P:Demyelination

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pChart

Pain Term
Category Process
Synonyms None
Pain Specific No
Documents 1042
Hot Single Events 200
Hot Interactions 76

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Demyelination. They are ordered first by their pain relevance and then by number of times they were reported for Demyelination. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT326575 Nrg1 Positive_regulation of Gene_expression of JUN 1 0.38 0.86 0.2 99.64
2 INT334632 Binding of Kcna2 and Eae1 1 0.17 0.87 0.35 99.60
3 INT206764 Binding of AQP4 and Nqo1 8 0.05 13.45 2.84 99.46
4 INT231392 Enpp2 Positive_regulation of Gene_expression of Lpar1 2 0.38 2.19 0.93 99.36
5 INT161224 Ccl2 Positive_regulation of Ccr2 1 0.52 2.09 1.88 99.02
6 INT161225 Ccl2 Positive_regulation of Ccl2 Positive_regulation of Ccr2 1 0.57 2.09 1.88 99.02
7 INT344974 Lpar1 Regulation of Gene_expression of Mag 1 0.25 0.98 0.76 98.84
8 INT334631 Igf1r Positive_regulation of Phosphorylation of Akt1 1 0.19 0.5 0.18 98.64
9 INT222248 Binding of Cxcr3 and Cxcl10 1 0.35 0.48 0.09 98.60
10 INT93701 Binding of TNF and TNFAIP2 1 0.02 0.97 0.11 98.08
11 INT128944 Binding of Mbp and Mog 1 0.08 0.8 0.43 96.92
12 INT139429 LPA Positive_regulation of Negative_regulation of MBP 1 0.00 0.78 0.56 96.80
13 INT128945 Binding of MBP and Mog 1 0.01 1.59 0.86 96.72
14 INT282129 Il10 Positive_regulation of Icam1 1 0.56 3.12 0.82 96.72
15 INT181436 Binding of Ccl2 and Eae1 1 0.05 5.14 1.27 96.48
16 INT328981 Binding of Mup1 and Cts 1 0.14 1.05 0.88 96.48
17 INT328982 Binding of Igfals and Cts 1 0.05 0.92 0.8 96.48
18 INT328976 Binding of Cst7 and Cts 1 0.08 0.92 0.79 96.48
19 INT328979 Binding of Muted and Cts 1 0.03 0.9 0.78 96.48
20 INT240537 Binding of Il12a and Ebi3 1 0.08 1.23 0.49 95.72
21 INT339072 Eae1 Positive_regulation of Gene_expression of Nos2 1 0.02 3.76 0.59 94.84
22 INT259023 CADPS Positive_regulation of Binding of SH2B2 1 0.06 2.05 0.14 94.24
23 INT85879 Il12a Positive_regulation of Gene_expression of Ifng 1 0.20 0.89 0.92 93.52
24 INT328978 Binding of Igfals and Muted 1 0.02 0.85 0.73 93.28
25 INT328980 Binding of Cst7 and Igfals 1 0.06 0.85 0.73 93.28
26 INT328975 Binding of Igfals and Mup1 1 0.11 0.85 0.73 93.28
27 INT328983 Binding of Cst7 and Muted 1 0.04 0.84 0.73 93.28
28 INT328977 Binding of Cst7 and Mup1 1 0.18 0.84 0.73 93.28
29 INT328974 Binding of Muted and Mup1 1 0.06 0.83 0.71 93.28
30 INT282128 Gene_expression of Il10 Positive_regulation of Positive_regulation of Icam1 1 0.37 1.12 0.28 93.04
31 INT339070 Mog Positive_regulation of Eae1 1 0.01 3.81 0.61 92.96
32 INT241911 Binding of Cat and Ros1 1 0.03 0.85 0.27 90.48
33 INT102162 Binding of TNF and Adam17 1 0.14 0.88 0.78 90.32
34 INT102159 Binding of Adam17 and Mmp2 1 0.18 0.87 0.77 90.32
35 INT139683 Binding of Cldn11 and 2410016O06Rik 1 0.02 1.06 0.4 90.32
36 INT222251 Negative_regulation of Binding of Cxcl10 and Tcf21 1 0.23 0.34 0.32 90.28
37 INT222247 Binding of Cxcl10 and Tcf21 1 0.20 0.34 0.32 90.28
38 INT10363 Binding of Tmem33 and RT1-Db1 1 0.00 0.92 0.21 90.08
39 INT139684 Binding of Cd4 and 2410016O06Rik 1 0.02 1.05 0.4 89.72
40 INT181451 Lck Regulation of Mbp 1 0.08 1.43 0.34 89.64
41 INT102160 Binding of Mmp2 and Mmp9 3 0.28 2.87 1.75 89.60
42 INT102163 Binding of TNF and Mmp9 1 0.12 0.88 0.78 89.60
43 INT231390 Pla2g4a Regulation of Pla2g2a 1 0.08 0.92 0.77 89.44
44 INT344973 Negative_regulation of Mmp23 Regulation of Negative_regulation of Mag 1 0.01 1.14 0.99 89.36
