P:Desipramine

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pChart

Pain Term
Category Drug
Synonyms None
Pain Specific No
Documents 1194
Hot Single Events 200
Hot Interactions 33

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Desipramine. They are ordered first by their pain relevance and then by number of times they were reported for Desipramine. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT240193 RBX1 Positive_regulation of Gene_expression of BDNF 1 0.10 0 0.43 100.00
2 INT240192 RBX1 Negative_regulation of BDNF 1 0.08 0.13 0.52 99.80
3 INT113685 Binding of Cyp3a23/3a1 and Cyp2c11 1 0.35 0 0.65 99.06
4 INT77254 Binding of gr and Sp1 1 0.04 0.4 0.9 98.52
5 INT146897 Binding of Fst and OR13H1 1 0.01 0 1.05 98.34
6 INT77253 Binding of gr and Creb1 1 0.03 0.4 0.9 98.20
7 INT271193 Creb1 Regulation of Bdnf 1 0.15 0.28 0.81 96.84
8 INT271194 Binding of Bdnf and Gopc 1 0.03 0.49 0.6 96.72
9 INT271192 Binding of Gopc and Gtf3a 1 0.00 0.49 0.6 96.72
10 INT142826 UPF1 Positive_regulation of CREB1 1 0.11 0 0.46 96.60
11 INT321476 Binding of Slc6a3 and Slc6a2 1 0.01 0.41 1.14 95.44
12 INT321473 Binding of Slc6a3 and Ubqln1 1 0.00 0.41 1.13 95.44
13 INT33059 Dsp Negative_regulation of Localization of LH 1 0.18 0 0.8 95.12
14 INT321477 Binding of Ubqln1 and Flvcr2 1 0.00 0.81 2.26 95.04
15 INT321478 Binding of Slc6a2 and Flvcr2 1 0.00 0.41 1.14 95.04
16 INT62898 Binding of Oprl1 and Dsp 1 0.35 0 0.52 94.52
17 INT321474 Binding of Slc6a2 and Ubqln1 1 0.00 0.8 2.27 94.08
18 INT149470 Oxt Regulation of Gene_expression of Avp 1 0.46 1.2 1.92 94.00
19 INT149471 Avp Regulation of Gene_expression of Crh 1 0.45 0.6 0.96 94.00
20 INT149474 Avp Regulation of Gene_expression of Oxt 1 0.27 0.6 0.96 94.00
21 INT149469 Oxt Regulation of Gene_expression of Crh 1 0.45 1.2 1.91 93.80
22 INT272998 IL33 Negative_regulation of CYP2D6 1 0.04 0 0.25 93.48
23 INT164677 Ngf Positive_regulation of Gene_expression of Fos 1 0.52 0.08 0.89 93.44
24 INT35167 Adrb2 Positive_regulation of Trh 1 0.05 0 0.45 91.12
25 INT272997 Binding of CYP3A4 and IL33 1 0.03 0 0.25 90.84
26 INT92738 Binding of Ephb1 and Tcas1 1 0.00 0.43 2.67 89.40
27 INT223928 Cux1 Regulation of Gene_expression of Maoa 1 0.24 0.15 0.57 88.28
28 INT223924 Cux1 Regulation of Gene_expression of Serpina1 1 0.04 0.15 0.57 88.28
29 INT321475 Slc6a2 Positive_regulation of Ubqln1 1 0.00 0.38 1.19 86.64
30 INT123300 Mks1 Positive_regulation of Creb1 1 0.01 0.35 0.7 84.72
31 INT128276 ecs Regulation of Transcription of Slc17a7 1 0.01 0.29 0.65 83.56
32 INT34856 Hpd Negative_regulation of Dbh 1 0.00 0 0.39 82.16
33 INT123301 Car2 Positive_regulation of Creb1 1 0.21 0.28 0.61 81.12
34 INT29048 Oprd1 Regulation of Etf1 1 0.00 0 0.71 78.88
35 INT128275 Slc17a7 Positive_regulation of Transcription of Slc17a6 1 0.39 0.27 0.63 75.64
36 INT34855 Negative_regulation of Maoa Negative_regulation of Th 1 0.17 0 0.34 71.28
37 INT152298 Mmp9 Negative_regulation of Tsc22d1 1 0.13 0.16 0.66 67.64
38 INT152299 Mmp2 Negative_regulation of Tsc22d1 1 0.16 0.16 0.66 67.64
39 INT152296 Regulation of Mmp9 Negative_regulation of Tsc22d1 1 0.08 0.16 0.66 67.64
40 INT152297 Mmp2 Negative_regulation of Mmp9 1 0.39 0.16 0.65 66.16
41 INT55553 Avp Regulation of Serpina6 1 0.02 0 0.49 64.48
42 INT273939 Positive_regulation of Crem Negative_regulation of Transcription of Crh 1 0.18 0.99 0.39 64.32
43 INT273956 Binding of Crem and Negative_regulation of Transcription of Crh 1 0.18 0.99 0.39 64.32
44 INT280480 Binding of Bdnf and Ngfr 5 0.25 3.14 1.27 62.52
45 INT106559 Binding of Bdnf and Ntrk2 23 0.43 11.09 7.33 58.84
46 INT99292 Pth Positive_regulation of Jun 1 0.10 0.13 0.36 58.76
47 INT184919 Binding of da and Slc6a3 1 0.12 0.33 1.23 58.64
48 INT223925 Drd1a Positive_regulation of Gene_expression of Serpina1 1 0.01 0 0.51 58.36
49 INT321479 Ubqln1 Regulation of Cfp 1 0.00 0.37 0.67 58.08
50 INT273955 Creb1 Positive_regulation of Transcription of Crh 1 0.14 0.96 0.33 56.00
51 INT60208 Binding of Htr1a and Htr2c 2 0.52 0.25 1 54.40
52 INT47694 sps Regulation of Ntrk2 1 0.00 0.98 0.2 48.68
53 INT47695 sps Regulation of Bdnf 1 0.00 0.98 0.2 48.68
54 INT104050 Binding of Crh and Nts 1 0.40 0 0.6 46.04
55 INT60626 Crh Positive_regulation of Localization of Pomc 7 0.54 2.3 1.99 44.56
56 INT149473 Avp Positive_regulation of Localization of Pomc 4 0.48 2.64 0.56 44.56
57 INT60627 Crh Positive_regulation of Localization of Mc2r 2 0.11 0.44 0.53 44.08
58 INT149468 Avp Positive_regulation of Localization of Mc2r 1 0.07 0.26 0.21 44.08
59 INT273953 Crem Regulation of Transcription of Crh 1 0.26 0.99 0.27 41.76
60 INT273017 Binding of PDE1B and PDE11A 1 0.08 0.35 0.14 33.08
61 INT251623 Car2 Regulation of Gene_expression of Fig4 1 0.02 0.31 0.08 32.72
62 INT247266 Binding of Mecp2 and Fos 1 0.30 0.18 0.13 28.16
63 INT247267 Binding of Egr1 and Mecp2 1 0.12 0.18 0.13 28.16
64 INT21315 AGT Positive_regulation of Npy 1 0.03 0.15 0.5 25.00
65 INT315333 Binding of Cflar and Fadd 1 0.01 0.49 0.42 23.76
66 INT273019 Binding of PDE1A and MDD1 1 0.30 0.69 0.12 19.88
67 INT232427 ABAT Regulation of PRL 1 0.08 0.26 0.45 14.40
68 INT273936 Binding of Crem and Mrvi1 1 0.00 0.94 0.07 10.28
69 INT273937 Binding of Crem and Gabra1 1 0.30 0.94 0.07 10.28
70 INT273947 Binding of Gabra1 and Mrvi1 1 0.00 0.94 0.07 9.80
71 INT77646 Binding of Ngf and Ntrk1 23 0.40 7.85 9.26 5.00
72 INT131249 Binding of Bdnf and Ntrk2 11 0.41 4 6.25 5.00
73 INT172206 Binding of Slc6a3 and ADHD1 2 0.03 2.76 1.61 5.00
74 INT222335 Binding of Bdnf and Ngfr 3 0.05 2.66 1.48 5.00
75 INT242624 Binding of Ngf and Ntrk2 5 0.24 0.48 1.11 5.00
76 INT235709 Binding of NA and SSR1 1 0.07 0.72 1.08 5.00
77 INT232426 HRH2 Regulation of Localization of PRL 1 0.15 0.38 0.94 5.00
78 INT184916 Binding of da and Th 1 0.09 1.22 0.87 5.00
79 INT256045 Binding of BDNF and Ntrk1 3 0.34 0.65 0.83 5.00
80 INT184918 da Positive_regulation of Negative_regulation of Th 1 0.14 0.14 0.77 5.00
81 INT242626 Binding of Ngf and Ntrk3 3 0.15 0.27 0.77 5.00
82 INT235604 Binding of Htr1a and Htr3a 1 0.01 0 0.74 5.00
83 INT123229 OXTR Regulation of Localization of PRL 2 0.30 0 0.73 5.00
84 INT281857 Binding of Ltp and Cnnm1 1 0.00 0 0.71 5.00
85 INT165583 Binding of Bdnf and Ngf 3 0.33 0.81 0.69 5.00
86 INT242635 Binding of Bdnf and Ntrk3 3 0.25 0.98 0.64 5.00
87 INT330984 Negative_regulation of CYP2D6 Positive_regulation of Localization of CYP1A2 1 0.46 0 0.62 5.00
88 INT89902 SST Positive_regulation of Localization of PRL 2 0.40 0 0.61 5.00
89 INT223934 HSPG2 Negative_regulation of Gene_expression of Cux1 1 0.03 0 0.53 5.00
90 INT184878 Binding of Lmo1 and ADHD1 2 0.04 2.33 0.53 5.00
91 INT232424 VIP Positive_regulation of Localization of PRL 1 0.36 0 0.53 5.00
92 INT247265 Mecp2 Regulation of Fos 1 0.25 0.38 0.52 5.00
93 INT184922 Negative_regulation of Th Negative_regulation of da 1 0.12 0.18 0.52 5.00
94 INT235390 HTR1A Regulation of BGLAP 1 0.03 0.23 0.51 5.00
95 INT184874 Drd1a Regulation of Gene_expression of Drd2 1 0.13 0.97 0.51 5.00
