P:COX2

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pChart

Pain Term
Category Molecule
Synonyms COX 2, Cyclooxygenase 2
Pain Specific No
Documents 2652
Hot Single Events 200
Hot Interactions 133

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for COX2. They are ordered first by their pain relevance and then by number of times they were reported for COX2. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT77807 Edn1 Positive_regulation of Gene_expression of Ptgs2 1 0.33 0.53 2.1 100.00
2 INT77806 Edn1 Regulation of Gene_expression of Ptgs2 1 0.29 1.24 1.22 100.00
3 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14 100.00
4 INT267123 ROS1 Positive_regulation of Positive_regulation of Nfkb1 1 0.01 1.05 0.31 100.00
5 INT253469 H37 Negative_regulation of Gene_expression of Gopc 1 0.00 1.5 0.31 100.00
6 INT108389 IL1B Positive_regulation of ADAMTS4 1 0.51 1.19 1.24 100.00
7 INT108386 IL1B Positive_regulation of MMP1 3 0.27 1.56 1.28 100.00
8 INT161251 Ptgs2 Regulation of Mapk14 1 0.16 0.82 0.54 100.00
9 INT65986 IL1B Positive_regulation of PTGS2 3 0.32 2.05 1.03 100.00
10 INT311950 FBN1 Positive_regulation of Gene_expression of PGF 1 0.00 0.15 0.26 100.00
11 INT195117 Ptgs2 Positive_regulation of Gene_expression of Il6 1 0.10 3.26 1.16 100.00
12 INT149628 Il1b Regulation of Gene_expression of Ptgs2 1 0.30 0.84 0.84 100.00
13 INT149626 Il1b Regulation of Gene_expression of Tnf 1 0.41 0.83 0.83 100.00
14 INT158068 Positive_regulation of Pparg Positive_regulation of Positive_regulation of PTGS2 1 0.01 0.28 0.76 100.00
15 INT65985 IL1B Positive_regulation of Gene_expression of PTGS2 3 0.23 2.62 0.71 100.00
16 INT139044 AKR1B1 Regulation of Gene_expression of PTGS2 1 0.09 0.37 0.3 100.00
17 INT142450 B4GALNT1 Regulation of Gene_expression of PTGIS 1 0.02 0.24 0.27 100.00
18 INT142447 PTGS2 Regulation of Gene_expression of PTGIS 1 0.30 0.24 0.27 100.00
19 INT139015 STAT1 Negative_regulation of Gene_expression of PTGS2 1 0.01 0.36 0.19 100.00
20 INT79651 PTGS2 Positive_regulation of Phosphorylation of NR3C1 1 0.07 0.1 0.19 100.00
21 INT190772 Il4 Negative_regulation of Gene_expression of Ptger2 1 0.03 1.28 1.49 100.00
22 INT190773 Il4 Negative_regulation of Gene_expression of Ptgs2 1 0.06 1.26 1.45 100.00
23 INT190774 Il4 Negative_regulation of Positive_regulation of Ptgs2 1 0.06 1.26 1.45 100.00
24 INT177457 Il1 Positive_regulation of Gene_expression of Il6 3 0.16 4.47 1.35 100.00
25 INT143426 Positive_regulation of B4GALNT1 Negative_regulation of Gene_expression of Nos2 1 0.00 0.83 0.58 100.00
26 INT254197 Mif Regulation of Ptgs2 1 0.02 1.08 0.55 100.00
27 INT145435 Binding of CPOX and HMOX1 1 0.01 0.42 0.49 100.00
28 INT145433 Binding of CPOX and HMOX2 1 0.01 0.42 0.49 100.00
29 INT145434 Binding of HMOX1 and PTGS2 1 0.02 0.41 0.47 100.00
30 INT145436 Binding of HMOX2 and PTGS2 1 0.02 0.41 0.47 100.00
31 INT157150 Positive_regulation of PTGIR Negative_regulation of Gene_expression of TNF 1 0.12 0.97 0.34 100.00
32 INT143567 Edn1 Regulation of Ptgs2 1 0.26 0.17 0.33 100.00
33 INT294115 IDO1 Positive_regulation of PTGER2 1 0.02 0.36 0.31 100.00
34 INT294117 HGF Positive_regulation of PTGER2 1 0.02 0.36 0.31 100.00
35 INT116594 Negative_regulation of PTGS2 Negative_regulation of Gene_expression of IL6 1 0.22 0.45 0.31 100.00
36 INT114069 Negative_regulation of Agtr2 Positive_regulation of Ptgs2 1 0.08 0.49 0.26 100.00
37 INT107615 IL1B Positive_regulation of PTGES 2 0.55 0.05 0.26 100.00
38 INT335126 Ptgs2 Positive_regulation of Gene_expression of PPARA 1 0.24 0.72 0.25 100.00
39 INT102625 IL6 Regulation of Gene_expression of PTGS2 1 0.11 0.29 0.24 100.00
40 INT102620 PTAFR Regulation of Gene_expression of IL6 1 0.24 0.29 0.24 100.00
41 INT102622 PTAFR Regulation of IL6 1 0.24 0.29 0.24 100.00
42 INT102617 PTAFR Regulation of Gene_expression of PTGS2 1 0.12 0.29 0.24 100.00
