P:Delta opioid receptors

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pChart

Pain Term
Category Family
Synonyms Delta-opioid Receptors
Pain Specific No
Documents 1135
Hot Single Events 200
Hot Interactions 101

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Delta opioid receptors. They are ordered first by their pain relevance and then by number of times they were reported for Delta opioid receptors. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT96765 LBR Positive_regulation of Gene_expression of TP53INP2 1 0.11 0.5 0.62 100.00
2 INT21276 Binding of Oprd1 and Penk 9 0.54 1.14 8.28 100.00
3 INT68071 Binding of Tic1 and Rbm39 1 0.01 2.54 1.33 100.00
4 INT9546 Binding of Adarb1 and Penk 5 0.03 0 5.1 100.00
5 INT56859 Oprd1 Positive_regulation of OPRD1 1 0.01 0.22 0.61 100.00
6 INT57546 Binding of YY1 and GNPTAB 1 0.00 0 0.53 100.00
7 INT30042 Binding of YY1 and Gnrhr 1 0.18 0 1.47 100.00
8 INT79206 Binding of MGP and YY1 1 0.34 0 0.19 100.00
9 INT59518 YY1 Positive_regulation of SGCG 1 0.50 0.32 0.99 100.00
10 INT90067 Binding of Oprd1 and Npff 1 0.20 0.09 0.52 100.00
11 INT61346 Positive_regulation of YY1 Positive_regulation of Localization of SST 1 0.54 0 0.22 100.00
12 INT34006 Binding of ITPR3 and YY1 1 0.22 0.33 0.48 100.00
13 INT34005 YY1 Regulation of KNG1 1 0.04 0.38 0.63 100.00
14 INT8330 OPRD1 Regulation of Localization of GH1 1 0.19 0.17 0.33 100.00
15 INT29240 Binding of POMC and YY1 5 0.40 0.17 4.06 100.00
16 INT154114 PENK Positive_regulation of YY1 1 0.50 0.06 1.41 100.00
17 INT154113 POMC Positive_regulation of YY1 1 0.70 0.06 1.41 100.00
18 INT109380 Binding of Adarb1 and Fos 1 0.02 0.38 1.19 100.00
19 INT73075 Adarb1 Regulation of Fos 1 0.01 0.07 1.18 100.00
20 INT69338 Binding of Oprd1 and Oprm1 1 0.24 0.26 1.11 100.00
21 INT118204 ST14 Regulation of YY1 1 0.04 0 0.93 100.00
22 INT61050 Oprd1 Positive_regulation of Odc1 1 0.25 0 0.74 100.00
23 INT115764 Binding of Rbm39 and Tat 1 0.00 0 0.66 100.00
24 INT74656 YY1 Positive_regulation of Localization of IL2 1 0.07 0.09 0.58 100.00
25 INT70288 Negative_regulation of Atxn2l Positive_regulation of Racgap1 1 0.02 0.3 1.19 99.92
26 INT70289 Atxn2l Positive_regulation of Racgap1 1 0.04 0.29 1.15 99.92
27 INT117707 Oprm1 Positive_regulation of PIK3CG 1 0.00 0.08 0.6 99.88
28 INT57555 Binding of Oprm1 and Oprl1 2 0.06 0.05 0.97 99.56
29 INT154111 POMC Positive_regulation of Localization of PENK 1 0.34 0.05 1.41 99.48
30 INT154110 PENK Positive_regulation of Localization of POMC 1 0.34 0.05 1.41 99.48
31 INT133617 Fas Positive_regulation of Fadd 1 0.48 0.07 0.96 99.40
32 INT8735 Oprm1 Positive_regulation of Scn4a 1 0.00 0 1.49 99.32
33 INT6657 Binding of POMC and D15Mit108 1 0.03 0.49 0.37 99.04
34 INT162954 Sema6a Regulation of Scn7a 1 0.10 0.55 0.46 98.96
35 INT165450 Gal Regulation of Ceacam3 1 0.41 0.06 1.47 98.92
36 INT72325 Binding of Sigmar1 and WWOX 1 0.26 0 0.18 98.88
37 INT29380 Binding of gp and Mme 1 0.01 0 0.71 98.32
38 INT110458 Binding of Atf2 and Mapk8 1 0.35 0 0.66 98.28
39 INT76154 Binding of NCOR2 and Negative_regulation of Localization of PLOD1 1 0.02 0 0.42 98.24
40 INT76153 Binding of NCOR2 and Negative_regulation of Localization of LHB 1 0.00 0 0.42 98.24
41 INT92444 Cpe Negative_regulation of Phosphorylation of Cd3eap 1 0.01 0 0.34 97.68
42 INT69337 Oprm1 Positive_regulation of Atxn2l 1 0.01 0.27 1.43 97.64
43 INT64744 OR5D2P Negative_regulation of ADCY1 1 0.00 0 0.54 97.40
44 INT20929 Binding of Trim13 and Vas1 1 0.10 0 1.18 96.70