96 INT271191 Bdnf Regulation of Slc6a4 1 0.03 0.29 0.51 5.00
97 INT223936 HSPG2 Positive_regulation of Gene_expression of Cux1 1 0.03 0 0.46 5.00
98 INT184877 Negative_regulation of Binding of Slc6a3 and ADHD1 1 0.01 0.69 0.45 5.00
99 INT235404 Positive_regulation of RTCA Positive_regulation of Positive_regulation of Prkaca 1 0.00 0.22 0.45 5.00
100 INT223935 HSPG2 Positive_regulation of Cux1 1 0.03 0 0.45 5.00
101 INT235389 Binding of BGLAP and HTR1A 1 0.03 0.15 0.45 5.00
102 INT273945 Crh Positive_regulation of Gene_expression of Crem 1 0.20 0.52 0.43 5.00
103 INT138384 Binding of Htr1b and ADHD1 2 0.07 1.46 0.42 5.00
104 INT232422 VIP Regulation of Gene_expression of PRL 1 0.40 0 0.37 5.00
105 INT232421 Binding of PRL and Positive_regulation of Regulation of ABAT 1 0.09 0 0.37 5.00
106 INT207211 Binding of Creb1 and Crem 2 0.30 1.35 0.36 5.00
107 INT280479 Binding of Mecp2 and Sin3a 1 0.00 1.54 0.35 5.00
108 INT258762 Binding of Dbh and ADHD1 1 0.08 1.61 0.34 5.00
109 INT232419 ABAT Positive_regulation of Localization of PRL 1 0.09 0 0.33 5.00
110 INT232425 Binding of ABAT and Positive_regulation of PRL 1 0.09 0.15 0.33 5.00
111 INT232420 PRL Positive_regulation of Regulation of ABAT 1 0.09 0 0.33 5.00
112 INT207212 Creb1 Regulation of Bdnf 1 0.17 0.92 0.32 5.00
113 INT290826 Binding of hpc and Cort Positive_regulation of hpc 1 0.00 0.79 0.32 5.00
114 INT290854 Binding of hpc and Cort 1 0.01 0.79 0.32 5.00
115 INT290853 Cort Positive_regulation of hpc 1 0.01 0.79 0.32 5.00
116 INT145682 Binding of P2rx4 and P2rx7 2 0.25 0.36 0.31 5.00
117 INT258763 Binding of Drd5 and ADHD1 1 0.07 1.11 0.31 5.00
118 INT258764 Binding of Drd4 and ADHD1 1 0.08 1.11 0.31 5.00
119 INT349951 Grm7 Regulation of pcp 1 0.00 0.56 0.28 5.00
120 INT258766 Binding of Csf2 and ADHD1 1 0.01 0.69 0.27 5.00
121 INT223927 Maoa Regulation of Positive_regulation of Cux1 1 0.24 0.1 0.27 5.00
122 INT273935 Crem Regulation of Gene_expression of Egr2 1 0.05 0.16 0.26 5.00
123 INT223930 Binding of Akt1 and Pik3cb 1 0.07 0.35 0.26 5.00
124 INT223929 Negative_regulation of Binding of Akt1 and Pik3cb 1 0.08 0.36 0.26 5.00
125 INT258757 Binding of Drd2 and Rends1 1 0.00 1.26 0.25 5.00
126 INT290847 Regulation of Binding of Stx1a and Fig4 1 0.05 0.26 0.24 5.00
127 INT290846 Binding of Stx1a and Fig4 1 0.07 0.26 0.22 5.00
128 INT280475 Binding of Bdnf and Mecp2 1 0.11 0.92 0.22 5.00
129 INT280478 Mecp2 Negative_regulation of Gene_expression of Bdnf 1 0.13 0.94 0.22 5.00
130 INT280490 Binding of Bdnf and Mecp2 Negative_regulation of Gene_expression of Bdnf 1 0.15 0.94 0.22 5.00
131 INT290857 PPR Regulation of Fig4 1 0.02 0.45 0.21 5.00
132 INT290855 PPR Regulation of Ca2 1 0.01 0.45 0.2 5.00
133 INT280491 Binding of BDNF and Ntf4 1 0.01 0.14 0.2 5.00
134 INT280474 Binding of Ngf and Ntf4 1 0.00 0.13 0.2 5.00
135 INT280494 Binding of BDNF and Bdnf 1 0.39 0.21 0.2 5.00
136 INT280473 Binding of Ntrk1 and Ntf4 1 0.00 0.13 0.2 5.00
137 INT184868 Binding of Slc6a3 and Lmo1 1 0.02 0.72 0.19 5.00
138 INT280485 Ntrk2 Positive_regulation of Localization of Bdnf 1 0.55 0.45 0.19 5.00
139 INT273723 Binding of Icam1 and Trav6-3 1 0.05 1.97 0.19 5.00
140 INT223477 Binding of Ntrk1 and Ntrk3 2 0.16 0.3 0.19 5.00
141 INT330986 CYP2C9 Positive_regulation of Gene_expression of CYP3A4 1 0.39 0 0.18 5.00
142 INT330985 CYP2C9 Positive_regulation of Gene_expression of CYP2C19 1 0.34 0 0.18 5.00
143 INT290858 Positive_regulation of Ca2 Regulation of PPR 1 0.01 0.5 0.18 5.00
