J:Thromb. Haemost.

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT103031 Calca Positive_regulation of Ptgs1 2 1 0.46 0.98 1.22
2 INT111924 Cpb2 Negative_regulation of Positive_regulation of Plg 1 2 0.02 1.29 0.9
3 INT167907 Binding of F2r and ITS 1 1 0.01 0.7 0.55
4 INT123663 F2R Positive_regulation of MAPK14 1 1 0.12 0.42 0.26
5 INT135965 Calca Negative_regulation of Gene_expression of Tnf 1 1 0.33 0.72 0.26
6 INT123662 Negative_regulation of F2R Positive_regulation of MAPK14 1 1 0.08 0.42 0.26
7 INT123661 COL7A1 Positive_regulation of MAPK14 1 1 0.08 0.42 0.26
8 INT123660 F2R Positive_regulation of PAR1 2 1 0.10 1.96 0.22
9 INT115006 Binding of Serpine1 and Cpb2 1 2 0.09 1.53 0.2
10 INT123664 F2R Positive_regulation of PAR4 1 1 0.03 0.51 0.19
11 INT97820 Serpine1 Negative_regulation of TIMP1 1 1 0.00 0.29 0.17

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT2542 Localization of Calca 7 2008 0.81 518.3 1408.65
2 INT1912 Gene_expression of Calca 1 1152 0.78 453.25 739.84
3 INT2543 Positive_regulation of Calca 3 787 0.70 331.13 592.08
4 INT50058 Negative_regulation of Cpox 4 907 0.58 426.28 428.29
5 INT4758 Positive_regulation of Localization of Calca 5 557 0.70 138.55 411.04
6 INT2540 Negative_regulation of Calca 2 538 0.59 172.11 384.38
7 INT6580 Negative_regulation of Ptgs1 1 929 0.59 381.53 376.26
8 INT5235 Negative_regulation of TNF 1 924 0.59 772.91 331.98
9 INT9158 Gene_expression of Tnf 2 722 0.78 522.01 277.68
10 INT15516 Gene_expression of Crp 2 711 0.77 615.33 173.09
11 INT51921 Gene_expression of Cpox 1 501 0.73 229.81 157.81
12 INT11587 Gene_expression of CSF2 1 645 0.78 544.38 93.89
13 INT52800 Negative_regulation of Gene_expression of Tnf 2 142 0.59 92.27 55.47
14 INT78899 Gene_expression of CCL5 2 155 0.77 84.02 55.09
15 INT52264 Gene_expression of IK 1 180 0.77 90.87 51.87
16 INT1232 Positive_regulation of Pdpk1 1 78 0.42 24.33 50.17
17 INT22454 Regulation of Crp 5 213 0.62 160.67 49.24
18 INT5033 Negative_regulation of tf 2 39 0.54 13.37 48.62
19 INT2774 Binding of Crp 1 241 0.48 195.89 44.39
20 INT4216 Gene_expression of CD40LG 1 328 0.78 256.02 44.23
21 INT18992 Negative_regulation of Pdpk1 1 53 0.42 19.02 40.95
22 INT4862 Localization of PENK 1 62 0.81 11.57 40.28
23 INT11560 Positive_regulation of CASP3 1 236 0.70 184.33 39.38
24 INT47939 Gene_expression of Selp 2 171 0.76 87.54 39.03
25 INT51017 Positive_regulation of Icam1 1 113 0.70 81.16 35.55
26 INT16960 Gene_expression of Crp 1 166 0.76 116.21 34.07
27 INT11361 Gene_expression of SERPINE1 2 183 0.78 136.45 27.97
28 INT5653 Positive_regulation of ELANE 1 136 0.70 72.78 27.94
