P:Hyperalgesia

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pChart

Pain Term
Category Pain type
Synonyms None
Pain Specific Yes
Documents 5749
Hot Single Events 200
Hot Interactions 200

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Hyperalgesia. They are ordered first by their pain relevance and then by number of times they were reported for Hyperalgesia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT356289 Binding of Egfr and Egf 1 0.13 3.02 2.52 100.00
2 INT96652 F2rl1 Positive_regulation of Tac1 1 0.47 2.62 2.25 100.00
3 INT140532 Gtf3a Positive_regulation of DYT10 1 0.12 1.83 1.34 100.00
4 INT140531 Ngf Positive_regulation of DYT10 1 0.72 1.83 1.34 100.00
5 INT128604 Casp1 Positive_regulation of Gene_expression of Fos 1 0.10 0.55 0.59 100.00
6 INT128606 Pomc Positive_regulation of Gene_expression of Fos 1 0.02 0.55 0.59 100.00
7 INT150889 Il1a Regulation of Il10 1 0.22 3.49 2.95 100.00
8 INT150886 Il1a Regulation of Il1b 1 0.02 3.46 2.93 100.00
9 INT150888 Il1a Regulation of Il6 1 0.10 3.47 2.93 100.00
10 INT147660 Positive_regulation of Prkce Positive_regulation of TRPV1 1 0.04 0.69 1.12 100.00
11 INT121730 Pik3cb Regulation of Trpv1 1 0.58 0.54 1.09 100.00
12 INT156545 Il13 Positive_regulation of Gene_expression of Il12a 1 0.27 1.56 1.13 100.00
13 INT96241 Il13 Negative_regulation of Tnf 1 0.08 0.6 0.59 100.00
14 INT96240 Il13 Negative_regulation of Il1b 1 0.17 0.6 0.59 100.00
15 INT283932 Positive_regulation of Mapk14 Regulation of Gene_expression of Trpv1 1 0.14 1.28 0.99 100.00
16 INT120313 Gnrhr Negative_regulation of Mmp2 1 0.03 0.85 1.07 100.00
17 INT120315 Gnrhr Negative_regulation of Positive_regulation of Ngf 1 0.11 0.85 1.07 100.00
18 INT120318 Gnrhr Negative_regulation of Ngf 1 0.11 0.85 1.07 100.00
19 INT51224 Gal Negative_regulation of Localization of Oxt 1 0.27 0.39 0.51 100.00
20 INT150885 Il6 Regulation of Il10 1 0.22 1.74 1.47 100.00
21 INT150887 Il1b Regulation of Il10 1 0.04 1.74 1.47 100.00
22 INT356284 Ptger2 Positive_regulation of Prkaca 1 0.00 0.39 0.37 100.00
23 INT121725 Binding of Trpv1 and Pik3cb 1 0.35 0.62 1.15 100.00
24 INT109016 Negative_regulation of Prkg1 Negative_regulation of Positive_regulation of PRKG1 1 0.06 0.28 0.26 100.00
25 INT128700 BBS9 Negative_regulation of Il12a 1 0.47 0.76 1.03 99.96
26 INT160985 Urb1 Negative_regulation of Negative_regulation of Faah 1 0.41 1.36 0.74 99.96
27 INT147659 Prkce Positive_regulation of TRPV1 1 0.04 1.42 2.43 99.90
28 INT131819 Binding of Cpox and Nfkb1 1 0.15 0.44 0.46 99.90
29 INT143941 Il1f5 Negative_regulation of Gene_expression of Fos 1 0.00 1.03 1.11 99.80
30 INT110518 Tnf Positive_regulation of Prkce 1 0.26 1.43 0.78 99.80
31 INT106558 Binding of Ntrk2 and Ntrk3 3 0.52 2.51 2.28 99.78
32 INT141911 Arih2 Regulation of Positive_regulation of Cpox 1 0.01 1.19 0.76 99.72