43 INT132382 Nos2 Positive_regulation of PTGS2 1 0.02 0.1 0.23 100.00
44 INT112134 Gast Positive_regulation of Gene_expression of Ptgs2 1 0.28 0.19 0.21 100.00
45 INT92580 IGF2 Positive_regulation of Gene_expression of PTGER2 1 0.07 0.43 0.15 100.00
46 INT176621 PTGS2 Regulation of Gene_expression of PTGER2 1 0.00 0.09 0.15 100.00
47 INT92583 IGF2 Positive_regulation of Transcription of PTGER2 1 0.07 0.43 0.15 100.00
48 INT87710 MYB Regulation of PTGS2 1 0.28 0.64 0.15 100.00
49 INT334043 Cdt1 Positive_regulation of Gene_expression of ALPP 1 0.08 0.39 0.05 100.00
50 INT341882 Positive_regulation of Oxtr Positive_regulation of Positive_regulation of Ptgs2 1 0.02 0.11 0.05 100.00
51 INT120574 Binding of Apc and Egfr 1 0.27 1.02 0.05 100.00
52 INT98346 Negative_regulation of Binding of CPOX and PTGS1 1 0.10 2.91 6.54 99.98
53 INT81657 Binding of CPOX and PTGS1 5 0.15 1.9 2.37 99.98
54 INT101320 Negative_regulation of Ptgs1 Positive_regulation of Ptgs2 1 0.03 0.2 0.62 99.94
55 INT78590 Nos2 Positive_regulation of PTGS1 2 0.00 0.85 0.5 99.92
56 INT276228 Nrtim1 Positive_regulation of PPARG 1 0.01 2.18 0.14 99.90
57 INT220193 PTGER2 Regulation of PTGES 1 0.06 0.66 0.41 99.90
58 INT92581 IGF1R Positive_regulation of Gene_expression of PTGER2 1 0.09 0.79 0.24 99.86
59 INT92582 IGF1R Positive_regulation of Transcription of PTGER2 1 0.09 0.43 0.15 99.86
60 INT161250 Trib3 Regulation of Mapk14 1 0.04 0.81 0.54 99.80
61 INT311963 Ifx Negative_regulation of FBN1 1 0.00 0.44 0.5 99.80
62 INT124261 Jun Regulation of Gene_expression of Cpox 1 0.13 0.44 0.32 99.78
63 INT124258 Creb1 Regulation of Gene_expression of Cpox 1 0.17 0.44 0.32 99.78
64 INT168809 Nfkb1 Positive_regulation of Transcription of Trub1 1 0.02 0.44 0.28 99.76
65 INT145015 CREB5 Positive_regulation of GAST Positive_regulation of PTGS2 1 0.06 0.51 0.22 99.76
66 INT112136 Egf Positive_regulation of Gene_expression of Ptgs2 1 0.21 0.19 0.21 99.76
67 INT51051 IL1B Positive_regulation of Localization of IL6 7 0.57 3.79 1.87 99.62
68 INT124078 Binding of Ace and Cpox 1 0.09 0.14 0.24 99.60
69 INT126887 Protein_catabolism of SP4 Negative_regulation of Gene_expression of VEGFA 1 0.15 0.49 0.26 99.56
70 INT103092 Binding of PPARA and ISYNA1 1 0.01 0.45 0.54 99.56
71 INT138321 PPA1 Positive_regulation of Gene_expression of PTGS2 1 0.02 0.09 0.14 99.46
72 INT314200 Positive_regulation of Binding of Nos2 and Tnf 1 0.42 0.34 0.46 99.44
73 INT314201 Binding of Nos2 and Tnf 1 0.31 0.33 0.46 99.44
74 INT126886 Protein_catabolism of SP1 Negative_regulation of Gene_expression of VEGFA 1 0.03 0.49 0.26 99.44
75 INT254200 Mif Regulation of Trp53 1 0.02 0.96 0.52 99.40
76 INT253467 H37 Positive_regulation of Fpr3 1 0.00 1.27 0.13 99.36
77 INT145014 Positive_regulation of GAST Positive_regulation of PTGS2 1 0.31 0.51 0.22 99.34
78 INT62176 Binding of PTGS2 and Ptgs1 2 0.00 0.69 0.79 99.22
79 INT136795 Spp1 Positive_regulation of Chuk 1 0.11 1.54 0.77 99.20
80 INT105849 Il1b Positive_regulation of Positive_regulation of Ptgs1 1 0.07 0.38 0.51 99.18
81 INT108879 Negative_regulation of PTGS2 Positive_regulation of Protein_catabolism of Nfkbia 1 0.00 0.43 0.31 99.08
82 INT145012 GAST Positive_regulation of PTGS2 1 0.42 0.51 0.22 99.06
83 INT253486 H37 Positive_regulation of Gene_expression of Fpr3 1 0.00 1.17 0.13 98.90
84 INT119100 Positive_regulation of F2rl1 Positive_regulation of Positive_regulation of Ptgs1 1 0.03 0.56 0.9 98.88
85 INT81992 IL1A Positive_regulation of Positive_regulation of Tnfsf11 1 0.05 0.27 0.13 98.82
86 INT81983 IL1A Positive_regulation of Positive_regulation of PTGS2 1 0.01 0.27 0.13 98.82
87 INT253475 Ncapg2 Positive_regulation of Gene_expression of Fpr3 1 0.21 3.11 0.47 98.52
88 INT159593 Regulation of Nfkb1 Positive_regulation of Gene_expression of Nos2 1 0.38 0.46 0.74 98.32