45 INT34393 Oprd1 Negative_regulation of Adcy1 1 0.36 0 1.27 96.24
46 INT6466 Binding of Npr1 and Oprd1 1 0.01 0 1.37 96.12
47 INT64382 Positive_regulation of Binding of YY1 and Tyr 1 0.11 0 0.21 96.04
48 INT64383 Binding of YY1 and Tyr 1 0.09 0 0.21 96.04
49 INT126304 Binding of Rgs2 and Pag1 1 0.16 0.41 0.72 95.80
50 INT126303 Binding of Rgs7 and Pag1 1 0.15 0.41 0.72 95.56
51 INT126305 Binding of Rgs10 and Pag1 1 0.16 0.41 0.72 95.32
52 INT126306 Binding of Rgs11 and Pag1 1 0.18 0.41 0.72 94.92
53 INT94034 SLAMF6 Regulation of Binding of Adarb1 and SLAMF6 1 0.00 0 0.39 94.20
54 INT8331 OPRD1 Regulation of Localization of GHRH 1 0.18 0.18 0.37 94.16
55 INT94033 Binding of Adarb1 and SLAMF6 1 0.01 0 1.61 93.76
56 INT110464 Cpe Regulation of Phosphorylation of Atf2 1 0.02 0 0.32 93.32
57 INT110472 Cpe Regulation of Binding of Mapk8 and Gtf3a 1 0.00 0 0.32 93.32
58 INT110471 Cpe Regulation of Binding of Atf2 and Jun 1 0.02 0 0.32 93.32
59 INT110470 Cpe Regulation of Binding of Atf2 and Mapk8 1 0.02 0 0.32 93.32
60 INT110462 Cpe Regulation of Phosphorylation of Gtf3a 1 0.00 0 0.32 93.32
61 INT7025 Positive_regulation of Drd1a Positive_regulation of Npr1 1 0.04 0.08 1.01 93.20
62 INT59687 Gene_expression of Opcml Regulation of Binding of Oprd1 1 0.00 0.54 0.62 93.12
63 INT72849 RT1-EC2 Positive_regulation of Adrbk1 1 0.01 0.33 0.1 92.80
64 INT72848 RT1-EC2 Positive_regulation of Adrbk2 1 0.00 0.33 0.1 92.80
65 INT72847 Adrbk2 Positive_regulation of Adrbk1 1 0.02 0.33 0.1 92.80
66 INT123451 Binding of YY1 and Adra2a 1 0.37 0 2.98 91.64
67 INT52383 Binding of Gs and Ptprg 1 0.00 0.48 0.44 91.64
68 INT82040 Adora2a Positive_regulation of Phosphorylation of Ppp1r1b 1 0.11 0 0.75 91.44
69 INT82039 Akr1d1 Positive_regulation of Phosphorylation of Ppp1r1b 1 0.02 0 0.74 90.88
70 INT7022 Drd1a Positive_regulation of Npr1 6 0.05 0.26 4.32 90.40
71 INT7023 Negative_regulation of Drd1a Positive_regulation of Npr1 2 0.05 0.1 1.81 90.40
72 INT110461 Binding of Mapk8 and Gtf3a 1 0.03 0 0.32 90.32
73 INT110463 Binding of Jun and Gtf3a 1 0.04 0 0.32 90.32
74 INT264950 Binding of FPR1 and BOC 1 0.11 0.67 1.55 90.04
75 INT264943 Negative_regulation of Binding of FPR1 and BOC 1 0.13 0.22 0.64 90.04
76 INT264952 Binding of GOPC and BOC 1 0.05 0.22 0.64 90.04
77 INT110459 Binding of Atf2 and Jun 1 0.32 0 0.31 90.00
78 INT190981 Binding of Npy and Scn2a1 1 0.10 0 1.75 89.88
79 INT116628 St13 Regulation of Positive_regulation of P9Ehs1 1 0.00 0 1.25 89.36
80 INT14626 Binding of Dpep1 and Pax3 1 0.01 0 0.87 89.08
81 INT182704 Binding of NPFF and TP53INP2 1 0.01 0.73 3.28 89.04
82 INT264946 Binding of FPR1 and GOPC 1 0.08 0.21 0.64 88.64
83 INT70010 Binding of Neurod1 and Insrr 1 0.01 0.11 0.37 88.56
84 INT70009 Binding of Gabpb1 and Insrr 1 0.00 0.11 0.37 88.56
85 INT82194 Dbi Regulation of Oprd1 1 0.12 0.07 0.26 87.76
86 INT67663 Ins1 Positive_regulation of Ntrk2 1 0.00 0.19 2.59 87.68
87 INT61049 Binding of Oprd1 and Negative_regulation of Gene_expression of Odc1 1 0.21 0 1.64 87.12
88 INT77689 Binding of Ace and Tenc1 1 0.28 0.65 0.7 86.68
89 INT142868 YY1 Positive_regulation of Oprd1 1 0.01 0.1 0.55 86.00
90 INT83967 Binding of MGP and OPRD1 1 0.16 0 0.29 84.28
91 INT6464 Sst Regulation of Negative_regulation of Npr1 1 0.01 0 0.64 84.24
92 INT108197 AKT1 Regulation of JUN 1 0.29 0.25 0.4 83.60
93 INT6463 Oprd1 Regulation of Negative_regulation of Npr1 1 0.01 0 0.63 83.28
94 INT7024 Regulation of Drd1a Positive_regulation of Npr1 1 0.04 0.07 1.13 82.80
