P:5HT

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pChart

Pain Term
Category Molecule
Synonyms 5-hydroxytriptamine
Pain Specific No
Documents 533
Hot Single Events 200
Hot Interactions 26

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for 5HT. They are ordered first by their pain relevance and then by number of times they were reported for 5HT. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT14687 Binding of Penk and Ppt1 1 0.41 0 2.46 100.00
2 INT36512 Binding of Htr2a and Man2a2 1 0.19 0 0.62 100.00
3 INT36511 Binding of Htr2a and Eef1a1 1 0.22 0 0.62 100.00
4 INT14199 GNRH1 Positive_regulation of Localization of Gh1 2 0.05 0 1.12 100.00
5 INT14200 GNRH1 Positive_regulation of Localization of Azi1 1 0.00 0 0.49 100.00
6 INT23576 Binding of Penk and Crh 2 0.18 0 0.62 100.00
7 INT235709 Binding of NA and SSR1 1 0.07 0.72 1.08 99.96
8 INT14197 Pde2a Positive_regulation of Localization of Gh1 2 0.04 0 1.08 99.52
9 INT14196 Glra2 Positive_regulation of Localization of Gh1 1 0.06 0 0.71 99.46
10 INT20530 Nts Regulation of Prss12 5 0.24 0.74 1.23 99.08
11 INT44502 Regulation of Mt1a Positive_regulation of Prl 1 0.14 0 0.74 97.80
12 INT44505 Mt1a Positive_regulation of Mt1a Positive_regulation of Prl 1 0.19 0 1.48 97.12
13 INT44504 Mt1a Positive_regulation of Prl 1 0.37 0 1.48 97.12
14 INT44503 Cubn Positive_regulation of Prl 1 0.18 0 0.74 96.60
15 INT102937 Gnrh1 Positive_regulation of Gene_expression of Lep 1 0.50 0 0.22 92.64
16 INT70254 Binding of Htr1a and Ca2 1 0.31 0.5 0.6 91.88
17 INT91391 Crh Regulation of Localization of Gnrh1 2 0.36 1.78 0.61 91.28
18 INT235404 Positive_regulation of RTCA Positive_regulation of Positive_regulation of Prkaca 1 0.00 0.22 0.45 91.16
19 INT235390 HTR1A Regulation of BGLAP 1 0.03 0.23 0.51 87.96
20 INT210862 Binding of POMC and Mc4r 1 0.34 0.42 0.17 87.32
21 INT159438 seb Positive_regulation of Gene_expression of Il1a 1 0.02 0 0.41 87.32
22 INT159439 sea Positive_regulation of Gene_expression of Il1a 1 0.07 0 0.41 87.32
23 INT64036 Binding of AVP and HTR1A 1 0.40 0.36 0.57 86.96
24 INT235389 Binding of BGLAP and HTR1A 1 0.03 0.15 0.45 86.08
25 INT235984 HTR1A Negative_regulation of MAPK1 1 0.01 0 0.16 81.40
26 INT236006 HTR1A Regulation of Grin2b 1 0.00 0 0.33 80.52
27 INT100084 Binding of CRH and CRHR2 1 0.32 1.11 0.19 79.52
28 INT353208 NEUROG2 Positive_regulation of Gene_expression of HTR1A 1 0.05 0.35 0.31 79.04
29 INT334351 Bdnf Regulation of Positive_regulation of Ephb1 1 0.18 1.27 1.2 76.96
30 INT151698 Binding of RNF130 and Vwf 1 0.04 0.29 0.37 76.48
31 INT236005 Positive_regulation of MAPK1 Positive_regulation of Binding of Map2 1 0.04 0 0.25 75.40
32 INT236004 Positive_regulation of MAPK1 Positive_regulation of Phosphorylation of Map2 1 0.04 0 0.24 75.40
33 INT151694 Binding of FBL and RNF130 1 0.40 0.23 0.36 74.48
34 INT91393 Crh Positive_regulation of SST 1 0.01 0.73 0.58 72.80
35 INT128044 Bdnf Positive_regulation of Ephb1 2 0.31 1.89 2.57 72.32
36 INT191480 Htr3a Positive_regulation of Ca2 1 0.02 0.12 0.23 71.76
37 INT120723 Positive_regulation of Trpv1 Positive_regulation of Localization of Calca 3 0.51 0.48 1.92 70.16
38 INT343597 Gys1 Regulation of Transcription of Gria2 1 0.00 0 0.55 69.44
39 INT37153 Binding of Mpz and Ptpn2 1 0.12 0.68 1.08 68.32
40 INT189303 Atp6v1e1 Positive_regulation of Gene_expression of TPH1 1 0.01 0.16 0.73 67.48
41 INT62059 Positive_regulation of SCN5A Positive_regulation of Gene_expression of FOS 1 0.01 0.42 0.66 64.16
42 INT25112 RYBP Negative_regulation of Binding of PLEKHM1 1 0.01 0 1.17 63.40
43 INT25109 Negative_regulation of COL7A1 Positive_regulation of PLEKHM1 1 0.01 0 1.16 62.88
44 INT25114 COL7A1 Positive_regulation of PLEKHM1 1 0.01 0 1.15 62.32
45 INT25113 RYBP Negative_regulation of Binding of PTGER2 1 0.05 0 1.02 53.00
46 INT25111 Binding of PTGDS and PLEKHM1 1 0.01 0 0.97 51.76
47 INT25110 RYBP Negative_regulation of MTHFS 1 0.02 0 0.92 48.56
48 INT203532 Negative_regulation of Pou4f1 Negative_regulation of Gene_expression of Pou4f2 1 0.34 0.44 0.19 46.88
49 INT235125 PDE2A Negative_regulation of Twist1 1 0.00 0.99 0.24 40.48
50 INT203528 Binding of Pou4f1 and H3 1 0.17 0.42 0.18 34.72
51 INT340212 Csf2 Positive_regulation of Pttg1ip 1 0.02 0.46 0.49 29.92
52 INT351276 CYP2D6 Regulation of CYP1A2 1 0.12 0 0.63 22.72
53 INT190981 Binding of Npy and Scn2a1 1 0.10 0 1.75 20.08
54 INT190987 Abat Regulation of Scn2a1 1 0.03 0.07 0.59 18.96
55 INT253895 Binding of Htr1b and Htr1d 1 0.40 0.52 1.74 5.00
56 INT189299 Atp6v1e1 Positive_regulation of Htr2a 1 0.01 1.01 1.41 5.00
57 INT281479 Drd2 Positive_regulation of Penk 1 0.23 0.4 1.3 5.00
58 INT210982 Binding of Cnr1 and Cfp 2 0.22 1.27 1.2 5.00
59 INT285659 Binding of Faah and Mgll 1 0.15 0.99 1.11 5.00
60 INT232426 HRH2 Regulation of Localization of PRL 1 0.15 0.38 0.94 5.00
61 INT281482 Drd2 Positive_regulation of Drd2 Positive_regulation of Penk 1 0.21 0.27 0.87 5.00
62 INT285660 Cnrip1 Negative_regulation of Kcnk3 1 0.00 0.23 0.85 5.00
63 INT285656 Cnrip1 Negative_regulation of Kcnk3 1 0.00 0.23 0.85 5.00
64 INT334358 Rvm Positive_regulation of Ephb1 1 0.17 0.98 0.82 5.00
65 INT334359 Negative_regulation of Rvm Positive_regulation of Ephb1 1 0.16 0.99 0.82 5.00
66 INT235087 NOS1 Positive_regulation of Localization of ABAT 1 0.02 0.61 0.81 5.00
67 INT228255 Binding of Akt1 and Pten 2 0.43 1.78 0.8 5.00
68 INT343599 Gys1 Regulation of Tst 1 0.01 0 0.75 5.00
69 INT190986 Per1 Positive_regulation of Scn2a1 1 0.17 0 0.74 5.00
70 INT190979 Per2 Positive_regulation of Scn2a1 1 0.20 0 0.74 5.00
71 INT123229 OXTR Regulation of Localization of PRL 2 0.30 0 0.73 5.00
72 INT190984 Binding of Scn2a1 and Gria1 1 0.03 0.08 0.71 5.00
73 INT235082 CA2 Positive_regulation of NOS1 2 0.11 0.62 0.63 5.00
74 INT311470 Binding of Crp and Il1 1 0.00 2.44 0.63 5.00
75 INT311466 Binding of Acsl1 and Il1 1 0.00 2.46 0.63 5.00
76 INT236003 Binding of HTR1A and Grin1 1 0.01 0.7 0.63 5.00
77 INT89902 SST Positive_regulation of Localization of PRL 2 0.40 0 0.61 5.00
78 INT311467 Binding of Crp and Acsl1 1 0.00 2.31 0.61 5.00
79 INT190988 Vip Positive_regulation of Gene_expression of Scn2a1 1 0.16 0.1 0.57 5.00
80 INT210830 OPRM1 Negative_regulation of ADCY1 1 0.00 0.06 0.55 5.00
81 INT255463 Binding of Avp and Avpr1a 1 0.06 0.67 0.54 5.00
82 INT232424 VIP Positive_regulation of Localization of PRL 1 0.36 0 0.53 5.00
83 INT253897 Binding of Htr1d and Pag1 1 0.30 0.29 0.52 5.00
84 INT253896 Binding of Htr1a and Pag1 1 0.30 0.29 0.49 5.00
85 INT235090 Positive_regulation of GRIN1 Positive_regulation of NOS1 1 0.42 0.81 0.49 5.00
86 INT285661 Binding of Mgll and FAAH2 1 0.05 0.23 0.45 5.00
87 INT218783 Binding of Faah and Cfp 1 0.04 0.55 0.45 5.00
88 INT232427 ABAT Regulation of PRL 1 0.08 0.26 0.45 5.00
89 INT190977 Npy Regulation of Scn2a1 1 0.16 0 0.4 5.00
90 INT302871 Negative_regulation of Adora2a Positive_regulation of Phosphorylation of Th 1 0.26 0.12 0.4 5.00
91 INT189300 Atp6v1e1 Regulation of Gene_expression of Prl 1 0.03 0.29 0.39 5.00
92 INT235083 CA2 Positive_regulation of Gene_expression of CALM1 1 0.01 0.63 0.37 5.00
93 INT232422 VIP Regulation of Gene_expression of PRL 1 0.40 0 0.37 5.00
94 INT235091 CALM1 Positive_regulation of NOS1 1 0.02 0.63 0.37 5.00
95 INT232421 Binding of PRL and Positive_regulation of Regulation of ABAT 1 0.09 0 0.37 5.00
96 INT232419 ABAT Positive_regulation of Localization of PRL 1 0.09 0 0.33 5.00
97 INT232425 Binding of ABAT and Positive_regulation of PRL 1 0.09 0.15 0.33 5.00
98 INT232420 PRL Positive_regulation of Regulation of ABAT 1 0.09 0 0.33 5.00
99 INT298472 LPA Positive_regulation of Gene_expression of CXCL16 1 0.05 0.41 0.32 5.00
100 INT203529 Pou4f1 Regulation of target gene 1 0.01 0.53 0.3 5.00
101 INT203526 Regulation of Pou4f1 Regulation of target gene 1 0.01 0.54 0.3 5.00
102 INT298501 Paf Regulation of Negative_regulation of Alms1 1 0.00 0.63 0.29 5.00
103 INT210828 POMC Positive_regulation of ADCY1 1 0.03 0.34 0.28 5.00
104 INT190983 Vip Positive_regulation of Gene_expression of Per1 1 0.13 0.51 0.27 5.00
105 INT190978 Vip Positive_regulation of Gene_expression of Per2 1 0.22 0.51 0.27 5.00
106 INT190998 ADCYAP1 Positive_regulation of Scn2a1 1 0.07 0.45 0.27 5.00
107 INT190996 ADCYAP1 Positive_regulation of Per1 1 0.06 0.45 0.27 5.00
108 INT190997 ADCYAP1 Positive_regulation of Per2 1 0.07 0.45 0.27 5.00
109 INT235088 NOS1 Regulation of ISYNA1 1 0.07 0.75 0.23 5.00
110 INT207783 Binding of MRC1 and Ap3d1 1 0.00 2.54 0.22 5.00
111 INT203527 Pou4f1 Negative_regulation of Neurod1 1 0.32 0.54 0.2 5.00
112 INT235084 IL6 Positive_regulation of Gene_expression of ISYNA1 1 0.02 1.11 0.2 5.00
113 INT203531 Pou4f1 Negative_regulation of Neurod4 1 0.46 0.54 0.2 5.00
114 INT281477 Binding of Pten and Th 1 0.28 0.4 0.19 5.00
115 INT322237 Binding of Agtrap and Hcm 1 0.14 2.3 0.19 5.00
116 INT262359 Binding of DISC1 and NDEL1 1 0.04 0.56 0.18 5.00
117 INT190985 Vip Regulation of Scn2a1 1 0.09 0 0.18 5.00
118 INT262361 Binding of Pde4b and DISC1 1 0.08 0.57 0.18 5.00
119 INT207784 Ap3d1 Regulation of CACNA1S 1 0.05 0.97 0.16 5.00
120 INT235085 NOS1 Positive_regulation of CA2 1 0.07 0.18 0.15 5.00
121 INT298475 LPA Positive_regulation of Gene_expression of IL8 1 0.07 0.38 0.15 5.00
122 INT298500 Alb Positive_regulation of Paf 1 0.01 0.34 0.15 5.00
123 INT207785 Binding of RYR1 and Ap3d1 1 0.06 3.24 0.13 5.00
124 INT207776 Binding of FKBP1A and RYR1 1 0.05 0.59 0.12 5.00
125 INT298476 CD40LG Positive_regulation of HLA-DRB1 1 0.01 0.33 0.12 5.00
126 INT298471 CD40LG Positive_regulation of CD80 1 0.04 0.33 0.12 5.00
127 INT210861 Abca4 Positive_regulation of AGRP 1 0.00 0 0.12 5.00
128 INT298479 CD40LG Positive_regulation of CD40LG Positive_regulation of HLA-DRB1 1 0.00 0.33 0.12 5.00
129 INT298474 IL4 Positive_regulation of HLA-DRB1 1 0.02 0.33 0.12 5.00
130 INT298478 IL4 Positive_regulation of CD40LG Positive_regulation of HLA-DRB1 1 0.01 0.33 0.12 5.00
131 INT298473 IL4 Positive_regulation of CD80 1 0.06 0.33 0.12 5.00
132 INT189301 Atp6v1e1 Positive_regulation of Positive_regulation of Htr2a 1 0.01 1.13 0.11 5.00
133 INT189298 Atp6v1e1 Positive_regulation of Positive_regulation of Htr1a 1 0.00 1.15 0.11 5.00
134 INT190982 Avp Positive_regulation of Scn2a1 1 0.17 0.17 0.1 5.00
135 INT298497 CTSC Positive_regulation of F10 Positive_regulation of F2 1 0.00 0.12 0.1 5.00
136 INT298502 F10 Positive_regulation of F2 1 0.00 0.12 0.09 5.00
137 INT322258 Binding of Agtrap and l5H1 1 0.40 0.62 0.09 5.00
138 INT210827 Binding of EPB41 and TPM3 1 0.03 0.17 0.06 5.00
139 INT190976 Binding of Scn2a1 and Gal 1 0.06 0 0.05 5.00
140 INT322236 Agt Regulation of Gene_expression of Slc6a4 1 0.42 0.63 0 5.00
141 INT322251 Slc6a4 Regulation of Gene_expression of Agtrap 1 0.43 0.63 0 5.00
142 INT322245 Binding of Hcm and Myh7 1 0.11 1.28 0 5.00
143 INT210829 Binding of POMC and GOPC 1 0.06 0.15 0 5.00
144 INT322250 Ace Regulation of Gene_expression of Agt 1 0.43 0.63 0 5.00
145 INT322246 Binding of Hcm and Tnni3 1 0.11 0.86 0 5.00
146 INT217308 Binding of Vcan and Timd4 1 0.01 0.79 0 5.00
147 INT322244 Binding of Hcm and Mybpc3 1 0.11 0.85 0 5.00
148 INT322248 Slc6a4 Regulation of Gene_expression of Agt 1 0.42 0.63 0 5.00
149 INT322243 Agt Regulation of Gene_expression of Agtrap 1 0.50 0.63 0 5.00
150 INT322259 Binding of Hcm and Tpm1 1 0.10 0.85 0 5.00
151 INT322240 Ace Regulation of Gene_expression of Htr2a 1 0.13 0.63 0 5.00
152 INT322239 Ace Regulation of Gene_expression of Agtrap 1 0.44 0.63 0 5.00
153 INT249996 Binding of ICAM1 and GPHA2 1 0.02 2.25 0 5.00
154 INT322249 Binding of Hcm and Tnnt2 1 0.11 0.86 0 5.00
155 INT249995 Positive_regulation of Binding of ICAM1 and GPHA2 1 0.02 2.43 0 5.00
156 INT262370 Binding of GAD1 and GNPTAB 1 0.00 1.36 0 5.00
157 INT247030 Prkaca Regulation of Positive_regulation of Cftr 1 0.05 0 0 5.00
158 INT322254 Agt Regulation of Gene_expression of Htr2a 1 0.15 0.63 0 5.00
159 INT322255 Mir155 Regulation of Agtrap 1 0.21 0.33 0 5.00
160 INT190980 Binding of Avp and Scn2a1 1 0.12 0 0 5.00
161 INT322253 Agt Regulation of Gene_expression of Ace 1 0.43 0.63 0 5.00
162 INT322238 Slc6a4 Regulation of Gene_expression of Ace 1 0.37 0.63 0 5.00
163 INT247031 Npr1 Positive_regulation of Prkaca 1 0.00 0 0 5.00
164 INT322256 Ace Regulation of Gene_expression of Slc6a4 1 0.37 0.63 0 5.00
165 INT322247 Slc6a4 Regulation of Gene_expression of Htr2a 1 0.13 0.63 0 5.00
166 INT322257 Binding of Mybpc3 and Myh7 1 0.34 0.43 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for 5HT. They are ordered first by their pain relevance and then by number of times they were reported in 5HT. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT15089 Regulation of SLC6A4 48 0.62 17.87 25.6 100.00
2 INT8362 Localization of Prss12 53 0.78 5.09 27 100.00
3 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 100.00
4 INT48923 Gene_expression of Ephb1 211 0.77 106.23 109.9 100.00