89 INT253485 Fpr3 Regulation of Gene_expression of Ptger2 1 0.10 2.87 0.17 98.04
90 INT141113 Sftpa1 Negative_regulation of Sftpa1 Positive_regulation of Ptgs2 1 0.46 0.32 0.14 97.92
91 INT78588 Positive_regulation of Binding of Nfkb1 and Nos2 1 0.01 0.33 0.56 97.84
92 INT141110 Negative_regulation of Sftpa1 Positive_regulation of Mapk1 1 0.47 0.31 0.14 97.64
93 INT141112 Negative_regulation of Sftpa1 Positive_regulation of Ptgs2 1 0.39 0.31 0.14 97.64
94 INT196879 Cpox Negative_regulation of Gene_expression of Tbxa2r 1 0.04 0.8 0.56 97.56
95 INT314199 Mapk14 Regulation of Tnf 1 0.26 0.71 0.67 97.56
96 INT108387 IL1B Positive_regulation of Localization of MMP1 1 0.27 0.3 0.57 96.72
97 INT166788 HRAS Negative_regulation of Phosphorylation of NFKB1 1 0.08 0.5 0.39 96.52
98 INT78587 Binding of Nfkb1 and Nos2 1 0.01 0.33 0.55 96.44
99 INT141109 Sftpa1 Positive_regulation of Mapk1 1 0.77 0.65 0.27 95.04
100 INT141111 Sftpa1 Positive_regulation of Ptgs2 1 0.64 0.3 0.14 95.04
101 INT254210 Binding of Cxcr2 and Ccl2 1 0.08 2.39 1.25 94.24
102 INT60213 Binding of Ptgs1 and Ptgs2 2 0.37 0.5 0.97 94.00
103 INT253476 Ptger2 Negative_regulation of Fpr3 1 0.14 1.22 0.12 92.60
104 INT166792 Binding of CD44 and HRAS 3 0.12 1.49 0.37 90.56
105 INT182126 IRF6 Positive_regulation of Gene_expression of SELE 1 0.03 0.86 0.34 90.16
106 INT144043 IL13 Positive_regulation of PTGES 1 0.32 0.43 0.37 89.60
107 INT144047 IL4 Positive_regulation of PTGES 1 0.29 0.43 0.37 88.80
108 INT340447 Negative_regulation of IRF6 Positive_regulation of RELA 1 0.00 0.87 0.18 88.40
109 INT340448 IRF6 Positive_regulation of RELA 1 0.00 0.86 0.17 88.40
110 INT159837 Trim2 Negative_regulation of Transcription of Fos 1 0.10 1.92 1.22 88.08
111 INT144044 IRF6 Positive_regulation of PTGES 1 0.10 0.43 0.37 86.64
112 INT254216 Mapk14 Positive_regulation of Mapk1 1 0.02 0.87 0.46 86.48
113 INT69163 Tlr4 Positive_regulation of Ptgs1 1 0.02 0.08 0.44 86.24
114 INT166789 HRAS Regulation of Positive_regulation of NFKB1 1 0.05 0.31 0.3 86.20
115 INT343157 ACSL4 Regulation of Gene_expression of ALOX15 1 0.01 0.67 0.07 86.16
116 INT294116 CIITA Regulation of Gene_expression of HLA-E 1 0.05 0.05 0.08 85.96
117 INT254225 Mapk14 Positive_regulation of Mapk8 1 0.02 0.87 0.46 85.84
118 INT254198 Mapk1 Positive_regulation of Mapk8 1 0.01 0.87 0.46 85.84
119 INT118288 EGF Positive_regulation of Phosphorylation of EGFR 9 0.54 3.85 0.9 85.60
120 INT342456 AGT Positive_regulation of Gene_expression of CCL2 1 0.07 0.63 0.25 85.48
121 INT254222 Mapk1 Positive_regulation of Mapk14 1 0.02 0.86 0.46 85.44
122 INT314203 Nos2 Positive_regulation of Gli3 1 0.19 1.27 0.73 85.40
123 INT140264 Tlr4 Positive_regulation of Nfkb1 1 0.00 0.23 0.59 84.68
124 INT140263 Negative_regulation of Tlr4 Positive_regulation of Nfkb1 1 0.00 0.23 0.59 84.68
125 INT254230 Ik Negative_regulation of Gene_expression of TNF 1 0.00 1.29 0.65 84.64
126 INT197112 Binding of IL1B and TP53TG3 1 0.03 1.17 0.31 84.40
127 INT195122 Il1 Positive_regulation of Gene_expression of Gtf3a 1 0.02 1.38 0.5 83.48
128 INT328851 Binding of PTGS2 and ZNF434 1 0.00 0.7 0.14 82.16
129 INT222183 Binding of HDLBP and PLA2G15 1 0.01 0.7 0.57 82.04
130 INT176623 Binding of PTGER2 and NDRG1 1 0.00 0.1 0.16 81.68
131 INT166790 HRAS Negative_regulation of Gene_expression of PTGER1 1 0.01 1.46 0.95 80.64
132 INT166787 CD44 Negative_regulation of Gene_expression of PTGER1 1 0.04 0.15 0.2 80.52
133 INT126385 Ptger2 Positive_regulation of Positive_regulation of Il6 1 0.01 0.07 0.35 80.40
134 INT166791 CD44 Positive_regulation of Gene_expression of PTGER1 1 0.05 0.15 0.2 79.76
135 INT253473 Ncapg2 Positive_regulation of Gene_expression of Gopc 1 0.08 1.26 0.27 79.48
136 INT253482 H37 Positive_regulation of Gene_expression of Gopc 1 0.00 3.99 0.4 79.04
137 INT299041 SPARC Regulation of Gene_expression of NPEPPS 1 0.01 0.83 0.42 78.72
