P:Halothane

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pChart

Pain Term
Category Drug
Synonyms None
Pain Specific No
Documents 5353
Hot Single Events 200
Hot Interactions 25

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Halothane. They are ordered first by their pain relevance and then by number of times they were reported for Halothane. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT68723 Pomgnt1 Negative_regulation of Gene_expression of Fos 1 0.12 0 1.41 100.00
2 INT53177 Spink4 Positive_regulation of Localization of Abat 1 0.33 0 0.74 98.40
3 INT17415 Negative_regulation of TRH Positive_regulation of Prl 1 0.44 0 0.42 98.36
4 INT10549 Prss12 Regulation of Localization of Abat 1 0.04 0 0.43 98.32
5 INT17416 TRH Positive_regulation of Localization of Prl 1 0.47 0 0.85 98.16
6 INT17414 TRH Positive_regulation of Prl 4 0.47 0 1.07 98.16
7 INT50514 CSAD Regulation of Cebpz 1 0.02 0.48 0.38 98.16
8 INT50515 CSAD Positive_regulation of CSAD Regulation of Cebpz 1 0.00 0.48 0.38 98.16
9 INT45736 Prl Positive_regulation of Gene_expression of Gnrhr 1 0.00 0.1 0.56 97.48
10 INT53176 Spink4 Regulation of Localization of Abat 1 0.19 0 1.09 97.08
11 INT391 Binding of Agt and Ace 2 0.33 1.5 0.68 96.16
12 INT20949 Binding of HTN1 and PC 1 0.27 0 0.38 96.12
13 INT57396 Binding of H2 and Bw1 1 0.00 0 0.88 95.40
14 INT57395 Binding of H1 and Bw1 1 0.00 0 0.88 95.40
15 INT179425 Fig4 Regulation of Creb1 1 0.02 0.32 0.28 95.40
16 INT179423 Fig4 Regulation of Mapk3 1 0.02 0.32 0.28 95.40
17 INT90559 Gm5114 Regulation of Abat 1 0.02 0.31 0.87 95.20
18 INT90560 Gm5114 Positive_regulation of Abat 1 0.03 0.25 0.86 95.20
19 INT15578 GNRH1 Regulation of Localization of Lhb 3 0.07 0 1.22 94.52
20 INT10550 Prss12 Positive_regulation of Localization of Abat 1 0.06 0 0.45 92.40
21 INT304824 Binding of Rasa1 and Tnnc1 1 0.01 0 0.13 90.16
22 INT10548 Nts Regulation of Localization of Abat 2 0.14 0 1.42 87.92
23 INT207783 Binding of MRC1 and Ap3d1 1 0.00 2.54 0.22 84.16
24 INT20310 Binding of Hnf1a and Positive_regulation of Transcription of Cyp2e1 1 0.02 0 0.21 83.44
25 INT207784 Ap3d1 Regulation of CACNA1S 1 0.05 0.97 0.16 83.12
26 INT59845 Negative_regulation of IFNA1 Positive_regulation of Gpi1 1 0.09 0 0.37 79.84
27 INT59844 IFNA1 Positive_regulation of Gpi1 1 0.10 0 0.37 79.16
28 INT59843 IFNA1 Positive_regulation of IFNA1 Positive_regulation of Gpi1 1 0.05 0 0.37 79.16
29 INT65946 Ins1 Positive_regulation of Atp2b4 1 0.20 0.46 0.25 78.72
30 INT32761 Positive_regulation of Mrf Positive_regulation of Localization of Vip 1 0.08 0 0.38 72.96
31 INT207785 Binding of RYR1 and Ap3d1 1 0.06 3.24 0.13 72.92
32 INT83903 Penk Positive_regulation of Npff 1 0.49 0 1.02 71.96
33 INT65268 Igf1 Positive_regulation of Col7a1 1 0.48 0 0.3 71.88
34 INT247266 Binding of Mecp2 and Fos 1 0.30 0.18 0.13 70.52
35 INT247267 Binding of Egr1 and Mecp2 1 0.12 0.18 0.13 70.52
36 INT48881 TWIST1 Positive_regulation of Localization of Abat 1 0.02 0.44 1.29 67.64
37 INT65272 Igf1 Positive_regulation of Binding of Col7a1 1 0.42 0 0.14 66.40
38 INT65269 Igf1 Positive_regulation of Gene_expression of Lox 1 0.15 0 0.14 66.40
39 INT207776 Binding of FKBP1A and RYR1 1 0.05 0.59 0.12 62.96
40 INT135905 Binding of NUPR1 and Prl5a1 1 0.01 0 0.47 62.88
41 INT65267 Igf1 Regulation of Gene_expression of Plod3 1 0.07 0 0.13 58.56
42 INT65271 Igf1 Positive_regulation of Gene_expression of Plod3 1 0.12 0 0.13 58.56
43 INT71755 Nppa Regulation of Localization of Alb 1 0.25 1.29 0.11 56.04
44 INT326941 Nts Regulation of Nalcn 1 0.04 0.24 0.23 52.80
45 INT90561 Slc6a1 Negative_regulation of Abat 1 0.02 0.25 0.91 51.92
46 INT63943 Il1b Positive_regulation of Localization of Calca 2 0.46 0.98 0.88 48.20
47 INT217620 Dep1 Positive_regulation of Gene_expression of Tlr4 1 0.20 0.4 0.12 48.04
48 INT326940 Chrm3 Positive_regulation of Nalcn 1 0.06 0.21 0.19 43.36
49 INT254001 Binding of Cxcr4 and Mif 1 0.52 14.17 7.18 35.04
50 INT353337 F2r Positive_regulation of Gene_expression of Mif 1 0.46 0 0 29.92
51 INT170517 Binding of Ryr1 and Qdpr 2 0.15 0.36 0.05 25.68
52 INT257728 Binding of Pbx2 and Vgf 1 0.42 0.18 0.21 21.84
53 INT253994 Cyp3a23/3a1 Positive_regulation of Localization of Mif 1 0.09 0.96 0.69 19.76
54 INT253998 Cyp3a23/3a1 Positive_regulation of Binding of Cxcl12 1 0.10 0.65 0.55 10.32
55 INT253990 Cyp3a23/3a1 Positive_regulation of Cxcl12 1 0.09 0.65 0.55 10.32
56 INT331105 Vmn1r71 Negative_regulation of Mc1r 1 0.04 0.64 2.07 9.44
57 INT172508 Binding of Cnnm1 and Mir343 1 0.01 0.15 1.08 5.36
58 INT179502 Binding of Cd14 and Tlr4 29 0.39 13.77 5.73 5.00
59 INT249566 Binding of Oprd1 and Psmd1 1 0.01 0.82 3.8 5.00
60 INT181455 Binding of Ccr5 and Ccl5 11 0.39 12.13 3.66 5.00
61 INT349583 Aap Positive_regulation of Gene_expression of Cyp2e1 1 0.18 1.57 3.59 5.00
62 INT158770 Binding of Trpv1 and Trpa1 5 0.34 2.07 3.5 5.00
63 INT189488 Binding of Ccr1 and Ccl5 8 0.40 9.26 3.27 5.00
64 INT349584 Binding of Cyp2e1 and Aap 1 0.10 1.56 3.24 5.00
65 INT166134 Binding of Cxcl12 and Cxcr4 3 0.49 5.69 3.17 5.00
66 INT309150 Edc4 Positive_regulation of Creb1 1 0.03 3.46 3.09 5.00
67 INT170367 Binding of Grin1 and Grin2a 5 0.23 1.72 2.79 5.00
68 INT349589 Aap Positive_regulation of Cyp2e1 1 0.21 1.84 2.71 5.00
69 INT223866 Ltp Positive_regulation of Positive_regulation of Mapk1 2 0.46 0.75 2.61 5.00
70 INT189490 Binding of Ccr3 and Ccl5 1 0.33 8.54 2.6 5.00
71 INT253988 Binding of Cd74 and Mif 1 0.36 6.57 2.52 5.00
72 INT249567 Positive_regulation of Binding of Oprd1 and Psmd1 1 0.01 0.66 2.5 5.00
73 INT197379 Tbs1 Positive_regulation of Ltp 6 0.07 1.87 2.21 5.00
74 INT356313 Crh Positive_regulation of Localization of Helt 1 0.02 0 2.11 5.00
75 INT196586 Negative_regulation of Mapk14 Negative_regulation of TNF 2 0.04 2.02 2.08 5.00
76 INT281084 Prkaca Positive_regulation of Mapk1 2 0.25 0 2.06 5.00
77 INT349585 Aap Positive_regulation of Etf1 1 0.00 1.68 1.94 5.00
78 INT227543 Mtx1 Positive_regulation of Prep 1 0.22 1.19 1.92 5.00
79 INT227542 Mtx1 Positive_regulation of Binding of Prep 1 0.23 1.2 1.92 5.00
80 INT95405 Trib3 Positive_regulation of Phosphorylation of Ephb1 3 0.08 1.33 1.89 5.00
81 INT349588 Aap Positive_regulation of Gene_expression of Ros1 1 0.06 0.73 1.85 5.00
82 INT334343 GRP Regulation of Binding of GRP and Helt 1 0.02 0 1.81 5.00
83 INT305741 Binding of Kcnk2 and Sort1 1 0.54 1.01 1.8 5.00
84 INT334345 Binding of GRP and Helt 1 0.02 0 1.79 5.00
85 INT145940 Binding of Gad1 and Abat 2 0.14 1.44 1.78 5.00
86 INT66504 Binding of Agt and Agtr1a 8 0.39 3.78 1.78 5.00
87 INT356327 Crh Positive_regulation of Localization of Gabrg1 1 0.17 0 1.58 5.00
88 INT208980 Binding of Ca2 and Trpv1 4 0.32 0.67 1.55 5.00
89 INT252633 Binding of TNF and Tnfrsf1b 4 0.05 3.66 1.54 5.00
90 INT334347 GRP Positive_regulation of Localization of Gabrg1 1 0.19 0 1.5 5.00
91 INT352196 Igkv12-66 Negative_regulation of Gm10404 1 0.00 1.62 1.34 5.00
92 INT356317 Crhr1 Regulation of Gene_expression of Cea 1 0.18 0.65 1.33 5.00
93 INT249565 Binding of Gabrg1 and Oprd1 1 0.00 0.1 1.33 5.00
94 INT356326 Crhr1 Regulation of Gene_expression of Helt 1 0.01 0.65 1.32 5.00
95 INT253999 Binding of Cxcl12 and Mif 1 0.41 2.26 1.22 5.00
96 INT197231 Grik1 Regulation of Gabrg1 1 0.19 0.13 1.22 5.00
97 INT285185 Binding of Ca2 and Cd2 1 0.25 0.24 1.21 5.00
98 INT228681 Fkbp4 Negative_regulation of Trib3 1 0.00 0.57 1.2 5.00
99 INT349587 Binding of Aap and Csf2 1 0.04 0.41 1.18 5.00
100 INT228680 Fkbp1a Negative_regulation of Trib3 1 0.01 0.56 1.18 5.00
101 INT349586 Aap Regulation of Gene_expression of Ros1 1 0.03 0.56 1.17 5.00
102 INT353338 F2r Positive_regulation of Localization of Mif 1 0.68 1.25 1.16 5.00
103 INT349590 Aap Positive_regulation of Cytl1 1 0.13 1.31 1.15 5.00
104 INT208621 Binding of Prph and Nmbr 1 0.05 0.43 1.12 5.00
105 INT229913 Positive_regulation of Ntsr1 Positive_regulation of Gene_expression of Egr1 1 0.12 1.33 1.11 5.00
106 INT193328 Grid1 Regulation of Positive_regulation of Prkcg 1 0.00 0.1 1.1 5.00
107 INT305734 Binding of Sort1 and Trpv1 1 0.01 0.5 1.08 5.00
108 INT223875 Negative_regulation of Mapk8 Negative_regulation of Positive_regulation of Ltp 1 0.31 0 1.07 5.00
109 INT356316 Crh Positive_regulation of Localization of Cea 1 0.34 0 1.06 5.00
110 INT331108 Mc1r Positive_regulation of Mc4r 1 0.44 1.05 1.06 5.00
111 INT292531 Il10 Negative_regulation of Positive_regulation of Mapk14 1 0.15 1.13 1.06 5.00
112 INT317552 Binding of Calm3 and Car2 2 0.06 0.07 1.05 5.00
113 INT331107 Vmn1r71 Positive_regulation of Mc1r 1 0.05 0.5 1.05 5.00
114 INT214875 Ap3d1 Negative_regulation of Gene_expression of Fos 1 0.00 0.39 1.04 5.00
115 INT346835 Gene_expression of Efnb2 Positive_regulation of Phosphorylation of Grin2b 1 0.27 1.07 1.03 5.00
116 INT349576 Binding of Ugt2b and Sult1a1 1 0.00 0.45 1.03 5.00
117 INT229914 Egr1 Positive_regulation of Phosphorylation of Mapk3 1 0.46 1.03 1.02 5.00
118 INT349592 GTF2H5 Negative_regulation of Cyp2c22 1 0.00 0.64 0.98 5.00
119 INT292530 Il10 Negative_regulation of Localization of Il1a 1 0.06 1.09 0.97 5.00
120 INT227545 Hspa9 Positive_regulation of Prep 1 0.18 0.59 0.96 5.00
121 INT252877 Prkaca Positive_regulation of Regulation of Grip2 1 0.01 0.22 0.94 5.00
122 INT331109 Tpnr1 Regulation of Gene_expression of Calca 1 0.06 0.97 0.94 5.00
123 INT252878 Prkaca Regulation of Regulation of Grip2 1 0.01 0.22 0.94 5.00
124 INT336017 Vip Regulation of Tlr4 1 0.22 1.23 0.93 5.00
125 INT132610 Bdnf Positive_regulation of Ntrk2 4 0.46 1.09 0.93 5.00
126 INT223871 Ltp Positive_regulation of Gene_expression of Mapk1 1 0.33 0 0.93 5.00
127 INT252880 Positive_regulation of Prkaca Positive_regulation of Gene_expression of Tacr1 1 0.02 0.29 0.92 5.00
128 INT252879 Creb1 Positive_regulation of Gene_expression of Tacr1 1 0.03 0.24 0.91 5.00
129 INT72917 Binding of Crh and Crhr1 4 0.32 0.73 0.91 5.00
130 INT219037 Creb1 Positive_regulation of Transcription of Bdnf 2 0.43 1.07 0.9 5.00
131 INT309140 Dlat Positive_regulation of Creb1 1 0.06 1.1 0.9 5.00
132 INT252876 Positive_regulation of Prkaca Regulation of Gene_expression of Tacr1 1 0.01 0.28 0.89 5.00
133 INT276964 Binding of Tlr1 and Tlr2 11 0.24 4.22 0.89 5.00
134 INT253992 Cxcl12 Positive_regulation of Mif 1 0.46 1.31 0.88 5.00
135 INT305742 Binding of Sort1 and Gtf3a 1 0.01 0.64 0.88 5.00
136 INT252881 Crcp Positive_regulation of Gene_expression of Tacr1 1 0.00 0.28 0.88 5.00
137 INT223867 Camk2a Positive_regulation of Positive_regulation of Ltp 1 0.25 0 0.87 5.00
138 INT254004 Cxcl12 Positive_regulation of Cxcr4 1 0.47 1.29 0.86 5.00
139 INT196578 Ephb1 Positive_regulation of Phosphorylation of Mapk9 1 0.13 0.5 0.85 5.00
140 INT196576 Trib3 Positive_regulation of Phosphorylation of Mapk9 1 0.02 0.5 0.85 5.00
141 INT253995 Binding of Cxcl12 and Cyp3a23/3a1 1 0.06 1.28 0.85 5.00
142 INT235087 NOS1 Positive_regulation of Localization of ABAT 1 0.02 0.61 0.81 5.00
143 INT352201 Negative_regulation of ALOX5 Negative_regulation of Cpox 1 0.02 0.89 0.81 5.00
144 INT182839 Camk4 Positive_regulation of Creb1 3 0.49 1.81 0.79 5.00
145 INT276988 Binding of Tlr6 and Tlr2 11 0.26 4.89 0.79 5.00
146 INT222024 Mapk8 Regulation of Mapk14 2 0.17 0.83 0.79 5.00
147 INT196577 Negative_regulation of Mapk14 Negative_regulation of Il6 1 0.13 0.45 0.78 5.00
148 INT214876 Ap3d1 Negative_regulation of Gria1 1 0.00 0.4 0.78 5.00
149 INT196574 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il6 1 0.13 0.45 0.78 5.00
150 INT224281 Bdnf Regulation of Gene_expression of Gap43 1 0.36 0.4 0.77 5.00
151 INT196575 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il1a 1 0.04 0.44 0.77 5.00
152 INT190788 Adcy8 Positive_regulation of Adcy1 1 0.23 0.77 0.77 5.00
153 INT224280 Bdnf Positive_regulation of Creb1 3 0.30 0.62 0.77 5.00
154 INT224283 Bdnf Regulation of Gene_expression of Calca 1 0.19 0.35 0.76 5.00
155 INT356324 ORF61 Regulation of Localization of Gabrg1 1 0.00 0.19 0.76 5.00
156 INT298730 PROC Positive_regulation of Gene_expression of Ngf 1 0.00 0.6 0.74 5.00
157 INT335592 Ltp Positive_regulation of Positive_regulation of Akt1 1 0.01 0.19 0.74 5.00
158 INT334348 GRP Regulation of Helt 1 0.01 0 0.72 5.00
159 INT307754 Ik Negative_regulation of Trpa1 1 0.07 0.08 0.71 5.00
160 INT223873 Mapk8 Regulation of Positive_regulation of Ltp 1 0.24 0 0.71 5.00
161 INT89936 Tlr4 Positive_regulation of Il6 3 0.49 0.95 0.7 5.00
162 INT335596 Positive_regulation of Grin2b Positive_regulation of Positive_regulation of Car2 1 0.12 0.19 0.69 5.00
163 INT215098 Tlr4 Positive_regulation of Localization of Il6 3 0.18 1.18 0.69 5.00
164 INT223868 Mapk1 Positive_regulation of Creb1 2 0.17 0.34 0.68 5.00
165 INT223876 Mapk1 Positive_regulation of Atf6b 1 0.10 0 0.68 5.00
166 INT223869 Mapk8 Negative_regulation of Positive_regulation of Ltp 1 0.20 0 0.68 5.00
167 INT298728 Akt1 Positive_regulation of Rela 1 0.01 1.03 0.67 5.00
168 INT309123 Edc4 Positive_regulation of Car1 1 0.02 0.51 0.66 5.00
169 INT335591 Binding of Camk4 and Ltp 1 0.30 0 0.65 5.00
170 INT335588 Positive_regulation of Binding of Camk4 and Ltp 1 0.39 0 0.65 5.00
171 INT335595 Camk4 Regulation of Fam82b 1 0.04 0.48 0.64 5.00
172 INT356329 Crhr1 Regulation of Cea 1 0.09 0.31 0.64 5.00
173 INT235082 CA2 Positive_regulation of NOS1 2 0.11 0.62 0.63 5.00
174 INT356314 Binding of Crhr1 and ORF61 1 0.00 0 0.63 5.00
175 INT335590 Camk4 Regulation of Ablim1 1 0.04 0.48 0.62 5.00
176 INT223864 Tbs1 Positive_regulation of Gopc 1 0.03 0 0.61 5.00
177 INT257717 Binding of Bdnf and Vgf 1 0.25 0.86 0.61 5.00
178 INT309158 Binding of Esr1 and Dlat 1 0.04 1.39 0.61 5.00
179 INT227544 Hspa9 Regulation of Gene_expression of Prep 1 0.15 0.57 0.61 5.00
180 INT324065 Ptger2 Positive_regulation of Prkaca 2 0.24 0.63 0.61 5.00
181 INT356328 Crh Positive_regulation of Cea 1 0.26 0.28 0.6 5.00
182 INT201294 Negative_regulation of Grik1 Negative_regulation of Gabrg1 1 0.30 0 0.6 5.00
183 INT172511 Mir343 Positive_regulation of ECT 1 0.04 0.08 0.6 5.00
184 INT223865 Enpep Positive_regulation of Ltp 1 0.02 0 0.59 5.00
185 INT250054 Positive_regulation of Binding of Gpr143 and Spdya 1 0.04 0.52 0.59 5.00
186 INT250053 Binding of Gpr143 and Spdya 1 0.03 0.51 0.59 5.00
187 INT356315 Crh Regulation of Cea 1 0.16 0.08 0.58 5.00
188 INT356311 Crh Regulation of Gabrg1 1 0.08 0.08 0.57 5.00
189 INT356320 ORF61 Positive_regulation of Positive_regulation of Prkaca 1 0.01 0.05 0.57 5.00
190 INT257715 Bdnf Positive_regulation of Transcription of Vgf 1 0.35 0.66 0.57 5.00
191 INT257713 Ngf Positive_regulation of Transcription of Vgf 1 0.41 0.66 0.57 5.00
192 INT305744 Fst Positive_regulation of Creb1 1 0.12 0.33 0.57 5.00
193 INT305732 Tst Positive_regulation of Creb1 1 0.12 0.33 0.57 5.00
194 INT356321 Positive_regulation of Crhr1 Positive_regulation of Cea 1 0.19 0.37 0.56 5.00
195 INT296169 Binding of Htr4 and Creb1 1 0.49 0.1 0.56 5.00
196 INT298729 PROC Positive_regulation of Set 1 0.00 0.76 0.55 5.00
197 INT196585 Mapk14 Regulation of TNF 1 0.02 0.36 0.55 5.00
198 INT334346 GRP Regulation of Gene_expression of Helt 1 0.03 0 0.55 5.00
199 INT356322 Positive_regulation of Crhr1 Positive_regulation of ORF61 1 0.00 0 0.54 5.00
200 INT204494 Binding of App and Fmr1 1 0.54 4.39 0.54 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Halothane. They are ordered first by their pain relevance and then by number of times they were reported in Halothane. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT5591 Regulation of Gene_expression of Fos 425 0.62 129.06 265.78 100.00
2 INT3971 Positive_regulation of Alb 175 0.70 98.46 36.45 100.00
3 INT15542 Negative_regulation of CASP8 20 0.41 17.3 5.63 100.00
4 INT797 Regulation of Penk 812 0.62 111.13 542.24 100.00
5 INT2330 Regulation of CB 78 0.10 20.46 32.6 100.00
6 INT3441 Regulation of Localization of Abat 117 0.38 8.67 87.59 100.00
7 INT2910 Regulation of Abat 169 0.62 36.95 153.53 100.00
8 INT18088 Binding of Tspo 26 0.48 9.12 10.2 100.00
9 INT10026 Positive_regulation of Gtpc 3 0.05 0.27 1.01 100.00
10 INT9477 Regulation of Gene_expression of Junb 5 0.45 0.88 1.15 100.00
11 INT162 Regulation of Prl 794 0.62 165.01 322.24 100.00
12 INT15544 Regulation of CASP8 6 0.41 5.83 1.63 100.00
13 INT81827 Positive_regulation of Kcnk2 7 0.70 0.42 1.79 100.00
14 INT15541 Positive_regulation of Negative_regulation of CASP8 2 0.31 1.23 1.31 100.00
15 INT15543 Gene_expression of CASP8 32 0.75 25.6 2.61 100.00
16 INT23178 Gene_expression of H1 38 0.68 13.37 9.09 100.00
17 INT6127 Regulation of Localization of AVP 60 0.62 15.12 20.84 100.00
18 INT34594 Negative_regulation of Gene_expression of ALPP 12 0.50 5.04 1.41 100.00
19 INT59244 Regulation of Pla2g2a 5 0.57 3.02 1.82 100.00
20 INT23128 Binding of PTGER1 4 0.27 1.82 2.45 100.00
21 INT6578 Regulation of Pla2g1b 11 0.49 3.94 3.19 100.00
22 INT81694 Regulation of Positive_regulation of Pla2g2a 1 0.43 0 0.44 100.00
23 INT6824 Regulation of Gene_expression of Pdyn 114 0.62 9.48 66.73 100.00
24 INT639 Regulation of LAMC2 8 0.44 4.68 2.92 100.00
25 INT1530 Regulation of Gh 382 0.61 115.96 112.47 100.00
26 INT12474 Regulation of INSRR 18 0.29 6.29 4.81 100.00
27 INT324485 Negative_regulation of Drsi 1 0.02 0 0.43 100.00
28 INT78306 Regulation of Positive_regulation of EIF2C2 1 0.01 0.2 1 100.00
29 INT8153 Regulation of Localization of Cck 52 0.62 11.22 54.83 100.00
30 INT45824 Regulation of Positive_regulation of Abat 6 0.24 1.2 5.16 100.00
31 INT3157 Gene_expression of Gtpc 1 0.00 0.07 0.18 100.00
32 INT7845 Regulation of OPRK1 44 0.62 4.54 30.49 100.00
33 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57 100.00
34 INT58934 Negative_regulation of Srn1 3 0.16 0.19 0.84 100.00
35 INT20117 Regulation of Imacq 2 0.14 0 1 100.00
36 INT1864 Regulation of Bche 18 0.47 6.18 2.44 100.00
37 INT3978 Regulation of Regulation of cerebral blood flow 2 0.00 0.57 1.16 100.00
38 INT30039 Negative_regulation of HAL 7 0.42 4.32 1.61 100.00