29 INT53949 Positive_regulation of Gene_expression of Cpox 1 82 0.65 38.12 25.93
30 INT49141 Gene_expression of Selp 3 157 0.78 85.22 24.78
31 INT86534 Positive_regulation of MAPK14 1 81 0.62 57.81 23.62
32 INT69322 Negative_regulation of MAPK14 2 70 0.54 42.92 22.71
33 INT14731 Positive_regulation of TGFB1 1 78 0.67 52.57 22.23
34 INT23224 Gene_expression of tf 3 99 0.56 60.22 22.03
35 INT9079 Gene_expression of PPBP 7 52 0.75 31.2 21.52
36 INT2978 Gene_expression of Tbxa2r 1 76 0.77 28.4 21.27
37 INT78901 Localization of CCL5 1 67 0.78 40.79 20.59
38 INT49103 Positive_regulation of Vcam1 8 71 0.69 59.52 19.85
39 INT49487 Gene_expression of Sele 1 65 0.76 68.11 19.41
40 INT18010 Positive_regulation of CD40LG 3 122 0.70 100.8 18.46
41 INT9900 Positive_regulation of Vwf 5 80 0.69 51.85 18.13
42 INT117500 Gene_expression of Adipoq 2 90 0.74 67.79 16.58
43 INT109929 Phosphorylation of MAPK8 1 102 0.81 39.98 16.54
44 INT899 Gene_expression of F13A1 3 122 0.70 78.02 16.26
45 INT1888 Protein_catabolism of F13A1 3 97 0.99 63.48 14.82
46 INT11636 Positive_regulation of SERPINE1 1 85 0.69 68.73 14.8
47 INT25493 Gene_expression of TFPI 2 74 0.76 39.44 14.78
48 INT59870 Gene_expression of F3 1 51 0.65 51.83 14.01
49 INT11069 Positive_regulation of Pf4 1 35 0.68 27.7 13.96
50 INT15684 Positive_regulation of Serpine1 5 65 0.70 43.51 13.67
51 INT11071 Positive_regulation of PPBP 1 43 0.68 26.85 13.43
52 INT15921 Positive_regulation of Serpine1 16 85 0.68 81.24 13.4
53 INT71510 Positive_regulation of Selp 2 47 0.68 30.43 12.8
54 INT2129 Positive_regulation of F2 1 83 0.70 58.95 12.63
55 INT20102 Gene_expression of Serpine1 2 102 0.78 65.99 12.61
56 INT8629 Positive_regulation of COL7A1 2 72 0.69 40.66 12.09
57 INT117502 Positive_regulation of Adipoq 1 70 0.63 40.43 12.03
58 INT49142 Gene_expression of SELP 3 94 0.75 54.61 11.64
59 INT1190 Positive_regulation of F2 3 53 0.70 46.41 11.64
60 INT13240 Gene_expression of TF 3 94 0.76 57.81 10.99
61 INT14962 Gene_expression of Pf4 5 27 0.76 22.48 10.88
62 INT4240 Positive_regulation of CCL5 1 32 0.58 20.55 10.65
63 INT110178 Phosphorylation of MAPK14 1 40 0.68 19.38 10.37
64 INT78895 Regulation of CCL5 1 30 0.46 20.45 10.18
65 INT2378 Negative_regulation of SERPINE1 1 47 0.59 34.55 9.9
66 INT10139 Positive_regulation of F13A1 1 64 0.56 44.75 9.69
67 INT68373 Negative_regulation of FLNA 1 59 0.57 60.46 9.55
68 INT3366 Localization of PLEK 2 44 0.78 15.83 9.55
69 INT68372 Regulation of CYP2C9 2 28 0.62 5.64 9.53
70 INT9899 Gene_expression of Vwf 4 91 0.74 45.06 9.13
71 INT66819 Binding of CYP2C9 1 41 0.48 8.23 8.76
72 INT4159 Gene_expression of Hp 1 33 0.72 12.49 8.39
73 INT30526 Negative_regulation of PTAFR 1 15 0.58 8.15 8.19
74 INT60034 Positive_regulation of VWF 1 40 0.68 30.42 8.15
75 INT51458 Negative_regulation of Gene_expression of Selp 1 29 0.57 12.64 8.1
76 INT81777 Negative_regulation of Gene_expression of IK 1 22 0.08 11.55 8.09
77 INT2271 Gene_expression of F2 3 51 0.76 30.21 7.97
78 INT67424 Positive_regulation of Gene_expression of Selp 1 36 0.68 17.08 7.95
79 INT62944 Regulation of Icam1 1 33 0.47 23.52 7.94
80 INT1925 Gene_expression of PLAT 2 47 0.75 34.76 7.88
81 INT15918 Gene_expression of Serpine1 7 60 0.62 41.73 7.72
82 INT81399 Regulation of Vcam1 2 24 0.46 23.53 7.68
83 INT1963 Positive_regulation of Adp 1 12 0.11 3.73 7.6
84 INT65489 Regulation of Gene_expression of Crp 1 28 0.59 29.17 7.56
85 INT123459 Gene_expression of Tnfrsf11b 1 35 0.58 24.16 7.26
86 INT11042 Localization of Tbxa2r 1 26 0.76 10.15 7.24
87 INT10863 Positive_regulation of Ldlr 1 45 0.68 31.06 7.05
88 INT1038 Negative_regulation of F2 1 26 0.58 15.12 6.75
89 INT16389 Gene_expression of Plg 1 80 0.67 36.88 6.74
90 INT1926 Positive_regulation of PLAT 5 54 0.66 31.42 6.49
91 INT5146 Localization of PPBP 1 32 0.81 12.5 6.08
92 INT18677 Gene_expression of F3 1 50 0.65 30.86 5.86
93 INT81049 Positive_regulation of CASP1 2 44 0.67 19.97 5.69
94 INT8866 Positive_regulation of TAT 1 30 0.67 18.06 5.57
95 INT22597 Positive_regulation of TF 1 43 0.68 27.27 5.17
96 INT2919 Negative_regulation of F8 2 47 0.59 23.48 5.1
97 INT139803 Gene_expression of PTX3 1 22 0.75 26.21 5.07
98 INT10889 Gene_expression of F8 1 60 0.78 41.36 5.06
99 INT15941 Negative_regulation of Serpine1 1 42 0.58 21.07 4.95
100 INT28703 Negative_regulation of TFPI 1 29 0.38 19.81 4.93
101 INT15920 Regulation of Serpine1 3 34 0.42 17.36 4.89
102 INT23225 Negative_regulation of Gene_expression of tf 1 7 0.34 3.66 4.87
103 INT28269 Negative_regulation of Adp 1 18 0.36 5.98 4.74
104 INT35609 Negative_regulation of F10 1 37 0.57 17.15 4.41
105 INT130083 Positive_regulation of Positive_regulation of Vcam1 3 8 0.36 5.81 4.31
106 INT9080 Regulation of PPBP 1 17 0.44 5.75 4.3
107 INT11635 Positive_regulation of Gene_expression of SERPINE1 1 35 0.68 24.57 4.26
108 INT4239 Negative_regulation of CCL5 1 15 0.40 10.92 4.26
109 INT110181 Negative_regulation of Phosphorylation of MAPK8 1 20 0.57 9.43 4.06
110 INT63880 Positive_regulation of FLNA 1 29 0.59 13.88 3.97
111 INT51831 Negative_regulation of ITGA2B 6 20 0.57 10.59 3.91
112 INT44323 Positive_regulation of F8 3 32 0.60 24.88 3.89
113 INT110180 Phosphorylation of JUN 1 23 0.80 11.21 3.83
114 INT9077 Regulation of Tbxa2r 1 13 0.45 5.49 3.75
115 INT63979 Regulation of Sele 1 13 0.54 10.64 3.7
