P:Clonidine

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pChart

Pain Term
Category Drug
Synonyms None
Pain Specific Yes
Documents 11738
Hot Single Events 200
Hot Interactions 200

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Clonidine. They are ordered first by their pain relevance and then by number of times they were reported for Clonidine. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT16531 Ghrh Positive_regulation of Localization of Gh1 31 0.64 2.12 14.2 100.00
2 INT11248 Gh Positive_regulation of Ghrh 2 0.26 0.09 4.04 100.00
3 INT26892 OGG1 Negative_regulation of Gene_expression of Gh1 1 0.12 0 2.53 100.00
4 INT30134 Binding of TPP1 and S100A9 1 0.13 0.74 1.69 100.00
5 INT9180 Ghrh Regulation of Localization of Gh 3 0.24 0.25 2.18 100.00
6 INT185143 Elane Positive_regulation of Pik3r1 1 0.01 0 1.72 100.00
7 INT18786 Binding of Adra2a and Nisch 2 0.19 0 1.7 100.00
8 INT26893 OGG1 Negative_regulation of Gh1 1 0.12 0 1.37 100.00
9 INT25272 Binding of Ggh and Ghrh 1 0.22 0 0.97 100.00
10 INT19758 Ghrh Positive_regulation of Positive_regulation of Gh 1 0.26 0 0.98 100.00
11 INT1315 Pomc Positive_regulation of Localization of Gnrhr 3 0.38 0.16 2.16 100.00
12 INT48341 Negative_regulation of Pde8a Regulation of Ahsg 1 0.22 0 0.9 100.00
13 INT15730 Ghrh Positive_regulation of Gnrhr 2 0.14 0.08 0.84 100.00
14 INT48342 Pde8a Regulation of Ahsg 1 0.24 0 0.9 100.00
15 INT3575 Sst Regulation of Localization of Gnrhr 2 0.24 0 1.24 100.00
16 INT20688 Adra2a Regulation of Localization of Gh1 1 0.26 0.37 0.7 100.00
17 INT14197 Pde2a Positive_regulation of Localization of Gh1 2 0.04 0 1.08 100.00
18 INT30409 Negative_regulation of Negative_regulation of Positive_regulation of Gh1 1 0.02 0.1 0.7 100.00
19 INT30408 Negative_regulation of Negative_regulation of Gh1 1 0.02 0.1 0.7 100.00
20 INT29837 Gnrh1 Positive_regulation of LH 6 0.67 0 3.53 100.00
21 INT62250 Fdft1 Regulation of Adrb1 1 0.00 0 0.65 100.00
22 INT62249 Ghrh Regulation of Adrb1 1 0.00 0 0.62 100.00
23 INT153921 Positive_regulation of Adra2a Regulation of Ednrb 1 0.01 0 0.66 100.00
24 INT16302 GHRH Regulation of Localization of GH1 1 0.65 0.62 0.4 100.00
25 INT101001 GHRH Regulation of Localization of INS 1 0.28 0 0.47 100.00
26 INT101003 GHRH Regulation of Localization of GGH 1 0.29 0 0.47 100.00
27 INT34865 Ghrh Positive_regulation of Gene_expression of Gnrhr 1 0.07 0 0.37 100.00
28 INT33995 Ghrh Regulation of Gnrhr 2 0.18 0.43 0.77 100.00
29 INT185140 Elane Positive_regulation of Prkca 1 0.00 0 0.74 100.00
30 INT26648 Binding of CEL and HP 1 0.04 0 0.58 100.00
31 INT68482 Cga Regulation of Gh 1 0.00 1.89 0.31 100.00
32 INT31713 Adra2c Regulation of Localization of Ins1 1 0.22 0.31 0.35 100.00
33 INT122237 Gnrh1 Positive_regulation of Gh1 1 0.20 0 0.43 100.00
34 INT51088 Binding of CDS1 and PRMT1 1 0.06 0 0.28 100.00
35 INT42354 Dbh Regulation of Localization of Gh1 1 0.07 0 0.28 100.00
36 INT27788 Gnrh1 Positive_regulation of Positive_regulation of LH 3 0.55 0.17 1.72 100.00
37 INT17528 Prl Regulation of Gh 2 0.28 1.28 0.73 100.00
38 INT36511 Binding of Htr2a and Eef1a1 1 0.22 0 0.62 100.00
39 INT36512 Binding of Htr2a and Man2a2 1 0.19 0 0.62 100.00
40 INT16896 GHSR Regulation of GH1 2 0.23 0.24 0.36 100.00
41 INT103386 Negative_regulation of SLC9A1 Negative_regulation of Gene_expression of IL8 1 0.02 0.97 0.36 100.00
42 INT25375 Trh Regulation of Gh 1 0.04 1.01 0.28 100.00
43 INT122236 Gnrh1 Positive_regulation of Trh 1 0.29 0 0.19 100.00
44 INT75355 Negative_regulation of GCG Regulation of Gh 1 0.01 1.26 0.18 100.00