39 INT36199 Regulation of SERPINA7 1 0.12 0 0.86 100.00
40 INT2085 Positive_regulation of LH 441 0.70 60.15 191.02 100.00
41 INT71568 Regulation of Protein_catabolism of Map2 1 0.45 0.8 0.58 100.00
42 INT169252 Negative_regulation of Gene_expression of Kcnk1 1 0.41 0 0.42 100.00
43 INT169249 Negative_regulation of Gene_expression of Kcnk13 1 0.15 0 0.42 100.00
44 INT159 Negative_regulation of Localization of Prl 416 0.59 55.34 171.8 99.98
45 INT27591 Negative_regulation of Gene_expression of Alb 30 0.58 17.03 5.99 99.98
46 INT6056 Negative_regulation of Gene_expression of Fos 601 0.59 193.05 386.84 99.98
47 INT5202 Positive_regulation of Gene_expression of Fos 1163 0.70 319.28 684 99.98
48 INT703 Positive_regulation of Pth 177 0.70 127.09 27.26 99.98
49 INT724 Negative_regulation of Alb 151 0.59 93.57 29.65 99.98
50 INT36500 Negative_regulation of Gene_expression of Tf 4 0.38 1.22 1.29 99.98
51 INT57881 Binding of Tead1 2 0.25 1.63 0.7 99.98
52 INT47038 Gene_expression of SFRP1 14 0.67 9.6 0.63 99.98
53 INT107321 Regulation of Regulation of Kcne1 1 0.15 0 0.63 99.98
54 INT58170 Regulation of Kcne1 4 0.18 0 2.19 99.98
55 INT36499 Negative_regulation of Tf 6 0.38 3.02 1.85 99.98
56 INT94381 Negative_regulation of Col4a2 2 0.31 0.57 0.43 99.98
57 INT115415 Positive_regulation of Syt12 1 0.08 0 0.62 99.98
58 INT64031 Negative_regulation of Gene_expression of Il2rb 1 0.19 0 0.52 99.98
59 INT23657 Positive_regulation of APP 64 0.70 39.76 16.68 99.98
60 INT39755 Positive_regulation of Positive_regulation of CEBPZ 4 0.41 0.06 0.56 99.98
61 INT1561 Negative_regulation of Dnahc8 59 0.59 18.12 20.99 99.98
62 INT5440 Negative_regulation of Ina 85 0.58 10.52 28.98 99.96
63 INT1799 Negative_regulation of Mogat2 1 0.42 0.18 0.63 99.96
64 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02 99.92
65 INT7678 Localization of Alb 142 0.81 80.93 22.49 99.92
66 INT9748 Negative_regulation of Sysbp1 28 0.35 8.93 3.87 99.92
67 INT12063 Regulation of Ms2 1 0.23 0.09 0.77 99.92
68 INT49651 Gene_expression of Creb1 276 0.78 114.77 111.96 99.92
69 INT285 Positive_regulation of Salpa1 73 0.68 61.47 9.19 99.92
70 INT6391 Positive_regulation of Tspo 2 0.50 0.93 1.63 99.90
71 INT47615 Negative_regulation of DNASE1 9 0.58 3.62 1.74 99.90
72 INT49234 Negative_regulation of Localization of DNASE1 1 0.38 0 0.22 99.90
73 INT234 Binding of Alb 151 0.48 52.34 32.97 99.88
74 INT217612 Positive_regulation of Dep1 9 0.32 1.84 1.01 99.88
75 INT3060 Negative_regulation of Bche 94 0.59 46.75 18.51 99.88
76 INT443 Localization of POMC 1020 0.81 284.52 443.17 99.84
77 INT374 Positive_regulation of Ldha 212 0.70 107.08 47.43 99.84
78 INT81828 Positive_regulation of Kcnk3 7 0.45 1.43 1.54 99.84
79 INT22041 Negative_regulation of Gtpc 5 0.01 0.17 2.86 99.84
80 INT5597 Gene_expression of Pdyn 433 0.78 62.97 235.47 99.84
81 INT1169 Negative_regulation of Bche 322 0.59 149.22 61.27 99.84
82 INT15209 Negative_regulation of Regulation of Th 6 0.51 1.64 2.16 99.84
83 INT38153 Binding of Vps54 6 0.31 7.31 0.57 99.84
84 INT42819 Positive_regulation of Negative_regulation of Ina 4 0.40 0.07 0.92 99.84
85 INT123402 Positive_regulation of KCNK18 2 0.70 0 0.66 99.84
86 INT1223 Negative_regulation of Snai1 15 0.38 2.05 8.46 99.82
87 INT157 Positive_regulation of Localization of Prl 790 0.70 104.54 374.78 99.80
88 INT47039 Regulation of SFRP1 14 0.62 7.44 0.92 99.80
89 INT38087 Regulation of Adh1 15 0.61 4.56 4.83 99.80
90 INT3439 Localization of Abat 1017 0.78 112.39 727.06 99.78
91 INT613 Gene_expression of Alb 268 0.78 149.84 42.78 99.78