45 INT231388 Pla2g4a Regulation of Pla2g6 1 0.08 0.92 0.77 89.20
46 INT95148 CEL Regulation of IL1B 1 0.24 0.88 0.7 89.20
47 INT102161 Binding of TNF and Mmp2 1 0.10 0.88 0.78 88.72
48 INT181450 Binding of Ccr5 and Ccl3 4 0.18 2.19 1.03 88.40
49 INT350717 MIR219-1 Negative_regulation of Zfp238 1 0.01 0.4 0.16 88.40
50 INT270044 Il10 Positive_regulation of Positive_regulation of Hmox1 1 0.20 1.59 0.53 88.24
51 INT270046 Ido1 Positive_regulation of Positive_regulation of Hmox1 1 0.15 0.8 0.27 88.24
52 INT222253 Binding of Cxcl10 and Fig4 1 0.09 0.66 0.65 88.08
53 INT350719 MIR219-1 Negative_regulation of Foxj3 1 0.01 0.4 0.15 87.44
54 INT167795 Negative_regulation of LPA Negative_regulation of Mag 1 0.01 0.84 0.64 87.08
55 INT167794 LPA Negative_regulation of Mag 1 0.01 0.77 0.63 87.08
56 INT334634 Binding of Igf1 and Igf1r 1 0.14 0.45 0.15 86.88
57 INT350723 MIR219-1 Negative_regulation of Sox6 1 0.01 0.4 0.15 86.88
58 INT326574 Binding of Akt1 and Hsp90ab1 1 0.13 0.17 0.08 86.76
59 INT350713 MIR219-1 Negative_regulation of Pdgfra 1 0.00 0.4 0.15 86.40
60 INT183387 Il6 Positive_regulation of Gene_expression of Il10 2 0.19 1.8 0.63 86.36
61 INT321957 Binding of Sar1a and Ceacam1 1 0.01 0.96 0.16 85.76
62 INT83626 Ifng Positive_regulation of Gene_expression of Cd59 1 0.33 2.19 1.41 85.56
63 INT351365 LPA Positive_regulation of Localization of Il6 1 0.00 1.79 0.54 85.20
64 INT83628 TNF Positive_regulation of Gene_expression of Cd59 1 0.06 1.09 0.7 84.28
65 INT97188 Gh Positive_regulation of Localization of Igf1 1 0.02 0.54 0.25 84.00
66 INT36999 Binding of HLA-DRB2 and TNFRSF25 1 0.05 3.46 0.91 83.44
67 INT83625 Tnf Positive_regulation of Gene_expression of Cd59 1 0.15 1.08 0.69 83.16
68 INT250247 FCGR3A Negative_regulation of AQP4 1 0.01 0.87 0.62 82.56
69 INT355881 Il17a Regulation of Gene_expression of Hand1 1 0.18 1.51 0.54 81.52
70 INT355878 Il17a Regulation of Eae1 1 0.06 1.52 0.54 81.52
71 INT355880 Il17a Regulation of Abi3 1 0.00 1.52 0.54 81.52
72 INT222252 Positive_regulation of Binding of Ccr2 and Fig4 1 0.16 0.67 0.55 80.44
73 INT222249 Positive_regulation of Binding of Ccr2 and Tcf21 1 0.39 0.67 0.55 80.44
74 INT222245 Binding of Ccr2 and Fig4 1 0.12 0.67 0.55 80.44
75 INT222246 Binding of Ccr2 and Tcf21 1 0.29 0.67 0.55 80.44
76 INT122567 Mog Positive_regulation of Eae1 8 0.31 10.18 4.26 80.24
77 INT140172 Binding of Nqo1 and IgG 5 0.17 6.68 1.2 79.36
78 INT235975 Binding of AQP4 and IgG 2 0.04 4.11 0.53 79.36
79 INT327789 Binding of IgG and Alms1 1 0.01 1.1 0.17 79.36
80 INT327790 Binding of Nqo1 and Alms1 1 0.00 1.1 0.17 79.36
81 INT327791 Binding of AQP4 and Alms1 1 0.03 1.1 0.17 79.36
82 INT222243 Negative_regulation of Binding of Trpv1 and Ccr5 1 0.21 0.57 0.86 78.96
83 INT222244 Binding of Trpv1 and Ccr5 1 0.19 0.57 0.86 78.96
84 INT222178 SERPINB1 Regulation of ELANE 1 0.00 1.04 0.23 78.80
85 INT222184 SERPINB1 Regulation of PRTN3 1 0.00 1.04 0.23 78.80
86 INT281130 Ccl2 Regulation of Gene_expression of Ccr2 1 0.04 1.09 0.64 77.40
87 INT281134 Ccl2 Positive_regulation of Gene_expression of Ccr2 1 0.08 1.09 0.64 77.40
88 INT281122 Ccl2 Regulation of Ccr2 1 0.04 1.09 0.63 77.40
89 INT308484 Car2 Positive_regulation of Pla2g4a 1 0.03 1.23 0.65 75.48
90 INT292873 Binding of Fas and Fasl 5 0.26 15.74 0.49 75.28
91 INT82024 Binding of Ngfr and Ngf 2 0.33 1.48 1.05 75.12
92 INT289333 Binding of Ngfr and Rtn4r 1 0.03 2.35 0.72 74.40
93 INT289332 Binding of Ngfr and Lingo1 1 0.04 2.36 0.72 74.40
94 INT308704 Binding of DDX41 and M1 1 0.02 2.09 0.1 74.20
95 INT326573 Zic2 Positive_regulation of Localization of Hsf1 1 0.01 0.95 0.07 73.16
96 INT92430 LOC681261 Positive_regulation of Ean2 1 0.01 1.52 1.41 73.04
97 INT196591 Binding of Lpar1 and Pax3 1 0.05 1.1 0.92 68.40
98 INT270043 Binding of Ldlr and Hdl1 1 0.01 2.3 0.43 66.60
99 INT19476 Binding of IL1A and Il6 1 0.00 2.19 0.36 66.28
100 INT19477 Binding of IL1A and Csf2 1 0.00 2.19 0.36 66.28
101 INT289357 Ngfr Positive_regulation of Akt1 1 0.03 3.1 0.66 65.64
102 INT237777 Il23a Regulation of Localization of Il12a 1 0.19 0.93 0.19 64.48
103 INT102201 Tnf Regulation of Il1b 3 0.39 2.57 0.82 64.08
104 INT297344 Apoe Regulation of Binding of Alms1 1 0.08 1.1 0.61 64.00
105 INT297340 Apoe Regulation of Binding of Smo 1 0.10 1.1 0.6 64.00
106 INT250253 Binding of AQP4 and SLC1A2 1 0.30 2.95 1.09 62.44
107 INT287746 Anxa1 Positive_regulation of Gene_expression of Lpar1 1 0.07 1.72 2.46 60.32
108 INT318028 Binding of IRF6 and Tlr4 1 0.00 0.61 0.06 59.48
109 INT182044 Binding of Proc and IgG 1 0.00 2.38 0.74 59.48
110 INT116862 Apoe Positive_regulation of Il10 1 0.30 0.69 0.5 57.48
111 INT116863 Apoe Negative_regulation of Hand1 1 0.37 0.69 0.5 57.48
112 INT88141 Hrh1 Positive_regulation of 1700061J05Rik 1 0.01 1.08 0.66 55.76
113 INT88142 Pt Positive_regulation of 1700061J05Rik 1 0.04 1.08 0.66 55.76
114 INT166134 Binding of Cxcl12 and Cxcr4 3 0.49 5.69 3.17 55.36
115 INT308701 Binding of AQP4 and DDX41 1 0.15 3.53 0.32 55.16
116 INT231391 Binding of Lpar1 and Rbm39 1 0.00 1.04 1.04 55.04
117 INT329085 Csf2 Positive_regulation of Apoe 1 0.00 1.23 0.42 54.56
118 INT308750 Binding of BCL2L1 and MIR184 1 0.13 0.11 0.03 54.40
119 INT339071 Binding of Mog and Eae1 1 0.00 1.65 0.06 51.68
120 INT308483 Paf Positive_regulation of Gene_expression of Ptafr 1 0.12 1.14 0.78 50.80
121 INT308485 Paf Positive_regulation of Ptafr 1 0.12 1.13 0.77 50.80
122 INT254492 Dtx1 Regulation of Cldn11 1 0.03 0 0.09 49.64
123 INT334633 Binding of Cntnap1 and Nav1 1 0.10 1.36 1.48 45.84
124 INT308707 Binding of AQP4 and IGHG3 1 0.01 0.88 0 42.84
125 INT307781 Apoa1 Positive_regulation of LCAT 1 0.76 1.19 0.45 40.96
126 INT307780 Apoa1 Positive_regulation of Soat1 1 0.04 1.14 0.42 40.48
127 INT181448 Eae1 Positive_regulation of Gene_expression of Ccr2 1 0.04 4.98 0.42 40.40
128 INT297342 Binding of Gnb5 and Smo 1 0.02 1.67 0.34 39.52
129 INT281154 ITIH4 Positive_regulation of Cxcr4 1 0.09 0.71 0.37 38.92
130 INT281128 Cd4 Positive_regulation of Cxcr4 1 0.25 0.71 0.37 38.92
131 INT315204 Binding of Epo and Nefh 1 0.26 1.01 0.09 38.32
132 INT355018 Binding of FAS and Faslg 1 0.12 1.34 0.37 38.16
133 INT315205 Binding of Nefh and Cnp 1 0.24 1 0.09 37.76
134 INT241912 Cat Positive_regulation of Ros1 1 0.03 0.76 0.44 36.16
135 INT298873 RAB7A Regulation of Protein_catabolism of NTRK1 1 0.12 0.25 0.03 35.92
136 INT169648 IGHG3 Regulation of AQP4 3 0.02 4.63 0.55 35.84
137 INT308708 DDX41 Regulation of AQP4 1 0.10 2.79 0.26 35.84
138 INT241914 SOD1 Positive_regulation of Ros1 1 0.00 0.76 0.44 35.64
139 INT287740 Lpar3 Regulation of Gene_expression of Lpar1 1 0.60 0.53 0.39 31.60
140 INT181453 Gene_expression of Ccl2 Positive_regulation of Gene_expression of Il12rb1 1 0.06 1.87 0.34 30.96
141 INT334869 Nrg1 Positive_regulation of Phosphorylation of C3 1 0.08 0 0.03 30.68
142 INT324694 Tlr4 Positive_regulation of Gene_expression of Pnoc 1 0.05 0.56 0.24 30.08
143 INT298872 RAB7A Regulation of Protein_catabolism of GFM1 1 0.47 0.22 0.03 29.28
