P:Dynorphin

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pChart

Pain Term
Category Molecule
Synonyms None
Pain Specific No
Documents 2483
Hot Single Events 200
Hot Interactions 200

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Dynorphin. They are ordered first by their pain relevance and then by number of times they were reported for Dynorphin. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT40660 Pdyn Positive_regulation of Localization of Prl 1 0.27 0 3.01 100.00
2 INT13940 DNM2 Regulation of Localization of CGA 1 0.11 0 1.86 100.00
3 INT93388 Rbm39 Positive_regulation of Positive_regulation of Pdyn 1 0.03 0.32 1.4 100.00
4 INT26824 Crh Positive_regulation of Localization of Penk 7 0.54 0.42 6.49 100.00
5 INT51205 Binding of OPRK1 and PDYN 7 0.00 2.01 7.8 100.00
6 INT71989 Binding of Pdyn and Insrr 1 0.01 0 1.27 100.00
7 INT71990 Negative_regulation of Binding of Pdyn and Insrr 1 0.01 0 1.27 100.00
8 INT54484 Npepo Positive_regulation of Gene_expression of Fos 1 0.43 0 1.63 100.00
9 INT18793 Crh Regulation of Localization of Penk 1 0.59 0 3.2 100.00
10 INT134294 Binding of Pdyn and Penk 1 0.23 0 2.69 100.00
11 INT86172 Pdyn Positive_regulation of Gene_expression of Il2 1 0.20 0 1.33 100.00
12 INT54490 Npepo Positive_regulation of Gene_expression of Pdyn 1 0.06 0 1.35 100.00
13 INT18791 Crh Regulation of Penk 2 0.49 0 2.15 100.00
14 INT54486 Npepo Positive_regulation of Gene_expression of Rabep2 1 0.14 0 1.08 100.00
15 INT111758 Binding of Drd2 and Insrr 1 0.01 0.94 4.33 100.00
16 INT1310 Pomc Regulation of Localization of Prl 9 0.40 0.61 4.96 100.00
17 INT85743 Pdyn Positive_regulation of Oprk1 3 0.32 2.12 3.52 100.00
18 INT14178 DHCR24 Positive_regulation of Localization of PDYN 1 0.05 0 0.72 100.00
19 INT133946 Binding of DNM2 and OPRK1 1 0.11 0 2.1 100.00
20 INT14177 DHCR24 Positive_regulation of PDYN 1 0.05 0 0.71 100.00
21 INT15842 Crh Positive_regulation of Localization of Pomc 15 0.73 5 5.05 100.00
22 INT151020 Binding of Pdyn and Crh 1 0.14 0.42 1.59 100.00
23 INT89873 Pdyn Positive_regulation of Gene_expression of Gata4 1 0.23 0 1.29 100.00
24 INT89878 Pdyn Positive_regulation of Gene_expression of Nkx2-5 1 0.35 0 1.29 100.00
25 INT89876 Pdyn Positive_regulation of Gata4 1 0.23 0 1.28 100.00
26 INT155497 Oprk1 Negative_regulation of Tenc1 1 0.08 0.34 1.48 100.00
27 INT30146 Binding of Adarb1 and Pdyn 1 0.01 0.17 1.91 100.00
28 INT67383 Binding of OPRK1 and Pdyn 2 0.00 0 1.25 100.00
29 INT41455 Binding of Pomc and Pdyn 1 0.04 0 0.75 100.00
30 INT10268 Binding of PDYN and POMC 11 0.39 0.08 10.36 100.00
31 INT90765 Pcsk2 Positive_regulation of Gene_expression of Pdyn 1 0.41 0 0.39 100.00
32 INT111757 Positive_regulation of Binding of Drd2 and Insrr 1 0.02 0.64 2.89 100.00
33 INT79094 PDYN Positive_regulation of PRL 1 0.35 0.09 1.07 100.00
34 INT40662 Pdyn Regulation of Localization of Prl 1 0.18 0 0.64 100.00
35 INT133933 Binding of DNM2 and TP53INP2 1 0.00 0 1.38 100.00
36 INT85742 Pdyn Positive_regulation of Rbm39 1 0.01 0.17 1.29 100.00
37 INT133937 Binding of OPRK1 and ARFGEF1 1 0.01 0 1.39 100.00
38 INT18663 PDYN Negative_regulation of Binding of Gnrhr 1 0.01 0 0.83 100.00
39 INT114860 Negative_regulation of Insrr Positive_regulation of Casp3 1 0.02 0.71 0.73 100.00
40 INT85744 Binding of Pdyn and Rbm39 1 0.01 0.16 1.12 100.00
41 INT34212 PSG2 Regulation of Localization of Crh 1 0.02 0.09 0.63 100.00
42 INT108438 Grin2b Regulation of Pdyn 1 0.16 0.25 0.9 100.00
43 INT34211 DNM2 Regulation of Localization of Crh 1 0.01 0.09 0.63 100.00
