0.78 77.87 76.45
16 INT170332 Gene_expression of IFN1@ 1 477 0.75 275.21 69.65
17 INT4960 Positive_regulation of CSF2 1 285 0.70 256.73 65.73
18 INT5058 Positive_regulation of IFNA1 2 356 0.70 245.75 60.52
19 INT20382 Gene_expression of Hand2 1 211 0.66 142.26 51.05
20 INT531 Gene_expression of GH1 1 376 0.75 193.45 46.24
21 INT71786 Phosphorylation of MAPK1 2 256 0.82 110.09 46.17
22 INT42980 Gene_expression of GAD1 3 139 0.69 94.77 45.11
23 INT6979 Positive_regulation of CA2 1 206 0.67 50.79 44.97
24 INT18522 Positive_regulation of Gene_expression of IFNA1 1 248 0.67 160.85 44.87
25 INT1726 Positive_regulation of Kitl 1 65 0.70 38.81 44.85
26 INT80124 Negative_regulation of VEGFA 1 450 0.58 311.19 44.53
27 INT25383 Gene_expression of Csf2 1 222 0.76 152.93 43.32
28 INT133028 Gene_expression of TLR2 2 209 0.73 131.92 36.17
29 INT101992 Localization of VEGFA 1 413 0.81 258.23 36.15
30 INT49214 Gene_expression of Cd4 1 269 0.78 154.22 34.05
31 INT11325 Gene_expression of HLA-E 2 209 0.76 98.05 33.72
32 INT5489 Localization of CA2 1 172 0.80 39.46 33.56
33 INT29743 Negative_regulation of App 1 91 0.59 65.56 31.26
34 INT65960 Gene_expression of BCL2 1 352 0.78 312.03 30.73
35 INT110020 Gene_expression of Mapk14 1 142 0.77 72.33 30.08
36 INT21900 Gene_expression of Mthfd1 1 150 0.75 69.47 27.03
37 INT19856 Gene_expression of CD8A 1 240 0.75 147.86 26.39
38 INT53482 Gene_expression of ITIH4 3 75 0.77 58.87 26.05
39 INT70048 Positive_regulation of Gene_expression of IL10 1 90 0.55 71.34 25.66
40 INT89662 Positive_regulation of Gene_expression of App 1 169 0.70 133.36 25.62
41 INT172458 Regulation of Gopc 1 155 0.53 62.57 24.86
42 INT22708 Gene_expression of MUC1 1 297 0.78 232.71 24.19
43 INT17275 Gene_expression of HIVEP1 1 267 0.75 232.07 24.06
44 INT86534 Positive_regulation of MAPK14 1 81 0.62 57.81 23.62
45 INT74423 Localization of IL10 1 91 0.80 61.6 22.95
46 INT62373 Negative_regulation of NGF 1 34 0.59 25.87 22.38
47 INT171924 Gene_expression of MAPK14 1 60 0.65 54.38 21.68
48 INT116856 Gene_expression of TNFSF10 1 110 0.75 115.76 21.48
49 INT137767 Gene_expression of Eae1 1 74 0.34 89.32 20.48
50 INT14701 Negative_regulation of IFNA1 1 118 0.54 84.19 20.08
51 INT20129 Regulation of Il1 1 53 0.53 44.14 19.89
52 INT18311 Positive_regulation of CD8A 1 145 0.69 113.48 19.44
53 INT65502 Regulation of App 1 77 0.62 52.05 19.44
54 INT91462 Positive_regulation of Phosphorylation of MAPK1 1 99 0.67 40.28 18.99
55 INT192409 Positive_regulation of Gene_expression of IFN1@ 1 102 0.67 64.66 18.8
56 INT73252 Positive_regulation of Mthfd1 1 124 0.59 59.48 18.35
57 INT7056 Positive_regulation of Gene_expression of PENK 1 35 0.70 14.31 18.21
58 INT33542 Gene_expression of Il1rn 3 41 0.76 32.47 18.08
59 INT112017 Regulation of Hand2 3 77 0.36 62.23 18.04
60 INT168263 Gene_expression of IL23A 3 57 0.58 47.1 17.67
61 INT84924 Positive_regulation of Gene_expression of NGF 1 29 0.68 17.91 16.46