144 INT280487 Negative_regulation of Binding of Mecp2 and Sin3a 1 0.00 0.77 0.18 5.00
145 INT290856 Ca2 Regulation of PPR 1 0.01 0.5 0.18 5.00
146 INT304458 Binding of P2rx4 and P2rx6 1 0.14 0 0.17 5.00
147 INT280486 Binding of Ngfr and Ntrk2 2 0.18 1.21 0.17 5.00
148 INT273715 Positive_regulation of Binding of Icam1 and Trav6-3 1 0.07 1.51 0.16 5.00
149 INT273714 Positive_regulation of Binding of Icam1 and Itgb2 1 0.17 1.46 0.15 5.00
150 INT273717 Binding of Icam1 and Itgb2 1 0.17 1.45 0.15 5.00
151 INT304463 Ass1 Positive_regulation of P2rx4 1 0.01 0 0.14 5.00
152 INT258761 Binding of Slc6a3 and ADHD1 1 0.03 0.51 0.12 5.00
153 INT280488 Bdnf Positive_regulation of Gene_expression of Map3k1 1 0.01 1.49 0.11 5.00
154 INT280484 Bdnf Positive_regulation of Gene_expression of Lhx1 1 0.48 1.49 0.11 5.00
155 INT351427 Binding of PIK3C3 and RYR1 1 0.00 0 0.11 5.00
156 INT258767 Binding of Drd2 and ADHD1 1 0.11 1.14 0.11 5.00
157 INT273018 Binding of FGF9 and PDE1A 1 0.18 0.3 0.11 5.00
158 INT273020 Binding of FGF9 and PDE11A 1 0.22 0.3 0.11 5.00
159 INT280493 Ngfr Regulation of Protein_catabolism of BDNF 1 0.09 0.14 0.1 5.00
160 INT280492 Ntrk1 Regulation of Protein_catabolism of BDNF 1 0.03 0.14 0.1 5.00
161 INT258765 Lmo1 Regulation of ADHD1 1 0.05 1.98 0.09 5.00
162 INT184920 Binding of Agtrap and Slc6a3 1 0.02 0.09 0.09 5.00
163 INT304460 Ass1 Positive_regulation of Xist 1 0.00 0 0.09 5.00
164 INT304464 Binding of P2rx7 and P2rx6 1 0.05 0 0.09 5.00
165 INT258758 Binding of Drd4 and Lmo1 1 0.04 0.64 0.08 5.00
166 INT304462 Binding of P2rx4 and P2rx5 1 0.17 0 0.08 5.00
167 INT247264 Mecp2 Positive_regulation of Gtf2i 1 0.02 0 0.08 5.00
168 INT258756 Binding of Drd5 and Lmo1 1 0.03 0.64 0.08 5.00
169 INT258768 Drd2 Regulation of ADHD1 1 0.14 0.79 0.07 5.00
170 INT304456 Binding of P2rx1 and P2rx4 1 0.14 0 0.07 5.00
171 INT184917 Slc6a3 Positive_regulation of Agtrap 1 0.03 0.08 0.06 5.00
172 INT184924 Ephb1 Positive_regulation of Agtrap 1 0.01 0.08 0.06 5.00
173 INT273944 Negative_regulation of Creb1 Positive_regulation of Positive_regulation of Crem 1 0.26 0.62 0.05 5.00
174 INT304457 Ass1 Positive_regulation of Transcription of P2rx4 1 0.01 0 0.05 5.00
175 INT273719 Binding of Itgb2 and Trav6-3 1 0.07 0.47 0.03 5.00
176 INT273946 Phosphorylation of Creb1 Positive_regulation of Gene_expression of Crem 1 0.29 0 0 5.00
177 INT273722 Binding of Vtcn1 and Trav6-3 1 0.00 0 0 5.00
178 INT273938 Creb1 Positive_regulation of Transcription of Mirg 1 0.01 0.06 0 5.00
179 INT273948 Binding of Creb1 and Pmp2 1 0.04 0 0 5.00
180 INT273952 Creb1 Positive_regulation of Pmp2 1 0.09 0.06 0 5.00
181 INT273949 Binding of Crem and Smarca4 1 0.01 0 0 5.00
182 INT273950 Binding of Crem and Cst8 1 0.10 0 0 5.00
183 INT273943 Creb1 Positive_regulation of Transcription of Crem 1 0.44 0.07 0 5.00
184 INT273716 Binding of Cd28 and Icam1 1 0.09 0 0 5.00
185 INT207210 Binding of Creb1 and Cytip 1 0.18 0.33 0 5.00
186 INT280477 Binding of Bdnf and Sort1 1 0.03 0.08 0 5.00
187 INT273718 Binding of Icam1 and Vtcn1 1 0.00 0 0 5.00
188 INT273720 Binding of Cd28 and Itgb2 1 0.10 0 0 5.00
189 INT304461 Gopc Regulation of Gene_expression of P2rx3 1 0.09 0.07 0 5.00
190 INT273941 Binding of Atf1 and Crem 1 0.15 0 0 5.00
191 INT273957 Binding of Creb1 and Pmp2 Positive_regulation of Gene_expression of Crem 1 0.06 0 0 5.00
192 INT273596 SMG1 Regulation of Negative_regulation of ADHD1 1 0.16 0.41 0 5.00
193 INT304459 Gopc Regulation of Gene_expression of P2rx6 1 0.09 0.07 0 5.00
194 INT280483 Binding of Bdnf and Cpe 1 0.01 0.08 0 5.00
195 INT273951 Phosphorylation of Creb1 Positive_regulation of Pmp2 1 0.06 0.06 0 5.00
196 INT273942 Creb1 Positive_regulation of Gene_expression of Crem 1 0.29 0 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Desipramine. They are ordered first by their pain relevance and then by number of times they were reported in Desipramine. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT102206 Regulation of Bdnf 37 0.62 28.54 28.78 100.00
2 INT147715 Regulation of Gene_expression of Ephb1 6 0.62 5.26 7.49 100.00
3 INT7059 Regulation of Adra2a 89 0.62 18.24 48.43 100.00
4 INT119524 Regulation of Camkk2 4 0.25 1.62 3.35 100.00
5 INT8086 Negative_regulation of Localization of Npy 24 0.59 3.31 12.76 100.00
6 INT118672 Regulation of Camkk1 2 0.56 1.37 2.23 100.00
7 INT135908 Regulation of Negative_regulation of Ephb1 1 0.24 0.4 1.49 100.00
8 INT161 Regulation of Localization of Prl 615 0.62 65.37 298.66 100.00
9 INT43906 Regulation of Tlr4 71 0.53 35.18 15.49 100.00
10 INT27170 Gene_expression of Maoa 13 0.67 3.88 7.5 100.00
11 INT67468 Regulation of SCN5A 27 0.44 4.4 3.47 100.00
12 INT43212 Regulation of Gene_expression of Adra2a 4 0.45 0.24 2.48 100.00
13 INT7340 Regulation of Grin1 87 0.62 30.37 57.93 100.00
14 INT797 Regulation of Penk 812 0.62 111.13 542.24 100.00
15 INT118492 Regulation of Pde4a 7 0.61 6.32 6.04 100.00
16 INT15026 Negative_regulation of Localization of NA 26 0.36 3.76 10.69 100.00
17 INT208244 Regulation of Gene_expression of Ccl5 1 0.26 1.92 1.01 100.00
18 INT79699 Regulation of Cyp2a 1 0.55 0.46 1.62 100.00
19 INT1705 Gene_expression of pCA 126 0.65 88.65 34.81 100.00
20 INT1894 Negative_regulation of Localization of Gh 168 0.58 64.12 43.56 100.00
21 INT89329 Regulation of Gene_expression of Drd3 4 0.61 0.72 3.56 100.00
22 INT146342 Negative_regulation of Negative_regulation of Slc6a3 5 0.44 3.34 3.4 100.00
23 INT161744 Negative_regulation of Negative_regulation of Slc18a2 1 0.40 2.82 0.9 100.00
24 INT161743 Negative_regulation of Gene_expression of Mptp1 1 0.25 2.83 0.89 100.00
25 INT135923 Regulation of Gene_expression of Pde4d 2 0.44 0 0.8 100.00
26 INT152292 Regulation of Gene_expression of Mmp2 6 0.61 3.46 1.76 100.00
27 INT133835 Regulation of Cyp2c6 1 0.45 0 0.69 100.00
28 INT1158 Regulation of Agt 106 0.61 29.4 30.29 100.00
29 INT6127 Regulation of Localization of AVP 60 0.62 15.12 20.84 100.00
30 INT3962 Regulation of AGT 50 0.62 20.96 13.01 100.00
31 INT398 Localization of AGT 45 0.78 16.97 11.54 100.00
32 INT35366 Binding of AR 87 0.47 30.52 8.9 100.00
33 INT12975 Regulation of PLEK 21 0.60 13.62 8.28 100.00
34 INT152286 Regulation of Gene_expression of Mmp9 5 0.36 3.95 2.15 100.00
35 INT160105 Binding of Tst 6 0.31 1.23 1.56 100.00
36 INT128387 Binding of Mpz 2 0.17 0 0.18 100.00
37 INT12441 Positive_regulation of Gpr156 29 0.67 5.7 24.44 99.98
38 INT142831 Positive_regulation of Gene_expression of CREB1 3 0.69 0.08 1.1 99.98
39 INT114657 Positive_regulation of Transcription of Map4 1 0.70 0.33 1.32 99.98
40 INT31774 Positive_regulation of Vta1 67 0.44 14.52 71.79 99.98
41 INT123289 Negative_regulation of Gene_expression of Camkk2 1 0.08 0.62 0.97 99.98
42 INT123297 Negative_regulation of Gene_expression of Camkk1 1 0.54 0.61 0.96 99.98
43 INT116275 Regulation of Gene_expression of Gpr156 2 0.62 0.95 1.62 99.98
44 INT33144 Positive_regulation of Binding of Gabbr2 1 0.69 0.65 1.63 99.98
45 INT50585 Positive_regulation of Line 1 0.40 0 1.02 99.98
