J:World J. Gastroenterol.

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT102599 Binding of EXOSC3 and TPPP3 3 2 0.39 2.61 0.48
2 INT139563 Tlr4 Positive_regulation of Localization of IL18 1 1 0.01 0 0
3 INT115239 Binding of Casp1 and EXOSC3 1 1 0.40 0.11 0
4 INT115240 Binding of Casp1 and TPPP3 1 1 0.52 0.11 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT5200 Gene_expression of Fos 14 3083 0.78 894.43 1639.02
2 INT796 Gene_expression of Penk 1 1902 0.78 275.47 1057.59
3 INT6483 Gene_expression of TNF 1 3152 0.78 2515.62 929.82
4 INT1912 Gene_expression of Calca 8 1152 0.78 453.25 739.84
5 INT5202 Positive_regulation of Gene_expression of Fos 2 1163 0.70 319.28 684
6 INT58061 Gene_expression of Trpv1 1 1117 0.78 451.54 637.59
7 INT728 Positive_regulation of Penk 1 1068 0.70 186.9 636.87
8 INT797 Regulation of Penk 2 812 0.62 111.13 542.24
9 INT50058 Negative_regulation of Cpox 1 907 0.58 426.28 428.29
10 INT6056 Negative_regulation of Gene_expression of Fos 2 601 0.59 193.05 386.84
11 INT34869 Negative_regulation of PTGS2 4 778 0.59 366.76 319.85
12 INT9158 Gene_expression of Tnf 1 722 0.78 522.01 277.68
13 INT5591 Regulation of Gene_expression of Fos 1 425 0.62 129.06 265.78
14 INT68684 Gene_expression of VEGFA 5 2371 0.78 1742.52 259.2
15 INT16868 Gene_expression of Il6 1 807 0.78 499.48 256.57
16 INT3948 Regulation of Cck 1 291 0.62 58.07 255.88
17 INT5597 Gene_expression of Pdyn 2 433 0.78 62.97 235.47
18 INT6482 Positive_regulation of Gene_expression of TNF 1 659 0.70 569.88 210
19 INT4803 Transcription of Penk 1 435 0.72 59.09 182.4
20 INT943 Negative_regulation of Cck 1 205 0.59 38.42 174.78
21 INT438 Gene_expression of Crh 5 376 0.78 159.11 169.17
22 INT867 Gene_expression of IFNA1 2 930 0.78 594.85 168.03
23 INT2366 Binding of Cck 1 192 0.48 30.64 163.46
24 INT51921 Gene_expression of Cpox 1 501 0.73 229.81 157.81
25 INT4740 Gene_expression of Th 5 298 0.78 61.27 154.03
26 INT13353 Positive_regulation of Tnf 2 332 0.70 248.75 148.1
27 INT3300 Positive_regulation of Gene_expression of Calca 1 179 0.70 77.76 144.2
28 INT60126 Regulation of Trpv1 1 186 0.62 85.53 133.4
29 INT5497 Positive_regulation of Crh 1 299 0.70 125.54 131.14
30 INT5595 Positive_regulation of Pdyn 1 223 0.70 48.37 130.14
31 INT64161 Positive_regulation of Prkca 2 213 0.70 85.06 129.91
32 INT4824 Positive_regulation of Tacr1 2 169 0.70 66.1 123.46
33 INT14151 Gene_expression of Casp3 7 311 0.78 140.26 120.68
34 INT50674 Gene_expression of PTGS2 3 459 0.78 253.33 118.51
35 INT18009 Positive_regulation of CRP 1 518 0.70 553.03 103.74
36 INT1898 Regulation of Crh 6 220 0.62 61.33 102.64
37 INT89054 Positive_regulation of Gene_expression of Trpv1 1 156 0.70 90.78 102.03
38 INT64158 Negative_regulation of Prkca 1 121 0.59 29.8 88.66
39 INT1635 Gene_expression of Vip 4 245 0.78 53.36 88.13
40 INT15898 Positive_regulation of Prkaca 1 199 0.70 50.89 87.54
41 INT5594 Regulation of Pdyn 2 137 0.62 27.04 86.63
42 INT5780 Regulation of Gene_expression of Calca 1 90 0.62 59.52 85.03
43 INT4830 Binding of Trpv1 4 158 0.48 45.11 84.2
44 INT5590 Negative_regulation of Fos 1 144 0.59 40.94 81.98
45 INT2431 Positive_regulation of Mpo 2 275 0.70 211.99 78.47
46 INT5374 Gene_expression of Esr1 1 412 0.77 263.89 67.34
47 INT66531 Gene_expression of Pnoc 1 88 0.78 22.9 65.11
48 INT52692 Gene_expression of Ptgs2 2 160 0.78 85.06 55.73
49 INT1486 Negative_regulation of Cpe 1 85 0.59 28.78 54.08
50 INT49993 Positive_regulation of Gene_expression of Il6 1 149 0.70 88.07 53.78
51 INT22546 Positive_regulation of Gene_expression of Casp3 1 97 0.70 47.89 51.92
52 INT35975 Regulation of Cpox 1 109 0.39 57.88 49.69
53 INT3361 Positive_regulation of Esr1 1 273 0.69 208.53 44.81
54 INT8465 Regulation of Ptgs1 1 100 0.57 36.03 44.41
55 INT8824 Regulation of Vip 2 95 0.62 15.7 43.63
56 INT5502 Positive_regulation of Gene_expression of Crh 4 69 0.70 43.06 42.23
57 INT64440 Gene_expression of Pnoc 1 66 0.78 13.61 41.76
58 INT66532 Positive_regulation of Pnoc 2 46 0.70 14.99 41.39
59 INT350 Localization of Th 1 79 0.80 10.26 41.17
60 INT2429 Negative_regulation of Mpo 1 128 0.59 93.76 39.57
61 INT55135 Positive_regulation of Gene_expression of PTGS2 1 137 0.70 80.32 38.46
62 INT1624 Gene_expression of Cea 1 212 0.76 180.44 34.21
63 INT7286 Regulation of Transcription of Penk 1 81 0.62 9.25 33.45
64 INT99688 Negative_regulation of Gene_expression of VEGFA 3 274 0.58 201.8 31.1
65 INT6058 Localization of Fos 1 73 0.81 16.7 30.84
66 INT65960 Gene_expression of BCL2 1 352 0.78 312.03 30.73
67 INT7894 Negative_regulation of Vip 1 59 0.59 11.76 27.36
68 INT22764 Localization of Ptger2 1 81 0.64 24.38 26.77
69 INT90313 Negative_regulation of Gene_expression of Casp3 1 57 0.57 22.23 26.77
70 INT100861 Binding of CRP 1 179 0.48 175.2 26.45
71 INT17739 Gene_expression of S100B 1 226 0.78 132.7 26.4
72 INT69036 Gene_expression of IL18 6 99 0.77 77.92 25.95
73 INT50490 Regulation of PTGS2 1 80 0.48 39.51 25.85
74 INT288 Positive_regulation of Sct 1 88 0.70 32.83 24.5
75 INT29704 Regulation of Casp3 1 51 0.56 22.13 22.79
76 INT26719 Negative_regulation of Gene_expression of Th 1 38 0.58 11.87 22.78
77 INT66753 Negative_regulation of Positive_regulation of Tnf 1 45 0.59 35.28 22.33
78 INT2386 Gene_expression of Pgr 1 112 0.78 45.46 22.19
79 INT35711 Positive_regulation of Sdcbp 1 110 0.60 50.45 22.11
80 INT78057 Localization of Tlr4 1 140 0.77 67.75 21.72
81 INT5503 Negative_regulation of Gene_expression of Crh 1 38 0.59 16.82 21.34
82 INT52693 Positive_regulation of Gene_expression of Ptgs2 2 57 0.70 25.51 21.18
83 INT28216 Gene_expression of HRAS 3 173 0.75 93.97 20.78
84 INT440 Regulation of Gene_expression of Crh 2 44 0.62 17.71 20.73
85 INT12243 Positive_regulation of PRSS1 2 91 0.70 52.87 19.48
86 INT68970 Positive_regulation of Pnoc 1 33 0.67 9.29 19.08
87 INT87861 Gene_expression of Il18 1 33 0.78 30.44 18.42
88 INT5841 Gene_expression of Vim 1 181 0.72 138.54 16.33
89 INT10214 Gene_expression of VIM 1 153 0.78 115.88 16.29
90 INT36554 Gene_expression of PRSS1 2 70 0.78 50.25 15.33
91 INT10360 Positive_regulation of Ifng 1 33 0.68 21.73 15.19
92 INT53948 Regulation of Gene_expression of Cpox 1 40 0.51 20.97 13.87
93 INT78472 Gene_expression of CDKN2A 1 223 0.78 173.76 13.61
94 INT91817 Positive_regulation of RETNLB 1 22 0.34 21.4 13.12
95 INT59080 Negative_regulation of Gene_expression of PTGS2 1 55 0.58 22.92 12.39
96 INT4460 Regulation of Mpo 1 44 0.62 31.16 12.11
97 INT25963 Gene_expression of DES 1 122 0.75 98.81 11.25
98 INT49266 Positive_regulation of Arigg4 1 37 0.47 53.79 11.2
99 INT85535 Negative_regulation of Gene_expression of Ptgs2 1 27 0.51 16.04 10.01
100 INT61171 Gene_expression of S100A8 1 92 0.76 57.74 9.98
101 INT81664 Positive_regulation of Gene_expression of Pnoc 1 12 0.68 2.51 9.75
102 INT87863 Positive_regulation of IL18 2 40 0.69 34.08 9.53
103 INT64346 Positive_regulation of S100B 2 95 0.70 63.11 9.17
104 INT2139 Negative_regulation of Cea 1 55 0.43 43.59 9.14
105 INT49325 Gene_expression of Cd34 1 102 0.78 82.75 8.97
106 INT3755 Positive_regulation of GBE1 2 29 0.40 8.99 8.91
107 INT70848 Gene_expression of Casp1 7 24 0.77 10.97 8.52
108 INT4991 Positive_regulation of Vim 1 74 0.69 69.84 8.33
109 INT8424 Positive_regulation of Gene_expression of Vip 1 11 0.70 8.01 8.31
110 INT36798 Gene_expression of Mki67 2 178 0.77 132 8.24
111 INT25953 Positive_regulation of Localization of Ptger2 1 29 0.42 5.91 8.1
112 INT6511 Positive_regulation of AFP 2 76 0.70 70.15 7.28
113 INT35712 Regulation of Sdcbp 1 19 0.23 5.3 6.58
114 INT113420 Positive_regulation of Gene_expression of IL18 1 22 0.69 19.96 5.53
115 INT121801 Binding of Aip 1 18 0.36 24.1 5.26
116 INT70613 Negative_regulation of Gene_expression of BCL2 1 48 0.59 38.91 5.22
117 INT28084 Positive_regulation of VIM 1 49 0.67 35.12 5.15
118 INT15652 Positive_regulation of ENO2 1 37 0.68 33.39 5.02
119 INT70654 Gene_expression of Actg2 1 27 0.67 18.62 4.79
120 INT37652 Positive_regulation of Pgr 1 29 0.59 9.09 4.67
121 INT2836 Positive_regulation of PAEP 1 51 0.67 26.69 4.57
122 INT78659 Gene_expression of Thim 1 17 0.28 14.34 4.4
123 INT35122 Negative_regulation of Sdcbp 1 43 0.51 22.01 4.34
124 INT4711 Regulation of ELK3 1 17 0.62 2.36 4.26
125 INT745 Gene_expression of Afp 1 65 0.78 52.89 4.24
126 INT36335 Localization of Tgfb1 1 19 0.79 7.06 4.17
127 INT138872 Gene_expression of SPINK5 1 21 0.58 30.11 4.12
128 INT68269 Gene_expression of CD99 1 49 0.77 47.38 3.86
129 INT35175 Localization of IL18 2 18 0.80 12.96 3.83
130 INT124185 Negative_regulation of Kit 1 57 0.59 35.43 3.61
131 INT36142 Negative_regulation of Hmgcr 1 33 0.46 15.91 3.54
132 INT51607 Positive_regulation of DES 1 33 0.67 32.24 3.29
133 INT67379 Positive_regulation of Cd34 1 38 0.58 26.18 3.28
134 INT22092 Gene_expression of SERPINA3 2 17 0.75 11.57 3.16
135 INT22944 Regulation of Grhpr 1 12 0.26 0.78 3
136 INT78248 Negative_regulation of Cdkn2a 1 17 0.59 15.15 2.8
137 INT139562 Transcription of IL18 1 10 0.68 6.14 2.73
138 INT92141 Negative_regulation of CDKN2A 1 53 0.57 44.23 2.48
139 INT100394 Gene_expression of Trp53bp2 3 13 0.65 9.24 2.18
140 INT9908 Negative_regulation of IAPP 1 29 0.57 19.37 2.12
141 INT94128 Positive_regulation of Gene_expression of Il18 1 6 0.50 3.64 2.06
142 INT94772 Gene_expression of Cdkn2a 1 14 0.75 8.25 2.04
143 INT125226 Binding of Nf2 2 7 0.48 5.94 2.02
144 INT107178 Gene_expression of Smad4 3 12 0.65 9.85 1.92
145 INT56925 Negative_regulation of TSC1 1 54 0.52 63.39 1.87
146 INT8556 Positive_regulation of NQO1 3 12 0.70 5.11 1.78
147 INT94827 Gene_expression of HBS1L 1 24 0.67 26.11 1.61
148 INT230 Positive_regulation of GGTLC1 1 14 0.68 11.78 1.55
149 INT11948 Negative_regulation of Gene_expression of Vip 1 9 0.43 2.8 1.54
150 INT118430 Positive_regulation of Gene_expression of VIM 1 8 0.47 2.14 1.53
151 INT146142 Positive_regulation of Trem1 1 11 0.44 7.75 1.46
152 INT76477 Positive_regulation of CD99 1 14 0.50 14.77 1.42
153 INT56944 Positive_regulation of SERPINA3 2 8 0.67 6.56 1.32
154 INT100860 Positive_regulation of S100A9 1 5 0.39 5.79 1.2
155 INT112435 Positive_regulation of Gene_expression of Trp53bp2 1 2 0.37 3.48 1.08
156 INT138201 Transcription of PAEP 1 4 0.67 1.8 1.02
157 INT20201 Positive_regulation of Fgf12 1 8 0.43 15.13 0.98
158 INT146141 Localization of Trem1 3 5 0.49 2.5 0.9
159 INT129721 Positive_regulation of TNFRSF10D 1 3 0.51 2.75 0.9
160 INT115238 Positive_regulation of Gene_expression of Casp1 3 5 0.68 1.78 0.88
161 INT136531 Binding of Men1 1 8 0.47 9.62 0.65
162 INT649 Positive_regulation of Afp 1 10 0.55 6.5 0.62
163 INT134951 Gene_expression of NQO1 2 14 0.78 7.87 0.61
164 INT70760 Positive_regulation of Actg2 1 8 0.48 6.23 0.61
165 INT83909 Positive_regulation of Gene_expression of SERPINA3 2 4 0.67 3.04 0.56
166 INT29441 Negative_regulation of Gene_expression of Cea 1 6 0.20 5.97 0.55
167 INT103781 Negative_regulation of Smad4 4 9 0.42 4.42 0.54
168 INT103271 Regulation of Sit1 1 3 0.24 1.32 0.47
169 INT109703 Positive_regulation of Sit1 2 10 0.41 1.83 0.43
170 INT265 Negative_regulation of Por 1 4 0.59 0.34 0.41
171 INT80978 Positive_regulation of Gene_expression of DES 1 4 0.49 4.68 0.3
172 INT146792 Negative_regulation of Nf2 1 2 0.59 3.49 0.3
173 INT113421 Negative_regulation of Localization of IL18 1 2 0.58 0.87 0.27
174 INT134810 Binding of CELA1 1 1 0.12 1.02 0.22
175 INT87196 Regulation of Hmgcr 1 3 0.45 0.7 0.14
176 INT138898 Gene_expression of Cd99l2 1 2 0.09 2.15 0.12
177 INT135842 Binding of Csn 1 2 0.07 0.06 0.11
178 INT138899 Positive_regulation of Cd99l2 1 1 0.07 1.16 0.09
179 INT120453 Positive_regulation of Positive_regulation of GGTLC1 1 1 0.06 1.19 0.09
180 INT146140 Regulation of Localization of Trem1 1 1 0.27 0.25 0.07
181 INT126208 Binding of PTN 1 2 0.36 0 0
182 INT143571 Positive_regulation of lt 1 2 0.31 0.27 0
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