33 INT141910 Arih2 Regulation of Cpox 1 0.01 1.19 0.76 99.72
34 INT112514 Binding of Prkaca and Trib3 1 0.03 1.18 1.9 99.66
35 INT112515 Binding of Ephb1 and Trib3 1 0.06 0.41 0.65 99.66
36 INT112516 Binding of Prkce and Trib3 1 0.01 0.4 0.64 99.66
37 INT90121 Nos1 Regulation of Fos 1 0.27 0.25 0.49 99.64
38 INT106676 Binding of Trpv1 and Phax 18 0.34 4.19 12.36 99.62
39 INT142437 Urb1 Negative_regulation of Faah 3 0.41 2.12 1.66 99.60
40 INT140024 Tnf Positive_regulation of Gene_expression of Il1b 2 0.49 2.75 2.61 99.56
41 INT106560 Binding of Ntf3 and Ntrk2 3 0.14 2.47 2.84 99.52
42 INT116777 Psma5 Positive_regulation of Binding of Fn1 1 0.01 1.24 1.06 99.48
43 INT262578 Prkaca Positive_regulation of Localization of Calca 1 0.03 0.71 0.75 99.48
44 INT112517 Binding of Ephb1 and Prkaca 3 0.18 0.58 1.85 99.46
45 INT112513 Binding of Prkaca and Prkce 1 0.04 0.4 0.64 99.46
46 INT228457 Negative_regulation of Ins1 Positive_regulation of Gene_expression of Trpv1 1 0.05 1.01 0.21 99.44
47 INT90131 NOS1 Regulation of Fos 1 0.00 0.25 0.49 99.40
48 INT139987 Oprm1 Positive_regulation of Localization of Oprl1 1 0.16 0.17 1.35 99.40
49 INT77791 fut10 Regulation of Regulation of Tnfrsf1a 1 0.02 0.85 0.36 99.34
50 INT86413 Pomc Regulation of Cor 1 0.01 0.17 0.3 99.32
51 INT81657 Binding of CPOX and PTGS1 5 0.15 1.9 2.37 99.28
52 INT124088 Rab38 Negative_regulation of Mapk14 1 0.00 0.89 0.42 99.24
53 INT90120 Jun Positive_regulation of Gene_expression of Nos1 1 0.38 0.39 0.76 99.20
54 INT90117 Jun Regulation of Gene_expression of Nos1 1 0.21 0.39 0.76 99.20
55 INT90125 Nfkb1 Regulation of Gene_expression of Nos1 1 0.17 0.39 0.76 99.20
56 INT90116 Nfkb1 Positive_regulation of Gene_expression of Nos1 1 0.32 0.39 0.76 99.20
57 INT65724 Binding of Pnoc and Oprl1 8 0.33 2.94 8.82 99.20
58 INT140966 NFKB1 Positive_regulation of Positive_regulation of CPOX 1 0.08 0.66 0.8 99.20
59 INT125950 Syt17 Regulation of Trpv1 1 0.11 0.43 1.28 99.18
60 INT276865 Regulation of Trpv1 Regulation of Gene_expression of Gpr65 1 0.25 0.62 0.76 99.08
61 INT308172 Rvm Positive_regulation of Phosphorylation of GRIN1 1 0.50 0.68 1.14 99.04
62 INT262571 Phosphorylation of Trpv1 Positive_regulation of Localization of Calca 1 0.17 0.71 0.7 98.96
63 INT296484 Binding of Gria2 and GRIP1 1 0.04 4.52 4.59 98.92
64 INT274948 Binding of Dh and Ltp 1 0.11 0.55 1.23 98.88
65 INT348380 Binding of Fdps and Lpar5 1 0.07 1.45 1.25 98.84
66 INT348396 Binding of LPAR5 and Fdps 1 0.07 0.81 0.69 98.84
67 INT126020 Binding of fc and Tnf 1 0.22 1.61 0.43 98.66
68 INT126019 Binding of Ltbr and Tnf 1 0.18 1.61 0.43 98.66
69 INT126018 Binding of Lifr and Tnf 1 0.06 1.61 0.43 98.66
70 INT151826 Tnf Positive_regulation of TNF 1 0.04 3.38 2.51 98.64
71 INT78714 Ntrk1 Positive_regulation of Ngf 2 0.50 0.63 0.78 98.64
72 INT338058 Par2 Positive_regulation of Positive_regulation of Trpv1 1 0.17 0.37 0.2 98.60
73 INT152113 Binding of NTSR1 and Ngf 3 0.33 2.09 2.62 98.44
74 INT143939 Il1b Regulation of Gene_expression of Fos 1 0.10 0.44 0.49 98.44
75 INT24967 Olr567 Regulation of Localization of Syt17 1 0.11 0.62 0.71 98.44
76 INT222243 Negative_regulation of Binding of Trpv1 and Ccr5 1 0.21 0.57 0.86 98.40
77 INT222244 Binding of Trpv1 and Ccr5 1 0.19 0.57 0.86 98.40
78 INT154255 Tnf Positive_regulation of IL1B 1 0.54 0.94 0.97 98.38
79 INT154254 Tnf Positive_regulation of Il6 1 0.36 0.94 0.97 98.38
80 INT165724 Bdkrb1 Positive_regulation of Adora1 1 0.24 1.65 0.43 98.28
81 INT256299 Binding of Efnb1 and Ephb1 1 0.02 1.22 1.42 98.24
82 INT249497 Efnb2 Positive_regulation of Phosphorylation of Grin2b 1 0.02 0.51 0.54 98.24
83 INT51225 Gal Regulation of Localization of Oxt 1 0.32 0.35 0.29 98.02
84 INT123387 Binding of Camk2a and Gria2 1 0.13 0.32 1.14 98.00
85 INT140890 Il10 Regulation of Il6 1 0.35 0.73 0.58 97.96
86 INT115272 Neu1 Positive_regulation of Coq10a 1 0.43 0.41 1.35 97.96
87 INT153534 Binding of Ephb1 and NMS 1 0.29 1.13 0.5 97.96
88 INT314214 Mapk14 Positive_regulation of Ngf 1 0.43 1.97 1.56 97.64
89 INT121727 Pik3cb Positive_regulation of Ephb1 1 0.49 0.6 1.06 97.64
90 INT166301 Adrbk1 Positive_regulation of Localization of Trpv1 1 0.45 1.17 1.2 97.60
91 INT180813 Ngf Positive_regulation of Sorbs1 1 0.04 2.09 3.79 97.52
92 INT145775 Ngf Positive_regulation of Trpv1 11 0.72 7.71 11.25 97.52
93 INT261845 NGF Positive_regulation of Trpa1 1 0.04 0.73 0.71 97.52
94 INT96242 Il13 Negative_regulation of Gene_expression of Il1b 1 0.15 0.67 0.59 97.40
95 INT115271 Neu1 Positive_regulation of Coq10a 1 0.01 0.41 1.35 97.36
96 INT146412 Tnf Positive_regulation of Gene_expression of Trpv1 2 0.66 5.22 3.22 97.32
97 INT151825 Tnf Positive_regulation of Mapk14 1 0.22 1.72 1.09 97.32
98 INT127876 ACE Positive_regulation of Protein_catabolism of CALCA 1 0.28 0.63 0.75 97.12
99 INT128996 Ccl2 Positive_regulation of Localization of Calca 1 0.68 1.43 2 97.12
100 INT109842 Prkce Positive_regulation of Localization of Trpv1 1 0.13 1.31 0.91 97.08
101 INT190130 Binding of CPOX and MRXS5 1 0.00 1.4 1.23 97.04
102 INT256298 Binding of Creb1 and Ephb1 1 0.16 1.27 1.22 96.96
103 INT256294 Binding of Grin2b and Ephb1 1 0.28 1.11 1.08 96.96
104 INT93690 Bdnf Regulation of Localization of Tacr1 1 0.10 0.28 0.61 96.96
105 INT90119 Ntrk2 Regulation of Gene_expression of Nfkb1 1 0.01 0.27 0.6 96.92
106 INT143938 Il1rn Negative_regulation of Il1b 1 0.04 0.52 0.57 96.88
107 INT143940 Il1rn Negative_regulation of Il1f5 1 0.00 0.51 0.57 96.88
108 INT147653 TACR1 Positive_regulation of TRPV1 1 0.02 0.72 1.29 96.88
109 INT122269 Src Negative_regulation of Positive_regulation of Grin2b 1 0.27 0.44 0.92 96.88
110 INT308167 Binding of Eln and Tnfrsf1b 1 0.01 0.94 0.71 96.88
111 INT149386 Binding of Lyn and TRPV4 1 0.40 1.14 0.91 96.76
112 INT128998 Cxcl1 Positive_regulation of Localization of Calca 1 0.66 2.96 4.15 96.76
113 INT256297 Binding of Creb1 and Insrr 1 0.00 1.22 1.19 96.72
114 INT256293 Binding of Grin2b and Insrr 1 0.01 1.06 1.05 96.72
115 INT90123 Jun Positive_regulation of Gene_expression of Fos 1 0.47 0.39 0.76 96.52
116 INT90122 Nfkb1 Positive_regulation of Gene_expression of Fos 1 0.39 0.39 0.75 96.52
117 INT121843 HLA-DRB5 Negative_regulation of Accn4 1 0.00 0.54 0.73 96.52
118 INT155406 Binding of Adrb2 and Ngf 1 0.05 0.39 0.53 96.48
119 INT284785 Gch1 Regulation of Bh4p 1 0.00 1.48 1.54 96.40
120 INT128044 Bdnf Positive_regulation of Ephb1 2 0.31 1.89 2.57 96.20
121 INT118812 Cck Positive_regulation of Rvm 1 0.21 0.65 1.46 96.20
122 INT169802 Negative_regulation of Adrbk1 Positive_regulation of Positive_regulation of Rapgef3 1 0.44 0.75 1.19 96.16
123 INT90118 Jun Regulation of Gene_expression of Nfkb1 1 0.18 0.39 0.76 96.16
124 INT212658 KCNA1 Positive_regulation of Cort 1 0.00 2.58 3.36 96.08
125 INT122266 Src Negative_regulation of Grin2b 1 0.27 0.43 0.91 96.00
126 INT256295 Binding of Creb1 and Grin2b 1 0.11 1.21 1.19 95.92
127 INT84369 Ngf Positive_regulation of KNG1 1 0.04 0.29 0.89 95.84
128 INT195927 Binding of Prkaca and Trpv1 1 0.07 0.28 0.92 95.72
129 INT113451 Ngf Regulation of Gene_expression of ASIC3 1 0.07 1.35 2.18 95.64
130 INT308173 Binding of DRG1 and Tnfrsf1b 1 0.01 1.64 1.1 95.64
131 INT90115 Ntrk2 Regulation of Jun 1 0.01 0.27 0.57 95.44
132 INT96245 Negative_regulation of Tnf Positive_regulation of KNG1 1 0.01 0.59 0.45 95.40
133 INT153994 Regulation of Prkaca Regulation of TRPV1 1 0.02 0.46 0.44 95.40
134 INT153995 Regulation of Myoz1 Regulation of TRPV1 1 0.00 0.46 0.44 95.40
135 INT153993 Myoz1 Regulation of TRPV1 1 0.00 0.46 0.44 95.40
136 INT104855 Prkaca Regulation of TRPV1 3 0.06 1.52 1.92 95.40
137 INT252633 Binding of TNF and Tnfrsf1b 4 0.05 3.66 1.54 95.36
138 INT220061 Binding of TRPV1 and TRPA1 1 0.15 1.7 2.69 95.32
139 INT66535 Binding of Pnoc and Oprl1 43 0.54 5.93 32.4 95.12
140 INT322131 Binding of Prkcg and Trpv4 1 0.04 0.75 0.46 95.12
141 INT322129 Binding of Prkcg and Ca2 1 0.00 0.57 0.33 95.12
142 INT69229 Ngf Positive_regulation of Gene_expression of Bdnf 6 0.76 8.19 6.66 95.04
143 INT96246 Tnf Positive_regulation of KNG1 1 0.01 0.59 0.45 95.00
144 INT135582 Prok2 Positive_regulation of Localization of Prkce 1 0.06 1.02 1.87 94.96
145 INT113452 Ngf Positive_regulation of Gene_expression of ASIC3 1 0.19 1.34 2.08 94.64
146 INT348381 Fdps Positive_regulation of Lpar5 1 0.07 0.75 0.64 94.64
147 INT348399 Fdps Positive_regulation of LPAR5 1 0.08 0.75 0.64 94.64
148 INT75370 Positive_regulation of Binding of Hrh1 and RGD735065 1 0.00 0.56 1.41 94.56
149 INT122286 Prkaca Negative_regulation of Negative_regulation of Calca 1 0.12 0.54 1.63 94.40
150 INT162329 Tmc1 Negative_regulation of Gene_expression of Ptges2 1 0.03 0.58 0.47 94.40
151 INT276864 Positive_regulation of Gpr65 Positive_regulation of Prkaca 1 0.16 0.74 0.97 94.32
152 INT312813 Binding of F2rl1 and Tpsab1 1 0.01 0.26 0.46 94.32
153 INT120319 Ghrh Regulation of Ngf 1 0.25 1.89 2.11 94.08
154 INT120317 Ghrh Regulation of Positive_regulation of Ngf 1 0.25 0.95 1.06 94.08
155 INT120311 Ghrh Regulation of Gene_expression of Ngf 1 0.25 0.95 1.06 94.08
156 INT120316 Ghrh Regulation of Il6 1 0.11 0.95 1.05 94.08
157 INT120310 Ghrh Regulation of Positive_regulation of Il6 1 0.18 0.95 1.05 94.08
158 INT120312 Ghrh Regulation of Tnf 1 0.26 0.95 1.05 94.08
159 INT120314 Ghrh Regulation of Positive_regulation of Tnf 1 0.43 0.95 1.05 94.08
160 INT292531 Il10 Negative_regulation of Positive_regulation of Mapk14 1 0.15 1.13 1.06 94.04
161 INT314197 Mapk14 Positive_regulation of Positive_regulation of Tnf 1 0.48 1.16 0.61 94.04
162 INT75371 Binding of Hrh1 and RGD735065 1 0.00 0.55 1.4 94.00
163 INT111555 Negative_regulation of Npr1 Negative_regulation of Positive_regulation of Creb1 1 0.02 0.58 0.66 93.92
164 INT182564 Binding of Ptger2 and Trpv1 1 0.18 1.77 2.67 93.92
165 INT249494 Binding of Ephb1 and Efnb1 1 0.01 1.34 1.4 93.92
166 INT249537 Binding of Ephb1 and Efnb1 Positive_regulation of Phosphorylation of Grin2b 1 0.01 0.68 0.71 93.92
167 INT162319 Positive_regulation of F2rl1 Positive_regulation of Il1b 1 0.46 1.6 1.04 93.76
168 INT169801 Binding of Adrbk1 and Rapgef3 1 0.34 1.04 1.43 93.68
169 INT334351 Bdnf Regulation of Positive_regulation of Ephb1 1 0.18 1.27 1.2 93.64
170 INT180809 Ngf Positive_regulation of Positive_regulation of Sorbs1 1 0.03 0.84 1.4 93.48
171 INT121457 KNG1 Positive_regulation of Trpv1 1 0.16 0.91 1.33 93.44
172 INT219279 Ctss Positive_regulation of Gene_expression of Fam64a 1 0.06 1.39 0.96 93.44
173 INT219273 Fam64a Positive_regulation of Gene_expression of Ctss 1 0.06 1.39 0.96 93.44
174 INT121458 KNG1 Positive_regulation of Localization of Trpv1 1 0.16 0.43 0.69 93.44
175 INT291011 Pomc Regulation of Gene_expression of ENG 1 0.08 0.86 0.91 93.20
176 INT128603 Il1b Positive_regulation of Gene_expression of Fos 1 0.50 0.59 0.58 93.08
177 INT122268 Binding of Grin2b and Grm5 1 0.40 0.52 1.1 93.04
178 INT128997 Cxcl1 Positive_regulation of Localization of Ccl2 1 0.72 1.54 2.16 93.04
179 INT296458 Binding of Gria2 and Pick1 3 0.24 1.86 1.07 92.96
180 INT296475 Binding of Pick1 and Myo18a 2 0.01 1.63 0.57 92.96
181 INT296476 Binding of Pick1 and Rbm39 1 0.00 0.57 0.37 92.96
182 INT168281 Tlr4 Positive_regulation of Phosphorylation of Mapk4 1 0.06 1.05 0.89 92.92
183 INT315284 PRKG1 Positive_regulation of Nos1 1 0.33 0.85 1.56 92.88
184 INT85541 Ngf Positive_regulation of Gene_expression of Calca 2 0.55 1.84 3.71 92.80
185 INT69886 Ngf Positive_regulation of Calca 8 0.76 2.98 12.77 92.80
186 INT169800 Negative_regulation of Adrbk1 Positive_regulation of Positive_regulation of Mapk1 1 0.39 1.04 1.45 92.64
187 INT180802 Gdnf Positive_regulation of Sorbs1 1 0.02 0.98 1.34 92.60
188 INT122779 Ngf Positive_regulation of Gene_expression of Trpv1 8 0.74 4.31 6.1 92.40
189 INT180808 Ngf Positive_regulation of Gene_expression of Sorbs1 1 0.03 0.84 1.4 92.40
190 INT261831 Mapk1 Negative_regulation of Hspg2 1 0.00 1.26 1.42 92.36
191 INT107028 KNG1 Regulation of Des 1 0.01 1.7 0.76 92.28
192 INT18026 Binding of Oprd1 and Oprm1 4 0.40 0.83 3.53 92.28
193 INT182551 Ptgir Negative_regulation of Trpv1 1 0.19 0.7 0.51 92.24
194 INT190771 Gene_expression of Il4 Negative_regulation of Gene_expression of Mapk14 1 0.15 1.14 1.13 91.96
195 INT190770 Il4 Negative_regulation of Gene_expression of Mapk14 1 0.20 1.14 1.13 91.96
196 INT182550 Ptger1 Negative_regulation of Trpv1 1 0.35 0.73 1.12 91.96
197 INT296460 Binding of Gria2 and Myo18a 1 0.01 1.49 1.06 91.80
198 INT296444 Binding of Rbm39 and Myo18a 1 0.00 0.56 0.36 91.80
199 INT77792 fut10 Negative_regulation of Positive_regulation of Tnfrsf1a 1 0.04 0.82 0.32 91.76
200 INT228681 Fkbp4 Negative_regulation of Trib3 1 0.00 0.57 1.2 91.32

Single Events

The table below shows the top 200 pain related interactions that have been reported for Hyperalgesia. They are ordered first by their pain relevance and then by number of times they were reported in Hyperalgesia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT11377 Positive_regulation of Ngf 331 0.70 206.5 238 100.00
2 INT5202 Positive_regulation of Gene_expression of Fos 1163 0.70 319.28 684 100.00
3 INT87687 Positive_regulation of Trpv1 409 0.70 210.24 257.59 100.00
4 INT10272 Gene_expression of Il1b 194 0.78 121.02 103.03 100.00
5 INT6056 Negative_regulation of Gene_expression of Fos 601 0.59 193.05 386.84 100.00
6 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 100.00
7 INT24326 Gene_expression of Ngf 346 0.78 218.67 184.71 100.00
8 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08 100.00
9 INT64202 Positive_regulation of Trpv1 643 0.70 249.66 397.42 100.00
10 INT18357 Gene_expression of TRPV1 825 0.78 307.11 382.81 100.00
11 INT16254 Positive_regulation of Gene_expression of Ngf 144 0.70 80.61 82.08 100.00
12 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 100.00
13 INT10273 Positive_regulation of Gene_expression of Il1b 47 0.68 31.15 26.21 100.00
14 INT64261 Negative_regulation of Positive_regulation of Ngf 21 0.59 16.28 19.78 100.00
15 INT47243 Gene_expression of Prkcg 195 0.78 58.05 108.44 100.00