5 INT1396 Binding of Penk 355 0.48 22.79 269.65 100.00
6 INT112174 Gene_expression of Trpv4 47 0.78 26.26 20.09 100.00
7 INT17825 Gene_expression of Flvcr2 44 0.68 12.58 28.08 100.00
8 INT12135 Gene_expression of PLEK 62 0.75 34.13 12.47 100.00
9 INT796 Gene_expression of Penk 1902 0.78 275.47 1057.59 100.00
10 INT5324 Binding of Htr2a 23 0.47 7.14 14.66 100.00
11 INT9231 Binding of Htr3a 27 0.47 7.29 13.04 100.00
12 INT186893 Binding of BGLAP 10 0.37 6.19 2.02 100.00
13 INT64505 Localization of Htr2c 3 0.78 0.87 2.24 100.00
14 INT288625 Localization of MT2A 1 0.46 0.46 0.95 100.00
15 INT101340 Localization of MTNR1A 3 0.55 2.07 1.04 100.00
16 INT27412 Regulation of Nanog 7 0.58 0.81 2.59 100.00
17 INT115296 Gene_expression of TPH1 18 0.77 7.46 10.18 100.00
18 INT11077 Positive_regulation of Htr3a 63 0.67 15.61 22.7 100.00
19 INT288626 Localization of HTR2B 1 0.05 0.4 0.9 100.00
20 INT4740 Gene_expression of Th 298 0.78 61.27 154.03 100.00
21 INT67369 Gene_expression of Tph1 10 0.78 1.27 7.08 100.00
22 INT152756 Negative_regulation of Gene_expression of Tph1 1 0.25 0 1.15 100.00
23 INT137301 Negative_regulation of Gene_expression of TPH1 5 0.12 1.49 2.98 100.00
24 INT3034 Localization of Ngf 126 0.81 50.81 72.84 100.00
25 INT17824 Positive_regulation of Gene_expression of Flvcr2 15 0.41 6.66 10.23 100.00
26 INT75997 Positive_regulation of Localization of Ngf 14 0.69 7.78 9.41 100.00
27 INT78487 Localization of SSR1 2 0.73 0.95 1.7 100.00
28 INT47744 Binding of Slc6a4 21 0.48 5.52 9.45 100.00
29 INT52402 Negative_regulation of Htr2c 7 0.42 1.46 4.21 100.00
30 INT31810 Binding of HTR2B 6 0.47 2.75 4.36 100.00
31 INT62415 Binding of Htr7 6 0.47 1.76 2.26 100.00
32 INT12471 Regulation of Insrr 52 0.35 17.8 48.31 100.00
33 INT918 Positive_regulation of Localization of PRL 90 0.70 23.97 40.3 100.00
34 INT11429 Gene_expression of ADCY1 26 0.74 5.89 11.93 100.00
35 INT1376 Binding of Trh 121 0.48 20 69.86 100.00
36 INT100384 Regulation of SNRNP70 24 0.60 11 3.56 100.00
37 INT264605 Negative_regulation of Binding of Htr3a 1 0.01 1.12 0.64 100.00
38 INT14194 Localization of Azi1 1 0.01 0 0.49 100.00
39 INT11042 Localization of Tbxa2r 26 0.76 10.15 7.24 100.00
40 INT9032 Regulation of Htr2c 11 0.60 2.77 7.81 100.00
41 INT4656 Localization of RYBP 49 0.77 5.28 46.21 100.00
42 INT350 Localization of Th 79 0.80 10.26 41.17 100.00
43 INT2408 Regulation of CCK 37 0.61 10.01 26.66 100.00
44 INT48766 Regulation of NOS1 73 0.61 37.01 24.59 100.00
45 INT112338 Localization of Rvm 11 0.31 9.51 17.61 100.00
46 INT52403 Negative_regulation of HTR2B 5 0.42 1.79 3.15 100.00
47 INT95961 Localization of Htr1a 3 0.78 1.5 1.66 100.00
48 INT94532 Regulation of MT2A 5 0.36 4.25 0.98 100.00
49 INT115423 Gene_expression of Men1 4 0.47 14.08 0.64 100.00
50 INT340199 Regulation of Regulation of Smyd5 1 0.04 0.07 0.43 100.00
51 INT340205 Positive_regulation of Localization of Smyd5 1 0.08 0.34 0.38 100.00
52 INT340201 Positive_regulation of Localization of Htr1a 1 0.49 0.34 0.38 100.00
53 INT269274 Regulation of MTNR1A 3 0.60 1.47 0.05 100.00
54 INT264171 Positive_regulation of Positive_regulation of CD4 5 0.49 4.74 0.94 99.98
55 INT7234 Binding of GNRH1 43 0.47 21.59 12.36 99.98
