P:Acute pain

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Pain Term
Category Pain type
Synonyms Warning Pain
Pain Specific Yes
Documents 3188
Hot Single Events 200
Hot Interactions 17

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Acute pain. They are ordered first by their pain relevance and then by number of times they were reported for Acute pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT139592 Ntsr1 Positive_regulation of Nts 1 0.09 0.17 0.79 95.80
2 INT139593 Ntsr1 Positive_regulation of Rbm39 1 0.01 0.17 0.79 95.68
3 INT298279 Pou4f1 Positive_regulation of Gene_expression of Runx3 1 0.50 1.31 0.81 92.88
4 INT298262 Pou4f1 Positive_regulation of Positive_regulation of Ntrk3 1 0.36 0.79 0.63 92.88
5 INT139594 Binding of Nts and Rbm39 1 0.02 0.19 0.87 91.76
6 INT152490 Slc40a1 Negative_regulation of Faah 1 0.01 0.73 0.98 90.72
7 INT321045 Anpep Positive_regulation of Protein_catabolism of Ptpn6 1 0.01 0.22 0.48 88.32
8 INT149281 Binding of MAPT and Dbp 1 0.00 0.4 0.17 87.36
9 INT160653 Binding of P2rx1 and Ptgfr 1 0.28 0.66 1.14 86.44
10 INT313375 Cnr2 Positive_regulation of Phosphorylation of Mapk14 1 0.18 0.39 0.5 86.00
11 INT313373 Cnr2 Positive_regulation of Gene_expression of Gfap 1 0.32 0.39 0.5 86.00
12 INT313376 Cnr1 Positive_regulation of Phosphorylation of Mapk14 1 0.20 0.38 0.5 84.96
13 INT313371 Cnr1 Positive_regulation of Gene_expression of Gfap 1 0.35 0.39 0.5 84.96
14 INT341897 Positive_regulation of NT5C3 Positive_regulation of Positive_regulation of Oxt 1 0.32 0.42 1.07 83.36
15 INT144050 IL4 Negative_regulation of Gene_expression of PTGES 1 0.27 0.48 0.35 80.92
16 INT144046 IL13 Negative_regulation of Gene_expression of PTGES 1 0.30 0.48 0.35 80.68
17 INT257302 Cnp Regulation of Protein_catabolism of Pde5a 1 0.05 0.49 0.7 80.24
18 INT144049 IL10 Negative_regulation of Gene_expression of PTGES 1 0.35 0.47 0.35 79.44
19 INT144045 IFNG Negative_regulation of Gene_expression of PTGES 1 0.63 0.47 0.35 79.08
20 INT103184 Prkaca Positive_regulation of Phosphorylation of CRTC1 1 0.01 0.57 0.55 79.00
21 INT96228 COX5A Regulation of Ak1 1 0.01 0.6 0.6 78.72
22 INT144048 IRF6 Positive_regulation of Gene_expression of PTGES 1 0.12 0.46 0.35 78.28
23 INT252857 Binding of F2rl1 and Trpa1 1 0.22 0.84 0.63 76.08
24 INT252859 Binding of Ngf and Trpa1 1 0.19 0.84 0.62 76.08
25 INT62018 CSF2 Regulation of ACOT1 1 0.12 0.47 1.21 75.00
26 INT62019 CSF2 Regulation of ELANE 1 0.03 0.47 1.21 75.00
27 INT62017 ELANE Positive_regulation of Localization of ACOT1 1 0.05 0.35 0.98 75.00
28 INT144047 IL4 Positive_regulation of PTGES 1 0.29 0.43 0.37 73.68
29 INT144044 IRF6 Positive_regulation of PTGES 1 0.10 0.43 0.37 73.68
30 INT144043 IL13 Positive_regulation of PTGES 1 0.32 0.43 0.37 73.68
31 INT284791 Binding of Trpv1 and DRGX 1 0.02 0.66 0.6 73.48
32 INT284792 Binding of Trpa1 and DRGX 1 0.02 0.66 0.6 73.48
33 INT136514 Binding of Grm1 and Grm5 4 0.12 1.8 3.9 72.48
34 INT117504 OPA1 Positive_regulation of CPP 1 0.09 1.09 1.13 71.36
35 INT132862 Ngf Positive_regulation of Bdnf 4 0.46 4.05 3.65 68.72
36 INT240658 Ngf Positive_regulation of Ngf Positive_regulation of Bdnf 1 0.33 1.67 1.99 68.72
37 INT112105 Negative_regulation of Dlg2 Negative_regulation of Gene_expression of Grin2b 2 0.40 0.89 1.2 67.84
38 INT112107 Negative_regulation of Dlg2 Negative_regulation of Gene_expression of Grin2a 1 0.40 0.49 0.57 67.84
39 INT165941 Bmp7 Positive_regulation of Penk 1 0.28 0.43 0.95 67.76
40 INT165942 Bmp7 Positive_regulation of Transcription of Pomc 1 0.29 0.43 0.95 67.76
41 INT165940 Bmp7 Positive_regulation of Pomc 1 0.29 0.43 0.95 67.76