138 INT299040 Binding of COL7A1 and SPARC 1 0.02 0.7 0.42 78.72
139 INT253487 Ncapg2 Positive_regulation of Fpr3 1 0.21 0.73 0.08 78.16
140 INT324525 PGE Positive_regulation of Positive_regulation of Egfr 1 0.41 1.05 0.33 78.12
141 INT324522 PGE Positive_regulation of Phosphorylation of Egfr 1 0.56 1.04 0.33 78.12
142 INT324524 PGE Positive_regulation of Egfr 1 0.38 1.05 0.33 78.12
143 INT324527 PGE Positive_regulation of Egfr Positive_regulation of Phosphorylation of Egfr 1 0.38 1.05 0.33 78.12
144 INT144046 IL13 Negative_regulation of Gene_expression of PTGES 1 0.30 0.48 0.35 76.88
145 INT144045 IFNG Negative_regulation of Gene_expression of PTGES 1 0.63 0.47 0.35 76.88
146 INT144050 IL4 Negative_regulation of Gene_expression of PTGES 1 0.27 0.48 0.35 76.88
147 INT144049 IL10 Negative_regulation of Gene_expression of PTGES 1 0.35 0.47 0.35 76.88
148 INT144048 IRF6 Positive_regulation of Gene_expression of PTGES 1 0.12 0.46 0.35 76.88
149 INT266660 PTGER2 Positive_regulation of Gene_expression of MMP9 1 0.06 0.08 0.12 76.64
150 INT94262 IL1B Positive_regulation of Localization of PTGER2 1 0.22 0.8 0.49 76.08
151 INT308551 Binding of HP and VPS45 1 0.04 0.44 0.15 75.96
152 INT73332 IL1B Positive_regulation of Transcription of PTGS2 1 0.44 0.54 0.18 75.00
153 INT73331 PTAFR Positive_regulation of Transcription of PTGS2 1 0.13 0.54 0.18 75.00
154 INT298196 EGFR Positive_regulation of PIK3CD 1 0.04 0.65 0.18 74.48
155 INT298192 EGFR Positive_regulation of AKT1 1 0.10 0.65 0.18 74.48
156 INT196886 Ly6 Positive_regulation of Binding of Ly6 and Prkca 1 0.00 0.18 0.25 73.52
157 INT196880 Binding of Ly6 and Prkca 1 0.01 0.18 0.25 73.52
158 INT339072 Eae1 Positive_regulation of Gene_expression of Nos2 1 0.02 3.76 0.59 72.40
159 INT196881 Ly6 Positive_regulation of Prkca 2 0.01 0.25 0.42 72.24
160 INT108332 EGF Positive_regulation of Phosphorylation of MAPK1 5 0.48 1.85 0.45 70.92
161 INT226337 Binding of IL10 and IL10RA 2 0.24 2.51 0.85 69.64
162 INT314208 Trap1 Positive_regulation of Mapk14 1 0.10 0.66 0.57 67.84
163 INT321826 Stat3 Positive_regulation of Localization of CSF2 1 0.02 0 0.12 62.44
164 INT171261 IL8 Positive_regulation of MMP1 1 0.04 0.05 0.07 62.36
165 INT171275 IL8 Positive_regulation of PTGER2 1 0.01 0.05 0.07 62.36
166 INT179502 Binding of Cd14 and Tlr4 29 0.39 13.77 5.73 61.28
167 INT231534 Binding of JAK1 and SOAT1 1 0.01 0.6 0.64 61.00
168 INT231535 Binding of JAK2 and SOAT1 1 0.01 0.3 0.35 61.00
169 INT314197 Mapk14 Positive_regulation of Positive_regulation of Tnf 1 0.48 1.16 0.61 59.16
170 INT326126 Binding of S100A1 and TP53 1 0.04 1.34 0.09 59.00
171 INT142286 Binding of PLG and Plat 2 0.52 0.7 0.31 58.44
172 INT197111 Binding of IL1B and MCF2 1 0.02 2.12 1.4 57.88
173 INT197115 Binding of MCF2 and RETNLB 1 0.00 1.06 0.7 57.88
174 INT324523 Tlr4 Regulation of Gene_expression of PGE 1 0.23 1.98 0.51 57.20
175 INT197113 RETNLB Regulation of IL1B 1 0.00 1.27 0.44 56.80
176 INT179503 Cd14 Regulation of Positive_regulation of Tlr4 1 0.38 0.58 0.52 55.84
177 INT229913 Positive_regulation of Ntsr1 Positive_regulation of Gene_expression of Egr1 1 0.12 1.33 1.11 54.56
178 INT343164 ACSL4 Regulation of Positive_regulation of ALOX15 1 0.01 1.08 0.03 54.28
179 INT355583 Binding of EGFR and ANGPTL4 1 0.12 2.14 0.05 52.40
180 INT355589 Binding of EGFR and LTBP1 1 0.11 2.15 0.05 52.40
181 INT355586 Binding of LTBP1 and ANGPTL4 1 0.10 2.15 0.05 52.20
182 INT196883 Prkca Regulation of P2rx1 1 0.05 0.45 0.31 50.48
183 INT240441 Ltb4r1 Positive_regulation of PPARA 1 0.03 1.01 0.47 50.00
184 INT240442 Binding of PPARA and Ltb4r1 1 0.02 0.94 0.46 50.00
185 INT240434 PPARA Negative_regulation of Gene_expression of CPOX 1 0.03 0.64 0.33 50.00
186 INT240435 JUN Positive_regulation of Gene_expression of CPOX 1 0.01 0.81 0.18 50.00
187 INT166069 ZNF398 Regulation of VEGFA 1 0.01 0.07 0 50.00