144 INT349031 Epo Positive_regulation of Akt1 1 0.36 0.23 0.09 28.72
145 INT334863 Positive_regulation of Binding of Mpz and Nfatc1 1 0.08 0 0.11 27.32
146 INT334866 Binding of Mpz and Nfatc1 1 0.06 0 0.11 27.32
147 INT334868 Binding of C4b and Nfatc1 1 0.01 0 0.06 27.32
148 INT334864 Positive_regulation of Binding of Nfatc1 and Sox10 1 0.04 0 0.03 27.32
149 INT334873 Binding of Nfatc1 and Sox10 1 0.02 0 0.03 27.32
150 INT334870 Binding of C4b and Mpz 1 0.10 0 0.11 27.12
151 INT334861 Positive_regulation of Binding of C4b and Mpz 1 0.13 0 0.11 27.12
152 INT334867 Binding of C4b and Sox10 1 0.04 0 0.03 27.12
153 INT334872 Positive_regulation of Binding of C4b and Sox10 1 0.04 0 0.03 27.12
154 INT334871 Binding of Mpz and Sox10 1 0.13 0 0.11 27.00
155 INT334862 Positive_regulation of Binding of Mpz and Sox10 1 0.17 0 0.11 27.00
156 INT297332 Apoe Negative_regulation of Gene_expression of Mpz 1 0.02 1.09 0.87 24.44
157 INT297336 1700061J05Rik Negative_regulation of Gene_expression of Mpz 1 0.00 1.08 0.86 23.04
158 INT181454 Eae7 Regulation of Positive_regulation of Eae1 1 0.06 0.9 0.26 21.68
159 INT345190 Lpar1 Regulation of Localization of Il6 1 0.05 1.19 0.04 21.44
160 INT281133 Binding of Ccl2 and Cxcr4 1 0.06 0.63 0.24 19.96
161 INT328004 Binding of CYBB and Gnb5 1 0.00 1.13 0.15 19.92
162 INT307665 Binding of Mpz and Pmp22 1 0.34 0.39 0.08 18.04
163 INT307666 Binding of Pmp22 and Gjb1 1 0.31 0.38 0.08 18.04
164 INT307663 Binding of Pmp22 and Egr2 1 0.33 0.39 0.08 18.04
165 INT307664 Binding of Pmp22 and LOC689781 1 0.03 0.39 0.08 18.04
166 INT308703 Positive_regulation of Binding of AQP4 and M1 1 0.08 0.61 0 16.08
167 INT308706 Binding of AQP4 and M1 1 0.06 0.86 0 15.56
168 INT281733 LTK Regulation of IgG 1 0.00 1.37 0.03 11.92
169 INT352417 Ccl2 Positive_regulation of Ccr5 1 0.06 0.26 0.14 9.68
170 INT352416 Ccl2 Positive_regulation of Ccr2 1 0.23 0.26 0.14 8.96
171 INT308748 TPPP Regulation of MIR1-1 1 0.04 0.13 0.03 8.52
172 INT77646 Binding of Ngf and Ntrk1 23 0.40 7.85 9.26 5.00
173 INT149117 Binding of CD80 and CTLA4 31 0.52 12.7 7.73 5.00
174 INT106559 Binding of Bdnf and Ntrk2 23 0.43 11.09 7.33 5.00
175 INT155484 Binding of CD86 and CTLA4 15 0.52 8.85 6.09 5.00
176 INT88279 Ngf Positive_regulation of Ntrk1 5 0.76 3.06 5.23 5.00
177 INT351352 Binding of Trpv1 and Lpar1 1 0.21 5.86 4.62 5.00
178 INT73539 Binding of Ngf and Ngfr 5 0.45 3.99 4 5.00
179 INT181455 Binding of Ccr5 and Ccl5 11 0.39 12.13 3.66 5.00
180 INT194647 Binding of CD28 and CD80 15 0.40 4.9 3.22 5.00
181 INT211694 Binding of Cntnap1 and Nav1 1 0.04 0 3.14 5.00
182 INT186126 Binding of CD28 and CTLA4 9 0.52 4.13 3.12 5.00
183 INT351349 Prkcg Positive_regulation of Binding of Lpar1 1 0.15 2 2.82 5.00
184 INT175329 Binding of ICAM1 and ITGAL 14 0.18 10.06 2.81 5.00
185 INT122163 Binding of TNF and TNFRSF1B 6 0.44 6.06 2.41 5.00
186 INT275398 Binding of ITIH4 and Htatsf1 1 0.02 5.05 2.24 5.00
187 INT279361 Binding of TNF and KLF1 4 0.00 3.72 2.19 5.00
188 INT148704 Binding of TNF and TNFRSF1A 5 0.44 3.3 2.09 5.00
189 INT145940 Binding of Gad1 and Abat 2 0.14 1.44 1.78 5.00
190 INT66504 Binding of Agt and Agtr1a 8 0.39 3.78 1.78 5.00
191 INT306745 Binding of Il12a and IL23A 1 0.10 3.25 1.56 5.00
192 INT351366 LPA Positive_regulation of Rab38 1 0.00 0.95 1.53 5.00
193 INT222185 Binding of Ccr1 and Ccl3 4 0.23 2.7 1.47 5.00
194 INT351246 Binding of OPN1LW and NNT 1 0.03 0.53 1.45 5.00
195 INT222213 TFAM Positive_regulation of Gene_expression of Ccr1 1 0.02 3.96 1.4 5.00
196 INT222182 Binding of ESR1 and HLA-DRB2 1 0.00 3.1 1.35 5.00
197 INT351245 Binding of TNC and OPN1LW 1 0.03 0.89 1.31 5.00
198 INT186393 Binding of TNF and Tnfrsf1a 9 0.37 8.55 1.29 5.00
199 INT236835 Binding of CISH and CSF2 1 0.06 1.43 1.25 5.00
200 INT287749 Dmbx1 Positive_regulation of Gene_expression of Lpar1 1 0.41 0.82 1.16 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Demyelination. They are ordered first by their pain relevance and then by number of times they were reported in Demyelination. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT154094 Negative_regulation of Eae1 25 0.18 30.42 7.89 100.00
2 INT165490 Regulation of Lpar1 8 0.45 15.31 5.05 100.00
3 INT344969 Positive_regulation of Regulation of Mag 1 0.33 1.15 0.7 100.00
4 INT344968 Regulation of Regulation of Lpar1 1 0.39 1.15 0.7 100.00
5 INT344970 Regulation of Regulation of Mag 1 0.32 1.15 0.7 100.00
6 INT228872 Negative_regulation of Gene_expression of Dmbx1 3 0.41 3.75 1.46 100.00
7 INT295239 Negative_regulation of Anxa1 2 0.02 1.6 0.81 100.00
8 INT344967 Positive_regulation of Negative_regulation of Mag 1 0.33 1.15 0.69 100.00
9 INT183372 Regulation of Galc 1 0.44 1.86 0.56 100.00
10 INT161221 Positive_regulation of Positive_regulation of Ccr2 3 0.50 4.55 3.98 100.00
11 INT287730 Positive_regulation of Gene_expression of Tpnr1 1 0.01 1.43 1.08 100.00
12 INT111263 Gene_expression of Gnb5 8 0.75 8.51 3 100.00
13 INT163592 Localization of CISH 5 0.54 5.9 1.26 100.00
14 INT329079 Negative_regulation of Positive_regulation of Apod 1 0.03 1.54 0.54 100.00
15 INT270030 Negative_regulation of Positive_regulation of Hmox1 3 0.30 2.49 0.47 100.00
16 INT86521 Gene_expression of Lpar1 167 0.78 154.61 80.35 99.96
17 INT11807 Gene_expression of Il2 266 0.78 112 64.97 99.96
18 INT6830 Positive_regulation of Notch1 20 0.55 7.91 1.57 99.92
19 INT128946 Regulation of PNPLA6 1 0.27 2.14 0.36 99.92
20 INT183375 Binding of Nppa 14 0.38 8.95 0.51 99.92
21 INT81629 Positive_regulation of Fas 58 0.70 59.63 12.94 99.92
22 INT80228 Positive_regulation of Gene_expression of Hmox1 68 0.70 62.88 14.01 99.92
23 INT153913 Positive_regulation of Lpar1 31 0.70 33.5 16.14 99.90
24 INT149832 Gene_expression of Tpnr1 3 0.02 4.78 3.75 99.90
25 INT39005 Negative_regulation of FBN1 7 0.42 4.97 2.6 99.90
26 INT71350 Positive_regulation of Tpnr1 3 0.01 3.92 4.08 99.90
27 INT287731 Regulation of Gene_expression of Tpnr1 1 0.00 1.47 1.25 99.88
28 INT96915 Phosphorylation of Mapk8 73 0.81 40.69 11.44 99.88
29 INT22900 Positive_regulation of Cd4 126 0.67 82.77 16.43 99.88
30 INT166114 Gene_expression of Dmbx1 36 0.74 29.64 12.28 99.84
31 INT98789 Negative_regulation of Gene_expression of App 54 0.58 40.27 11.15 99.82
32 INT5207 Negative_regulation of Alms1 70 0.41 41.56 13.68 99.80
33 INT102187 Gene_expression of SH2B2 23 0.59 26.54 4.39 99.80
34 INT190396 Positive_regulation of Gene_expression of Scn8a 2 0.45 0.77 0.86 99.78
35 INT88046 Gene_expression of Ccr2 38 0.76 33.76 28.07 99.76
36 INT151434 Positive_regulation of Ccr2 26 0.68 18.34 16.34 99.76
37 INT222233 Gene_expression of Cxcl12 42 0.69 32.64 10.13 99.76
38 INT161222 Positive_regulation of Ccr2 13 0.55 13.77 8.89 99.76
39 INT88047 Positive_regulation of Gene_expression of Ccr2 15 0.60 10.5 8.63 99.76
40 INT25222 Positive_regulation of Gene_expression of Ifng 32 0.50 24.18 19.58 99.76
41 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54 99.76
42 INT68975 Gene_expression of Mmp9 111 0.78 79.57 38.55 99.76
43 INT125896 Negative_regulation of Gene_expression of Mmp9 15 0.43 13.73 4.18 99.76