92 INT9199 Positive_regulation of CEBPZ 111 0.67 30.99 28.45 99.78
93 INT17271 Positive_regulation of CDNF 11 0.28 2.69 5.03 99.78
94 INT5660 Binding of Oprd1 477 0.48 71.86 342.06 99.78
95 INT390 Positive_regulation of Agt 170 0.70 61.47 36.08 99.76
96 INT10879 Positive_regulation of Avp 39 0.65 14.01 8.76 99.76
97 INT11300 Positive_regulation of Gene_expression of Avp 24 0.50 10.18 2.69 99.76
98 INT62570 Binding of Pth 48 0.48 26.45 4.85 99.76
99 INT103825 Regulation of Binding of Pth 1 0.27 0.63 0.45 99.76
100 INT3275 Negative_regulation of Slco1c1 28 0.37 10.93 5.15 99.76
101 INT68722 Regulation of Pomgnt1 1 0.07 0 0.27 99.76
102 INT2393 Positive_regulation of Mb 174 0.69 93.59 26.79 99.74
103 INT9483 Gene_expression of Junb 34 0.78 3.24 12.08 99.72
104 INT3154 Negative_regulation of Cyb5a 4 0.58 0.22 0.91 99.72
105 INT120215 Regulation of Gabrp 1 0.24 0 0.48 99.72
106 INT45813 Negative_regulation of Negative_regulation of Gabrg1 10 0.46 0.66 4.51 99.72
107 INT5254 Positive_regulation of Pla2g2a 22 0.68 10.42 6.37 99.70
108 INT74924 Positive_regulation of LOC100362295 3 0.36 1.39 2.4 99.70
109 INT1477 Positive_regulation of Localization of Hpcl1 1 0.41 0.08 0.25 99.70
110 INT2339 Positive_regulation of CB 30 0.29 10.68 9.12 99.68
111 INT40102 Positive_regulation of Phosphorylation of POMC 3 0.44 0.57 1.3 99.68
112 INT51703 Positive_regulation of Phosphorylation of AVP 1 0.49 0.09 0.86 99.68
113 INT5623 Positive_regulation of Nppa 174 0.70 69.96 52.33 99.68
114 INT304823 Negative_regulation of Rasa1 6 0.10 0.39 0.76 99.68
115 INT97 Negative_regulation of Adrb1 102 0.59 32.44 26.9 99.68
116 INT3301 Positive_regulation of Slc43a3 26 0.55 5.48 10.81 99.68
117 INT7779 Negative_regulation of Adra2a 47 0.58 9.45 28 99.68
118 INT5619 Positive_regulation of Gene_expression of Nppa 21 0.70 11.95 4.41 99.68
119 INT168367 Localization of Cyp2e1 2 0.71 0.6 0.72 99.66
120 INT49235 Localization of DNASE1 7 0.81 1.69 1.04 99.66
121 INT2532 Negative_regulation of Cebpz 98 0.00 53.06 28.57 99.64
122 INT58114 Localization of sc 3 0.79 0.3 1.48 99.64
123 INT32024 Positive_regulation of Positive_regulation of Snai1 2 0.25 0.32 1.7 99.64
124 INT20914 Positive_regulation of Snai1 13 0.41 3.41 7.69 99.64
125 INT65192 Positive_regulation of Localization of sc 1 0.50 0.08 0.63 99.64
126 INT1200 Negative_regulation of Ins1 274 0.58 155.17 56.14 99.64
127 INT7313 Negative_regulation of CDNF 7 0.05 2.53 2.34 99.64
128 INT73110 Gene_expression of Kcnk1 6 0.75 0.05 1.19 99.64
129 INT2531 Positive_regulation of Cebpz 166 0.00 43.08 38.86 99.62
130 INT2365 Positive_regulation of Cck 354 0.70 87.8 277.41 99.62
131 INT76529 Positive_regulation of EIF2C2 5 0.04 2.67 3.38 99.62
132 INT79710 Negative_regulation of M1 5 0.32 0.25 0.67 99.62
133 INT10681 Negative_regulation of Csn1s1 13 0.37 2.96 4.55 99.62
134 INT214 Localization of AVP 370 0.81 208.51 91.09 99.60
135 INT2909 Positive_regulation of Abat 334 0.70 62.1 256.43 99.58
136 INT56590 Positive_regulation of Atp2b4 7 0.28 2.64 1.76 99.58
137 INT41359 Negative_regulation of Atp2b4 10 0.46 3.32 1.76 99.58
138 INT24800 Negative_regulation of AMPD1 44 0.59 21.19 6.76 99.58
139 INT113002 Localization of Nmt2 1 0.60 0.23 0.31 99.58
140 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 99.56
141 INT11996 Gene_expression of Ina 34 0.67 4.8 13.82 99.56
142 INT4715 Positive_regulation of Xdh 20 0.69 6.57 2.28 99.56
143 INT11565 Gene_expression of Tf 24 0.68 5.89 4.36 99.54
144 INT4829 Positive_regulation of Localization of Abat 199 0.55 20.91 150.48 99.54
145 INT79709 Regulation of M1 13 0.24 4.8 4.9 99.54
146 INT385 Gene_expression of Agt 182 0.78 63.62 37.91 99.52
147 INT375 Positive_regulation of REN 293 0.70 152.46 47.55 99.52
148 INT57882 Negative_regulation of Kcnj5 33 0.35 13.06 12.27 99.52
149 INT27832 Positive_regulation of Ak1 5 0.46 0.96 0.77 99.52
150 INT5762 Negative_regulation of Gene_expression of Agt 18 0.57 6.09 5.84 99.52
151 INT11306 Regulation of Gene_expression of Agt 7 0.45 3.29 1.31 99.52
152 INT304822 Regulation of Negative_regulation of Rasa1 1 0.05 0 0.14 99.52
153 INT35636 Gene_expression of Sord 6 0.78 2.31 1.35 99.52
154 INT725 Negative_regulation of IgG 62 0.41 37.21 8.16 99.52
155 INT9751 Localization of Crhr1 26 0.78 10.47 15.69 99.48
156 INT16356 Regulation of NPPA 33 0.62 13.24 9.53 99.48
157 INT1472 Positive_regulation of Ins1 349 0.69 146.2 86.36 99.48
158 INT65166 Negative_regulation of PLA2G4A 7 0.57 1.55 0.96 99.42
159 INT38190 Negative_regulation of Svs4 7 0.39 1.46 3.18 99.40
160 INT1476 Localization of Hpcl1 3 0.61 0.29 0.62 99.40
161 INT71569 Protein_catabolism of Map2 4 1.00 2.8 1.92 99.40
162 INT169250 Gene_expression of Kcnk13 1 0.27 0 0.41 99.40
163 INT117024 Negative_regulation of Localization of Acot1 6 0.41 1.56 1.7 99.38
164 INT1928 Negative_regulation of Lpl 18 0.51 11.22 2.49 99.38
165 INT314 Positive_regulation of Ren 212 0.70 66.68 55.56 99.36
166 INT10796 Gene_expression of CYP2B6 131 0.77 30.14 35.27 99.36
167 INT316 Regulation of Cebpz 105 0.00 27.21 35.41 99.36
168 INT18986 Regulation of FANCA 2 0.22 1.1 0.63 99.36
169 INT74688 Regulation of Nos1 55 0.62 22.16 25.3 99.36
170 INT190390 Binding of Napb 6 0.22 2.07 2.01 99.36
171 INT77371 Regulation of Regulation of Cebpz 4 0.45 0.45 2.42 99.36
172 INT2391 Negative_regulation of PTGS1 501 0.59 207.62 205.6 99.36
173 INT6669 Negative_regulation of Positive_regulation of Fos 98 0.59 23.5 56.82 99.34
174 INT11303 Gene_expression of Avp 116 0.78 39.23 23.88 99.34
175 INT218 Positive_regulation of Th 245 0.70 40.5 120.1 99.34
176 INT158 Localization of Prl 2431 0.81 378.96 952.2 99.32
177 INT71189 Gene_expression of Cyp1a2 24 0.78 11.39 11.12 99.32
178 INT64032 Gene_expression of Il2rb 2 0.30 0 0.52 99.30
179 INT5622 Gene_expression of Nppa 101 0.78 49.46 25.31 99.30
180 INT1308 Localization of Pomc 457 0.81 66.83 217.5 99.28
181 INT9516 Negative_regulation of Gabrg1 149 0.53 27.83 91.02 99.28
182 INT93087 Negative_regulation of Rho 1 0.59 0 0.2 99.26
183 INT3948 Regulation of Cck 291 0.62 58.07 255.88 99.24
184 INT64558 Negative_regulation of Nos1 88 0.58 26.76 36.78 99.24
185 INT127425 Positive_regulation of Mef2a 5 0.67 0 2.25 99.20
186 INT45437 Localization of Acot1 84 0.79 17.37 22.18 99.20
187 INT49538 Binding of Gria1 22 0.47 2.66 13.35 99.20
188 INT10166 Localization of Tnf 237 0.81 153.95 88.64 99.20
189 INT3892 Positive_regulation of XDH 8 0.67 8.57 1.5 99.20
190 INT109037 Regulation of Tens1 4 0.33 1.93 7.07 99.20
191 INT292 Localization of Penk 876 0.81 88.44 669.14 99.18
192 INT5228 Positive_regulation of Fos 934 0.70 209.8 503.87 99.16
193 INT64824 Negative_regulation of sar 11 0.42 18.7 5.6 99.16
194 INT5817 Localization of Melm1 23 0.68 2.05 18.01 99.12
195 INT115227 Regulation of Localization of Acot1 12 0.60 0.15 3.51 99.12
196 INT2695 Regulation of DBH 5 0.45 1.09 2.48 99.10
197 INT287 Localization of Cck 518 0.81 86.84 364.04 99.08
198 INT11764 Positive_regulation of ENG 78 0.61 27.65 33.69 99.08
199 INT87890 Regulation of Gene_expression of Pnoc 8 0.44 2.45 7.66 99.08
200 INT48767 Negative_regulation of NOS1 312 0.59 154.25 90.32 99.06
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