188 INT79649 RIMS3 Regulation of Positive_regulation of ITGAL 1 0.00 0 0 50.00
189 INT79644 CTNNBL1 Positive_regulation of Binding of GSR 1 0.08 0 0 50.00
190 INT79652 RIMS3 Regulation of GSR 1 0.03 0 0 50.00
191 INT79645 RIMS3 Positive_regulation of Phosphorylation of GSR 1 0.04 0 0 50.00
192 INT79648 RIMS3 Positive_regulation of Phosphorylation of CTNNBL1 1 0.01 0 0 50.00
193 INT79650 CTNNBL1 Regulation of GSR 1 0.07 0 0 50.00
194 INT79647 RIMS3 Positive_regulation of Binding of GSR 1 0.04 0 0 50.00
195 INT166070 PTGS2 Regulation of VEGFA 1 0.29 0.06 0 50.00
196 INT253481 Ptger3 Negative_regulation of Rtcd1 1 0.00 0.29 0 49.72
197 INT339693 HMGCR Positive_regulation of SREBF2 1 0.05 0.54 0 49.12
198 INT339709 HMGCR Positive_regulation of Gene_expression of SREBF2 1 0.05 0.54 0 49.12
199 INT339699 LDLR Positive_regulation of SREBF2 1 0.08 1.08 0 49.12
200 INT339694 LDLR Positive_regulation of Gene_expression of SREBF2 1 0.08 1.08 0 49.12

Single Events

The table below shows the top 200 pain related interactions that have been reported for COX2. They are ordered first by their pain relevance and then by number of times they were reported in COX2. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85 100.00
2 INT73625 Gene_expression of PPARG 108 0.78 104.85 21.42 100.00
3 INT50674 Gene_expression of PTGS2 459 0.78 253.33 118.51 100.00
4 INT53083 Gene_expression of Ptgs2 153 0.78 90.04 50.39 100.00
5 INT52611 Negative_regulation of Ptgs2 142 0.59 66.31 52.71 100.00
6 INT15613 Negative_regulation of Ptgs2 160 0.59 71.08 65.08 100.00
7 INT39153 Positive_regulation of PTGS2 182 0.70 96.16 60.6 100.00
8 INT2391 Negative_regulation of PTGS1 501 0.59 207.62 205.6 100.00
9 INT50058 Negative_regulation of Cpox 907 0.58 426.28 428.29 100.00
10 INT6580 Negative_regulation of Ptgs1 929 0.59 381.53 376.26 100.00
11 INT55135 Positive_regulation of Gene_expression of PTGS2 137 0.70 80.32 38.46 100.00
12 INT49441 Negative_regulation of Cpox 494 0.59 303.22 177.46 100.00
13 INT52690 Positive_regulation of Ptgs2 65 0.68 39.51 30.02 100.00
14 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 100.00
15 INT8413 Gene_expression of Ptgs1 248 0.78 110.17 108.58 100.00
16 INT66280 Gene_expression of Nos2 534 0.78 330.78 157.07 100.00
17 INT52692 Gene_expression of Ptgs2 160 0.78 85.06 55.73 100.00
18 INT22764 Localization of Ptger2 81 0.64 24.38 26.77 100.00
19 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 100.00
20 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08 100.00
21 INT52696 Positive_regulation of Ptgs2 48 0.70 27.65 14.44 100.00
22 INT51921 Gene_expression of Cpox 501 0.73 229.81 157.81 100.00
23 INT1760 Gene_expression of PTGER2 524 0.57 226.94 96.4 100.00
24 INT48953 Positive_regulation of Nos2 486 0.70 239.85 131.87 100.00
25 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 100.00
26 INT3950 Gene_expression of Ptger2 293 0.77 122.28 62.42 100.00
27 INT17848 Binding of PTGS2 70 0.46 32.1 20.6 100.00
28 INT9196 Gene_expression of PTGS1 215 0.77 96.99 60.5 100.00
29 INT115385 Negative_regulation of Ppara 154 0.58 129.05 27.58 100.00
30 INT79692 Negative_regulation of PPARG 24 0.59 16 4.31 100.00
31 INT50490 Regulation of PTGS2 80 0.48 39.51 25.85 100.00
32 INT64636 Positive_regulation of Gene_expression of Nos2 242 0.70 147.52 79.53 100.00
33 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 100.00
34 INT63419 Gene_expression of PTGES 109 0.77 40.83 23.67 100.00
35 INT50670 Gene_expression of CPOX 763 0.76 442.13 195.02 100.00
36 INT55944 Positive_regulation of Cpox 214 0.57 105.14 81.4 100.00
37 INT69992 Negative_regulation of Hmox2 93 0.50 49.01 44.07 100.00
38 INT48952 Negative_regulation of Nos2 204 0.59 101.73 53.15 100.00
39 INT53082 Positive_regulation of Gene_expression of Ptgs2 47 0.64 25.39 11.39 100.00
40 INT52695 Regulation of Ptgs2 20 0.42 8.72 5.71 100.00
