P:Antinociceptive

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pChart

Pain Term
Category Drug class
Synonyms Anti Nociceptive
Pain Specific No
Documents 7129
Hot Single Events 200
Hot Interactions 200

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Antinociceptive. They are ordered first by their pain relevance and then by number of times they were reported for Antinociceptive. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT87222 Nrg1 Regulation of Oprd1 1 0.00 0 1.07 100.00
2 INT30146 Binding of Adarb1 and Pdyn 1 0.01 0.17 1.91 100.00
3 INT64540 Binding of Pag1 and Rvm 1 0.04 0.61 0.61 100.00
4 INT127099 Memo1 Negative_regulation of Nfkb1 1 0.11 0.57 0.36 100.00
5 INT127100 Memo1 Negative_regulation of Binding of Nfkb1 1 0.11 0.57 0.36 100.00
6 INT137699 AR Regulation of PDYN 1 0.46 0.93 0.75 100.00
7 INT55641 Binding of CHRM1 and Adra2a 1 0.00 0 0.24 100.00
8 INT66129 Binding of Tia1 and Olfr927-ps1 1 0.16 0.16 0.56 100.00
9 INT165450 Gal Regulation of Ceacam3 1 0.41 0.06 1.47 100.00
10 INT26222 Calca Positive_regulation of Calca Regulation of Gt(pU21)50Imeg 1 0.01 0 2.02 100.00
11 INT26221 Calca Regulation of Gt(pU21)50Imeg 1 0.01 0 2.02 100.00
12 INT83903 Penk Positive_regulation of Npff 1 0.49 0 1.02 100.00
13 INT109380 Binding of Adarb1 and Fos 1 0.02 0.38 1.19 100.00
14 INT119130 Binding of Nos2 and Ptgs2 1 0.33 0.07 0.17 99.98
15 INT156608 Trpv1 Regulation of Nav1 1 0.51 0.52 0.95 99.98
16 INT172512 Mir343 Regulation of ECT 1 0.03 0.08 0.45 99.98
17 INT125301 Nts Positive_regulation of Unc5c 1 0.00 0 1.03 99.84
18 INT51705 Binding of Penk and Naga 1 0.19 0.08 0.69 99.78
19 INT37840 Binding of Cyp27b1 and Oprd1 1 0.01 0 1.73 99.76
20 INT150456 Binding of Sort1 and Nts 3 0.45 0.64 1.79 99.76
21 INT112218 Ntsr2 Positive_regulation of H2-Ab1 1 0.06 0 0.64 99.74
22 INT90046 Oprm1 Positive_regulation of P9Ehs1 2 0.16 0.92 1.63 99.72
23 INT90045 Oprd1 Positive_regulation of P9Ehs1 1 0.19 0.92 0.64 99.72
24 INT55639 Binding of Bche and Man2a2 1 0.02 0 0.45 99.62
25 INT126831 Binding of Oprk1 and Rbm39 1 0.05 0.88 1.33 99.60
26 INT147473 Nfe2l2 Positive_regulation of Gene_expression of Hmox1 1 0.74 0.49 0.39 99.52
27 INT315180 Gene_expression of Mors1 Positive_regulation of Gene_expression of Oprm1 1 0.03 0.48 1.64 99.48
28 INT315181 Gene_expression of Mors1 Positive_regulation of Oprm1 1 0.03 0.48 1.64 99.48
29 INT96496 Binding of Oprk1 and Cq1 1 0.01 0.27 0.64 99.44
30 INT27997 Oprd1 Positive_regulation of Localization of Me1 1 0.03 0 0.44 99.44
31 INT249565 Binding of Gabrg1 and Oprd1 1 0.00 0.1 1.33 99.32
32 INT274895 Positive_regulation of Cbr2 Negative_regulation of Gene_expression of TNF 1 0.06 1.21 0.99 99.32
33 INT22501 Binding of Calca and Pth 1 0.21 0.07 1.28 99.28
34 INT305335 Olfr927-ps1 Negative_regulation of Akr1b3 1 0.02 1.6 0.17 99.28
35 INT37839 Positive_regulation of Binding of Cyp27b1 and Oprd1 1 0.01 0 0.86 99.22
36 INT63384 Binding of Cnr1 and Insrr 1 0.03 0.24 1.2 99.12
37 INT29279 Binding of Drd1a and Htr1a 1 0.35 0.2 0.84 99.12
38 INT90929 Binding of Ap1m1 and Insrr 1 0.01 0.19 1.6 99.02
39 INT146826 Binding of Galr1 and Gtpbp4 1 0.03 0.17 0.22 98.86
40 INT147913 Phosphorylation of Camk2a Positive_regulation of Binding of Lpl 1 0.10 0 0.77 98.52
41 INT147474 Nfe2l2 Positive_regulation of Hmox1 1 0.43 0.38 0.9 98.48
42 INT107219 Binding of P2rx7 and Atp5o 1 0.03 0.07 0.21 98.48
43 INT107578 Kitl Negative_regulation of Grin2b 1 0.12 2.05 2.36 98.44
44 INT107579 Kitl Negative_regulation of Grin2a 1 0.10 1.02 1.18 98.44
