J:Vascular Health and Risk Management

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 1 0.59 9.37 4.48
2 INT66504 Binding of Agt and Agtr1a 8 2 0.39 3.78 1.78
3 INT89379 TNF Positive_regulation of Gene_expression of IL6 5 1 0.50 4.37 1.69
4 INT213071 IL6 Positive_regulation of Gene_expression of CRP 4 2 0.52 6.58 1.68
5 INT108409 AGT Positive_regulation of AGTR2 2 2 0.31 1.49 1.11
6 INT54972 Binding of EDNRA and EDNRB 7 3 0.52 3.31 0.97
7 INT115656 Glp1r Positive_regulation of Localization of Ins1 2 8 0.42 5.23 0.91
8 INT105435 TNF Positive_regulation of IL6 5 1 0.25 4.45 0.83
9 INT332699 Binding of KNG1 and TRGC1 1 2 0.16 3.37 0.75
10 INT213026 Hdl1 Positive_regulation of Nos3 5 3 0.16 7.92 0.73
11 INT202967 MCRS1 Negative_regulation of CPP 2 1 0.14 2.2 0.73
12 INT28947 GH1 Positive_regulation of Gene_expression of IGF1 4 1 0.22 3.78 0.69
13 INT391 Binding of Agt and Ace 2 2 0.33 1.5 0.68
14 INT278827 Binding of EDN1 and EDNRB 3 2 0.17 2.7 0.67
15 INT178097 Binding of EDN1 and EDNRA 7 1 0.21 5.97 0.62
16 INT267625 Binding of KNG1 and Klk1 2 1 0.21 2.23 0.61
17 INT230734 Negative_regulation of Binding of EDNRA and Pah 1 2 0.02 3.26 0.61
18 INT230735 Binding of EDNRA and Pah 1 2 0.02 3.22 0.6
19 INT181619 ACE Positive_regulation of KNG1 1 1 0.33 0.97 0.58
20 INT195666 Binding of PROC and THBD 2 1 0.40 2.42 0.56
21 INT278824 Positive_regulation of Binding of EDNRA and EDNRB 1 3 0.12 1.65 0.53
22 INT278819 EDNRA Negative_regulation of Binding of EDNRA and EDNRB 1 3 0.04 1.65 0.53
23 INT278825 Positive_regulation of Binding of EDN1 and EDNRB 3 2 0.16 1.24 0.49
24 INT344709 Niacr1 Positive_regulation of Hdl1 1 2 0.32 2.74 0.46
25 INT213027 Binding of Apoa1 and Scarb1 6 6 0.09 7.52 0.43
26 INT275156 Agt Positive_regulation of Rac1 1 4 0.03 2.89 0.4
27 INT230724 EDN1 Positive_regulation of EDNRA 3 2 0.24 4.12 0.39
28 INT332701 Binding of BDKRB1 and BDKRB2 1 1 0.01 0.5 0.39
29 INT273617 Gene_expression of Slc6a4 Positive_regulation of Pah 1 1 0.02 0.93 0.38
30 INT78444 Binding of GH1 and IGF1 4 1 0.16 2.82 0.37
31 INT229292 FXR1 Regulation of Gene_expression of FGF19 1 3 0.08 1.14 0.37
32 INT229222 Negative_regulation of ACE Negative_regulation of Protein_catabolism of KNG1 1 1 0.06 0.53 0.37
33 INT332707 Binding of TRGC1 and Klk1 1 1 0.32 1.64 0.36
34 INT278820 EDNRA Negative_regulation of Binding of EDN1 and EDNRB 1 2 0.03 1.1 0.35
35 INT230786 Binding of AGT and ACE 4 3 0.15 2.53 0.34
36 INT4638 Binding of Agt and Adarb1 3 1 0.01 0 0.34
37 INT230855 KNG1 Regulation of NOS1 2 1 0.03 0.94 0.33
38 INT230852 ACE Regulation of KNG1 2 1 0.03 0.72 0.32
39 INT229363 Negative_regulation of Binding of Agt and Agtr1a 2 2 0.22 0.9 0.32
40 INT213062 PTGS1 Regulation of Gene_expression of MMP9 1 1 0.04 0.25 0.3
41 INT265826 Binding of ACE and SERPINE1 1 2 0.24 1.08 0.3
42 INT230752 Gene_expression of Agtr2 Positive_regulation of Gene_expression of Mcpt1 1 2 0.01 1.34 0.3
43 INT239344 Nr1h2 Positive_regulation of Gene_expression of Srebf1 1 1 0.26 0.84 0.29
44 INT230745 Negative_regulation of Ace Negative_regulation of Icam1 1 1 0.05 1.22 0.29
45 INT239324 Nr1h2 Positive_regulation of Hltf 1 1 0.04 0.78 0.29
46 INT239347 Nr1h2 Positive_regulation of Srebf1 1 1 0.26 0.78 0.29
47 INT239329 Nr1h2 Positive_regulation of Gene_expression of Hltf 1 1 0.04 0.84 0.29
48 INT239336 Nr1h2 Positive_regulation of Gene_expression of Fas 1 1 0.07 0.84 0.29
