P:ASIC

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pChart

Pain Term
Category Family
Synonyms Acid Sensing Channels, Amiloride Blockable Proton Gated Ion Channels, Amiloride-blockable Proton-gated Ion Channels, ASICs
Pain Specific No
Documents 197
Hot Single Events 200
Hot Interactions 58

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for ASIC. They are ordered first by their pain relevance and then by number of times they were reported for ASIC. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT98525 Binding of Accn2 and Accn3 1 0.01 0.38 0.68 100.00
2 INT153650 Accn4 Positive_regulation of Regulation of ASIC1 1 0.12 0.1 0.33 100.00
3 INT153651 Accn4 Regulation of ASIC1 1 0.08 0.08 0.31 100.00
4 INT107246 Ngf Regulation of Transcription of ASIC1 1 0.01 0.57 0.81 100.00
5 INT140802 Accn2 Regulation of Transcription of Accn1 1 0.24 0 0.36 100.00
6 INT147033 Positive_regulation of Binding of Sds and Accn3 1 0.13 0.73 1.23 100.00
7 INT147032 Binding of Sds and Accn3 1 0.09 0.73 1.22 100.00
8 INT330795 Positive_regulation of Accn2 Positive_regulation of Positive_regulation of Ca2 1 0.03 0 0.18 100.00
9 INT330798 Fig4 Negative_regulation of Gene_expression of Accn2 1 0.03 0 0.16 100.00
10 INT152282 Binding of Accn1 and Trpv1 1 0.10 0.42 0.49 100.00
11 INT152281 Binding of P2rx1 and Trpv1 1 0.15 0.42 0.49 100.00
12 INT276863 Gpr65 Regulation of Trpv1 1 0.25 1.78 1.75 99.84
13 INT354723 Binding of ASIC3 and Myo18a 1 0.00 0.25 0.23 99.36
14 INT166625 Acer3 Positive_regulation of Trpa1 1 0.01 1.91 1 99.36
15 INT354718 Binding of INADL and Myo18a 1 0.00 0.13 0.12 99.36
16 INT106117 Pick1 Positive_regulation of ASIC2 1 0.14 0.09 0.39 98.84
17 INT285184 Negative_regulation of Atp2a2 Negative_regulation of Localization of Ca2 1 0.04 0.66 0.05 98.00
18 INT106114 Binding of ASIC2 and Pick1 1 0.14 0.1 0.4 97.24
19 INT354206 Arc Positive_regulation of Accn2 1 0.02 0.57 0.42 97.04
20 INT354221 Igfbp7 Positive_regulation of Accn2 1 0.11 0.57 0.42 97.04
21 INT106116 Binding of ASIC1 and Pick1 1 0.04 0.1 0.4 96.80
22 INT354218 Igfbp7 Positive_regulation of Accn1 1 0.04 0.74 0.44 96.72
23 INT354217 Arc Positive_regulation of Accn1 1 0.01 0.29 0.21 96.72
24 INT330797 Positive_regulation of Accn2 Positive_regulation of Ca2 1 0.03 0 0.23 95.76
25 INT285183 Cd2 Regulation of Ca2 1 0.30 0.23 0.18 95.72
26 INT354710 Pick1 Regulation of ASIC1 1 0.37 1.12 0.21 94.88
27 INT153648 Binding of Accn4 and Ubb 1 0.01 0.09 0.35 93.80
28 INT354216 Binding of Accn3 and Positive_regulation of Gene_expression of Accn1 1 0.06 0.29 0.2 93.56
29 INT354220 Igfbp7 Positive_regulation of Gene_expression of Accn3 1 0.33 0.29 0.2 93.08
30 INT354225 Accn3 Positive_regulation of Gene_expression of Accn1 1 0.06 0.29 0.2 93.08
31 INT354226 Arc Positive_regulation of Gene_expression of Accn3 1 0.06 0.29 0.2 93.08
32 INT186566 Hpcl1 Positive_regulation of Fos 1 0.17 0.38 4.49 92.72
33 INT354211 Igfbp7 Positive_regulation of Gene_expression of Accn1 1 0.04 0.29 0.2 92.64
34 INT354214 Arc Positive_regulation of Gene_expression of Accn1 1 0.01 0.29 0.2 92.64
35 INT354717 Binding of ASIC1 and Dlg4 1 0.02 0 0.11 91.32
36 INT354223 Binding of Car2 and Igfbp7 1 0.02 0.4 0.19 89.28
37 INT120820 Binding of ASIC3 and Dlg4 3 0.02 0.11 0.84 89.12
38 INT354705 Binding of ASIC2 and Dlg4 1 0.00 0.11 0.12 89.12
39 INT354698 Binding of Dlg4 and Gopc 1 0.02 0.11 0.12 89.12
40 INT354719 Binding of ASIC1 and Pick1 1 0.40 2.34 0.4 88.64
41 INT354682 Binding of ASIC1 and PKN1 1 0.01 0.19 0.04 88.64
42 INT145775 Ngf Positive_regulation of Trpv1 11 0.72 7.71 11.25 88.36
43 INT296475 Binding of Pick1 and Myo18a 2 0.01 1.63 0.57 88.20
44 INT354703 Binding of ASIC1 and Myo18a 1 0.00 1.11 0.17 88.20
45 INT354715 Binding of PKN1 and Pick1 1 0.01 0.19 0.04 87.76
46 INT140004 Srxn1 Negative_regulation of Accn2 1 0.01 0.47 0.83 87.60
47 INT354714 Binding of ASIC3 and Gopc 1 0.08 0.1 0.11 85.68
48 INT354702 Binding of ASIC2 and Gopc 1 0.07 0.1 0.11 85.68
49 INT354210 Binding of Igfbp7 and Accn3 1 0.27 3.91 1.64 84.40
50 INT330796 P2ry1 Positive_regulation of Ca2 1 0.05 0.06 0.5 84.36
51 INT219915 Edn1 Regulation of Positive_regulation of Trpv1 1 0.33 0 0.18 83.16
52 INT354207 Igfbp7 Positive_regulation of Accn3 1 0.52 6.55 3.24 82.76
53 INT186567 Negative_regulation of Hpcl1 Positive_regulation of Fos 1 0.11 0.07 0.82 82.72
54 INT354713 Pick1 Regulation of Localization of ASIC1 1 0.22 0.48 0.08 82.00
55 INT354721 Pick1 Regulation of Gene_expression of ASIC1 1 0.37 1.1 0.2 82.00
56 INT130974 Slc9a3r1 Positive_regulation of ASIC3 1 0.08 0.29 0.36 81.80
57 INT106115 Pick1 Positive_regulation of Phosphorylation of ASIC2 1 0.13 0.07 0.39 80.52
58 INT166624 Acer3 Positive_regulation of Acer3 Positive_regulation of Trpa1 1 0.00 0.78 0.37 80.32
59 INT354712 Pick1 Positive_regulation of Gene_expression of ASIC1 1 0.39 0.74 0.11 79.20
60 INT354709 Gene_expression of Pick1 Positive_regulation of ASIC1 1 0.39 0.17 0.04 78.52
61 INT354213 Igfbp7 Regulation of Accn3 1 0.18 0.17 0.08 78.16
62 INT196883 Prkca Regulation of P2rx1 1 0.05 0.45 0.31 76.76
63 INT122271 Binding of ASIC2 and ASIC1 1 0.26 0.14 0.13 76.48
64 INT284855 Binding of S100a10 and Nav1 4 0.21 0.99 0.88 76.16
65 INT242613 Binding of Gfra2 and Ret 1 0.02 0 0.52 75.48
66 INT242628 Binding of Gfra1 and Ret 1 0.03 0 0.46 75.48
67 INT242615 Ret Positive_regulation of Gene_expression of Gfra1 1 0.04 0 0.46 75.48
68 INT242596 Binding of Ntrk1 and Ret 1 0.12 0 0.46 75.48
69 INT242631 Binding of Gfra2 and Ntrk1 1 0.01 0 0.52 74.80
70 INT242634 Binding of Gfra1 and Ntrk1 1 0.02 0 0.46 74.80
71 INT130975 Binding of ASIC3 and Slc9a3r1 1 0.06 0.26 0.43 72.68
72 INT208621 Binding of Prph and Nmbr 1 0.05 0.43 1.12 70.24
73 INT354704 Binding of MAP3K1 and Pick1 1 0.00 0.76 0.41 68.08
74 INT219913 Fig4 Positive_regulation of Trpv1 1 0.03 0 0.13 67.52
75 INT219920 EDNRA Positive_regulation of Trpv1 1 0.14 0 0.13 67.52
76 INT354209 Igfbp7 Regulation of Positive_regulation of Accn3 1 0.29 0.15 0.07 67.32
77 INT354215 Binding of Car2 and Accn3 1 0.03 0.21 0.1 66.48
78 INT161079 Mcs18 Negative_regulation of Trpv1 1 0.40 0.82 1.9 66.32
79 INT296458 Binding of Gria2 and Pick1 3 0.24 1.86 1.07 62.28
80 INT354697 Positive_regulation of Binding of Gria2 and Pick1 1 0.08 0.73 0.33 62.28
81 INT262577 Localization of Ngf Positive_regulation of Positive_regulation of Mapk14 1 0.05 0.92 0.75 60.56
82 INT137869 Gene_expression of Artn Positive_regulation of Gene_expression of Trpa1 1 0.52 0.16 0.17 56.84
83 INT137871 Gene_expression of Artn Positive_regulation of Gene_expression of Trpv1 1 0.74 0.16 0.17 56.44
84 INT354224 Bdnf Positive_regulation of Transcription of Accn3 1 0.09 1.04 0.95 55.64
85 INT101371 Inadl Positive_regulation of Gene_expression of ASIC3 1 0.02 0.46 0.27 51.76
86 INT240726 Binding of Esr1 and Ca2 1 0.02 0.57 0.05 51.72
87 INT330794 Positive_regulation of Gabrd Positive_regulation of Localization of Bdnf 1 0.02 0.78 0.33 49.76
88 INT284860 Binding of Pdzd2 and Nav1 9 0.29 2.33 2.34 45.84
89 INT342694 Binding of Pdzd2 and Gopc 1 0.03 0.15 0.1 45.84
90 INT342690 Binding of Sft2d3 and Pdzd2 1 0.00 0.15 0.09 45.84
91 INT342692 Binding of Gopc and Nav1 1 0.02 0.15 0.1 44.52
92 INT285185 Binding of Ca2 and Cd2 1 0.25 0.24 1.21 43.48
93 INT307100 Trpv1 Regulation of Binding of Trpa1 1 0.31 1.81 0.97 43.04
94 INT307103 Trpa1 Regulation of Binding of Trpv1 1 0.31 1.81 0.97 43.04
95 INT354700 Binding of Pick1 and Bfar 1 0.05 0.9 0.19 38.88
96 INT137870 Binding of Artn and Ret 1 0.25 0.16 0.05 36.16
97 INT342691 Pdzd2 Regulation of Nav1 1 0.19 0.48 0.34 33.68
98 INT262568 Prkaca Regulation of Trpv1 2 0.10 0.65 1.38 24.04
99 INT354701 Myo18a Positive_regulation of Binding of ASIC1 and Pick1 1 0.00 0.54 0.09 22.52
100 INT354695 ASIC1 Positive_regulation of Binding of ASIC1 and Pick1 1 0.37 0.54 0.09 22.52
101 INT219918 Positive_regulation of EDNRA Positive_regulation of Trpv1 1 0.13 0 0.26 22.48
102 INT354208 Arc Positive_regulation of Accn3 1 0.08 0.97 0.42 21.84
103 INT276865 Regulation of Trpv1 Regulation of Gene_expression of Gpr65 1 0.25 0.62 0.76 19.20
104 INT196879 Cpox Negative_regulation of Gene_expression of Tbxa2r 1 0.04 0.8 0.56 18.76
105 INT354711 Regulation of Binding of ASIC1 and Pick1 1 0.51 0.19 0.03 17.80
106 INT354716 Pick1 Regulation of Binding of ASIC1 1 0.37 0.2 0.03 13.64
107 INT354699 Binding of Accn2 and Pick1 1 0.07 0.22 0 8.44
108 INT188842 Accn3 Positive_regulation of Calca 1 0.08 0.46 0.25 7.44
109 INT354724 Bfar Regulation of Gene_expression of ASIC1 1 0.06 0.23 0.03 5.64
110 INT77646 Binding of Ngf and Ntrk1 23 0.40 7.85 9.26 5.00
111 INT106559 Binding of Bdnf and Ntrk2 23 0.43 11.09 7.33 5.00
112 INT84921 Binding of NGF and NTRK1 13 0.50 6.39 6.1 5.00
113 INT127128 Binding of CNR1 and CNR2 8 0.39 3.98 3.97 5.00
114 INT13966 Calca Positive_regulation of Localization of Sst 5 0.49 0.75 3.91 5.00
115 INT106560 Binding of Ntf3 and Ntrk2 3 0.14 2.47 2.84 5.00
116 INT220062 Binding of NGF and TNFRSF1B 1 0.10 2.21 2.81 5.00
117 INT220061 Binding of TRPV1 and TRPA1 1 0.15 1.7 2.69 5.00
118 INT103548 Binding of TRPV1 and TRPV3 3 0.37 1.82 2.28 5.00
119 INT117794 Hpcl1 Positive_regulation of Gene_expression of Fos 3 0.17 0.15 1.98 5.00
120 INT262558 Phax Positive_regulation of Trpv1 1 0.01 1.26 1.92 5.00
121 INT93293 Ngf Regulation of Trpv1 2 0.28 0.71 1.9 5.00
122 INT13979 Gast Positive_regulation of Localization of Sst 3 0.69 0.05 1.75 5.00
123 INT136034 Edn1 Regulation of Trpv1 2 0.66 0.39 1.58 5.00
124 INT208980 Binding of Ca2 and Trpv1 4 0.32 0.67 1.55 5.00
125 INT220058 NGF Positive_regulation of Gene_expression of BDNF 1 0.12 1.31 1.48 5.00
126 INT220059 NGF Positive_regulation of Positive_regulation of BDNF 1 0.11 1.31 1.48 5.00
127 INT121226 Ngf Regulation of Gene_expression of Trpv1 2 0.62 0.7 1.44 5.00
128 INT220060 Negative_regulation of Binding of NGF and NTRK1 1 0.08 1.11 1.39 5.00
129 INT242605 Gdnf Positive_regulation of Trpv1 1 0.26 0.17 1.3 5.00
130 INT242623 Binding of Ntf3 and Ntrk3 5 0.22 1.31 1.29 5.00
131 INT242625 Gdnf Positive_regulation of Pax3 1 0.01 0.34 1.15 5.00
132 INT242624 Binding of Ngf and Ntrk2 5 0.24 0.48 1.11 5.00
133 INT242642 Binding of BDNF and Ngfr 2 0.21 1.38 1.01 5.00
134 INT276864 Positive_regulation of Gpr65 Positive_regulation of Prkaca 1 0.16 0.74 0.97 5.00
135 INT258170 Binding of Adora1 and Ppap2a 1 0.05 0.26 0.94 5.00
136 INT186568 Hpcl1 Regulation of Gene_expression of Fos 1 0.22 0.07 0.94 5.00
137 INT242621 Gdnf Positive_regulation of Gene_expression of Scn11a 1 0.05 0.12 0.88 5.00
138 INT262572 Ngf Positive_regulation of Mapk1 2 0.04 0.52 0.81 5.00
139 INT262564 Ngf Positive_regulation of Pik3r1 1 0.08 0.36 0.8 5.00
140 INT219911 Edn1 Regulation of Gene_expression of Trpv1 1 0.23 0.57 0.8 5.00
141 INT262579 Ngf Positive_regulation of Prkca 1 0.07 0.36 0.8 5.00
142 INT220056 Binding of NTF3 and NTRK1 1 0.07 1.12 0.78 5.00
143 INT262582 F2rl1 Regulation of Positive_regulation of Prkca 1 0.03 0.58 0.78 5.00
144 INT220063 Binding of NTF3 and NTRK2 1 0.09 1.13 0.78 5.00
145 INT262562 F2rl1 Regulation of Trpv1 1 0.12 0.58 0.77 5.00
146 INT242626 Binding of Ngf and Ntrk3 3 0.15 0.27 0.77 5.00
147 INT220057 Binding of NTS and TNFRSF1B 1 0.08 1.23 0.76 5.00
148 INT262563 Negative_regulation of Pax3 Regulation of Calca 1 0.01 0.75 0.76 5.00
149 INT262569 Pax3 Regulation of Calca 1 0.00 0.75 0.76 5.00
150 INT262578 Prkaca Positive_regulation of Localization of Calca 1 0.03 0.71 0.75 5.00
151 INT219914 Prkcg Regulation of Phosphorylation of Trpv1 1 0.11 1 0.74 5.00
152 INT262573 Par2 Regulation of Positive_regulation of Prkca 1 0.05 0.57 0.72 5.00
153 INT262580 Ngf Positive_regulation of Hspg2 1 0.03 0.35 0.72 5.00
154 INT262581 Prkca Positive_regulation of Phosphorylation of Trpv1 1 0.13 0.28 0.71 5.00
155 INT262574 Gnaq Positive_regulation of Prkca 1 0.00 0.57 0.71 5.00
156 INT262566 Par2 Regulation of Trpv1 1 0.20 0.57 0.71 5.00
157 INT262571 Phosphorylation of Trpv1 Positive_regulation of Localization of Calca 1 0.17 0.71 0.7 5.00
158 INT262570 Binding of Pax3 and Trpv1 1 0.02 1.05 0.67 5.00
159 INT262576 Binding of Calca and Trpv1 1 0.13 1.05 0.66 5.00
160 INT186569 Regulation of Hpcl1 Positive_regulation of Fos 1 0.07 0 0.65 5.00
161 INT242635 Binding of Bdnf and Ntrk3 3 0.25 0.98 0.64 5.00
162 INT219921 EDNRA Negative_regulation of Trpv1 1 0.13 0.36 0.63 5.00
163 INT219919 EDNRA Negative_regulation of Edn1 1 0.15 0.36 0.63 5.00
164 INT196877 Trpv1 Positive_regulation of Localization of Calca 1 0.11 0.41 0.62 5.00
165 INT324065 Ptger2 Positive_regulation of Prkaca 2 0.24 0.63 0.61 5.00
166 INT252869 Binding of Trpv1 and Phax 2 0.01 0.18 0.6 5.00
167 INT242584 Gdnf Regulation of Gene_expression of Qrfp 1 0.00 0.09 0.58 5.00
168 INT242602 Binding of Ntf3 and Ntrk1 1 0.10 0.14 0.57 5.00
169 INT242614 Binding of Gdnf and Gfra1 1 0.03 0 0.51 5.00
170 INT342689 Ptger4 Positive_regulation of Prkaca 1 0.03 0.24 0.51 5.00
171 INT242598 Binding of Gdnf and Gfra2 4 0.16 0.38 0.51 5.00
172 INT262565 Prkaca Regulation of Negative_regulation of Trpv1 1 0.05 0.21 0.5 5.00
173 INT242597 Gene_expression of Gdnf Negative_regulation of Trpv1 1 0.27 0.08 0.5 5.00
174 INT242638 Binding of BDNF and Gdnf 1 0.29 0 0.49 5.00
175 INT242600 Binding of Gdnf and Gopc 1 0.06 0 0.49 5.00
176 INT242604 Gdnf Regulation of Gene_expression of Trpv1 1 0.17 0.36 0.48 5.00
177 INT342693 Binding of Prkaca and Gopc 1 0.01 0.23 0.48 5.00
178 INT219910 EDN1 Positive_regulation of Positive_regulation of EDNRA 1 0.00 0.3 0.45 5.00
179 INT262575 Trpv1 Positive_regulation of Prkca 1 0.13 0.17 0.44 5.00
180 INT196881 Ly6 Positive_regulation of Prkca 2 0.01 0.25 0.42 5.00
181 INT316632 Dao Negative_regulation of Gopc 1 0.09 0 0.4 5.00
182 INT242607 Negative_regulation of Ntrk1 Positive_regulation of Ret 1 0.16 0 0.39 5.00
183 INT208623 Nmbr Positive_regulation of Prph 1 0.04 0.15 0.36 5.00
184 INT342687 Pdzd2 Regulation of Gene_expression of Nav1 1 0.19 0.3 0.35 5.00
185 INT242616 Gfra1 Regulation of Gene_expression of Gfra2 1 0.00 0 0.34 5.00
186 INT258171 Binding of Asap1 and Adp 1 0.04 0 0.31 5.00
187 INT242622 Binding of Bdnf and Ntrk1 1 0.05 0.07 0.29 5.00
188 INT342151 Sst Regulation of Localization of Gast 1 0.04 0 0.26 5.00
189 INT196886 Ly6 Positive_regulation of Binding of Ly6 and Prkca 1 0.00 0.18 0.25 5.00
190 INT196880 Binding of Ly6 and Prkca 1 0.01 0.18 0.25 5.00
191 INT242595 Trpm8 Negative_regulation of Trpv1 1 0.24 0 0.23 5.00
192 INT242632 Ret Positive_regulation of Gene_expression of Trpa1 1 0.33 0.09 0.18 5.00
193 INT242629 Ngf Regulation of Gene_expression of Gfra2 1 0.02 0 0.18 5.00
194 INT242603 Binding of Gfra1 and Gopc 1 0.01 0 0.17 5.00
195 INT242617 Binding of Gfra2 and Gopc 1 0.01 0 0.17 5.00
196 INT242610 Binding of Gfra2 and Nrtn 1 0.02 0 0.17 5.00
197 INT342152 Binding of Casr and Positive_regulation of Localization of Sst 1 0.07 0.29 0.17 5.00
198 INT242641 Binding of BDNF and Gfra2 1 0.03 0 0.17 5.00
199 INT242640 Binding of BDNF and Gfra1 1 0.05 0 0.17 5.00
200 INT242606 Binding of Gfra1 and Nrtn 1 0.03 0 0.17 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for ASIC. They are ordered first by their pain relevance and then by number of times they were reported in ASIC. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT98521 Gene_expression of Accn2 52 0.74 23.45 35.09 100.00
2 INT98524 Positive_regulation of Accn2 15 0.49 9.48 11.57 100.00
3 INT81088 Gene_expression of ASIC1 26 0.77 17.8 15.07 100.00
4 INT68290 Gene_expression of Accn1 32 0.73 7.36 11.23 100.00
5 INT98522 Gene_expression of Accn3 68 0.78 26.95 28.6 100.00
6 INT120651 Positive_regulation of Gene_expression of Accn2 13 0.66 9.02 8.58 100.00
7 INT126989 Transcription of Accn2 8 0.63 5.22 6.77 100.00
8 INT147028 Negative_regulation of Accn2 6 0.14 2.06 3.92 100.00
9 INT93191 Gene_expression of Accn2 22 0.76 10.04 8.91 100.00
10 INT295924 Regulation of Gene_expression of Accn2 5 0.14 2.82 2.62 100.00
11 INT81087 Gene_expression of ASIC3 30 0.75 13.62 16.54 100.00
12 INT104902 Regulation of ASIC1 6 0.51 5.17 3.13 100.00
13 INT73223 Gene_expression of UPF1 78 0.41 31.44 9.94 100.00
14 INT81089 Positive_regulation of ASIC1 14 0.65 4.42 3.82 100.00
15 INT166766 Regulation of Accn2 2 0.11 2.02 2.16 100.00
16 INT64202 Positive_regulation of Trpv1 643 0.70 249.66 397.42 100.00
17 INT142310 Negative_regulation of Gene_expression of Accn2 3 0.30 2.07 2.64 100.00
18 INT93198 Transcription of ASIC1 7 0.62 1.96 3.04 100.00
19 INT93195 Negative_regulation of Accn2 14 0.59 7.23 6.31 100.00
20 INT72256 Binding of Accn3 6 0.47 2.01 3.2 100.00
21 INT75551 Localization of Accn1 6 0.68 1.75 2.58 100.00
22 INT93200 Gene_expression of ASIC2 6 0.60 3.27 3.7 100.00
23 INT93193 Positive_regulation of Accn2 16 0.69 7.2 6.37 100.00
24 INT109578 Positive_regulation of Accn3 16 0.70 9.09 10.05 100.00
25 INT129154 Positive_regulation of Pirt 8 0.02 1.61 3.18 100.00
26 INT109577 Positive_regulation of Gene_expression of Accn3 9 0.67 4.77 5.76 100.00
27 INT93196 Negative_regulation of ASIC1 7 0.43 2.97 2 100.00
28 INT98523 Localization of Accn2 4 0.22 1.07 2.16 100.00
29 INT72253 Positive_regulation of Accn1 8 0.63 2.64 2.73 100.00
30 INT131136 Binding of Accn2 3 0.36 1.44 1.23 100.00
31 INT12029 Gene_expression of Car1 143 0.67 29.69 36.39 100.00
32 INT112703 Binding of Accn2 4 0.37 0.64 1.19 100.00
33 INT129155 Negative_regulation of Accn3 4 0.46 1.36 2.07 100.00
34 INT49520 Gene_expression of P2rx3 121 0.78 61.15 49.24 100.00
35 INT295922 Positive_regulation of Transcription of Accn2 1 0.14 2.19 1.45 100.00
36 INT147029 Positive_regulation of Accn4 2 0.19 1.26 1.73 100.00
37 INT81086 Positive_regulation of Accn1 8 0.65 7.51 4.62 100.00
38 INT77515 Positive_regulation of ASIC3 12 0.67 3.67 4.19 100.00
39 INT147030 Positive_regulation of Positive_regulation of Accn2 3 0.21 1.44 1.94 100.00
40 INT136496 Regulation of Accn3 5 0.45 3.72 6.53 100.00
41 INT38731 Localization of Trpv1 138 0.81 52.73 90.49 100.00
42 INT136190 Transcription of Accn1 5 0.61 2.75 2.24 100.00
43 INT107245 Binding of ASIC1 4 0.00 1.82 1.63 100.00
44 INT159464 Negative_regulation of Accn1 4 0.37 1.07 1.41 100.00
45 INT41541 Regulation of Gene_expression of Car1 9 0.41 3.82 3.52 100.00
46 INT87687 Positive_regulation of Trpv1 409 0.70 210.24 257.59 100.00
47 INT295923 Gene_expression of Bcl2l2 1 0.09 0.71 0.65 100.00
48 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03 100.00
49 INT76531 Transcription of Trpv1 62 0.72 23.69 34.77 100.00
50 INT98514 Positive_regulation of Gene_expression of ASIC1 2 0.57 3.83 2.2 100.00
51 INT13145 Positive_regulation of Car1 60 0.70 16.32 23.23 100.00
52 INT165081 Positive_regulation of Positive_regulation of Accn2 3 0.49 2.79 1.9 100.00
53 INT220070 Negative_regulation of ASIC2 1 0.02 1.09 1.39 100.00
54 INT109061 Gene_expression of PRKD1 5 0.58 1.8 3.04 100.00
55 INT143673 Regulation of Gene_expression of Accn1 4 0.43 0.81 0.78 100.00
56 INT45961 Gene_expression of Cspg4 22 0.78 7.21 3.43 100.00
57 INT101369 Binding of ASIC3 3 0.32 1.11 2.5 100.00
58 INT68289 Positive_regulation of Gene_expression of Accn1 2 0.45 0.34 0.83 100.00
59 INT35634 Positive_regulation of Gene_expression of Sds 10 0.37 3.23 3.69 100.00
60 INT91914 Binding of Accn1 3 0.36 0.44 1.24 100.00
61 INT107244 Positive_regulation of Transcription of ASIC1 1 0.03 0.46 0.79 100.00
62 INT141743 Positive_regulation of Positive_regulation of Accn3 2 0.39 1.11 1.19 100.00
63 INT93308 Gene_expression of PIRT 13 0.09 2 2.92 100.00
64 INT140800 Negative_regulation of Gene_expression of Accn1 1 0.40 0.08 0.33 100.00
65 INT9381 Positive_regulation of TRPV1 523 0.70 187.4 276.05 100.00
66 INT283147 Gene_expression of SCNN1B 1 0.09 0.26 0.3 100.00
67 INT192371 Positive_regulation of Accn5 1 0.05 0.09 0.28 100.00
68 INT165082 Regulation of Gene_expression of Accn2 1 0.27 1.64 1.4 100.00
69 INT285182 Negative_regulation of Accn1 1 0.04 1.06 0.31 100.00
70 INT119656 Regulation of Accn1 1 0.31 0.2 0.33 100.00
71 INT25251 Binding of Fos 19 0.36 7.96 3.73 100.00
72 INT103319 Regulation of Positive_regulation of Trpv1 11 0.45 8.37 5.99 100.00
73 INT97237 Transcription of TRPV1 33 0.72 10.56 12.4 100.00
74 INT42943 Positive_regulation of Atrn 9 0.18 2.68 3.43 100.00
75 INT188159 Positive_regulation of Positive_regulation of P2rx3 1 0.20 0.74 0.75 100.00
76 INT117422 Gene_expression of Pirt 13 0.33 2.17 5.23 99.98
77 INT151733 Gene_expression of OR4G3P 2 0.34 0.23 0.3 99.98
78 INT115071 Positive_regulation of Accn3 14 0.70 16.56 14.24 99.96
79 INT72250 Binding of Accn1 3 0.44 2.87 1.27 99.96
80 INT58061 Gene_expression of Trpv1 1117 0.78 451.54 637.59 99.92
81 INT92105 Transcription of Trpv1 47 0.71 27.47 25.01 99.92
82 INT76660 Gene_expression of Trpv1 691 0.78 329.46 386.42 99.84
83 INT19948 Gene_expression of Sds 34 0.63 14.69 15.44 99.82
84 INT60126 Regulation of Trpv1 186 0.62 85.53 133.4 99.80
85 INT98498 Binding of Trpv1 75 0.48 33.67 44.4 99.80
86 INT154198 Binding of Pick1 9 0.48 6.91 3.16 99.76
87 INT3969 Positive_regulation of Sds 27 0.69 7.52 12.31 99.74
88 INT17028 Positive_regulation of Scn7a 35 0.41 9.83 7.44 99.66
89 INT8528 Negative_regulation of Gene_expression of Fos 100 0.59 41.15 55.6 99.62
90 INT1033 Positive_regulation of Ca2 507 0.68 131.76 147.64 99.60
91 INT6782 Gene_expression of SCN5A 156 0.78 33.13 17.88 99.60
92 INT5380 Positive_regulation of Gene_expression of Fos 243 0.70 105.65 131.05 99.52
93 INT5379 Gene_expression of Fos 656 0.78 255.5 292.54 99.52
