P:Causalgia

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pChart

Pain Term
Category Disorder
Synonyms None
Pain Specific Yes
Documents 430
Hot Single Events 13
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Causalgia. They are ordered first by their pain relevance and then by number of times they were reported for Causalgia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT98117 Gdnf Regulation of SCN11A 1 0.05 0.39 0.5 50.40
2 INT98116 Gdnf Regulation of SCN10A 1 0.03 0.39 0.5 50.40
3 INT98119 Gdnf Regulation of SCN10A 1 0.01 0.34 0.45 49.92
4 INT98118 Gdnf Regulation of SCN11A 1 0.01 0.34 0.45 49.92
5 INT98121 Ngf Regulation of SCN11A 1 0.07 0.29 0.39 46.80
6 INT98120 Ngf Regulation of SCN10A 1 0.04 0.29 0.39 46.80
7 INT335405 Binding of Arntl and Npas2 1 0.28 1.82 1.61 5.00
8 INT326194 Bdnf Regulation of Slc12a5 1 0.05 0.85 1.35 5.00
9 INT335401 Hgf Positive_regulation of Ngf 1 0.30 1.13 1.04 5.00
10 INT335404 Binding of Arntl and Hspg2 1 0.06 0.93 0.82 5.00
11 INT335403 Binding of Hspg2 and Npas2 1 0.04 0.93 0.82 5.00
12 INT326193 Bdnf Positive_regulation of Car2 2 0.14 0.11 0.62 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Causalgia. They are ordered first by their pain relevance and then by number of times they were reported in Causalgia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT15674 Positive_regulation of Gene_expression of Tac1 17 0.68 4.97 6.56 99.16
2 INT98111 Negative_regulation of Gdnf 12 0.59 10.85 9.29 98.92
3 INT98112 Positive_regulation of Negative_regulation of Gdnf 1 0.05 0.44 0.57 98.92
4 INT11773 Gene_expression of Tac1 56 0.77 10 25.72 98.64
5 INT5680 Gene_expression of Ngf 530 0.78 264.29 310.56 95.64
6 INT16254 Positive_regulation of Gene_expression of Ngf 144 0.70 80.61 82.08 95.64
7 INT100965 Positive_regulation of Nav1 85 0.70 37.74 75.35 94.16
8 INT19086 Negative_regulation of COL1A1 32 0.38 16.77 5.98 92.88
9 INT109297 Negative_regulation of WSN 3 0.05 2.13 1.31 90.92
10 INT8837 Positive_regulation of TAC1 59 0.67 21.94 35.97 90.48
11 INT21940 Positive_regulation of CALR 15 0.40 17.42 0.95 89.76
12 INT16256 Regulation of Ntf3 15 0.49 9.75 13.07 89.12
13 INT39518 Negative_regulation of HBN1 66 0.09 37.54 2.58 83.88
14 INT97368 Negative_regulation of Nav1 62 0.59 41.56 60.27 76.68
15 INT141841 Negative_regulation of Transcription of Nav1 3 0.43 3.15 4.38 76.68
16 INT44642 Positive_regulation of Positive_regulation of T2 1 0.11 1.67 0.08 76.60
17 INT117675 Transcription of Nav1 46 0.72 30.23 44.01 76.16
18 INT44643 Positive_regulation of T2 2 0.11 1.65 0.07 74.92
19 INT15276 Binding of Tac1 6 0.36 0.56 3.16 73.92
20 INT53068 Negative_regulation of Binding of Tac1 1 0.42 0.47 0.36 73.92
21 INT12359 Negative_regulation of Tac1 26 0.58 8.16 6.89 73.04
22 INT21941 Regulation of CALR 7 0.53 3.88 1.96 65.04
23 INT145971 Localization of Nav1 20 0.81 10.3 18.11 62.92
24 INT266565 Positive_regulation of Localization of Nav1 1 0.36 1.24 0.89 62.92
25 INT11980 Positive_regulation of Tac1 27 0.69 6.17 14.5 60.80
26 INT49139 Positive_regulation of Positive_regulation of Tac1 4 0.68 1.74 2.24 60.80
27 INT113925 Localization of Bdnf 59 0.79 24.03 22.76 55.76
28 INT97367 Gene_expression of Nav1 243 0.78 132.97 286.66 54.52
29 INT81229 Binding of COL1A1 24 0.35 12.07 3.3 53.00
30 INT12358 Regulation of Gene_expression of Tac1 17 0.60 3.34 8.84 52.24
31 INT104986 Positive_regulation of CLS 3 0.40 0.65 0.41 50.00
32 INT146349 Gene_expression of CLS 2 0.57 2.93 0 50.00
33 INT66040 Positive_regulation of Bdnf 114 0.69 67.67 51.81 37.36
34 INT7697 Positive_regulation of Adra1a 22 0.68 2.3 9.16 31.92
35 INT17561 Localization of Car2 303 0.79 60.95 44.52 29.12
36 INT74051 Negative_regulation of Localization of Car2 27 0.38 9.58 5.1 29.12
37 INT97366 Regulation of Nav1 38 0.62 23.63 38.17 25.52
38 INT4894 Transcription of Ppt1 34 0.67 5.93 21.06 25.00
39 INT11979 Transcription of Tac4 42 0.52 4.48 20.95 25.00
40 INT53069 Regulation of Transcription of Tac4 4 0.23 0.49 2.36 25.00
41 INT4889 Regulation of Transcription of Ppt1 3 0.35 0.89 1.34 25.00
42 INT92669 Gene_expression of Bdnf 309 0.78 178.26 116.68 10.08
43 INT334332 Protein_catabolism of SPARCL1 1 0.01 1.65 0.15 7.12
44 INT2649 Regulation of Calca 433 0.62 146.05 330.95 5.00
45 INT6665 Gene_expression of FOS 520 0.77 165.31 217.66 5.00
46 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02 5.00
47 INT64201 Negative_regulation of Trpv1 203 0.59 79.18 119.75 5.00
48 INT170025 Gene_expression of Fig4 588 0.67 183.27 113.32 5.00
49 INT82878 Gene_expression of Ccl2 201 0.78 164.95 101.35 5.00
50 INT17459 Positive_regulation of Gene_expression of FOS 182 0.67 53.45 96.38 5.00
51 INT38731 Localization of Trpv1 138 0.81 52.73 90.49 5.00
52 INT171145 Positive_regulation of Fig4 274 0.59 93.55 69.81 5.00
53 INT55224 Gene_expression of DRGX 99 0.31 67.55 67.63 5.00
54 INT6623 Gene_expression of NA 231 0.78 45.78 59.36 5.00
55 INT170646 Negative_regulation of Fig4 213 0.37 81.29 46.92 5.00
56 INT82883 Positive_regulation of Ccl2 105 0.69 84.96 42.27 5.00
57 INT84170 Positive_regulation of Gene_expression of Ccl2 58 0.69 48.79 32.43 5.00
58 INT72252 Gene_expression of Kcnma1 63 0.64 20.47 29.56 5.00
59 INT82882 Localization of Ccl2 61 0.80 41.96 28 5.00
60 INT177581 Regulation of Fig4 113 0.41 39.26 27.75 5.00
61 INT115909 Positive_regulation of Gene_expression of Nav1 25 0.70 16.58 27.63 5.00
62 INT14690 Localization of CSF2 124 0.80 85.17 27.26 5.00
63 INT64076 Positive_regulation of Kcnma1 47 0.40 11.52 24.19 5.00
64 INT117674 Regulation of Gene_expression of Nav1 16 0.62 11.5 22.01 5.00
65 INT11157 Binding of EGF 88 0.48 53.73 21.25 5.00
66 INT163479 Binding of Bdnf 36 0.48 25.77 14.83 5.00
67 INT58852 Positive_regulation of Enc1 20 0.49 7.51 13.25 5.00
68 INT74838 Positive_regulation of Sorbs1 18 0.34 6.93 12.63 5.00
69 INT158124 Gene_expression of COL5A2 136 0.69 72.3 12.44 5.00
70 INT118755 Gene_expression of Per2 12 0.68 2.81 11.41 5.00
71 INT37541 Gene_expression of SPP1 113 0.77 68.54 11.35 5.00
72 INT14334 Negative_regulation of Il2 31 0.58 18.63 11.08 5.00
73 INT113317 Regulation of Cnr2 17 0.52 10.27 10.68 5.00
74 INT94199 Regulation of DRGX 9 0.07 8.31 10.39 5.00
75 INT110633 Binding of Nav1 15 0.42 4.34 9.38 5.00
76 INT1925 Gene_expression of PLAT 47 0.75 34.76 7.88 5.00
77 INT117676 Positive_regulation of Transcription of Nav1 8 0.53 4.37 7.75 5.00
78 INT121419 Localization of Cnr2 11 0.80 4.98 7.14 5.00
79 INT95117 Gene_expression of PDGFA 71 0.71 51.17 6.9 5.00
80 INT85145 Negative_regulation of Cnr2 10 0.44 4.1 6.75 5.00
81 INT87941 Negative_regulation of DRGX 11 0.13 7.14 6.74 5.00
82 INT23465 Gene_expression of S100b 31 0.76 15.09 6.2 5.00
83 INT142690 Positive_regulation of Gene_expression of DRGX 10 0.23 8.54 5.69 5.00
84 INT174851 Positive_regulation of COL5A2 46 0.54 12.73 5.48 5.00
85 INT106555 Binding of Ntrk2 15 0.48 6.31 5.05 5.00
86 INT146091 Negative_regulation of IFNAR1 6 0.25 9.12 4.86 5.00
87 INT72538 Negative_regulation of Sorbs1 7 0.59 4.49 4.61 5.00
88 INT71716 Binding of Hbegf 21 0.28 6.54 4.51 5.00
89 INT19965 Positive_regulation of COL1A1 23 0.45 14.49 4.38 5.00
90 INT153194 Positive_regulation of Positive_regulation of Nav1 5 0.50 3.44 4.24 5.00
91 INT49191 Gene_expression of IFNAR1 14 0.41 9.96 3.84 5.00
92 INT82876 Regulation of IFNAR1 6 0.26 6.69 3.73 5.00
93 INT173751 Transcription of Fig4 31 0.46 8.28 3.7 5.00
94 INT14947 Localization of SPARCL1 7 0.46 11.97 3.6 5.00
95 INT41428 Binding of Vom2r2 4 0.32 1.26 3.35 5.00
96 INT22375 Localization of PDGFA 21 0.75 15.46 3.25 5.00
97 INT112640 Positive_regulation of Negative_regulation of Nav1 3 0.50 1.26 2.98 5.00
98 INT165590 Negative_regulation of Slc12a5 5 0.43 2.62 2.96 5.00
99 INT259760 Localization of Fbn2 5 0.05 5.55 2.85 5.00
100 INT133144 Localization of Mtpn 18 0.24 7.88 2.77 5.00
101 INT91013 Binding of IFNAR1 9 0.46 8.7 2.74 5.00
102 INT163962 Regulation of Transcription of Nav1 2 0.35 3.25 2.63 5.00
103 INT67318 Positive_regulation of Hgf 13 0.69 5.47 2.6 5.00
104 INT259762 Positive_regulation of Fbn2 4 0.05 6.74 2.55 5.00
105 INT158123 Negative_regulation of Gene_expression of COL5A2 19 0.46 15.27 2.23 5.00
106 INT85878 Negative_regulation of Il12a 4 0.58 2.88 2.21 5.00
107 INT266570 Positive_regulation of Binding of Nav1 3 0.44 1.45 2.2 5.00
108 INT87497 Positive_regulation of Cadps 2 0.22 1.77 2.19 5.00
109 INT75939 Positive_regulation of SPARCL1 6 0.28 8.74 2.11 5.00
110 INT335387 Gene_expression of Srd5a2 1 0.50 2.03 2.04 5.00
111 INT48074 Negative_regulation of Cadps 3 0.34 0.74 1.57 5.00
112 INT125767 Positive_regulation of Gene_expression of S100b 6 0.49 4.08 1.52 5.00
113 INT326192 Negative_regulation of Binding of Ntrk2 1 0.10 1 1.47 5.00
114 INT335363 Negative_regulation of Negative_regulation of Nmur2 1 0.18 2.31 1.44 5.00
115 INT104250 Positive_regulation of Gene_expression of SPP1 17 0.69 13.22 1.44 5.00
116 INT290803 Binding of Arntl 10 0.37 1.82 1.34 5.00
117 INT326191 Localization of Slc12a5 1 0.14 0.85 1.32 5.00
118 INT95116 Negative_regulation of PDGFA 24 0.57 19.56 1.29 5.00
119 INT14946 Binding of SPARCL1 5 0.31 6.57 1.29 5.00
120 INT210392 Regulation of PDGFA 10 0.36 11.41 1.12 5.00