44 INT290551 Crh Positive_regulation of Etf1 1 0.01 0.38 0.73 100.00
45 INT290548 Positive_regulation of Crhr1 Positive_regulation of Etf1 1 0.01 0.38 0.72 100.00
46 INT70603 Penk Positive_regulation of Pdyn 1 0.13 0 1.11 100.00
47 INT73016 PDYN Regulation of TAC1 1 0.29 0.34 1.54 100.00
48 INT51005 PDYN Positive_regulation of IL6 1 0.08 0.84 0.72 100.00
49 INT51006 PDYN Positive_regulation of TNF 1 0.11 0.84 0.72 100.00
50 INT51202 Positive_regulation of Binding of OPRK1 and PDYN 3 0.00 0.63 3.1 100.00
51 INT73398 Binding of Pnoc and Nr1d2 1 0.10 0 1.27 100.00
52 INT2714 Pomc Positive_regulation of Localization of Prl 17 0.79 0.5 8.18 100.00
53 INT31445 ENG Positive_regulation of Localization of Prl 4 0.01 0 1.77 100.00
54 INT1313 Pomc Positive_regulation of Prl 7 0.35 0 4.19 100.00
55 INT31444 ENG Positive_regulation of Prl 1 0.01 0 1.14 100.00
56 INT123009 Oprm1 Positive_regulation of Localization of OR6K2 1 0.00 0 0.59 100.00
57 INT51198 Positive_regulation of Binding of OPRM1 and PDYN 2 0.18 0.3 2.08 100.00
58 INT51199 Binding of OPRM1 and PDYN 2 0.13 0.3 2.08 100.00
59 INT19496 Pomc Regulation of Localization of Ins1 1 0.55 0.33 1.82 100.00
60 INT21424 Binding of Penk and Gtpbp4 1 0.02 0.16 1.2 100.00
61 INT290546 Oprk1 Regulation of Positive_regulation of Anxty 1 0.02 0.42 0.52 100.00
62 INT72416 Binding of PDYN and El2 1 0.45 0 0.58 100.00
63 INT31772 Ednra Positive_regulation of Nppa 1 0.05 0.13 1.33 100.00
64 INT31771 Penk Positive_regulation of Nppa 1 0.22 0.13 1.28 100.00
65 INT31773 Pdyn Positive_regulation of Nppa 1 0.12 0.13 1.27 100.00
66 INT89874 Pdyn Positive_regulation of Localization of Tnfsf14 1 0.26 0 0.66 100.00
67 INT89875 Pdyn Positive_regulation of Localization of Myh6 1 0.09 0 0.66 100.00
68 INT89877 Pdyn Positive_regulation of Nkx2-5 1 0.11 0 0.64 100.00
69 INT48148 Fos Positive_regulation of Gene_expression of Pdyn 1 0.21 0 0.94 100.00
70 INT54304 Il1rl1 Regulation of Regulation of Pdyn 1 0.04 0.23 0.54 100.00
71 INT15984 Binding of Avp and Oxt 11 0.32 1.33 3.64 100.00
72 INT7926 Regulation of Penk Regulation of Trh 1 0.26 0.66 0.8 100.00
73 INT7927 Penk Regulation of Trh 2 0.26 0.66 1.09 100.00
74 INT290543 Binding of Crh and Pdyn 1 0.25 1.04 0.43 100.00
75 INT145908 Pdyn Regulation of Positive_regulation of Casp3 1 0.14 0.94 0.37 100.00
76 INT67445 Oprd1 Regulation of Localization of POMC 1 0.00 0 0.39 100.00
77 INT55164 Binding of NFKB1 and WRAP53 1 0.02 0.11 0.19 100.00
78 INT53823 Cck Regulation of Localization of Pdyn 1 0.09 0 0.95 100.00
79 INT53822 Cck Regulation of Pdyn 1 0.02 0 0.95 100.00
80 INT111760 Dio1 Positive_regulation of Binding of Cpe 1 0.04 0.34 1.44 100.00
81 INT73071 Binding of Cpe and Insrr 3 0.01 0.33 3.38 100.00
82 INT111761 Positive_regulation of Binding of Cpe and Insrr 1 0.01 0.33 1.43 100.00
83 INT73403 Binding of Pdyn and Oprl1 1 0.01 0 0.61 100.00
84 INT111756 Dio1 Positive_regulation of Cpe 1 0.04 0.34 1.42 100.00
85 INT31712 Ptger2 Positive_regulation of Localization of Ins1 1 0.13 0.06 0.49 100.00
86 INT39108 Binding of PDYN and YY1 2 0.50 0.44 2.14 100.00
87 INT133940 Binding of OPRD1 and ARFGEF1 1 0.02 0 0.73 100.00
88 INT133938 Binding of OPRL1 and ARFGEF1 1 0.00 0 0.73 100.00
89 INT133939 Binding of OPRL1 and PDYN 1 0.00 0 0.73 100.00
90 INT133934 Binding of OPRD1 and PDYN 1 0.02 0 0.73 100.00
91 INT133943 Binding of DNM2 and OPRL1 1 0.00 0 0.73 100.00
92 INT133942 Binding of YY1 and ARFGEF1 1 0.05 0 0.69 100.00
93 INT133944 Binding of PDYN and TP53INP2 1 0.00 0 0.69 100.00
94 INT133936 Binding of DNM2 and YY1 1 0.29 0 0.69 100.00
95 INT137958 Asprv1 Positive_regulation of Localization of Pdyn 1 0.21 0 1.43 100.00
96 INT31213 Gnrh1 Positive_regulation of Localization of Pdyn 1 0.07 0 0.37 100.00
97 INT290553 Positive_regulation of Oprk1 Positive_regulation of Crh 1 0.33 0.39 0.72 100.00
98 INT67443 Oprd1 Regulation of Ugt1a10 1 0.00 0 0.36 100.00
99 INT34220 Binding of POMC and Oprl1 4 0.01 0.25 4.05 100.00
100 INT70833 Binding of PDYN and Pnoc 1 0.53 0 0.65 100.00
101 INT36320 PDYN Negative_regulation of Ctsb 1 0.00 0 0.61 100.00
102 INT31443 ENG Positive_regulation of Localization of Pomc 1 0.00 0 0.63 100.00
103 INT81661 Binding of Nfkb1 and Pdyn 1 0.00 0 0.5 100.00
104 INT139987 Oprm1 Positive_regulation of Localization of Oprl1 1 0.16 0.17 1.35 100.00
105 INT26987 Pomc Regulation of Ins1 1 0.40 0 0.87 100.00
106 INT81662 Pdyn Positive_regulation of Nfkb1 1 0.00 0 0.48 100.00
107 INT26984 Cpe Regulation of Ins1 1 0.02 0 0.87 100.00
108 INT69206 Ntf3 Negative_regulation of Ntf3 Positive_regulation of Penk 1 0.05 0.06 0.66 100.00
109 INT69205 Ntf3 Positive_regulation of Penk 1 0.06 0.06 0.66 100.00
110 INT290552 Crh Positive_regulation of Positive_regulation of Pdyn 1 0.38 0.23 0.3 100.00
111 INT114647 Fos Positive_regulation of Gene_expression of PDYN 1 0.48 0.52 0.52 100.00
112 INT51510 Pomc Negative_regulation of Penk 1 0.24 0 0.58 100.00
113 INT26982 Cpe Regulation of Localization of Pomc 1 0.01 0 0.75 100.00
114 INT26983 Cpe Regulation of Localization of Ins1 1 0.02 0 0.75 100.00
115 INT105101 Pdyn Regulation of Samd10 1 0.00 0 1.02 100.00
116 INT6931 Binding of Oprk1 and Pdyn 2 0.24 0.92 1.92 100.00
117 INT29240 Binding of POMC and YY1 5 0.40 0.17 4.06 100.00
118 INT26677 Penk Regulation of Localization of Trh 5 0.50 0 3.05 100.00
119 INT26676 Pomc Regulation of Localization of Trh 3 0.14 0 1.73 100.00
120 INT76396 Il10 Negative_regulation of Il1b 2 0.65 1.89 1.08 100.00
121 INT109065 Pdyn Positive_regulation of Gene_expression of Gata4 1 0.00 0 0.58 100.00
122 INT31861 Cd79b Regulation of Sst 1 0.49 0.31 0.56 100.00
123 INT31862 Pdyn Regulation of Sst 1 0.45 0.31 0.56 100.00
124 INT137699 AR Regulation of PDYN 1 0.46 0.93 0.75 100.00
125 INT240095 Binding of PDYN and Oprk1 1 0.52 1.3 1.22 100.00
126 INT31808 Fam13a Negative_regulation of Oxt 1 0.07 0 0.6 100.00
127 INT290554 Pdyn Positive_regulation of Gpr3 Positive_regulation of Phosphorylation of Oprk1 1 0.17 0.47 0.7 100.00
128 INT31008 Crh Positive_regulation of Pomc 3 0.49 2.31 1.28 100.00
129 INT290547 Pdyn Positive_regulation of Gpr3 1 0.21 0.42 0.7 100.00
130 INT290539 Positive_regulation of Pdyn Positive_regulation of Gpr3 1 0.21 0.42 0.7 100.00
131 INT5451 CRH Regulation of POMC 2 0.28 0.39 0.85 100.00
132 INT31513 Crh Regulation of POMC 3 0.29 5.06 2.78 100.00
133 INT55163 Binding of RELA and WRAP53 1 0.01 0.05 0.1 100.00
134 INT154263 NEUROD1 Positive_regulation of Gene_expression of GAL 1 0.50 0.06 0.63 100.00
135 INT6930 Binding of Oprk1 and Pomc 1 0.08 0.16 1.01 100.00
136 INT30618 Slc3a1 Regulation of ENG 1 0.00 0 0.5 100.00
137 INT30616 Slc3a1 Regulation of Pdyn 1 0.00 0 0.5 100.00
138 INT30619 Pomc Regulation of ENG 1 0.00 0 0.5 100.00
139 INT30617 Pomc Regulation of Pdyn 1 0.00 0 0.5 100.00
140 INT51203 Binding of OPRK1 and OPRM1 2 0.29 0.3 1.36 100.00
141 INT108413 Binding of OPRK1 and Oprd1 1 0.00 0.08 1.04 100.00
142 INT51204 Positive_regulation of Binding of OPRK1 and OPRM1 1 0.38 0.3 1.03 100.00
143 INT145823 Ngf Positive_regulation of Fos 1 0.52 0.95 0.97 100.00
144 INT145824 Negative_regulation of Ngf Positive_regulation of Fos 1 0.48 0.95 0.97 100.00
145 INT131312 Binding of Nts and Datd 1 0.10 0.74 0.46 100.00
146 INT337115 Tg(CAG-EGFP)D4Nagy Positive_regulation of Gene_expression of PDYN 1 0.04 0.07 0.36 100.00
147 INT337114 Tg(CAG-EGFP)D4Nagy Positive_regulation of Gene_expression of TAC1 1 0.04 0.07 0.36 100.00
148 INT30293 POMC Positive_regulation of Gene_expression of IGKV1D-39 1 0.36 0 0.34 100.00
149 INT109067 Pdyn Positive_regulation of Gene_expression of NKX2-5 1 0.01 0 0.29 100.00
150 INT103889 Pdyn Regulation of Gene_expression of Creb1 1 0.03 0.19 0.15 100.00
151 INT79532 Crh Regulation of Ugt1a10 1 0.00 0 0.76 99.98
152 INT7636 RFC1 Negative_regulation of Localization of Oxt 1 0.14 0 0.39 99.98
153 INT7634 RFC1 Negative_regulation of Localization of AVP 1 0.46 0 0.39 99.98
154 INT87812 Penk Regulation of Prl 1 0.16 0 1.34 99.96
155 INT165045 Drd2 Regulation of Cpe 1 0.07 0 0.52 99.96
156 INT31439 Penk Positive_regulation of Localization of Prl 8 0.55 0.23 6.24 99.94
157 INT31440 Penk Positive_regulation of Prl 7 0.76 0 4.1 99.94
158 INT31438 Penk Positive_regulation of Localization of Pomc 1 0.18 0 1.9 99.94
159 INT86171 Oprl1 Positive_regulation of Gene_expression of Il2 1 0.30 0 0.64 99.94
160 INT41108 Adarb1 Positive_regulation of Localization of Ins1 1 0.03 0 0.81 99.92
161 INT7791 Akr1d1 Regulation of Nts 1 0.03 0 1.58 99.92
162 INT7798 Ptgdr Regulation of Nts 1 0.11 0 0.93 99.92
163 INT73838 IGHD4-4 Positive_regulation of CDC42BPG 1 0.00 0 0.71 99.92
164 INT34661 Abat Positive_regulation of Localization of Pomc 1 0.04 0 1.18 99.92
165 INT114009 Pomc Regulation of Binding of Crygs and Oprm1 1 0.03 0 0.56 99.92
166 INT87026 ZAK Positive_regulation of Gene_expression of IL12A 3 0.12 2.55 1.26 99.84
167 INT87025 ZAK Positive_regulation of Gene_expression of IL6 2 0.11 1.59 1.02 99.84
168 INT70757 Binding of Oprl1 and Pnoc 5 0.03 0.23 2.55 99.84
169 INT88194 ZAK Positive_regulation of Gene_expression of IL1B 1 0.07 0.94 0.66 99.84
170 INT87023 ZAK Positive_regulation of Gene_expression of IL36RN 1 0.03 0.62 0.36 99.84
171 INT73402 Binding of Oprl1 and Wdyhv1 1 0.00 0 0.61 99.82
172 INT69666 Binding of OPRL1 and Pnoc 2 0.45 0.06 1.66 99.80
173 INT77142 Binding of IFNG and IL4 2 0.03 1.16 0.95 99.80
174 INT24388 CRH Positive_regulation of Localization of POMC 8 0.51 5.67 3.35 99.80
175 INT31507 FEM1B Positive_regulation of Localization of POMC 1 0.51 0 0.29 99.80
176 INT70925 Binding of Ifng and Il4 2 0.14 0.9 0.5 99.80
177 INT70924 Binding of Il2 and Il4 1 0.07 0.34 0.36 99.80
178 INT88193 Binding of IL2 and IL4 1 0.13 1.7 1.2 99.76
179 INT26986 Cpe Regulation of Pomc 1 0.01 0 0.73 99.76
180 INT26990 Pomc Regulation of Cpe 1 0.01 0 0.73 99.76
181 INT54488 Npepo Regulation of Gene_expression of Jun 1 0.30 0 1.98 99.74
182 INT3434 Vip Positive_regulation of Localization of Prl 6 0.76 0.16 3.21 99.68
183 INT165042 Drd2 Regulation of Tac1 1 0.22 0 0.52 99.68
184 INT29914 FANCB Negative_regulation of Binding of Pomc 1 0.01 0 0.27 99.64
185 INT29599 Binding of Cyp21a1 and Adarb1 1 0.01 0 1.38 99.60
186 INT111762 Positive_regulation of Binding of Cpe and Drd2 1 0.02 0.33 1.42 99.56
187 INT131195 Creb1 Positive_regulation of Positive_regulation of Drd1a 2 0.27 0.61 1.22 99.56
188 INT131194 Creb1 Positive_regulation of Gene_expression of Pdyn 1 0.26 0.08 0.79 99.56
189 INT45306 Pomc Positive_regulation of ENG 2 0.07 1.11 1.68 99.46
190 INT45305 Pomc Positive_regulation of Localization of Avp 1 0.12 0 0.73 99.46
191 INT21425 Binding of Pomc and Gtpbp4 1 0.01 0.1 1.45 99.42
192 INT165043 Drd2 Regulation of Cck 1 0.20 0 0.52 99.42
193 INT41093 Binding of Dbi and Nil 1 0.00 0 0.93 99.40
194 INT7796 Akr1d1 Regulation of Npy 1 0.03 0 1.57 99.40
195 INT11613 Cck Positive_regulation of Localization of Oxt 3 0.53 0 4.17 99.40
196 INT7794 Ptgdr Regulation of Npy 1 0.11 0 0.92 99.40
197 INT7792 Akr1d1 Regulation of Gene_expression of Npy 1 0.02 0 0.65 99.40
198 INT81035 Binding of Oprl1 and Pomc 1 0.03 0.13 0.47 99.40
199 INT111759 Binding of Cpe and Drd2 1 0.01 0.32 1.42 99.36
200 INT98484 Lif Regulation of Gene_expression of Gal 1 0.04 0.16 0.47 99.36

Single Events

The table below shows the top 200 pain related interactions that have been reported for Dynorphin. They are ordered first by their pain relevance and then by number of times they were reported in Dynorphin. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT6822 Gene_expression of Pdyn 215 0.78 35.99 125.76 100.00
2 INT5597 Gene_expression of Pdyn 433 0.78 62.97 235.47 100.00
3 INT796 Gene_expression of Penk 1902 0.78 275.47 1057.59 100.00
4 INT5595 Positive_regulation of Pdyn 223 0.70 48.37 130.14 100.00
5 INT728 Positive_regulation of Penk 1068 0.70 186.9 636.87 100.00
6 INT7028 Localization of Pdyn 90 0.81 8.89 73.54 100.00
7 INT1429 Gene_expression of PDYN 308 0.78 61.33 175.65 100.00
8 INT5594 Regulation of Pdyn 137 0.62 27.04 86.63 100.00
9 INT292 Localization of Penk 876 0.81 88.44 669.14 100.00
10 INT797 Regulation of Penk 812 0.62 111.13 542.24 100.00
11 INT7032 Positive_regulation of Pdyn 94 0.66 26.51 58.83 100.00
12 INT6823 Negative_regulation of Pdyn 68 0.58 13.95 46.12 100.00
13 INT7491 Localization of Pdyn 80 0.81 3.94 58.77 100.00
14 INT7029 Regulation of Pdyn 51 0.61 12.89 40.34 100.00
15 INT5593 Positive_regulation of Gene_expression of Pdyn 114 0.70 29.1 74.46 100.00
16 INT5598 Negative_regulation of Pdyn 95 0.59 14.4 55.43 100.00
17 INT886 Gene_expression of Pomc 676 0.78 129.87 295.98 100.00
18 INT6826 Transcription of Pdyn 130 0.71 22.19 54.88 100.00
19 INT30312 Binding of Pdyn 30 0.37 4.2 18.23 100.00
20 INT4803 Transcription of Penk 435 0.72 59.09 182.4 100.00
21 INT477 Localization of Avp 813 0.81 131.58 300.4 100.00
22 INT12175 Positive_regulation of PDYN 86 0.69 18.27 62.04 100.00
23 INT1652 Regulation of Pomc 387 0.62 61.01 186.51 100.00
24 INT442 Localization of PDYN 99 0.81 11.87 72.75 100.00
25 INT1395 Negative_regulation of Penk 537 0.59 87.33 389.81 100.00
26 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 100.00
27 INT6824 Regulation of Gene_expression of Pdyn 114 0.62 9.48 66.73 100.00
28 INT5136 Negative_regulation of PDYN 71 0.59 11.22 51.14 100.00
29 INT1308 Localization of Pomc 457 0.81 66.83 217.5 100.00
30 INT30245 Binding of Pdyn 26 0.37 2.31 17 100.00
31 INT1273 Gene_expression of Avp 356 0.78 90.56 138.7 100.00
32 INT5610 Positive_regulation of Insr 140 0.69 37.26 86.24 100.00
33 INT2780 Regulation of Gene_expression of Penk 265 0.62 32.45 143.88 100.00
34 INT30276 Positive_regulation of Gene_expression of Pdyn 39 0.67 11.28 24.89 100.00
35 INT8531 Transcription of PDYN 56 0.72 19.51 30.99 100.00
36 INT1510 Binding of PDYN 94 0.48 4.68 56.44 100.00
37 INT10304 Binding of OPRK1 89 0.48 9.28 49.42 100.00
38 INT1562 Localization of Crh 499 0.81 126.74 236.68 100.00
39 INT798 Positive_regulation of Gene_expression of Penk 394 0.70 78.53 203.07 100.00
40 INT5513 Negative_regulation of Pomc 295 0.59 60.9 158.63 100.00
41 INT5202 Positive_regulation of Gene_expression of Fos 1163 0.70 319.28 684 100.00
42 INT5034 Negative_regulation of Insr 100 0.55 28.08 54.5 100.00
43 INT443 Localization of POMC 1020 0.81 284.52 443.17 100.00
44 INT1430 Regulation of PDYN 88 0.60 16.99 60.32 100.00
45 INT7389 Positive_regulation of Localization of Pdyn 15 0.48 1.68 11.88 100.00
46 INT5940 Negative_regulation of Avp 236 0.59 67.86 101.2 100.00
47 INT1212 Binding of Oprl1 312 0.48 28.6 225.15 100.00
48 INT7644 Positive_regulation of Gene_expression of PDYN 27 0.69 10.19 17.47 100.00
49 INT720 Positive_regulation of POMC 807 0.70 237.37 353.83 100.00
50 INT5300 Regulation of Insr 54 0.60 11.33 29.26 100.00
51 INT1396 Binding of Penk 355 0.48 22.79 269.65 100.00
52 INT10119 Positive_regulation of Positive_regulation of Pdyn 14 0.69 2.67 10.81 100.00
53 INT2651 Positive_regulation of Pomc 403 0.70 95.72 206.24 100.00
54 INT7030 Regulation of Gene_expression of Pdyn 23 0.61 5.77 14.18 100.00
55 INT1463 Binding of Pomc 129 0.48 15.89 56.27 100.00
56 INT17915 Gene_expression of Insr 141 0.75 47.45 48.59 100.00
57 INT18032 Positive_regulation of Oprk1 108 0.70 30.78 89.7 100.00
58 INT2555 Positive_regulation of Localization of Penk 116 0.70 24.35 119.73 100.00
59 INT5979 Gene_expression of Oprd1 428 0.78 75.64 320.32 100.00
60 INT29971 Gene_expression of Oprk1 126 0.78 35.32 93.97 100.00
61 INT7031 Transcription of Pdyn 43 0.71 5.82 13.58 100.00
62 INT768 Positive_regulation of Oprl1 179 0.70 40.05 156.93 100.00
63 INT10118 Positive_regulation of Localization of Pdyn 15 0.70 0.77 19.5 100.00
64 INT695 Binding of POMC 304 0.48 56.66 126.85 100.00
65 INT20964 Gene_expression of OPRK1 96 0.78 23.54 58.18 100.00
66 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08 100.00
67 INT10120 Negative_regulation of Positive_regulation of Pdyn 14 0.58 6.05 10.19 100.00
68 INT18460 Positive_regulation of Transcription of PDYN 11 0.67 2.14 6.61 100.00
69 INT4758 Positive_regulation of Localization of Calca 557 0.70 138.55 411.04 100.00
70 INT18428 Protein_catabolism of Pdyn 9 0.92 1.2 6.87 100.00
71 INT4941 Positive_regulation of Oprd1 345 0.70 74.26 304.41 100.00
72 INT5596 Negative_regulation of Gene_expression of Pdyn 41 0.59 5.34 24.36 100.00
73 INT4612 Positive_regulation of Localization of CGA 64 0.64 8.51 22.39 100.00
74 INT1005 Localization of Sst 385 0.81 26.31 244.56 100.00
75 INT1902 Gene_expression of Cck 348 0.78 70.33 241.92 100.00
76 INT159 Negative_regulation of Localization of Prl 416 0.59 55.34 171.8 100.00
77 INT4740 Gene_expression of Th 298 0.78 61.27 154.03 100.00
78 INT2649 Regulation of Calca 433 0.62 146.05 330.95 100.00
79 INT203 Positive_regulation of Pomc 257 0.70 90.56 92.84 100.00
80 INT18430 Positive_regulation of Hps4 14 0.24 0.81 14.82 100.00
81 INT438 Gene_expression of Crh 376 0.78 159.11 169.17 100.00
82 INT28770 Negative_regulation of Gene_expression of PDYN 16 0.57 4.95 12.06 100.00
83 INT30438 Negative_regulation of Gene_expression of Pdyn 8 0.57 1.15 10.46 100.00
84 INT439 Localization of Gnrh1 976 0.81 100.96 363.25 100.00
85 INT6073 Negative_regulation of Localization of Penk 63 0.59 8.67 53.95 100.00
86 INT106095 Localization of Arc 17 0.80 7.61 3.74 100.00
87 INT5497 Positive_regulation of Crh 299 0.70 125.54 131.14 100.00
88 INT18372 Positive_regulation of Transcription of Pdyn 30 0.69 2.48 12.83 100.00
89 INT1047 Negative_regulation of LH 314 0.59 53.71 135.89 100.00
90 INT5501 Regulation of Oprd1 283 0.62 55.1 249.9 100.00
91 INT5660 Binding of Oprd1 477 0.48 71.86 342.06 100.00
92 INT162 Regulation of Prl 794 0.62 165.01 322.24 100.00
93 INT7886 Regulation of Localization of Avp 146 0.62 14.53 72.99 100.00
94 INT5374 Gene_expression of Esr1 412 0.77 263.89 67.34 100.00
95 INT14207 Gene_expression of DNM2 20 0.67 5.76 7.64 100.00