94 INT78233 Positive_regulation of P2rx3 36 0.56 21.49 17.25 99.52
95 INT147718 Positive_regulation of Cspg4 4 0.50 2.61 1.53 99.46
96 INT170025 Gene_expression of Fig4 588 0.67 183.27 113.32 99.44
97 INT12476 Negative_regulation of TRPV1 124 0.59 47.95 77.98 99.42
98 INT4843 Gene_expression of Npff 50 0.78 12.92 36.37 99.36
99 INT354203 Regulation of Igfbp7 1 0.26 0.38 0.24 99.32
100 INT6623 Gene_expression of NA 231 0.78 45.78 59.36 99.22
101 INT233457 Gene_expression of Gpr65 56 0.68 26.57 27.94 99.20
102 INT130785 Regulation of Arc 9 0.62 5.56 2.2 99.18
103 INT170646 Negative_regulation of Fig4 213 0.37 81.29 46.92 99.16
104 INT64201 Negative_regulation of Trpv1 203 0.59 79.18 119.75 99.06
105 INT104899 Regulation of Accn2 5 0.39 3.47 2.07 98.96
106 INT109430 Positive_regulation of Trpa1 119 0.70 44 49.14 98.88
107 INT25363 Negative_regulation of Trpv1 144 0.59 64.78 75.7 98.56
108 INT11491 Positive_regulation of KNG1 128 0.67 60.41 58.74 98.56
109 INT100124 Gene_expression of Accn3 38 0.78 30.02 23.63 98.48
110 INT93197 Positive_regulation of ASIC2 7 0.61 1.94 2.79 98.40
111 INT14546 Positive_regulation of Localization of Ca2 93 0.67 31.09 18.72 98.36
112 INT92542 Negative_regulation of Trpv2 8 0.59 1.54 2.15 98.36
113 INT2520 Negative_regulation of Ca2 271 0.57 72.13 83.71 98.28
114 INT7458 Negative_regulation of Kcnma1 30 0.43 6.61 10.4 98.28
115 INT153649 Negative_regulation of Gene_expression of ASIC1 3 0.42 0.38 0.79 98.20
116 INT52591 Gene_expression of KCNMA1 78 0.76 13.95 15.55 98.20
117 INT116321 Regulation of Nav1 38 0.62 26.62 37.97 98.12
118 INT101370 Regulation of CNGB3 2 0.00 0.56 0.72 98.08
119 INT4822 Localization of Ca2 417 0.80 99.57 96.45 98.00
120 INT208613 Localization of Nmbr 1 0.40 0.2 0.46 97.70
121 INT18357 Gene_expression of TRPV1 825 0.78 307.11 382.81 97.64
122 INT117421 Regulation of Pirt 2 0.00 1.44 2.3 97.56
123 INT30170 Gene_expression of Car2 330 0.66 77.26 46.76 97.48
124 INT170516 Negative_regulation of Gene_expression of Car2 35 0.35 9.4 5.48 97.48
125 INT148649 Transcription of P2rx2 8 0.43 8.11 4.79 97.28
126 INT136193 Positive_regulation of Gene_expression of Accn2 1 0.38 1.43 0.97 97.20
127 INT62960 Gene_expression of P2rx2 149 0.77 58.31 59.16 97.00
128 INT142815 Regulation of Regulation of P2rx2 4 0.33 0.69 1.33 96.92
129 INT26229 Positive_regulation of ATP8A2 6 0.67 2.1 4.48 96.92
130 INT101366 Regulation of Inadl 2 0.02 0.48 0.32 96.88
131 INT93192 Transcription of Accn2 5 0.52 4.63 4.79 96.84
132 INT165084 Transcription of Accn3 3 0.70 3.4 3.01 96.84
133 INT114446 Gene_expression of CAMK2D 2 0.01 0.59 0.36 96.68
134 INT117601 Positive_regulation of Trpa1 174 0.70 72.41 71.9 96.56
135 INT92839 Regulation of P2rx2 36 0.45 13.19 15.38 96.48
136 INT87686 Positive_regulation of Gene_expression of Trpv1 101 0.70 72.41 69.15 96.20
137 INT55255 Positive_regulation of Localization of Il6 48 0.69 24.88 12.76 96.04
138 INT276855 Positive_regulation of Gene_expression of Gpr65 1 0.61 17.04 16.96 95.92
139 INT186564 Gene_expression of Hpcl1 1 0.21 0.08 1.32 95.92
140 INT12161 Positive_regulation of P2rx2 70 0.69 34.22 34.4 95.88
141 INT81249 Positive_regulation of Trpv2 21 0.70 8.13 12.36 95.88
142 INT115070 Binding of Accn3 4 0.47 3.8 2.7 95.84
143 INT15127 Regulation of Cd2 4 0.44 1.06 2.38 95.72
144 INT49536 Regulation of Regulation of Ca2 6 0.38 3.89 1.13 95.48
145 INT135892 Localization of Accn2 4 0.74 2.23 2.12 95.32
146 INT1613 Binding of Nts 58 0.48 10.55 28.18 95.30
147 INT73429 Negative_regulation of Atp2a2 20 0.20 9.05 0.74 95.28
148 INT101368 Positive_regulation of Gene_expression of ASIC3 6 0.32 2.61 3.06 95.24
