P:Bradykinin

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pChart

Pain Term
Category Molecule
Synonyms None
Pain Specific No
Documents 2261
Hot Single Events 200
Hot Interactions 200

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Bradykinin. They are ordered first by their pain relevance and then by number of times they were reported for Bradykinin. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT7190 Syt17 Positive_regulation of Ctsb 1 0.16 0 3.23 100.00
2 INT7193 Abl2 Positive_regulation of Ctsb 1 0.21 0 3.21 100.00
3 INT7195 Negative_regulation of Syt17 Positive_regulation of Ctsb 1 0.10 0 2.25 100.00
4 INT162343 Positive_regulation of KCNMA1 Positive_regulation of ACE 1 0.06 1.25 1.23 100.00
5 INT162344 KCNMA1 Positive_regulation of ACE 1 0.06 1.25 1.23 100.00
6 INT121190 KCNMA1 Positive_regulation of Gene_expression of IL6 1 0.03 0.54 1.24 100.00
7 INT121189 KCNMA1 Positive_regulation of IL6 1 0.04 0.54 1.23 100.00
8 INT121191 KCNMA1 Positive_regulation of Phosphorylation of MAPK1 1 0.06 0.61 1.18 100.00
9 INT61443 Binding of KNG1 and Tyr 1 0.00 0 1.46 100.00
10 INT7191 Negative_regulation of Abl2 Positive_regulation of Ctsb 1 0.13 0 1.04 100.00
11 INT7201 Syt17 Negative_regulation of Syt17 Positive_regulation of Ctsb 1 0.03 0 1.04 100.00
12 INT7199 Syt17 Regulation of Syt17 Positive_regulation of Ctsb 1 0.02 0 1.05 100.00
13 INT7198 Magt1 Negative_regulation of Syt17 Positive_regulation of Ctsb 1 0.03 0 1.22 100.00
14 INT7200 Reg3b Negative_regulation of Syt17 Positive_regulation of Ctsb 1 0.01 0 1.22 100.00
15 INT303690 KNG1 Positive_regulation of CPOX 1 0.01 0.76 0.96 100.00
16 INT170037 Ngf Regulation of Gene_expression of DRGX 1 0.01 1.37 2.46 100.00
17 INT170038 Gtf3a Regulation of Gene_expression of DRGX 1 0.00 1.36 2.46 100.00
18 INT5544 Ptpro Regulation of Syt17 1 0.05 0 0.6 100.00
19 INT66713 Binding of BDKRB1 and KNG1 2 0.22 0.39 1.53 100.00
20 INT54559 KCNMA1 Positive_regulation of Localization of TBXA2R 1 0.01 0.07 0.81 100.00
21 INT154685 Syt17 Positive_regulation of Trpa1 1 0.32 0.71 1.4 100.00
22 INT66711 Negative_regulation of Binding of BDKRB2 and KNG1 1 0.07 0.22 0.97 100.00
23 INT66712 Binding of BDKRB2 and KNG1 1 0.06 0.22 0.97 100.00
24 INT66714 Negative_regulation of Binding of BDKRB1 and KNG1 1 0.13 0.22 0.96 100.00
25 INT332699 Binding of KNG1 and TRGC1 1 0.16 3.37 0.75 100.00
26 INT324927 Syt17 Positive_regulation of Bdkrb1 1 0.04 4.29 2.96 100.00
27 INT121188 Negative_regulation of KCNMA1 Positive_regulation of IL6 1 0.04 0.3 0.63 100.00
28 INT337323 KNG1 Positive_regulation of PRKCA 1 0.15 0.17 0.62 100.00
29 INT96008 Binding of KNG1 and EBP 1 0.01 0.15 0.88 100.00
30 INT96010 KNG1 Positive_regulation of Binding of MTG1 1 0.32 0.15 0.88 100.00
31 INT267625 Binding of KNG1 and Klk1 2 0.21 2.23 0.61 100.00
32 INT96009 KNG1 Positive_regulation of MTG1 1 0.32 0.15 0.88 100.00
33 INT261652 Binding of MAPK1 and PSEN1 1 0.22 1.25 0.41 100.00
34 INT125950 Syt17 Regulation of Trpv1 1 0.11 0.43 1.28 100.00
35 INT181619 ACE Positive_regulation of KNG1 1 0.33 0.97 0.58 100.00
36 INT126640 Negative_regulation of KNG1 Positive_regulation of Alox15 1 0.14 0.62 1.36 100.00
37 INT126639 KNG1 Positive_regulation of Alox15 1 0.17 0.62 1.36 100.00
38 INT39091 Negative_regulation of Penk Positive_regulation of Localization of Ren 1 0.30 0 0.74 100.00
39 INT140790 Positive_regulation of Ptger3 Negative_regulation of Negative_regulation of Bdkrb2 1 0.00 0.07 0.76 100.00
40 INT121457 KNG1 Positive_regulation of Trpv1 1 0.16 0.91 1.33 100.00
41 INT33415 KNG1 Positive_regulation of GBP1 1 0.02 0.43 0.51 100.00
42 INT230852 ACE Regulation of KNG1 2 0.03 0.72 0.32 100.00