42 INT195423 COMT Negative_regulation of GBE1 1 0.00 0.22 0.19 67.44
43 INT195424 SNRNP70 Negative_regulation of GBE1 1 0.00 0.22 0.19 67.44
44 INT112106 Negative_regulation of Dlg2 Negative_regulation of Grin2a 1 0.40 0.48 0.56 66.24
45 INT251146 Binding of Grin1 and Dlg2 1 0.36 1.95 3.16 64.88
46 INT261413 Positive_regulation of GRIN1 Positive_regulation of Positive_regulation of Creb1 1 0.00 0.81 0.77 63.52
47 INT240653 Ngf Positive_regulation of Positive_regulation of Bdnf 1 0.55 2.97 4.23 61.92
48 INT120732 Prkcg Positive_regulation of Phosphorylation of Grin1 2 0.48 1.04 1.81 61.32
49 INT186161 Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.11 1.05 1.01 61.32
50 INT89430 Binding of ICAM4 and ITGA4 1 0.05 0.48 0.06 59.04
51 INT186159 Grin2d Negative_regulation of Grin2b 1 0.21 0.82 0.62 57.92
52 INT68272 Binding of Oprd1 and G2e3 1 0.00 0.11 1.93 55.76
53 INT68273 G2e3 Negative_regulation of Binding of Oprd1 and G2e3 1 0.00 0.11 1.93 55.76
54 INT262581 Prkca Positive_regulation of Phosphorylation of Trpv1 1 0.13 0.28 0.71 52.32
55 INT107322 Positive_regulation of TRPV1 Positive_regulation of Localization of IL8 3 0.13 1.64 2.5 50.00
56 INT299985 BDKRB2 Regulation of Gene_expression of BDKRB1 1 0.21 0.75 1.16 50.00
57 INT299986 BDKRB2 Regulation of Gene_expression of SPANXB1 1 0.29 0.51 1.02 50.00
58 INT299988 IL6 Positive_regulation of Localization of IL8 1 0.05 0.81 0.94 50.00
59 INT299990 BDKRB2 Positive_regulation of TRPV1 1 0.43 0.74 0.84 50.00
60 INT299987 SPANXB1 Positive_regulation of TRPV1 1 0.20 0.71 0.82 50.00
61 INT299989 PRKCA Positive_regulation of Gene_expression of IL8 1 0.04 0.45 0.67 50.00
62 INT219274 Binding of Cx3cr1 and Cx3cl1 1 0.17 1.08 0.74 48.88
63 INT257577 CALCA Positive_regulation of DMD 1 0.01 0.57 0.26 46.48
64 INT277613 Binding of HDAC9 and Runx2 1 0.02 0.59 0.26 45.84
65 INT218838 Ppp1r9a Regulation of Cysltr1 1 0.01 1.2 0.63 44.32
66 INT218835 Ppp1cc Regulation of Cysltr1 1 0.01 1.19 0.62 44.32
67 INT218836 Binding of Ppp1cc and Regulation of Cysltr1 1 0.01 1.2 0.62 44.32
68 INT218846 Ppp1r9a Regulation of Ltp 1 0.15 2.24 1.07 43.76
69 INT218837 Ppp1cc Regulation of Ltp 1 0.13 1.19 0.62 43.76
70 INT218833 Binding of Ppp1cc and Regulation of Ltp 1 0.13 1.2 0.62 43.76
71 INT250054 Positive_regulation of Binding of Gpr143 and Spdya 1 0.04 0.52 0.59 43.52
72 INT250053 Binding of Gpr143 and Spdya 1 0.03 0.51 0.59 43.52
73 INT257304 Pde5a Positive_regulation of Oprd1 1 0.15 0.48 0.89 42.56
74 INT296324 NFE2L2 Regulation of GSTK1 1 0.01 0.91 0.14 42.48
75 INT284786 Trpv1 Positive_regulation of Gene_expression of Trpa1 1 0.45 0.36 0.07 39.52
76 INT101813 KEAP1 Negative_regulation of NFE2L2 3 0.47 1.63 0.28 36.96
77 INT284855 Binding of S100a10 and Nav1 4 0.21 0.99 0.88 35.36
78 INT101810 Binding of NFE2L2 and KEAP1 7 0.53 4.12 0.29 34.64
79 INT114811 Kcna7 Regulation of KCNQ2 1 0.00 0.69 0.13 34.32
80 INT114810 KCNQ3 Regulation of KCNQ2 1 0.05 0.35 0.06 33.92
81 INT251150 Binding of Nos1 and Dlg2 1 0.30 1.98 2.62 32.32
82 INT224823 CTBS Regulation of SALL1 1 0.14 0.53 0.66 32.12
83 INT127128 Binding of CNR1 and CNR2 8 0.39 3.98 3.97 29.40
84 INT284785 Gch1 Regulation of Bh4p 1 0.00 1.48 1.54 28.08
85 INT186160 Negative_regulation of Grin2b Negative_regulation of Grin1 1 0.37 0.5 0.72 25.72
86 INT149791 Binding of Lrp8 and Reln 4 0.36 0.38 0.22 25.00
87 INT149792 Binding of Reln and Vldlr 3 0.51 0.35 0.11 25.00
88 INT149794 Binding of LRP8 and Vldlr 1 0.02 0.17 0.04 25.00
89 INT149793 Binding of LRP8 and Reln 1 0.03 0.17 0.04 25.00
90 INT89432 Binding of LAMB2 and IGSF11 1 0.01 0.47 0 25.00
91 INT89431 Binding of LAMB2 and BCAM 1 0.05 0.47 0 25.00
92 INT219279 Ctss Positive_regulation of Gene_expression of Fam64a 1 0.06 1.39 0.96 24.28
93 INT219273 Fam64a Positive_regulation of Gene_expression of Ctss 1 0.06 1.39 0.96 24.28
94 INT172512 Mir343 Regulation of ECT 1 0.03 0.08 0.45 23.92
95 INT313377 Trib3 Regulation of Gene_expression of Gfap 1 0.01 0.37 0.44 23.84
96 INT313378 Trib3 Regulation of Phosphorylation of Mapk14 1 0.01 0.37 0.44 23.84
97 INT298288 Negative_regulation of Runx3 Positive_regulation of Negative_regulation of Ntrk3 1 0.35 0.27 0.17 19.48
98 INT277192 SUGT1 Positive_regulation of Gene_expression of SLC6A4 1 0.01 0.86 1.04 17.88
99 INT298292 Runx3 Positive_regulation of Gene_expression of Ntrk3 1 0.35 1.36 1.09 13.84
100 INT298265 Runx3 Negative_regulation of Gene_expression of Ntrk2 1 0.61 0.25 0.17 13.84
101 INT220032 Nos1 Positive_regulation of Nos3 1 0.32 0.45 0.66 11.20
102 INT220035 Nos1 Positive_regulation of Nos2 1 0.29 0.45 0.66 10.48
103 INT298283 Pou4f1 Positive_regulation of Gene_expression of Runx1 1 0.50 1.4 1.48 7.40
104 INT262377 Binding of Comt and Fmod 1 0.06 1.47 1.29 7.40
105 INT298297 Pou4f1 Positive_regulation of Gene_expression of Ntrk2 1 0.50 0.36 0.24 7.40
106 INT172515 Mir343 Positive_regulation of Positive_regulation of ECT 1 0.03 0.09 0.42 7.08
107 INT106676 Binding of Trpv1 and Phax 18 0.34 4.19 12.36 5.00
108 INT206768 TP53 Positive_regulation of Ltp 2 0.01 5.83 10.21 5.00
109 INT84921 Binding of NGF and NTRK1 13 0.50 6.39 6.1 5.00
110 INT15984 Binding of Avp and Oxt 11 0.32 1.33 3.64 5.00
111 INT220062 Binding of NGF and TNFRSF1B 1 0.10 2.21 2.81 5.00
112 INT170367 Binding of Grin1 and Grin2a 5 0.23 1.72 2.79 5.00
113 INT220061 Binding of TRPV1 and TRPA1 1 0.15 1.7 2.69 5.00
114 INT251147 Binding of Grin2b and Dlg2 1 0.33 2.75 2.43 5.00
115 INT284860 Binding of Pdzd2 and Nav1 9 0.29 2.33 2.34 5.00
116 INT103548 Binding of TRPV1 and TRPV3 3 0.37 1.82 2.28 5.00
117 INT251145 Binding of Grin2a and Dlg2 1 0.31 2.3 2.11 5.00
118 INT331105 Vmn1r71 Negative_regulation of Mc1r 1 0.04 0.64 2.07 5.00
119 INT97208 Binding of Gabrg1 and Gabbr1 2 0.07 0.31 1.94 5.00
120 INT262558 Phax Positive_regulation of Trpv1 1 0.01 1.26 1.92 5.00
121 INT351281 AP1M2 Regulation of NCOR2 1 0.00 0.85 1.9 5.00
122 INT93293 Ngf Regulation of Trpv1 2 0.28 0.71 1.9 5.00
123 INT272616 Positive_regulation of Binding of Grin1 and Grin2a 2 0.30 1.36 1.8 5.00
124 INT236491 GCH1 Regulation of Pain1 1 0.01 0.89 1.65 5.00
125 INT220058 NGF Positive_regulation of Gene_expression of BDNF 1 0.12 1.31 1.48 5.00
126 INT220059 NGF Positive_regulation of Positive_regulation of BDNF 1 0.11 1.31 1.48 5.00
127 INT121226 Ngf Regulation of Gene_expression of Trpv1 2 0.62 0.7 1.44 5.00
128 INT220060 Negative_regulation of Binding of NGF and NTRK1 1 0.08 1.11 1.39 5.00
129 INT262568 Prkaca Regulation of Trpv1 2 0.10 0.65 1.38 5.00
130 INT106850 P2ry2 Positive_regulation of Phosphorylation of Creb1 2 0.49 0.73 1.36 5.00
131 INT251142 Binding of Dlg4 and Grin2a 3 0.30 0.5 1.24 5.00
132 INT298260 Binding of Runx3 and Pou4f1 1 0.52 2.08 1.22 5.00
133 INT261410 Slc7a2 Positive_regulation of Ltp 1 0.06 0.08 1.21 5.00
134 INT204558 Tens1 Negative_regulation of Pdgfc 1 0.01 0.25 1.2 5.00
135 INT228681 Fkbp4 Negative_regulation of Trib3 1 0.00 0.57 1.2 5.00
136 INT228680 Fkbp1a Negative_regulation of Trib3 1 0.01 0.56 1.18 5.00
137 INT206766 Positive_regulation of Ltp Positive_regulation of Positive_regulation of Nkx1-1 1 0.01 0.22 1.16 5.00
138 INT326665 Cpe Positive_regulation of Oprd1 1 0.01 1.24 1.15 5.00
139 INT229913 Positive_regulation of Ntsr1 Positive_regulation of Gene_expression of Egr1 1 0.12 1.33 1.11 5.00
140 INT298272 Runx1 Positive_regulation of Gene_expression of Ntrk3 1 0.52 0.88 1.09 5.00
141 INT283934 Phax Negative_regulation of Positive_regulation of Mapk14 1 0.03 2.06 1.09 5.00
142 INT172508 Binding of Cnnm1 and Mir343 1 0.01 0.15 1.08 5.00
143 INT218840 Cysltr1 Positive_regulation of Ltp 2 0.02 1.04 1.06 5.00
144 INT331108 Mc1r Positive_regulation of Mc4r 1 0.44 1.05 1.06 5.00
145 INT331107 Vmn1r71 Positive_regulation of Mc1r 1 0.05 0.5 1.05 5.00
146 INT231391 Binding of Lpar1 and Rbm39 1 0.00 1.04 1.04 5.00
147 INT346835 Gene_expression of Efnb2 Positive_regulation of Phosphorylation of Grin2b 1 0.27 1.07 1.03 5.00
148 INT229914 Egr1 Positive_regulation of Phosphorylation of Mapk3 1 0.46 1.03 1.02 5.00
149 INT298298 Calca Negative_regulation of Gene_expression of Runx1 1 0.19 0.33 1 5.00
150 INT298274 Gene_expression of Runx1 Negative_regulation of Calca 1 0.19 0.33 1 5.00
151 INT283932 Positive_regulation of Mapk14 Regulation of Gene_expression of Trpv1 1 0.14 1.28 0.99 5.00
152 INT351311 Has1 Regulation of Gene_expression of MMP3 1 0.11 1.15 0.95 5.00
153 INT331109 Tpnr1 Regulation of Gene_expression of Calca 1 0.06 0.97 0.94 5.00
154 INT231392 Enpp2 Positive_regulation of Gene_expression of Lpar1 2 0.38 2.19 0.93 5.00
155 INT220031 Casp3 Positive_regulation of Gene_expression of Nos3 1 0.04 0 0.92 5.00
156 INT251153 Dlg2 Positive_regulation of Gene_expression of Grin2a 1 0.40 0.6 0.92 5.00
157 INT251152 Dlg2 Positive_regulation of Localization of Grin2b 1 0.43 0.6 0.92 5.00
158 INT326663 Bdnf Regulation of Positive_regulation of Arc 1 0.16 1.46 0.88 5.00
159 INT298289 Runx1 Negative_regulation of Ntrk2 1 0.60 1.09 0.87 5.00
160 INT326664 Bdnf Positive_regulation of Arc 1 0.27 1.07 0.86 5.00
161 INT326661 Bdnf Positive_regulation of Gene_expression of Arc 1 0.27 1.96 0.86 5.00
162 INT298295 Runx1 Negative_regulation of Gene_expression of Ntrk1 2 0.38 0.45 0.86 5.00
163 INT270218 P2rx3 Positive_regulation of Pla2g4a 1 0.34 0.63 0.85 5.00
164 INT262572 Ngf Positive_regulation of Mapk1 2 0.04 0.52 0.81 5.00
165 INT270217 Binding of C2 and Ca2 1 0.03 1.63 0.81 5.00
166 INT262564 Ngf Positive_regulation of Pik3r1 1 0.08 0.36 0.8 5.00
167 INT262579 Ngf Positive_regulation of Prkca 1 0.07 0.36 0.8 5.00
168 INT245564 Runx3 Negative_regulation of Ntrk2 3 0.61 1.61 0.79 5.00
169 INT220056 Binding of NTF3 and NTRK1 1 0.07 1.12 0.78 5.00
170 INT262582 F2rl1 Regulation of Positive_regulation of Prkca 1 0.03 0.58 0.78 5.00
171 INT220063 Binding of NTF3 and NTRK2 1 0.09 1.13 0.78 5.00
172 INT262562 F2rl1 Regulation of Trpv1 1 0.12 0.58 0.77 5.00
173 INT231390 Pla2g4a Regulation of Pla2g2a 1 0.08 0.92 0.77 5.00
174 INT231388 Pla2g4a Regulation of Pla2g6 1 0.08 0.92 0.77 5.00
175 INT220057 Binding of NTS and TNFRSF1B 1 0.08 1.23 0.76 5.00
176 INT262563 Negative_regulation of Pax3 Regulation of Calca 1 0.01 0.75 0.76 5.00
177 INT262569 Pax3 Regulation of Calca 1 0.00 0.75 0.76 5.00
178 INT262577 Localization of Ngf Positive_regulation of Positive_regulation of Mapk14 1 0.05 0.92 0.75 5.00
179 INT262578 Prkaca Positive_regulation of Localization of Calca 1 0.03 0.71 0.75 5.00
180 INT252858 C5 Negative_regulation of Positive_regulation of Trpa1 1 0.02 0.78 0.74 5.00
181 INT220033 Casp3 Positive_regulation of Gene_expression of Nos1 1 0.05 0.52 0.72 5.00
182 INT262573 Par2 Regulation of Positive_regulation of Prkca 1 0.05 0.57 0.72 5.00
183 INT262580 Ngf Positive_regulation of Hspg2 1 0.03 0.35 0.72 5.00
184 INT216654 Binding of P2ry2 and DRGX 1 0.01 1.59 0.71 5.00
185 INT262574 Gnaq Positive_regulation of Prkca 1 0.00 0.57 0.71 5.00