45 INT75356 GCG Regulation of Gh 1 0.01 1.25 0.18 100.00
46 INT36568 AGT Positive_regulation of FBF1 1 0.39 0.5 0.17 100.00
47 INT36567 Negative_regulation of AGT Positive_regulation of FBF1 1 0.36 0.5 0.17 100.00
48 INT83827 Negative_regulation of Binding of Adrb1 and Pnmt 1 0.02 0 0.1 100.00
49 INT83831 Binding of PNMT and Adrb1 1 0.02 0 0.1 100.00
50 INT83828 Binding of Adrb1 and Pnmt 1 0.01 0 0.1 100.00
51 INT34307 Mastl Regulation of Localization of Gnrh1 1 0.14 0 0.1 100.00
52 INT83832 Negative_regulation of Binding of PNMT and Adrb1 1 0.02 0 0.1 100.00
53 INT27844 Binding of INS and Gh 1 0.03 0.1 0.1 100.00
54 INT25501 Gnrhr Positive_regulation of Igf1 1 0.12 0.09 0.1 100.00
55 INT34308 Mastl Positive_regulation of Localization of Gnrh1 1 0.24 0 0.1 100.00
56 INT27841 Binding of INS and GAL 1 0.04 0.1 0.1 100.00
57 INT142206 Negative_regulation of Adcyap1 Positive_regulation of Gh 1 0.04 0 0.54 99.98
58 INT93953 Negative_regulation of CGA Positive_regulation of ADCY1 1 0.03 0 0.27 99.98
59 INT122232 Trh Positive_regulation of Positive_regulation of LH 1 0.18 0 0.24 99.92
60 INT122225 Trh Positive_regulation of Gh1 1 0.06 0 0.24 99.92
61 INT122222 Trh Positive_regulation of LH 1 0.18 0 0.24 99.92
62 INT75283 SST Negative_regulation of Localization of INS 2 0.47 1.45 0.96 99.92
63 INT34834 Ghrh Positive_regulation of Gene_expression of Gh1 2 0.65 0 1.4 99.88
64 INT78444 Binding of GH1 and IGF1 4 0.16 2.82 0.37 99.88
65 INT10844 Ghrh Regulation of Gh 13 0.13 4.77 4.71 99.84
66 INT40470 GH1 Positive_regulation of GHRH 1 0.06 0 0.67 99.84
67 INT40471 GH1 Positive_regulation of POMC 1 0.25 0 0.67 99.84
68 INT67553 Ghrh Positive_regulation of Regulation of Gh 1 0.04 0.55 0.39 99.84
69 INT26468 Ghrh Positive_regulation of Localization of Gh 21 0.37 3.26 9.21 99.82
70 INT16221 Ghrh Positive_regulation of Gh 8 0.21 1.89 4.08 99.80
71 INT43966 Ins1 Negative_regulation of Gh1 1 0.09 0.33 0.1 99.80
72 INT93952 CGA Positive_regulation of ADCY1 1 0.03 0 0.27 99.78
73 INT68479 Gnrh1 Regulation of Lhb 1 0.00 1.58 0.25 99.72
74 INT13729 GHRH Positive_regulation of Localization of GH1 13 0.62 0.59 3.2 99.70
75 INT43647 Binding of Eef1a1 and Man2a2 1 0.16 0.23 0.7 99.68
76 INT83220 Gucy1a2 Positive_regulation of Positive_regulation of Glp1r 1 0.02 0 0.26 99.68
77 INT81295 Ifng Positive_regulation of Gene_expression of Nos2 4 0.39 0.87 2.05 99.64
78 INT84603 Adrb1 Regulation of Gene_expression of Aqp2 1 0.00 0 0.56 99.64
79 INT66188 Binding of ADRB2 and CDSN 1 0.01 0 0.51 99.62
80 INT17394 Adra2a Positive_regulation of GNAI1 1 0.02 0.37 0.1 99.62
81 INT2687 Negative_regulation of Binding of Thra and SGSM3 1 0.43 0.1 0.62 99.58
82 INT31415 Regulation of Cocia8 Positive_regulation of Ins1 1 0.00 0 0.7 99.56
83 INT142207 Adcyap1 Positive_regulation of Localization of Gh 1 0.07 0 1.3 99.52
84 INT142208 Adcyap1 Positive_regulation of Transcription of Gh 1 0.05 0 0.77 99.52
85 INT142210 Adcyap1 Positive_regulation of Gh 1 0.05 0 0.77 99.52
86 INT142209 Adcyap1 Positive_regulation of Gene_expression of Gh 1 0.05 0 0.63 99.52
87 INT71518 Binding of INSRR and Nisch 1 0.00 0.22 0.35 99.52
88 INT26190 PTAFR Regulation of AVP 1 0.16 0 0.14 99.52
89 INT125748 Binding of LEP and Gh 1 0.00 0.52 0.24 99.48
90 INT35157 GH1 Regulation of GHRH 3 0.17 0.5 0.99 99.48
91 INT90381 Binding of GH1 and LAMC2 1 0.34 0.05 0.81 99.44
92 INT90382 Binding of CRH and GH1 1 0.34 0.05 0.81 99.44
93 INT18197 Ghrh Positive_regulation of Localization of Ggh 4 0.46 0 2.23 99.40
94 INT30135 S100A9 Positive_regulation of REN 1 0.32 0.32 1 99.40
95 INT2686 Binding of Thra and SGSM3 1 0.36 0.1 0.61 99.38
96 INT2685 S100A6 Positive_regulation of Regulation of Thra 1 0.47 0.09 0.58 99.28
97 INT2684 S100A6 Regulation of Regulation of Thra 1 0.45 0.09 0.58 99.28
98 INT84602 Binding of Adrb1 and Avp 1 0.00 0 0.36 99.28
99 INT110033 Adrb1 Positive_regulation of Gene_expression of Il12a 1 0.05 0 0.99 99.28
100 INT31417 Cocia8 Positive_regulation of Ins1 1 0.01 0 0.7 99.24
101 INT16894 Regulation of GHRH Regulation of GH1 2 0.37 0 0.72 99.24
102 INT68872 Ghrh Regulation of IGF1 1 0.09 0.18 0.26 99.20
103 INT54260 SST Regulation of GH1 1 0.18 0.06 0.81 99.16
104 INT35159 FSHR Regulation of PRL 2 0.34 0 0.6 99.12
105 INT35154 PLOD1 Regulation of PRL 2 0.17 0 0.6 99.12
106 INT145576 Binding of Adra2c and Hcn4 1 0.21 0.19 0.4 99.08
107 INT145574 Regulation of Binding of Adra2c and Hcn4 1 0.26 0.19 0.4 99.08
108 INT52562 Lhb Positive_regulation of Prl 3 0.00 1.09 1.02 99.04
109 INT73165 Gh Positive_regulation of Prl 2 0.00 0.95 0.2 99.04
110 INT16891 GHRH Regulation of GH1 5 0.37 1.94 1.82 98.92
111 INT47101 Adra1a Regulation of Localization of Gnrhr 1 0.02 0.24 0.44 98.88
112 INT32193 Olr824 Positive_regulation of Localization of LH 1 0.08 0 0.53 98.80
113 INT28387 Pomc Positive_regulation of Localization of LH 2 0.40 0.28 2.07 98.80
114 INT1314 Pomc Regulation of Localization of Gnrhr 2 0.16 0.14 1.45 98.76
115 INT145575 Binding of Adra2c and Hcn2 1 0.21 0.19 0.4 98.72
116 INT145577 Regulation of Binding of Adra2c and Hcn2 1 0.25 0.19 0.4 98.72
117 INT25026 PLOD1 Regulation of FSHR 4 0.19 0.38 1.15 98.56
118 INT33575 ADRB1 Positive_regulation of Localization of Ahsp 1 0.00 0.33 0.73 98.56
119 INT68066 Binding of MAOA and NRL 1 0.34 0 0.39 98.56
120 INT25526 Dst Regulation of Gh 1 0.00 0.26 0.34 98.44
121 INT78446 Binding of GH1 and IGFBP3 1 0.11 0.48 0.1 98.24
122 INT31108 Ghrh Negative_regulation of Gh1 2 0.55 0 0.95 98.20
123 INT52435 Positive_regulation of Binding of Sst and Fdft1 1 0.09 0.08 0.98 98.20
124 INT26948 Pomc Positive_regulation of Localization of Gh1 2 0.22 0.15 1.99 98.16
125 INT12711 POMC Regulation of Prl 1 0.04 1.25 0.7 98.12
126 INT12710 Gnrhr Regulation of Prl 1 0.00 0.63 0.35 98.12
127 INT1390 Trh Positive_regulation of Prl 14 0.67 4.42 4.39 98.04
128 INT18593 Binding of Sst and Fdft1 2 0.11 0.08 2.12 98.02
129 INT81968 Binding of PLEK and Adra2a 1 0.07 0.1 0.7 98.00
130 INT73168 Lhb Positive_regulation of Gh 2 0.00 0.95 0.2 98.00
131 INT73167 Regulation of Lhb Positive_regulation of Gh 1 0.00 0.48 0.1 98.00
132 INT86960 ADRA1D Negative_regulation of Prl 1 0.00 0 0.97 97.92
133 INT31182 Adra2a Regulation of Localization of Gh 1 0.01 0.35 0.32 97.84
134 INT32482 Ghrh Positive_regulation of Prl 3 0.18 0.26 1.62 97.84
135 INT30125 Binding of Gh and Ghrh 2 0.06 0.36 0.7 97.76
136 INT39143 ras Positive_regulation of Gene_expression of REN 1 0.01 1.35 0.45 97.64
137 INT29053 Regulation of Binding of INS and INSRR 1 0.01 0.24 0.4 97.64
138 INT29252 Regulation of INS Positive_regulation of GH1 1 0.26 0.08 0.54 97.60
139 INT25156 TRH Regulation of PRL 2 0.27 0.81 0.56 97.56
140 INT59548 Negative_regulation of Avp Positive_regulation of Crh 1 0.04 0.08 0.47 97.44
141 INT26448 Adra2a Regulation of Positive_regulation of Npy 1 0.06 0 0.46 97.36
142 INT59547 Avp Positive_regulation of Crh 2 0.14 1.13 1.47 97.26
143 INT59546 Avp Positive_regulation of Localization of Crh 1 0.05 0.08 0.47 97.26
144 INT39142 ras Positive_regulation of REN 1 0.01 1.34 0.45 97.24
145 INT94665 Nisch Negative_regulation of Maoa 1 0.07 0 0.83 97.24
146 INT81832 Binding of ADRA2C and CRYGS 1 0.06 0 0.66 97.24
147 INT71519 Edn1 Positive_regulation of Gene_expression of Adarb1 1 0.02 0.48 0.31 96.88
148 INT63543 Binding of Adra2a and Serpini1 1 0.13 0 1 96.82
149 INT72202 GH1 Regulation of SST 1 0.28 0 0.24 96.76
150 INT36875 Binding of EDNRA and SYNCRIP 1 0.01 0 0.24 96.68
151 INT84605 Binding of Avp and Avp Regulation of Aqp2 1 0.07 0 0.7 96.64
152 INT42865 Binding of Adrb2 and Man2a2 1 0.23 1.03 0.85 96.64
153 INT42864 Regulation of Binding of Adrb2 and Man2a2 1 0.28 1.03 0.85 96.64
154 INT84604 Aqp2 Regulation of Binding of Avp and Avp 1 0.12 0 0.35 96.64
155 INT84600 Binding of Avp and Aqp2 1 0.17 0 0.35 96.64
156 INT145718 Positive_regulation of Plat Positive_regulation of Bdnf 1 0.20 0 0.56 96.52
157 INT18520 Adra2c Positive_regulation of Localization of Ins1 3 0.41 0.63 1.66 96.40
158 INT29052 Binding of INS and INSRR 1 0.02 0.23 0.4 96.32
159 INT29255 INS Positive_regulation of INS Positive_regulation of GH1 1 0.47 0.08 0.53 96.24
160 INT29253 INS Positive_regulation of GH1 1 0.44 0.08 0.53 96.24
161 INT56459 ADRA2C Positive_regulation of Localization of AHSP 1 0.23 0 0.78 96.20
162 INT72203 GH1 Regulation of OGG1 1 0.10 0 0.46 96.12
163 INT115875 Col5a1 Positive_regulation of Localization of Gcg 1 0.08 0 0.23 96.12
164 INT62107 Ghrh Negative_regulation of Regulation of Gh 1 0.06 0 0.39 96.00
165 INT59396 Tead1 Negative_regulation of Negative_regulation of Man2a2 1 0.00 0 0.86 95.92
166 INT35252 Gene_expression of Ghrh Positive_regulation of Localization of Gh1 1 0.49 0 0.93 95.88
167 INT62111 SLC25A4 Negative_regulation of Regulation of Ghrh 1 0.41 0 0.9 95.80
168 INT62110 SLC25A4 Negative_regulation of Regulation of Gh 1 0.06 0 0.39 95.80
169 INT37157 Pir Positive_regulation of Kncn 1 0.01 0.38 0.3 95.60
170 INT149652 Zfp36 Regulation of Nos2 1 0.09 0.42 0.47 95.52
171 INT121742 Prkcg Positive_regulation of Ephb1 3 0.49 0.99 2.6 95.48
172 INT59395 Tead1 Negative_regulation of Man2a2 1 0.00 0 0.86 95.36
173 INT45258 SLAMF6 Positive_regulation of Drd2 1 0.00 0 0.55 95.32
174 INT108611 Adra2a Regulation of Gene_expression of Nos1 1 0.10 0 0.75 95.28
175 INT149947 Ephb1 Positive_regulation of Prkcg 1 0.27 0.07 0.26 95.16
176 INT15731 SST Regulation of Gh 1 0.04 0 0.62 95.12
177 INT17187 Binding of Adra2a and Fabp6 1 0.16 0.69 0.61 94.96
178 INT17186 Positive_regulation of Binding of Adra2a and Fabp6 1 0.21 0.69 0.61 94.96
179 INT34987 Adra2a Positive_regulation of Localization of Gnrhr 1 0.43 0 0.4 94.96
180 INT121830 Binding of Scgb1d2 and Lnp 1 0.02 0.33 0.26 94.88
181 INT70656 Adra2a Regulation of Gene_expression of Npy 1 0.23 0 0.38 94.72
182 INT90593 Binding of Eif3h and Man2a2 1 0.01 0.32 0.38 94.60
183 INT70930 Sstr2 Regulation of Localization of Gh1 1 0.15 0 0.49 94.52
184 INT52333 Fos Regulation of Gene_expression of Synm 1 0.02 0 0.33 94.48
185 INT80833 Oxt Regulation of Ins1 1 0.04 0 0.53 94.44
186 INT80835 Oxt Positive_regulation of Regulation of Ins1 1 0.04 0 0.53 94.44
187 INT80836 Oxt Regulation of Sst 1 0.07 0 0.53 94.44
188 INT80834 Oxt Regulation of Cck 1 0.13 0 0.53 94.44
189 INT80832 Oxt Regulation of Gast 1 0.10 0 0.53 94.44
190 INT60907 Gh1 Negative_regulation of TPP1 Positive_regulation of Gh1 1 0.00 0 0.22 94.44
191 INT30411 Ghrh Regulation of Gene_expression of Gh1 1 0.40 0.12 0.9 94.20
192 INT30412 Sst Regulation of Gene_expression of Gh1 1 0.19 0.06 0.45 94.20
193 INT7849 Man2a2 Positive_regulation of Localization of Gcg 1 0.08 0 0.51 94.08
194 INT19887 GHRH Positive_regulation of Positive_regulation of GH1 2 0.56 0.3 1.08 94.00
195 INT4220 Npepo Negative_regulation of Prl 1 0.30 0 0.37 94.00
196 INT13014 Avp Positive_regulation of Adcy5 1 0.00 0.07 0.13 93.84
197 INT44654 Phc1 Negative_regulation of Adra1a 1 0.00 0.4 0.33 93.80
198 INT60909 TPP1 Positive_regulation of Gh1 1 0.00 0 0.22 93.72
199 INT149948 Ephb1 Negative_regulation of Phosphorylation of Map2 1 0.37 0.07 0.25 93.72
200 INT66801 Oxt Regulation of Localization of Avp 1 0.08 0 0.48 93.68

Single Events

The table below shows the top 200 pain related interactions that have been reported for Clonidine. They are ordered first by their pain relevance and then by number of times they were reported in Clonidine. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT1893 Localization of Gh 1041 0.79 340.23 256.58 100.00
2 INT3448 Positive_regulation of Gh 521 0.69 180.03 161.18 100.00
3 INT252 Localization of GH1 529 0.80 227.4 122.05 100.00
4 INT767 Localization of Gnrhr 565 0.80 106.68 214.57 100.00
5 INT880 Positive_regulation of Localization of Gh1 304 0.70 14.79 150.23 100.00
6 INT1530 Regulation of Gh 382 0.61 115.96 112.47 100.00
7 INT5865 Positive_regulation of Localization of Gh 282 0.69 84.86 93.5 100.00
8 INT1498 Gene_expression of Gh 521 0.75 220.84 81.16 100.00
9 INT914 Positive_regulation of GH1 292 0.69 100.7 84.91 100.00
10 INT1497 Negative_regulation of Gh 415 0.59 192.95 74.71 100.00
11 INT874 Positive_regulation of Gh1 244 0.70 27.17 97.98 100.00
12 INT5095 Localization of Ghrh 185 0.81 28.09 62.08 100.00
13 INT875 Regulation of Localization of Gh1 166 0.62 12.87 84.97 100.00
14 INT148 Positive_regulation of Gnrhr 182 0.70 47.44 79.64 100.00
15 INT1309 Positive_regulation of Localization of Gnrhr 152 0.69 24.25 81.56 100.00
16 INT881 Negative_regulation of Localization of Gh1 164 0.58 15.1 75.28 100.00
17 INT921 Regulation of GH1 172 0.60 52.88 51.04 100.00
18 INT249 Localization of GHRH 215 0.80 78.02 51.87 100.00
19 INT50 Negative_regulation of Localization of Ren 87 0.59 14.94 30.22 100.00
20 INT1782 Regulation of Gh1 125 0.62 22 55.74 100.00
21 INT770 Regulation of Localization of Gnrhr 127 0.61 17.91 58.23 100.00
22 INT255 Regulation of Localization of GH1 89 0.62 18.71 35.3 100.00
23 INT19 Regulation of Gnrhr 131 0.62 36.4 55.66 100.00
24 INT7059 Regulation of Adra2a 89 0.62 18.24 48.43 100.00
25 INT957 Positive_regulation of GHRH 136 0.70 36.84 40.52 100.00
26 INT1894 Negative_regulation of Localization of Gh 168 0.58 64.12 43.56 100.00
27 INT3161 Regulation of Localization of Gh 163 0.61 35.43 59.45 100.00
28 INT248 Positive_regulation of Localization of GH1 137 0.69 49.25 32.92 100.00
29 INT5623 Positive_regulation of Nppa 174 0.70 69.96 52.33 100.00
30 INT2275 Negative_regulation of Localization of Ins1 183 0.59 51.02 44.94 100.00
31 INT49 Negative_regulation of Ren 129 0.59 37.48 35.62 100.00
32 INT873 Gene_expression of Gh1 130 0.76 26.15 46.75 100.00
33 INT1781 Negative_regulation of Gh1 127 0.59 16.94 51.77 100.00
34 INT7608 Positive_regulation of Adra2a 66 0.70 17.81 35.15 100.00
35 INT9179 Positive_regulation of Localization of Ghrh 42 0.70 7.05 18.1 100.00
36 INT812 Localization of INS 1026 0.81 515.6 145.31 100.00
37 INT985 Negative_regulation of GH1 213 0.57 89.53 32.39 100.00
38 INT1474 Regulation of Localization of Ins1 132 0.61 25.96 43.07 100.00
39 INT5100 Positive_regulation of Ghrh 100 0.64 24.2 30.21 100.00
40 INT10841 Positive_regulation of Gene_expression of Gh 101 0.59 45.39 16.96 100.00
41 INT16303 Negative_regulation of Localization of GH1 89 0.59 37.31 22.15 100.00
42 INT531 Gene_expression of GH1 376 0.75 193.45 46.24 100.00
43 INT162 Regulation of Prl 794 0.62 165.01 322.24 100.00
44 INT157 Positive_regulation of Localization of Prl 790 0.70 104.54 374.78 100.00
45 INT738 Regulation of POMC 459 0.62 111.19 243.74 100.00
46 INT397 Localization of SST 232 0.81 58.05 101.19 100.00
47 INT250 Regulation of GHRH 65 0.61 17.46 23.19 100.00
48 INT6385 Regulation of Man2a2 48 0.61 7.8 24.68 100.00
49 INT7779 Negative_regulation of Adra2a 47 0.58 9.45 28 100.00
50 INT253 Regulation of PRL 184 0.62 47.27 65.79 100.00
51 INT4242 Negative_regulation of Positive_regulation of Gh1 26 0.58 1.47 15.75 100.00
52 INT18323 Negative_regulation of Localization of Ins1 122 0.58 45.74 23.04 100.00
53 INT13454 Positive_regulation of Positive_regulation of Gh 49 0.68 14.53 18.49 100.00
54 INT653 Negative_regulation of Localization of REN 67 0.59 20.33 16.7 100.00
55 INT7364 Regulation of Ghrh 49 0.58 8.05 19.05 100.00
56 INT8248 Binding of Adra2a 43 0.48 6.72 22.17 100.00
57 INT4298 Positive_regulation of Positive_regulation of Gh1 30 0.50 1.79 13.32 100.00
58 INT1361 Negative_regulation of Gnrhr 118 0.58 57.77 35.54 100.00
59 INT6196 Regulation of Nppa 83 0.62 30.31 30.18 100.00
60 INT739 Negative_regulation of POMC 358 0.59 102.28 166.77 100.00
61 INT161 Regulation of Localization of Prl 615 0.62 65.37 298.66 100.00
62 INT480 Negative_regulation of Localization of Avp 151 0.59 27.64 63.72 100.00
63 INT326 Gene_expression of Gnrhr 105 0.76 35.87 34.93 100.00
64 INT2660 Negative_regulation of Fabp6 58 0.49 33.74 18.27 100.00
65 INT1116 Regulation of Ren 103 0.62 27.66 33.26 100.00
66 INT7474 Gene_expression of Man2a2 38 0.67 3.31 18.42 100.00
67 INT693 Negative_regulation of Localization of SST 46 0.59 8.57 21.75 100.00
68 INT1322 Positive_regulation of Localization of INS 293 0.70 120.86 45.98 100.00
69 INT14114 Binding of Adra2a 30 0.48 4.24 18.53 100.00
70 INT16530 Gene_expression of Ghrh 45 0.77 6.22 13.44 100.00
71 INT3030 Gene_expression of Adra2a 37 0.68 5.58 19.76 100.00
72 INT2140 Regulation of REN 104 0.62 28.24 24.49 100.00
73 INT254 Regulation of Localization of GHRH 30 0.60 5.17 11.46 100.00
74 INT4207 Regulation of Avp 267 0.62 63.72 115.33 100.00
75 INT5618 Regulation of Localization of Nppa 36 0.62 13.42 17.46 100.00
76 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36 100.00
77 INT955 Gene_expression of GHRH 126 0.78 59.91 20.74 100.00
78 INT251 Regulation of INS 398 0.62 232.47 55.04 100.00
79 INT952 Negative_regulation of GHRH 57 0.56 25.3 10.34 100.00
80 INT19010 Negative_regulation of Localization of Ghrh 27 0.57 4.85 10.5 100.00
81 INT5453 Regulation of Localization of POMC 114 0.62 20.56 56.34 100.00
82 INT2276 Regulation of Ins1 234 0.61 103.78 54.05 100.00
83 INT217 Negative_regulation of Th 134 0.59 26.83 62.63 100.00
84 INT916 Regulation of Localization of PRL 92 0.62 22.98 38.13 100.00
85 INT2085 Positive_regulation of LH 441 0.70 60.15 191.02 100.00
86 INT106525 Phosphorylation of Akt1 436 0.82 183.81 47.82 100.00
87 INT3954 Regulation of Fabp6 33 0.52 15.64 9.27 100.00
88 INT10285 Binding of ADRA1D 102 0.47 25.82 31.11 100.00
89 INT20673 Binding of CDS1 18 0.31 1.96 5.72 100.00
90 INT7327 Regulation of Th 164 0.62 29.67 110.14 100.00
91 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 100.00
92 INT26707 Binding of PPAP2A 21 0.35 6.01 7.43 100.00
93 INT6576 Localization of Adra2a 11 0.71 1.49 7.18 100.00
94 INT327 Negative_regulation of Positive_regulation of Gnrhr 17 0.53 4.22 10.21 100.00
95 INT12455 Negative_regulation of Adra2a 30 0.54 5.63 10.14 100.00
96 INT481 Regulation of Localization of Ren 37 0.62 5.95 11.61 100.00
97 INT12292 Negative_regulation of Positive_regulation of GH1 22 0.58 5.02 8.28 100.00
98 INT65600 Positive_regulation of Casp3 376 0.70 198.44 128.03 100.00
99 INT11510 Negative_regulation of Positive_regulation of Gh 28 0.52 12.71 9.16 100.00
100 INT685 Regulation of AVP 124 0.62 34.9 39.91 100.00
101 INT32903 Negative_regulation of PPAP2A 14 0.48 5.02 7.2 100.00
102 INT5591 Regulation of Gene_expression of Fos 425 0.62 129.06 265.78 100.00
103 INT8742 Regulation of Localization of Ins1 65 0.61 14.98 16.43 100.00
104 INT7697 Positive_regulation of Adra1a 22 0.68 2.3 9.16 100.00
105 INT16356 Regulation of NPPA 33 0.62 13.24 9.53 100.00
106 INT1644 Regulation of FSHR 77 0.55 15.62 21.49 100.00
107 INT5674 Gene_expression of Adra2a 34 0.77 6.14 15.13 100.00
108 INT7395 Localization of GNRH1 399 0.81 62.88 117.68 100.00
109 INT390 Positive_regulation of Agt 170 0.70 61.47 36.08 100.00
110 INT7361 Binding of Ghrh 13 0.45 1.37 5.44 100.00
111 INT1579 Gene_expression of PRL 279 0.78 119.2 55.41 100.00
112 INT13735 Negative_regulation of Regulation of GH1 14 0.42 4.35 5.39 100.00
113 INT16304 Negative_regulation of Positive_regulation of GHRH 9 0.51 2.56 4.25 100.00
114 INT18322 Negative_regulation of Ins1 132 0.58 88.49 22.59 100.00
115 INT21138 Binding of ADRA2A 16 0.48 5.57 6.8 100.00
116 INT1004 Regulation of Sst 140 0.62 18.52 94.84 100.00
117 INT416 Regulation of LH 253 0.62 31.48 125.55 100.00
118 INT1224 Gene_expression of Fabp6 34 0.64 23.69 9.08 100.00
119 INT18785 Binding of Nisch 12 0.43 1.03 4.28 100.00
120 INT30247 Regulation of Adrb1 18 0.44 4.45 8.93 100.00
121 INT3441 Regulation of Localization of Abat 117 0.38 8.67 87.59 100.00
122 INT31810 Binding of HTR2B 6 0.47 2.75 4.36 100.00
123 INT9178 Regulation of Localization of Ghrh 13 0.45 2.28 5.08 100.00
124 INT21632 Positive_regulation of Adh1 32 0.70 15.67 11.65 100.00
125 INT21367 Positive_regulation of AHA 7 0.27 2.77 3.24 100.00
126 INT14029 Regulation of Fdft1 9 0.19 0.68 7.4 100.00
127 INT2587 Regulation of Localization of Gcg 22 0.60 1.73 7.59 100.00
128 INT110 Regulation of Adrb3 33 0.60 8.09 13.84 100.00
129 INT7886 Regulation of Localization of Avp 146 0.62 14.53 72.99 100.00
130 INT7414 Regulation of Localization of SST 31 0.60 4.85 17.46 100.00
131 INT19008 Positive_regulation of Positive_regulation of Ghrh 15 0.49 2.4 4.55 100.00
132 INT695 Binding of POMC 304 0.48 56.66 126.85 100.00
133 INT1499 Negative_regulation of Gene_expression of Gh 58 0.42 25.17 7.86 100.00
134 INT16659 Gene_expression of Eef1a1 34 0.64 6.1 11.85 100.00
135 INT7017 Regulation of Npr1 45 0.52 3.38 20.05 100.00
136 INT92133 Negative_regulation of Ednrb 8 0.42 1.7 4.44 100.00
137 INT33399 Negative_regulation of CDS1 12 0.37 1.97 4.22 100.00
138 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 100.00
139 INT30138 Binding of TPP1 1 0.16 0.74 1.69 100.00
140 INT30136 Binding of S100A9 11 0.48 4.31 2.55 100.00
141 INT14043 Binding of HP 52 0.30 26.56 7.76 100.00
142 INT1648 Regulation of LHB 21 0.61 3.32 9.6 100.00
143 INT3299 Positive_regulation of AGT 126 0.68 79.45 21.91 100.00
144 INT30137 Negative_regulation of TPP1 5 0.37 0.96 2.2 100.00
145 INT2649 Regulation of Calca 433 0.62 146.05 330.95 100.00
146 INT31227 Regulation of Localization of GCG 28 0.48 4.86 5.72 100.00
147 INT122570 Negative_regulation of Akt1 173 0.59 91.44 25.53 100.00
148 INT2123 Positive_regulation of Gnrh1 209 0.70 24.2 68.97 100.00
149 INT847 Regulation of Lhb 131 0.61 22.08 46.54 100.00
150 INT2960 Regulation of Dbh 32 0.47 10.32 18.94 100.00