43 INT26552 Gene_expression of Mras Positive_regulation of Gene_expression of KNG1 1 0.03 0.07 0.36 100.00
44 INT230855 KNG1 Regulation of NOS1 2 0.03 0.94 0.33 100.00
45 INT290269 KNG1 Positive_regulation of Binding of MID1 1 0.02 1.06 0.41 100.00
46 INT290270 KNG1 Positive_regulation of MID1 1 0.02 1.06 0.41 100.00
47 INT261648 BDKRB1 Regulation of PRKCA 1 0.03 1.9 0.47 100.00
48 INT324926 Ptpro Positive_regulation of Bdkrb2 1 0.01 2.25 1.5 100.00
49 INT196618 Binding of KNG1 and Positive_regulation of NA 1 0.01 0.19 0.32 100.00
50 INT196623 Binding of KNG1 and Positive_regulation of DNAH8 1 0.01 0.19 0.32 100.00
51 INT196613 Binding of KNG1 and NA 1 0.01 0.08 0.27 100.00
52 INT196626 Binding of DNAH8 and KNG1 1 0.00 0.08 0.27 100.00
53 INT196641 Binding of KNG1 and Negative_regulation of DNAH8 1 0.01 0.19 0.29 100.00
54 INT196612 Binding of KNG1 and Negative_regulation of NA 1 0.01 0.19 0.29 100.00
55 INT107028 KNG1 Regulation of Des 1 0.01 1.7 0.76 100.00
56 INT265830 KNG1 Positive_regulation of Localization of BGN 1 0.02 0.33 0.27 100.00
57 INT24967 Olr567 Regulation of Localization of Syt17 1 0.11 0.62 0.71 100.00
58 INT39077 Agt Negative_regulation of Prss12 1 0.05 0.44 0.46 100.00
59 INT84369 Ngf Positive_regulation of KNG1 1 0.04 0.29 0.89 100.00
60 INT39078 Binding of Agt and Penk 1 0.24 0.42 0.48 100.00
61 INT136008 Binding of BDKRB2 and INSRR 1 0.01 0.17 0.34 100.00
62 INT136007 Binding of INSRR and KNG1 1 0.00 0.17 0.34 100.00
63 INT303689 Regulation of KNG1 Positive_regulation of AHR 1 0.03 0.99 0.69 100.00
64 INT96472 KNG1 Positive_regulation of Gene_expression of TRPV1 1 0.01 0.22 0.64 100.00
65 INT303691 KNG1 Positive_regulation of AHR 1 0.03 0.98 0.69 100.00
66 INT265828 ACE Regulation of Gene_expression of KNG1 1 0.32 0.83 0.22 100.00
67 INT39093 Negative_regulation of Prss12 Positive_regulation of Localization of Ren 1 0.10 0 0.37 100.00
68 INT39094 Negative_regulation of Nts Positive_regulation of Localization of Ren 1 0.16 0 0.37 100.00
69 INT281896 KNG1 Regulation of Binding of KNG1 and NOS3 1 0.02 0.17 0.22 100.00
70 INT281901 Binding of KNG1 and NOS3 1 0.05 0.17 0.22 100.00
71 INT121460 KNG1 Positive_regulation of Bdkrb2 1 0.08 0.44 0.62 100.00
72 INT121459 Bdkrb2 Positive_regulation of KNG1 1 0.09 0.44 0.62 100.00
73 INT121458 KNG1 Positive_regulation of Localization of Trpv1 1 0.16 0.43 0.69 100.00
74 INT239238 Ace Positive_regulation of Protein_catabolism of KNG1 1 0.01 0.46 0.24 100.00
75 INT267624 Klk1 Positive_regulation of KNG1 1 0.05 0.52 0.25 100.00
76 INT299989 PRKCA Positive_regulation of Gene_expression of IL8 1 0.04 0.45 0.67 100.00
77 INT332700 Binding of F12 and KNG1 1 0.15 1.05 0.21 100.00
78 INT95546 KNG1 Positive_regulation of Ptgir 1 0.02 0.93 0.64 100.00
79 INT337327 KNG1 Positive_regulation of BDKRB2 1 0.21 0.4 0.32 100.00
80 INT327090 Negative_regulation of F12 Negative_regulation of Gene_expression of KNG1 1 0.00 0.51 0.45 100.00
81 INT44112 Agt Regulation of Penk 1 0.08 0 0.35 100.00
82 INT73538 Ngf Positive_regulation of Ngfr 2 0.41 1.05 0.85 100.00
83 INT73537 Ntf3 Positive_regulation of Ngfr 1 0.21 0.1 0.38 100.00
84 INT150636 Binding of KNG1 and CD177 1 0.10 0.37 0.79 100.00
85 INT73536 Ngf Regulation of Ngfr 1 0.22 0.08 0.37 100.00
86 INT85511 Binding of KNG1 and Bdkrb2 1 0.54 0.51 0.4 100.00
87 INT44983 Ltc4s Positive_regulation of Rara 1 0.01 0.15 0.33 100.00
88 INT44985 KNG1 Positive_regulation of Rara 1 0.00 0.15 0.32 100.00
89 INT107635 KNG1 Regulation of Slc25a1 1 0.00 0.1 0.13 100.00
90 INT107622 KNG1 Regulation of AP4B1 1 0.19 0.1 0.13 100.00
91 INT82094 Binding of KNG1 and CLPP 1 0.03 0.42 0.21 100.00
92 INT104855 Prkaca Regulation of TRPV1 3 0.06 1.52 1.92 100.00
93 INT126641 Binding of KNG1 and Bdkrb2 1 0.11 0.42 0.55 100.00
94 INT96245 Negative_regulation of Tnf Positive_regulation of KNG1 1 0.01 0.59 0.45 100.00
95 INT96246 Tnf Positive_regulation of KNG1 1 0.01 0.59 0.45 100.00
96 INT228454 Ngf Positive_regulation of Phosphorylation of Trpv1 1 0.39 2.97 2.26 100.00
97 INT303722 KNG1 Positive_regulation of Bdkrb2 1 0.01 0.7 0.52 100.00
98 INT73681 Regulation of KNG1 Positive_regulation of ALB 1 0.30 0.38 0.99 100.00
99 INT303721 KNG1 Positive_regulation of Bdkrb1 1 0.05 0.75 0.52 100.00
100 INT73680 KNG1 Positive_regulation of ALB 1 0.51 0.38 0.98 100.00
101 INT281903 BDKRB1 Positive_regulation of KNG1 1 0.03 0.32 0.21 100.00
102 INT129415 KNG1 Positive_regulation of Trpv1 1 0.05 0.39 0.76 100.00
103 INT232018 Binding of SERPING1 and KNG1 1 0.15 0.81 0.14 100.00
104 INT172248 Binding of KNG1 and NCOR2 1 0.02 0.19 0.52 100.00
105 INT34005 YY1 Regulation of KNG1 1 0.04 0.38 0.63 100.00
106 INT35216 Binding of KNG1 and Thop1 1 0.01 0 0.32 100.00
107 INT225690 KNG1 Positive_regulation of TRPV1 1 0.42 0.7 0.83 100.00
108 INT58663 Binding of KNG1 and Ugt1a2 1 0.02 0.4 0.47 100.00
109 INT66243 KNG1 Positive_regulation of Ptgis 1 0.01 0 0.3 100.00
110 INT267596 KNG1 Positive_regulation of Gene_expression of PLA2G6 1 0.01 0.87 0.25 100.00
111 INT201092 Binding of KNG1 and NGF 1 0.00 0.31 0.43 100.00
112 INT201120 Binding of KNG1 and Par2 1 0.00 0.3 0.42 100.00
113 INT44984 KNG1 Regulation of Ltc4s 1 0.01 0.17 0.3 100.00
114 INT166945 Ngf Positive_regulation of Trpv1 1 0.01 0.47 1.88 100.00
115 INT166947 Ngf Positive_regulation of KNG1 1 0.00 0.47 1.86 100.00
116 INT94617 KNG1 Positive_regulation of Localization of Calca 1 0.00 0.75 1.7 100.00
117 INT94618 KNG1 Positive_regulation of Calca 1 0.00 0.75 1.66 100.00
118 INT193322 KNG1 Positive_regulation of Prh1 1 0.00 0.51 0.83 100.00
119 INT34840 Binding of KNG1 and PDYN 1 0.01 0 0.61 100.00
120 INT120348 Negative_regulation of Binding of DES and MYC 1 0.06 0.18 0.58 100.00
121 INT120349 Binding of BDKRB1 and DES 1 0.05 0.17 0.58 100.00
122 INT120350 Binding of DES and MYC 1 0.05 0.17 0.58 100.00
123 INT120347 Binding of KNG1 and MYC 1 0.21 0.17 0.58 100.00
124 INT229222 Negative_regulation of ACE Negative_regulation of Protein_catabolism of KNG1 1 0.06 0.53 0.37 100.00
125 INT170994 KNG1 Positive_regulation of Gene_expression of IL8 1 0.04 0.45 0.32 100.00
126 INT64726 Ace Negative_regulation of KNG1 1 0.01 0.26 0.25 100.00
127 INT64727 Ace Positive_regulation of KNG1 1 0.01 0.26 0.25 100.00
128 INT191500 ACE Positive_regulation of Localization of KNG1 1 0.10 0.17 0.24 100.00
129 INT104702 KNG1 Negative_regulation of Anpep 1 0.11 0.47 0.19 100.00
130 INT326464 KNG1 Positive_regulation of SERPING1 1 0.19 1.53 0.18 100.00
131 INT269322 TMPO Positive_regulation of Positive_regulation of NOS1 1 0.03 0 0.18 100.00
132 INT329324 KNG1 Positive_regulation of Localization of ecs 1 0.00 1.16 0.17 100.00
133 INT77159 Positive_regulation of KLK1 Positive_regulation of KNG1 1 0.04 0.28 0.15 100.00
134 INT221254 Binding of KNG1 and Akt1 1 0.00 0.13 0.13 100.00
135 INT329317 ACE Regulation of Positive_regulation of KNG1 1 0.02 1.05 0.12 100.00
136 INT229364 Ace Positive_regulation of Protein_catabolism of KNG1 1 0.02 0.86 0.11 100.00
137 INT336990 Binding of AGTR1 and BDKRB2 1 0.03 0 0.1 100.00
138 INT281898 Binding of ANG and ACE Positive_regulation of KNG1 1 0.03 0.37 0.1 100.00
139 INT196627 IL1B Regulation of DNAH8 1 0.00 0.63 0.09 100.00
140 INT196643 IL1B Regulation of NA 1 0.00 0.63 0.09 100.00
141 INT196619 KNG1 Regulation of DNAH8 1 0.00 0.62 0.09 100.00
142 INT265829 ACE Positive_regulation of Protein_catabolism of KNG1 1 0.33 0.73 0.09 100.00
143 INT196645 KNG1 Regulation of NA 1 0.00 0.62 0.09 100.00