45 INT352201 Negative_regulation of ALOX5 Negative_regulation of Cpox 1 0.02 0.89 0.81 98.30
46 INT172515 Mir343 Positive_regulation of Positive_regulation of ECT 1 0.03 0.09 0.42 98.28
47 INT149844 Negative_regulation of Cxcl12 Negative_regulation of C19orf10 1 0.16 0.45 1.26 98.28
48 INT149845 Cxcl12 Negative_regulation of C19orf10 1 0.16 0.45 1.24 98.28
49 INT58678 Binding of Penk and Abat 2 0.40 1.39 1.97 98.24
50 INT107331 Binding of PPBP and Adarb1 1 0.01 0 3.67 98.20
51 INT107223 APEH Negative_regulation of P2rx7 1 0.00 0.13 0.21 97.96
52 INT147475 co Positive_regulation of Gene_expression of Nfe2l2 1 0.01 0.57 0.36 97.76
53 INT141907 F2r Regulation of Plat 1 0.46 0 1.59 97.72
54 INT63919 Binding of Cck and Insrr 1 0.01 0 2.08 97.56
55 INT63918 Binding of Cck and Ripk2 1 0.28 0 2.07 97.56
56 INT51497 Cck Negative_regulation of Localization of Trim13 1 0.34 0 4.53 97.52
57 INT150350 Oprk1 Regulation of Pat 1 0.22 0.38 0.81 97.52
58 INT150348 Oprd1 Regulation of Pat 1 0.01 0.38 0.81 97.52
59 INT147472 co Positive_regulation of Gene_expression of Hmox1 1 0.01 0.57 0.36 97.44
60 INT44312 Binding of Trh and Pag1 1 0.05 0.36 0.41 97.44
61 INT142527 Binding of Slc1a2 and Slc1a3 2 0.31 0.12 2.13 97.40
62 INT61164 Binding of Pomc and Pcyt1a 1 0.17 0.24 0.61 97.40
63 INT258170 Binding of Adora1 and Ppap2a 1 0.05 0.26 0.94 97.36
64 INT158711 Cdk5 Positive_regulation of Phosphorylation of Trh 1 0.02 0 1.46 97.32
65 INT352196 Igkv12-66 Negative_regulation of Gm10404 1 0.00 1.62 1.34 97.12
66 INT88080 Binding of Chrna4 and Psmb6 1 0.03 0.56 0.46 97.08
67 INT125300 Nts Positive_regulation of Ntsr1 1 0.04 0 0.99 96.64
68 INT257304 Pde5a Positive_regulation of Oprd1 1 0.15 0.48 0.89 96.44
69 INT144299 Il1b Positive_regulation of Oprm1 1 0.42 0.4 0.74 96.28
70 INT348403 FDPS Negative_regulation of FDPS Negative_regulation of Fdps 1 0.03 0.79 0.71 96.24
71 INT46645 Binding of Gabrg1 and Chrm5 1 0.29 0.09 1 96.00
72 INT139736 Htr1a Positive_regulation of Mapk3 1 0.54 0.13 1.19 95.96
73 INT159837 Trim2 Negative_regulation of Transcription of Fos 1 0.10 1.92 1.22 95.80
74 INT142225 Urb1 Positive_regulation of Trpa1 1 0.04 0.59 0.71 95.68
75 INT142230 Urb1 Positive_regulation of Gene_expression of Trpa1 1 0.04 0.4 0.5 95.68
76 INT151485 Negative_regulation of Binding of Ptpn6 and Oprd1 1 0.00 0 0.47 95.68
77 INT151483 Negative_regulation of Binding of Oprd1 and Penk 1 0.02 0 0.47 95.68
78 INT172511 Mir343 Positive_regulation of ECT 1 0.04 0.08 0.6 95.64
79 INT46246 Tpsg1 Regulation of Ache 1 0.15 0.06 0.76 95.60
80 INT46247 Tpsg1 Regulation of Binding of Ache 1 0.15 0.06 0.76 95.60
81 INT24967 Olr567 Regulation of Localization of Syt17 1 0.11 0.62 0.71 95.60
82 INT96296 Oprm1 Negative_regulation of Npr1 2 0.05 0.32 1.65 95.44
83 INT108438 Grin2b Regulation of Pdyn 1 0.16 0.25 0.9 95.40
84 INT130607 Hcrt Positive_regulation of H1 1 0.59 0.39 1.02 95.32
85 INT76508 Pnoc Regulation of Oprl1 1 0.47 0.25 1.32 95.28
86 INT106374 Olr833 Negative_regulation of Abcb1a 1 0.00 0 0.56 95.20
87 INT150680 Pomc Negative_regulation of Gene_expression of Eif2ak3 1 0.35 0.07 0.8 95.04
88 INT146352 Binding of Rgs14 and Mors1 1 0.23 0.27 1.17 94.88
89 INT21276 Binding of Oprd1 and Penk 9 0.54 1.14 8.28 94.76
90 INT60867 Binding of G2e3 and Gpm6a 2 0.01 0.1 1.93 94.76
91 INT151484 Binding of Ptpn6 and Oprd1 1 0.00 0 0.47 94.76
92 INT57509 Trh Negative_regulation of Adarb1 1 0.02 0.22 1.05 94.60
93 INT142490 Avp Regulation of Oxt 1 0.09 0.74 1.4 94.44
