P:Enkephalin

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pChart

Pain Term
Category Family
Synonyms Enkephalins
Pain Specific Yes
Documents 16039
Hot Single Events 200
Hot Interactions 200

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Enkephalin. They are ordered first by their pain relevance and then by number of times they were reported for Enkephalin. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT10268 Binding of PDYN and POMC 11 0.39 0.08 10.36 100.00
2 INT6078 Pomc Positive_regulation of Localization of Penk 13 0.51 0 15.49 100.00
3 INT10161 Binding of Cck and Penk 6 0.53 0.97 11.15 100.00
4 INT6079 Pomc Positive_regulation of Penk 9 0.43 0 9.46 100.00
5 INT21276 Binding of Oprd1 and Penk 9 0.54 1.14 8.28 100.00
6 INT44716 Binding of ABL2 and PDYN 2 0.40 0.66 4.77 100.00
7 INT36536 PRSS1 Positive_regulation of PENK 1 0.24 0.86 4.39 100.00
8 INT38217 Penk Regulation of Localization of Avp 2 0.38 0.56 4.45 100.00
9 INT2169 Penk Regulation of Localization of Prl 6 0.48 0 4.03 100.00
10 INT9546 Binding of Adarb1 and Penk 5 0.03 0 5.1 100.00
11 INT36535 PRSS1 Positive_regulation of Regulation of PENK 1 0.23 0.54 3.06 100.00
12 INT26824 Crh Positive_regulation of Localization of Penk 7 0.54 0.42 6.49 100.00
13 INT140015 Avp Positive_regulation of Localization of Penk 3 0.63 3.48 6.63 100.00
14 INT30423 Penk Regulation of Localization of Ins1 4 0.26 0.77 4.42 100.00
15 INT34534 Binding of Penk and Oprl1 4 0.37 0 3.64 100.00
16 INT32444 Binding of Cpe and Pomc 2 0.22 0 4.47 100.00
17 INT23280 PRSS1 Positive_regulation of Penk 1 0.05 1.53 2.74 100.00
18 INT91271 Mtr Regulation of Gene_expression of Il6 1 0.20 0 3.17 100.00
19 INT18793 Crh Regulation of Localization of Penk 1 0.59 0 3.2 100.00
20 INT34220 Binding of POMC and Oprl1 4 0.01 0.25 4.05 100.00
21 INT103669 Hps4 Positive_regulation of Mors1 1 0.01 0 2.7 100.00
22 INT70946 Penk Positive_regulation of Hpse 1 0.34 0 2.65 100.00
23 INT20456 Binding of Pomc and Penk 9 0.41 0.26 3.93 100.00
24 INT140014 Avp Negative_regulation of Chkb 1 0.04 1.58 2.86 100.00
25 INT81708 POMC Regulation of Gene_expression of ITGAM 1 0.53 0.72 3.1 100.00
26 INT6076 Negative_regulation of Pomc Positive_regulation of Penk 3 0.31 0 3.14 100.00
27 INT43447 Binding of H3 and Hps4 1 0.07 0 1.82 100.00
28 INT41152 Binding of Penk and Slc3a1 3 0.12 0.11 2.91 100.00
29 INT30345 Pomc Regulation of Localization of Penk 3 0.31 0 2.61 100.00
30 INT51205 Binding of OPRK1 and PDYN 7 0.00 2.01 7.8 100.00
31 INT51497 Cck Negative_regulation of Localization of Trim13 1 0.34 0 4.53 100.00
32 INT29240 Binding of POMC and YY1 5 0.40 0.17 4.06 100.00
33 INT30424 Penk Regulation of Localization of Sst 1 0.20 0 3.1 100.00
34 INT32412 Penk Regulation of Pomc 3 0.21 0.36 1.62 100.00
35 INT140011 Avp Positive_regulation of Dbi 2 0.07 0.93 3.61 100.00
36 INT69770 Penk Negative_regulation of Pscs 1 0.11 0.22 3.39 100.00
37 INT111758 Binding of Drd2 and Insrr 1 0.01 0.94 4.33 100.00
38 INT69556 Slc7a11 Regulation of Cpe 2 0.06 0.46 1.95 100.00
39 INT76651 Cpe Positive_regulation of Gene_expression of Il6 1 0.08 0 1.56 100.00
40 INT76656 POMC Positive_regulation of Gene_expression of Il6 1 0.03 0 1.51 100.00
41 INT62481 Penk Negative_regulation of Slc6a7 2 0.60 0 1.5 100.00
42 INT39950 Binding of ALB and PDYN 1 0.31 0 1.32 100.00
43 INT18355 Penk Positive_regulation of Localization of Sst 1 0.31 0 2.04 100.00
44 INT130333 FUT3 Negative_regulation of Positive_regulation of Tnf 1 0.01 0.36 1.29 100.00
45 INT136200 Binding of Penk and NUP37 1 0.04 0 1.28 100.00
46 INT51202 Positive_regulation of Binding of OPRK1 and PDYN 3 0.00 0.63 3.1 100.00
47 INT18791 Crh Regulation of Penk 2 0.49 0 2.15 100.00
48 INT45269 POMC Negative_regulation of Penk 1 0.01 0 1.24 100.00
49 INT161109 Avp Positive_regulation of Chkb 1 0.12 0.18 4.19 100.00
50 INT143999 IK Regulation of Gene_expression of Penk 1 0.04 0 1.33 100.00
51 INT31440 Penk Positive_regulation of Prl 7 0.76 0 4.1 100.00
52 INT40887 Penk Regulation of Th 1 0.04 0 1.53 100.00
53 INT65025 Binding of Oprm1 and Hps4 1 0.01 0 1.93 100.00
54 INT172757 Rnpep Positive_regulation of Hps4 1 0.00 0 1.08 100.00
55 INT140009 Avp Positive_regulation of Gene_expression of Penk 1 0.40 0.77 1.64 100.00
56 INT23546 Negative_regulation of CNDP2 Negative_regulation of POMC Positive_regulation of POMC 1 0.04 0 1.52 100.00
57 INT23548 Negative_regulation of CNDP2 Negative_regulation of Localization of POMC 1 0.03 0 1.52 100.00
58 INT52205 Prl Positive_regulation of Gene_expression of Penk 1 0.52 0.15 1.25 100.00
59 INT17456 Binding of CSF2 and POMC 3 0.32 4.06 3.15 100.00
60 INT140023 Avp Positive_regulation of Gene_expression of Kitl 1 0.00 0.76 1.62 100.00
61 INT42579 SOD1 Negative_regulation of POMC 1 0.16 0.43 1.27 100.00
62 INT42580 CAT Negative_regulation of POMC 1 0.20 0.42 1.26 100.00
63 INT43446 Binding of Cpe and H3 1 0.02 0 1.25 100.00
64 INT151889 Binding of Adarb1 and DLL1 1 0.00 0 1.66 100.00
65 INT40239 Penk Regulation of Avp 1 0.07 0 1.84 100.00
66 INT40238 Penk Regulation of Oxt 1 0.04 0 1.83 100.00
67 INT2170 Penk Regulation of Localization of LH 2 0.44 0 1.38 100.00
68 INT45665 Fpr1 Negative_regulation of Mme 1 0.13 0 1 100.00
69 INT38579 Binding of POMC and Hps4 1 0.00 0.32 0.99 100.00
70 INT45664 Fpr1 Negative_regulation of Penk 1 0.13 0 0.99 100.00
71 INT107567 Hps4 Positive_regulation of Localization of Il1b 1 0.01 0.09 1.08 100.00
72 INT107564 Hps4 Regulation of Localization of Il1b 1 0.01 0.1 1.07 100.00
73 INT107560 Penk Regulation of Localization of Il1b 1 0.18 0.1 1.07 100.00
74 INT37882 Penk Positive_regulation of LOC100366054 1 0.08 0.35 1.93 100.00
75 INT43814 Binding of Cpe and Oprm1 1 0.08 0 1.41 100.00
76 INT107566 Penk Regulation of Hps4 1 0.00 0.1 1.04 100.00
77 INT107565 Hps4 Regulation of Mtr 1 0.00 0.1 1.04 100.00
78 INT107563 Penk Regulation of Mtr 1 0.00 0.1 1.04 100.00
79 INT107561 Mtr Positive_regulation of Localization of Il1b 1 0.04 0.09 1.09 100.00
80 INT107562 Penk Positive_regulation of Localization of Il1b 1 0.20 0.09 1.09 100.00
81 INT2653 Slc3a1 Regulation of Penk 3 0.04 0.37 1.96 100.00
82 INT17601 Binding of POMC and Oprl1 1 0.01 0 1.2 100.00
83 INT59035 Binding of CPB1 and POMC 1 0.00 0 1.12 100.00
84 INT42728 Binding of PRLR and Cpe 1 0.00 0 2.91 100.00
85 INT7436 CFP Positive_regulation of Binding of POMC 1 0.02 0.18 3.35 100.00
86 INT1310 Pomc Regulation of Localization of Prl 9 0.40 0.61 4.96 100.00
87 INT38453 Binding of Pomc and Penk 1 0.17 0 1.33 100.00
88 INT31439 Penk Positive_regulation of Localization of Prl 8 0.55 0.23 6.24 100.00
89 INT111787 Cck Regulation of Gene_expression of Npr1 1 0.22 1.68 2.57 100.00
90 INT111789 Cck Regulation of Gene_expression of Penk 1 0.49 1.68 2.57 100.00
91 INT111786 Penk Regulation of Gene_expression of Cck 1 0.49 1.66 2.55 100.00
92 INT47342 Penk Regulation of Fabp6 1 0.01 0.39 0.95 100.00
93 INT111757 Positive_regulation of Binding of Drd2 and Insrr 1 0.02 0.64 2.89 100.00
94 INT32839 Binding of Trh and Penk 2 0.42 0 1.63 100.00
95 INT27425 Mtr Positive_regulation of Gene_expression of Il1f5 1 0.06 0 1.3 100.00
96 INT35459 POMC Negative_regulation of Gene_expression of IL16 1 0.45 0 1.19 100.00
97 INT147258 Binding of Tac1 and Penk 1 0.35 0 1.64 100.00
98 INT14576 Tac4 Regulation of Penk 1 0.07 0 1.77 100.00
99 INT81710 POMC Regulation of Gene_expression of FCGR3B 1 0.50 0.34 1.57 100.00
100 INT81709 POMC Regulation of Gene_expression of ITGB2 1 0.40 0.34 1.57 100.00
101 INT81719 POMC Regulation of Gene_expression of ITGAL 1 0.35 0.34 1.57 100.00
102 INT45376 Binding of Cpe and Mme 1 0.07 0.32 2.13 100.00
103 INT2168 Penk Regulation of LH 2 0.32 0.42 0.88 100.00
104 INT81712 POMC Regulation of FCGR3B 1 0.16 0.34 1.56 100.00
105 INT140012 Avp Negative_regulation of Dbi 1 0.06 0.8 1.44 100.00
106 INT81715 POMC Regulation of ITGB2 1 0.40 0.34 1.55 100.00
107 INT81721 POMC Regulation of ITGAM 1 0.39 0.34 1.55 100.00
108 INT73071 Binding of Cpe and Insrr 3 0.01 0.33 3.38 100.00
109 INT81714 POMC Regulation of ITGAL 1 0.15 0.34 1.54 100.00
110 INT42727 Binding of Oprm1 and Trim13 1 0.14 0 2.54 100.00
111 INT134294 Binding of Pdyn and Penk 1 0.23 0 2.69 100.00
112 INT56881 Ppbp Regulation of Vip 1 0.00 0 1.22 100.00
113 INT90050 Binding of GRP and Penk 1 0.06 0 1.06 100.00
114 INT140010 Avp Regulation of Gene_expression of Penk 1 0.25 0.58 1.19 100.00
115 INT70947 Penk Regulation of Hpse 1 0.20 0 0.96 100.00
116 INT26677 Penk Regulation of Localization of Trh 5 0.50 0 3.05 100.00
117 INT60134 MME Negative_regulation of GRP 1 0.20 0 1.12 100.00
118 INT60133 MME Negative_regulation of SST 1 0.10 0 1.12 100.00
119 INT218037 Binding of ALB and Penk 1 0.13 0 0.81 100.00
120 INT34535 Regulation of Binding of Penk and Oprl1 1 0.05 0 1.02 100.00
121 INT40715 Binding of SST and Penk 1 0.10 0 1.02 100.00
122 INT26985 Cpe Negative_regulation of Localization of Ins1 1 0.02 0 1.57 100.00
123 INT24378 Penk Regulation of Oprl1 1 0.10 0 1.29 100.00
124 INT20888 POMC Positive_regulation of Localization of PDYN 1 0.40 0 0.92 100.00
125 INT18099 POMC Positive_regulation of Binding of Prl 1 0.00 0 0.76 100.00
126 INT34294 Penk Positive_regulation of Localization of Crh 1 0.16 0.43 3.19 100.00
127 INT2171 Penk Positive_regulation of Positive_regulation of Gnrh1 1 0.43 0 0.74 100.00
128 INT21415 POMC Positive_regulation of Gene_expression of IL2 1 0.00 0.27 1 100.00
129 INT2167 Penk Positive_regulation of Positive_regulation of LH 1 0.36 0 0.74 100.00
130 INT19819 Penk Regulation of Gene_expression of Ins1 1 0.05 0 1.27 100.00
131 INT14687 Binding of Penk and Ppt1 1 0.41 0 2.46 100.00
132 INT46657 Mtr Regulation of Gnrh1 1 0.01 0 0.71 100.00
133 INT46656 Mtr Regulation of Prl 1 0.05 0 0.7 100.00
134 INT40134 Binding of Pomc and Noc2l 1 0.01 0.08 0.7 100.00
135 INT58678 Binding of Penk and Abat 2 0.40 1.39 1.97 100.00
136 INT41100 Mdk Positive_regulation of Localization of INS 1 0.01 0 1.55 100.00
137 INT45497 PDYN Positive_regulation of TNFRSF10B 1 0.52 0 0.7 100.00
138 INT76652 Cpe Positive_regulation of Il6 1 0.08 0 0.87 100.00
139 INT41101 Mdk Negative_regulation of SST 1 0.02 0 1.53 100.00
140 INT136199 Hnrpd Regulation of Gene_expression of Penk 1 0.46 0 0.74 100.00
141 INT32152 POMC Positive_regulation of Gene_expression of IFNA1 2 0.67 0 1.53 100.00
142 INT84488 Negative_regulation of Binding of Cpe and Mif-ps1 1 0.06 0 1.13 100.00
143 INT84487 Binding of Cpe and Mif-ps1 1 0.05 0 1.13 100.00
144 INT63803 RGD1560349 Positive_regulation of Penk 1 0.04 0 1 100.00
145 INT52206 Prl Regulation of Gene_expression of Penk 2 0.46 0.66 0.75 100.00
146 INT36219 Mme Positive_regulation of Protein_catabolism of Penk 1 0.39 0 0.72 100.00
147 INT30463 Binding of PDYN and Penk 2 0.01 0 1.5 100.00
148 INT110578 PENK Positive_regulation of Gene_expression of MME 1 0.35 0.1 0.76 100.00
149 INT62065 Binding of YY1 and Penk 3 0.14 0 1.69 100.00
150 INT38820 Binding of MTR and PDYN 1 0.03 0.19 0.65 100.00
151 INT87812 Penk Regulation of Prl 1 0.16 0 1.34 100.00
152 INT110577 MME Positive_regulation of Protein_catabolism of POMC 1 0.49 0.06 0.71 100.00
153 INT33989 PENK Negative_regulation of Localization of IGKV1D-39 1 0.01 0.27 0.68 100.00
154 INT30042 Binding of YY1 and Gnrhr 1 0.18 0 1.47 100.00
155 INT46916 Binding of Thop1 and Positive_regulation of Penk 1 0.14 0 0.74 100.00
156 INT46918 Binding of Thop1 and Positive_regulation of Vom1r1 1 0.03 0 0.74 100.00
157 INT66581 Binding of JUN and Rare2 1 0.00 0.07 0.69 100.00
158 INT66582 Binding of FOS and Rare2 1 0.00 0.07 0.69 100.00
159 INT39109 Binding of INSRR and PDYN 1 0.15 0.45 1.46 100.00
160 INT34472 Penk Regulation of Slc3a1 2 0.03 0.42 1.74 100.00
161 INT39108 Binding of PDYN and YY1 2 0.50 0.44 2.14 100.00
162 INT62480 Binding of Penk and Slc6a7 1 0.32 0 0.87 100.00
163 INT62482 Binding of Penk and Slc6a7 Negative_regulation of Slc6a7 1 0.41 0 0.87 100.00
164 INT91270 Oprd1 Regulation of Gene_expression of Il6 1 0.00 0 0.89 100.00
165 INT66580 Binding of Ap1s1 and Rare2 1 0.00 0.07 0.76 100.00
166 INT62478 Binding of Penk and Flvcr2 1 0.09 0 0.87 100.00
167 INT62477 Penk Negative_regulation of Binding of Slc6a7 1 0.44 0 0.86 100.00
168 INT91273 Mtr Positive_regulation of Localization of Il6 1 0.17 0 0.88 100.00
169 INT46917 Binding of Tyr and Positive_regulation of Penk 1 0.02 0 0.73 100.00
170 INT46919 Binding of Tyr and Positive_regulation of Vom1r1 1 0.00 0 0.73 100.00
171 INT46920 Thop1 Regulation of Vom1r1 1 0.03 0 0.74 100.00
172 INT18890 Penk Regulation of Oprd1 1 0.25 0.45 0.97 100.00
173 INT22922 Penk Negative_regulation of Negative_regulation of Cck 1 0.48 0 0.68 100.00
174 INT43717 Positive_regulation of Binding of Trh and Penk 1 0.56 0 0.72 100.00
175 INT23755 Mptp1 Regulation of PDYN 1 0.01 2.27 1.98 100.00
176 INT6415 Binding of Cpe and Oprd1 1 0.00 0 1.07 100.00
177 INT19496 Pomc Regulation of Localization of Ins1 1 0.55 0.33 1.82 100.00
178 INT92721 Positive_regulation of Penk Regulation of OTSC1 1 0.02 0.14 0.71 100.00
179 INT54542 Binding of PENK and SLBP 1 0.07 0 0.59 100.00
180 INT92720 Penk Regulation of OTSC1 1 0.01 0.14 0.7 100.00
181 INT76655 POMC Positive_regulation of Transcription of Il6 1 0.01 0 0.68 100.00
182 INT76654 Cpe Positive_regulation of Transcription of Il6 1 0.05 0 0.68 100.00
183 INT47163 Penk Regulation of Rtcd1 1 0.00 0 1.01 100.00
184 INT123453 Binding of POMC and Penk 1 0.01 0.31 1.23 100.00
185 INT5486 Oprd1 Regulation of Cck 1 0.21 0 2.16 100.00
186 INT54669 Mtr Regulation of Gene_expression of Il1 1 0.02 0.2 0.77 100.00
187 INT54668 Mtr Regulation of Gene_expression of Il1f5 1 0.00 0.2 0.76 100.00
188 INT40900 PDYN Regulation of Localization of POMC 2 0.07 0.56 1.22 100.00
189 INT54844 Negative_regulation of Penk Positive_regulation of Vip 1 0.26 0 1.54 100.00
190 INT144000 Binding of IK and Regulation of Gene_expression of Penk 1 0.04 0 0.67 100.00
191 INT42806 Binding of CCT6A and PENK 1 0.02 0 1.23 100.00
192 INT48101 RT1-DMb Positive_regulation of Penk 1 0.10 0 1.5 100.00
193 INT61860 Akr1d1 Regulation of Egr1 1 0.01 0 0.96 100.00
194 INT61861 Akr1d1 Regulation of Positive_regulation of Egr1 1 0.01 0 0.96 100.00
195 INT20929 Binding of Trim13 and Vas1 1 0.10 0 1.18 100.00
196 INT2700 Binding of App and Cpe 1 0.00 0 0.63 100.00
197 INT7927 Penk Regulation of Trh 2 0.26 0.66 1.09 100.00
198 INT29996 Binding of Oprm1 and Penk 2 0.36 0.4 1.85 100.00
199 INT34052 POMC Regulation of Gene_expression of IFNG 1 0.11 0 1.27 100.00
200 INT30989 Pgrmc1 Positive_regulation of Penk 1 0.00 0 0.57 100.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Enkephalin. They are ordered first by their pain relevance and then by number of times they were reported in Enkephalin. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT796 Gene_expression of Penk 1902 0.78 275.47 1057.59 100.00
2 INT292 Localization of Penk 876 0.81 88.44 669.14 100.00
3 INT728 Positive_regulation of Penk 1068 0.70 186.9 636.87 100.00
4 INT797 Regulation of Penk 812 0.62 111.13 542.24 100.00
5 INT1395 Negative_regulation of Penk 537 0.59 87.33 389.81 100.00
6 INT1396 Binding of Penk 355 0.48 22.79 269.65 100.00
7 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 100.00
8 INT443 Localization of POMC 1020 0.81 284.52 443.17 100.00
9 INT720 Positive_regulation of POMC 807 0.70 237.37 353.83 100.00
10 INT1429 Gene_expression of PDYN 308 0.78 61.33 175.65 100.00
11 INT798 Positive_regulation of Gene_expression of Penk 394 0.70 78.53 203.07 100.00
12 INT4803 Transcription of Penk 435 0.72 59.09 182.4 100.00
13 INT738 Regulation of POMC 459 0.62 111.19 243.74 100.00
14 INT293 Protein_catabolism of Penk 161 1.00 11.71 98.45 100.00
15 INT2780 Regulation of Gene_expression of Penk 265 0.62 32.45 143.88 100.00
16 INT2555 Positive_regulation of Localization of Penk 116 0.70 24.35 119.73 100.00
17 INT739 Negative_regulation of POMC 358 0.59 102.28 166.77 100.00
18 INT695 Binding of POMC 304 0.48 56.66 126.85 100.00
19 INT158 Localization of Prl 2431 0.81 378.96 952.2 100.00
20 INT2289 Gene_expression of PENK 203 0.78 55.62 79.49 100.00
21 INT8962 Gene_expression of Cpe 110 0.71 39.67 71.67 100.00
22 INT442 Localization of PDYN 99 0.81 11.87 72.75 100.00
23 INT5061 Negative_regulation of Mme 306 0.59 51.97 136.9 100.00
24 INT886 Gene_expression of Pomc 676 0.78 129.87 295.98 100.00
25 INT1487 Regulation of Cpe 68 0.62 10.24 52.91 100.00
26 INT1430 Regulation of PDYN 88 0.60 16.99 60.32 100.00
27 INT1510 Binding of PDYN 94 0.48 4.68 56.44 100.00
28 INT5819 Regulation of Localization of Penk 64 0.62 6.69 57.68 100.00
29 INT1308 Localization of Pomc 457 0.81 66.83 217.5 100.00
30 INT477 Localization of Avp 813 0.81 131.58 300.4 100.00
31 INT1486 Negative_regulation of Cpe 85 0.59 28.78 54.08 100.00
32 INT6073 Negative_regulation of Localization of Penk 63 0.59 8.67 53.95 100.00
33 INT2421 Positive_regulation of Positive_regulation of Penk 97 0.69 13.38 55.32 100.00
34 INT5957 Positive_regulation of Cpe 65 0.69 21.07 51.22 100.00
35 INT5597 Gene_expression of Pdyn 433 0.78 62.97 235.47 100.00
36 INT12175 Positive_regulation of PDYN 86 0.69 18.27 62.04 100.00
37 INT5573 Negative_regulation of Gene_expression of Penk 113 0.59 21.83 64.66 100.00
38 INT5660 Binding of Oprd1 477 0.48 71.86 342.06 100.00
39 INT1652 Regulation of Pomc 387 0.62 61.01 186.51 100.00
40 INT5136 Negative_regulation of PDYN 71 0.59 11.22 51.14 100.00
41 INT4862 Localization of PENK 62 0.81 11.57 40.28 100.00
42 INT2651 Positive_regulation of Pomc 403 0.70 95.72 206.24 100.00
43 INT1902 Gene_expression of Cck 348 0.78 70.33 241.92 100.00
44 INT1005 Localization of Sst 385 0.81 26.31 244.56 100.00
45 INT6128 Positive_regulation of Localization of POMC 256 0.70 68.77 121.64 100.00
46 INT5704 Binding of Slc3a1 78 0.43 8.52 51.78 100.00
47 INT4941 Positive_regulation of Oprd1 345 0.70 74.26 304.41 100.00
48 INT1562 Localization of Crh 499 0.81 126.74 236.68 100.00
49 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02 100.00
50 INT5979 Gene_expression of Oprd1 428 0.78 75.64 320.32 100.00
51 INT1212 Binding of Oprl1 312 0.48 28.6 225.15 100.00
52 INT4740 Gene_expression of Th 298 0.78 61.27 154.03 100.00
53 INT10684 Negative_regulation of Protein_catabolism of Penk 41 0.59 2.33 28.63 100.00
54 INT5513 Negative_regulation of Pomc 295 0.59 60.9 158.63 100.00
55 INT438 Gene_expression of Crh 376 0.78 159.11 169.17 100.00
56 INT5852 Gene_expression of Penk 167 0.78 44.44 71.13 100.00
57 INT7287 Positive_regulation of Transcription of Penk 103 0.70 19.81 50.37 100.00
58 INT155 Positive_regulation of Prl 1233 0.70 317.93 457.82 100.00
59 INT5214 Localization of Cpe 49 0.73 13.3 44.36 100.00
60 INT5232 Negative_regulation of Enpep 56 0.57 3.25 26.7 100.00
61 INT5501 Regulation of Oprd1 283 0.62 55.1 249.9 100.00
62 INT3579 Localization of Oxt 555 0.81 43.35 292.44 100.00
63 INT610 Regulation of PENK 47 0.62 14.17 31.55 100.00
64 INT1711 Negative_regulation of Positive_regulation of Penk 54 0.59 6.55 32.42 100.00
65 INT1114 Localization of Ins1 748 0.80 192.95 165.48 100.00
66 INT157 Positive_regulation of Localization of Prl 790 0.70 104.54 374.78 100.00
67 INT2699 Binding of Cpe 40 0.48 7.07 33.64 100.00
68 INT6822 Gene_expression of Pdyn 215 0.78 35.99 125.76 100.00
69 INT439 Localization of Gnrh1 976 0.81 100.96 363.25 100.00
70 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84 100.00
71 INT7692 Positive_regulation of PENK 71 0.70 20.34 32.54 100.00
72 INT9663 Protein_catabolism of PDYN 43 0.99 0.67 16.15 100.00
73 INT1273 Gene_expression of Avp 356 0.78 90.56 138.7 100.00
74 INT1457 Negative_regulation of Binding of Penk 40 0.57 0.25 34.24 100.00
75 INT2290 Protein_catabolism of POMC 41 0.99 4.86 23.36 100.00
76 INT3948 Regulation of Cck 291 0.62 58.07 255.88 100.00
77 INT2640 Gene_expression of Pomc 424 0.78 120.72 155.37 100.00
78 INT3439 Localization of Abat 1017 0.78 112.39 727.06 100.00
79 INT1635 Gene_expression of Vip 245 0.78 53.36 88.13 100.00
80 INT7362 Gene_expression of Sst 185 0.78 41.73 111.37 100.00
81 INT5592 Regulation of Regulation of Penk 36 0.62 4.37 24.02 100.00
82 INT4798 Gene_expression of Nts 169 0.77 29.56 86.04 100.00
83 INT2451 Positive_regulation of Avp 355 0.70 102.66 147.69 100.00
84 INT4937 Negative_regulation of Oprd1 224 0.59 44.51 171.11 100.00
85 INT287 Localization of Cck 518 0.81 86.84 364.04 100.00
86 INT350 Localization of Th 79 0.80 10.26 41.17 100.00
87 INT397 Localization of SST 232 0.81 58.05 101.19 100.00
88 INT5540 Positive_regulation of Oprm1 344 0.70 76.77 319.71 100.00
89 INT5228 Positive_regulation of Fos 934 0.70 209.8 503.87 100.00
90 INT11292 Gene_expression of Mme 77 0.78 20.98 35.85 100.00
91 INT5595 Positive_regulation of Pdyn 223 0.70 48.37 130.14 100.00
92 INT7286 Regulation of Transcription of Penk 81 0.62 9.25 33.45 100.00
93 INT7133 Negative_regulation of MME 85 0.59 29.22 33.1 100.00
94 INT5594 Regulation of Pdyn 137 0.62 27.04 86.63 100.00
95 INT2783 Gene_expression of Slc3a1 86 0.65 8.84 45.4 100.00