16 INT10706 Regulation of Il6 150 0.62 93.23 62.34 100.00
17 INT19078 Binding of Ngf 78 0.48 31.03 44.33 100.00
18 INT5307 Regulation of Tnf 87 0.62 78.71 43.4 100.00
19 INT7134 Localization of KNG1 127 0.79 65.73 67.97 100.00
20 INT12001 Regulation of Ngf 97 0.62 54.64 76.25 100.00
21 INT12501 Positive_regulation of Adarb1 166 0.58 36.94 118.92 100.00
22 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 100.00
23 INT124881 Binding of Trpv4 35 0.47 7.71 6.24 100.00
24 INT5590 Negative_regulation of Fos 144 0.59 40.94 81.98 100.00
25 INT27954 Positive_regulation of Gene_expression of Ngf 87 0.70 57.91 51.96 100.00
26 INT6864 Positive_regulation of Gene_expression of Gfap 110 0.70 59.01 47.07 100.00
27 INT48891 Positive_regulation of Il10 143 0.70 101.42 56.72 100.00
28 INT11011 Positive_regulation of Phosphorylation of Creb1 190 0.70 49.25 112.01 100.00
29 INT3076 Regulation of KNG1 52 0.60 20.39 27.89 100.00
30 INT11855 Positive_regulation of Gene_expression of Il1rl1 19 0.69 12.22 14.57 100.00
31 INT11013 Negative_regulation of Phosphorylation of Creb1 55 0.59 18.74 34.66 100.00
32 INT5378 Regulation of Gene_expression of Fos 47 0.60 14.47 26.41 100.00
33 INT1160 Positive_regulation of Rbm39 122 0.57 28.19 90.28 100.00
34 INT19527 Negative_regulation of Gene_expression of Il1a 26 0.51 15.4 11.58 100.00
35 INT5948 Regulation of Il1b 44 0.60 22.8 25.4 100.00
36 INT53948 Regulation of Gene_expression of Cpox 40 0.51 20.97 13.87 100.00
37 INT170646 Negative_regulation of Fig4 213 0.37 81.29 46.92 100.00
38 INT2909 Positive_regulation of Abat 334 0.70 62.1 256.43 100.00
39 INT87432 Regulation of Gene_expression of Il1rl1 6 0.58 4.5 6.62 100.00
40 INT83602 Positive_regulation of Gene_expression of TRPV1 114 0.70 51.19 56.35 100.00
41 INT60758 Gene_expression of Prkce 8 0.20 4.12 4.59 100.00
42 INT68686 Gene_expression of Olr1869 5 0.39 2.3 3.21 100.00
43 INT3950 Gene_expression of Ptger2 293 0.77 122.28 62.42 100.00
44 INT65772 Positive_regulation of Positive_regulation of Bdkrb1 6 0.49 8.34 6.54 100.00
45 INT68744 Localization of Cxcl1 18 0.80 8.65 8.6 100.00
46 INT52692 Gene_expression of Ptgs2 160 0.78 85.06 55.73 100.00
47 INT177581 Regulation of Fig4 113 0.41 39.26 27.75 100.00
48 INT6867 Positive_regulation of Gene_expression of GFAP 22 0.67 13.46 9.75 100.00
49 INT2828 Positive_regulation of Ptger3 26 0.68 8.01 9.63 100.00
50 INT9233 Negative_regulation of Gene_expression of IL1B 114 0.59 56.99 41.82 100.00
51 INT48954 Positive_regulation of Localization of Il1b 13 0.53 8.16 6.44 100.00
52 INT112174 Gene_expression of Trpv4 47 0.78 26.26 20.09 100.00
53 INT11894 Negative_regulation of Gene_expression of Ptger2 47 0.55 16.95 11.59 100.00
54 INT244386 Positive_regulation of Gene_expression of Slc12a2 10 0.58 18.39 4.5 100.00
55 INT89805 Gene_expression of Prkaca 45 0.77 11.03 20.77 100.00