94 INT149185 Regulation of H2-Ab1 Regulation of Trpv1 1 0.34 0.52 0.08 94.32
95 INT84414 Folr2 Regulation of Binding of Oprd1 1 0.03 0.18 0.84 94.20
96 INT109374 Ppp1cc Negative_regulation of Ppp2r1a 1 0.24 0 1.11 94.08
97 INT168926 Binding of Om and Imraq2 1 0.01 0.07 0.91 94.08
98 INT168927 Positive_regulation of Binding of Om and Imraq2 1 0.02 0.07 0.91 94.08
99 INT258171 Binding of Asap1 and Adp 1 0.04 0 0.31 94.00
100 INT291578 Negative_regulation of Pde12 Positive_regulation of Pde5a 1 0.03 1.11 1.67 94.00
101 INT158809 Pag1 Regulation of Rvm 1 0.02 1.28 2.33 94.00
102 INT168925 Binding of Oprm1 and Imraq2 1 0.04 0.13 1.78 93.76
103 INT168924 Positive_regulation of Binding of Oprm1 and Imraq2 1 0.06 0.13 1.78 93.76
104 INT104320 Binding of Adk and Ado 1 0.33 0.3 1.12 93.64
105 INT138099 Binding of Grin2a and Insrr 1 0.01 0.36 1.39 93.40
106 INT80752 Binding of Il1b and El4 1 0.49 0.08 0.54 93.28
107 INT80751 Negative_regulation of Binding of Il1b and El4 1 0.60 0.08 0.54 93.28
108 INT90067 Binding of Oprd1 and Npff 1 0.20 0.09 0.52 93.28
109 INT149184 H2-Ab1 Regulation of Trpv1 1 0.34 0.52 0.08 93.16
110 INT57508 Pomc Negative_regulation of Adarb1 1 0.01 0.22 1.05 92.84
111 INT73710 Mastl Positive_regulation of Localization of Oprl1 1 0.02 0 1.26 92.64
112 INT118784 Thop1 Positive_regulation of Protein_catabolism of Pax3 1 0.07 0.07 1.25 92.64
113 INT158774 Mapk14 Regulation of Il6 1 0.11 0.08 1.57 92.56
114 INT143578 Olr404 Negative_regulation of Positive_regulation of Fos 1 0.01 0.39 0.93 92.44
115 INT92738 Binding of Ephb1 and Tcas1 1 0.00 0.43 2.67 92.16
116 INT311256 Nt5e Positive_regulation of Positive_regulation of Adora1 1 0.49 0.19 0.54 91.92
117 INT140015 Avp Positive_regulation of Localization of Penk 3 0.63 3.48 6.63 91.92
118 INT54199 Binding of Pag1 and Agp2 1 0.04 0.18 0.91 91.72
119 INT54198 Agp2 Negative_regulation of Pag1 1 0.05 0.18 0.91 91.72
120 INT54188 Agp2 Negative_regulation of Binding of Oprd1 and Pag1 1 0.00 0.18 0.91 91.72
121 INT54196 Binding of Oprd1 and Agp2 1 0.00 0.18 0.91 91.72
122 INT54202 Gnai1 Negative_regulation of Binding of Pag1 and Agp2 1 0.01 0.18 0.91 91.72
123 INT182706 NPFF Regulation of Binding of TP53INP2 1 0.01 0.07 1.52 91.68
124 INT203033 Cnr1 Regulation of Cnr2 1 0.15 0.29 0.56 91.64
125 INT87646 Dbi Regulation of Olfr1507 1 0.00 0.69 0.72 91.48
126 INT81769 Binding of Chrna4 and Neurod1 1 0.35 0.07 0.69 91.32
127 INT150596 Binding of Oprd1 and Oprk1 1 0.08 0.14 2.59 90.96
128 INT150595 Binding of Oprk1 and Insrr 1 0.01 0.07 1.23 90.96
129 INT114126 Binding of APLNR and OPRL1 1 0.01 0.47 2.85 90.84
130 INT322411 Hist1h1t Positive_regulation of Positive_regulation of OPRM1 1 0.00 1.25 3.63 90.84
131 INT147033 Positive_regulation of Binding of Sds and Accn3 1 0.13 0.73 1.23 90.80
132 INT147032 Binding of Sds and Accn3 1 0.09 0.73 1.22 90.80
133 INT137248 Slc6a14 Negative_regulation of Gene_expression of Ptgs2 1 0.19 1.32 0.58 90.76
134 INT137247 Slc6a14 Negative_regulation of Ptgs2 2 0.19 1.38 0.58 90.76
135 INT87513 Binding of Tac2 and Abat 1 0.09 0.26 0.78 90.60
136 INT35525 Cck Negative_regulation of Regulation of Pomc 1 0.37 0 0.09 90.60
137 INT105295 WAS Regulation of PTGS1 1 0.02 0.13 1.27 90.44
138 INT161082 asp3 Regulation of Gpt 1 0.23 0.67 0.4 90.24
139 INT21331 Binding of Adarb1 and Gm5195 1 0.00 0.26 1.08 90.08
140 INT21329 Binding of Man2a2 and Gm5195 1 0.00 0.26 1.06 90.08
141 INT21332 Binding of Drd2 and Gm5195 1 0.01 0.26 1 90.08
142 INT21330 Binding of Htr1f and Gm5195 1 0.00 0.26 0.99 90.08
143 INT166663 Mpzl2 Negative_regulation of Positive_regulation of Ptgs2 1 0.29 0.3 0.24 90.04
144 INT334526 Trpv1 Positive_regulation of Gene_expression of Sema3a 1 0.31 0.92 0.55 90.00
145 INT54200 Gnai1 Negative_regulation of Pag1 1 0.05 0.18 0.9 89.96
146 INT54197 Binding of Gnai1 and Pag1 1 0.04 0.18 0.9 89.96
147 INT54187 Gnai1 Negative_regulation of Binding of Oprd1 and Pag1 1 0.00 0.18 0.9 89.96
148 INT84434 Calca Negative_regulation of Negative_regulation of Hrh1 1 0.06 0.19 1.44 89.84
149 INT125857 Insrr Negative_regulation of Oprm1 1 0.01 0.27 1.24 89.84
150 INT141635 Binding of APOB and Alb 1 0.02 0.3 0.26 89.68
151 INT141634 Binding of Alb and Nrg1 1 0.00 0.3 0.26 89.68
152 INT135035 Binding of Hk1 and Tac1 1 0.35 0.18 2.14 89.44
153 INT158878 CRX Positive_regulation of Gene_expression of Fos 1 0.02 1.49 0.41 89.20
154 INT12052 Xcl1 Negative_regulation of Rnpep 1 0.01 0 0.71 88.96
155 INT161916 Binding of POMC and Oprd1 1 0.01 0 0.89 88.64
156 INT161917 Negative_regulation of Binding of POMC and Oprd1 1 0.01 0 0.89 88.64
157 INT150681 Pomc Positive_regulation of Camk2a 1 0.47 0.07 0.8 88.64
158 INT137246 Slc6a14 Negative_regulation of Gene_expression of Fos 1 0.10 1.24 0.54 88.56
159 INT161224 Ccl2 Positive_regulation of Ccr2 1 0.52 2.09 1.88 88.48
160 INT161225 Ccl2 Positive_regulation of Ccl2 Positive_regulation of Ccr2 1 0.57 2.09 1.88 88.48
161 INT54194 Binding of Oprd1 and Pag1 1 0.01 0.18 0.89 88.48
162 INT150455 Binding of Prss12 and Nts 3 0.24 1.42 2.66 88.20
163 INT150457 Binding of Sort1 and Prss12 3 0.21 1.36 2.64 88.20
164 INT82754 Cck Positive_regulation of Positive_regulation of Pomc 1 0.39 0.3 1.21 88.20
165 INT148821 Binding of Oprm1 and Grin1 1 0.05 0.24 1.55 88.16
166 INT158877 PRS Positive_regulation of Gene_expression of Fos 1 0.09 5.14 1.54 88.00
167 INT57263 Binding of Oprd1 and Atxn2l 1 0.02 0 1.29 87.76
168 INT57262 Binding of Gria4 and Oprd1 1 0.06 0 1.29 87.76
169 INT148820 Binding of Oprm1 and Naa15 1 0.02 0.24 1.55 87.76
170 INT112526 D2Mit212 Negative_regulation of Gene_expression of Fos 1 0.03 0.28 1.8 87.76
171 INT102316 Ugt1a6a Positive_regulation of Cyb5 1 0.16 0.08 0.64 87.68
172 INT107933 Oprm1 Positive_regulation of Gene_expression of Mastl 1 0.33 0.61 0.71 87.52
173 INT158778 Ptges3l1 Regulation of Ephb1 1 0.06 0.09 1.53 87.44
174 INT29240 Binding of POMC and YY1 5 0.40 0.17 4.06 87.36
175 INT172508 Binding of Cnnm1 and Mir343 1 0.01 0.15 1.08 87.36
176 INT161915 Negative_regulation of Binding of POMC and YY1 1 0.33 0 0.88 87.36
177 INT144115 Positive_regulation of Grm5 Positive_regulation of Prkcg 1 0.41 0 2.01 87.08
178 INT76237 Olr594 Positive_regulation of Gene_expression of Fos 1 0.05 0.09 0.59 86.64
179 INT88971 Binding of Sult4a1 and Atrn 1 0.02 0.54 1.03 86.28
180 INT18026 Binding of Oprd1 and Oprm1 4 0.40 0.83 3.53 85.52
181 INT77376 Tmie Negative_regulation of Mastl 1 0.01 0 0.59 85.52
182 INT77379 Tmie Negative_regulation of Ebp 1 0.03 0 0.59 85.52
183 INT77380 Tmie Negative_regulation of Fbln5 1 0.01 0 0.59 85.52
184 INT209087 Crh Positive_regulation of Ceacam3 1 0.24 1.45 1.54 85.28
185 INT143492 OPRL1 Regulation of PNOC 1 0.05 0 0.99 85.28
186 INT75247 Abat Regulation of Gene_expression of Tacr1 1 0.23 0.41 1.03 84.56
187 INT33802 Binding of Sct and ECT 1 0.07 0 0.28 84.24
188 INT333967 Binding of Osm and Sgp158 1 0.00 0.92 0.56 84.24
189 INT168866 Binding of RYR1 and Cd38 1 0.02 0.17 1.28 84.24
190 INT128310 Oprm1 Positive_regulation of Oprm1 1 0.00 0.1 1.29 84.12