149 INT113625 Positive_regulation of Gene_expression of Ca2 47 0.50 9.82 14.07 95.08
150 INT80807 Positive_regulation of PDC 3 0.38 1.78 0.9 95.04
151 INT354691 Gene_expression of INADL 1 0.65 0.12 0.11 94.84
152 INT354690 Positive_regulation of Gene_expression of INADL 1 0.49 0.12 0.11 94.84
153 INT121416 Gene_expression of Trpm8 101 0.78 52.7 47.85 94.76
154 INT13286 Gene_expression of Ca2 317 0.67 71.58 65.01 94.72
155 INT95090 Gene_expression of ASIC4 2 0.67 1.28 0.66 94.68
156 INT19511 Localization of Il6 212 0.81 118.17 67.67 94.56
157 INT136614 Positive_regulation of Cav1 5 0.46 2.28 2.23 94.56
158 INT186562 Negative_regulation of Transcription of Nts 1 0.33 0.1 0.1 94.44
159 INT106106 Gene_expression of Pick1 3 0.70 0.66 0.68 94.32
160 INT78234 Positive_regulation of Gene_expression of P2rx2 18 0.69 12.86 12.75 94.24
161 INT96622 Localization of Trpv1 110 0.81 59.82 63.25 94.20
162 INT276836 Localization of Gpr65 1 0.70 1.19 1.03 94.20
163 INT21047 Transcription of Nts 20 0.69 4.55 8.5 94.20
164 INT76766 Transcription of ASIC2 2 0.24 0.08 0.79 94.12
165 INT81251 Gene_expression of Trpv2 78 0.78 28.27 41.76 94.12
166 INT114627 Positive_regulation of Gene_expression of Trpv2 9 0.70 6.41 5.18 94.12
167 INT154773 Regulation of Accn3 7 0.62 7.09 6.63 94.08
168 INT100126 Localization of Accn3 7 0.77 2.73 2.76 94.00
169 INT140798 Localization of Accn1 3 0.76 0.24 0.34 94.00
170 INT122053 Positive_regulation of P2rx4 16 0.69 13.02 11.98 93.92
171 INT1032 Regulation of Ca2 202 0.52 54.91 53.03 93.80
172 INT151732 Transcription of Accn4 1 0.52 0.08 0.35 93.64
173 INT136192 Negative_regulation of Gene_expression of Accn2 1 0.35 2.44 1.71 93.56
174 INT70816 Negative_regulation of Fos 32 0.58 13 11.18 93.56
175 INT121970 Negative_regulation of Transcription of Fos 4 0.42 2.52 1.48 93.56
176 INT3537 Positive_regulation of Car2 413 0.56 103.51 94.35 93.52
177 INT72251 Phosphorylation of Kcnma1 2 0.05 0.07 0.13 93.52
178 INT78817 Binding of Scnn1a 2 0.35 0 0.48 93.40
179 INT99951 Regulation of Accn1 5 0.26 2.65 2.1 93.20
180 INT98621 Regulation of Trpv1 121 0.62 79.24 75.23 93.20
181 INT276837 Positive_regulation of Transcription of Gpr65 1 0.61 1.76 1.62 92.72
182 INT276848 Transcription of Gpr65 1 0.63 1.75 1.61 92.72
183 INT286806 Negative_regulation of Gene_expression of Cspg4 2 0.26 1.15 0.19 92.64
184 INT166007 Negative_regulation of Gene_expression of Scnn1a 1 0.26 0.32 0.46 92.56
185 INT47766 Transcription of Fos 25 0.69 8.78 4.42 92.52
186 INT283143 Binding of PKD2L1 1 0.35 0 0.28 92.44
187 INT166006 Gene_expression of Scnn1a 2 0.46 0.32 0.83 92.32
188 INT283141 Transcription of PKD2L1 1 0.65 0 0.58 92.24
189 INT211008 Transcription of PKD1L3 2 0.60 0 0.61 92.24
190 INT354201 Positive_regulation of Igfbp7 1 0.40 5.32 2.87 92.20
191 INT166767 Negative_regulation of Gene_expression of Accn1 1 0.12 0.13 0.44 91.60
192 INT58062 Negative_regulation of Gene_expression of Trpv1 66 0.59 22.34 38.02 91.60
193 INT72254 Gene_expression of Accn1 9 0.71 3.24 2.46 91.56
194 INT95976 Gene_expression of Accn4 4 0.76 0.86 1.42 91.40
195 INT242545 Regulation of Regulation of Calca 1 0.15 0 0.36 91.40
196 INT142309 Regulation of Gene_expression of Accn3 2 0.50 1.34 1.16 91.24
197 INT6979 Positive_regulation of CA2 206 0.67 50.79 44.97 91.12
198 INT106113 Regulation of Positive_regulation of ASIC2 1 0.17 0.06 0.36 91.04
199 INT22499 Regulation of Calca 42 0.62 17.32 28.02 90.96
200 INT80075 Regulation of Gene_expression of Trpv1 55 0.62 32.42 36.88 90.84
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