151 INT919 Regulation of Positive_regulation of GH1 7 0.47 1.09 2.75 100.00
152 INT4378 Regulation of Gene_expression of GH1 26 0.47 10.2 4.61 100.00
153 INT26492 Negative_regulation of Localization of GCG 73 0.58 22.2 9.48 100.00
154 INT11628 Regulation of Localization of Pomc 44 0.61 10.46 18.66 100.00
155 INT19104 Regulation of Gene_expression of Gh 24 0.40 8.42 3.88 100.00
156 INT1360 Negative_regulation of Regulation of Gnrhr 5 0.43 0.77 2.86 100.00
157 INT3962 Regulation of AGT 50 0.62 20.96 13.01 100.00
158 INT19900 Binding of GHRH 22 0.37 5.75 5 100.00
159 INT47 Negative_regulation of Negative_regulation of Ren 2 0.59 0.34 1.25 100.00
160 INT1158 Regulation of Agt 106 0.61 29.4 30.29 100.00
161 INT335 Binding of Adra1a 16 0.36 6.16 6 100.00
162 INT8413 Gene_expression of Ptgs1 248 0.78 110.17 108.58 100.00
163 INT11604 Regulation of Positive_regulation of Ghrh 4 0.42 0.62 2.05 100.00
164 INT34413 Negative_regulation of Pia1 4 0.12 0.24 2.17 100.00
165 INT122569 Negative_regulation of Gene_expression of Akt1 34 0.54 17.15 4.44 100.00
166 INT114881 Gene_expression of Akt1 227 0.78 102.49 31.81 100.00
167 INT1650 Regulation of TSHR 3 0.28 0.88 1.99 100.00
168 INT25198 Regulation of Pkia 3 0.27 0.51 3.31 100.00
169 INT5128 Positive_regulation of Lhb 232 0.69 44.23 71.26 100.00
170 INT9476 Regulation of Gene_expression of Jun 14 0.43 4.25 7.61 100.00
171 INT6459 Regulation of Negative_regulation of Npr1 10 0.53 0.16 6.44 100.00
172 INT27596 Negative_regulation of Positive_regulation of Man2a2 4 0.42 0.47 1.78 100.00
173 INT2055 Regulation of Gnrh1 185 0.62 23.65 71.26 100.00
174 INT7413 Positive_regulation of Localization of SST 37 0.69 5.64 13.94 100.00
175 INT871 Negative_regulation of Gene_expression of Prl 53 0.58 18.89 17.79 100.00
176 INT28983 Regulation of Htr2b 3 0.22 0.26 3.96 100.00
177 INT31923 Positive_regulation of Positive_regulation of Adra2a 7 0.44 1.88 2.89 100.00
178 INT3894 Negative_regulation of Localization of Gcg 18 0.52 2.7 5.77 100.00
179 INT51468 Regulation of Adora2a 8 0.48 1.5 4.84 100.00
180 INT20752 Binding of Dspp 2 0.09 0.1 1.26 100.00
181 INT7847 Positive_regulation of Localization of Adra2a 2 0.40 0.22 1.28 100.00
182 INT26123 Regulation of Ep300 6 0.23 1.22 2.03 100.00
183 INT22491 Binding of Atrn 23 0.30 4.51 7.79 100.00
184 INT36400 Regulation of SCN10A 7 0.62 2.73 1.97 100.00
185 INT3948 Regulation of Cck 291 0.62 58.07 255.88 100.00
186 INT1794 Regulation of Localization of CGA 136 0.57 13.39 59.07 100.00
187 INT33490 Regulation of Krt2 1 0.02 0.62 0.84 100.00
188 INT3217 Regulation of Ins1 154 0.62 87.11 27.29 100.00
189 INT14582 Negative_regulation of Negative_regulation of Sst 9 0.56 0.52 8.38 100.00
190 INT52813 Regulation of Localization of CALCA 8 0.62 3.16 5.89 100.00
191 INT60672 Regulation of Gene_expression of CALCA 3 0.61 1.76 2.85 100.00
192 INT20687 Positive_regulation of Regulation of Adra2a 1 0.35 1.07 0.95 100.00
193 INT7620 Localization of TPO 4 0.26 5.35 0.88 100.00
194 INT24761 Positive_regulation of Negative_regulation of SST 2 0.49 0.86 1.01 100.00
195 INT8358 Negative_regulation of Localization of CALCA 25 0.59 11.79 21.51 100.00
196 INT37148 Negative_regulation of Gene_expression of CALCA 7 0.43 1.91 4.98 100.00
197 INT1046 Gene_expression of LH 180 0.77 29.75 66.87 100.00
198 INT57136 Regulation of Alas1 3 0.51 0.6 0.71 100.00
199 INT32354 Negative_regulation of Regulation of Insr 3 0.33 0.13 1.08 100.00
200 INT3215 Regulation of Gene_expression of Ins1 32 0.52 19.83 4.85 100.00
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