191 INT158775 Regulation of Tnf Regulation of Ephb1 1 0.18 0.09 1.52 84.00
192 INT158777 Tnf Regulation of Ephb1 1 0.18 0.09 1.51 84.00
193 INT348398 LPA Positive_regulation of Pik3cb 1 0.04 0.88 1.14 83.56
194 INT348400 LPA Positive_regulation of Trib3 1 0.00 0.87 1.14 83.56
195 INT166664 Mpzl2 Negative_regulation of Mmp9 1 0.31 0.32 0.25 83.40
196 INT166662 Mpzl2 Negative_regulation of Positive_regulation of Mmp9 1 0.31 0.32 0.25 83.40
197 INT68298 Binding of Neurod1 and Abt1 1 0.24 0 0.26 83.36
198 INT91860 Npy Regulation of Npy1r 2 0.28 1.13 2.24 83.36
199 INT121218 Arrb2 Regulation of Negative_regulation of Prkca 1 0.17 0.23 1.8 83.28
200 INT61165 Binding of Pag1 and Pcyt1a 1 0.01 0.33 0.73 83.24

Single Events

The table below shows the top 200 pain related interactions that have been reported for Antinociceptive. They are ordered first by their pain relevance and then by number of times they were reported in Antinociceptive. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT1665 Positive_regulation of Pag1 270 0.68 186.63 229.87 100.00
2 INT6056 Negative_regulation of Gene_expression of Fos 601 0.59 193.05 386.84 100.00
3 INT4941 Positive_regulation of Oprd1 345 0.70 74.26 304.41 100.00
4 INT1351 Gene_expression of Pag1 131 0.57 89.48 98.76 100.00
5 INT5501 Regulation of Oprd1 283 0.62 55.1 249.9 100.00
6 INT292 Localization of Penk 876 0.81 88.44 669.14 100.00
7 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 100.00
8 INT728 Positive_regulation of Penk 1068 0.70 186.9 636.87 100.00
9 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08 100.00
10 INT943 Negative_regulation of Cck 205 0.59 38.42 174.78 100.00
11 INT2366 Binding of Cck 192 0.48 30.64 163.46 100.00
12 INT12865 Positive_regulation of U 7 0.50 5.13 5.29 100.00
13 INT69764 Positive_regulation of Cnr1 126 0.70 67.8 91.49 100.00
14 INT1395 Negative_regulation of Penk 537 0.59 87.33 389.81 100.00
15 INT18755 Positive_regulation of Rvm 79 0.60 60 92.93 100.00
16 INT29144 Gene_expression of Rvm 41 0.52 29.23 47.76 100.00
17 INT16603 Negative_regulation of Tead4 4 0.41 0.6 2.93 100.00
18 INT9694 Positive_regulation of Csf2 102 0.68 70.09 33.07 100.00
19 INT9304 Negative_regulation of Pag1 70 0.39 51.97 64.23 100.00
20 INT135673 Positive_regulation of Slc1a3 23 0.57 5.45 21.45 100.00
21 INT2649 Regulation of Calca 433 0.62 146.05 330.95 100.00
22 INT157580 Phosphorylation of Cdk5 4 0.77 0.73 8.33 100.00
23 INT105197 Negative_regulation of GTS 14 0.37 3.88 17.14 100.00
24 INT1652 Regulation of Pomc 387 0.62 61.01 186.51 100.00
25 INT99539 Positive_regulation of Slc1a2 25 0.67 5.46 23.38 100.00
26 INT66381 Regulation of Prkaca 40 0.62 13.38 27.96 100.00
27 INT2651 Positive_regulation of Pomc 403 0.70 95.72 206.24 100.00
28 INT15769 Gene_expression of Il1b 146 0.78 114.51 75.35 100.00
29 INT16654 Gene_expression of Insrr 138 0.46 58.96 75.68 100.00
30 INT1437 Negative_regulation of Pomc 132 0.59 35.22 60.97 100.00
31 INT8363 Localization of Nts 135 0.81 14.29 61.71 100.00
32 INT34465 Regulation of Oprd1 34 0.45 7.14 34.29 100.00
33 INT34263 Positive_regulation of Mastl 8 0.35 1.36 4.35 100.00
34 INT58062 Negative_regulation of Gene_expression of Trpv1 66 0.59 22.34 38.02 100.00
35 INT13610 Regulation of Acyp2-ps1 10 0.62 3.29 9.4 100.00
36 INT19689 Regulation of Tes 5 0.24 1.01 2.76 100.00
37 INT57692 Positive_regulation of Gene_expression of Il1b 50 0.67 43.54 28.29 100.00
38 INT149258 Negative_regulation of Negative_regulation of GTS 3 0.22 0.49 3.69 100.00
39 INT58774 Negative_regulation of G2e3 8 0.38 0.22 7.75 100.00
40 INT5675 Gene_expression of Adra2c 7 0.75 1.25 4.58 100.00
41 INT55434 Positive_regulation of Gene_expression of HSP90B2P 14 0.38 10.91 4.83 100.00
42 INT28857 Negative_regulation of Positive_regulation of Pag1 11 0.30 8.46 10.19 100.00
43 INT67274 Negative_regulation of Tes 2 0.38 0.09 0.82 100.00
44 INT16604 Regulation of Tead4 2 0.26 0.25 1.09 100.00
45 INT35910 Binding of Mme 8 0.37 4.79 3.16 100.00
46 INT90909 Negative_regulation of Gene_expression of NOS1 44 0.55 23.83 12.47 100.00
47 INT126101 Regulation of Map3k14 2 0.44 0.77 3.38 100.00
48 INT6339 Negative_regulation of Ptpn6 6 0.14 0.71 3.44 100.00
49 INT9954 Negative_regulation of Hrh1 16 0.52 13.04 11.76 100.00
50 INT12864 Negative_regulation of Positive_regulation of U 2 0.27 1.06 1.33 100.00
51 INT72642 Regulation of Morph4 1 0.12 0 0.67 100.00
52 INT124920 Positive_regulation of Negative_regulation of Slc1a2 4 0.58 0.06 4.69 100.00
53 INT135675 Positive_regulation of Negative_regulation of Slc1a3 4 0.45 0.38 5.87 100.00
54 INT6431 Positive_regulation of Ass1 36 0.24 8.08 10.43 100.00
55 INT13055 Gene_expression of SNORD50A 1 0.58 0.1 2.12 100.00
56 INT304002 Regulation of Gene_expression of S1pr4 1 0.13 1.42 1.86 100.00
57 INT686 Negative_regulation of Sct 35 0.59 9.59 11.32 100.00
58 INT5513 Negative_regulation of Pomc 295 0.59 60.9 158.63 100.00
59 INT57709 Positive_regulation of Gstp2 2 0.60 0.87 1.1 100.00
60 INT68592 Negative_regulation of asa 8 0.37 3.75 2.1 100.00
61 INT100658 Negative_regulation of Positive_regulation of Grin2b 7 0.41 1.39 6.17 100.00
62 INT52250 Positive_regulation of Regulation of CALCA 1 0.48 0.08 1.43 100.00
63 INT2490 Regulation of Sct 44 0.62 9.45 13.11 100.00
64 INT304005 Negative_regulation of Localization of S1pr4 1 0.12 0.51 1.67 100.00
65 INT142528 Positive_regulation of Gene_expression of GTS 1 0.03 0 1.63 100.00
66 INT53063 Positive_regulation of Slc1a1 10 0.70 3.23 9.89 100.00
67 INT105198 Positive_regulation of Negative_regulation of GTS 3 0.26 0.58 4.18 100.00
68 INT152862 Regulation of Binding of S100a9 1 0.42 2.11 1.83 100.00
69 INT989 Negative_regulation of Trh 90 0.59 15.45 43.63 100.00
70 INT9567 Binding of Nts 10 0.44 2.14 5.89 100.00
71 INT130280 Positive_regulation of Gene_expression of Gad2 7 0.69 8.13 9.55 100.00
72 INT76621 Positive_regulation of Cnr2 32 0.69 17.77 26.57 100.00
73 INT83443 Regulation of Regulation of DPH1 1 0.04 0.35 0.62 100.00
74 INT91979 Positive_regulation of Positive_regulation of Nkx1-1 3 0.23 2.06 3.06 100.00
75 INT53376 Positive_regulation of Regulation of Edn3 1 0.48 0 0.19 100.00
76 INT53372 Positive_regulation of Regulation of Edn1 1 0.50 0 0.19 100.00
77 INT55640 Gene_expression of CHRM1 7 0.44 2.24 1.89 100.00
78 INT80227 Regulation of Gene_expression of Hmox1 12 0.44 11.04 1.61 100.00
79 INT4060 Gene_expression of Bche 17 0.70 5.23 6.59 100.00
80 INT105195 Positive_regulation of Negative_regulation of Slc1a1 2 0.40 0.48 3.4 100.00
81 INT118350 Negative_regulation of Chga 2 0.42 1.64 0.71 100.00
82 INT79621 Regulation of DEM1 1 0.08 0.2 0.79 100.00
83 INT21323 Gene_expression of Gm5195 1 0.16 0.15 0.99 100.00
84 INT18543 Negative_regulation of ECT 20 0.37 8.4 5.25 100.00
85 INT56014 Gene_expression of Pzp 4 0.52 0.22 1.61 100.00
86 INT74270 Positive_regulation of Regulation of Adk 1 0.35 0.58 0.95 100.00
87 INT10705 Binding of Il1b 9 0.36 2.8 5.53 100.00
88 INT131530 Gene_expression of Bst1 2 0.26 4.21 1.22 100.00
89 INT72076 Regulation of Regulation of Pnoc 1 0.32 0.09 2.68 100.00