41 INT183207 Negative_regulation of USE1 14 0.18 10.97 4 100.00
42 INT59080 Negative_regulation of Gene_expression of PTGS2 55 0.58 22.92 12.39 100.00
43 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1 100.00
44 INT5759 Positive_regulation of Ptgs1 127 0.69 53.45 53.04 100.00
45 INT35975 Regulation of Cpox 109 0.39 57.88 49.69 100.00
46 INT52689 Regulation of Ptgs2 27 0.60 12.76 10.6 100.00
47 INT52693 Positive_regulation of Gene_expression of Ptgs2 57 0.70 25.51 21.18 100.00
48 INT940 Negative_regulation of Ptgs1 219 0.59 104.34 95.97 100.00
49 INT2389 Regulation of PTGS1 86 0.61 31.23 28.95 100.00
50 INT77435 Positive_regulation of Nos2 343 0.70 208.49 91.43 100.00
51 INT110020 Gene_expression of Mapk14 142 0.77 72.33 30.08 100.00
52 INT94615 Localization of Ptger4 5 0.28 0.35 2.13 100.00
53 INT103096 Regulation of PPARA 113 0.60 62.47 14.57 100.00
54 INT53081 Negative_regulation of Gene_expression of Ptgs2 29 0.59 15.83 10.39 100.00
55 INT93663 Positive_regulation of MMP1 72 0.67 33.38 19.86 100.00
56 INT45840 Positive_regulation of Gene_expression of Ptgs1 35 0.50 16.07 20.49 100.00
57 INT88059 Positive_regulation of Ptger4 9 0.69 1.41 4.4 100.00
58 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9 100.00
59 INT69321 Regulation of Gene_expression of PTGS2 27 0.61 13.27 9.53 100.00
60 INT8465 Regulation of Ptgs1 100 0.57 36.03 44.41 100.00
61 INT101517 Negative_regulation of PPARA 168 0.57 112.24 21.41 100.00
62 INT79689 Regulation of PPARG 10 0.62 8.04 1.07 100.00
63 INT52531 Gene_expression of Nfkb1 153 0.75 82.84 42.9 100.00
64 INT94953 Negative_regulation of Mapk14 156 0.59 104.77 91.51 100.00
65 INT61953 Transcription of Nos2 101 0.72 46.64 25.49 100.00
66 INT69743 Gene_expression of Hmox2 36 0.78 20.77 14.26 100.00
67 INT77805 Regulation of Gene_expression of Ptgs2 6 0.51 2.7 1.92 100.00
68 INT55335 Binding of Cpox 49 0.34 15.48 18.46 100.00
69 INT92837 Negative_regulation of Gene_expression of Nos2 116 0.59 59.67 31.82 100.00
70 INT36798 Gene_expression of Mki67 178 0.77 132 8.24 100.00
71 INT73626 Positive_regulation of Gene_expression of PPARG 22 0.70 18.82 4.4 100.00
72 INT19191 Negative_regulation of Localization of IL1B 35 0.58 15.19 13.63 100.00
73 INT64163 Negative_regulation of Gene_expression of Jun 13 0.58 3.86 4.03 100.00
74 INT666 Gene_expression of Jun 124 0.78 54.61 33.67 100.00
75 INT53200 Binding of Ptgs2 11 0.48 5.08 3.54 100.00
76 INT69876 Negative_regulation of Nfkb1 147 0.58 89.81 55.5 100.00
77 INT21503 Binding of Ptgs1 45 0.48 15.6 22.29 100.00
78 INT85943 Negative_regulation of Nos2 161 0.59 108.56 42.65 100.00
79 INT73340 Negative_regulation of Faah 134 0.59 38.67 85.03 100.00
80 INT78958 Regulation of Negative_regulation of Ptgs2 6 0.42 2.61 2.3 100.00
81 INT20280 Positive_regulation of Esr1 32 0.69 18.37 5.69 100.00
82 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71 100.00
83 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1 100.00
84 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 100.00
85 INT112530 Localization of Ptgs2 13 0.70 7.77 5.86 100.00
86 INT115773 Negative_regulation of Localization of Ptgs2 6 0.43 2.99 3.81 100.00
87 INT73309 Regulation of Negative_regulation of PTGS2 14 0.44 9.55 4.5 100.00
88 INT65055 Negative_regulation of Nfkb1 83 0.58 44.85 34.94 100.00
89 INT1763 Regulation of Gene_expression of PTGER2 43 0.36 23.98 10.95 100.00
90 INT116605 Binding of Nos2 28 0.37 16.88 8.18 100.00
91 INT64171 Regulation of CPOX 109 0.36 55.36 32.96 100.00
92 INT35029 Positive_regulation of Gene_expression of Ptger2 66 0.43 26.37 13.99 100.00
93 INT59079 Transcription of PTGS2 30 0.72 14.21 6.52 100.00
94 INT54571 Positive_regulation of NFKB1 263 0.70 138.99 87.32 100.00
95 INT178306 Negative_regulation of Gene_expression of Gopc 71 0.37 26.43 9.74 100.00
96 INT89854 Regulation of Nos2 49 0.61 42.58 24.1 100.00