96 INT29105 Positive_regulation of OPRK1 68 0.70 7.06 44.69 100.00
97 INT7884 Regulation of Localization of Oxt 102 0.62 7.95 61.71 100.00
98 INT738 Regulation of POMC 459 0.62 111.19 243.74 100.00
99 INT946 Negative_regulation of Nts 60 0.57 4.61 34.44 100.00
100 INT8962 Gene_expression of Cpe 110 0.71 39.67 71.67 100.00
101 INT19986 Negative_regulation of Cck 31 0.59 4.32 24.99 100.00
102 INT1044 Negative_regulation of Localization of LH 358 0.59 25.95 151.31 100.00
103 INT5957 Positive_regulation of Cpe 65 0.69 21.07 51.22 100.00
104 INT1487 Regulation of Cpe 68 0.62 10.24 52.91 100.00
105 INT161 Regulation of Localization of Prl 615 0.62 65.37 298.66 100.00
106 INT51986 Negative_regulation of Pcsk2 8 0.50 1.4 4.1 100.00
107 INT2149 Positive_regulation of Oxt 181 0.70 24.8 85.43 100.00
108 INT1616 Regulation of Gad1 46 0.61 10.2 28.64 100.00
109 INT1438 Localization of Pomc 360 0.81 101.26 116.47 100.00
110 INT31616 Protein_catabolism of DNM2 5 0.75 1.61 1.63 100.00
111 INT4207 Regulation of Avp 267 0.62 63.72 115.33 100.00
112 INT2699 Binding of Cpe 40 0.48 7.07 33.64 100.00
113 INT54294 Localization of Spnb4 9 0.78 0 18.64 100.00
114 INT2365 Positive_regulation of Cck 354 0.70 87.8 277.41 100.00
115 INT929 Positive_regulation of Oprl1 64 0.70 14.67 52.84 100.00
116 INT18343 Binding of Fam13a 3 0.13 0.18 3.2 100.00
117 INT67441 Positive_regulation of Ugt1a10 3 0.01 0.61 4.22 100.00
118 INT7845 Regulation of OPRK1 44 0.62 4.54 30.49 100.00
119 INT123007 Localization of OR6K2 1 0.01 0 2.87 100.00
120 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84 100.00
121 INT5379 Gene_expression of Fos 656 0.78 255.5 292.54 100.00
122 INT12569 Localization of Oprd1 94 0.81 23.81 104.56 100.00
123 INT1486 Negative_regulation of Cpe 85 0.59 28.78 54.08 100.00
124 INT12232 Regulation of Gene_expression of PDYN 21 0.60 9.91 12.18 100.00
125 INT2909 Positive_regulation of Abat 334 0.70 62.1 256.43 100.00
126 INT3948 Regulation of Cck 291 0.62 58.07 255.88 100.00
127 INT5573 Negative_regulation of Gene_expression of Penk 113 0.59 21.83 64.66 100.00
128 INT1614 Gene_expression of Oprl1 164 0.78 31.43 127.74 100.00
129 INT18585 Regulation of Ugt1a10 4 0.03 0.54 2.69 100.00
130 INT24835 Negative_regulation of Localization of Pdyn 4 0.26 0.31 3.51 100.00
131 INT7584 Gene_expression of Crh 112 0.78 39.15 25.33 100.00
132 INT4868 Gene_expression of GAL 75 0.78 22.23 29.02 100.00
133 INT1307 Positive_regulation of Localization of Pomc 120 0.70 24.58 58.48 100.00
134 INT26670 Regulation of Positive_regulation of Pdyn 11 0.45 0.94 4.96 100.00
135 INT30236 Negative_regulation of Hps4 8 0.15 1.03 11.4 100.00
136 INT4862 Localization of PENK 62 0.81 11.57 40.28 100.00
137 INT17233 Positive_regulation of Localization of PDYN 9 0.69 2.84 10.06 100.00
138 INT30715 Positive_regulation of Binding of Pdyn 1 0.46 0 1.09 100.00
139 INT66531 Gene_expression of Pnoc 88 0.78 22.9 65.11 100.00
140 INT2910 Regulation of Abat 169 0.62 36.95 153.53 100.00
141 INT7489 Negative_regulation of Localization of Pdyn 9 0.59 0.15 5.97 100.00
142 INT7824 Regulation of Cck 39 0.62 5.31 39.28 100.00
143 INT218 Positive_regulation of Th 245 0.70 40.5 120.1 100.00
144 INT1977 Negative_regulation of Positive_regulation of Prl 98 0.59 17.06 47.88 100.00
145 INT5214 Localization of Cpe 49 0.73 13.3 44.36 100.00
146 INT293 Protein_catabolism of Penk 161 1.00 11.71 98.45 100.00
147 INT7490 Regulation of Localization of Pdyn 7 0.62 0.14 11.35 100.00
148 INT7924 Negative_regulation of Pigm 25 0.40 4.51 8.51 100.00
149 INT29107 Regulation of Oprk1 31 0.45 6.16 26.61 100.00
150 INT5959 Protein_catabolism of Cpe 17 0.90 0.98 12.43 100.00
151 INT6825 Negative_regulation of Transcription of Pdyn 12 0.53 0.35 5.22 100.00
152 INT5587 Regulation of Fos 191 0.62 40.81 99.7 100.00
153 INT40993 Negative_regulation of Binding of Xrn1 2 0.41 0 1.99 100.00
154 INT5819 Regulation of Localization of Penk 64 0.62 6.69 57.68 100.00
155 INT7282 Regulation of Localization of Sst 58 0.62 1.92 34.83 100.00
156 INT26788 Gene_expression of Gad1 93 0.78 27.05 42.71 100.00
157 INT1794 Regulation of Localization of CGA 136 0.57 13.39 59.07 100.00
158 INT8388 Positive_regulation of Vip 142 0.70 39.72 67.61 100.00
159 INT7833 Positive_regulation of Cck 33 0.70 8.54 34.21 100.00
160 INT13334 Gene_expression of Drd1a 43 0.62 7.73 24.43 100.00
161 INT12751 Gene_expression of Pigm 91 0.58 22.42 29.2 100.00
162 INT2289 Gene_expression of PENK 203 0.78 55.62 79.49 100.00
163 INT18587 Localization of Ugt1a10 2 0.05 0.17 1.45 100.00
164 INT9987 Gene_expression of Abat 296 0.78 95.46 226.34 100.00
165 INT85741 Regulation of Negative_regulation of Pdyn 3 0.27 0.7 4.15 100.00
166 INT18519 Positive_regulation of Negative_regulation of Pdyn 6 0.47 0.14 8.72 100.00
167 INT5453 Regulation of Localization of POMC 114 0.62 20.56 56.34 100.00
168 INT13943 Localization of DNM2 4 0.52 0.07 2.75 100.00
169 INT13743 Regulation of Gene_expression of Avp 30 0.62 6.9 11.66 100.00
170 INT51779 Gene_expression of Drd1a 46 0.66 11.18 17.51 100.00
171 INT85740 Positive_regulation of Negative_regulation of Pdyn 2 0.18 0.74 2.05 100.00
172 INT403 Localization of Trh 241 0.81 28.55 81.45 100.00
173 INT20345 Gene_expression of Dbi 136 0.78 56.41 46.2 100.00
174 INT72618 Regulation of Tcf3 5 0.44 1.48 3.16 100.00
175 INT124571 Regulation of HPD 3 0.07 1.07 0.89 100.00
176 INT16764 Transcription of Qrfp 39 0.69 6.29 21.61 100.00
177 INT53787 Transcription of Prss12 7 0.21 3.29 4.4 100.00
178 INT72619 Regulation of Rcor2 1 0.34 0.32 2.19 100.00
179 INT7638 Localization of Ptprr 1 0.02 0.97 3.2 100.00
180 INT2783 Gene_expression of Slc3a1 86 0.65 8.84 45.4 100.00
181 INT6765 Localization of Oprl1 49 0.81 5.11 28.87 100.00
182 INT451 Regulation of Oxt 142 0.62 22.07 69.42 100.00
183 INT64440 Gene_expression of Pnoc 66 0.78 13.61 41.76 100.00
184 INT16883 Positive_regulation of Gene_expression of Pigm 11 0.39 3.93 6.89 100.00
185 INT8532 Regulation of Transcription of PDYN 10 0.44 4.97 6.95 100.00
186 INT7344 Gene_expression of TAC1 132 0.75 35.48 68.26 100.00
187 INT30920 Positive_regulation of Gene_expression of Insr 14 0.66 2.91 7.32 100.00
188 INT682 Negative_regulation of AVP 97 0.59 50.67 23.91 100.00
189 INT29964 Positive_regulation of Positive_regulation of PDYN 9 0.67 1.56 11.31 100.00
190 INT72612 Negative_regulation of Regulation of Pdyn 2 0.38 0.77 2.3 100.00
191 INT1711 Negative_regulation of Positive_regulation of Penk 54 0.59 6.55 32.42 100.00
192 INT9012 Localization of Vip 283 0.81 31.71 106.16 100.00
193 INT6108 Gene_expression of Npy 292 0.78 110.65 148.21 100.00
194 INT90903 Positive_regulation of Positive_regulation of Oprk1 13 0.47 3.49 11.18 100.00
195 INT73399 Negative_regulation of Negative_regulation of Wdyhv1 1 0.00 0 0.88 100.00
196 INT1474 Regulation of Localization of Ins1 132 0.61 25.96 43.07 100.00
197 INT16326 Transcription of Gad1 58 0.71 15.78 20.45 100.00
198 INT5993 Positive_regulation of Nts 122 0.70 26.82 70.45 100.00
199 INT5505 Regulation of Localization of Pomc 54 0.61 6.96 30.77 100.00
200 INT4756 Positive_regulation of Nrtim1 37 0.33 14.6 24.12 100.00
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