P:Glycine site antagonist

From wiki-pain
Jump to: navigation, search

pChart

Pain Term
Category Drug class
Synonyms Glycine Site Antagonists
Pain Specific No
Documents 34
Hot Single Events 10
Hot Interactions 2

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Glycine site antagonist. They are ordered first by their pain relevance and then by number of times they were reported for Glycine site antagonist. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT13374 Binding of Grin1 and Ltp 1 0.20 0 0.35 93.44
2 INT60935 Negative_regulation of Maoa Negative_regulation of Apcs 1 0.33 0.17 0.46 85.88

Single Events

The table below shows the top 200 pain related interactions that have been reported for Glycine site antagonist. They are ordered first by their pain relevance and then by number of times they were reported in Glycine site antagonist. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT148 Positive_regulation of Gnrhr 182 0.70 47.44 79.64 99.10
2 INT7627 Negative_regulation of Positive_regulation of Ltp 162 0.50 41.2 106.27 98.94
3 INT7114 Positive_regulation of Ltp 1192 0.62 290.76 755.77 98.70
4 INT24141 Negative_regulation of Apcs 24 0.59 16.82 8.29 95.56
5 INT49263 Binding of Grip2 31 0.41 9.86 16.38 95.56
6 INT49538 Binding of Gria1 22 0.47 2.66 13.35 91.92
7 INT7341 Positive_regulation of Grin1 169 0.70 65.86 118.38 90.96
8 INT11246 Binding of Grin1 65 0.48 14.53 36.93 89.60
9 INT13277 Regulation of Positive_regulation of Ltp 83 0.52 19.68 55.78 88.72
10 INT1281 Negative_regulation of Maoa 203 0.59 22.47 91.66 85.88
11 INT43165 Regulation of Positive_regulation of Gnrhr 3 0.27 0.1 1.86 75.96
12 INT88212 Negative_regulation of AP-5 2 0.09 0.28 2.57 75.04
13 INT82496 Negative_regulation of Gv1 1 0.01 0.29 0.71 75.00
14 INT47075 Positive_regulation of Ptger2 142 0.70 78.55 25.47 74.56
15 INT50130 Positive_regulation of Ptger3 13 0.67 5.23 6.47 73.92
16 INT5930 Positive_regulation of Oprm1 221 0.70 31.19 172.93 69.72
17 INT7340 Regulation of Grin1 87 0.62 30.37 57.93 61.16
18 INT65078 Negative_regulation of Pnoc 64 0.59 15.48 59.81 53.60
19 INT7342 Positive_regulation of Positive_regulation of Grin1 18 0.50 9.22 13.76 52.52
20 INT16729 Positive_regulation of LOC308670 10 0.65 1.63 3.11 47.28
21 INT36489 Regulation of Apcs 12 0.58 10.6 2.78 37.28
22 INT7090 Gene_expression of pcp 50 0.66 13.54 8.96 29.96
23 INT2872 Positive_regulation of Maoa 10 0.67 3.26 7.47 25.00
24 INT60933 Positive_regulation of Apcs 16 0.67 11.69 3.68 25.00
25 INT60932 Positive_regulation of Negative_regulation of Apcs 1 0.47 0.07 0.34 25.00
26 INT796 Gene_expression of Penk 1902 0.78 275.47 1057.59 5.00
27 INT16260 Gene_expression of Bdnf 671 0.78 283.44 339.1 5.00
28 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 5.00
29 INT9987 Gene_expression of Abat 296 0.78 95.46 226.34 5.00
30 INT22548 Positive_regulation of Casp3 483 0.70 258.78 213.07 5.00
31 INT16259 Positive_regulation of Bdnf 336 0.70 183.48 209.82 5.00
32 INT798 Positive_regulation of Gene_expression of Penk 394 0.70 78.53 203.07 5.00
33 INT7506 Negative_regulation of Ltp 267 0.46 91.01 176.8 5.00
34 INT49134 Gene_expression of Grin1 270 0.78 84.78 148.61 5.00
35 INT7628 Gene_expression of Ltp 273 0.77 70.21 147.87 5.00
36 INT16253 Positive_regulation of Gene_expression of Bdnf 196 0.70 92.67 113.01 5.00
37 INT74058 Gene_expression of Nos1 260 0.78 80.04 95.71 5.00
38 INT13036 Positive_regulation of Positive_regulation of Ltp 105 0.51 23.71 77.66 5.00
39 INT79506 Gene_expression of Grin2b 122 0.78 43.71 73.42 5.00
40 INT1080 Negative_regulation of Ache 343 0.59 108.51 72.4 5.00