62 INT22900 Positive_regulation of Cd4 1 126 0.67 82.77 16.43
63 INT104045 Regulation of Hand1 1 65 0.35 51.32 16.26
64 INT97871 Gene_expression of Ntf3 3 47 0.78 25.9 15.94
65 INT9220 Gene_expression of Ighg1 1 125 0.77 85.74 15.92
66 INT170335 Gene_expression of INCENP 2 176 0.54 91.62 15.31
67 INT22301 Positive_regulation of Gene_expression of CSF2 1 66 0.63 59.49 14.24
68 INT72127 Protein_catabolism of MMRN1 4 68 0.52 56 14.13
69 INT18012 Gene_expression of EPO 1 169 0.78 108.36 13.75
70 INT5207 Negative_regulation of Alms1 1 70 0.41 41.56 13.68
71 INT2385 Gene_expression of MIF 1 57 0.68 40.74 12.78
72 INT69029 Gene_expression of PTPRC 1 127 0.75 74.26 11.57
73 INT85048 Regulation of NGF 1 19 0.62 11.61 10.5
74 INT150540 Binding of TLR2 2 50 0.45 35.86 10.43
75 INT21952 Gene_expression of GDNF 2 42 0.78 20.32 9.62
76 INT21214 Negative_regulation of Gene_expression of PENK 1 21 0.58 9.14 9.53
77 INT182137 Gene_expression of TLR9 1 137 0.78 48.48 9.05
78 INT173587 Protein_catabolism of COL5A2 1 59 0.32 32.73 8.96
79 INT61264 Regulation of Jun 1 36 0.61 18.42 8.71
80 INT25392 Positive_regulation of Gene_expression of Csf2 1 41 0.49 34.28 8.36
81 INT92680 Gene_expression of Fgf2 1 59 0.77 28.11 8.12
82 INT175526 Phosphorylation of Gopc 2 73 0.53 21.08 7.86
83 INT97870 Positive_regulation of Gene_expression of Ntf3 1 19 0.70 9.56 7.8
84 INT1664 Gene_expression of Kitl 1 30 0.65 13.63 7.47
85 INT51741 Regulation of Gene_expression of Il4 1 23 0.36 12.7 7.39
86 INT50212 Gene_expression of Ifx 10 33 0.75 32.17 7.26
87 INT63373 Negative_regulation of Gene_expression of NGF 1 14 0.57 8.9 7.1
88 INT137206 Positive_regulation of TLR2 2 47 0.65 33.36 6.4
89 INT56160 Binding of Ifx 1 14 0.36 11.39 5.74
90 INT187133 Protein_catabolism of TIMP1 1 19 0.73 11.3 5.51
91 INT126751 Regulation of Gene_expression of IL10 1 16 0.44 10.84 5.22
92 INT83442 Negative_regulation of MIF 1 18 0.57 9.51 5.12
93 INT175312 Positive_regulation of Gene_expression of IL23A 1 17 0.45 14.8 5.05
94 INT84057 Positive_regulation of Gene_expression of ITIH4 1 12 0.50 10.5 4.92
95 INT105393 Positive_regulation of Localization of VEGFA 1 66 0.70 45.45 4.9
96 INT130290 Positive_regulation of Localization of IL10 1 16 0.47 9.38 4.75
97 INT188588 Localization of Mthfd1 1 20 0.49 9.19 4.37
98 INT137178 Gene_expression of TLR3 3 46 0.72 24.97 4.33
99 INT1209 Binding of Kitl 2 14 0.37 6.72 4.3
100 INT204529 Positive_regulation of TLR9 1 18 0.62 15.62 3.99
101 INT68269 Gene_expression of CD99 1 49 0.77 47.38 3.86
102 INT144231 Gene_expression of Il12b 5 18 0.75 12.93 3.65
103 INT65072 Gene_expression of TKT 6 16 0.65 17.58 3.55
104 INT175531 Positive_regulation of Phosphorylation of Gopc 1 11 0.33 2.53 3.54
105 INT5609 Regulation of Ifx 1 6 0.60 5.73 3.5
106 INT66585 Gene_expression of IER3 2 13 0.63 7.39 3.48
107 INT5286 Gene_expression of ANTXR2 1 46 0.75 21.06 3.41
108 INT178631 Phosphorylation of ESR1 2 21 0.75 9.16 3.36
109 INT130441 Phosphorylation of MARCKS 1 8 0.37 3.24 3.09
110 INT116228 Binding of C1qa 1 26 0.47 15.72 3
111 INT47011 Positive_regulation of Gusb 1 14 0.44 8.93 2.87
112 INT188590 Positive_regulation of Gene_expression of Mthfd1 1 23 0.49 16.56 2.84
113 INT204524 Binding of TLR9 1 17 0.43 11.69 2.76
114 INT62487 Localization of HIVEP1 1 35 0.73 36.24 2.72
115 INT90875 Negative_regulation of CCND1 1 31 0.42 26.22 2.66
116 INT75685 Regulation of CD86 1 12 0.58 3.55 2.66
117 INT133029 Regulation of TLR2 1 18 0.56 11.31 2.62
118 INT120483 Localization of ITIH4 2 11 0.69 12.05 2.51
119 INT36338 Gene_expression of NRP2 1 29 0.67 6.47 2.4
120 INT181015 Gene_expression of C3ar1 1 12 0.58 8.9 2.18
121 INT89253 Regulation of Mthfd1 1 14 0.23 8.1 1.94
122 INT184006 Gene_expression of Ighg2b 1 21 0.71 7.97 1.86
123 INT96797 Negative_regulation of ITIH4 1 5 0.42 3.21 1.8
124 INT23148 Gene_expression of RUNX1 1 10 0.10 6.58 1.71
125 INT165213 Regulation of Gene_expression of Cd4 1 12 0.40 9.14 1.57
126 INT60162 Gene_expression of Ie 3 41 0.58 23.77 1.52
127 INT3164 Positive_regulation of GUSB 1 4 0.49 2.67 1.47
128 INT27762 Positive_regulation of Gene_expression of EPO 1 18 0.70 17.67 1.45
129 INT175636 Positive_regulation of Protein_catabolism of MMRN1 1 8 0.30 11.38 1.39
130 INT67133 Gene_expression of Gusb 3 14 0.75 18.57 1.37
131 INT186810 Positive_regulation of TLR3 1 13 0.65 6.37 1.37
132 INT53198 Positive_regulation of Positive_regulation of Cd4 1 6 0.49 3.75 1.36
133 INT92383 Gene_expression of KRAS 1 38 0.65 32.94 1.32
134 INT79358 Gene_expression of ERVW-1 2 65 0.75 29.9 1.31
135 INT74254 Binding of PTPRC 1 16 0.36 8.37 1.27
136 INT119827 Gene_expression of PTPN11 1 31 0.75 24.21 1.22
137 INT127900 Phosphorylation of EIF2AK3 1 14 0.80 7.99 1.22
138 INT88568 Positive_regulation of RRM1 1 4 0.41 1.81 1.14
139 INT60286 Gene_expression of PKLR 2 5 0.65 2.14 1.04
140 INT178483 Gene_expression of Col18a1 1 12 0.75 11.87 1.03
141 INT130444 Positive_regulation of MARCKS 1 2 0.12 0.61 1.02
142 INT58692 Regulation of Gene_expression of CD8A 1 11 0.42 10.16 1
143 INT147088 Gene_expression of HHEX 1 5 0.65 4.86 0.99
144 INT231560 Negative_regulation of Gene_expression of IL23A 1 3 0.11 2.41 0.99
145 INT56151 Positive_regulation of Positive_regulation of CD8A 1 11 0.34 9.74 0.94
146 INT60728 Gene_expression of Serpinb1-ps1 1 10 0.59 6.92 0.93
147 INT51262 Positive_regulation of TKT 1 7 0.69 4.31 0.82
148 INT186804 Binding of TLR3 1 14 0.45 8.41 0.79
149 INT114625 Gene_expression of KPNB1 1 5 0.42 0.87 0.72
150 INT183399 Gene_expression of Cyp2b10 1 17 0.39 18.39 0.71
151 INT236320 Regulation of HLA-DRB1 1 10 0.45 6 0.69
152 INT157073 Positive_regulation of PKLR 1 6 0.36 5.48 0.69
153 INT322032 Binding of TLR8 1 3 0.32 2.57 0.69
154 INT330333 Gene_expression of Lap2 1 1 0.17 1.57 0.69
155 INT186801 Positive_regulation of Binding of TLR2 1 3 0.42 2.05 0.67
156 INT139078 Gene_expression of Tnip1 2 2 0.51 1.93 0.64
157 INT330363 Positive_regulation of Gene_expression of HHEX 1 1 0.11 1.71 0.62
158 INT213410 Localization of TKT 2 3 0.71 1.89 0.61
159 INT185240 Binding of Fgf2 1 14 0.37 7.39 0.59
160 INT60289 Negative_regulation of PKLR 1 5 0.21 1.75 0.53
161 INT330393 Positive_regulation of Gene_expression of Il12b 1 2 0.49 1.24 0.48
162 INT173968 Regulation of Gene_expression of Ifx 1 2 0.60 1.77 0.48
163 INT238502 Regulation of CD40 1 6 0.28 3.7 0.44
164 INT98072 Gene_expression of LAT 2 5 0.68 5.37 0.44
165 INT252737 Gene_expression of RAF1 1 12 0.58 10.97 0.42
166 INT192806 Binding of SSRP1 1 11 0.27 9.12 0.37
167 INT179532 Protein_catabolism of C3 1 5 0.26 1.61 0.34
168 INT207897 Positive_regulation of TLR8 1 3 0.17 2.52 0.33
169 INT23411 Negative_regulation of Tnip1 1 5 0.38 1.15 0.32
170 INT298355 Regulation of CD83 1 5 0.24 2.98 0.32
171 INT228433 Negative_regulation of Gene_expression of TKT 1 2 0.35 1.13 0.32
172 INT192226 Gene_expression of BAI1 1 4 0.26 2.99 0.3
173 INT330334 Localization of Ifx 2 1 0.73 1.36 0.29
174 INT330361 Regulation of Gene_expression of KPNB1 1 1 0.01 0.61 0.28
175 INT330335 Negative_regulation of Gene_expression of Ifx 1 1 0.41 1.07 0.28
176 INT330332 Positive_regulation of Regulation of Ifx 1 1 0.49 1.49 0.25
177 INT308129 Positive_regulation of Positive_regulation of RRM1 1 2 0.04 0.82 0.24
178 INT263492 Positive_regulation of Regulation of Hand2 1 3 0.19 4.76 0.21
179 INT294675 Localization of Il12b 1 2 0.78 1.15 0.19
180 INT269109 Negative_regulation of Cyp2b10 1 2 0.08 2.9 0.17
181 INT174246 Localization of Cyp2b1 1 2 0.68 1.58 0.17
182 INT121338 Binding of MTUS1 1 5 0.07 3.41 0.16
183 INT230419 Gene_expression of NUDCD1 1 2 0.06 1.16 0.16
184 INT184651 Gene_expression of RRM1 1 6 0.48 3.46 0.15
185 INT208039 Gene_expression of UTS2R 1 14 0.43 4.95 0.13
186 INT184649 Localization of RRM1 1 3 0.07 1.08 0.13
187 INT183206 Regulation of UTS2R 2 5 0.13 3.17 0.12
188 INT330336 Regulation of Positive_regulation of Gusb 1 1 0.16 1.05 0.12
189 INT184511 Positive_regulation of Negative_regulation of VEGFA 1 5 0.46 2.86 0.09
190 INT185394 Binding of PVRL1 1 5 0.14 2.94 0.09
191 INT330353 Positive_regulation of Gene_expression of RRM1 1 1 0.04 1.01 0.06
192 INT330365 Positive_regulation of Localization of RRM1 1 1 0.04 1.01 0.06
193 INT330331 Gene_expression of Aprt 1 1 0.01 1.09 0.04
194 INT174190 Regulation of Gene_expression of TKT 1 4 0.43 2.99 0.03
195 INT219849 Regulation of Oas1b 1 2 0.25 2 0.03
196 INT244552 Positive_regulation of PPP1R15A 1 4 0.22 2.45 0
197 INT244554 Gene_expression of PPP1R15A 1 2 0.24 1.17 0
198 INT173088 Localization of BAI1 1 2 0.29 2.71 0
199 INT244570 Transcription of PPP1R15A 1 2 0.21 1.1 0
200 INT244501 Positive_regulation of Gene_expression of PPP1R15A 1 2 0.19 1.18 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox