J:Tob Induc Dis

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT205152 Binding of CD44 and MMP9 23 2 0.35 17.13 1.85
2 INT267133 Binding of ICAM1 and VCAM1 25 24 0.32 25.43 1.83
3 INT71176 Binding of ICAM1 and ITGB2 4 2 0.21 4.93 1.07
4 INT220148 Binding of IGF1 and IGFBP3 12 2 0.36 5.56 0.66
5 INT267138 Binding of CDH5 and PECAM1 2 2 0.16 2.69 0.16
6 INT267124 IGF1 Negative_regulation of Gene_expression of INS 2 2 0.14 0.18 0.1
7 INT267137 ICAM1 Regulation of ITGAL 2 2 0.12 0.57 0.07
8 INT267136 Binding of CD44 and FN1 2 2 0.04 0.56 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT287 Localization of Cck 1 518 0.81 86.84 364.04
2 INT63932 Positive_regulation of Ephb1 3 537 0.70 259.67 296.14
3 INT2365 Positive_regulation of Cck 5 354 0.70 87.8 277.41
4 INT5972 Gene_expression of IL1B 2 948 0.78 510.91 263.97
5 INT1902 Gene_expression of Cck 3 348 0.78 70.33 241.92
6 INT943 Negative_regulation of Cck 1 205 0.59 38.42 174.78
7 INT2366 Binding of Cck 2 192 0.48 30.64 163.46
8 INT3038 Gene_expression of INS 2 1583 0.78 1174.16 107.01
9 INT69440 Gene_expression of ROS1 3 752 0.78 477.64 103.83
10 INT48408 Gene_expression of ICAM1 54 494 0.78 340.08 88.6
11 INT17401 Gene_expression of IGF1 10 475 0.78 232.18 62.07
12 INT1200 Negative_regulation of Ins1 4 274 0.58 155.17 56.14
13 INT5025 Positive_regulation of Gene_expression of Cck 3 63 0.70 10.96 47.11
14 INT89 Positive_regulation of Gast 4 187 0.70 80.49 42.07
15 INT30 Gene_expression of Gast 2 158 0.78 99 41.45
16 INT69437 Positive_regulation of ROS1 1 328 0.58 222.83 40.56
17 INT63349 Gene_expression of PECAM1 22 199 0.75 166.03 36.76
18 INT2416 Negative_regulation of MAOA 4 92 0.59 42.24 36.5
19 INT62827 Positive_regulation of ICAM1 56 184 0.70 180.95 36.28
20 INT74563 Positive_regulation of Gene_expression of ROS1 2 258 0.61 168.18 34.08
21 INT48924 Positive_regulation of Mapk3 2 107 0.67 50.53 34.05
22 INT62830 Gene_expression of VCAM1 8 149 0.78 125.23 32.4
23 INT10915 Gene_expression of ITGAM 12 164 0.78 92.42 29.78
24 INT9682 Positive_regulation of IGF1 6 238 0.70 120.03 26.36
25 INT15089 Regulation of SLC6A4 2 48 0.62 17.87 25.6
26 INT147792 Gene_expression of COPD 2 230 0.70 287.13 24.1
27 INT49196 Gene_expression of SELE 10 105 0.78 107.29 22.92
28 INT23257 Regulation of CRP 2 127 0.62 100.05 21.87
29 INT28216 Gene_expression of HRAS 2 173 0.75 93.97 20.78
30 INT49774 Binding of DRD2 4 48 0.48 17.42 20.73
31 INT63340 Positive_regulation of Gene_expression of ICAM1 15 109 0.70 90.82 20.61
32 INT7581 Binding of ADHD1 2 132 0.46 135.1 19.73
33 INT135629 Binding of COMT 2 33 0.48 16.68 19.37
34 INT28951 Negative_regulation of IGF1 4 133 0.59 75.77 18.9
35 INT62826 Negative_regulation of Gene_expression of ICAM1 6 75 0.58 46.39 17.72
36 INT2216 Gene_expression of SELL 4 92 0.77 59.29 17.71
37 INT10918 Gene_expression of ITGB2 18 93 0.76 71.8 16.34
38 INT69435 Negative_regulation of ROS1 1 74 0.51 50.38 13.71
39 INT63361 Gene_expression of CD44 22 126 0.77 71.58 12.96
40 INT49975 Binding of SLC6A3 4 34 0.47 9.86 12.41
41 INT69436 Negative_regulation of Gene_expression of ROS1 1 81 0.38 46.58 12.22
42 INT73829 Positive_regulation of Gene_expression of VCAM1 3 41 0.61 35.96 11.92
43 INT21467 Negative_regulation of Binding of Cck 2 18 0.57 2.84 11.91
44 INT2415 Binding of MAOA 4 26 0.47 13.26 11.86
45 INT49142 Gene_expression of SELP 6 94 0.75 54.61 11.64
46 INT65713 Localization of ICAM1 8 42 0.81 39.55 11.49
47 INT56448 Regulation of ICAM1 16 52 0.60 55.1 10.96
48 INT14780 Regulation of Binding of Cck 2 9 0.49 4.33 10.83
49 INT94784 Binding of ROS1 1 113 0.40 71.57 10.26
50 INT10041 Protein_catabolism of Cck 2 18 0.96 2.71 9.81
51 INT80549 Binding of ICAM1 10 53 0.47 42.76 9.72
52 INT11729 Regulation of IGF1 4 71 0.61 44.58 9.71
53 INT63341 Negative_regulation of ICAM1 12 42 0.59 30.45 9.5
54 INT62829 Positive_regulation of VCAM1 6 39 0.70 38.42 9.15
55 INT1118 Gene_expression of C6orf25 4 73 0.77 47.24 9.1
56 INT63338 Regulation of Gene_expression of ICAM1 8 42 0.62 28.26 9.06
57 INT173587 Protein_catabolism of COL5A2 2 59 0.32 32.73 8.96
58 INT48725 Gene_expression of IGFBP3 14 128 0.78 78.83 8.19
59 INT82762 Positive_regulation of Positive_regulation of Mapk3 1 23 0.67 7.72 7.91
60 INT30777 Negative_regulation of SELL 2 20 0.56 18.05 7.32
61 INT64792 Positive_regulation of Gene_expression of ITGAM 4 39 0.69 23.21 6.71
62 INT10917 Positive_regulation of ITGAM 2 31 0.67 16.39 6.69
63 INT90461 Negative_regulation of DRD2 2 21 0.53 8.35 6.55
64 INT61417 Gene_expression of ITGAL 2 36 0.75 29.62 6.15
65 INT63351 Negative_regulation of Gene_expression of PECAM1 2 19 0.52 16.06 5.73
66 INT53684 Negative_regulation of Gene_expression of ITGAM 2 23 0.59 14.36 5.66
67 INT65712 Positive_regulation of Localization of ICAM1 4 14 0.70 16.72 5.5
68 INT62525 Positive_regulation of SELE 4 38 0.70 46 5.25
69 INT49801 Positive_regulation of SELP 6 21 0.48 21.34 5.25
70 INT56364 Regulation of Gene_expression of ITGAM 1 19 0.61 9.82 5.09
71 INT62822 Positive_regulation of Gene_expression of SELE 2 22 0.66 28.04 4.97
72 INT49130 Positive_regulation of IGFBP3 2 49 0.63 27.55 4.78
73 INT87632 Positive_regulation of Gene_expression of PECAM1 4 32 0.45 29.47 4.66
74 INT51898 Binding of PECAM1 6 26 0.36 18.87 4.22
75 INT32933 Gene_expression of GNAS 2 57 0.32 10.58 4.03
76 INT4075 Positive_regulation of Gene_expression of Gast 2 24 0.68 19.99 4.02
77 INT119053 Positive_regulation of SLC6A3 2 15 0.65 2.51 4
78 INT112782 Localization of Mapk3 2 8 0.78 1.87 3.98
79 INT80175 Positive_regulation of Gene_expression of HRAS 2 24 0.67 14.69 3.97
80 INT70326 Positive_regulation of Gene_expression of ITGB2 4 24 0.67 15.42 3.86
81 INT53706 Positive_regulation of Kras 2 13 0.67 9.26 3.57
82 INT63425 Positive_regulation of Gene_expression of SELP 2 23 0.67 15.34 3.48
83 INT53683 Negative_regulation of Gene_expression of ITGB2 2 10 0.57 9.11 3.2
84 INT15253 Binding of DBH 4 7 0.36 3.21 3.17
85 INT16130 Binding of IGF1 2 67 0.48 27.43 2.95
86 INT59719 Localization of SELP 2 12 0.78 8.4 2.95
87 INT82992 Gene_expression of DRD3 2 3 0.50 2.12 2.88
88 INT15179 Positive_regulation of Gene_expression of SELL 2 18 0.61 14.35 2.84
89 INT147412 Binding of DRD4 4 11 0.47 7.57 2.77
90 INT189863 Gene_expression of DRD4 2 11 0.68 7.65 2.66
91 INT79938 Regulation of Gene_expression of VCAM1 2 12 0.61 11.22 2.64
92 INT163405 Positive_regulation of Binding of ROS1 1 15 0.27 9.39 2.58
93 INT91429 Binding of CD44 12 34 0.41 17.67 2.51
94 INT76713 Regulation of Gene_expression of PECAM1 3 16 0.40 14.52 2.51
95 INT51279 Regulation of IGFBP3 4 17 0.49 15.89 2.45
96 INT101342 Negative_regulation of CYP2A6 4 11 0.53 3.68 2.39
97 INT20991 Regulation of ITGAM 2 9 0.45 5.46 2.27
98 INT99524 Gene_expression of IFIH1 1 34 0.64 23.38 2.24
99 INT103881 Positive_regulation of Binding of DRD2 2 4 0.69 2.01 2.18
100 INT67332 Negative_regulation of ITGA4 2 8 0.51 7.95 2.14
101 INT105008 Binding of DRD3 2 5 0.36 3.15 2.05
102 INT70878 Gene_expression of CYP2A6 4 17 0.75 4.25 2.02
103 INT103244 Protein_catabolism of MMP9 2 12 0.72 11.81 2.01
104 INT173116 Regulation of VCAM1 2 14 0.33 11.85 1.92
105 INT83627 Localization of ITGAM 4 7 0.78 7.26 1.83
106 INT51896 Localization of PECAM1 2 11 0.47 9.8 1.78
107 INT91430 Positive_regulation of CD44 8 25 0.69 15.43 1.76
108 INT78938 Binding of IGFBP3 2 40 0.45 27.95 1.73
109 INT20992 Regulation of ITGB2 2 11 0.37 9.04 1.73
110 INT267108 Negative_regulation of Gene_expression of DRD3 2 2 0.26 1.53 1.69
111 INT78816 Positive_regulation of Positive_regulation of ICAM1 4 9 0.68 8.36 1.55
112 INT179686 Regulation of Gene_expression of COPD 1 10 0.34 14.1 1.52
113 INT93005 Positive_regulation of Binding of ICAM1 2 5 0.68 4.55 1.42
114 INT62824 Negative_regulation of Positive_regulation of ICAM1 2 7 0.53 2.94 1.39
115 INT63339 Transcription of ICAM1 2 6 0.69 3.92 1.37
116 INT56365 Regulation of Gene_expression of ITGB2 1 5 0.60 3.87 1.36
117 INT267107 Binding of CHRNB2 2 2 0.07 1.33 1.25
118 INT100548 Regulation of SELP 4 8 0.29 8.56 1.17
119 INT34056 Regulation of Gene_expression of C6orf25 4 9 0.08 3.86 1.16
120 INT91431 Positive_regulation of Gene_expression of CD44 4 18 0.69 9.25 1.12
121 INT63348 Regulation of PECAM1 6 14 0.40 16.05 0.97
122 INT106386 Regulation of Gene_expression of CD44 4 8 0.27 3.66 0.96
123 INT112783 Regulation of Gene_expression of SELE 2 6 0.40 6.82 0.87
124 INT115964 Negative_regulation of ITGAL 2 7 0.34 3.76 0.86
125 INT84933 Regulation of Gene_expression of SELL 2 8 0.39 5.62 0.84
126 INT101049 Positive_regulation of CD5 2 6 0.67 5.71 0.68
127 INT188775 Binding of IFIH1 1 11 0.16 12.4 0.61
128 INT63356 Regulation of CD44 2 6 0.23 6.29 0.61
129 INT145537 Regulation of Localization of PECAM1 2 3 0.18 4.86 0.59
130 INT267109 Regulation of Binding of MAOA 2 2 0.18 1.15 0.58
131 INT180966 Positive_regulation of Protein_catabolism of COL5A2 2 7 0.06 4.55 0.53
132 INT267147 Regulation of Positive_regulation of SELP 2 2 0.29 3.94 0.42
133 INT171773 Regulation of SELE 2 7 0.23 10.3 0.4
134 INT60035 Regulation of VWF 2 6 0.42 6.26 0.4
135 INT267144 Positive_regulation of Localization of SELP 2 2 0.44 3.79 0.38
136 INT267145 Negative_regulation of Binding of ICAM1 2 5 0.57 4.12 0.33
137 INT267141 Regulation of Binding of PECAM1 2 2 0.18 3.2 0.32
138 INT267142 Phosphorylation of PECAM1 2 2 0.61 2.35 0.27
139 INT267148 Positive_regulation of Phosphorylation of PECAM1 2 2 0.37 2.36 0.27
140 INT267140 Positive_regulation of Localization of ITGAM 2 2 0.25 2.06 0.12
141 INT267150 Regulation of Transcription of ICAM1 2 2 0.26 0.86 0.06
142 INT133317 Positive_regulation of Binding of CD44 4 6 0.55 6.28 0
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