97 INT61258 Transcription of Nfkb1 24 0.67 10.89 6.32 100.00
98 INT120901 Positive_regulation of Gene_expression of Il13 36 0.57 31.63 13.36 100.00
99 INT134145 Negative_regulation of Gene_expression of PTGES 11 0.51 5.32 2.73 100.00
100 INT104364 Localization of Hmox2 3 0.03 2.59 2.18 100.00
101 INT181194 Regulation of Gene_expression of PPARA 31 0.44 21.27 5.96 100.00
102 INT76405 Positive_regulation of Hmox2 21 0.43 12.77 8.99 100.00
103 INT17390 Regulation of GNAI1 5 0.04 3.58 2.03 100.00
104 INT67656 Positive_regulation of Positive_regulation of PTGS2 12 0.46 4.83 6.17 100.00
105 INT79060 Gene_expression of NOS2 116 0.78 69.25 34.84 100.00
106 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 100.00
107 INT16814 Negative_regulation of COX5A 74 0.57 33.72 28.63 100.00
108 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 100.00
109 INT52688 Transcription of Ptgs2 16 0.69 8.31 7.52 100.00
110 INT173159 Localization of PPARA 96 0.74 64.55 10.26 100.00
111 INT64915 Regulation of Negative_regulation of PTGS1 4 0.20 1.81 1.76 100.00
112 INT7180 Negative_regulation of Trib3 180 0.51 68.48 88.01 100.00
113 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 100.00
114 INT9197 Binding of PTGS1 44 0.48 18.48 16.26 100.00
115 INT37896 Positive_regulation of Gene_expression of PTGS1 37 0.67 17.28 9.27 100.00
116 INT127176 Transcription of Ptgs2 8 0.58 4.68 2.58 100.00
117 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58 100.00
118 INT126094 Negative_regulation of Localization of Hmox2 2 0.02 1.63 1.69 100.00
119 INT52616 Negative_regulation of Positive_regulation of PTGS2 13 0.43 4.95 4.13 100.00
120 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 100.00
121 INT191342 Positive_regulation of Gene_expression of IDO1 4 0.36 3.5 1.75 100.00
122 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 100.00
123 INT68505 Positive_regulation of Negative_regulation of PTGS2 8 0.49 2.26 2.76 100.00
124 INT79691 Regulation of Gene_expression of PPARG 10 0.50 10.44 1.62 100.00
125 INT64917 Regulation of DHRS9 2 0.28 0.25 0.88 100.00
126 INT50672 Positive_regulation of CPOX 205 0.44 125.93 60.06 100.00
127 INT100142 Negative_regulation of Localization of PTGS1 2 0.35 1.71 0.91 100.00
128 INT20457 Regulation of Ptgs1 23 0.48 11.63 11.56 100.00
129 INT50491 Regulation of Gene_expression of PTGS1 17 0.47 6 5.4 100.00
130 INT95675 Negative_regulation of HPGD 2 0.57 0.6 0.92 100.00
131 INT68681 Transcription of VEGFA 132 0.71 80.47 17.03 100.00
132 INT163603 Transcription of CIITA 2 0.56 0.16 0.87 100.00
133 INT294145 Negative_regulation of Transcription of CIITA 1 0.35 0.08 0.17 100.00
134 INT191161 Gene_expression of CIITA 4 0.55 4.35 0.17 100.00
135 INT52694 Negative_regulation of Positive_regulation of Ptgs2 9 0.43 4.72 3.11 100.00
136 INT62813 Negative_regulation of ZNF398 12 0.09 6.2 4.49 100.00
137 INT43721 Gene_expression of Vegfa 49 0.77 36.18 6.63 100.00
138 INT79690 Negative_regulation of Gene_expression of PPARG 10 0.59 10.48 1.55 100.00
139 INT67611 Positive_regulation of Pparg 39 0.69 18.33 13.23 100.00
140 INT78955 Regulation of Gene_expression of Ptgs2 12 0.62 7.22 6.02 100.00
141 INT39256 Localization of PTGS1 17 0.74 6.62 5.1 100.00
142 INT248470 Gene_expression of Ighmbp2 5 0.75 3.32 0.68 100.00
143 INT11729 Regulation of IGF1 71 0.61 44.58 9.71 100.00
144 INT69742 Positive_regulation of Gene_expression of Hmox2 12 0.69 8.29 8.08 100.00
145 INT20234 Regulation of Gene_expression of Ptgs1 11 0.44 6.55 7.72 100.00
146 INT70505 Positive_regulation of Positive_regulation of Ptgs2 4 0.49 2.22 1.08 100.00
147 INT99326 Negative_regulation of Pdha1 2 0.42 0.85 0.84 100.00
148 INT12992 Negative_regulation of Gene_expression of Ptgs1 33 0.42 20.47 11.77 100.00
149 INT55170 Gene_expression of NFKB1 97 0.77 52.75 23.04 100.00