90 INT6764 Regulation of Regulation of Oprl1 5 0.45 0.58 5.28 100.00
91 INT39984 Positive_regulation of Ccbe1 1 0.00 0 1.02 100.00
92 INT50606 Regulation of Cpa5 1 0.14 0 0.69 100.00
93 INT96968 Regulation of Positive_regulation of GNAI1 1 0.07 0.17 0.66 100.00
94 INT56015 Regulation of Gene_expression of Pzp 1 0.18 0 0.41 100.00
95 INT167669 Binding of Mir881 1 0.00 0.1 0.31 100.00
96 INT5895 Gene_expression of Oprm1 525 0.78 120.67 407.29 99.98
97 INT26472 Regulation of Oprm1 191 0.62 35.84 173.1 99.98
98 INT5591 Regulation of Gene_expression of Fos 425 0.62 129.06 265.78 99.98
99 INT6293 Gene_expression of Oprm1 312 0.78 48.73 215.61 99.98
100 INT5771 Binding of Oprd1 37 0.48 2.6 27.54 99.98
101 INT74377 Regulation of Cnr1 38 0.59 16.93 24.77 99.98
102 INT15796 Regulation of IL2 66 0.61 25.43 20.62 99.98
103 INT68970 Positive_regulation of Pnoc 33 0.67 9.29 19.08 99.98
104 INT2149 Positive_regulation of Oxt 181 0.70 24.8 85.43 99.98
105 INT65078 Negative_regulation of Pnoc 64 0.59 15.48 59.81 99.98
106 INT9382 Regulation of TRPV1 149 0.62 53.99 77.46 99.98
107 INT8732 Positive_regulation of Gene_expression of Oprm1 76 0.70 22.59 58.83 99.98
108 INT5039 Positive_regulation of Gal 67 0.68 27.97 37.36 99.98
109 INT104705 Regulation of Msh3 4 0.28 0.1 3.51 99.98
110 INT66416 Regulation of Pnoc 66 0.61 17.32 68.91 99.98
111 INT105754 Regulation of St13 8 0.28 0.75 11.41 99.98
112 INT1414 Regulation of Oprl1 169 0.62 32.05 139.99 99.98
113 INT101697 Negative_regulation of Ang2 4 0.16 0.55 1.42 99.98
114 INT2155 Negative_regulation of Sst 111 0.59 16.58 77.74 99.98
115 INT22794 Regulation of Gt(pU21)50Imeg 4 0.02 0.14 7.45 99.98
116 INT68640 Regulation of Pnoc 18 0.54 7.6 17.27 99.98
117 INT35307 Regulation of Adk 11 0.35 3.21 7.79 99.98
118 INT57088 Negative_regulation of Slc14a2 9 0.19 2.27 2.39 99.98
119 INT202521 Negative_regulation of Negative_regulation of Slc14a2 1 0.05 0.2 0.75 99.98
120 INT104706 Regulation of Em 4 0.42 0.25 4.01 99.98
121 INT3217 Regulation of Ins1 154 0.62 87.11 27.29 99.98
122 INT48006 Negative_regulation of Oprk1 27 0.58 10.14 19.11 99.98
123 INT19580 Binding of Pag1 24 0.30 15.13 20.88 99.98
124 INT103666 Regulation of Mors1 20 0.28 3.6 18.86 99.98
125 INT172458 Regulation of Gopc 155 0.53 62.57 24.86 99.98
126 INT75153 Regulation of Olr594 1 0.21 0.18 0.59 99.98
127 INT73046 Negative_regulation of Rere 4 0.42 0.32 4.58 99.98
128 INT39986 Regulation of Agtr2 13 0.45 10.39 3.55 99.98
129 INT53948 Regulation of Gene_expression of Cpox 40 0.51 20.97 13.87 99.98
130 INT8248 Binding of Adra2a 43 0.48 6.72 22.17 99.98
131 INT390 Positive_regulation of Agt 170 0.70 61.47 36.08 99.98
132 INT5337 Negative_regulation of Npy 87 0.59 19.6 46.75 99.98
133 INT5967 Negative_regulation of Il1a 51 0.57 27.09 18.24 99.98
134 INT73169 Localization of Mir343 2 0.46 0 0.65 99.98
135 INT167050 Negative_regulation of Gt(pU21)50Imeg 1 0.01 0 2.28 99.98
136 INT160994 Negative_regulation of St13 9 0.20 4.83 3.71 99.98
137 INT29352 Negative_regulation of Oprd1 16 0.58 6.51 14.6 99.98
138 INT113317 Regulation of Cnr2 17 0.52 10.27 10.68 99.98
139 INT118926 Regulation of PTGES 17 0.51 5.79 4.69 99.98
140 INT304004 Localization of S1pr4 1 0.21 0.5 1.65 99.98
141 INT4207 Regulation of Avp 267 0.62 63.72 115.33 99.98
142 INT15202 Regulation of Tacr1 26 0.60 9.65 16.48 99.98
143 INT52633 Negative_regulation of Notch1 4 0.42 2.99 1.84 99.98
144 INT18656 Binding of Tal2 2 0.30 0 2.45 99.98
145 INT2389 Regulation of PTGS1 86 0.61 31.23 28.95 99.98