56 INT241581 Regulation of Htr4 6 0.44 1.34 2.19 99.98
57 INT340196 Negative_regulation of Positive_regulation of Pttg1ip 1 0.33 1.32 0.84 99.98
58 INT18830 Localization of TBXA2R 25 0.81 7.14 9.28 99.98
59 INT25125 Localization of PLEKHM1 2 0.15 0.16 0.77 99.98
60 INT12975 Regulation of PLEK 21 0.60 13.62 8.28 99.96
61 INT235710 Binding of SSR1 2 0.36 0.86 1.75 99.96
62 INT27918 Positive_regulation of Klk1c7 6 0.36 2.89 2.84 99.92
63 INT32834 Negative_regulation of Klk1c7 7 0.31 2.17 2.15 99.92
64 INT84386 Positive_regulation of Positive_regulation of SRI 1 0.20 0 0.96 99.90
65 INT59969 Positive_regulation of Htr1a 12 0.67 5.07 5.73 99.90
66 INT79349 Gene_expression of Sert1 58 0.77 12.7 20.65 99.88
67 INT25057 Positive_regulation of Hmmr 14 0.28 5.09 9.63 99.88
68 INT100189 Negative_regulation of Gene_expression of Sert1 9 0.58 2.27 4.12 99.88
69 INT880 Positive_regulation of Localization of Gh1 304 0.70 14.79 150.23 99.84
70 INT64337 Negative_regulation of Negative_regulation of GRIN1 1 0.41 0 0.75 99.84
71 INT47710 Negative_regulation of GRIN1 71 0.57 25.57 34.24 99.84
72 INT49477 Gene_expression of Htr2c 12 0.75 3.26 5.73 99.84
73 INT62652 Binding of HTR7 9 0.47 2.79 3.06 99.84
74 INT876 Localization of Gh1 843 0.80 67.75 340.82 99.82
75 INT6623 Gene_expression of NA 231 0.78 45.78 59.36 99.82
76 INT71789 Positive_regulation of MAPK1 396 0.70 234.44 89.27 99.82
77 INT6791 Binding of NA 55 0.46 5.36 17.59 99.80
78 INT7000 Positive_regulation of Htr2a 42 0.67 9.48 18.7 99.80
79 INT7573 Positive_regulation of Nr3c2 38 0.67 20 21.84 99.76
80 INT13593 Binding of Prss12 13 0.36 4.35 9.37 99.76
81 INT7574 Positive_regulation of Transcription of Nr3c2 4 0.54 1.26 2.52 99.76
82 INT90315 Positive_regulation of Gene_expression of Nr3c2 4 0.55 2 1.83 99.76
83 INT27803 Regulation of ACOT1 16 0.38 5.94 4.64 99.76
84 INT20071 Positive_regulation of HTR2A 33 0.67 10.89 14 99.74
85 INT5916 Positive_regulation of HTR1A 51 0.67 18.27 21.38 99.72
86 INT340193 Positive_regulation of Pttg1ip 1 0.53 12.8 3.91 99.70
87 INT1044 Negative_regulation of Localization of LH 358 0.59 25.95 151.31 99.70
88 INT110284 Negative_regulation of Positive_regulation of Nr3c2 4 0.53 2.08 2.48 99.68
89 INT329032 Gene_expression of Tub 1 0.75 0.48 1.21 99.68
90 INT329029 Regulation of Gene_expression of Tub 1 0.44 0.07 0.3 99.68
91 INT6759 Regulation of Positive_regulation of Synm 1 0.21 0 2.19 99.66
92 INT15091 Gene_expression of SLC6A4 101 0.78 29.91 53.64 99.64
93 INT140670 Negative_regulation of Gene_expression of SLC6A4 4 0.51 2.7 3.88 99.64
94 INT340203 Regulation of Smyd5 1 0.07 1.5 1.34 99.64
95 INT5328 Positive_regulation of CD4 191 0.69 133.43 21.31 99.62
96 INT4449 Positive_regulation of NA 179 0.55 40.26 37.82 99.60
97 INT210838 Positive_regulation of Mc4r 17 0.53 6.79 3.06 99.60
98 INT5489 Localization of CA2 172 0.80 39.46 33.56 99.60
99 INT162903 Localization of PDE2A 2 0.61 0.89 0.45 99.60
100 INT4864 Regulation of BGLAP 22 0.34 10.8 5.07 99.58
101 INT52712 Negative_regulation of PRKCA 64 0.57 23.11 28.43 99.56
102 INT53495 Negative_regulation of Negative_regulation of PRKCA 4 0.42 2.37 3.18 99.56
103 INT36176 Negative_regulation of Gs 4 0.18 0.96 0.31 99.56
104 INT1045 Localization of LH 1211 0.81 87.04 456.25 99.54