144 INT232009 Positive_regulation of F12 Negative_regulation of Localization of KNG1 1 0.01 0.19 0.05 100.00
145 INT196605 Binding of DNAH8 and SPANXB1 Positive_regulation of DNAH8 1 0.00 0.08 0.3 99.96
146 INT196604 Binding of DNAH8 and SPANXB1 Positive_regulation of NA 1 0.00 0.08 0.3 99.96
147 INT196616 Binding of NA and SPANXB1 1 0.00 0.08 0.27 99.96
148 INT196637 Binding of DNAH8 and SPANXB1 1 0.00 0.08 0.27 99.96
149 INT261650 LGR6 Positive_regulation of MAPK1 1 0.04 0.71 0.24 99.92
150 INT56990 Cat Regulation of Efs 1 0.26 0 1.05 99.90
151 INT27621 Avp Positive_regulation of Protein_catabolism of Mbis1 1 0.00 0 1.18 99.90
152 INT96475 Ngf Positive_regulation of Gene_expression of TRPV1 1 0.03 0.22 0.63 99.90
153 INT39095 Negative_regulation of Agt Positive_regulation of Localization of Ren 1 0.38 0 0.73 99.88
154 INT354224 Bdnf Positive_regulation of Transcription of Accn3 1 0.09 1.04 0.95 99.88
155 INT16643 Nppa Regulation of Rabep2 1 0.13 0.07 0.55 99.84
156 INT267591 CYSLTR1 Positive_regulation of Gene_expression of PLA2G6 1 0.00 0.87 0.25 99.76
157 INT27622 LOC360919 Positive_regulation of Protein_catabolism of Mbis1 1 0.00 0 1.18 99.70
158 INT39092 Agt Negative_regulation of Ren 1 0.39 0 0.37 99.68
159 INT39096 Prss12 Negative_regulation of Ren 1 0.12 0 0.37 99.68
160 INT51167 Defb35 Regulation of Localization of Ins1 1 0.02 0.08 0.42 99.68
161 INT83094 IL1B Positive_regulation of Positive_regulation of BDKRB1 1 0.45 0.2 0.81 99.66
162 INT332701 Binding of BDKRB1 and BDKRB2 1 0.01 0.5 0.39 99.62
163 INT267584 TNF Positive_regulation of Gene_expression of PLA2G6 1 0.08 0.87 0.25 99.52
164 INT83093 IL1B Positive_regulation of BDKRB1 1 0.51 0.44 1.65 99.46
165 INT39076 Prss12 Regulation of Penk 1 0.04 0.44 0.46 99.38
166 INT267632 Il1 Positive_regulation of Gene_expression of PLA2G6 1 0.00 0.86 0.25 99.32
167 INT102885 Binding of ANG and ACE 2 0.17 0.37 0.13 99.24
168 INT51205 Binding of OPRK1 and PDYN 7 0.00 2.01 7.8 99.16
169 INT108413 Binding of OPRK1 and Oprd1 1 0.00 0.08 1.04 99.16
170 INT7202 Uba3 Negative_regulation of Abl2 Positive_regulation of Ctsb 1 0.00 0 1.2 99.12
171 INT130167 Trpv1 Regulation of Localization of Calca 2 0.38 0.69 1.03 99.12
172 INT262575 Trpv1 Positive_regulation of Prkca 1 0.13 0.17 0.44 99.08
173 INT107634 Slc25a1 Regulation of AP4B1 1 0.00 0.1 0.13 98.84
174 INT135582 Prok2 Positive_regulation of Localization of Prkce 1 0.06 1.02 1.87 98.84
175 INT346835 Gene_expression of Efnb2 Positive_regulation of Phosphorylation of Grin2b 1 0.27 1.07 1.03 98.50
176 INT161455 Mmp7 Positive_regulation of Egfr 1 0.03 0.19 0.92 98.48
177 INT114341 Agt Positive_regulation of AGT 3 0.01 1.15 0.43 98.40
178 INT332707 Binding of TRGC1 and Klk1 1 0.32 1.64 0.36 98.28
179 INT334893 ACE Negative_regulation of Gene_expression of AGT 1 0.03 1.41 0.1 98.20
180 INT284785 Gch1 Regulation of Bh4p 1 0.00 1.48 1.54 98.00
181 INT329325 ACE Regulation of Negative_regulation of Agtr2 1 0.01 0.93 0.12 97.92
182 INT263236 DAG1 Positive_regulation of Prkcg 2 0.01 0.31 0.7 97.68
183 INT293124 Agtr1a Regulation of Gene_expression of Aqp2 1 0.17 0.36 0.14 97.64
184 INT293125 Agt Regulation of Avp Regulation of Aqp2 1 0.04 0.36 0.14 97.64
185 INT293119 Agtr1a Regulation of Positive_regulation of Crh 1 0.12 0.37 0.14 97.64
186 INT293115 Agt Regulation of Positive_regulation of Crh 1 0.16 0.37 0.14 97.64
187 INT293117 Agt Regulation of Gene_expression of Aqp2 1 0.23 0.36 0.14 97.64
188 INT293126 Agtr1a Regulation of Avp Regulation of Aqp2 1 0.03 0.36 0.14 97.64
189 INT293123 Agtr1a Regulation of Negative_regulation of Agt 1 0.14 0.25 0.14 97.64
190 INT265826 Binding of ACE and SERPINE1 1 0.24 1.08 0.3 97.60
191 INT342633 ACE Regulation of Gene_expression of AGT 1 0.01 0.14 0.46 97.56