44 INT80305 Gene_expression of IGKV2-30 6 0.04 3.68 1.01 99.76
45 INT163396 Negative_regulation of Gene_expression of IGKV2-30 1 0.00 1.24 0.8 99.76
46 INT183371 Positive_regulation of Galc 11 0.67 7.27 3.49 99.72
47 INT80223 Positive_regulation of Hmox1 128 0.68 77.71 17.64 99.70
48 INT204825 Negative_regulation of Plp1 3 0.33 2.96 0.87 99.68
49 INT65500 Gene_expression of App 605 0.78 429.94 98.31 99.66
50 INT96741 Gene_expression of Cxcr4 62 0.78 32.3 22.14 99.64
51 INT231379 Negative_regulation of Negative_regulation of Pmp22 1 0.26 1.72 1.09 99.64
52 INT72651 Gene_expression of TH1L 114 0.75 80.15 35.15 99.64
53 INT156348 Regulation of Mup1 10 0.52 6.79 4.6 99.64
54 INT231261 Regulation of Nrg1 3 0.31 1.32 0.15 99.64
55 INT14634 Negative_regulation of Sqle 3 0.52 0.89 0.39 99.62
56 INT186623 Negative_regulation of Mag 13 0.42 12.22 6.48 99.60
57 INT162624 Regulation of Mag 9 0.44 8.28 4.28 99.60
58 INT93620 Positive_regulation of Gene_expression of Fasl 51 0.66 59.45 12.04 99.60
59 INT93626 Gene_expression of Fasl 118 0.75 115.24 25.11 99.60
60 INT14637 Negative_regulation of MBP 19 0.43 7.06 7.18 99.60
61 INT344966 Negative_regulation of Regulation of Mag 1 0.42 1.62 0.93 99.60
62 INT344971 Regulation of Negative_regulation of Mag 1 0.19 1.08 0.66 99.60
63 INT46273 Gene_expression of PRNP 103 0.78 110.34 9.25 99.60
64 INT82878 Gene_expression of Ccl2 201 0.78 164.95 101.35 99.58
65 INT84170 Positive_regulation of Gene_expression of Ccl2 58 0.69 48.79 32.43 99.58
66 INT82883 Positive_regulation of Ccl2 105 0.69 84.96 42.27 99.58
67 INT183370 Negative_regulation of Galc 1 0.42 6.11 2.59 99.56
68 INT39884 Negative_regulation of Mbp 23 0.56 11.93 3.21 99.54
69 INT231373 Negative_regulation of Pmp22 1 0.26 2.98 1.75 99.54
70 INT10359 Gene_expression of Ifng 159 0.78 79.6 72.14 99.52
71 INT119378 Positive_regulation of Gene_expression of Ppp2r2c 1 0.03 0.76 0.87 99.52
72 INT1990 Positive_regulation of Ean5 35 0.41 38.05 28.8 99.50
73 INT205198 Positive_regulation of Lpar1 2 0.35 7.35 6.37 99.48
74 INT55924 Negative_regulation of IGKV2-30 3 0.07 2.26 1.8 99.48
75 INT157959 Binding of AQP4 32 0.48 43.44 7.44 99.46
76 INT149831 Negative_regulation of Dmbx1 8 0.52 13.01 4.36 99.46
77 INT5430 Gene_expression of Scn8a 37 0.75 4.58 14.82 99.46
78 INT124297 Gene_expression of Sod2 112 0.77 65.65 7.64 99.44
79 INT310662 Negative_regulation of Ears2 1 0.19 2.08 0.75 99.44
80 INT270033 Regulation of Gene_expression of Sod2 5 0.45 2.34 0.63 99.44
81 INT78226 Gene_expression of Mbp 43 0.75 22.14 7.79 99.42
82 INT139169 Gene_expression of Pmp22 10 0.68 8.37 2.5 99.42
83 INT536 Binding of MBP 17 0.48 6.52 3.56 99.42
84 INT192980 Negative_regulation of NeuN 14 0.36 5.24 2.32 99.40
85 INT118343 Positive_regulation of Eae1 121 0.39 136.06 34.87 99.38
86 INT64636 Positive_regulation of Gene_expression of Nos2 242 0.70 147.52 79.53 99.38
87 INT9660 Regulation of TNF 363 0.62 312.94 139.99 99.36
88 INT355015 Protein_catabolism of Mbp 1 0.21 2.47 0.61 99.34
89 INT136304 Negative_regulation of Aqp4 54 0.59 48.42 7.4 99.32
90 INT6861 Negative_regulation of Gfap 32 0.58 13.71 7.22 99.32
91 INT69878 Positive_regulation of Gene_expression of Gtf3a 48 0.29 36.78 13.57 99.32
92 INT899 Gene_expression of F13A1 122 0.70 78.02 16.26 99.32
93 INT119379 Gene_expression of Ppp2r2c 1 0.04 0.76 0.87 99.32
94 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 99.28
95 INT287735 Positive_regulation of Gene_expression of Dmbx1 10 0.45 7.6 1.72 99.28