150 INT61293 Transcription of Fn1 3 0.40 2.68 0.36 100.00
151 INT247566 Transcription of Nt5e 3 0.17 1.73 0.19 100.00
152 INT115733 Positive_regulation of Negative_regulation of Faah 8 0.50 3.62 7.26 100.00
153 INT65536 Negative_regulation of Positive_regulation of Nfkb1 77 0.59 38.86 33.33 100.00
154 INT108780 Positive_regulation of Gene_expression of Ptger2 94 0.49 59.71 16.22 100.00
155 INT5307 Regulation of Tnf 87 0.62 78.71 43.4 100.00
156 INT11560 Positive_regulation of CASP3 236 0.70 184.33 39.38 100.00
157 INT160264 Localization of Fn1 10 0.40 3.95 1.51 100.00
158 INT52691 Positive_regulation of Transcription of Ptgs2 5 0.44 3 1.9 100.00
159 INT94036 Negative_regulation of Transcription of Ptgs2 1 0.30 0.52 0.43 100.00
160 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 100.00
161 INT138895 Positive_regulation of Negative_regulation of Hmox2 2 0.01 1.23 1.53 100.00
162 INT34594 Negative_regulation of Gene_expression of ALPP 12 0.50 5.04 1.41 100.00
163 INT20374 Gene_expression of Il4 515 0.76 306.15 114.12 100.00
164 INT100939 Gene_expression of Il13 176 0.73 125.1 43.38 100.00
165 INT50673 Positive_regulation of Gene_expression of CPOX 156 0.54 97.31 37.03 100.00
166 INT20380 Gene_expression of Il5 172 0.78 104.75 34.78 100.00
167 INT54302 Positive_regulation of Gene_expression of Il4 126 0.68 86.18 30.75 100.00
168 INT74286 Regulation of Il10 42 0.44 28.06 19.44 100.00
169 INT38971 Positive_regulation of Gene_expression of Gtf3a 27 0.60 18.25 7.77 100.00
170 INT126984 Positive_regulation of Gene_expression of Il5 29 0.69 20.61 6.72 100.00
171 INT6956 Gene_expression of PTGIS 29 0.76 12.1 3.8 100.00
172 INT66212 Negative_regulation of Localization of RELA 13 0.57 2.48 3.09 100.00
173 INT69991 Negative_regulation of Gene_expression of Hmox2 3 0.04 2.05 2.51 100.00
174 INT133194 Negative_regulation of TERT 23 0.48 4.01 2.45 100.00
175 INT86823 Regulation of Transcription of PTGS2 3 0.19 1.48 1.4 100.00
176 INT101026 Positive_regulation of Negative_regulation of Ptgs2 2 0.35 1.01 1.23 100.00
177 INT130198 Negative_regulation of Binding of PTGS1 3 0.34 2.6 1.16 100.00
178 INT149624 Regulation of Transcription of Ptgs2 1 0.16 0.84 0.84 100.00
179 INT88718 Negative_regulation of Erbb2 11 0.58 12.98 0.84 100.00
180 INT260148 Negative_regulation of Gene_expression of TGFBR2 3 0.38 3.71 0.1 100.00
181 INT108394 Positive_regulation of ADAMTS4 5 0.49 1.65 1.78 100.00
182 INT89603 Regulation of Negative_regulation of Cpox 11 0.30 10.59 6.28 100.00
183 INT10274 Positive_regulation of Il1b 123 0.70 79.76 73.56 100.00
184 INT53476 Positive_regulation of Localization of Ptgs1 6 0.49 2.88 2.35 100.00
185 INT128128 Negative_regulation of Cox4i2 1 0.42 0.2 0.88 100.00
186 INT79062 Gene_expression of B4GALNT1 42 0.14 18.89 6.98 100.00
187 INT74944 Positive_regulation of Gene_expression of HGF 31 0.70 17.69 6.68 100.00
188 INT17915 Gene_expression of Insr 141 0.75 47.45 48.59 100.00
189 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 100.00
190 INT88128 Positive_regulation of Localization of HGF 7 0.45 2.74 0.17 100.00
191 INT112648 Positive_regulation of Fn1 19 0.49 13.73 1.66 100.00
192 INT48959 Positive_regulation of Positive_regulation of Prkcg 52 0.70 16.47 36.49 100.00
193 INT11318 Gene_expression of Gtf3a 274 0.52 183.82 60.89 100.00
194 INT8713 Regulation of Tac1 56 0.60 25.29 45.94 100.00
195 INT267677 Negative_regulation of COX2 1 0.42 0.92 1.66 100.00
196 INT12991 Negative_regulation of Gene_expression of PTGS1 28 0.41 13.39 8.9 100.00
197 INT24902 Gene_expression of SP1 17 0.71 8.11 2.58 100.00
198 INT28123 Positive_regulation of Gene_expression of MSC 17 0.43 4.02 1.54 100.00
199 INT28952 Negative_regulation of Gene_expression of IGF1 75 0.58 41.11 12.32 100.00
200 INT9381 Positive_regulation of TRPV1 523 0.70 187.4 276.05 100.00
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