J:Yakugaku Zasshi

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT150191 CEACAM3 Positive_regulation of Gene_expression of FOS 1 1 0.34 0.14 1.16
2 INT166625 Acer3 Positive_regulation of Trpa1 1 2 0.01 1.91 1
3 INT167431 Binding of APP and MYO1C 1 2 0.23 1.38 0.83
4 INT166624 Acer3 Positive_regulation of Acer3 Positive_regulation of Trpa1 1 1 0.00 0.78 0.37

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT796 Gene_expression of Penk 1 1902 0.78 275.47 1057.59
2 INT1912 Gene_expression of Calca 1 1152 0.78 453.25 739.84
3 INT58061 Gene_expression of Trpv1 3 1117 0.78 451.54 637.59
4 INT443 Localization of POMC 1 1020 0.81 284.52 443.17
5 INT50058 Negative_regulation of Cpox 1 907 0.58 426.28 428.29
6 INT64202 Positive_regulation of Trpv1 2 643 0.70 249.66 397.42
7 INT9158 Gene_expression of Tnf 1 722 0.78 522.01 277.68
8 INT16868 Gene_expression of Il6 1 807 0.78 499.48 256.57
9 INT6665 Gene_expression of FOS 2 520 0.77 165.31 217.66
10 INT6481 Binding of TNF 1 624 0.48 510.2 214.82
11 INT2640 Gene_expression of Pomc 1 424 0.78 120.72 155.37
12 INT60126 Regulation of Trpv1 1 186 0.62 85.53 133.4
13 INT65054 Positive_regulation of Nfkb1 2 285 0.70 149.33 126.73
14 INT5008 Localization of Calca 3 204 0.81 80.35 125.16
15 INT6128 Positive_regulation of Localization of POMC 1 256 0.70 68.77 121.64
16 INT397 Localization of SST 1 232 0.81 58.05 101.19
17 INT74826 Gene_expression of Slc1a2 3 131 0.78 61.83 100.84
18 INT12763 Phosphorylation of Prkcg 1 167 0.82 38.91 89.63
19 INT1472 Positive_regulation of Ins1 3 349 0.69 146.2 86.36
20 INT5617 Localization of Nppa 2 266 0.81 83.51 83.89
21 INT3214 Localization of Ins1 1 527 0.80 196.9 79.26
22 INT3657 Gene_expression of Ins1 1 514 0.78 321.69 75.76
23 INT5969 Gene_expression of Il1a 1 221 0.75 96.31 71.38
24 INT97674 Positive_regulation of Localization of Calca 1 70 0.69 27.71 51.79
25 INT74827 Positive_regulation of Gene_expression of Slc1a2 1 52 0.70 26.54 50.63
26 INT2323 Gene_expression of Trh 1 146 0.78 29.92 49.5
27 INT109430 Positive_regulation of Trpa1 4 119 0.70 44 49.14
28 INT28265 Positive_regulation of Calca 1 62 0.70 29.1 41.17
29 INT80075 Regulation of Gene_expression of Trpv1 1 55 0.62 32.42 36.88
30 INT100733 Positive_regulation of F2RL1 1 62 0.70 59.14 35.22
31 INT12765 Positive_regulation of Phosphorylation of Prkcg 2 59 0.66 20.16 34.67
32 INT8746 Negative_regulation of Calca 1 50 0.59 21.22 33.45
33 INT65536 Negative_regulation of Positive_regulation of Nfkb1 2 77 0.59 38.86 33.33
34 INT8915 Gene_expression of Igf1 1 199 0.78 78.58 32.51
35 INT16814 Negative_regulation of COX5A 1 74 0.57 33.72 28.63
36 INT22499 Regulation of Calca 1 42 0.62 17.32 28.02
37 INT48979 Regulation of Gene_expression of FOS 1 52 0.61 14.4 25.95
38 INT1728 Negative_regulation of Cndp2 1 36 0.57 3.76 25.39
39 INT5622 Gene_expression of Nppa 4 101 0.78 49.46 25.31
40 INT47741 Negative_regulation of Flvcr2 1 43 0.51 5.72 23.37
41 INT18884 Regulation of RYBP 1 25 0.38 11.43 23.2
42 INT89056 Phosphorylation of Trpv1 1 46 0.82 13.52 22.16
43 INT693 Negative_regulation of Localization of SST 1 46 0.59 8.57 21.75
44 INT48144 Gene_expression of Fgf2 1 117 0.78 43 20.48
45 INT96532 Negative_regulation of Gene_expression of Slc1a2 1 24 0.59 14.22 17.91
46 INT3656 Positive_regulation of Gene_expression of Ins1 2 74 0.54 44.94 17.36
47 INT98110 Regulation of Gene_expression of Slc1a2 2 16 0.62 11.76 17.31
48 INT23657 Positive_regulation of APP 1 64 0.70 39.76 16.68
49 INT13400 Negative_regulation of Enpep 1 30 0.50 4.23 15.86
50 INT98109 Regulation of Slc1a3 1 15 0.52 6.87 14.43
51 INT78480 Localization of Nfkb1 1 39 0.80 23.14 13.64
52 INT29745 Binding of APP 1 47 0.48 26.49 12.4
53 INT120432 Regulation of Trpa1 1 22 0.61 9.65 12.36
54 INT60461 Positive_regulation of Gene_expression of Il1a 1 40 0.61 17.23 12.35
55 INT9083 Gene_expression of Nppb 3 74 0.78 70.96 12.19
56 INT62580 Gene_expression of Cyp2e1 1 31 0.78 15.4 11.08
57 INT74828 Regulation of Slc1a2 2 12 0.61 3.92 10.3
58 INT53746 Regulation of Cyp2e1 1 11 0.62 3.82 9.52
59 INT89053 Positive_regulation of Phosphorylation of Trpv1 2 16 0.70 8.89 9.39
60 INT103251 Negative_regulation of Localization of Calca 1 13 0.43 9.36 8.86
61 INT1049 Positive_regulation of hpc 1 18 0.40 3.16 8.45
62 INT5481 Binding of TYR 1 26 0.47 1.3 7.95
63 INT10924 Positive_regulation of Sysbp1 1 25 0.04 11.12 7.35
64 INT84932 Negative_regulation of APP 2 29 0.57 28.45 7.2
65 INT127037 Gene_expression of Ppig 1 26 0.65 16.08 6.84
66 INT2217 Positive_regulation of Positive_regulation of Ins1 1 21 0.69 7.66 6.32
67 INT64689 Positive_regulation of Gene_expression of Fgf2 1 30 0.70 12.05 6.2
68 INT16687 Regulation of Cndp2 1 6 0.44 0.23 6.11
69 INT111470 Positive_regulation of EPRS 1 18 0.44 11.42 5.29
70 INT52088 Binding of Cyp2e1 1 8 0.48 2.5 4.43
71 INT10175 Positive_regulation of Ns5atp9 1 16 0.69 6.13 4.2
72 INT71885 Protein_catabolism of Nfkb1 1 8 0.53 5.34 3.69
73 INT17685 Negative_regulation of Cog1 1 23 0.42 15.65 3.56
74 INT9085 Localization of Nppb 2 32 0.81 15.1 3.47
75 INT33661 Regulation of Tbpl1 1 7 0.44 5.36 3.26
76 INT9055 Positive_regulation of Cog1 1 22 0.68 14.08 2.95
77 INT9764 Gene_expression of Adrb3 1 10 0.62 4.14 2.33
78 INT151000 Negative_regulation of Atp12a 1 10 0.35 5.13 2.2
79 INT150192 Positive_regulation of CPA1 2 3 0.23 1.29 2.2
80 INT84388 Negative_regulation of PDE3B 2 16 0.57 11.25 2.18
81 INT35146 Negative_regulation of PLG 1 27 0.57 17.63 1.98
82 INT32795 Positive_regulation of Hypism 1 17 0.15 20.16 1.73
83 INT16229 Negative_regulation of Ccbp2 2 1 0.19 0 1.37
84 INT55899 Positive_regulation of Ptafr 1 6 0.63 4.7 1.34
85 INT91298 Negative_regulation of EPRS 1 4 0.40 0.79 1.31
86 INT93598 Positive_regulation of Gene_expression of Zic5 1 1 0.00 0.57 1.26
87 INT93599 Gene_expression of Zic5 1 1 0.00 0.57 1.25
88 INT150193 Negative_regulation of CPA1 1 1 0.21 0.13 1.24
89 INT150194 Regulation of Positive_regulation of CPA1 1 1 0.13 0.17 1.16
90 INT132623 Transcription of Cyp2e1 2 2 0.53 0.56 0.98
91 INT163995 Negative_regulation of Gene_expression of Ppig 1 4 0.24 2.07 0.89
92 INT163987 Negative_regulation of FMO3 1 2 0.59 1.43 0.66
93 INT163990 Gene_expression of FMO3 5 6 0.78 1.03 0.64
94 INT92426 Gene_expression of Ts1 1 10 0.58 6.14 0.59
95 INT163991 Positive_regulation of Regulation of Cyp2e1 1 1 0.70 0.28 0.52
96 INT163994 Positive_regulation of Binding of Cyp2e1 1 2 0.50 0.45 0.5
97 INT163993 Gene_expression of Hnf1a 1 2 0.65 1.38 0.49
98 INT145928 Negative_regulation of SERPINA4 1 5 0.07 2.05 0.43
99 INT163351 Negative_regulation of MIR527 1 1 0.00 0 0.43
100 INT113364 Regulation of NAA50 1 2 0.44 1.9 0.41
101 INT167432 Binding of MYO1C 1 1 0.19 0.67 0.41
102 INT163350 Negative_regulation of CDR2 1 1 0.00 0 0.39
103 INT84392 Localization of Hdc 1 2 0.70 0.98 0.34
104 INT127488 Negative_regulation of Pkn1 1 1 0.00 0.2 0.28
105 INT163984 Transcription of FMO3 2 1 0.72 0 0.15
106 INT163988 Regulation of Gene_expression of FMO3 2 1 0.45 0 0.15
107 INT163986 Regulation of Transcription of FMO3 2 1 0.45 0 0.15
108 INT84395 Protein_catabolism of Pla2g4a 1 1 0.02 0.41 0.12
109 INT115419 Positive_regulation of Gene_expression of Adrb3 1 1 0.37 0.77 0.11
110 INT163989 Regulation of Positive_regulation of FMO3 1 1 0.45 0 0.07
111 INT163985 Positive_regulation of FMO3 1 1 0.50 0 0.07
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