96 INT14556 Positive_regulation of Igf1 105 0.69 52.21 24.04 99.28
97 INT222241 Binding of Ccr2 5 0.42 4.09 3.71 99.28
98 INT286068 Positive_regulation of Positive_regulation of Igf1 2 0.40 1.03 0.16 99.28
99 INT100661 Regulation of Cst7 18 0.53 5.93 7.8 99.28
100 INT264243 Binding of Cpz 4 0.32 1.26 0.29 99.28
101 INT239599 Binding of Stt3b 1 0.01 3.55 0.85 99.26
102 INT250282 Negative_regulation of AQP4 32 0.54 32.96 9.07 99.24
103 INT60695 Positive_regulation of Gene_expression of Il10 154 0.70 120.28 43.07 99.24
104 INT250351 Positive_regulation of Gene_expression of Best1 5 0.27 3.14 0.65 99.24
105 INT73982 Gene_expression of Hmox1 141 0.78 119.43 32.17 99.20
106 INT48953 Positive_regulation of Nos2 486 0.70 239.85 131.87 99.16
107 INT10166 Localization of Tnf 237 0.81 153.95 88.64 99.16
108 INT14149 Binding of C6orf25 11 0.48 9.04 1.71 99.16
109 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08 99.14
110 INT166115 Positive_regulation of Gene_expression of Lpar1 42 0.61 31 20.71 99.12
111 INT115384 Positive_regulation of Mmp9 121 0.68 94.74 43.02 99.12
112 INT19509 Localization of Ifng 55 0.78 28.25 18.67 99.12
113 INT134253 Gene_expression of KCNA2 2 0.65 1.04 2.35 99.12
114 INT70918 Positive_regulation of Localization of Ifng 5 0.45 2.79 2.33 99.12
115 INT334624 Positive_regulation of Gene_expression of Kcna2 1 0.49 0.86 0.35 99.12
116 INT215353 Gene_expression of Tcf21 16 0.59 9.71 9.49 99.08
117 INT170295 Positive_regulation of Ido1 40 0.67 28.89 7.61 99.08
118 INT125247 Negative_regulation of Mmp9 42 0.43 23.68 9.37 99.08
119 INT39060 Gene_expression of Mpz 45 0.77 21.55 4.3 99.08
120 INT14887 Gene_expression of Mbp 55 0.75 36.13 16.11 99.04
121 INT120550 Negative_regulation of Rock1 27 0.42 18.38 5.66 99.04
122 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 99.04
123 INT138696 Positive_regulation of Ccl2 57 0.67 59.57 19.58 99.02
124 INT154751 Positive_regulation of Positive_regulation of Ccl2 2 0.48 2.43 2.06 99.02
125 INT83622 Positive_regulation of Gene_expression of Cd59 4 0.49 3.77 2.35 99.00
126 INT204851 Transcription of Plp1 1 0.40 1.38 0.42 99.00
127 INT6660 Positive_regulation of Jun 148 0.69 67.58 29.73 98.98
128 INT74614 Positive_regulation of Apoa1 16 0.68 23.95 5.04 98.98
129 INT103262 Localization of Nav1 53 0.81 19.23 34.44 98.92
130 INT48593 Positive_regulation of NOS1 420 0.68 226.15 114.71 98.92
131 INT12250 Negative_regulation of Mtr 19 0.50 6.9 5.35 98.92
132 INT302990 Protein_catabolism of MBP 5 0.88 3.75 1.42 98.92
133 INT541 Positive_regulation of MBP 31 0.67 28.56 12.24 98.92
134 INT334621 Gene_expression of Kcna2 1 0.65 0.86 0.34 98.92
135 INT334623 Negative_regulation of Gene_expression of Kcna2 1 0.41 0.86 0.34 98.92
136 INT111051 Negative_regulation of Nav1 64 0.59 25.51 47.27 98.90
137 INT111049 Negative_regulation of Positive_regulation of Nav1 5 0.43 4.39 6.25 98.90
138 INT24605 Negative_regulation of Scly 6 0.34 3.98 1.71 98.90
139 INT55123 Binding of Ceacam1 4 0.30 4.86 2.44 98.88
140 INT115386 Gene_expression of Ppara 779 0.77 549.99 128.36 98.88
141 INT228088 Localization of Ceacam1 6 0.54 4.64 0.85 98.88
142 INT321946 Negative_regulation of Binding of Ceacam1 1 0.19 1.45 0.5 98.88
143 INT87395 Binding of Ccr5 5 0.29 2.5 2.6 98.88
144 INT222232 Binding of Cxcr3 1 0.29 0.52 0.35 98.88
145 INT137767 Gene_expression of Eae1 74 0.34 89.32 20.48 98.84
146 INT6321 Negative_regulation of Ceacam1 5 0.43 3.35 1.89 98.84
147 INT11318 Gene_expression of Gtf3a 274 0.52 183.82 60.89 98.84
148 INT68974 Localization of Mmp9 10 0.80 4.84 3.35 98.84