41 INT13276 Regulation of Ltp 107 0.53 30.78 69.13 5.00
42 INT47690 Regulation of Bdnf 118 0.62 53.02 64.5 5.00
43 INT3920 Localization of Ldha 241 0.81 83.08 58.72 5.00
44 INT96533 Gene_expression of Slc1a3 72 0.78 26.85 55.31 5.00
45 INT119528 Positive_regulation of Camk2a 135 0.70 26.13 54.7 5.00
46 INT4957 Negative_regulation of Grin1 87 0.59 24.51 53.21 5.00
47 INT51627 Gene_expression of Grin2a 82 0.76 25.09 47.6 5.00
48 INT374 Positive_regulation of Ldha 212 0.70 107.08 47.43 5.00
49 INT16261 Transcription of Bdnf 101 0.72 49.41 40.64 5.00
50 INT82054 Positive_regulation of Grin2b 56 0.70 17.45 37.14 5.00
51 INT666 Gene_expression of Jun 124 0.78 54.61 33.67 5.00
52 INT73314 Gene_expression of Arc 133 0.78 67.78 27.44 5.00
53 INT80470 Negative_regulation of Gene_expression of Grin1 33 0.59 10.22 27.15 5.00
54 INT32826 Positive_regulation of Gene_expression of Ltp 52 0.45 10.34 26.8 5.00
55 INT63444 Regulation of Gene_expression of Abat 26 0.51 14.65 26.29 5.00
56 INT276 Regulation of Ache 83 0.62 16.75 25.99 5.00
57 INT93485 Negative_regulation of Slc1a2 27 0.59 10.65 20.9 5.00
58 INT107930 Gene_expression of Slc17a7 39 0.78 6.53 18.86 5.00
59 INT90612 Positive_regulation of Grin2a 33 0.65 15.11 18.84 5.00
60 INT4340 Positive_regulation of Localization of Ldha 46 0.70 14.52 15.66 5.00
61 INT11945 Regulation of Chat 38 0.62 7.75 14.97 5.00
62 INT74098 Negative_regulation of Gene_expression of Nos1 36 0.59 16.25 14.82 5.00
63 INT4736 Gene_expression of Chat 67 0.77 17.15 14.24 5.00
64 INT12191 Negative_regulation of Localization of Ldha 35 0.59 13.71 12.35 5.00
65 INT15756 Positive_regulation of Gene_expression of Jun 29 0.69 16.58 12.06 5.00
66 INT56048 Positive_regulation of Transcription of Bdnf 24 0.70 8.33 11.83 5.00
67 INT54466 Negative_regulation of Gene_expression of Ltp 19 0.38 5.44 10.91 5.00
68 INT9027 Positive_regulation of Ddc 24 0.66 6.04 10.19 5.00
69 INT72789 Gene_expression of Cpa1 29 0.50 12.36 9.47 5.00
70 INT119525 Negative_regulation of Positive_regulation of Camk2a 14 0.43 5.15 8.45 5.00
71 INT119940 Positive_regulation of Gene_expression of Arc 36 0.70 18.87 7.85 5.00
72 INT98178 Localization of Casp3 32 0.65 21.01 7.77 5.00
73 INT132468 Positive_regulation of Positive_regulation of Camk2a 20 0.70 2.76 6.7 5.00
74 INT8101 Binding of INCENP 42 0.31 16.2 6.68 5.00
75 INT116641 Phosphorylation of Gsk3a 12 0.71 4.3 6.22 5.00
76 INT37652 Positive_regulation of Pgr 29 0.59 9.09 4.67 5.00
77 INT34822 Regulation of Localization of Ldha 12 0.57 4.03 3.65 5.00
78 INT196779 Phosphorylation of Ppp2ca 28 0.72 1.86 3.25 5.00
79 INT81734 Regulation of Gene_expression of Arc 12 0.43 7.77 3.06 5.00
80 INT90611 Positive_regulation of Positive_regulation of Grin2a 4 0.63 1.89 3 5.00
81 INT21516 Negative_regulation of Positive_regulation of Ldha 13 0.43 4.73 2.53 5.00
82 INT98176 Positive_regulation of Localization of Casp3 7 0.33 6.85 2.12 5.00
83 INT129505 Regulation of Slc17a7 5 0.37 1.09 2.11 5.00
84 INT90272 Gene_expression of Ppp2ca 18 0.68 4.69 2.08 5.00
85 INT128269 Positive_regulation of Slc17a7 3 0.50 1.06 1.82 5.00
86 INT128273 Regulation of Gene_expression of Slc17a7 3 0.62 0.82 1.72 5.00
87 INT261849 Positive_regulation of Phosphorylation of Gsk3a 3 0.14 1.15 1.57 5.00
88 INT57188 Regulation of Gene_expression of Chat 4 0.45 1.89 1.12 5.00
89 INT196753 Negative_regulation of Phosphorylation of Ppp2ca 3 0.37 0.52 0.7 5.00
90 INT196765 Positive_regulation of Gene_expression of Ppp2ca 4 0.44 1.05 0.6 5.00
91 INT261850 Regulation of Positive_regulation of Slc17a7 1 0.10 0.49 0.58 5.00
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox