J:mBio

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT339495 Tlr4 Positive_regulation of Eif2ak2 1 5 0.21 0.58 0.77
2 INT339493 Binding of Irak1 and Irak3 1 1 0.02 0.17 0.41
3 INT339504 Binding of Irak1 and Tlr4 1 1 0.08 0.12 0.38
4 INT339511 Binding of Tlr4 and Traf6 1 1 0.05 0.12 0.38
5 INT339512 Negative_regulation of Binding of Tlr4 and Traf6 1 1 0.05 0.17 0.38
6 INT339506 Binding of Irak1 and Traf6 1 1 0.03 0.12 0.37
7 INT339494 Eif2ak2 Positive_regulation of Tlr4 1 1 0.13 0.18 0.28
8 INT339509 Tlr4 Regulation of Eif2ak2 1 1 0.08 0.16 0.23
9 INT339516 Binding of Eif2ak2 and TIRAP 1 1 0.25 0.19 0.23
10 INT339501 Binding of Eif2ak2 and Tlr4 1 1 0.14 0.19 0.23
11 INT339503 Tlr2 Positive_regulation of Eif2ak2 1 1 0.12 0.09 0.19
12 INT339505 Tlr3 Positive_regulation of Eif2ak2 1 1 0.14 0.09 0.19
13 INT339510 Tlr4 Positive_regulation of Socs1 1 1 0.06 0.1 0.18
14 INT339513 Binding of Socs1 and Eif2ak2 1 2 0.04 0.07 0.15
15 INT339498 Binding of Il1rap and Positive_regulation of Irak1 1 1 0.01 0 0.1
16 INT339500 Negative_regulation of Socs1 Positive_regulation of Eif2ak2 1 2 0.05 0.31 0.09
17 INT339507 Tlr4 Positive_regulation of Phosphorylation of Gopc 1 1 0.03 0 0.04
18 INT339499 Socs1 Regulation of Gene_expression of Eif2ak2 1 1 0.05 0.09 0
19 INT324413 Binding of MIOX and Miox 1 2 0.01 0 0
20 INT339514 Socs1 Regulation of Eif2ak2 1 2 0.07 0.09 0
21 INT339492 Tlr4 Regulation of Gene_expression of Eif2ak2 1 1 0.12 0.09 0
22 INT339497 Tlr4 Positive_regulation of Gene_expression of Eif2ak2 1 1 0.13 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT9659 Gene_expression of Il6 2 991 0.78 715.11 265.57
2 INT95787 Positive_regulation of Mapk1 1 568 0.70 226.51 220.94
3 INT49441 Negative_regulation of Cpox 1 494 0.59 303.22 177.46
4 INT120811 Gene_expression of Gopc 9 1174 0.59 428.49 150.55
5 INT65600 Positive_regulation of Casp3 3 376 0.70 198.44 128.03
6 INT7533 Gene_expression of Tlr4 6 720 0.78 343.22 121.57
7 INT940 Negative_regulation of Ptgs1 1 219 0.59 104.34 95.97
8 INT92434 Phosphorylation of Mapk1 1 287 0.82 91.65 83.46
9 INT6486 Positive_regulation of Tnf 1 168 0.70 123.47 66.05
10 INT9657 Positive_regulation of Gene_expression of Il6 2 237 0.70 180.45 63.6
11 INT1951 Positive_regulation of Tlr4 6 345 0.70 176.99 62.42
12 INT11318 Gene_expression of Gtf3a 3 274 0.52 183.82 60.89
13 INT169926 Positive_regulation of Gopc 4 416 0.46 157.8 58.67
14 INT31116 Gene_expression of Casp3 5 192 0.78 78.21 57.43
15 INT110023 Negative_regulation of Mapk14 1 127 0.59 84.27 45.42
16 INT157666 Positive_regulation of GOPC 1 335 0.60 120.19 42.75
17 INT92437 Positive_regulation of Phosphorylation of Mapk1 1 113 0.70 32.19 40.29
18 INT102611 Negative_regulation of Positive_regulation of Mapk1 1 74 0.58 35.57 39.37
19 INT81289 Positive_regulation of Gene_expression of Tlr4 1 192 0.69 104.5 33.89
20 INT67039 Positive_regulation of Cpox 1 144 0.65 98.4 33.77
21 INT56809 Binding of Tlr4 1 184 0.48 106.02 31.18
22 INT110020 Gene_expression of Mapk14 2 142 0.77 72.33 30.08
23 INT85395 Gene_expression of Scn11a 3 62 0.78 17.97 26.89
24 INT16428 Positive_regulation of Gtf3a 1 135 0.20 106.44 26.67
25 INT172458 Regulation of Gopc 2 155 0.53 62.57 24.86
26 INT134651 Binding of TLR4 1 89 0.48 66.96 23.19
27 INT142594 Gene_expression of Tlr2 3 165 0.78 139.73 22.26
28 INT7535 Negative_regulation of Tlr4 2 111 0.56 56.84 21.37
29 INT78694 Positive_regulation of Gene_expression of Casp3 1 46 0.66 18.64 19.62
30 INT170051 Positive_regulation of Gene_expression of Gopc 2 150 0.43 56.75 16.93
31 INT43906 Regulation of Tlr4 2 71 0.53 35.18 15.49
32 INT67641 Negative_regulation of Gene_expression of Tlr4 1 90 0.58 46 14.6
33 INT53080 Positive_regulation of Ptgs1 1 42 0.42 23.58 14.37
34 INT178306 Negative_regulation of Gene_expression of Gopc 2 71 0.37 26.43 9.74
35 INT52442 Binding of Ptgs1 1 16 0.35 9.05 8.78
36 INT50290 Binding of Cpox 1 29 0.27 17.19 8.01
37 INT101189 Transcription of Gtf3a 1 49 0.17 24.39 7.93
38 INT175526 Phosphorylation of Gopc 2 73 0.53 21.08 7.86
39 INT53871 Gene_expression of Socs1 10 32 0.71 22.83 6.21
40 INT183681 Positive_regulation of Tlr3 3 20 0.62 16.25 4.54
41 INT110024 Negative_regulation of Gene_expression of Mapk14 1 19 0.42 7.83 4.21
42 INT158596 Binding of Tlr3 1 24 0.47 11.66 3.69
43 INT1683 Gene_expression of Cux1 6 20 0.58 6.29 3.59
44 INT271575 Gene_expression of MIOX 3 25 0.06 11.26 3.31
45 INT178711 Protein_catabolism of Tlr4 1 15 0.84 6.75 3.19
46 INT59342 Negative_regulation of NPC1 1 20 0.44 20.21 2.79
47 INT70197 Negative_regulation of Positive_regulation of Ptgs1 1 6 0.24 2.61 2.44
48 INT203839 Positive_regulation of Eif2ak2 14 18 0.32 4.36 2.22
49 INT184054 Negative_regulation of Gene_expression of Socs1 1 7 0.53 9.18 2.22
50 INT145196 Gene_expression of Irak3 1 5 0.23 4.23 2.13
51 INT145195 Positive_regulation of Irak3 2 4 0.15 3.65 2.12
52 INT184042 Negative_regulation of Socs1 2 9 0.46 8.1 1.88
53 INT208890 Gene_expression of Irak1 1 7 0.65 2.42 1.87
54 INT102751 Positive_regulation of polymerase 5 7 0.10 3.06 1.81
55 INT166819 Gene_expression of IMPA1 2 12 0.65 3.85 1.77
56 INT191862 Phosphorylation of Tlr4 1 17 0.79 6.89 1.74
57 INT184068 Positive_regulation of Socs1 3 7 0.51 4.03 1.73
58 INT78005 Negative_regulation of Binding of Cpox 1 7 0.31 3.19 1.7
59 INT254250 Regulation of Socs1 1 5 0.06 3.04 1.66
60 INT70715 Regulation of Il4i1 1 3 0.07 0.56 1.63
61 INT89209 Negative_regulation of Binding of Ptgs1 1 6 0.06 2.7 1.39
62 INT233970 Regulation of Myd88 1 7 0.45 5.2 1.28
63 INT298979 Gene_expression of Traf6 1 5 0.31 1.75 1.21
64 INT254188 Positive_regulation of Irak1 1 7 0.44 3.46 0.87
65 INT157506 Gene_expression of Ly96 2 10 0.30 1.69 0.86
66 INT339476 Regulation of Eif2ak2 7 1 0.28 0.57 0.86
67 INT184014 Binding of Socs1 6 2 0.34 0.97 0.84
68 INT326427 Gene_expression of Eif2ak2 17 2 0.36 1.32 0.83
69 INT328226 Negative_regulation of Positive_regulation of Cpox 1 3 0.11 1.49 0.73
70 INT284453 Positive_regulation of Positive_regulation of Eif2ak2 2 2 0.32 1.23 0.71
71 INT154805 Gene_expression of Polymerase 1 13 0.16 4.4 0.65
72 INT184030 Gene_expression of Socs2 2 8 0.74 3.54 0.63
73 INT184017 Positive_regulation of Gene_expression of Socs1 2 7 0.63 2.47 0.62
74 INT334230 Negative_regulation of Irak1 1 2 0.38 0.3 0.51
75 INT339468 Negative_regulation of Eif2ak2 7 1 0.20 0.21 0.51
76 INT200435 Binding of polymerase 1 6 0.16 5.56 0.47
77 INT152229 Positive_regulation of Regulation of Tlr4 1 2 0.40 0.29 0.46
78 INT326428 Positive_regulation of Gene_expression of Eif2ak2 5 2 0.32 0.75 0.43
79 INT339469 Negative_regulation of Positive_regulation of Eif2ak2 1 1 0.20 0.4 0.42
80 INT271571 Positive_regulation of MIOX 2 4 0.09 3.65 0.41
81 INT339484 Phosphorylation of Eif2ak2 7 1 0.38 0.46 0.41
82 INT339480 Negative_regulation of Positive_regulation of Irak3 1 1 0.05 0.12 0.41
83 INT324756 Regulation of Irak1 1 5 0.40 0.87 0.35
84 INT293942 Negative_regulation of Gene_expression of Cux1 2 3 0.34 0.97 0.31
85 INT293946 Positive_regulation of Gene_expression of Cux1 1 2 0.40 0.65 0.31
86 INT203828 Binding of Eif2ak2 2 1 0.22 0.71 0.24
87 INT232067 Gene_expression of RNPC3 2 6 0.65 0.95 0.2
88 INT254194 Regulation of Positive_regulation of Tlr3 1 2 0.52 0.79 0.19
89 INT310483 Positive_regulation of Eomes 1 2 0.38 0.85 0.19
90 INT185254 Gene_expression of Pax6 5 14 0.72 1.77 0.16
91 INT336418 Negative_regulation of Binding of Tlr3 1 1 0.36 0.59 0.16
92 INT5433 Regulation of polymerase 1 8 0.03 4.2 0.15
93 INT339467 Protein_catabolism of Eif2ak2 3 1 0.46 0.08 0.14
94 INT339479 Regulation of Negative_regulation of Eif2ak2 1 1 0.13 0.08 0.14
95 INT339473 Negative_regulation of Gene_expression of Eif2ak2 2 1 0.27 0.13 0.13
96 INT261158 Positive_regulation of Gene_expression of Socs2 1 2 0.08 0.13 0.1
97 INT339482 Binding of Il1rap 1 1 0.01 0 0.1
98 INT271580 Binding of MIOX 2 2 0.04 0.68 0.07
99 INT232069 Positive_regulation of RNPC3 2 3 0.13 0.6 0.05
100 INT319100 Positive_regulation of Gene_expression of RNPC3 1 2 0.05 0.39 0.05
101 INT339485 Positive_regulation of Negative_regulation of Socs1 1 1 0.11 0.1 0.05
102 INT346939 Positive_regulation of Gene_expression of polymerase 1 1 0.04 0.32 0.05
103 INT339474 Positive_regulation of Protein_catabolism of Eif2ak2 1 1 0.22 0 0.05
104 INT339475 Phosphorylation of Socs1 1 1 0.17 0.16 0.04
105 INT324394 Positive_regulation of Miox 1 2 0.06 0.36 0.03
106 INT170377 Gene_expression of Eomes 4 2 0.42 0.37 0.03
107 INT206481 Transcription of Pax6 1 2 0.41 0.19 0.03
108 INT336419 Negative_regulation of Gene_expression of Pax6 1 1 0.45 0.12 0.03
109 INT336415 Positive_regulation of Gene_expression of Eomes 1 1 0.38 0.17 0.03
110 INT336414 Transcription of Cux1 1 1 0.47 0.23 0.03
111 INT339489 Binding of TIRAP 1 1 0.36 0.05 0.03
112 INT204472 Binding of RNPC3 1 6 0.06 1.65 0
113 INT291889 Negative_regulation of Pax6 1 2 0.45 0.39 0
114 INT263915 Binding of SLN 1 2 0.12 0.81 0
115 INT324411 Localization of MIOX 1 1 0.07 0 0
116 INT336412 Negative_regulation of Gene_expression of Eomes 1 1 0.23 0.11 0
117 INT324410 Regulation of Binding of MIOX 1 1 0.05 0.17 0
118 INT346938 'Positive_regulation of Binding of ' 1 1 0.04 0.19 0
119 INT324449 Regulation of RNPC3 1 1 0.07 0.08 0
120 INT324395 Gene_expression of Ir2 1 1 0.65 0.19 0
121 INT336416 Binding of Pax6 1 1 0.28 0 0
122 INT324393 Binding of Miox 1 1 0.04 0 0
123 INT324412 Negative_regulation of Localization of MIOX 1 1 0.04 0 0
124 INT336420 Positive_regulation of Binding of Pax6 1 1 0.38 0 0
125 INT324396 Negative_regulation of Miox 1 1 0.05 0 0
126 INT336411 Gene_expression of Olfr140 1 1 0.00 0.15 0
127 INT336413 Negative_regulation of Eomes 1 1 0.32 0.11 0
128 INT346940 Regulation of Binding of RNPC3 1 1 0.05 0.19 0
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