49 INT288911 AGT Positive_regulation of CYBB 3 1 0.07 2.96 0.28
50 INT229332 BAS Negative_regulation of Pck1 1 1 0.01 0.2 0.28
51 INT344704 Positive_regulation of Ppara Positive_regulation of Binding of Hdl1 1 1 0.13 0.83 0.28
52 INT344715 Positive_regulation of Ppara Positive_regulation of Gene_expression of Pltp 1 1 0.02 0.83 0.28
53 INT265831 BGN Positive_regulation of ADCY1 1 1 0.01 0.41 0.27
54 INT230775 CEBPZ Regulation of CPP 1 1 0.11 0.69 0.27
55 INT213029 Positive_regulation of Binding of Apoa1 and Scarb1 1 3 0.09 3.38 0.27
56 INT282647 IL6 Positive_regulation of Gene_expression of F3 1 2 0.00 1.89 0.27
57 INT282648 IL8 Positive_regulation of Gene_expression of F3 1 2 0.00 1.89 0.27
58 INT265830 KNG1 Positive_regulation of Localization of BGN 1 1 0.02 0.33 0.27
59 INT239226 Binding of Edn1 and Ednra 2 1 0.06 1.59 0.26
60 INT282646 Binding of PROC and PROCR 1 1 0.40 0.99 0.26
61 INT282649 Binding of THBD and PROCR 1 1 0.40 0.97 0.26
62 INT239335 Eef1a2 Positive_regulation of Ppara 1 1 0.27 0.57 0.26
63 INT242215 Binding of ANG and OLR1 1 2 0.02 1.63 0.25
64 INT256227 Binding of EDN1 and VEGFA 1 2 0.18 2.92 0.25
65 INT239238 Ace Positive_regulation of Protein_catabolism of KNG1 1 1 0.01 0.46 0.24
66 INT239337 Abca1 Positive_regulation of RCT 1 3 0.07 3.11 0.24
67 INT230748 Agtr2 Positive_regulation of Gene_expression of Ros1 2 1 0.05 1.04 0.23
68 INT344714 Nr1h4 Negative_regulation of Gene_expression of Lipg 1 1 0.02 0.77 0.23
69 INT230751 Agtr2 Positive_regulation of Gene_expression of Serpine1 1 1 0.03 1.3 0.23
70 INT213061 PTGER2 Regulation of Gene_expression of MMP9 1 1 0.03 0.25 0.23
71 INT265886 IGF1 Positive_regulation of AKT1 1 3 0.11 3.06 0.23
72 INT255044 GLP1R Positive_regulation of Localization of INS 3 1 0.49 1.47 0.22
73 INT265828 ACE Regulation of Gene_expression of KNG1 1 1 0.32 0.83 0.22
74 INT332700 Binding of F12 and KNG1 1 1 0.15 1.05 0.21
75 INT242245 Binding of P2ry1 and Adp 1 1 0.00 0.31 0.21
76 INT288854 Binding of PTGDR and PHGDH 1 1 0.00 1.04 0.21
77 INT242250 Binding of P2ry1 and P2ry12 1 1 0.01 0.3 0.21
78 INT242244 Binding of P2ry12 and Adp 1 1 0.00 0.31 0.21
79 INT229360 Agt Positive_regulation of Agtr1a 2 1 0.48 1.26 0.2
80 INT285979 Ros1 Positive_regulation of Trib3 2 1 0.02 2.18 0.2
81 INT239236 Prkca Regulation of CYBB 1 1 0.00 0.98 0.2
82 INT284519 NOVA2 Positive_regulation of Gene_expression of CX3CL1 1 1 0.07 1.49 0.2
83 INT239235 Prkca Positive_regulation of Prkca Regulation of Nos3 1 1 0.01 0.97 0.2
84 INT275159 Agt Positive_regulation of Phosphorylation of Stat3 1 2 0.04 1.44 0.2
85 INT239328 Hdl1 Regulation of Gene_expression of Kitl 1 1 0.08 1.86 0.2
86 INT239227 Prkca Regulation of Nos3 1 1 0.02 0.97 0.2
87 INT230749 Crp Regulation of Agtr1a 1 1 0.07 1.33 0.19
88 INT300193 Binding of APOA1 and INSL4 1 2 0.01 2.17 0.18
89 INT278817 EDNRA Negative_regulation of Binding of EDN1 and EDNRA 1 1 0.02 0.55 0.18
90 INT239316 Nr1h2 Positive_regulation of Transcription of Abca1 1 1 0.15 0.67 0.18
91 INT278818 EDNRA Negative_regulation of Binding of EDNRB and EDNRB 1 1 0.06 0.55 0.18
92 INT229223 Binding of AGT and FAS 1 1 0.08 0.91 0.17
93 INT229245 Positive_regulation of Binding of FAS and Tnf 1 1 0.25 0.92 0.17
94 INT213072 Binding of IFNA1 and ACCS 1 1 0.06 3.85 0.17
95 INT213041 Hdl1 Negative_regulation of Gene_expression of Vcam1 1 1 0.14 0.9 0.17
96 INT229246 Binding of FAS and Tnf 1 1 0.19 0.91 0.17
97 INT229224 Positive_regulation of Binding of AGT and FAS 1 1 0.09 0.92 0.17
98 INT265827 ACE Negative_regulation of ANGPT2 1 1 0.09 0.59 0.17
99 INT265892 IGF1 Positive_regulation of PIK3CG 1 2 0.18 1.96 0.16
100 INT229289 FGF19 Negative_regulation of CYP7A1 1 1 0.26 0.32 0.16
101 INT278828 Positive_regulation of Binding of EDN1 and EDNRA 1 1 0.06 0.51 0.15
102 INT240768 Binding of F2 and F13A1 1 2 0.07 2.25 0.15
103 INT241177 Abl2 Regulation of Cat 1 2 0.14 0.3 0.15
104 INT344721 Binding of AHA and Hdl1 1 1 0.02 1.16 0.15
105 INT213010 Hdl1 Negative_regulation of Gene_expression of Icam1 1 1 0.15 1.01 0.15
106 INT213005 Hdl1 Positive_regulation of Akt1 3 3 0.19 3.81 0.14
107 INT239317 Egfl7 Positive_regulation of Hdl1 2 2 0.01 2.3 0.14
108 INT344707 Scarb1 Positive_regulation of Positive_regulation of Hdl1 1 1 0.14 0.88 0.14
109 INT239323 Binding of Nr1h2 and Positive_regulation of Positive_regulation of Tgfb1 1 3 0.00 3.71 0.14
110 INT344710 Lipc Positive_regulation of Positive_regulation of Hdl1 1 1 0.04 0.87 0.14
111 INT239355 Binding of Nr1h2 and Positive_regulation of Gene_expression of CETP 1 3 0.17 3.75 0.14
112 INT265956 Clas4 Regulation of PPARA 1 2 0.01 0.7 0.14
113 INT332689 Binding of Edn1 and Ros1 1 1 0.08 0.71 0.14
114 INT229290 BAS Negative_regulation of LDLR 1 1 0.03 0.83 0.13
115 INT267973 Binding of CHKB and ESR1 1 1 0.02 1.67 0.13
116 INT241167 Binding of TNXA and Serpinc1 1 1 0.00 0.43 0.13
117 INT239339 Hdl1 Negative_regulation of Gene_expression of Paf 1 1 0.02 1.43 0.13
118 INT230761 VEGFA Positive_regulation of Kdr 2 1 0.02 2.16 0.12
119 INT344705 Nr1h2 Regulation of Scarb1 1 2 0.04 1.53 0.12
120 INT270723 Negative_regulation of HMGCR Positive_regulation of LDLR 1 1 0.02 0.52 0.12
121 INT344706 Nr1h2 Regulation of Abca1 1 3 0.03 2.39 0.12
122 INT230760 VEGFA Positive_regulation of Flt1 1 1 0.03 0.96 0.12
123 INT267927 asa Negative_regulation of Gene_expression of Tbxa2r 1 1 0.00 0.78 0.12
124 INT213144 TIMP1 Negative_regulation of THBD 1 1 0.04 1.16 0.12
125 INT332687 Ros1 Positive_regulation of Crk 1 1 0.17 0.77 0.12
126 INT344713 Nr1h2 Regulation of Abcg1 1 3 0.03 2.39 0.12
127 INT213147 DAK Negative_regulation of THBD 1 1 0.00 1.16 0.12
128 INT213058 Binding of Apoa1 and Scarb1 Positive_regulation of Positive_regulation of Hdl1 1 1 0.05 1.15 0.12
129 INT332685 Trib3 Positive_regulation of Binding of Ros1 1 1 0.01 0.74 0.12
130 INT229359 Agt Positive_regulation of Binding of Agtr1a 1 1 0.25 0.9 0.12
131 INT213042 Apoa1 Positive_regulation of Nos3 1 2 0.10 2.17 0.11
132 INT270746 INS Regulation of LEP 1 1 0.07 0.72 0.11
133 INT229364 Ace Positive_regulation of Protein_catabolism of KNG1 1 1 0.02 0.86 0.11
134 INT265919 Binding of PLEK and Adp 1 1 0.01 0.38 0.11
135 INT229287 BAS Negative_regulation of CRP 1 2 0.04 0.36 0.11
136 INT297938 Binding of ICAM1 and PAOD1 1 1 0.06 0.86 0.11
137 INT275171 Binding of Stat3 and Rac1 Positive_regulation of Rac1 Positive_regulation of Stat3 1 1 0.01 0.73 0.1
138 INT265888 BCL2 Regulation of Gene_expression of BAD 1 1 0.04 1.08 0.1
139 INT265890 BCL2 Regulation of Gene_expression of BAX 1 1 0.04 1.08 0.1
140 INT265889 BAX Regulation of Gene_expression of BAD 1 1 0.06 1.08 0.1
141 INT332637 Negative_regulation of Dpp4 Negative_regulation of Localization of Ins1 1 2 0.06 1.66 0.1
142 INT242203 GLP1R Regulation of GCG 1 1 0.04 0.64 0.1
143 INT242204 DPP4 Positive_regulation of Gene_expression of GLP1R 1 1 0.03 0.66 0.1
144 INT275157 Binding of Stat3 and Rac1 1 1 0.05 0.71 0.1
145 INT213053 Hdl1 Negative_regulation of Gene_expression of Adamts1 1 1 0.07 0.88 0.1
146 INT275158 Rac1 Positive_regulation of Stat3 1 1 0.07 0.72 0.1
147 INT267684 Binding of INS and ARID1B 3 1 0.10 6.08 0.09
148 INT239643 Binding of BCL2 and BCL2L11 3 1 0.16 2.26 0.09
149 INT164925 GIP Positive_regulation of Localization of INS 2 1 0.59 0.86 0.09
150 INT213023 Hdl1 Regulation of Nos3 2 1 0.09 4.06 0.09
151 INT270731 Binding of AGTR1 and ACE 1 1 0.02 0.67 0.09
152 INT332688 Ros1 Positive_regulation of Binding of Edn1 1 1 0.10 0.57 0.09
153 INT230857 Negative_regulation of Binding of HSP90AA1 and NOS1 1 1 0.05 1.18 0.09
154 INT230750 Crp Positive_regulation of Edn1 1 1 0.10 0.27 0.09
155 INT282102 Binding of Crp and Vcam1 1 1 0.00 1.55 0.09
156 INT265887 IGF1 Negative_regulation of BCL2 1 1 0.09 1.02 0.09
157 INT229286 BAS Negative_regulation of FXR1 1 1 0.02 0.55 0.09
158 INT265878 IGF1 Negative_regulation of Binding of BCL2 and BCL2L11 1 1 0.03 1.03 0.09
159 INT213006 Olr1 Positive_regulation of Gene_expression of Mmp9 1 1 0.11 0.81 0.09
160 INT265829 ACE Positive_regulation of Protein_catabolism of KNG1 1 1 0.33 0.73 0.09
161 INT230856 Binding of HSP90AA1 and NOS1 1 1 0.04 1.17 0.09
162 INT213145 DAK Positive_regulation of TIMP1 1 1 0.02 0.36 0.09
163 INT213051 Hdl1 Positive_regulation of Pik3r1 1 2 0.13 1.93 0.09
164 INT213018 Hdl1 Negative_regulation of Gene_expression of Mmp9 1 1 0.10 0.81 0.09
165 INT229274 BAS Positive_regulation of BAS Negative_regulation of FXR1 1 1 0.00 0.55 0.09
166 INT230746 Crp Positive_regulation of Localization of Serpine1 1 1 0.16 0.27 0.09
167 INT242257 Binding of EDN1 and ELF3 1 1 0.17 0.21 0.08
168 INT300192 Gene_expression of APOA1 Positive_regulation of HSD11B1 1 1 0.16 1.08 0.08
169 INT213239 Binding of TNXA and Serpinc1 1 1 0.00 0.16 0.08
170 INT239237 TCN2 Positive_regulation of Gene_expression of Serpine1 1 1 0.00 0.68 0.08
171 INT267969 Binding of AGT and TRPV1 1 1 0.00 0.44 0.08
172 INT267970 Negative_regulation of Binding of AGT and TRPV1 1 1 0.00 0.44 0.08
173 INT229330 Binding of Nr1h2 and Positive_regulation of Gene_expression of GCK 1 1 0.01 0.62 0.07
174 INT229333 Binding of Nr1h2 and Positive_regulation of Gene_expression of SLC2A4 1 1 0.02 0.62 0.07
175 INT242258 ELF3 Negative_regulation of EDN1 1 1 0.15 0.09 0.07
176 INT273616 PVR Positive_regulation of Pah 1 1 0.10 0.86 0.07
177 INT332639 Glp1r Negative_regulation of Localization of Gcg 1 2 0.03 0.87 0.07
178 INT265883 IGF1 Positive_regulation of Transcription of FOXO1 1 1 0.17 1.14 0.07
179 INT239346 Olfr642 Positive_regulation of Lcat 1 1 0.00 1.06 0.07
180 INT230853 Binding of SELE and VWF 1 1 0.06 1.3 0.07
181 INT265882 IGF1 Positive_regulation of Transcription of AKT1 1 1 0.08 1.13 0.07
182 INT265877 IGF1 Regulation of Binding of GH1 and IGF1 1 1 0.03 0.47 0.07
183 INT213019 Hdl1 Positive_regulation of Tgoln1 1 1 0.03 1.01 0.07
184 INT230883 Binding of IGHE and tryptase 1 1 0.01 0.23 0.07
185 INT265893 BAD Regulation of FOXO1 1 1 0.03 1.08 0.06
186 INT229291 BAS Positive_regulation of HSD11B1 1 1 0.09 0.22 0.06
187 INT267998 Binding of XDH and Nos1 1 1 0.02 0.46 0.06
188 INT213261 TNF Positive_regulation of CRP 1 1 0.24 1.59 0.06
189 INT213001 Hdl1 Positive_regulation of Trib3 1 2 0.00 2 0.06
190 INT239327 Positive_regulation of Binding of Lcat and Hdl1 1 1 0.06 1.52 0.06
191 INT239331 RCT Positive_regulation of Lcat 1 1 0.08 1.08 0.06
192 INT239354 CETP Positive_regulation of Lcat 1 1 0.28 1.09 0.06
193 INT239326 Binding of Lcat and Hdl1 1 1 0.05 1.52 0.06
194 INT267923 Negative_regulation of Dpp4 Positive_regulation of Glp1r 1 1 0.00 0.23 0.05
195 INT332641 Binding of PPARG and Ins1 1 1 0.12 1.05 0.05
196 INT332631 Negative_regulation of Dpp4 Negative_regulation of Gcg 1 1 0.05 1 0.05
197 INT213060 Hdl1 Negative_regulation of Gene_expression of PLEK 1 1 0.25 1.33 0.05
198 INT344719 Hdl1 Positive_regulation of Plat 1 1 0.10 1.23 0.05
199 INT239318 Binding of Cor and Hdl1 1 1 0.07 1.69 0.05
200 INT213014 Regulation of Hdl1 Positive_regulation of Akt1 1 1 0.12 0.97 0.05

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 38 3152 0.78 2515.62 929.82
2 INT9238 Gene_expression of IL6 13 1575 0.78 1135.66 424.22
3 INT5235 Negative_regulation of TNF 8 924 0.59 772.91 331.98
4 INT5059 Positive_regulation of TNF 10 1050 0.70 896.51 322.81
5 INT9131 Positive_regulation of Prkcg 2 431 0.70 130.8 302.41
6 INT63932 Positive_regulation of Ephb1 1 537 0.70 259.67 296.14
7 INT1352 Localization of Acot1 1 728 0.80 73.01 296.01
8 INT9158 Gene_expression of Tnf 1 722 0.78 522.01 277.68
9 INT6852 Localization of TNF 8 883 0.81 705.95 270.84
10 INT10832 Gene_expression of IL8 3 1050 0.78 698.72 270
11 INT9659 Gene_expression of Il6 2 991 0.78 715.11 265.57
12 INT5972 Gene_expression of IL1B 5 948 0.78 510.91 263.97
13 INT68684 Gene_expression of VEGFA 2 2371 0.78 1742.52 259.2
14 INT87687 Positive_regulation of Trpv1 1 409 0.70 210.24 257.59
15 INT16868 Gene_expression of Il6 1 807 0.78 499.48 256.57
16 INT6481 Binding of TNF 6 624 0.48 510.2 214.82
17 INT6482 Positive_regulation of Gene_expression of TNF 9 659 0.70 569.88 210
18 INT9132 Negative_regulation of Prkcg 3 279 0.59 88.05 203.47
19 INT10194 Positive_regulation of IL6 6 702 0.70 600.62 183.38
20 INT19472 Gene_expression of Il1 1 554 0.76 419.75 175.35
21 INT15516 Gene_expression of Crp 25 711 0.77 615.33 173.09
22 INT867 Gene_expression of IFNA1 7 930 0.78 594.85 168.03
23 INT55879 Gene_expression of CCL2 1 421 0.78 240.74 166.02
24 INT1114 Localization of Ins1 2 748 0.80 192.95 165.48
25 INT66280 Gene_expression of Nos2 3 534 0.78 330.78 157.07
26 INT15515 Positive_regulation of Crp 17 700 0.70 604.24 150.15
27 INT13353 Positive_regulation of Tnf 1 332 0.70 248.75 148.1
28 INT1033 Positive_regulation of Ca2 2 507 0.68 131.76 147.64
29 INT9852 Positive_regulation of Gpt 8 563 0.70 364.64 146.82
30 INT812 Localization of INS 84 1026 0.81 515.6 145.31
31 INT64161 Positive_regulation of Prkca 6 213 0.70 85.06 129.91
32 INT115386 Gene_expression of Ppara 3 779 0.77 549.99 128.36
33 INT4259 Positive_regulation of Npr1 3 262 0.70 49.37 123.11
34 INT252 Localization of GH1 8 529 0.80 227.4 122.05
35 INT17612 Gene_expression of CRP 24 676 0.78 580.61 119.03
36 INT62124 Gene_expression of NOS1 8 444 0.78 218.08 114.85
37 INT48593 Positive_regulation of NOS1 4 420 0.68 226.15 114.71
38 INT11051 Positive_regulation of Gene_expression of IL6 2 415 0.69 319.21 109.3
39 INT47243 Gene_expression of Prkcg 4 195 0.78 58.05 108.44
40 INT60526 Gene_expression of IL10 4 449 0.78 292.71 107.84
41 INT3038 Gene_expression of INS 244 1583 0.78 1174.16 107.01
42 INT12082 Localization of IL6 4 365 0.81 241.78 105.78
43 INT49171 Gene_expression of Nos1 3 241 0.78 140.7 104.76
44 INT69440 Gene_expression of ROS1 9 752 0.78 477.64 103.83
45 INT18009 Positive_regulation of CRP 10 518 0.70 553.03 103.74
46 INT11381 Positive_regulation of IL1B 1 330 0.70 209.31 100.9
47 INT1760 Gene_expression of PTGER2 3 524 0.57 226.94 96.4
48 INT940 Negative_regulation of Ptgs1 1 219 0.59 104.34 95.97
49 INT86024 Gene_expression of PPARA 12 736 0.78 497.93 91.14
50 INT48767 Negative_regulation of NOS1 3 312 0.59 154.25 90.32
51 INT12763 Phosphorylation of Prkcg 2 167 0.82 38.91 89.63
52 INT96917 Positive_regulation of Mapk14 1 261 0.70 173.29 88.79
53 INT64158 Negative_regulation of Prkca 2 121 0.59 29.8 88.66
54 INT48408 Gene_expression of ICAM1 10 494 0.78 340.08 88.6
55 INT1635 Gene_expression of Vip 2 245 0.78 53.36 88.13
56 INT7180 Negative_regulation of Trib3 1 180 0.51 68.48 88.01
57 INT1472 Positive_regulation of Ins1 3 349 0.69 146.2 86.36
58 INT914 Positive_regulation of GH1 1 292 0.69 100.7 84.91
59 INT84546 Positive_regulation of Ppara 8 481 0.70 334.21 83.45
60 INT68682 Positive_regulation of VEGFA 1 640 0.70 454.14 81.65
61 INT56291 Gene_expression of Ros1 10 503 0.63 274.12 81.5
62 INT10534 Positive_regulation of Trib3 1 209 0.60 78.75 81.48
63 INT3214 Localization of Ins1 39 527 0.80 196.9 79.26
64 INT9382 Regulation of TRPV1 1 149 0.62 53.99 77.46
65 INT3657 Gene_expression of Ins1 12 514 0.78 321.69 75.76
66 INT1724 Negative_regulation of ACE 83 437 0.59 315.64 74.48
67 INT12536 Localization of Prkcg 1 101 0.80 36.37 73.81
68 INT9236 Regulation of Gene_expression of TNF 1 204 0.62 162.66 72.99
69 INT58400 Negative_regulation of Tnf 1 182 0.59 129.97 71
70 INT15913 Negative_regulation of CYP2D6 3 174 0.59 22.45 70.91
71 INT10837 Positive_regulation of Gene_expression of IL8 3 294 0.70 190.08 70.34
72 INT79494 Positive_regulation of Gene_expression of VEGFA 1 577 0.70 442.94 69.73
73 INT6849 Localization of IL1B 1 229 0.81 112.56 69.63
74 INT8357 Gene_expression of KNG1 5 153 0.75 77.26 68.66
75 INT7534 Gene_expression of Ifng 2 193 0.78 111.02 68.6
76 INT39777 Regulation of Prkcg 1 90 0.62 31.52 68.17
77 INT7134 Localization of KNG1 2 127 0.79 65.73 67.97
78 INT102546 Gene_expression of Ccl2 6 197 0.78 192.8 67.41
79 INT5374 Gene_expression of Esr1 2 412 0.77 263.89 67.34
80 INT13286 Gene_expression of Ca2 1 317 0.67 71.58 65.01
81 INT1599 Positive_regulation of ADCY1 1 146 0.67 30.05 64.9
82 INT15514 Negative_regulation of Crp 33 275 0.59 194.6 64.86
83 INT822 Gene_expression of ESR1 1 529 0.78 302.16 63.64
84 INT67614 Positive_regulation of PPARA 7 438 0.68 293.28 63.61
85 INT46 Localization of Ren 2 233 0.81 46.15 62.44
86 INT17401 Gene_expression of IGF1 16 475 0.78 232.18 62.07
87 INT11318 Gene_expression of Gtf3a 2 274 0.52 183.82 60.89
88 INT5058 Positive_regulation of IFNA1 1 356 0.70 245.75 60.52
89 INT9196 Gene_expression of PTGS1 1 215 0.77 96.99 60.5
90 INT17564 Gene_expression of Gpt 4 322 0.75 208.51 60.36
91 INT103924 Positive_regulation of Akt1 4 359 0.69 158.94 60.34
92 INT14740 Gene_expression of TGFB1 1 272 0.78 168.48 60.18
93 INT546 Binding of ALB 2 311 0.48 85.98 60.14
94 INT55344 Gene_expression of Ros1 3 396 0.54 217.64 59.98
95 INT1759 Gene_expression of TIMP1 10 267 0.77 133.87 59.29
96 INT11491 Positive_regulation of KNG1 15 128 0.67 60.41 58.74
97 INT82055 Positive_regulation of Creb1 1 176 0.70 60.2 58.39
98 INT48901 Negative_regulation of IL6 3 186 0.57 136.33 57.87
99 INT73048 Gene_expression of MMP9 3 268 0.77 159.75 57.81
100 INT9408 Positive_regulation of Crp 6 296 0.69 242.27 57.35
101 INT1200 Negative_regulation of Ins1 1 274 0.58 155.17 56.14
102 INT96937 Gene_expression of Mmp9 1 191 0.75 150.3 56.01
103 INT64159 Gene_expression of Prkca 1 90 0.78 34.65 55.97
104 INT314 Positive_regulation of Ren 4 212 0.70 66.68 55.56
105 INT251 Regulation of INS 52 398 0.62 232.47 55.04
106 INT2276 Regulation of Ins1 3 234 0.61 103.78 54.05
107 INT3213 Gene_expression of Ins1 18 511 0.76 357.59 53.32
108 INT96914 Phosphorylation of Mapk14 1 168 0.82 108.46 53.32
109 INT9234 Negative_regulation of Gene_expression of IL6 2 171 0.59 101.61 53.15
110 INT62543 Gene_expression of Icam1 7 231 0.78 187.58 52.71
111 INT22112 Positive_regulation of Localization of TNF 2 164 0.70 115.66 52.18
112 INT72182 Gene_expression of Mcpt1 6 167 0.75 123.7 52.15
113 INT249 Localization of GHRH 2 215 0.80 78.02 51.87
114 INT50334 Negative_regulation of Cnr1 1 84 0.58 30.86 51.75
115 INT64110 Positive_regulation of Gene_expression of Nos1 4 68 0.70 58.11 51.64
116 INT83199 Gene_expression of Nos3 2 193 0.78 100.72 51.57
117 INT50405 Negative_regulation of CYP3A4 7 238 0.59 53.65 51.51
118 INT122041 Binding of Ppara 1 308 0.48 189.17 51.48
119 INT6473 Positive_regulation of Gene_expression of IL1B 1 204 0.70 117.23 50.86
120 INT1199 Positive_regulation of INS 78 579 0.70 399.64 50.43
121 INT2604 Positive_regulation of Got1 8 223 0.70 154.78 49.51
122 INT22454 Regulation of Crp 2 213 0.62 160.67 49.24
123 INT4345 Gene_expression of Gtf3a 3 157 0.67 80.75 48.47
124 INT7093 Negative_regulation of CYP2B6 1 146 0.58 37.3 48.39
125 INT17881 Gene_expression of LEP 20 278 0.78 221.61 48.31
126 INT66029 Negative_regulation of Tnf 1 100 0.59 84.28 48.16
127 INT654 Localization of REN 21 250 0.81 75.12 47.86
128 INT106525 Phosphorylation of Akt1 4 436 0.82 183.81 47.82
129 INT671 Positive_regulation of Cea 2 221 0.69 164.5 47.79
130 INT375 Positive_regulation of REN 27 293 0.70 152.46 47.55
131 INT48718 Positive_regulation of PRKCA 5 109 0.69 36.16 46.49
132 INT531 Gene_expression of GH1 9 376 0.75 193.45 46.24
133 INT71786 Phosphorylation of MAPK1 1 256 0.82 110.09 46.17
134 INT5781 Gene_expression of Edn1 4 190 0.78 99.1 46
135 INT1322 Positive_regulation of Localization of INS 27 293 0.70 120.86 45.98
136 INT2275 Negative_regulation of Localization of Ins1 2 183 0.59 51.02 44.94
137 INT1726 Positive_regulation of Kitl 2 65 0.70 38.81 44.85
138 INT3361 Positive_regulation of Esr1 2 273 0.69 208.53 44.81
139 INT80124 Negative_regulation of VEGFA 3 450 0.58 311.19 44.53
140 INT98498 Binding of Trpv1 1 75 0.48 33.67 44.4
141 INT2774 Binding of Crp 5 241 0.48 195.89 44.39
142 INT1474 Regulation of Localization of Ins1 1 132 0.61 25.96 43.07
143 INT49105 Gene_expression of Vcam1 1 157 0.78 157.27 43.01
144 INT613 Gene_expression of Alb 3 268 0.78 149.84 42.78
145 INT65245 Gene_expression of Nos3 6 121 0.78 98.14 41.56
146 INT11939 Negative_regulation of Il6 3 138 0.59 87.46 41.24
147 INT69437 Positive_regulation of ROS1 3 328 0.58 222.83 40.56
148 INT52732 Negative_regulation of CRP 11 169 0.59 138.47 40.33
149 INT3987 Positive_regulation of IGHE 2 316 0.70 283.2 40.16
150 INT3252 Negative_regulation of INS 43 428 0.59 271.65 39.52
151 INT11560 Positive_regulation of CASP3 2 236 0.70 184.33 39.38
152 INT47939 Gene_expression of Selp 3 171 0.76 87.54 39.03
153 INT77434 Positive_regulation of Gene_expression of Nos2 4 151 0.69 96.76 38.94
154 INT3758 Gene_expression of ALB 3 326 0.78 184.65 38.75
155 INT9094 Gene_expression of COL7A1 5 277 0.77 143.42 38.73
156 INT68975 Gene_expression of Mmp9 2 111 0.78 79.57 38.55
157 INT385 Gene_expression of Agt 9 182 0.78 63.62 37.91
158 INT63349 Gene_expression of PECAM1 6 199 0.75 166.03 36.76
159 INT9082 Positive_regulation of ESR1 1 238 0.69 148.51 36.69
160 INT3253 Negative_regulation of Localization of INS 10 205 0.59 130.39 36.61
161 INT12892 Negative_regulation of TIMP1 2 136 0.58 83.13 36.54
162 INT62827 Positive_regulation of ICAM1 2 184 0.70 180.95 36.28
163 INT390 Positive_regulation of Agt 13 170 0.70 61.47 36.08
164 INT3216 Positive_regulation of Localization of Ins1 20 170 0.69 56.78 35.63
165 INT13501 Binding of Drd2 1 65 0.48 23.76 35.6
166 INT255 Regulation of Localization of GH1 3 89 0.62 18.71 35.3
167 INT3679 Gene_expression of AVP 2 171 0.78 72.9 35.23
168 INT60710 Gene_expression of Col7a1 1 217 0.78 113.2 35.2
169 INT8747 Positive_regulation of Ins1 8 221 0.69 154.28 35.15
170 INT6484 Binding of IL1B 1 122 0.47 75.84 35.07
171 INT2274 Regulation of Localization of INS 1 101 0.62 41.55 34.79
172 INT103094 Binding of PPARA 7 308 0.47 177.26 34.75
173 INT12765 Positive_regulation of Phosphorylation of Prkcg 1 59 0.66 20.16 34.67
174 INT7675 Gene_expression of ENG 1 146 0.77 45.35 34.6
175 INT18893 Positive_regulation of CPP 4 81 0.69 38.03 34.33
176 INT8905 Gene_expression of EDN1 34 215 0.78 157.1 34.19
177 INT17381 Gene_expression of Tbxa2r 14 146 0.78 65.01 34.15
178 INT74563 Positive_regulation of Gene_expression of ROS1 2 258 0.61 168.18 34.08
179 INT16960 Gene_expression of Crp 6 166 0.76 116.21 34.07
180 INT11764 Positive_regulation of ENG 1 78 0.61 27.65 33.69
181 INT234 Binding of Alb 4 151 0.48 52.34 32.97
182 INT9658 Negative_regulation of Gene_expression of Il6 1 110 0.59 66.29 32.58
183 INT62830 Gene_expression of VCAM1 4 149 0.78 125.23 32.4
184 INT985 Negative_regulation of GH1 4 213 0.57 89.53 32.39
185 INT96913 Positive_regulation of Mapk8 2 179 0.69 130.44 32.2
186 INT29503 Gene_expression of Mmp2 1 95 0.77 56.92 31.68
187 INT1159 Negative_regulation of Agt 6 133 0.59 40.14 31.67
188 INT608 Negative_regulation of KNG1 4 98 0.43 72.36 31.23
189 INT65960 Gene_expression of BCL2 1 352 0.78 312.03 30.73
190 INT151111 Gene_expression of Pain1 3 33 0.40 33.6 30.73
191 INT2884 Positive_regulation of CCK 1 66 0.69 25.25 30.6
192 INT1179 Negative_regulation of Ace 27 157 0.59 67.03 30.46
193 INT72923 Positive_regulation of MCRS1 8 72 0.50 99.19 30.36
194 INT1158 Regulation of Agt 2 106 0.61 29.4 30.29
195 INT50 Negative_regulation of Localization of Ren 1 87 0.59 14.94 30.22
196 INT68973 Positive_regulation of Mmp9 1 89 0.52 58.56 30.04
197 INT724 Negative_regulation of Alb 1 151 0.59 93.57 29.65
198 INT660 Negative_regulation of REN 34 194 0.59 82.06 29.46
199 INT9650 Gene_expression of LPA 7 141 0.75 104.57 29
200 INT9199 Positive_regulation of CEBPZ 15 111 0.67 30.99 28.45
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