105 INT65459 Binding of Racgap1 9 0.07 4.57 2.28 99.54
106 INT168677 Negative_regulation of ACOT1 14 0.27 6.29 3.52 99.52
107 INT300621 Localization of Men1 1 0.56 4.63 0.52 99.52
108 INT84965 Gene_expression of MAOA 15 0.75 6.9 6.06 99.50
109 INT6516 Positive_regulation of BGLAP 45 0.67 26.61 9.9 99.48
110 INT63932 Positive_regulation of Ephb1 537 0.70 259.67 296.14 99.48
111 INT14132 Negative_regulation of HTR1A 25 0.57 4.93 10.91 99.48
112 INT9282 Gene_expression of HTR1B 48 0.75 12.15 22.94 99.46
113 INT13286 Gene_expression of Ca2 317 0.67 71.58 65.01 99.44
114 INT66381 Regulation of Prkaca 40 0.62 13.38 27.96 99.44
115 INT17458 Negative_regulation of Gene_expression of FOS 98 0.57 36.77 55.69 99.44
116 INT70253 Negative_regulation of Gene_expression of Ca2 29 0.49 16.31 2.69 99.44
117 INT6513 Positive_regulation of Gene_expression of BGLAP 24 0.67 11.69 3.96 99.42
118 INT7340 Regulation of Grin1 87 0.62 30.37 57.93 99.42
119 INT30961 Binding of HTR2A 33 0.47 11.44 12.86 99.42
120 INT13790 Binding of HTR1A 52 0.47 18.83 17.59 99.42
121 INT6056 Negative_regulation of Gene_expression of Fos 601 0.59 193.05 386.84 99.42
122 INT7394 Positive_regulation of Localization of GNRH1 67 0.69 7.22 25.29 99.40
123 INT340187 Localization of Smyd5 1 0.12 0.28 0.32 99.40
124 INT7813 Regulation of SRI 25 0.61 6.18 8.13 99.38
125 INT14195 Localization of Pde2a 4 0.16 0.34 1.33 99.36
126 INT158 Localization of Prl 2431 0.81 378.96 952.2 99.34
127 INT100220 Negative_regulation of Src 13 0.41 6.37 4.93 99.34
128 INT65603 Positive_regulation of SRI 8 0.41 2.32 2.56 99.34
129 INT66261 Negative_regulation of Ccl21a 5 0.42 1.04 2.1 99.32
130 INT425 Localization of PRL 455 0.81 189.64 144.8 99.32
131 INT236000 Gene_expression of NPY6R 1 0.09 0 0.65 99.28
132 INT292 Localization of Penk 876 0.81 88.44 669.14 99.28
133 INT18755 Positive_regulation of Rvm 79 0.60 60 92.93 99.28
134 INT4957 Negative_regulation of Grin1 87 0.59 24.51 53.21 99.28
135 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02 99.26
136 INT93033 Negative_regulation of Grin2b 48 0.58 20.94 28.54 99.26
137 INT55552 Regulation of Gene_expression of Nr3c2 5 0.59 5.93 4.53 99.26
138 INT7180 Negative_regulation of Trib3 180 0.51 68.48 88.01 99.26
139 INT9079 Gene_expression of PPBP 52 0.75 31.2 21.52 99.20
140 INT33237 Regulation of Fst 10 0.39 1.3 3 99.18
141 INT6515 Gene_expression of BGLAP 110 0.75 45.13 10.81 99.16
142 INT15995 Positive_regulation of Alox5 18 0.49 3.94 4.63 99.16
143 INT10499 Positive_regulation of Cenpf 11 0.46 1.27 13.42 99.16
144 INT5356 Positive_regulation of FOS 153 0.69 54.21 56.74 99.14
145 INT4758 Positive_regulation of Localization of Calca 557 0.70 138.55 411.04 99.12
146 INT133678 Negative_regulation of NPY6R 2 0.20 0.74 1 99.12
147 INT6150 Positive_regulation of Negative_regulation of Calca 20 0.68 4.06 16.26 99.12
148 INT41340 Binding of Htr1a 5 0.47 0.76 3.16 99.10
149 INT132010 Localization of Atpif1 1 0.05 1.1 0.27 99.10
150 INT48718 Positive_regulation of PRKCA 109 0.69 36.16 46.49 99.08
151 INT12315 Gene_expression of Nr3c2 37 0.75 19.28 11.97 99.08
152 INT11554 Negative_regulation of CSF2 129 0.59 108.55 29.44 99.08
153 INT157 Positive_regulation of Localization of Prl 790 0.70 104.54 374.78 99.08
154 INT236002 Negative_regulation of Gene_expression of NPY6R 1 0.05 0 0.42 99.08
155 INT235996 Negative_regulation of Gene_expression of Src 3 0.09 1.29 0.58 99.08
156 INT29402 Gene_expression of Src 16 0.74 4.57 2.29 99.08
157 INT7571 Transcription of Nr3c2 6 0.58 2.15 3.03 99.08
158 INT28959 Negative_regulation of Rdbp 5 0.20 1.52 3.83 99.04
159 INT44998 Regulation of Eef1a2 6 0.42 2.37 2.65 99.00
160 INT6758 Positive_regulation of Synm 12 0.43 2.57 6.83 99.00
161 INT44997 Positive_regulation of Eef1a2 16 0.40 8.84 5.37 99.00
162 INT2520 Negative_regulation of Ca2 271 0.57 72.13 83.71 99.00
163 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08 98.96
164 INT14686 Localization of Trhr 1 0.56 0 2.33 98.96
165 INT79348 Positive_regulation of Sert1 11 0.64 4.32 6.17 98.86
166 INT4759 Negative_regulation of Localization of Calca 294 0.59 82.62 226.45 98.84
167 INT2540 Negative_regulation of Calca 538 0.59 172.11 384.38 98.84
168 INT106521 Negative_regulation of Tcrd 4 0.32 2.78 1.79 98.84
169 INT91913 Regulation of GRIN3B 16 0.61 11.48 14.44 98.84
170 INT139373 Gene_expression of Tcrd 1 0.50 0.85 0.25 98.84
171 INT261712 Regulation of GABRB3 6 0.09 3.03 3.14 98.80
172 INT5979 Gene_expression of Oprd1 428 0.78 75.64 320.32 98.76
173 INT7395 Localization of GNRH1 399 0.81 62.88 117.68 98.76
174 INT6293 Gene_expression of Oprm1 312 0.78 48.73 215.61 98.76
175 INT144702 Gene_expression of Tst 19 0.68 12.87 4.04 98.76
176 INT36173 Positive_regulation of Gs 17 0.43 7.48 8.19 98.76
177 INT186168 Negative_regulation of Negative_regulation of Grin2b 2 0.35 0.54 0.85 98.76
178 INT149015 Gene_expression of Tph2 20 0.78 9.45 10.4 98.74
179 INT2542 Localization of Calca 2008 0.81 518.3 1408.65 98.60
180 INT343582 Regulation of Gys1 1 0.03 0 1.1 98.60
181 INT17250 Negative_regulation of BGLAP 35 0.57 21 8.26 98.58
182 INT915 Positive_regulation of PRL 342 0.70 141.96 104.31 98.54
183 INT477 Localization of Avp 813 0.81 131.58 300.4 98.54
184 INT4358 Positive_regulation of Localization of Avp 195 0.70 30.79 77.58 98.54
185 INT7886 Regulation of Localization of Avp 146 0.62 14.53 72.99 98.54
186 INT148703 Gene_expression of NOVA2 73 0.65 18.05 8.3 98.48
187 INT66383 Phosphorylation of Prkaca 143 0.80 30.85 43.38 98.44
188 INT79805 Phosphorylation of PRKCA 57 0.81 23.33 20.41 98.44
189 INT26719 Negative_regulation of Gene_expression of Th 38 0.58 11.87 22.78 98.44
190 INT20003 Gene_expression of Scn2a1 125 0.71 8.78 23.94 98.40
191 INT75531 Regulation of MAPK1 70 0.61 34.39 15.42 98.40
192 INT190722 Positive_regulation of Gene_expression of Scn2a1 15 0.36 0.5 3.78 98.40
193 INT5050 Regulation of Localization of Calca 149 0.62 41.25 148.57 98.36
194 INT16253 Positive_regulation of Gene_expression of Bdnf 196 0.70 92.67 113.01 98.34
195 INT18148 Binding of Htr1f 4 0.47 2.05 3.23 98.28
196 INT96 Binding of Adrb1 18 0.48 2.8 8.52 98.28
197 INT42420 Negative_regulation of Binding of Adrb1 2 0.58 0.8 0.97 98.28
198 INT14853 Negative_regulation of Tac1 80 0.59 30.87 45.06 98.20
199 INT253 Regulation of PRL 184 0.62 47.27 65.79 98.18
200 INT1579 Gene_expression of PRL 279 0.78 119.2 55.41 98.18
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