192 INT227543 Mtx1 Positive_regulation of Prep 1 0.22 1.19 1.92 97.56
193 INT227542 Mtx1 Positive_regulation of Binding of Prep 1 0.23 1.2 1.92 97.56
194 INT153879 Gast Positive_regulation of Positive_regulation of TRPV1 1 0.09 0.35 0.76 97.40
195 INT299986 BDKRB2 Regulation of Gene_expression of SPANXB1 1 0.29 0.51 1.02 97.36
196 INT338043 F2 Positive_regulation of Localization of Prkca 1 0.04 0.1 0.2 97.28
197 INT227545 Hspa9 Positive_regulation of Prep 1 0.18 0.59 0.96 96.92
198 INT173353 Gnaq Positive_regulation of CDK20 Positive_regulation of Positive_regulation of PLA2G6 1 0.02 0 0.22 96.80
199 INT338042 F2r Positive_regulation of Localization of Prkca 1 0.06 0.1 0.2 96.76
200 INT74599 YY1 Negative_regulation of ADCY1 2 0.36 0.31 0.67 96.60

Single Events

The table below shows the top 200 pain related interactions that have been reported for Bradykinin. They are ordered first by their pain relevance and then by number of times they were reported in Bradykinin. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT11491 Positive_regulation of KNG1 128 0.67 60.41 58.74 100.00
2 INT8357 Gene_expression of KNG1 153 0.75 77.26 68.66 100.00
3 INT7134 Localization of KNG1 127 0.79 65.73 67.97 100.00
4 INT71789 Positive_regulation of MAPK1 396 0.70 234.44 89.27 100.00
5 INT3167 Binding of KNG1 48 0.48 23.26 26.77 100.00
6 INT4758 Positive_regulation of Localization of Calca 557 0.70 138.55 411.04 100.00
7 INT3076 Regulation of KNG1 52 0.60 20.39 27.89 100.00
8 INT608 Negative_regulation of KNG1 98 0.43 72.36 31.23 100.00
9 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48 100.00
10 INT14204 Protein_catabolism of KNG1 41 0.96 20.94 11.47 100.00
11 INT6848 Gene_expression of BDKRB2 40 0.75 17.19 20.04 100.00
12 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08 100.00
13 INT20266 Positive_regulation of Bdkrb1 60 0.69 63.64 56.59 100.00
14 INT66718 Positive_regulation of BDKRB2 21 0.64 9.89 11.6 100.00
15 INT59987 Gene_expression of BDKRB1 25 0.77 11.95 15.93 100.00
16 INT1179 Negative_regulation of Ace 157 0.59 67.03 30.46 100.00
17 INT6645 Positive_regulation of BDKRB1 14 0.66 12.17 13.79 100.00
18 INT37803 Positive_regulation of Bdkrb2 18 0.68 14.21 13.99 100.00
19 INT4759 Negative_regulation of Localization of Calca 294 0.59 82.62 226.45 100.00
20 INT28834 Positive_regulation of Bdkrb1 38 0.69 30.48 26.89 100.00
21 INT21647 Negative_regulation of Positive_regulation of KNG1 11 0.43 5.54 5.73 100.00
22 INT26551 Positive_regulation of Gene_expression of KNG1 19 0.67 11.05 7.98 100.00
23 INT6580 Negative_regulation of Ptgs1 929 0.59 381.53 376.26 100.00
24 INT80688 Positive_regulation of Positive_regulation of MAPK1 72 0.69 39.35 14.11 100.00
25 INT5050 Regulation of Localization of Calca 149 0.62 41.25 148.57 100.00
26 INT17386 Positive_regulation of Aia1 24 0.38 30.89 20.18 100.00
27 INT67975 Gene_expression of Bdkrb2 38 0.68 21.69 17.94 100.00
28 INT5008 Localization of Calca 204 0.81 80.35 125.16 100.00
29 INT2540 Negative_regulation of Calca 538 0.59 172.11 384.38 100.00
30 INT49643 Gene_expression of Bdkrb1 39 0.78 46.49 40.21 100.00
31 INT26348 Binding of Syt17 1 0.47 1.45 3.33 100.00
32 INT64202 Positive_regulation of Trpv1 643 0.70 249.66 397.42 100.00
33 INT48277 Regulation of BDKRB2 9 0.59 2.69 5.05 100.00
34 INT78827 Gene_expression of Bdkrb1 34 0.78 18.48 15.81 100.00
35 INT88223 Gene_expression of Bdkrb2 17 0.69 13.94 11.44 100.00
36 INT1533 Negative_regulation of AGT 105 0.42 46.54 16.92 100.00
37 INT142694 Positive_regulation of PGAP1 3 0.08 2.78 8.68 100.00
38 INT75525 Negative_regulation of Positive_regulation of MAPK1 40 0.59 25.15 11.15 100.00
39 INT56379 Positive_regulation of Syt17 7 0.55 7.16 9.05 100.00
