P:Crohn's disease

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pChart

Pain Term
Category Disorder
Synonyms None
Pain Specific No
Documents 1650
Hot Single Events 200
Hot Interactions 58

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Crohn's disease. They are ordered first by their pain relevance and then by number of times they were reported for Crohn's disease. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT342518 HSP90B1 Positive_regulation of Gene_expression of TLR4 1 0.04 0.4 0.13 99.92
2 INT342520 HSP90B1 Positive_regulation of Gene_expression of TLR2 1 0.06 0.4 0.13 99.92
3 INT137416 Binding of SDC1 and Tnf 1 0.00 1.19 0.47 99.84
4 INT290377 NOD2 Negative_regulation of Positive_regulation of TLR2 1 0.24 0.95 0.23 99.58
5 INT348175 Binding of NIDDM1 and PTPN22 1 0.01 2.36 0.99 99.56
6 INT282397 Binding of Irgm1 and Atg16l1 1 0.17 1.18 0.39 99.32
7 INT45035 Binding of HLA-B and HLA-DRB4 2 0.16 0.74 0.44 99.26
8 INT126335 Binding of Pax3 and Tac1 6 0.07 6.22 5.27 99.20
9 INT285105 Gene_expression of PMP2 Positive_regulation of IFNA1 1 0.05 0.93 0.31 99.08
10 INT285100 PMP2 Positive_regulation of IFNA1 1 0.05 0.93 0.31 99.08
11 INT285099 Gene_expression of SLC10A7 Positive_regulation of IFNA1 1 0.10 0.93 0.31 99.08
12 INT285101 SLC10A7 Positive_regulation of IFNA1 1 0.05 0.93 0.31 99.08
13 INT45048 Binding of HLA-B and TNFRSF10B 1 0.21 0.44 0.29 99.00
14 INT307016 IGKV1-17 Positive_regulation of Gene_expression of IL6 1 0.00 1.01 0.56 98.80
15 INT108692 NTF3 Regulation of Gene_expression of IKZF1 1 0.69 0.7 0.49 98.52
16 INT177981 Binding of RUNX1 and SLC22A4 1 0.08 1.04 0.5 98.48
17 INT271511 Binding of Phb2 and Glrb 1 0.04 1.7 0.84 98.24
18 INT329956 Binding of IL2 and IL23R 1 0.33 4.58 1.21 98.12
19 INT329963 Binding of IL21 and IL23R 1 0.30 2.28 0.6 98.12
20 INT282398 Binding of Mefv and Nlrp3 1 0.40 6.8 1.72 97.76
21 INT116966 TNF Negative_regulation of Localization of CCL20 1 0.30 1.49 0.28 97.60
22 INT290378 NOD2 Negative_regulation of TLR2 1 0.27 0.83 0.23 97.10
23 INT238004 Positive_regulation of Binding of Cxcr3 and Cxcl11 1 0.30 1.86 0.51 97.00
24 INT237999 Binding of Cxcr3 and Cxcl11 2 0.45 3.49 1.11 97.00
25 INT238005 Binding of Cxcr3 and Cxcl10 2 0.38 3.73 1.42 97.00
26 INT238009 Binding of Cxcr3 and Cxcl9 3 0.40 4.01 1.37 97.00
27 INT282399 Binding of Mefv and Uncv 1 0.07 1.02 0.26 96.64
28 INT177979 Binding of STAT3 and FOXI2 1 0.00 1.83 0.61 95.32
29 INT246024 IL23A Positive_regulation of SOCS2 1 0.01 0.99 0.43 93.80
30 INT246023 IL6 Positive_regulation of SOCS2 1 0.18 0.99 0.43 93.44
31 INT27872 Positive_regulation of Binding of FCGR1B and HSPD1 1 0.01 1.93 0.56 92.28
32 INT177977 RUNX1 Regulation of CSF1R 1 0.14 1 0.27 92.12
33 INT27871 Binding of FCGR1B and HSPD1 1 0.01 1.93 0.56 91.88
34 INT262178 Binding of Nr1i2 and Abcb1b 1 0.07 1.68 0.21 91.20
35 INT333847 Binding of E2f5 and Mir17 1 0.03 0.52 0.05 90.88
36 INT333849 Binding of Mcm4 and Mir17 1 0.03 0.52 0.05 90.88
37 INT333846 Binding of Wee1 and Mir17 1 0.03 0.52 0.05 90.88
38 INT333840 Binding of Cables1 and Mir17 1 0.03 0.52 0.05 90.88
39 INT333851 Binding of Ccna1 and Mir17 1 0.04 0.52 0.05 90.88
40 INT333841 Binding of Rad51 and Mir17 1 0.02 0.52 0.05 90.88
41 INT285103 PMP2 Regulation of TNF 1 0.06 0.56 0.19 90.80
42 INT285102 PMP2 Regulation of IFNA1 1 0.04 0.56 0.19 90.80
43 INT243639 Twist1 Negative_regulation of Gene_expression of Il2 1 0.24 1.28 0.65 90.48
44 INT238641 Binding of TNF and Ifx 1 0.07 0.86 0.84 88.08
45 INT238642 Binding of TNF and Ada 1 0.03 0.86 0.84 88.08
46 INT253988 Binding of Cd74 and Mif 1 0.36 6.57 2.52 85.28
47 INT238000 Cxcl10 Positive_regulation of Cd4 1 0.21 0.91 0.21 85.20
48 INT238002 Cxcl10 Positive_regulation of Positive_regulation of Cd4 1 0.21 0.91 0.21 85.20
49 INT214590 TIMP1 Regulation of ICAM1 1 0.10 0.29 0.19 84.56
50 INT214591 FOXC1 Regulation of ICAM1 1 0.05 0.29 0.19 84.56
51 INT238001 Cxcl10 Positive_regulation of Gene_expression of Cd40 1 0.17 0.91 0.21 83.60
52 INT238006 Cxcl10 Positive_regulation of Gene_expression of Cd28 1 0.24 0.91 0.21 83.60
53 INT177978 Binding of CSF1R and SNRNP70 1 0.02 1.49 0.28 81.32
54 INT217529 Dss1 Negative_regulation of Gene_expression of Tjp1 1 0.07 0.54 0.04 81.20
55 INT147755 Binding of GNRH1 and TNF 1 0.32 2.37 0.79 80.88
56 INT174657 IL8 Positive_regulation of Gene_expression of LTBR 1 0.01 1.53 0.3 80.56
57 INT174659 TNF Positive_regulation of Gene_expression of LTBR 1 0.22 1.54 0.3 80.56
58 INT174658 TNF Positive_regulation of Gene_expression of ITGAM 1 0.16 1.54 0.3 80.16
59 INT154329 Binding of S100A8 and S100A12 1 0.41 0.5 0.19 79.12
60 INT333839 Binding of Ccna1 and Tpt1 1 0.07 0.48 0.04 75.72
61 INT333852 Binding of Ccna1 and Cdk2 1 0.20 0.48 0.04 75.72
62 INT333844 Binding of Ccna1 and E2f2 1 0.00 0.48 0.04 75.72
63 INT333848 Binding of Ccna1 and Rb1 1 0.04 0.48 0.04 75.72
64 INT196614 TNF Positive_regulation of Positive_regulation of NA 1 0.03 0.88 0.24 74.96
65 INT196615 TNF Positive_regulation of Negative_regulation of DNAH8 1 0.02 0.88 0.24 74.96
66 INT196620 TNF Positive_regulation of Positive_regulation of DNAH8 1 0.03 0.88 0.24 74.96
67 INT196609 IFNG Positive_regulation of Positive_regulation of NA 1 0.03 0.87 0.24 74.48
68 INT196622 IFNG Positive_regulation of Positive_regulation of DNAH8 1 0.03 0.87 0.24 74.48
69 INT196646 IFNG Positive_regulation of Negative_regulation of DNAH8 1 0.03 0.87 0.24 74.48
70 INT243631 Binding of Hand1 and Nfatc1 1 0.04 0.76 0.3 74.16
71 INT349914 Binding of Cdh1 and Jup 1 0.11 0.47 0.07 72.88
72 INT349916 Binding of Ctnnd1 and Cdh1 1 0.17 0.47 0.07 72.88
73 INT253997 Binding of Cd200r1 and Mif 1 0.03 1.02 0.46 72.20
74 INT177980 CSF1R Regulation of PXN 1 0.07 0.48 0.11 71.76
75 INT177982 Binding of RUNX1 and SNRNP70 1 0.01 0.89 0.21 71.72
76 INT150393 Binding of CASP1 and MEFV 2 0.16 2.48 0.45 71.36
77 INT226340 Binding of CD4 and IFNA1 3 0.03 3.84 0.85 71.20
78 INT341594 Binding of ESR1 and HLA-B 1 0.01 0.72 0.57 71.16
79 INT243625 Stat4 Positive_regulation of Gene_expression of Twist1 1 0.39 0.75 0.3 70.40
80 INT238007 Binding of Cxcr3 and Saa 1 0.14 0.95 0.11 70.32
81 INT334879 CASP1 Regulation of IL1B 1 0.03 1.63 0.31 70.16
82 INT243630 Il12a Positive_regulation of Gene_expression of Twist1 1 0.18 0.69 0.3 69.92
83 INT293704 Binding of TNF and DDX41 1 0.00 1.01 0.61 69.32
84 INT238003 Aif1 Regulation of IgG 1 0.00 0.21 0.03 67.36
85 INT237204 Binding of LGALS4 and Cd3e 1 0.15 2.61 0.8 67.28
86 INT243626 Twist1 Regulation of Hand1 1 0.15 1.55 0.72 66.84
87 INT196634 IFNG Negative_regulation of DNAH8 1 0.03 1.49 0.47 66.76
88 INT281319 Binding of F7 and tf 1 0.24 1 0.16 66.56
89 INT342512 Hsp90b1 Positive_regulation of Gene_expression of HSP90B1 1 0.24 0.62 0.03 66.04
90 INT348174 Binding of STAT3 and IL23R 1 0.40 1.9 0.76 63.44
91 INT184094 Gene_expression of Socs3 Negative_regulation of Positive_regulation of Il6 1 0.12 1.49 0.48 60.92
92 INT204791 Binding of Spg7 and Nod2 1 0.03 0.5 0.16 60.24
93 INT245985 Binding of MTR and Mtrr 1 0.06 0.8 0.07 59.28
94 INT204789 Binding of Tlr2 and Nod2 1 0.23 0.44 0.16 58.20
95 INT285104 Binding of TNF and SLC10A7 1 0.12 0.58 0.09 56.76
96 INT254001 Binding of Cxcr4 and Mif 1 0.52 14.17 7.18 56.56
97 INT253996 Binding of Cxcr2 and Cxcr4 1 0.18 0.81 0.44 56.56
98 INT279361 Binding of TNF and KLF1 4 0.00 3.72 2.19 54.92
99 INT196647 IFNG Negative_regulation of NA 1 0.04 0.79 0.24 53.92
100 INT281317 Stx2 Regulation of Gene_expression of tf 1 0.11 1.45 0.03 53.84
101 INT281313 Tlr4 Regulation of Gene_expression of tf 1 0.05 1.45 0.03 53.84
102 INT189796 Binding of EHHADH and Cd14 1 0.13 0.9 0.14 52.40
103 INT179502 Binding of Cd14 and Tlr4 29 0.39 13.77 5.73 50.72
104 INT214594 Binding of FOXC1 and IBD9 1 0.00 1.81 0.28 50.40
105 INT308804 Pld1 Positive_regulation of TNF 1 0.05 2.42 0.99 49.48
106 INT217530 Binding of Tjp1 and Tjp2 1 0.10 0.91 0.1 49.40
107 INT217528 Binding of Tjp1 and Vapb 1 0.00 1.6 0.19 48.64
108 INT296079 IL17A Negative_regulation of Positive_regulation of Gtf3a 1 0.00 0.77 0.13 44.48
109 INT296040 IL17A Regulation of TH1L 1 0.07 0.7 0.12 44.48
110 INT172048 Binding of TNF and MICA 1 0.29 1.63 0.62 44.24
111 INT281302 Binding of Itgam and Fgg 1 0.00 0.62 0.15 43.44
112 INT348173 Binding of HLA-B and IL23R 1 0.15 0.92 0.49 42.24
113 INT166134 Binding of Cxcl12 and Cxcr4 3 0.49 5.69 3.17 41.76
114 INT348177 Binding of HLA-B and ERAP1 1 0.14 0.92 0.49 41.68
115 INT281315 Binding of Gp1bb and Itgam 1 0.00 0.62 0.15 39.60
116 INT253999 Binding of Cxcl12 and Mif 1 0.41 2.26 1.22 39.24
117 INT231349 Il10 Negative_regulation of Gene_expression of TNF 2 0.23 1.82 0.67 38.08
118 INT251580 Il13 Negative_regulation of Gene_expression of TNF 1 0.08 0.96 0.27 38.08
119 INT251567 Il4 Negative_regulation of Gene_expression of Il10 1 0.01 0.96 0.27 38.08
120 INT251581 Il4 Negative_regulation of Gene_expression of TNF 1 0.05 0.95 0.26 38.08
121 INT186393 Binding of TNF and Tnfrsf1a 9 0.37 8.55 1.29 34.40
122 INT186385 Binding of TNF and Tnfrsf1b 4 0.30 3.24 0.42 33.68
123 INT326303 Binding of CRP and FKBP4 1 0.15 1.22 0.41 33.60
124 INT296038 TGFB1 Positive_regulation of Gene_expression of IL23R 1 0.02 0.05 0.11 33.52
125 INT127143 Binding of IL6 and TGFB1 2 0.01 0.16 0.08 33.52
126 INT296041 Binding of TGFB1 and IL21 1 0.01 0.05 0.08 33.52
127 INT296032 IL6 Positive_regulation of Gene_expression of IL23R 1 0.02 0.05 0.11 32.52
128 INT296035 IL21 Positive_regulation of Gene_expression of IL23R 1 0.01 0.05 0.08 32.16
129 INT187222 Binding of Vip and Vipr2 2 0.19 1.82 0.56 31.76
130 INT293703 Binding of DDX41 and C21orf91 1 0.00 0.99 0.42 31.40
131 INT296036 IL6 Positive_regulation of IL17A 1 0.04 0.05 0.17 31.04
132 INT296037 TGFB1 Positive_regulation of IL17A 1 0.02 0 0.17 31.04
133 INT270655 Adipoq Positive_regulation of IL8 Positive_regulation of Adipoq 1 0.00 1.19 0.15 29.80
134 INT270663 Adipoq Positive_regulation of Il6 1 0.02 1.05 0.12 29.80
135 INT270669 Adipoq Positive_regulation of IL8 1 0.01 1.06 0.12 29.80
136 INT270665 Adipoq Positive_regulation of Ccl2 1 0.07 1.06 0.12 29.80
137 INT260578 Binding of IGHG3 and SGSM3 1 0.00 1.07 0 29.72
138 INT260577 Binding of ALPP and SGSM3 1 0.00 1.06 0 28.92
139 INT285560 Il23a Positive_regulation of Il17a 1 0.09 1.45 0.39 27.52
140 INT304582 IL12A Positive_regulation of Gene_expression of TH1L 1 0.21 0.83 0.25 25.40
141 INT304580 IL12A Regulation of Gene_expression of TH1L 1 0.19 0.82 0.25 25.40
142 INT279960 TNF Positive_regulation of Vcam1 1 0.56 0.27 0.18 24.00
143 INT222811 Binding of Hand2 and TH1L 4 0.03 8.26 0.69 23.64
144 INT289625 Binding of RS1 and PSORS1C1 1 0.02 1.15 0.17 22.48
145 INT289630 Binding of CDSN and RS1 1 0.02 1.1 0.17 22.48
146 INT243685 NDUFA2 Negative_regulation of Localization of RELA 1 0.07 0 0.09 21.68
147 INT198653 TNF Positive_regulation of MIF 1 0.15 3.81 1.55 20.56
148 INT243627 Twist1 Regulation of Gene_expression of Ik 1 0.01 0.13 0.34 20.24
149 INT304581 IL4 Positive_regulation of Gene_expression of IGHE 1 0.17 0.35 0.09 20.04
150 INT214593 Binding of FOXC1 and OAP 1 0.01 0.25 0.13 18.48
151 INT214595 Binding of FOXC1 and TIMP1 1 0.02 0.96 0.66 18.00
152 INT281194 Casr Positive_regulation of Positive_regulation of Nr1i2 1 0.27 0 0.13 17.72
153 INT281193 Nr1i2 Positive_regulation of Positive_regulation of Casr 1 0.27 0 0.13 17.72
154 INT199031 Binding of ALB and F2 1 0.05 1.78 0.08 17.56
155 INT183387 Il6 Positive_regulation of Gene_expression of Il10 2 0.19 1.8 0.63 16.40
156 INT262197 Nr1i2 Positive_regulation of Insig1 2 0.23 0 0.12 15.16
157 INT281192 Casr Positive_regulation of Insig1 1 0.23 0 0.12 15.16
158 INT333842 Hnf1a Positive_regulation of Mir194-1 1 0.02 0.18 0 14.08
159 INT333843 Ccne1 Regulation of Regulation of Mir103-2 1 0.06 0 0 11.76
160 INT337292 STAT3 Negative_regulation of Gene_expression of PTAFR 1 0.27 0.3 0 7.36
161 INT337301 STAT3 Negative_regulation of Gene_expression of TLR4 1 0.33 0 0 7.36
162 INT254223 Tlr3 Positive_regulation of Myd88 1 0.16 0.23 0.08 5.36
163 INT149117 Binding of CD80 and CTLA4 31 0.52 12.7 7.73 5.00
164 INT26824 Crh Positive_regulation of Localization of Penk 7 0.54 0.42 6.49 5.00
165 INT155484 Binding of CD86 and CTLA4 15 0.52 8.85 6.09 5.00
166 INT101942 Binding of CD40 and CD40LG 16 0.23 15.24 4.01 5.00
167 INT69032 IL18 Positive_regulation of IFNA1 12 0.23 7.87 3.83 5.00
168 INT85743 Pdyn Positive_regulation of Oprk1 3 0.32 2.12 3.52 5.00
169 INT180984 IRF6 Positive_regulation of Localization of IL8 7 0.11 2.13 3.47 5.00
170 INT152035 Binding of HLA-A and MRAP 2 0.31 6.95 3.4 5.00
171 INT194647 Binding of CD28 and CD80 15 0.40 4.9 3.22 5.00
172 INT186126 Binding of CD28 and CTLA4 9 0.52 4.13 3.12 5.00
173 INT130721 Binding of IL1B and IL1RN 6 0.05 5.29 2.85 5.00
174 INT175329 Binding of ICAM1 and ITGAL 14 0.18 10.06 2.81 5.00
175 INT69030 IL18 Positive_regulation of IL12A 3 0.31 5.57 2.72 5.00
176 INT114134 Penk Positive_regulation of Oprm1 2 0.24 1.48 2.68 5.00
177 INT122163 Binding of TNF and TNFRSF1B 6 0.44 6.06 2.41 5.00
178 INT239037 Binding of Cd28 and Cd86 9 0.16 3.69 2.14 5.00
179 INT217042 IRF6 Positive_regulation of TNF 4 0.27 3.03 1.95 5.00
180 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87 5.00
181 INT199486 Oprm1 Regulation of Gene_expression of Oprd1 1 0.02 0.49 1.84 5.00
182 INT199287 TNF Positive_regulation of Transcription of Oprm1 2 0.02 1.86 1.8 5.00
183 INT199503 ENG Positive_regulation of Oprk1 1 0.01 0.87 1.69 5.00
184 INT199504 ENG Positive_regulation of Oprm1 1 0.01 0.87 1.68 5.00
185 INT199497 Pdyn Negative_regulation of Il1 1 0.00 0.14 1.67 5.00
186 INT172047 Binding of HLA-A and LRRC23 1 0.22 3.32 1.64 5.00
187 INT199490 Penk Positive_regulation of Oprk1 1 0.03 0.87 1.64 5.00
188 INT199501 Pdyn Positive_regulation of Oprm1 1 0.01 0.86 1.63 5.00
189 INT182097 Binding of Il6 and Il1 4 0.07 4.67 1.55 5.00
190 INT254205 Binding of Myd88 and Tlr4 12 0.19 3.17 1.54 5.00
191 INT252633 Binding of TNF and Tnfrsf1b 4 0.05 3.66 1.54 5.00
192 INT69031 IL12A Positive_regulation of IFNA1 9 0.13 4.23 1.52 5.00
193 INT285569 TNF Negative_regulation of Gene_expression of Il6 1 0.03 2.83 1.46 5.00
194 INT199494 Crh Positive_regulation of Localization of Pdyn 1 0.02 0.43 1.4 5.00
195 INT15846 Crh Positive_regulation of Localization of ENG 3 0.07 0.42 1.38 5.00
196 INT176368 IL18 Positive_regulation of Gene_expression of IFNA1 1 0.16 2.53 1.35 5.00
197 INT265213 Binding of Ctla4 and Cd86 2 0.13 1.93 1.31 5.00
198 INT194513 Timp1 Negative_regulation of Cpox 1 0.00 0.9 1.31 5.00
199 INT113844 CDKN1A Negative_regulation of CDK2 4 0.49 1.18 1.27 5.00
200 INT254210 Binding of Cxcr2 and Ccl2 1 0.08 2.39 1.25 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Crohn's disease. They are ordered first by their pain relevance and then by number of times they were reported in Crohn's disease. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT244512 Positive_regulation of Gene_expression of HSP90B1 2 0.30 12.08 3.12 100.00
2 INT103910 Binding of NOD2 19 0.47 12.24 2.93 100.00
3 INT213886 Binding of IL23R 7 0.46 16.79 6.94 100.00
4 INT181405 Gene_expression of Ccl20 26 0.65 23.02 9.46 100.00
5 INT25356 Positive_regulation of S100A12 18 0.69 17.62 3.38 100.00
6 INT252285 Positive_regulation of Gene_expression of Ccl20 3 0.33 4.01 2.05 100.00
7 INT300540 Positive_regulation of Gene_expression of Ccr6 2 0.55 3.75 1.53 100.00
8 INT117622 Positive_regulation of HSP90B1 3 0.43 4.84 1.02 100.00
9 INT275648 Positive_regulation of Gene_expression of RNF138 1 0.28 2.37 0.6 100.00
10 INT54473 Binding of ABCB1 30 0.48 8.65 10.38 100.00
11 INT275638 Positive_regulation of Gene_expression of STEAP3 1 0.42 2.37 0.6 100.00
12 INT275637 Positive_regulation of Gene_expression of MT2A 2 0.28 2.49 0.6 100.00
13 INT198616 Gene_expression of Gvhd1 6 0.50 8.06 0.67 100.00
14 INT139533 Binding of Il23r 17 0.47 7.67 4.14 100.00
15 INT101412 Negative_regulation of CDAN1 16 0.57 6.41 1.61 100.00
16 INT1878 Binding of HLA-B 440 0.48 321.16 127.36 100.00
17 INT275632 Regulation of Gvhd1 1 0.00 1.59 0.3 100.00
18 INT64157 Positive_regulation of EPCAM 11 0.44 9.09 4.24 100.00
19 INT340345 Positive_regulation of Gene_expression of S100A12 1 0.46 1.94 0.34 100.00
20 INT159493 Binding of CDAN1 3 0.36 2.18 0.62 100.00
21 INT55886 Negative_regulation of Gene_expression of Il4 47 0.57 26.04 11.42 100.00
22 INT8707 Localization of LILRB1 2 0.60 1.5 1.5 100.00
23 INT346896 Binding of Nod2 1 0.21 0.72 0.26 100.00
24 INT72096 Regulation of Positive_regulation of IL4 2 0.20 0.51 0.72 100.00
25 INT76203 Positive_regulation of KRT26 1 0.02 1.34 0.76 100.00
26 INT3459 Positive_regulation of Olfr145 3 0.18 1.34 1.75 100.00
27 INT76210 Positive_regulation of Krt17 1 0.04 1.34 0.76 100.00
28 INT106433 Regulation of CCR5 11 0.59 6.93 2.75 100.00
29 INT181382 Gene_expression of Ccl25 2 0.74 10.94 6.56 99.98
30 INT250993 Gene_expression of FANCE 8 0.48 4.41 0.27 99.98
31 INT103909 Gene_expression of NOD2 37 0.77 21.9 7.36 99.96
32 INT190367 Gene_expression of Defa1 10 0.75 8.92 1.5 99.96
33 INT213501 Negative_regulation of Gene_expression of Defa1 4 0.42 4.74 0.93 99.96
34 INT637 Positive_regulation of MRAP 23 0.67 21.13 9.97 99.96
35 INT154227 Regulation of Gene_expression of NOD2 3 0.44 3.38 0.99 99.96
36 INT156485 Positive_regulation of Gene_expression of CEACAM6 3 0.49 6.5 1.54 99.92
37 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59 99.90
38 INT35028 Positive_regulation of IL2RG 14 0.47 10.05 4.36 99.90