95 INT94473 Binding of Cd3e and Trav6-3 2 0.05 0 0.34 82.52
96 INT94474 Binding of Cd3e and Il27ra 1 0.02 0 0.34 82.52
97 INT6465 Trh Regulation of Negative_regulation of Npr1 1 0.01 0 0.63 82.20
98 INT61052 Binding of Adarb1 and Negative_regulation of Gene_expression of Odc1 1 0.02 0 0.81 80.96
99 INT77394 Binding of ARRB1 and GIPC1 1 0.01 0 0.56 80.88
100 INT75992 Binding of Pvalb and Lgals3 1 0.00 0 0.56 80.32
101 INT111265 Binding of Gnb5 and Ggt5 1 0.52 0.07 0.37 80.16
102 INT82041 Positive_regulation of Adora2a Positive_regulation of Phosphorylation of Ppp1r1b 1 0.12 0 0.72 79.84
103 INT111266 Binding of Gnb5 and Bscl2 1 0.14 0.06 0.37 79.76
104 INT145407 Oprd1 Regulation of Positive_regulation of Dbi 1 0.17 0 1.07 77.44
105 INT61046 Oprm1 Positive_regulation of Gh1 1 0.21 0 0.89 76.96
106 INT61047 Oprm1 Positive_regulation of Localization of Gh1 1 0.29 0 0.89 76.96
107 INT61048 Oprm1 Positive_regulation of Localization of Prl 1 0.16 0 0.88 76.68
108 INT61045 Oprm1 Positive_regulation of Prl 1 0.16 0 0.88 76.68
109 INT29382 Positive_regulation of gp Regulation of Mme 1 0.02 0 0.65 76.16
110 INT69178 Binding of SLC3A2 and Adarb1 1 0.00 0.16 0.53 75.88
111 INT29381 gp Regulation of Mme 1 0.01 0 0.65 75.72
112 INT59707 PSENEN Regulation of Negative_regulation of YY1 1 0.12 0.07 1.21 75.00
113 INT148909 Binding of GNA13 and TP53INP2 1 0.06 0.31 0.73 75.00
114 INT29093 Binding of H2-Ab1 and Rbm39 1 0.06 0 1.5 75.00
115 INT129640 Binding of Ambp and Oprd1 1 0.22 0.19 0.55 75.00
116 INT129639 Regulation of Binding of Ambp and Oprd1 1 0.17 0.19 0.55 75.00
117 INT77924 Binding of SCD and Oprd1 1 0.00 0.25 0.4 75.00
118 INT18270 Binding of Oprd1 and Pomc 1 0.30 0 0.4 75.00
119 INT77923 Negative_regulation of Binding of SCD and Oprd1 1 0.00 0.25 0.4 75.00
120 INT26193 OPRD1 Positive_regulation of MET 1 0.47 0 0.33 75.00
121 INT114756 Binding of OPRD1 and Penk 1 0.01 0 0.3 75.00
122 INT114757 Negative_regulation of Binding of OPRD1 and Penk 1 0.01 0 0.3 75.00
123 INT56892 Binding of MGP and Oprd1 1 0.05 0 0.27 75.00
124 INT16811 Binding of Scd1 and Oprl1 1 0.00 0 0.24 75.00
125 INT25907 Binding of PRLR and Cish 1 0.00 0 0.23 75.00
126 INT69179 Binding of UBA7 and Adarb1 1 0.00 0.16 0.53 74.88
127 INT56779 Pomc Negative_regulation of Gene_expression of Odc1 2 0.31 0 0.89 73.76
128 INT151485 Negative_regulation of Binding of Ptpn6 and Oprd1 1 0.00 0 0.47 72.56
129 INT151484 Binding of Ptpn6 and Oprd1 1 0.00 0 0.47 72.56
130 INT151483 Negative_regulation of Binding of Oprd1 and Penk 1 0.02 0 0.47 72.56
131 INT69177 UBA7 Negative_regulation of Igk 1 0.00 0.15 0.54 70.32
132 INT79094 PDYN Positive_regulation of PRL 1 0.35 0.09 1.07 69.76
133 INT317560 Binding of Pdpk1 and Pik3r1 1 0.13 0 0.65 66.96
134 INT125856 Positive_regulation of Oprm1 Regulation of Positive_regulation of Insrr 1 0.01 0.26 1.43 66.92
135 INT82038 Positive_regulation of Akr1d1 Positive_regulation of Phosphorylation of Ppp1r1b 1 0.02 0 0.64 65.68
136 INT70011 Binding of Hrh1 and Insrr 1 0.00 0.4 0.72 65.64
137 INT53052 ANTXRL Negative_regulation of Negative_regulation of ADCY1 1 0.01 0.66 0.99 65.04
138 INT125857 Insrr Negative_regulation of Oprm1 1 0.01 0.27 1.24 63.52
139 INT33976 Trmt2a Negative_regulation of Binding of Fads1 1 0.00 0 0.94 63.12
140 INT60948 Ltp Negative_regulation of Negative_regulation of Gabrd 1 0.02 0.07 1.03 61.76
141 INT7893 Binding of Oprm1 and Ccl21b 1 0.00 0.08 0.35 61.20
142 INT145408 H2-Ab1 Negative_regulation of Gene_expression of Dbi 1 0.05 0 1.06 60.96