40 INT24958 Gene_expression of Nkx1-1 106 0.74 51.29 76.88 100.00
41 INT9573 Regulation of Bdkrb2 9 0.43 6.04 8.41 100.00
42 INT3330 Gene_expression of AGT 149 0.76 98.65 22.73 100.00
43 INT58061 Gene_expression of Trpv1 1117 0.78 451.54 637.59 100.00
44 INT76660 Gene_expression of Trpv1 691 0.78 329.46 386.42 100.00
45 INT10659 Regulation of Syt17 3 0.39 2.16 4.53 100.00
46 INT193936 Positive_regulation of PSEN1 5 0.58 11.57 2.95 100.00
47 INT3926 Regulation of Bdkrb1 22 0.61 16.72 16.1 100.00
48 INT11479 Positive_regulation of KCNMA1 30 0.68 10.07 10.82 100.00
49 INT49217 Positive_regulation of Positive_regulation of KNG1 7 0.41 3.64 4.18 100.00
50 INT91462 Positive_regulation of Phosphorylation of MAPK1 99 0.67 40.28 18.99 100.00
51 INT18357 Gene_expression of TRPV1 825 0.78 307.11 382.81 100.00
52 INT130111 Regulation of Positive_regulation of MAPK1 14 0.36 11.01 5.9 100.00
53 INT52591 Gene_expression of KCNMA1 78 0.76 13.95 15.55 100.00
54 INT85510 Positive_regulation of Bdkrb2 23 0.70 12.08 12.68 100.00
55 INT59983 Regulation of BDKRB1 12 0.45 10.69 5.11 100.00
56 INT117601 Positive_regulation of Trpa1 174 0.70 72.41 71.9 100.00
57 INT11480 Positive_regulation of Localization of KNG1 15 0.30 6.39 5.5 100.00
58 INT76229 Binding of BDKRB1 5 0.33 1.46 3.66 100.00
59 INT170027 Gene_expression of Kcnmb1 1 0.01 4.12 3.95 100.00
60 INT66720 Negative_regulation of BDKRB2 5 0.57 1.92 3.11 100.00
61 INT3928 Localization of Bdkrb1 15 0.75 4.06 7.23 100.00
62 INT96622 Localization of Trpv1 110 0.81 59.82 63.25 100.00
63 INT70139 Regulation of Bdkrb1 6 0.52 8.41 6.66 100.00
64 INT162359 Gene_expression of KRT32 4 0.18 1.94 1.62 100.00
65 INT4824 Positive_regulation of Tacr1 169 0.70 66.1 123.46 100.00
66 INT62349 Negative_regulation of Protein_catabolism of KNG1 8 0.42 6.47 1.86 100.00
67 INT10138 Negative_regulation of Gene_expression of KNG1 13 0.57 9.57 4.9 100.00
68 INT65295 Negative_regulation of Bdkrb2 9 0.37 6.36 6.49 100.00
69 INT170032 Positive_regulation of Gene_expression of Acrbp 1 0.01 3.63 4 100.00
70 INT55224 Gene_expression of DRGX 99 0.31 67.55 67.63 100.00
71 INT8157 Binding of Tyr 14 0.09 0.64 5.89 100.00
72 INT7377 Regulation of Efs 6 0.39 0.93 2.91 100.00
73 INT8652 Protein_catabolism of Ace 10 0.94 4.7 2.74 100.00
74 INT88375 Negative_regulation of Localization of KNG1 4 0.39 1.12 1.91 100.00
75 INT11487 Positive_regulation of Localization of KCNMA1 4 0.06 1.5 2.31 100.00
76 INT11485 Localization of KCNMA1 7 0.09 1.81 2.6 100.00
77 INT162357 Protein_catabolism of KCNMA1 3 0.77 1.19 1.18 100.00
78 INT53347 Localization of BDKRB2 5 0.75 4.96 3.39 100.00
79 INT66716 Negative_regulation of BDKRB1 4 0.48 1.31 3 100.00
80 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15 100.00
81 INT3332 Protein_catabolism of AGT 23 0.87 3.17 4.39 100.00
82 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 100.00
83 INT162361 Positive_regulation of Gene_expression of KCNMA1 6 0.46 2.44 1.25 100.00
84 INT292 Localization of Penk 876 0.81 88.44 669.14 100.00
85 INT100497 Gene_expression of Aia1 9 0.25 11.78 7.51 100.00
86 INT63593 Binding of Ugt1a2 2 0.14 1.45 2.53 100.00
87 INT59986 Localization of BDKRB1 5 0.61 1.69 3.45 100.00
88 INT170029 Positive_regulation of Gene_expression of Aia1 3 0.22 2.79 2.9 100.00
89 INT72734 Gene_expression of Syt17 4 0.52 3.18 3.32 100.00
90 INT59984 Regulation of Gene_expression of BDKRB1 2 0.45 2.08 3.47 100.00
91 INT89054 Positive_regulation of Gene_expression of Trpv1 156 0.70 90.78 102.03 100.00
92 INT42038 Localization of ACE 26 0.80 8.88 7.06 100.00
93 INT70137 Regulation of Bdkrb2 10 0.27 5.45 4.62 100.00
94 INT38250 Negative_regulation of Syt17 3 0.38 1.83 2.92 100.00
95 INT2555 Positive_regulation of Localization of Penk 116 0.70 24.35 119.73 100.00
96 INT68844 Regulation of Positive_regulation of KNG1 2 0.44 2.22 1.02 100.00
97 INT55223 Regulation of Gene_expression of DRGX 6 0.09 3.77 5.15 100.00
98 INT6196 Regulation of Nppa 83 0.62 30.31 30.18 100.00
99 INT8700 Positive_regulation of Positive_regulation of Calca 56 0.67 21.69 53.66 100.00
100 INT7104 Binding of Bdkrb1 6 0.37 6.54 9.02 100.00
101 INT154683 Binding of Syt17 2 0.19 0.87 1.43 100.00
102 INT7175 Negative_regulation of Positive_regulation of Ctsb 1 0.34 0 0.86 100.00
103 INT126636 Binding of Bdkrb2 3 0.33 2.18 2.78 100.00
104 INT27467 Localization of Kng1 2 0.76 0.78 0.87 100.00
105 INT114748 Positive_regulation of Syt17 3 0.16 2.08 1.78 100.00
106 INT4857 Regulation of Tacr1 115 0.62 39.01 84.52 100.00
107 INT65119 Negative_regulation of Des 4 0.41 1.29 2.14 100.00
108 INT1771 Positive_regulation of Ace 31 0.68 10.47 7.46 100.00
109 INT75531 Regulation of MAPK1 70 0.61 34.39 15.42 100.00
110 INT20011 Regulation of NEUROD1 10 0.44 3.83 3.53 100.00
111 INT239234 Regulation of Protein_catabolism of KNG1 2 0.09 1.06 0.82 100.00
112 INT62556 Positive_regulation of Gene_expression of BDKRB1 3 0.46 0.65 1.98 100.00
113 INT61441 Negative_regulation of Gene_expression of Tyr 3 0.10 0.69 2.4 100.00
114 INT2260 Gene_expression of Tyr 30 0.49 7.05 11.31 100.00
115 INT24966 Localization of Syt17 5 0.46 1.89 3.66 100.00
116 INT74818 Transcription of KNG1 6 0.67 2.71 1.59 100.00
117 INT271464 Transcription of Ptpro 1 0.02 0.95 1.4 100.00
118 INT211591 Negative_regulation of PSEN1 14 0.57 5.73 3.26 100.00
119 INT52188 Positive_regulation of Des 2 0.16 1.56 1.63 100.00
120 INT68133 Localization of Fgf2 36 0.81 15.37 9.14 100.00
121 INT398 Localization of AGT 45 0.78 16.97 11.54 100.00
122 INT157366 Positive_regulation of Positive_regulation of KCNMA1 2 0.05 2.43 1.74 100.00
123 INT11616 Gene_expression of Thop1 10 0.74 0.32 3.34 100.00
124 INT13938 Positive_regulation of Nkx1-1 64 0.68 30.83 58.75 100.00
125 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87 100.00
126 INT59135 Positive_regulation of CTSB 15 0.67 7.53 2.53 100.00
127 INT59136 Negative_regulation of Positive_regulation of CTSB 3 0.41 2.02 1.11 100.00
128 INT193736 Regulation of Positive_regulation of CTSB 1 0.04 1.13 0.52 100.00
129 INT54560 Positive_regulation of Localization of TBXA2R 1 0.13 0 0.76 100.00
130 INT1395 Negative_regulation of Penk 537 0.59 87.33 389.81 100.00
131 INT79805 Phosphorylation of PRKCA 57 0.81 23.33 20.41 100.00
132 INT109431 Gene_expression of Trpa1 123 0.78 51.84 59.98 100.00
133 INT162362 Positive_regulation of Protein_catabolism of KCNMA1 1 0.05 0.61 0.6 100.00
134 INT20210 Localization of Ngf 69 0.79 46.22 38.57 100.00
135 INT162355 Regulation of Protein_catabolism of KCNMA1 1 0.05 0.59 0.59 100.00
136 INT6967 Regulation of KCNMA1 28 0.61 3.37 4.3 100.00
137 INT1116 Regulation of Ren 103 0.62 27.66 33.26 100.00
138 INT796 Gene_expression of Penk 1902 0.78 275.47 1057.59 100.00
139 INT55662 Negative_regulation of Negative_regulation of KNG1 4 0.36 3.45 0.57 100.00
140 INT8534 Localization of Pax3 85 0.59 28.71 82.82 100.00
141 INT27918 Positive_regulation of Klk1c7 6 0.36 2.89 2.84 100.00
142 INT28265 Positive_regulation of Calca 62 0.70 29.1 41.17 100.00
143 INT271461 Positive_regulation of Positive_regulation of Gd 1 0.14 3.87 1.19 100.00
144 INT37076 Negative_regulation of Binding of KNG1 3 0.14 1.77 1.32 100.00
145 INT94196 Negative_regulation of Phosphorylation of MAPK1 60 0.59 31.64 9.16 100.00
146 INT8784 Negative_regulation of Positive_regulation of Calca 40 0.59 14.67 33.49 100.00
147 INT13085 Positive_regulation of ACE 50 0.70 44.2 8.31 100.00
148 INT156305 Regulation of Syt17 1 0.04 0.49 0.71 100.00
149 INT170030 Positive_regulation of Gene_expression of Kcnmb1 1 0.01 1.49 1.48 100.00
150 INT28833 Localization of Bdkrb1 3 0.81 2.17 2.28 100.00
151 INT162358 Positive_regulation of Gene_expression of KRT32 1 0.12 0.57 0.57 100.00
152 INT27920 Regulation of Protein_catabolism of Mbis1 1 0.00 0 0.68 100.00
153 INT112038 Positive_regulation of P2ry2 8 0.45 2.41 4.4 100.00
154 INT9567 Binding of Nts 10 0.44 2.14 5.89 100.00
155 INT87686 Positive_regulation of Gene_expression of Trpv1 101 0.70 72.41 69.15 100.00
156 INT8048 Gene_expression of Nts 45 0.74 8.9 21.84 100.00
157 INT4727 Regulation of TAC1 60 0.47 6.74 32.83 100.00
158 INT121195 Phosphorylation of KCNMA1 5 0.63 0.49 0.6 100.00
159 INT150640 Regulation of Binding of KNG1 3 0.35 1.31 2.2 100.00
160 INT65772 Positive_regulation of Positive_regulation of Bdkrb1 6 0.49 8.34 6.54 100.00
161 INT299996 Positive_regulation of KCNMB1 1 0.01 0.65 0.98 100.00
162 INT7132 Localization of NPPA 53 0.81 19.79 10.86 100.00
163 INT15298 Gene_expression of Efs 10 0.61 0.22 2.48 100.00
164 INT10272 Gene_expression of Il1b 194 0.78 121.02 103.03 100.00
165 INT61300 Negative_regulation of Binding of Bdkrb1 3 0.42 3 3.69 100.00
166 INT8589 Positive_regulation of Positive_regulation of Tacr1 14 0.69 7.85 10.86 100.00
167 INT8837 Positive_regulation of TAC1 59 0.67 21.94 35.97 100.00
168 INT53348 Binding of BDKRB2 7 0.37 2.85 3 100.00
169 INT16359 Positive_regulation of Gene_expression of AGT 30 0.49 28.27 6.14 100.00
170 INT114340 Positive_regulation of Protein_catabolism of KNG1 5 0.07 2.42 0.92 100.00
171 INT104777 Regulation of DES 4 0.38 2.38 1.2 100.00
172 INT83098 Gene_expression of KCNMB1 3 0.11 0.26 0.68 100.00
173 INT126635 Negative_regulation of Alox15 2 0.41 0.67 1.43 100.00
174 INT797 Regulation of Penk 812 0.62 111.13 542.24 100.00
175 INT26451 Gene_expression of KLK1 14 0.75 5.79 1.66 100.00
176 INT23956 Negative_regulation of DES 12 0.42 10.84 1.82 100.00
177 INT162613 Negative_regulation of Syt17 1 0.04 0.19 0.6 100.00
178 INT50 Negative_regulation of Localization of Ren 87 0.59 14.94 30.22 100.00
179 INT99636 Negative_regulation of Localization of Fgf2 4 0.41 1.32 1.97 100.00
180 INT162354 Positive_regulation of Localization of KRT32 1 0.12 0.37 0.46 100.00
181 INT162363 Localization of KRT32 1 0.18 0.37 0.46 100.00
182 INT261682 Positive_regulation of Positive_regulation of PSEN2 1 0.21 0.55 0.33 100.00
183 INT48979 Regulation of Gene_expression of FOS 52 0.61 14.4 25.95 100.00
184 INT120403 Regulation of Phosphorylation of EPHB2 2 0.60 1.92 0.5 100.00
185 INT4141 Binding of Ptger1 19 0.31 2.96 4.83 100.00
186 INT22335 Regulation of Negative_regulation of ACE 10 0.44 7.01 1.77 100.00
187 INT53251 Positive_regulation of Gene_expression of Kng1 2 0.60 0.71 0.58 100.00
188 INT27018 Gene_expression of PTGER1 68 0.75 31.76 20.12 100.00
189 INT114749 Phosphorylation of Syt17 1 0.22 0.96 1.16 100.00
190 INT52714 Regulation of PRKCA 28 0.61 7.73 13.66 100.00
191 INT5010 Gene_expression of Calca 197 0.78 85.76 118.75 100.00
192 INT104027 Negative_regulation of Negative_regulation of MAPK1 6 0.56 2.87 1.35 100.00
193 INT1429 Gene_expression of PDYN 308 0.78 61.33 175.65 100.00
194 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 100.00
195 INT14205 Regulation of KLK1 10 0.60 4.38 1.28 100.00
196 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 100.00
197 INT2140 Regulation of REN 104 0.62 28.24 24.49 100.00
198 INT24326 Gene_expression of Ngf 346 0.78 218.67 184.71 100.00
199 INT87941 Negative_regulation of DRGX 11 0.13 7.14 6.74 100.00
200 INT15136 Regulation of Positive_regulation of Calca 12 0.62 3.02 12.16 100.00
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