121 INT335383 Positive_regulation of Srd5a2 1 0.37 1.04 1.12 5.00
122 INT335388 Positive_regulation of Slc30a3 1 0.49 1.04 1.11 5.00
123 INT112095 Negative_regulation of Nmur2 2 0.43 1.49 1.1 5.00
124 INT280858 Localization of IFNAR1 5 0.39 4.5 1.09 5.00
125 INT335360 Positive_regulation of Gene_expression of Per2 1 0.49 1.03 0.92 5.00
126 INT266561 Negative_regulation of Positive_regulation of Sorbs1 1 0.01 1.01 0.88 5.00
127 INT335369 Gene_expression of Npas2 1 0.54 0.92 0.86 5.00
128 INT335378 Negative_regulation of Gene_expression of Npas2 1 0.40 0.92 0.86 5.00
129 INT266562 Gene_expression of Fbn2 1 0.05 0.93 0.84 5.00
130 INT266563 Positive_regulation of Gene_expression of Fbn2 1 0.04 0.93 0.84 5.00
131 INT266567 Regulation of Localization of Nav1 1 0.21 1.89 0.83 5.00
132 INT335364 Negative_regulation of Transcription of Hspg2 1 0.07 0.91 0.8 5.00
133 INT335373 Transcription of Hspg2 1 0.08 0.86 0.77 5.00
134 INT277239 Regulation of Bcl6 2 0.35 0.54 0.76 5.00
135 INT147008 Negative_regulation of Gene_expression of S100b 2 0.27 0.55 0.74 5.00
136 INT335368 Positive_regulation of Il22ra2 1 0.53 0.94 0.73 5.00
137 INT335359 Positive_regulation of Gene_expression of Psip1 1 0.59 0.85 0.7 5.00
138 INT335367 Gene_expression of Psip1 1 0.66 0.85 0.7 5.00
139 INT89520 Regulation of COL1A1 8 0.32 3.21 0.66 5.00
140 INT169589 Gene_expression of Cd7 2 0.44 1.49 0.65 5.00
141 INT216770 Gene_expression of Cadps 3 0.34 0.86 0.6 5.00
142 INT335379 Gene_expression of Lgals2 1 0.56 0.78 0.6 5.00
143 INT335375 Negative_regulation of Btk 1 0.22 0.56 0.59 5.00
144 INT335380 Negative_regulation of Bcl6 1 0.27 0.56 0.59 5.00
145 INT335374 Regulation of Btk 1 0.23 0.54 0.58 5.00
146 INT335370 Gene_expression of Il22 1 0.45 0.71 0.56 5.00
147 INT335376 Negative_regulation of Zhx2 1 0.33 0.81 0.51 5.00
148 INT335384 Positive_regulation of Gene_expression of Zhx2 1 0.53 0.79 0.45 5.00
149 INT335382 Gene_expression of Zhx2 1 0.59 0.79 0.45 5.00
150 INT175759 Gene_expression of ARNTL 9 0.75 0.8 0.44 5.00
151 INT266569 Negative_regulation of Gene_expression of Cadps 1 0.13 0.51 0.37 5.00
152 INT335365 Positive_regulation of Lgals2 1 0.42 0.58 0.36 5.00
153 INT266564 Negative_regulation of Protein_catabolism of Nav1 1 0.29 0.42 0.34 5.00
154 INT259761 Negative_regulation of Fbn2 2 0.03 1.1 0.34 5.00
155 INT266568 Protein_catabolism of Nav1 1 0.44 0.41 0.33 5.00
156 INT308015 Phosphorylation of IFNAR1 1 0.27 1.11 0.28 5.00
157 INT266560 Positive_regulation of Positive_regulation of Fbn2 1 0.05 0.5 0.26 5.00
158 INT266566 Regulation of Transcription of Fig4 2 0.11 0.56 0.23 5.00
159 INT335357 Binding of Lrrc10 1 0.47 0.34 0.21 5.00
160 INT335371 Binding of Lrrfip1 1 0.35 0.34 0.21 5.00
161 INT335377 Localization of Psip1 1 0.63 0.3 0.2 5.00
162 INT335386 Localization of Bcl6 1 0.39 0.23 0.16 5.00
163 INT335362 Localization of Btk 1 0.36 0.23 0.16 5.00
164 INT335372 Regulation of Localization of Cnr2 1 0.18 0.23 0.16 5.00
165 INT335381 Localization of Srd5a2 1 0.55 0.24 0.15 5.00
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