96 INT161 Regulation of Localization of Prl 615 0.62 65.37 298.66 100.00
97 INT8346 Gene_expression of Qrfp 136 0.70 19.49 70.21 100.00
98 INT7327 Regulation of Th 164 0.62 29.67 110.14 100.00
99 INT218 Positive_regulation of Th 245 0.70 40.5 120.1 100.00
100 INT6437 Binding of YY1 154 0.47 26.3 90.46 100.00
101 INT1376 Binding of Trh 121 0.48 20 69.86 100.00
102 INT6666 Negative_regulation of PENK 30 0.58 9.16 17.91 100.00
103 INT9012 Localization of Vip 283 0.81 31.71 106.16 100.00
104 INT403 Localization of Trh 241 0.81 28.55 81.45 100.00
105 INT6293 Gene_expression of Oprm1 312 0.78 48.73 215.61 100.00
106 INT12569 Localization of Oprd1 94 0.81 23.81 104.56 100.00
107 INT6108 Gene_expression of Npy 292 0.78 110.65 148.21 100.00
108 INT6174 Regulation of Gene_expression of POMC 49 0.61 9.75 27.69 100.00
109 INT2365 Positive_regulation of Cck 354 0.70 87.8 277.41 100.00
110 INT5993 Positive_regulation of Nts 122 0.70 26.82 70.45 100.00
111 INT2649 Regulation of Calca 433 0.62 146.05 330.95 100.00
112 INT771 Regulation of Nts 93 0.61 13.13 53.57 100.00
113 INT2542 Localization of Calca 2008 0.81 518.3 1408.65 100.00
114 INT20495 Regulation of Protein_catabolism of Penk 17 0.62 0.96 13.3 100.00
115 INT8056 Regulation of Positive_regulation of Penk 34 0.59 4.71 17.66 100.00
116 INT5895 Gene_expression of Oprm1 525 0.78 120.67 407.29 100.00
117 INT1463 Binding of Pomc 129 0.48 15.89 56.27 100.00
118 INT6042 Binding of Oprm1 248 0.48 31.77 154.34 100.00
119 INT5931 Regulation of Oprm1 149 0.62 18.15 125.93 100.00
120 INT5202 Positive_regulation of Gene_expression of Fos 1163 0.70 319.28 684 100.00
121 INT1437 Negative_regulation of Pomc 132 0.59 35.22 60.97 100.00
122 INT2294 Protein_catabolism of PENK 19 1.00 0.64 10.22 100.00
123 INT2155 Negative_regulation of Sst 111 0.59 16.58 77.74 100.00
124 INT11279 Positive_regulation of Penk 65 0.70 18.72 30.29 100.00
125 INT13290 Binding of Atxn2l 34 0.18 1.86 28.16 100.00
126 INT30440 Gene_expression of Hps4 15 0.29 2.39 15.31 100.00
127 INT6406 Binding of Oprm1 280 0.48 40.54 226.26 100.00
128 INT21344 Negative_regulation of Penk 34 0.57 8.83 23.32 100.00
129 INT18430 Positive_regulation of Hps4 14 0.24 0.81 14.82 100.00
130 INT5941 Gene_expression of Oxt 164 0.76 22.63 65.47 100.00
131 INT32718 Gene_expression of OPRD1 82 0.76 9.43 48.38 100.00
132 INT5610 Positive_regulation of Insr 140 0.69 37.26 86.24 100.00
133 INT1197 Negative_regulation of Localization of POMC 109 0.59 28.29 48.02 100.00
134 INT8363 Localization of Nts 135 0.81 14.29 61.71 100.00
135 INT14823 Gene_expression of MET 103 0.75 51.92 32.48 100.00
136 INT5497 Positive_regulation of Crh 299 0.70 125.54 131.14 100.00
137 INT162 Regulation of Prl 794 0.62 165.01 322.24 100.00
138 INT1004 Regulation of Sst 140 0.62 18.52 94.84 100.00
139 INT1196 Positive_regulation of Positive_regulation of POMC 51 0.70 15.99 28.58 100.00
140 INT812 Localization of INS 1026 0.81 515.6 145.31 100.00
141 INT5930 Positive_regulation of Oprm1 221 0.70 31.19 172.93 100.00
142 INT1988 Positive_regulation of Localization of Ins1 254 0.69 59.25 68.37 100.00
143 INT7344 Gene_expression of TAC1 132 0.75 35.48 68.26 100.00
144 INT7028 Localization of Pdyn 90 0.81 8.89 73.54 100.00
145 INT14497 Gene_expression of GRP 82 0.78 17.67 32.27 100.00
146 INT1931 Positive_regulation of Gene_expression of POMC 116 0.70 37.26 38.67 100.00
147 INT22003 Negative_regulation of Cpe 25 0.58 6.23 12.94 100.00
148 INT8691 Localization of Insr 85 0.80 9.27 30.32 100.00
149 INT2366 Binding of Cck 192 0.48 30.64 163.46 100.00
150 INT5940 Negative_regulation of Avp 236 0.59 67.86 101.2 100.00
151 INT1303 Negative_regulation of Npr1 278 0.55 35.1 156.78 100.00
152 INT5453 Regulation of Localization of POMC 114 0.62 20.56 56.34 100.00
153 INT7032 Positive_regulation of Pdyn 94 0.66 26.51 58.83 100.00
154 INT29964 Positive_regulation of Positive_regulation of PDYN 9 0.67 1.56 11.31 100.00
155 INT6824 Regulation of Gene_expression of Pdyn 114 0.62 9.48 66.73 100.00
156 INT1438 Localization of Pomc 360 0.81 101.26 116.47 100.00
157 INT943 Negative_regulation of Cck 205 0.59 38.42 174.78 100.00
158 INT5283 Positive_regulation of Npy 191 0.70 66.77 109.2 100.00
159 INT203 Positive_regulation of Pomc 257 0.70 90.56 92.84 100.00
160 INT1295 Binding of Pomc 85 0.48 12.92 42.8 100.00
161 INT30236 Negative_regulation of Hps4 8 0.15 1.03 11.4 100.00
162 INT1590 Binding of PENK 27 0.47 2.99 12.81 100.00
163 INT4768 Positive_regulation of OPRM1 212 0.70 31.09 164.28 100.00
164 INT5959 Protein_catabolism of Cpe 17 0.90 0.98 12.43 100.00
165 INT4742 Gene_expression of Tac1 177 0.78 69.99 102.66 100.00
166 INT6826 Transcription of Pdyn 130 0.71 22.19 54.88 100.00
167 INT1414 Regulation of Oprl1 169 0.62 32.05 139.99 100.00
168 INT7056 Positive_regulation of Gene_expression of PENK 35 0.70 14.31 18.21 100.00
169 INT15102 Gene_expression of Trim13 18 0.67 0.43 15.49 100.00
170 INT1672 Gene_expression of Mtr 18 0.67 3.39 13.32 100.00
171 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08 100.00
172 INT2122 Negative_regulation of Localization of Gnrh1 226 0.59 26.92 92.04 100.00
173 INT6107 Localization of Npy 180 0.81 26.76 81.67 100.00
174 INT385 Gene_expression of Agt 182 0.78 63.62 37.91 100.00
175 INT5098 Negative_regulation of Localization of Sst 70 0.58 3.56 51.17 100.00
176 INT8223 Transcription of PENK 53 0.69 6.84 14.7 100.00
177 INT4877 Gene_expression of MME 184 0.78 122.82 24.78 100.00
178 INT1377 Positive_regulation of Trh 172 0.70 40.55 69.83 100.00
179 INT946 Negative_regulation of Nts 60 0.57 4.61 34.44 100.00
180 INT90 Localization of Gast 400 0.81 137.67 113 100.00
181 INT20345 Gene_expression of Dbi 136 0.78 56.41 46.2 100.00
182 INT10453 Positive_regulation of Gad1 65 0.70 10.75 31.9 100.00
183 INT20492 Gene_expression of MMP12 89 0.76 81.36 46.12 100.00
184 INT528 Gene_expression of Prl 693 0.78 217.18 192.2 100.00
185 INT1459 Positive_regulation of Binding of Penk 15 0.67 0.08 10.45 100.00
186 INT11624 Gene_expression of OPRM1 445 0.78 72.36 294.36 100.00
187 INT10499 Positive_regulation of Cenpf 11 0.46 1.27 13.42 100.00
188 INT114 Binding of Oprl1 139 0.48 23 103.35 100.00
189 INT8388 Positive_regulation of Vip 142 0.70 39.72 67.61 100.00
190 INT2406 Gene_expression of CCK 85 0.78 28.04 46.67 100.00
191 INT5338 Regulation of Npy 92 0.62 25.54 51.24 100.00
192 INT1474 Regulation of Localization of Ins1 132 0.61 25.96 43.07 100.00
193 INT8347 Gene_expression of SST 181 0.78 104.59 65.45 100.00
194 INT7886 Regulation of Localization of Avp 146 0.62 14.53 72.99 100.00
195 INT1898 Regulation of Crh 220 0.62 61.33 102.64 100.00
196 INT3657 Gene_expression of Ins1 514 0.78 321.69 75.76 100.00
197 INT14031 Gene_expression of Npy 107 0.78 36.48 35.4 100.00
198 INT12392 Regulation of Slc3a1 45 0.36 7.57 25.66 100.00
199 INT339 Regulation of Trh 156 0.62 39.27 83.55 100.00
200 INT5906 Negative_regulation of Oprm1 125 0.59 19.58 101.57 100.00
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