143 INT26185 Positive_regulation of Binding of GREM1 and Cyth2 1 0.00 0 0.22 60.60
144 INT26186 Binding of GREM1 and Cyth2 1 0.00 0 0.22 60.20
145 INT103724 Oprd1 Positive_regulation of Gtpbp4 3 0.30 0.91 4.18 59.20
146 INT117703 OPRK1 Positive_regulation of Positive_regulation of JUN 1 0.01 0.08 0.47 58.40
147 INT77393 Binding of ARRB1 and OPRM1 1 0.15 0 0.82 57.64
148 INT264944 Binding of POMC and BOC 1 0.07 0.44 0.89 55.36
149 INT128521 Binding of YY1 and IGKV2-26 1 0.12 0 0.45 54.40
150 INT68527 Binding of ADCY1 and OPRD1 1 0.06 0.07 0.41 51.80
151 INT68526 Binding of ADCY1 and DIO2 1 0.01 0.07 0.41 51.12
152 INT112843 Binding of OPRK1 and Nfatc4 1 0.00 0 0.48 49.68
153 INT29323 Trmt2a Negative_regulation of Binding of Srms 1 0.00 0 0.84 48.08
154 INT29119 Nts Regulation of Oprd1 1 0.18 0.79 0.31 45.04
155 INT29118 Trh Regulation of Oprd1 1 0.24 0.79 0.31 45.04
156 INT8734 Pebp1 Positive_regulation of Oprd1 1 0.01 0 1.54 44.92
157 INT317522 Akt1 Positive_regulation of Phosphorylation of Nos1 1 0.43 0.4 3.13 44.48
158 INT164665 Adarb1 Positive_regulation of Negative_regulation of Tens1 1 0.03 0.42 1.97 43.20
159 INT29324 Trmt2a Negative_regulation of Binding of Pomc 1 0.00 0 0.71 41.44
160 INT133616 Map2k1 Regulation of Fadd 1 0.04 0.29 0.97 39.36
161 INT133614 Map2k1 Regulation of Daxx 1 0.02 0.29 0.97 39.36
162 INT133615 Regulation of Map2k1 Regulation of Fadd 1 0.04 0.29 0.97 39.36
163 INT317563 Binding of Hint1 and Oprm1 1 0.20 0.25 3.03 36.88
164 INT317526 Binding of Hint1 and Gipc1 1 0.00 0.25 2.38 36.88
165 INT98379 Regulation of Binding of Pomc and Oprd1 1 0.01 0.35 0.23 36.24
166 INT98380 Binding of Pomc and Oprd1 1 0.02 0.35 0.23 36.24
167 INT66569 Pomc Positive_regulation of Atxn2l 1 0.03 0 1.36 36.00
168 INT61053 Adarb1 Positive_regulation of Pomc Negative_regulation of Odc1 1 0.01 0 1.1 35.44
169 INT70603 Penk Positive_regulation of Pdyn 1 0.13 0 1.11 32.16
170 INT61051 Pomc Negative_regulation of Odc1 1 0.22 0 0.54 32.16
171 INT5486 Oprd1 Regulation of Cck 1 0.21 0 2.16 31.68
172 INT317533 Akt1 Positive_regulation of Nos1 1 0.43 0 0.28 30.04
173 INT6415 Binding of Cpe and Oprd1 1 0.00 0 1.07 29.36
174 INT12684 Binding of Bcar3 and Trim13 1 0.03 0 1.08 27.76
175 INT7888 Oprl1 Regulation of Localization of Avp 4 0.49 0.25 2.63 25.00
176 INT7887 Oprl1 Regulation of Localization of Oxt 2 0.16 0 1.23 25.00
177 INT112842 Positive_regulation of Binding of Pdyn and Oprd1 1 0.00 0 0.81 25.00
178 INT112841 Binding of Pdyn and Oprd1 1 0.00 0 0.81 25.00
179 INT29241 Binding of OPRD1 and POMC 1 0.09 0 0.22 25.00
180 INT317512 Binding of Oprm1 and Prkca 1 0.07 0.13 1.1 24.08
181 INT264948 BOC Negative_regulation of FPR1 1 0.13 0.18 0.48 20.16
182 INT264949 BOC Negative_regulation of Localization of FPR1 1 0.13 0.18 0.48 20.16
183 INT264975 BOC Negative_regulation of Localization of Oprd1 1 0.01 0.17 0.48 20.16
184 INT317566 Car2 Positive_regulation of Camk2a 2 0.19 0.58 0.32 11.28
185 INT317557 Calm3 Positive_regulation of Car2 1 0.05 0 0.31 11.28
186 INT317545 Calm3 Positive_regulation of Camk2a 1 0.17 0 0.31 11.08
187 INT317521 Camk2a Negative_regulation of Binding of Calm3 1 0.11 0 0.43 9.76
188 INT264945 GOPC Positive_regulation of Positive_regulation of FPR1 1 0.10 0.2 0.44 8.56
189 INT317552 Binding of Calm3 and Car2 2 0.06 0.07 1.05 7.48
190 INT317517 Binding of Nos1 and Oprm1 1 0.17 0.22 3.85 5.00
191 INT317511 Ppp1r9b Regulation of Oprm1 3 0.27 0.33 3.85 5.00
192 INT317551 Binding of Akt1 and Oprm1 1 0.19 0.21 2.74 5.00