46 INT128267 Positive_regulation of Transcription of Slc17a7 1 0.70 0.82 1.9 99.98
47 INT6116 Regulation of Gene_expression of Oprd1 69 0.62 16.43 54 99.98
48 INT128269 Positive_regulation of Slc17a7 3 0.50 1.06 1.82 99.98
49 INT79492 Positive_regulation of Binding of Inadl2 1 0.13 0 1.25 99.98
50 INT14714 Negative_regulation of NPY 10 0.58 4.41 4.52 99.98
51 INT37204 Gene_expression of HCL1 4 0.65 0.76 1.54 99.98
52 INT9660 Regulation of TNF 363 0.62 312.94 139.99 99.96
53 INT2148 Negative_regulation of Oxt 105 0.59 11.42 57 99.96
54 INT7561 Positive_regulation of gr 70 0.57 31.92 20.22 99.96
55 INT52403 Negative_regulation of HTR2B 5 0.42 1.79 3.15 99.96
56 INT52402 Negative_regulation of Htr2c 7 0.42 1.46 4.21 99.96
57 INT7564 Positive_regulation of Nr3c1 16 0.68 4.98 6.25 99.96
58 INT18736 Gene_expression of Ptpn6 19 0.59 4.44 8.06 99.92
59 INT132840 Negative_regulation of Slc6a2 2 0.23 0.7 1.46 99.92
60 INT65235 Negative_regulation of Ads1 4 0.57 0.87 0.49 99.92
61 INT92733 Negative_regulation of Ephb1 19 0.51 8.56 17.72 99.90
62 INT147716 Negative_regulation of Localization of Ephb1 1 0.51 0 0.84 99.90
63 INT214 Localization of AVP 370 0.81 208.51 91.09 99.90
64 INT12440 Regulation of Gpr156 11 0.45 3.2 6.07 99.90
65 INT127113 Positive_regulation of Phosphorylation of Smad2 1 0.68 2.38 2.51 99.90
66 INT13400 Negative_regulation of Enpep 30 0.50 4.23 15.86 99.88
67 INT5228 Positive_regulation of Fos 934 0.70 209.8 503.87 99.86
68 INT52800 Negative_regulation of Gene_expression of Tnf 142 0.59 92.27 55.47 99.86
69 INT123035 Gene_expression of Ephb1 38 0.78 28.84 27.32 99.84
70 INT6107 Localization of Npy 180 0.81 26.76 81.67 99.84
71 INT135909 Positive_regulation of Ephb1 11 0.70 8.94 11.78 99.84
72 INT26116 Gene_expression of Gpr156 31 0.78 13.97 20.59 99.84
73 INT23254 Positive_regulation of Localization of Npy 27 0.65 3.01 11.98 99.84
74 INT3448 Positive_regulation of Gh 521 0.69 180.03 161.18 99.84
75 INT13454 Positive_regulation of Positive_regulation of Gh 49 0.68 14.53 18.49 99.84
76 INT128101 Positive_regulation of Cplx1 1 0.67 0.19 1.18 99.84
77 INT32793 Negative_regulation of Slc6a2 12 0.44 1.8 5.78 99.84
78 INT54065 Positive_regulation of Slc6a2 4 0.69 0.68 4.17 99.82
79 INT61548 Positive_regulation of Fgf2 72 0.70 32.18 14.49 99.82
80 INT54067 Positive_regulation of Positive_regulation of Slc6a2 1 0.69 0 1.46 99.82
81 INT12398 Regulation of Flvcr2 11 0.39 1.8 9.47 99.82
82 INT47683 Negative_regulation of Bdnf 92 0.59 47.53 43.55 99.82
83 INT56047 Negative_regulation of Transcription of Bdnf 16 0.59 8.02 5.67 99.82
84 INT1281 Negative_regulation of Maoa 203 0.59 22.47 91.66 99.80
85 INT1893 Localization of Gh 1041 0.79 340.23 256.58 99.80
86 INT81501 Negative_regulation of Protein_catabolism of Snap25 1 0.30 0.1 0.99 99.80
87 INT886 Gene_expression of Pomc 676 0.78 129.87 295.98 99.80
88 INT74726 Negative_regulation of Slc6a4 61 0.59 21.01 27.84 99.80
89 INT1978 Negative_regulation of Negative_regulation of Maoa 6 0.58 0.58 3.11 99.80
90 INT92669 Gene_expression of Bdnf 309 0.78 178.26 116.68 99.78
91 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 99.78
92 INT6667 Gene_expression of CREB1 27 0.77 6.29 5.84 99.78
93 INT79491 Binding of Inadl2 5 0.17 1.67 5.37 99.78
94 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 99.78
95 INT6699 Positive_regulation of ADRA1D 65 0.70 22.72 20.31 99.78
96 INT12681 Regulation of Trib3 76 0.53 23.92 26.58 99.78
97 INT115407 Transcription of Slc17a7 2 0.72 1.28 3.12 99.78
98 INT3440 Negative_regulation of Localization of Abat 221 0.57 33.94 180.36 99.78
99 INT127112 Phosphorylation of Smad2 19 0.80 11.01 5.36 99.72
100 INT33145 Binding of Gabbr2 1 0.48 0.98 2.48 99.72
101 INT16624 Localization of Grin1 38 0.79 8.46 17.15 99.72
102 INT29503 Gene_expression of Mmp2 95 0.77 56.92 31.68 99.72
103 INT152287 Gene_expression of Tsc22d1 1 0.29 0.35 1.48 99.72
104 INT68975 Gene_expression of Mmp9 111 0.78 79.57 38.55 99.72
105 INT66040 Positive_regulation of Bdnf 114 0.69 67.67 51.81 99.70
106 INT102207 Positive_regulation of Transcription of Bdnf 13 0.69 5.49 7.18 99.70
107 INT209744 Transcription of Gdnf 5 0.67 1.36 2.84 99.70
108 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 99.70
109 INT209745 Positive_regulation of Transcription of Gdnf 4 0.58 0.97 1.91 99.70
110 INT118674 Gene_expression of Camkk1 3 0.71 1.03 1.61 99.70
111 INT123295 Gene_expression of Camkk2 1 0.15 0.62 0.96 99.70
112 INT48890 Gene_expression of Gdnf 91 0.77 28.62 31.49 99.70
113 INT53577 Negative_regulation of Localization of TNF 110 0.59 59.28 35.23 99.68
114 INT89590 Negative_regulation of Gene_expression of Ccl5 8 0.36 3.97 4.67 99.68
115 INT70572 Gene_expression of Fst 33 0.78 5.22 8.24 99.68
116 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 99.68
117 INT739 Negative_regulation of POMC 358 0.59 102.28 166.77 99.68
118 INT123299 Regulation of Transcription of Camkk2 1 0.05 0.41 0.75 99.68
119 INT208247 Negative_regulation of BDP1 1 0.01 0.99 1.02 99.68
120 INT147713 Localization of Ephb1 1 0.70 0 1.54 99.66
121 INT51570 Regulation of Anpep 6 0.43 1.7 2 99.66
122 INT1721 Negative_regulation of HP 148 0.42 86.82 16.89 99.66
123 INT7931 Positive_regulation of Protein_catabolism of Adra2a 1 0.70 0 2.9 99.64
124 INT114662 Transcription of Map4 1 0.72 0.33 1.32 99.64
125 INT89594 Gene_expression of Ccl5 44 0.54 24.08 18.62 99.62
126 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 99.58
127 INT3030 Gene_expression of Adra2a 37 0.68 5.58 19.76 99.58
128 INT7901 Positive_regulation of Ppidl1 14 0.15 1.58 8.8 99.58
129 INT663 Negative_regulation of Adrb3 55 0.59 15.95 14.68 99.54
130 INT85639 Positive_regulation of Tg(CAG-EGFP)D4Nagy 95 0.43 24.83 15.69 99.54
131 INT47741 Negative_regulation of Flvcr2 43 0.51 5.72 23.37 99.54
132 INT6852 Localization of TNF 883 0.81 705.95 270.84 99.52
133 INT45159 Regulation of Nppb 16 0.54 13.57 4.46 99.52
134 INT451 Regulation of Oxt 142 0.62 22.07 69.42 99.52
135 INT108931 Negative_regulation of BDNF 38 0.59 19.61 8.84 99.52
136 INT137721 Regulation of Slc6a2 1 0.20 0.42 1.13 99.52
137 INT102203 Transcription of Bdnf 35 0.71 18.26 20.59 99.50
138 INT11014 Phosphorylation of CREB1 72 0.81 26.35 25.64 99.50
139 INT16580 Negative_regulation of Htr2a 18 0.57 3.8 9.63 99.50
140 INT16261 Transcription of Bdnf 101 0.72 49.41 40.64 99.50
141 INT6115 Positive_regulation of Pigm 82 0.64 16.96 25.73 99.50
142 INT5979 Gene_expression of Oprd1 428 0.78 75.64 320.32 99.50
143 INT5743 Localization of NA 104 0.59 14.35 35.29 99.48
144 INT6576 Localization of Adra2a 11 0.71 1.49 7.18 99.48
145 INT61159 Regulation of Gene_expression of Creb1 46 0.62 24.07 20.52 99.48
146 INT6489 Positive_regulation of Gene_expression of Tnf 140 0.70 92.31 67.85 99.48
147 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58 99.48
148 INT23952 Gene_expression of Cyp2d4 18 0.78 4.76 5.31 99.46
149 INT261231 Negative_regulation of Gene_expression of Cyp2d4 2 0.42 0.36 0.14 99.46
150 INT65733 Positive_regulation of Cnr1 125 0.70 40.27 67.33 99.46
151 INT7932 Protein_catabolism of Adra2a 1 1.00 0 1.44 99.44
152 INT1437 Negative_regulation of Pomc 132 0.59 35.22 60.97 99.44
153 INT6278 Negative_regulation of Gene_expression of Pomc 35 0.59 11.07 14.8 99.44
154 INT55222 Negative_regulation of Gene_expression of Qrfp 5 0.24 1.01 2.72 99.44
155 INT97 Negative_regulation of Adrb1 102 0.59 32.44 26.9 99.40
156 INT16259 Positive_regulation of Bdnf 336 0.70 183.48 209.82 99.40
157 INT32205 Regulation of Positive_regulation of Trib3 9 0.11 2.82 4.1 99.40
158 INT24813 Negative_regulation of Positive_regulation of Trib3 10 0.16 1.3 4.48 99.40
159 INT738 Regulation of POMC 459 0.62 111.19 243.74 99.40
160 INT114188 Negative_regulation of Cort 7 0.41 3.69 2.53 99.40
161 INT149467 Negative_regulation of Avpr1b 2 0.55 4.73 1.16 99.40
162 INT123296 Transcription of Camkk1 1 0.49 0.41 0.75 99.38
163 INT53201 Negative_regulation of gr 35 0.50 17.76 10.62 99.36
164 INT53202 Negative_regulation of Positive_regulation of gr 6 0.46 2.35 2.27 99.36
165 INT96320 Negative_regulation of Transcription of gr 3 0.41 1.38 1.05 99.36
166 INT77249 Positive_regulation of Gene_expression of gr 24 0.67 16.09 8.17 99.34
167 INT77250 Positive_regulation of Gene_expression of Nr3c1 4 0.44 3.32 2.64 99.34
168 INT11009 Phosphorylation of Creb1 458 0.82 111.34 221.97 99.34
169 INT49651 Gene_expression of Creb1 276 0.78 114.77 111.96 99.34
170 INT253 Regulation of PRL 184 0.62 47.27 65.79 99.34
171 INT54707 Positive_regulation of Adrbk1 14 0.67 0.51 9.51 99.32
172 INT50228 Positive_regulation of Positive_regulation of Adora2a 8 0.39 0.1 4 99.32
173 INT13650 Positive_regulation of Gene_expression of Adra2a 6 0.50 0.69 4.94 99.32
174 INT36355 Gene_expression of Mptp1 3 0.39 3.01 0.88 99.32
175 INT75999 Gene_expression of BDNF 344 0.78 114.19 83.12 99.30
176 INT15913 Negative_regulation of CYP2D6 174 0.59 22.45 70.91 99.30
177 INT128844 Transcription of SMARCAL1 1 0.01 0 0.17 99.30
178 INT145681 Regulation of P2rx4 4 0.61 3.41 5.09 99.30
179 INT97984 Negative_regulation of SLC6A4 45 0.59 15.43 18.09 99.28
180 INT10534 Positive_regulation of Trib3 209 0.60 78.75 81.48 99.26
181 INT2229 Positive_regulation of Man2a2 50 0.69 7.47 30.33 99.26
182 INT5202 Positive_regulation of Gene_expression of Fos 1163 0.70 319.28 684 99.26
183 INT1652 Regulation of Pomc 387 0.62 61.01 186.51 99.26
184 INT53388 Negative_regulation of Cyp2c11 18 0.53 2.66 3.11 99.26
185 INT2782 Regulation of Gene_expression of Pomc 75 0.62 15.04 38.97 99.26
186 INT148 Positive_regulation of Gnrhr 182 0.70 47.44 79.64 99.24
187 INT15027 Positive_regulation of Localization of NA 11 0.26 3.4 2.98 99.24
188 INT131219 Gene_expression of Nmi 2 0.52 0.64 1.15 99.24
189 INT153120 Gene_expression of Gnmt 2 0.02 0.17 0.78 99.24
190 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71 99.22
191 INT91994 Regulation of Gene_expression of Gfra1 5 0.42 6 3.6 99.22
192 INT20586 Regulation of Gfra1 20 0.51 9.43 3.41 99.22
193 INT85844 Regulation of Gdnf 18 0.50 11.08 10.43 99.22
194 INT12028 Regulation of Car1 28 0.43 9.01 7.84 99.22
195 INT92001 Regulation of Gene_expression of Gdnf 12 0.62 6.62 6.65 99.22
196 INT20839 Regulation of Car3 12 0.45 4.13 5.97 99.22
197 INT41541 Regulation of Gene_expression of Car1 9 0.41 3.82 3.52 99.22
198 INT50392 Regulation of Ret 6 0.54 3.51 2.22 99.22
199 INT91993 Regulation of Gene_expression of Ret 3 0.42 2.42 0.55 99.22
200 INT91996 Regulation of Gene_expression of Car3 2 0.34 1 0.38 99.22
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