186 INT262566 Par2 Regulation of Trpv1 1 0.20 0.57 0.71 5.00
187 INT262571 Phosphorylation of Trpv1 Positive_regulation of Localization of Calca 1 0.17 0.71 0.7 5.00
188 INT186162 Phosphorylation of Prkaca Positive_regulation of Phosphorylation of Prkcg 1 0.04 0.22 0.7 5.00
189 INT262570 Binding of Pax3 and Trpv1 1 0.02 1.05 0.67 5.00
190 INT211915 Fig4 Positive_regulation of Mapk3 1 0.12 0.25 0.66 5.00
191 INT262576 Binding of Calca and Trpv1 1 0.13 1.05 0.66 5.00
192 INT211916 Fig4 Positive_regulation of Mapk1 1 0.13 0.25 0.66 5.00
193 INT216644 Binding of P2ry1 and P2ry2 1 0.24 0.55 0.64 5.00
194 INT219277 Mapkapk2 Positive_regulation of Pla2g1b 1 0.03 0.46 0.61 5.00
195 INT219278 Mapkapk2 Positive_regulation of Pla2g2a 1 0.05 0.46 0.61 5.00
196 INT219280 Mapk14 Positive_regulation of Pla2g2a 1 0.33 0.46 0.61 5.00
197 INT219282 Mapk14 Positive_regulation of Pla2g1b 1 0.18 0.46 0.61 5.00
198 INT218845 Ppp1cc Positive_regulation of Positive_regulation of Cysltr1 1 0.02 0.92 0.6 5.00
199 INT252869 Binding of Trpv1 and Phax 2 0.01 0.18 0.6 5.00
200 INT172511 Mir343 Positive_regulation of ECT 1 0.04 0.08 0.6 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Acute pain. They are ordered first by their pain relevance and then by number of times they were reported in Acute pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT17848 Binding of PTGS2 70 0.46 32.1 20.6 100.00
2 INT8210 Positive_regulation of Gene_expression of INS 188 0.68 146.57 12.83 99.98
3 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02 99.96
4 INT143663 Negative_regulation of Gene_expression of Gad2 2 0.43 2.32 2.75 99.96
5 INT83602 Positive_regulation of Gene_expression of TRPV1 114 0.70 51.19 56.35 99.90
6 INT9381 Positive_regulation of TRPV1 523 0.70 187.4 276.05 99.90
7 INT94450 Gene_expression of Nav1 359 0.78 131.85 275.46 99.84
8 INT45303 Binding of SYNM 4 0.40 2.14 3.07 99.84
9 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 99.82
10 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85 99.80
11 INT720 Positive_regulation of POMC 807 0.70 237.37 353.83 99.76
12 INT64159 Gene_expression of Prkca 90 0.78 34.65 55.97 99.76
13 INT3118 Negative_regulation of Positive_regulation of POMC 33 0.59 9.42 18.07 99.76
14 INT21833 Positive_regulation of C1QL1 4 0.67 3.39 2.15 99.76
15 INT58776 Negative_regulation of Positive_regulation of C1QL1 1 0.41 0.3 1.1 99.76
16 INT462 Regulation of Pomc 157 0.62 41.67 67.27 99.72
17 INT5202 Positive_regulation of Gene_expression of Fos 1163 0.70 319.28 684 99.66
18 INT18357 Gene_expression of TRPV1 825 0.78 307.11 382.81 99.62
19 INT11685 Regulation of CSF2 99 0.59 58.82 15.9 99.62
20 INT154697 Negative_regulation of Fpr2l 3 0.31 2.62 2.43 99.60
21 INT11764 Positive_regulation of ENG 78 0.61 27.65 33.69 99.56
22 INT21793 Positive_regulation of Ngf 154 0.70 94.78 85.27 99.56
23 INT22071 Positive_regulation of Gene_expression of ENG 13 0.50 5.44 2.62 99.56
24 INT48075 Positive_regulation of Il1b 71 0.67 48.63 40.48 99.56
25 INT8248 Binding of Adra2a 43 0.48 6.72 22.17 99.48
26 INT47845 Regulation of Localization of Prkcg 16 0.62 3.1 9.42 99.48
27 INT35975 Regulation of Cpox 109 0.39 57.88 49.69 99.42
28 INT7675 Gene_expression of ENG 146 0.77 45.35 34.6 99.36
29 INT4941 Positive_regulation of Oprd1 345 0.70 74.26 304.41 99.28
30 INT49750 Negative_regulation of CPOX 735 0.58 360.06 274.19 99.24
31 INT71565 Negative_regulation of Prkcc 11 0.54 4.16 9.31 99.24
32 INT27018 Gene_expression of PTGER1 68 0.75 31.76 20.12 99.20
33 INT12536 Localization of Prkcg 101 0.80 36.37 73.81 99.20
34 INT144051 Positive_regulation of Gene_expression of PTGER1 11 0.12 4.46 3.97 99.20
35 INT5539 Negative_regulation of Mme 75 0.59 28.91 41.84 99.12
36 INT64484 Binding of PNOC 12 0.33 5.51 10.86 99.08
37 INT52194 Positive_regulation of Grin1 83 0.69 25.09 34.76 99.08
38 INT117601 Positive_regulation of Trpa1 174 0.70 72.41 71.9 99.04
39 INT19775 Localization of Il1 183 0.78 145.5 50.91 99.04
40 INT25609 Localization of Il1f5 17 0.80 10.66 6.71 99.04
41 INT92518 Gene_expression of Grin2b 131 0.78 65.52 80.91 99.00
42 INT93451 Positive_regulation of Gene_expression of Grin2b 43 0.70 29.09 31.89 99.00
43 INT80006 Regulation of Gene_expression of Grin2b 8 0.57 3.75 9.62 99.00
44 INT148389 Regulation of Localization of Csda 1 0.26 0.63 0.52 98.96
45 INT148388 Localization of Csda 1 0.47 0.63 0.52 98.96
46 INT25363 Negative_regulation of Trpv1 144 0.59 64.78 75.7 98.90
47 INT127329 Negative_regulation of Tbpl1 2 0.41 0.51 0.6 98.90
48 INT100418 Negative_regulation of Bco2 3 0.42 1.19 1.27 98.84
49 INT48766 Regulation of NOS1 73 0.61 37.01 24.59 98.80
50 INT121872 Gene_expression of Camk4 156 0.78 70.47 21.39 98.76
51 INT87687 Positive_regulation of Trpv1 409 0.70 210.24 257.59 98.68
52 INT103172 Gene_expression of Slc12a5 81 0.77 39.45 36.22 98.56
53 INT100115 Gene_expression of Slc12a2 34 0.76 39.15 15.69 98.56
54 INT51922 Localization of Cpox 24 0.68 12.05 8.59 98.56
55 INT138891 Regulation of Gene_expression of Slc12a2 5 0.58 4.83 2.64 98.56
56 INT50058 Negative_regulation of Cpox 907 0.58 426.28 428.29 98.52
57 INT2649 Regulation of Calca 433 0.62 146.05 330.95 98.52
58 INT112099 Negative_regulation of Dlg2 2 0.40 6.17 8.16 98.52
59 INT16814 Negative_regulation of COX5A 74 0.57 33.72 28.63 98.44
60 INT23178 Gene_expression of H1 38 0.68 13.37 9.09 98.44
61 INT110521 Regulation of Crygb 5 0.28 1.42 2.92 98.44
62 INT49001 Regulation of Gria1 51 0.56 18.28 31.22 98.40
63 INT101744 Positive_regulation of COX1 4 0.67 1.16 1.83 98.32
64 INT82254 Positive_regulation of Gene_expression of Cxcl1 17 0.69 9.95 6.47 98.32
65 INT165668 Negative_regulation of Slc6a5 2 0.48 1.59 2.21 98.32
66 INT14624 Gene_expression of Pax3 100 0.38 33.22 69.47 98.28
67 INT120446 Positive_regulation of Cnr2 32 0.70 16.3 18.91 98.24
68 INT69764 Positive_regulation of Cnr1 126 0.70 67.8 91.49 98.24
69 INT1456 Regulation of Oprl1 61 0.62 19.5 52.87 98.24
70 INT6943 Positive_regulation of Gabrd 71 0.70 17.36 35.25 98.24
71 INT76621 Positive_regulation of Cnr2 32 0.69 17.77 26.57 98.24
72 INT8048 Gene_expression of Nts 45 0.74 8.9 21.84 98.16
73 INT93037 Regulation of Grin2b 26 0.57 11.9 16.92 98.12
74 INT79506 Gene_expression of Grin2b 122 0.78 43.71 73.42 98.12
75 INT138889 Positive_regulation of Slc12a2 23 0.65 18.53 8.85 98.12
76 INT138890 Regulation of Slc12a5 12 0.45 11.61 7.46 98.12
77 INT94356 Regulation of Slc12a2 11 0.58 12.8 6.59 98.12
78 INT103171 Positive_regulation of Slc12a5 15 0.51 3.6 6.25 98.12
79 INT127499 Positive_regulation of TRPA1 72 0.70 21.7 26.86 98.08
80 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84 98.08
81 INT316829 Negative_regulation of SYNM 4 0.54 3.31 3.32 98.04
82 INT6580 Negative_regulation of Ptgs1 929 0.59 381.53 376.26 98.00
83 INT86789 Gene_expression of P2rx4 46 0.77 30.66 25.68 98.00
84 INT112428 Positive_regulation of Gene_expression of P2rx4 12 0.68 12.67 9.57 98.00
85 INT27096 Positive_regulation of Nfkb1 325 0.70 195.11 109.06 97.96
86 INT59665 Positive_regulation of Ugt1a6 24 0.69 7.24 13.25 97.96
87 INT124051 Regulation of ACACA 4 0.60 1.1 1.98 97.96
88 INT8357 Gene_expression of KNG1 153 0.75 77.26 68.66 97.92
89 INT50674 Gene_expression of PTGS2 459 0.78 253.33 118.51 97.90
90 INT102370 Positive_regulation of Grm2 10 0.45 5.03 10.9 97.90