193 INT317528 Ppp1r9b Regulation of Grin1 1 0.18 0.2 2.48 5.00
194 INT211748 Binding of Pag1 and Mors1 2 0.07 0.2 2.26 5.00
195 INT317524 Binding of Camk2a and Grin1 1 0.17 0.06 2.21 5.00
196 INT317540 Camk2a Negative_regulation of Oprm1 1 0.19 0 1.98 5.00
197 INT264953 Binding of POMC and TLR4 1 0.03 0.89 1.96 5.00
198 INT264947 Binding of POMC and TLR2 1 0.03 0.89 1.95 5.00
199 INT317558 Binding of Oprm1 and Rgs17 1 0.18 0 1.59 5.00
200 INT182706 NPFF Regulation of Binding of TP53INP2 1 0.01 0.07 1.52 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Delta opioid receptors. They are ordered first by their pain relevance and then by number of times they were reported in Delta opioid receptors. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT53015 Gene_expression of TP53INP2 50 0.78 9.05 26.23 100.00
2 INT6656 Gene_expression of YY1 135 0.75 24.73 72.16 100.00
3 INT5660 Binding of Oprd1 477 0.48 71.86 342.06 100.00
4 INT5979 Gene_expression of Oprd1 428 0.78 75.64 320.32 100.00
5 INT4941 Positive_regulation of Oprd1 345 0.70 74.26 304.41 100.00
6 INT6437 Binding of YY1 154 0.47 26.3 90.46 100.00
7 INT789 Positive_regulation of YY1 69 0.67 14.07 47.06 100.00
8 INT76701 Binding of TP53INP2 13 0.31 0.55 8.13 100.00
9 INT5501 Regulation of Oprd1 283 0.62 55.1 249.9 100.00
10 INT32718 Gene_expression of OPRD1 82 0.76 9.43 48.38 100.00
11 INT7828 Positive_regulation of Oprd1 55 0.69 14.11 42.86 100.00
12 INT76702 Localization of TP53INP2 4 0.47 0.17 2.62 100.00
13 INT12569 Localization of Oprd1 94 0.81 23.81 104.56 100.00
14 INT30386 Negative_regulation of OPRD1 33 0.52 4.34 23.06 100.00
15 INT4937 Negative_regulation of Oprd1 224 0.59 44.51 171.11 100.00
16 INT4637 Binding of Adarb1 132 0.41 14.48 67.76 100.00
17 INT73750 Regulation of Gene_expression of YY1 7 0.44 0.28 3.91 100.00
18 INT10668 Positive_regulation of Gene_expression of Oprd1 61 0.69 15.21 52.12 100.00
19 INT1160 Positive_regulation of Rbm39 122 0.57 28.19 90.28 100.00
20 INT1665 Positive_regulation of Pag1 270 0.68 186.63 229.87 100.00
21 INT12501 Positive_regulation of Adarb1 166 0.58 36.94 118.92 100.00
22 INT5374 Gene_expression of Esr1 412 0.77 263.89 67.34 100.00
23 INT6822 Gene_expression of Pdyn 215 0.78 35.99 125.76 100.00
24 INT6406 Binding of Oprm1 280 0.48 40.54 226.26 100.00
25 INT6066 Negative_regulation of Positive_regulation of Oprd1 15 0.43 1.36 16.63 100.00
26 INT12397 Gene_expression of Oprd1 53 0.78 9.1 31.31 100.00
27 INT5771 Binding of Oprd1 37 0.48 2.6 27.54 100.00
28 INT6934 Binding of OPRD1 51 0.48 7.72 25.73 100.00
29 INT5770 Binding of Rbm39 88 0.41 13.23 55.5 100.00
30 INT6717 Negative_regulation of YY1 45 0.57 15.35 27.8 100.00
31 INT129645 Negative_regulation of Gene_expression of TAC1 5 0.42 3.33 5.55 100.00
32 INT65731 Gene_expression of Cnr1 234 0.78 63.82 109.34 100.00
33 INT5931 Regulation of Oprm1 149 0.62 18.15 125.93 100.00
34 INT33419 Positive_regulation of Gene_expression of YY1 10 0.67 4.15 7.08 100.00
35 INT6214 Negative_regulation of Adarb1 123 0.50 26.39 89.57 100.00
36 INT6067 Positive_regulation of Positive_regulation of Oprd1 37 0.69 6.56 36.58 100.00
37 INT53014 Transcription of TP53INP2 2 0.41 1.05 2.91 100.00
38 INT2197 Gene_expression of Gnrh1 184 0.78 40.04 50.57 100.00
39 INT13290 Binding of Atxn2l 34 0.18 1.86 28.16 100.00
40 INT6165 Gene_expression of Adarb1 85 0.58 18.39 51.03 100.00
41 INT8332 Positive_regulation of OPRD1 30 0.61 3.88 17.65 100.00
42 INT29352 Negative_regulation of Oprd1 16 0.58 6.51 14.6 100.00
43 INT1163 Negative_regulation of Rbm39 64 0.29 16.8 34.74 100.00
44 INT5930 Positive_regulation of Oprm1 221 0.70 31.19 172.93 100.00
45 INT53889 Negative_regulation of Positive_regulation of YY1 6 0.41 0.57 3.05 100.00
46 INT5704 Binding of Slc3a1 78 0.43 8.52 51.78 100.00
47 INT94303 Gene_expression of Upf1 44 0.04 11.62 3.87 100.00
48 INT12416 Regulation of Atxn2l 8 0.07 0.25 7.42 100.00
49 INT1425 Gene_expression of Rbm39 143 0.58 51.32 65.44 100.00
50 INT34465 Regulation of Oprd1 34 0.45 7.14 34.29 100.00
51 INT3359 Regulation of YY1 32 0.60 8.19 19.2 100.00
52 INT43009 Gene_expression of Scn7a 45 0.68 7.85 10.29 100.00
53 INT18647 Localization of YY1 16 0.78 4.04 9.77 100.00
54 INT108726 Binding of Mors1 38 0.33 7.08 43.62 100.00
55 INT39837 Positive_regulation of Cpn1 6 0.69 6.2 2.06 100.00
56 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 100.00
57 INT11279 Positive_regulation of Penk 65 0.70 18.72 30.29 100.00
58 INT83419 Gene_expression of Mors1 57 0.68 12.11 63.66 100.00
59 INT29356 Positive_regulation of Binding of YY1 8 0.67 0.22 3.49 100.00
60 INT114578 Positive_regulation of Gene_expression of Ceacam3 18 0.47 14.95 12.22 100.00
61 INT126001 Positive_regulation of Localization of Olfr749 1 0.61 0.26 1.25 100.00
62 INT126000 Localization of Olfr749 1 0.70 0.26 1.24 100.00
63 INT1429 Gene_expression of PDYN 308 0.78 61.33 175.65 100.00
64 INT6926 Regulation of Pag1 72 0.39 55.79 65.09 100.00
65 INT53891 Positive_regulation of Positive_regulation of YY1 5 0.49 0.24 3.65 100.00
66 INT18755 Positive_regulation of Rvm 79 0.60 60 92.93 100.00
67 INT29802 Localization of Rbm39 18 0.64 4.04 9.84 100.00
68 INT21072 Localization of Adarb1 26 0.69 2.76 17.95 100.00
69 INT14159 Negative_regulation of Positive_regulation of Adarb1 8 0.08 2.06 5.14 100.00
70 INT132682 Phosphorylation of Pag1 7 0.71 5.61 5.75 100.00
71 INT211738 Positive_regulation of Phosphorylation of Pag1 2 0.24 1.3 2.23 100.00
72 INT118206 Negative_regulation of Gene_expression of TP53INP2 1 0.29 1.85 3.39 100.00
73 INT89842 Phosphorylation of Src 34 0.69 9.57 13.08 100.00
74 INT98647 Positive_regulation of Mdk 65 0.59 32.93 15.67 100.00
75 INT104310 Gene_expression of NPFFR1 7 0.75 1.03 3.94 100.00
76 INT49087 Positive_regulation of Rab38 20 0.00 8.01 12 100.00
77 INT647 Gene_expression of SGCG 211 0.75 78.46 55.82 100.00
78 INT89845 Positive_regulation of Src 19 0.44 7.5 9.01 100.00
79 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 100.00
80 INT25647 Negative_regulation of Binding of YY1 10 0.57 1.47 6.77 100.00
81 INT15054 Gene_expression of Mme 48 0.77 42.52 10.63 100.00
82 INT57145 Transcription of OPRD1 6 0.61 0.34 2.99 100.00
83 INT35716 Positive_regulation of NCOR2 45 0.60 18 23.54 100.00
84 INT7829 Negative_regulation of Positive_regulation of Oprd1 2 0.30 0.41 1.95 100.00
85 INT62630 Positive_regulation of CNR1 86 0.70 40.34 51.51 100.00
86 INT12837 Binding of SIGMAR1 57 0.48 5.31 15.49 100.00
87 INT26973 Gene_expression of Tenc1 59 0.66 27.19 12 100.00
88 INT11429 Gene_expression of ADCY1 26 0.74 5.89 11.93 100.00
89 INT31125 Binding of Dpp6 10 0.36 0.22 8.26 100.00
90 INT89844 Positive_regulation of Phosphorylation of Src 10 0.43 4.71 4.95 100.00
91 INT74695 Gene_expression of Ace 41 0.73 53.33 2.33 100.00
92 INT16656 Negative_regulation of Gene_expression of YY1 8 0.57 2.62 2.12 100.00
93 INT79802 Phosphorylation of YY1 2 0.80 0.07 1.7 100.00
94 INT32777 Regulation of Gene_expression of Mettl15 1 0.56 0.2 0.78 100.00
95 INT133685 Positive_regulation of Gene_expression of NPFFR1 1 0.49 0.1 0.58 100.00
96 INT16657 Positive_regulation of Negative_regulation of YY1 1 0.49 0.42 0.55 100.00
97 INT113771 Gene_expression of Asgr1 1 0.44 0.28 0.45 100.00
98 INT77688 Transcription of Mme 2 0.53 4.01 0.45 100.00
99 INT77686 Transcription of Ace 2 0.65 2.65 0.37 100.00
100 INT7833 Positive_regulation of Cck 33 0.70 8.54 34.21 99.98
101 INT7825 Positive_regulation of Localization of Cck 7 0.47 0.89 5.92 99.98
102 INT90014 Gene_expression of RGS4 5 0.78 2.05 6.94 99.98
103 INT67661 Gene_expression of Ncr1 6 0.62 3.89 5.17 99.98
104 INT8379 Regulation of Qrfp 26 0.60 2.56 15.82 99.98
105 INT90184 Gene_expression of KCNJ6 7 0.67 4.14 12.57 99.98
106 INT86698 Gene_expression of Cav1 38 0.78 16.37 11.75 99.98
107 INT20578 Positive_regulation of Gene_expression of Akr1d1 5 0.22 0.26 2.1 99.98
108 INT7823 Negative_regulation of Binding of Cck 2 0.43 0.07 1.69 99.98
109 INT90190 Gene_expression of KCNJ3 3 0.75 0 1.23 99.98
110 INT6042 Binding of Oprm1 248 0.48 31.77 154.34 99.96
111 INT75938 Regulation of TP53INP2 9 0.09 2.45 7.21 99.96
112 INT110447 Regulation of Trav6-3 11 0.15 1.93 1.21 99.96
113 INT21128 Binding of CLMP 1 0.01 0 0.63 99.96
114 INT32778 Gene_expression of Mettl15 6 0.70 0.98 5.86 99.92
115 INT2323 Gene_expression of Trh 146 0.78 29.92 49.5 99.92
116 INT874 Positive_regulation of Gh1 244 0.70 27.17 97.98 99.92
117 INT155 Positive_regulation of Prl 1233 0.70 317.93 457.82 99.92
118 INT148 Positive_regulation of Gnrhr 182 0.70 47.44 79.64 99.92
119 INT7800 Localization of Pag1 51 0.56 33.06 53.74 99.90
120 INT2123 Positive_regulation of Gnrh1 209 0.70 24.2 68.97 99.90
121 INT15622 Positive_regulation of Negative_regulation of Gnrh1 4 0.46 1.13 2.27 99.90
122 INT5851 Positive_regulation of Gene_expression of Penk 52 0.70 14.57 25.05 99.90
123 INT1642 Negative_regulation of Localization of PLOD1 40 0.58 10.67 17.95 99.90
124 INT4207 Regulation of Avp 267 0.62 63.72 115.33 99.88
125 INT1351 Gene_expression of Pag1 131 0.57 89.48 98.76 99.84
126 INT12725 Positive_regulation of Racgap1 66 0.68 32.74 19.29 99.84
127 INT255 Regulation of Localization of GH1 89 0.62 18.71 35.3 99.84
128 INT7396 Regulation of Localization of GNRH1 81 0.62 6.57 31.31 99.84
129 INT7362 Gene_expression of Sst 185 0.78 41.73 111.37 99.84
130 INT5587 Regulation of Fos 191 0.62 40.81 99.7 99.84
131 INT70282 Negative_regulation of Positive_regulation of Ndst4 1 0.01 0.26 1.04 99.82
132 INT2783 Gene_expression of Slc3a1 86 0.65 8.84 45.4 99.80
133 INT5895 Gene_expression of Oprm1 525 0.78 120.67 407.29 99.80
134 INT21502 Gene_expression of Scn4a 22 0.78 4.47 7.97 99.80
135 INT72316 Regulation of Amp1 5 0.07 1.19 0.39 99.80
136 INT106525 Phosphorylation of Akt1 436 0.82 183.81 47.82 99.78
137 INT109304 Positive_regulation of Phosphorylation of Akt1 113 0.69 40.92 13.49 99.78
138 INT7832 Localization of Cck 39 0.81 6.81 26.54 99.78
139 INT1396 Binding of Penk 355 0.48 22.79 269.65 99.76
140 INT20703 Regulation of Scn4a 5 0.35 0.38 5.17 99.76
141 INT3301 Positive_regulation of Slc43a3 26 0.55 5.48 10.81 99.76
142 INT66867 Gene_expression of Ceacam3 58 0.67 30.44 40.7 99.76
143 INT111264 Gene_expression of Rgs9 16 0.76 1.96 10.94 99.76
144 INT111259 Negative_regulation of Gene_expression of Rgs9 3 0.41 0.15 2.96 99.76
145 INT111257 Negative_regulation of Gene_expression of Gnb5 1 0.41 0.15 0.86 99.76
146 INT111263 Gene_expression of Gnb5 8 0.75 8.51 3 99.76
147 INT157 Positive_regulation of Localization of Prl 790 0.70 104.54 374.78 99.74