39 INT36052 Positive_regulation of Gene_expression of IL2RG 7 0.28 4.72 2.32 99.90
40 INT135411 Gene_expression of Il23a 76 0.72 72.87 26.15 99.88
41 INT182334 Binding of Glrb 3 0.28 4.81 1.71 99.88
42 INT205714 Positive_regulation of Gene_expression of Pyy 1 0.08 0.92 0.41 99.88
43 INT27325 Positive_regulation of Pyy 15 0.62 13.69 6.54 99.88
44 INT181817 Negative_regulation of Gene_expression of Ppara 58 0.58 43.24 7.67 99.86
45 INT244490 Gene_expression of HSP90B1 4 0.33 41.16 10.37 99.84
46 INT14281 Gene_expression of Hspa5 44 0.63 34.19 3.31 99.84
47 INT148892 Binding of HPS1 13 0.37 19.21 3.35 99.84
48 INT67373 Regulation of Gene_expression of Mefv 2 0.39 6.28 0.75 99.84
49 INT50006 Regulation of HLA-E 12 0.44 8.78 2.37 99.84
50 INT66029 Negative_regulation of Tnf 100 0.59 84.28 48.16 99.84
51 INT137415 Regulation of Gene_expression of SDC1 2 0.02 2.53 0.4 99.84
52 INT183240 Negative_regulation of NOD2 6 0.43 1.52 0.33 99.84
53 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18 99.82
54 INT14731 Positive_regulation of TGFB1 78 0.67 52.57 22.23 99.82
55 INT224648 Gene_expression of Il21 15 0.39 18.71 7.47 99.80
56 INT150022 Positive_regulation of Il17a 69 0.64 70.04 21.87 99.80
57 INT92260 Binding of Nlrp3 14 0.46 8.94 2.13 99.80
58 INT300539 Gene_expression of Rorc 2 0.47 5.8 2 99.80
59 INT296054 Positive_regulation of Il22 13 0.33 17.97 4.06 99.80
60 INT15584 Binding of S100A12 14 0.48 15.14 3 99.80
61 INT182667 Binding of DLAT 11 0.31 40.75 2.8 99.80
62 INT222005 Regulation of HPS1 2 0.33 3.3 0.6 99.80
63 INT144402 Binding of DLG5 4 0.36 3.94 1.24 99.80
64 INT108325 Gene_expression of Scrib 26 0.39 48.33 1.39 99.80
65 INT5374 Gene_expression of Esr1 412 0.77 263.89 67.34 99.76
66 INT1901 Binding of Mefv 24 0.48 32.26 4.5 99.76
67 INT275647 Binding of IBD5 1 0.14 1.81 0.44 99.76
68 INT121818 Binding of STAT3 25 0.47 11.16 3.67 99.76
69 INT271501 Binding of Tnfsf15 1 0.35 1.13 0.42 99.76
70 INT2683 Binding of SGSM3 6 0.36 7.98 1.2 99.76
71 INT151039 Binding of Il23r 8 0.42 3.01 1.86 99.76
72 INT226450 Binding of IL26 4 0.18 1.81 0.93 99.76
73 INT181374 Binding of Ccr6 2 0.29 1.51 0.56 99.76
74 INT186277 Binding of Il12b 4 0.20 2.15 0.55 99.76
75 INT184062 Binding of Jak2 5 0.37 3.13 0.47 99.76
76 INT35460 Gene_expression of IL16 45 0.75 48.71 10.5 99.74
77 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 99.72
78 INT177997 Regulation of SLC22A4 2 0.20 3.88 0.86 99.72
79 INT169180 Binding of SNRNP70 204 0.47 119.1 29.3 99.72
80 INT162793 Regulation of NOD2 6 0.45 7.61 1.78 99.72
81 INT101411 Negative_regulation of IL11 4 0.43 1.16 0.75 99.72
82 INT246029 Regulation of IL23R 1 0.21 2.83 0.35 99.72
83 INT246027 Regulation of ATG16L1 1 0.24 2.82 0.35 99.72
84 INT145077 Regulation of SLC22A5 2 0.19 3 1.1 99.72
85 INT346897 Positive_regulation of Atg16l1 1 0.16 0.57 0.19 99.72
86 INT61075 Gene_expression of PMP2 23 0.61 7.42 2.79 99.70
87 INT115386 Gene_expression of Ppara 779 0.77 549.99 128.36 99.70
88 INT67374 Gene_expression of Mefv 15 0.74 49.1 8.07 99.68
89 INT97514 Positive_regulation of Gene_expression of Mefv 2 0.47 10.98 1.97 99.68
90 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99 99.68
91 INT308527 Regulation of Gene_expression of HSP90B1 2 0.26 5.31 1.46 99.66
92 INT353935 Transcription of Rorc 1 0.48 3.54 0.93 99.64
93 INT20374 Gene_expression of Il4 515 0.76 306.15 114.12 99.64
94 INT73502 Positive_regulation of IL10 154 0.69 124.87 43.5 99.64
95 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92 99.64
96 INT56301 Positive_regulation of IL4 68 0.56 54.51 18.65 99.64
97 INT152254 Gene_expression of CSF1R 16 0.75 12.93 3.81 99.62
98 INT178002 Positive_regulation of CSF1R 2 0.37 6.52 2.74 99.62
99 INT178000 Positive_regulation of Gene_expression of CSF1R 1 0.46 0.85 0.46 99.62
100 INT285 Positive_regulation of Salpa1 73 0.68 61.47 9.19 99.62
101 INT3971 Positive_regulation of Alb 175 0.70 98.46 36.45 99.62
102 INT9660 Regulation of TNF 363 0.62 312.94 139.99 99.60
103 INT117219 Positive_regulation of NOD2 9 0.69 4.66 1.31 99.58
104 INT80036 Positive_regulation of FAS 42 0.67 42.22 9.4 99.58
105 INT6481 Binding of TNF 624 0.48 510.2 214.82 99.56
106 INT142162 Binding of IL10 30 0.37 21.9 4.84 99.56
107 INT285114 Gene_expression of SLC10A7 1 0.25 2.36 0.82 99.56
108 INT250482 Transcription of CMBL 1 0.01 1.19 0.23 99.56
109 INT25991 Negative_regulation of Vip 11 0.53 6.76 4.64 99.56
110 INT99020 Gene_expression of Nlrp3 23 0.75 18.86 4.4 99.54
111 INT83837 Gene_expression of CEACAM6 7 0.76 13.8 4.59 99.54
112 INT65659 Positive_regulation of STAT3 132 0.70 69.56 15.95 99.52
113 INT204766 Gene_expression of Nod2 4 0.75 4.14 1.3 99.52
114 INT27628 Gene_expression of IL2RG 28 0.75 20.95 6.16 99.50
115 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 99.50
116 INT117221 Positive_regulation of Gene_expression of NOD2 7 0.65 4.39 1.83 99.50
117 INT20375 Gene_expression of Hand1 213 0.60 148.51 54.53 99.48
118 INT13354 Transcription of TNF 108 0.72 85.81 42.32 99.48
119 INT49490 Positive_regulation of Transcription of TNF 19 0.70 14.76 7.58 99.48
120 INT275649 Regulation of RNF138 1 0.25 1.49 0.4 99.48
121 INT116980 Positive_regulation of CCL20 5 0.70 4.8 1.02 99.48
122 INT145328 Negative_regulation of Scrib 25 0.16 26.79 2.66 99.48
123 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 99.46
124 INT177998 Binding of RUNX1 7 0.35 7.12 2.08 99.40
125 INT157342 Gene_expression of S100A9 19 0.60 21.27 3.37 99.40
126 INT177989 Negative_regulation of Binding of RUNX1 1 0.21 0.94 0.25 99.40
127 INT50050 Gene_expression of CSRP1 23 0.76 16.84 5.86 99.38
128 INT51817 Gene_expression of Pyy 5 0.65 1.4 1.25 99.38
129 INT13186 Positive_regulation of Il4 113 0.68 71.22 31.4 99.36
130 INT181591 Binding of SLC11A1 1 0.36 1.64 0.24 99.36
131 INT301995 Regulation of Cdh1 5 0.44 3.8 0.48 99.34
132 INT117687 Positive_regulation of TPSD1 5 0.44 2.63 0.46 99.34
133 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58 99.32
134 INT160564 Gene_expression of Il22 64 0.55 59.29 20.9 99.32
135 INT150023 Positive_regulation of Il23a 25 0.38 18.33 6.32 99.32
136 INT282380 Binding of Atg16l1 4 0.38 2.06 0.58 99.32
137 INT282385 Binding of Irgm1 2 0.20 3.18 0.7 99.32
138 INT6489 Positive_regulation of Gene_expression of Tnf 140 0.70 92.31 67.85 99.32
139 INT285489 Positive_regulation of Gene_expression of Il22 9 0.32 10.97 3.63 99.32
140 INT181344 Gene_expression of Ccr6 28 0.61 24.34 9.78 99.28
141 INT2336 Negative_regulation of Lct 51 0.58 33.79 13.73 99.28
142 INT213502 Negative_regulation of Defa1 2 0.02 1.97 0.41 99.28
143 INT322286 Localization of CEACAM6 2 0.41 2.3 0.57 99.28
144 INT61548 Positive_regulation of Fgf2 72 0.70 32.18 14.49 99.28
145 INT28815 Gene_expression of Ighd 18 0.65 11.02 2.48 99.28
146 INT75540 Positive_regulation of TH1L 62 0.67 43.45 15.02 99.28
147 INT350632 Positive_regulation of Il17f 2 0.29 6.22 1.96 99.24
148 INT43997 Positive_regulation of Gene_expression of Esr1 57 0.51 36.66 5.51 99.24
149 INT16068 Gene_expression of SERPINB1 27 0.60 20.51 6.56 99.24
150 INT346908 Negative_regulation of DEFA5 1 0.03 0.41 0.11 99.22
151 INT177992 Positive_regulation of SNRNP70 28 0.49 16.14 4.28 99.20
152 INT8534 Localization of Pax3 85 0.59 28.71 82.82 99.20
153 INT215363 Regulation of HSPD1 4 0.51 2.74 0.99 99.18
154 INT134795 Positive_regulation of Scrib 30 0.22 36.91 2.81 99.16
155 INT108978 Positive_regulation of CUX1 16 0.57 5.93 1.73 99.16
156 INT125447 Positive_regulation of CLDN4 14 0.70 4.71 4.45 99.16
157 INT125446 Negative_regulation of Positive_regulation of CLDN4 2 0.59 2.14 1.3 99.16
158 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 99.12
159 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 99.12
160 INT17326 Binding of Plg 14 0.43 11.72 1.94 99.12
161 INT5058 Positive_regulation of IFNA1 356 0.70 245.75 60.52 99.08
162 INT308149 Gene_expression of Slc22a5 1 0.63 2.77 0.25 99.08
163 INT308147 Gene_expression of Slc22a4 1 0.33 1.55 0.17 99.08
164 INT178004 Binding of SLC22A4 2 0.26 2.45 0.77 99.04
165 INT7678 Localization of Alb 142 0.81 80.93 22.49 99.04
166 INT87470 Gene_expression of SDC1 27 0.78 24.86 5.81 99.00
167 INT222742 Regulation of S100A12 4 0.53 12.09 3.03 99.00
168 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 99.00
169 INT107107 Gene_expression of DEFA1 4 0.01 3.37 1 99.00
170 INT262877 Negative_regulation of Gene_expression of DEFA1 1 0.01 0.92 0.19 99.00
171 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 98.96
172 INT219135 Positive_regulation of Gene_expression of Nlrp3 4 0.49 3.52 0.93 98.96
173 INT341595 Transcription of ORMDL3 1 0.65 1.4 0.92 98.96
174 INT27651 Gene_expression of S100A12 45 0.76 52.25 10.51 98.92
175 INT5609 Regulation of Ifx 6 0.60 5.73 3.5 98.92
176 INT238636 Regulation of Ada 2 0.15 1.12 1.06 98.92
177 INT19330 Binding of HLA-A 99 0.48 76.26 22.85 98.90
178 INT118381 Gene_expression of Il17a 405 0.76 306.97 112.06 98.88
179 INT159494 Gene_expression of CDAN1 8 0.65 4.55 0.58 98.88
180 INT275640 Negative_regulation of Negative_regulation of RNF138 1 0.24 0.98 0.18 98.86
181 INT154334 Localization of S100A12 9 0.80 9.32 2.89 98.84
182 INT10870 Regulation of IgG 67 0.59 43.27 12.74 98.84
183 INT90364 Positive_regulation of Gene_expression of SDC1 3 0.70 2.59 0.83 98.80
184 INT342506 Localization of HSP90B1 1 0.34 0.73 0.22 98.80
185 INT251636 Gene_expression of Csf2rb2 1 0.33 9.64 8.34 98.80
186 INT152433 Binding of CSF1R 6 0.33 10.97 5.54 98.72
187 INT290394 Negative_regulation of Positive_regulation of TLR2 4 0.34 2.8 0.65 98.70
188 INT46383 Negative_regulation of TRGC1 42 0.55 44.03 6.2 98.68
189 INT191457 Regulation of Negative_regulation of DHPS 1 0.16 1.16 0.05 98.68
190 INT191430 Regulation of Negative_regulation of Cndp1 1 0.44 1.16 0.05 98.68
191 INT121942 Binding of Nr1i2 2 0.45 15.69 3.66 98.66
192 INT8232 Gene_expression of Paf 21 0.67 22.18 12.8 98.64
193 INT136993 Positive_regulation of KCNJ2 3 0.35 3.61 2.42 98.62
194 INT246028 Positive_regulation of IL23R 3 0.46 2.74 1.15 98.60
195 INT219247 Positive_regulation of Ddx41 9 0.36 6.7 0.84 98.60
196 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 98.56
197 INT97513 Localization of Mefv 6 0.71 8.14 1.55 98.56
198 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 98.56
199 INT12838 Gene_expression of SIGMAR1 30 0.78 3.52 6.81 98.56
200 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74 98.52
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