91 INT50490 Regulation of PTGS2 80 0.48 39.51 25.85 97.90
92 INT131413 Positive_regulation of Gene_expression of NAV1 35 0.70 17.5 36.83 97.84
93 INT52980 Positive_regulation of Dlat 20 0.37 5.14 4.06 97.64
94 INT143767 Negative_regulation of Trpm8 26 0.58 12.34 10.83 97.60
95 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 97.52
96 INT46460 Gene_expression of NAV1 288 0.78 135.51 305.75 97.44
97 INT7674 Regulation of ENG 42 0.30 11.41 14.44 97.44
98 INT12602 Negative_regulation of Oprm1 190 0.59 36.11 177.85 97.40
99 INT2490 Regulation of Sct 44 0.62 9.45 13.11 97.40
100 INT83886 Negative_regulation of HMOX2 27 0.43 11.69 10.78 97.36
101 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 97.32
102 INT82878 Gene_expression of Ccl2 201 0.78 164.95 101.35 97.32
103 INT614 Gene_expression of Cxcl2 29 0.76 25.53 20.8 97.32
104 INT158161 Gene_expression of GFRA2 1 0.00 2.23 1.77 97.32
105 INT66026 Gene_expression of Cxcl1 74 0.78 31.87 23.37 97.32
106 INT134798 Gene_expression of ANXA1 15 0.75 13.94 2.99 97.32
107 INT122682 Gene_expression of Galr2 11 0.63 5.06 10.77 97.28
108 INT159405 Negative_regulation of Transcription of Hmox2 1 0.02 0.55 0.62 97.28
109 INT159404 Transcription of Hmox2 1 0.04 0.55 0.62 97.28
110 INT51921 Gene_expression of Cpox 501 0.73 229.81 157.81 97.26
111 INT107329 Gene_expression of Me3 2 0.19 1.42 4.91 97.24
112 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 97.24
113 INT24962 Positive_regulation of Qrfp 16 0.50 5.81 13.92 97.24
114 INT73010 Gene_expression of Tmem132a 8 0.77 4.38 8.86 97.24
115 INT95646 Negative_regulation of Faah 63 0.59 25.61 36.78 97.16
116 INT5298 Negative_regulation of MTHFS 70 0.57 27.07 28.11 97.08
117 INT108814 Regulation of Gene_expression of PTGES 8 0.59 3.62 3.54 96.88
118 INT69992 Negative_regulation of Hmox2 93 0.50 49.01 44.07 96.84
119 INT64436 Gene_expression of P2rx1 93 0.78 32.69 36.12 96.84
120 INT69991 Negative_regulation of Gene_expression of Hmox2 3 0.04 2.05 2.51 96.84
121 INT224827 Regulation of SALL1 2 0.37 3.36 0.62 96.80
122 INT250050 Gene_expression of Gpr143 1 0.48 5.76 6.53 96.72
123 INT11441 Negative_regulation of Anpep 18 0.59 3.73 7.51 96.68
124 INT35097 Gene_expression of Cux1 6 0.58 3.86 12.83 96.64
125 INT89925 Gene_expression of NR1I2 22 0.75 9.63 4.21 96.60
126 INT110020 Gene_expression of Mapk14 142 0.77 72.33 30.08 96.56
127 INT1033 Positive_regulation of Ca2 507 0.68 131.76 147.64 96.56
128 INT110024 Negative_regulation of Gene_expression of Mapk14 19 0.42 7.83 4.21 96.56
129 INT1307 Positive_regulation of Localization of Pomc 120 0.70 24.58 58.48 96.54
130 INT51320 Regulation of Localization of Pag1 4 0.17 3.34 6.15 96.52
131 INT1308 Localization of Pomc 457 0.81 66.83 217.5 96.40
132 INT3359 Regulation of YY1 32 0.60 8.19 19.2 96.40
133 INT82461 Gene_expression of Gad2 40 0.78 19.12 22.79 96.36
134 INT130280 Positive_regulation of Gene_expression of Gad2 7 0.69 8.13 9.55 96.36
135 INT63419 Gene_expression of PTGES 109 0.77 40.83 23.67 96.32
136 INT8650 Gene_expression of Gal 152 0.78 61.97 81.72 96.32
137 INT61706 Regulation of Gene_expression of Gal 17 0.62 10.09 11.96 96.32
138 INT5040 Regulation of Gal 42 0.60 12.72 21.18 96.32
139 INT1282 Negative_regulation of Dao 4 0.59 3.08 3.2 96.20
140 INT69743 Gene_expression of Hmox2 36 0.78 20.77 14.26 96.12
141 INT8465 Regulation of Ptgs1 100 0.57 36.03 44.41 96.08
142 INT31528 Regulation of TYR 6 0.44 0.83 3.63 96.00
143 INT112430 Negative_regulation of P2rx4 9 0.57 8.4 6.63 95.88
144 INT63852 Gene_expression of Gphn 21 0.63 5.64 8.2 95.84
145 INT61873 Gene_expression of Arc 128 0.78 128.25 52.24 95.76