148 INT2365 Positive_regulation of Cck 354 0.70 87.8 277.41 99.72
149 INT1352 Localization of Acot1 728 0.80 73.01 296.01 99.70
150 INT159 Negative_regulation of Localization of Prl 416 0.59 55.34 171.8 99.68
151 INT439 Localization of Gnrh1 976 0.81 100.96 363.25 99.66
152 INT20575 Gene_expression of Akr1d1 48 0.57 6.2 22.5 99.66
153 INT1395 Negative_regulation of Penk 537 0.59 87.33 389.81 99.64
154 INT96913 Positive_regulation of Mapk8 179 0.69 130.44 32.2 99.64
155 INT99592 Regulation of Adrbk1 3 0.61 1.46 2.84 99.64
156 INT5852 Gene_expression of Penk 167 0.78 44.44 71.13 99.62
157 INT1562 Localization of Crh 499 0.81 126.74 236.68 99.60
158 INT5509 Positive_regulation of Localization of Crh 91 0.70 30.65 53.92 99.60
159 INT158 Localization of Prl 2431 0.81 378.96 952.2 99.58
160 INT5959 Protein_catabolism of Cpe 17 0.90 0.98 12.43 99.58
161 INT876 Localization of Gh1 843 0.80 67.75 340.82 99.58
162 INT7827 Binding of Cck 32 0.48 4.66 23.73 99.58
163 INT92435 Phosphorylation of Setbp1 1 0.46 0 0.26 99.58
164 INT767 Localization of Gnrhr 565 0.80 106.68 214.57 99.58
165 INT917 Positive_regulation of Localization of PLOD1 51 0.69 8.53 22.87 99.58
166 INT12575 Regulation of Hpse 33 0.59 17.7 18.45 99.58
167 INT77406 Negative_regulation of Negative_regulation of ARRB1 1 0.47 0 0.71 99.58
168 INT249 Localization of GHRH 215 0.80 78.02 51.87 99.56
169 INT695 Binding of POMC 304 0.48 56.66 126.85 99.52
170 INT2366 Binding of Cck 192 0.48 30.64 163.46 99.52
171 INT5025 Positive_regulation of Gene_expression of Cck 63 0.70 10.96 47.11 99.52
172 INT15673 Positive_regulation of Transcription of Cck 4 0.69 1.62 3.84 99.52
173 INT79805 Phosphorylation of PRKCA 57 0.81 23.33 20.41 99.52
174 INT416 Regulation of LH 253 0.62 31.48 125.55 99.50
175 INT2106 Regulation of Localization of LH 279 0.62 22.37 122.77 99.50
176 INT2056 Negative_regulation of Gnrh1 175 0.59 33.43 63.32 99.44
177 INT21185 Binding of Ptprg 213 0.47 13.49 157.75 99.44
178 INT443 Localization of POMC 1020 0.81 284.52 443.17 99.44
179 INT20881 Negative_regulation of OPRK1 20 0.43 3.73 13.37 99.44
180 INT82033 Gene_expression of Isyna1 2 0.12 0.95 1.33 99.44
181 INT150411 Positive_regulation of Cd164l2 1 0.02 0.26 0.7 99.44
182 INT18616 Positive_regulation of Positive_regulation of Adarb1 18 0.33 2.04 13.18 99.44
183 INT111258 Regulation of Rgs9 11 0.54 1.81 8.9 99.42
184 INT920 Localization of PLOD1 223 0.81 42.25 78.7 99.42
185 INT126289 Regulation of Rgs17 3 0.41 0.89 5.47 99.42
186 INT126299 Regulation of Rgs20 3 0.41 0.89 2.5 99.42
187 INT126276 Regulation of Rgs14 1 0.39 0.71 1.63 99.42
188 INT126285 Regulation of Rgs4 4 0.62 1.05 2.36 99.42
189 INT5540 Positive_regulation of Oprm1 344 0.70 76.77 319.71 99.40
190 INT8989 Binding of Npr1 25 0.36 5.52 14.58 99.40
191 INT37296 Binding of Esr1 117 0.43 62.51 27.33 99.38
192 INT77398 Negative_regulation of ARRB1 1 0.47 0 1.31 99.38
193 INT287 Localization of Cck 518 0.81 86.84 364.04 99.36
194 INT2862 Positive_regulation of Localization of Cck 108 0.70 20.75 94.25 99.36
195 INT248 Positive_regulation of Localization of GH1 137 0.69 49.25 32.92 99.36
196 INT12780 Binding of Fads1 7 0.08 0.07 5.34 99.36
197 INT16303 Negative_regulation of Localization of GH1 89 0.59 37.31 22.15 99.36
198 INT77408 Binding of ARRB1 11 0.36 0.31 6.51 99.36
199 INT116081 Negative_regulation of Binding of ARRB1 1 0.41 0 0.72 99.36
200 INT6438 Positive_regulation of RAN 6 0.42 2.09 1.59 99.36
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