146 INT48008 Negative_regulation of Pde6b 9 0.15 6.12 4.11 99.98
147 INT26218 Gene_expression of Gt(pU21)50Imeg 3 0.02 0.26 4.63 99.98
148 INT42348 Regulation of Pes1 1 0.23 0 0.62 99.98
149 INT61806 Regulation of Negative_regulation of Ada 1 0.30 0.63 1.89 99.98
150 INT83444 Regulation of DPH1 2 0.09 0.35 0.62 99.98
151 INT17803 Regulation of Edn1 14 0.54 4.75 4.71 99.98
152 INT53373 Regulation of Edn3 2 0.45 1.38 0.18 99.98
153 INT73128 Regulation of Pde5a 7 0.37 4.42 4.27 99.98
154 INT2976 Regulation of Bche 29 0.45 8.56 9.42 99.98
155 INT48907 Positive_regulation of Gene_expression of Oprm1 53 0.69 8.55 33.52 99.98
156 INT92450 Regulation of Igkv12-66 1 0.13 0 0.34 99.98
157 INT33661 Regulation of Tbpl1 7 0.44 5.36 3.26 99.98
158 INT33662 Regulation of Lyz2 1 0.04 0.08 0.66 99.98
159 INT161266 Positive_regulation of Ripk1 1 0.49 0.09 0.47 99.98
160 INT129585 Gene_expression of St13 17 0.59 4.46 9.3 99.98
161 INT89854 Regulation of Nos2 49 0.61 42.58 24.1 99.98
162 INT49172 Regulation of Nos1 43 0.52 27.53 23.66 99.98
163 INT9490 Regulation of Mme 44 0.56 6.69 19.21 99.98
164 INT54771 Regulation of Gstp2 1 0.06 0 0.78 99.98
165 INT79195 Binding of Em 2 0.11 0.1 0.67 99.98
166 INT74271 Regulation of Negative_regulation of Adk 1 0.32 0.52 0.83 99.98
167 INT2055 Regulation of Gnrh1 185 0.62 23.65 71.26 99.98
168 INT69762 Negative_regulation of Jag2 1 0.42 0.07 0.3 99.98
169 INT198406 Localization of C2 5 0.65 1.42 1.01 99.98
170 INT196095 Localization of Arhgap4 4 0.73 0.31 0.95 99.98
171 INT14911 Gene_expression of Ddx20 6 0.05 0.26 3.06 99.98
172 INT56689 Gene_expression of LOC502940 4 0.18 0.77 1.31 99.98
173 INT143920 Positive_regulation of Gene_expression of Ddx20 1 0.02 0.27 0.93 99.98
174 INT54126 Negative_regulation of Cd81 5 0.38 0.27 2.7 99.98
175 INT8755 Regulation of Tac2 12 0.62 0.56 5.27 99.98
176 INT168444 Positive_regulation of Positive_regulation of C2 2 0.43 0.93 0.85 99.98
177 INT294813 Positive_regulation of Positive_regulation of Arhgap4 1 0.43 0.28 0.39 99.98
178 INT8056 Regulation of Positive_regulation of Penk 34 0.59 4.71 17.66 99.98
179 INT21552 Regulation of Drd1a 10 0.57 3.7 6.05 99.98
180 INT74815 Binding of Grm5 11 0.36 3.62 4.25 99.98
181 INT74814 Binding of Grm1 5 0.45 2.69 4.1 99.98
182 INT7437 Gene_expression of CFP 21 0.65 4.93 3.89 99.98
183 INT65190 Regulation of Umod 2 0.44 0.51 1.26 99.98
184 INT74166 Positive_regulation of C2 10 0.55 2.83 1.05 99.98
185 INT207306 Positive_regulation of Arhgap4 1 0.43 0.27 0.36 99.98
186 INT96533 Gene_expression of Slc1a3 72 0.78 26.85 55.31 99.96
187 INT8650 Gene_expression of Gal 152 0.78 61.97 81.72 99.96
188 INT15102 Gene_expression of Trim13 18 0.67 0.43 15.49 99.96
189 INT12095 Negative_regulation of Edn1 26 0.59 12.01 8.79 99.96
190 INT158 Localization of Prl 2431 0.81 378.96 952.2 99.96
191 INT107329 Gene_expression of Me3 2 0.19 1.42 4.91 99.96
192 INT13498 Gene_expression of Atxn2l 16 0.52 1.24 13.73 99.96
193 INT128013 Negative_regulation of Gene_expression of Slc1a3 20 0.59 10.65 16.13 99.96
194 INT159127 Gene_expression of Nps 49 0.75 16.91 12.06 99.96
195 INT10272 Gene_expression of Il1b 194 0.78 121.02 103.03 99.96
196 INT22000 Positive_regulation of Sst 25 0.70 14.82 13.6 99.96
197 INT154697 Negative_regulation of Fpr2l 3 0.31 2.62 2.43 99.96
198 INT81226 Gene_expression of Adk 9 0.64 9.28 4.81 99.96
199 INT29708 Gene_expression of Gria1 177 0.78 56.36 77.37 99.96
200 INT32791 Gene_expression of Dpp6 5 0.76 2.51 4.04 99.96
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