146 INT9304 Negative_regulation of Pag1 70 0.39 51.97 64.23 95.68
147 INT282317 Negative_regulation of Gene_expression of Arc 4 0.37 6.87 1.68 95.64
148 INT55335 Binding of Cpox 49 0.34 15.48 18.46 95.60
149 INT105021 Binding of GOPC 187 0.40 60.39 20.38 95.58
150 INT4742 Gene_expression of Tac1 177 0.78 69.99 102.66 95.52
151 INT110023 Negative_regulation of Mapk14 127 0.59 84.27 45.42 95.52
152 INT67975 Gene_expression of Bdkrb2 38 0.68 21.69 17.94 95.52
153 INT2391 Negative_regulation of PTGS1 501 0.59 207.62 205.6 95.36
154 INT152580 Regulation of Gene_expression of Galr2 1 0.50 2.65 4.63 95.32
155 INT55944 Positive_regulation of Cpox 214 0.57 105.14 81.4 95.32
156 INT5759 Positive_regulation of Ptgs1 127 0.69 53.45 53.04 95.32
157 INT155988 Regulation of Localization of ABAT 5 0.24 2.19 6.59 95.28
158 INT134016 Transcription of DRGX 3 0.25 3.82 3 95.28
159 INT216648 Transcription of P2ry6 2 0.33 1.27 0.88 95.28
160 INT165934 Negative_regulation of Bambi 1 0.32 0.51 0.67 95.28
161 INT277579 Binding of Hdac4 1 0.37 3.84 0.38 95.20
162 INT11340 Positive_regulation of SLC17A5 120 0.67 113.52 14.5 95.16
163 INT57192 Binding of Ltp 43 0.41 17.48 24.96 95.08
164 INT112427 Positive_regulation of P2rx4 27 0.68 26.29 21.31 95.04
165 INT9298 Positive_regulation of Gtpbp4 64 0.69 12.29 41.97 95.04
166 INT103723 Regulation of Positive_regulation of Gtpbp4 5 0.22 1.56 6.35 95.04
167 INT49631 Gene_expression of Slc43a3 14 0.59 4.15 2.15 95.00
168 INT120873 Gene_expression of Fhl1 3 0.08 0.45 1.9 94.92
169 INT19768 Negative_regulation of LAMC2 11 0.57 10.54 5.32 94.92
170 INT109430 Positive_regulation of Trpa1 119 0.70 44 49.14 94.84
171 INT86698 Gene_expression of Cav1 38 0.78 16.37 11.75 94.56
172 INT216511 Negative_regulation of Gene_expression of P2RX2 1 0.03 1.74 1.54 94.56
173 INT89045 Negative_regulation of P2RX2 4 0.41 2.75 2.88 94.56
174 INT76620 Gene_expression of Cnr2 93 0.78 34.7 50.14 94.52
175 INT74376 Gene_expression of Cnr1 173 0.78 73.43 89.7 94.52
176 INT12175 Positive_regulation of PDYN 86 0.69 18.27 62.04 94.52
177 INT49473 Gene_expression of MSR1 14 0.75 7.28 2.64 94.52
178 INT117982 Gene_expression of Stresp2 2 0.72 0.83 1.61 94.52
179 INT117983 Gene_expression of Stresp1 1 0.55 0.52 1.47 94.52
180 INT44545 Gene_expression of Dclk2 5 0.65 0.77 1.41 94.20
181 INT21463 Binding of Epha1 5 0.46 1.44 3.25 94.20
182 INT876 Localization of Gh1 843 0.80 67.75 340.82 94.08
183 INT158 Localization of Prl 2431 0.81 378.96 952.2 94.08
184 INT10799 Localization of ENG 63 0.78 18.67 27.28 94.08
185 INT7800 Localization of Pag1 51 0.56 33.06 53.74 94.04
186 INT5379 Gene_expression of Fos 656 0.78 255.5 292.54 93.84
187 INT5380 Positive_regulation of Gene_expression of Fos 243 0.70 105.65 131.05 93.84
188 INT7059 Regulation of Adra2a 89 0.62 18.24 48.43 93.76
189 INT34106 Negative_regulation of Htr1a 14 0.57 4.72 8.73 93.68
190 INT96924 Positive_regulation of Hspg2 40 0.49 14.5 12.32 93.64
191 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 93.56
192 INT19488 Localization of ABAT 56 0.69 21.51 50.56 93.52
193 INT1438 Localization of Pomc 360 0.81 101.26 116.47 93.40
194 INT48883 Negative_regulation of GRIN3B 19 0.54 14.53 11.5 93.40
195 INT93033 Negative_regulation of Grin2b 48 0.58 20.94 28.54 93.36
196 INT15898 Positive_regulation of Prkaca 199 0.70 50.89 87.54 93.32
197 INT3002 Binding of SUGT1 62 0.24 55.9 14.91 93.24
198 INT106719 Gene_expression of Adcy1 18 0.77 12.18 8.42 93.20
199 INT106721 Regulation of Adcy1 6 0.45 2.32 4.17 93.20
200 INT4830 Binding of Trpv1 158 0.48 45.11 84.2 93.12
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