149 INT102158 Protein_catabolism of Mmp9 7 0.65 5.43 1.91 98.84
150 INT178338 Gene_expression of Tbx15 50 0.65 38.65 12.19 98.82
151 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 98.80
152 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1 98.80
153 INT22340 Gene_expression of Rent1 11 0.05 5.19 4.8 98.76
154 INT222231 Transcription of Cxcl12 4 0.55 2.25 0.91 98.76
155 INT103845 Gene_expression of Cxcr3 13 0.60 10.65 8.5 98.72
156 INT46460 Gene_expression of NAV1 288 0.78 135.51 305.75 98.72
157 INT131413 Positive_regulation of Gene_expression of NAV1 35 0.70 17.5 36.83 98.72
158 INT531 Gene_expression of GH1 376 0.75 193.45 46.24 98.72
159 INT250517 Phosphorylation of Igf1r 5 0.79 1.21 0.21 98.64
160 INT185482 Binding of Cxcl10 5 0.30 3.76 3.13 98.60
161 INT153496 Negative_regulation of Pmp22 2 0.42 3.34 0.26 98.58
162 INT4282 Regulation of Msr1 11 0.45 2.51 5.75 98.56
163 INT146504 Regulation of Ccr2 5 0.39 3.58 2.21 98.56
164 INT37239 Positive_regulation of Ssta2 1 0.03 1.03 0.95 98.56
165 INT103847 Positive_regulation of Ccr5 11 0.55 6.04 5.79 98.52
166 INT82887 Positive_regulation of Ccl5 10 0.40 3.4 4.91 98.52
167 INT8959 Binding of Gnb5 17 0.40 31.38 5.1 98.52
168 INT50212 Gene_expression of Ifx 33 0.75 32.17 7.26 98.52
169 INT103843 Positive_regulation of Gene_expression of Ccr5 5 0.42 2.31 3.89 98.52
170 INT115616 Positive_regulation of Binding of Ccl5 3 0.25 0.59 2.04 98.52
171 INT140413 Gene_expression of AQP4 113 0.78 139.25 25.53 98.48
172 INT78023 Gene_expression of DDX41 13 0.65 23.55 3.84 98.48
173 INT83623 Gene_expression of Cd59 7 0.76 7.35 4.7 98.44
174 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 98.44
175 INT112207 Binding of Nav1 27 0.47 7.1 15.43 98.42
176 INT6585 Positive_regulation of Insrr 110 0.52 40.67 89.9 98.40
177 INT281144 Regulation of Gene_expression of Ccr2 2 0.44 2.38 3.29 98.40
178 INT218605 Negative_regulation of Kcna2 2 0.41 1.68 0.55 98.40
179 INT77310 Gene_expression of Aif1 89 0.78 50.49 33.68 98.36
180 INT84546 Positive_regulation of Ppara 481 0.70 334.21 83.45 98.34
181 INT103849 Positive_regulation of Gene_expression of Cxcr3 4 0.40 1.9 1.44 98.34
182 INT86062 Positive_regulation of Tnfrsf1a 51 0.69 40.69 26.2 98.32
183 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 98.32
184 INT53083 Gene_expression of Ptgs2 153 0.78 90.04 50.39 98.28
185 INT9650 Gene_expression of LPA 141 0.75 104.57 29 98.28
186 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 98.24
187 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 98.24
188 INT8631 Negative_regulation of Nfasc 12 0.42 3.33 5.71 98.24
189 INT64161 Positive_regulation of Prkca 213 0.70 85.06 129.91 98.22
190 INT252212 Negative_regulation of Gene_expression of Lgals3 5 0.43 4.82 0.88 98.22
191 INT354337 Positive_regulation of Negative_regulation of Mrs2 1 0.43 0.5 0.24 98.20
192 INT254486 Protein_catabolism of myelin 1 0.09 0.25 0.32 98.20
193 INT166881 Positive_regulation of Ccr1 31 0.69 18.14 7.9 98.20
194 INT112970 Regulation of Ccr1 8 0.29 7.77 1.93 98.20
195 INT278334 Negative_regulation of Hsp90ab1 3 0.30 4.34 0.68 98.16
196 INT56769 Gene_expression of Ntrk1 36 0.77 15.79 20.75 98.12
197 INT228870 Negative_regulation of Lpar1 17 0.51 20.97 8.77 98.12
198 INT103846 Regulation of Gene_expression of Cxcr3 2 0.35 2.09 1.52 98.08
199 INT174876 Regulation of Gene_expression of Fig4 18 0.39 7.83 2.44 98.08
200 INT132161 Gene_expression of MTX1 48 0.58 26.55 32.32 98.08
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