116 INT14717 Gene_expression of TAT 1 20 0.75 10.67 3.66
117 INT16644 Positive_regulation of Plg 2 16 0.60 6.38 3.62
118 INT16263 Regulation of Serpine1 1 13 0.45 5.24 3.6
119 INT54102 Positive_regulation of Gene_expression of TFPI 1 14 0.49 6.67 3.54
120 INT28802 Binding of F2 2 15 0.47 8.8 3.47
121 INT22823 Positive_regulation of Positive_regulation of ELANE 1 12 0.45 6.89 3.35
122 INT14397 Gene_expression of Serpinc1 1 27 0.46 14.54 3.32
123 INT93343 Gene_expression of Cpb2 5 10 0.58 4.63 3.24
124 INT27740 Positive_regulation of COX8A 2 16 0.67 9.66 3.23
125 INT78898 Regulation of Gene_expression of CCL5 1 9 0.42 5.7 3.11
126 INT22429 Positive_regulation of PDAP1 1 34 0.61 22.58 2.91
127 INT41358 Localization of Pf4 1 11 0.79 6.06 2.89
128 INT110039 Positive_regulation of Nppb 1 38 0.53 34.54 2.88
129 INT32394 Regulation of Pf4 2 12 0.23 6.07 2.85
130 INT28891 Localization of Selp 1 13 0.60 8.23 2.83
131 INT83642 Gene_expression of CD63 1 22 0.77 10.06 2.63
132 INT9374 Regulation of Plat 1 19 0.61 6.04 2.55
133 INT56918 Negative_regulation of TAT 1 11 0.57 5.92 2.44
134 INT48635 Negative_regulation of Pts 1 15 0.49 15.38 2.43
135 INT102659 Gene_expression of CSF3 1 32 0.77 21.93 2.39
136 INT104041 Positive_regulation of Cpb2 2 7 0.59 2.88 2.39
137 INT110179 Negative_regulation of Phosphorylation of MAPK14 1 11 0.36 5.25 2.38
138 INT25121 Negative_regulation of Positive_regulation of COL7A1 1 5 0.24 1.32 2.37
139 INT38871 Binding of TFPI 1 12 0.32 5.9 2.36
140 INT111922 Binding of Cpb2 4 3 0.41 3.12 2.3
141 INT19669 Positive_regulation of SPANXA1 1 4 0.22 1.93 2.29
142 INT19668 Regulation of SPANXA1 1 4 0.16 1.21 2.26
143 INT57360 Gene_expression of STAR 2 31 0.66 12.72 2.24
144 INT23352 Negative_regulation of A2M 1 10 0.33 8.35 2.16
145 INT15922 Positive_regulation of Positive_regulation of Serpine1 2 6 0.31 8.34 2.16
146 INT66261 Negative_regulation of Ccl21a 1 5 0.42 1.04 2.1
147 INT123458 Positive_regulation of Tnfrsf11b 2 9 0.43 14.3 2.01
148 INT123671 Positive_regulation of PAR1 1 7 0.39 5.1 1.95
149 INT32190 Binding of Adp 1 9 0.12 2.42 1.91
150 INT142477 Gene_expression of GP6 7 12 0.76 12.53 1.79
151 INT162636 Localization of PTX3 1 8 0.78 9.73 1.77
152 INT39513 Positive_regulation of TRAP 1 14 0.48 5.11 1.67
153 INT122058 Negative_regulation of VKORC1 2 1 0.39 0.18 1.63
154 INT3249 Regulation of A2M 2 7 0.39 3.29 1.61
155 INT33133 Positive_regulation of ITGA2B 1 13 0.67 4.09 1.44
156 INT54593 Positive_regulation of Gene_expression of TF 1 16 0.68 9.05 1.43
157 INT28892 Positive_regulation of Localization of Selp 1 3 0.35 1.04 1.4
158 INT88550 Positive_regulation of PAR4 1 6 0.68 6.61 1.25
159 INT81776 Positive_regulation of F3 1 8 0.07 3.77 1.21
160 INT20100 Binding of Serpine1 2 16 0.29 6.78 1.18
161 INT15919 Positive_regulation of Gene_expression of Serpine1 1 6 0.41 4.5 1.15
162 INT35148 Regulation of ANGPTL5 1 12 0.28 6.92 1.14
163 INT111923 Regulation of Cpb2 2 1 0.33 1.3 1.08
164 INT48944 Binding of Pts 1 8 0.41 3.23 1.03
165 INT27587 Positive_regulation of STAR 2 7 0.46 6.37 0.99
166 INT115471 Binding of Sele 2 5 0.36 4.06 0.94
167 INT80385 Binding of GP9 1 4 0.35 0.26 0.89
168 INT142423 Negative_regulation of Positive_regulation of FLNA 1 2 0.05 0.99 0.89
169 INT96678 Binding of TAT 1 3 0.47 6.75 0.85
170 INT122056 Regulation of Ggcx 1 1 0.06 0 0.83
171 INT122057 Regulation of VKORC1 1 1 0.18 0.05 0.83
172 INT79181 Negative_regulation of GP1BA 1 2 0.06 2.23 0.8
173 INT76751 Negative_regulation of Protein_catabolism of F13A1 1 7 0.13 5.16 0.79
174 INT81774 Negative_regulation of F3 1 5 0.09 3.71 0.79
175 INT162635 Positive_regulation of Localization of PTX3 1 2 0.49 4.86 0.78
176 INT142421 Regulation of Positive_regulation of Vcam1 1 2 0.19 1.53 0.78
177 INT142422 Regulation of Positive_regulation of ELANE 1 1 0.02 0.65 0.78
178 INT81775 Localization of F3 1 10 0.61 9.12 0.73
179 INT142478 Positive_regulation of Gene_expression of GP6 2 6 0.68 4.5 0.73
180 INT33733 Binding of ITGA2B 1 12 0.36 3.86 0.71
181 INT64518 Positive_regulation of ITS 1 2 0.49 1.19 0.7
182 INT118310 Negative_regulation of Positive_regulation of Adipoq 1 2 0.34 2.47 0.61
183 INT123672 Positive_regulation of F2R 1 9 0.47 0.77 0.58
184 INT135419 Binding of Tnfrsf11b 1 5 0.34 4.15 0.53
185 INT20099 Regulation of Positive_regulation of Serpine1 1 2 0.40 1.75 0.52
186 INT84180 Binding of F5 1 22 0.48 18.6 0.49
187 INT58015 Regulation of Gene_expression of Serpine1 1 3 0.41 2.61 0.47
188 INT160663 Positive_regulation of Dazap2 1 3 0.27 1.92 0.47
189 INT35435 Negative_regulation of Positive_regulation of Serpine1 3 5 0.42 2.26 0.46
190 INT33737 Negative_regulation of Binding of ITGA2B 1 3 0.41 0.29 0.44
191 INT20101 Regulation of Positive_regulation of Serpine1 1 1 0.10 0.94 0.44
192 INT2527 Positive_regulation of Pf4 1 2 0.22 0.77 0.42
193 INT2528 Negative_regulation of Pf4 1 2 0.19 0.16 0.41
194 INT92248 Negative_regulation of F5 1 7 0.43 3.28 0.4
195 INT73667 Positive_regulation of F5 1 6 0.60 3.38 0.39
196 INT47625 Negative_regulation of IFIH1 1 4 0.51 1.68 0.39
197 INT87310 Gene_expression of fm 2 1 0.04 0.34 0.39
198 INT87309 Gene_expression of Serpinf2 1 1 0.00 0.34 0.39
199 INT66142 Positive_regulation of F11 3 1 0.22 0.84 0.37
200 INT41739 Gene_expression of CD109 1 1 0.14 0.97 0.33
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