56 INT3030 Gene_expression of Adra2a 37 0.68 5.58 19.76 100.00
57 INT125411 Negative_regulation of Phosphorylation of Mapk14 31 0.57 18.55 19.98 100.00
58 INT38971 Positive_regulation of Gene_expression of Gtf3a 27 0.60 18.25 7.77 100.00
59 INT52801 Regulation of Gene_expression of Tnf 55 0.62 48.74 26.59 100.00
60 INT65907 Negative_regulation of Gene_expression of Ngf 36 0.59 19.5 20.03 100.00
61 INT7553 Negative_regulation of Pih1d2 1 0.15 1.67 2.68 100.00
62 INT62254 Negative_regulation of FLII 20 0.48 4.11 9.44 100.00
63 INT7506 Negative_regulation of Ltp 267 0.46 91.01 176.8 100.00
64 INT35029 Positive_regulation of Gene_expression of Ptger2 66 0.43 26.37 13.99 100.00
65 INT13823 Gene_expression of Egf 97 0.78 39.99 12.99 100.00
66 INT48979 Regulation of Gene_expression of FOS 52 0.61 14.4 25.95 100.00
67 INT48907 Positive_regulation of Gene_expression of Oprm1 53 0.69 8.55 33.52 100.00
68 INT49993 Positive_regulation of Gene_expression of Il6 149 0.70 88.07 53.78 100.00
69 INT22066 Gene_expression of Phax 40 0.78 22.51 25.91 100.00
70 INT55578 Regulation of Gene_expression of Il1b 7 0.62 4.74 5.55 100.00
71 INT63769 Regulation of Ngf 44 0.62 21.82 25.84 100.00
72 INT67641 Negative_regulation of Gene_expression of Tlr4 90 0.58 46 14.6 100.00
73 INT65926 Positive_regulation of Gene_expression of Egf 26 0.70 12.91 4.18 100.00
74 INT73721 Negative_regulation of Gene_expression of Egf 5 0.43 2.28 1.8 100.00
75 INT6726 Positive_regulation of Edn1 118 0.70 65.96 24.07 100.00
76 INT13276 Regulation of Ltp 107 0.53 30.78 69.13 100.00
77 INT174844 Binding of Fig4 81 0.41 18.03 12.87 100.00
78 INT70848 Gene_expression of Casp1 24 0.77 10.97 8.52 100.00
79 INT102865 Positive_regulation of Positive_regulation of Prkca 25 0.69 8.34 9.9 100.00
80 INT1414 Regulation of Oprl1 169 0.62 32.05 139.99 100.00
81 INT82284 Negative_regulation of Gene_expression of Arc 10 0.41 4.26 2.58 100.00
82 INT10536 Gene_expression of Trib3 67 0.66 27.08 21.58 100.00
83 INT72612 Negative_regulation of Regulation of Pdyn 2 0.38 0.77 2.3 100.00
84 INT8532 Regulation of Transcription of PDYN 10 0.44 4.97 6.95 100.00
85 INT139130 Positive_regulation of Gene_expression of Slc12a5 8 0.51 4.43 4.33 100.00
86 INT76426 Positive_regulation of Negative_regulation of Cpox 18 0.35 6.84 9.95 100.00
87 INT128185 Gene_expression of Prkce 4 0.69 1.39 2.23 100.00
88 INT133441 Negative_regulation of Positive_regulation of Rvm 2 0.28 3.01 3.51 100.00
89 INT62253 Regulation of Gene_expression of FLII 3 0.60 0.98 1.73 100.00
90 INT55255 Positive_regulation of Localization of Il6 48 0.69 24.88 12.76 100.00
91 INT46833 Positive_regulation of SGSM3 56 0.67 24.49 30.31 100.00
92 INT241566 Negative_regulation of Negative_regulation of Calca 1 0.03 0.72 1.63 100.00
93 INT74557 Negative_regulation of Binding of Cnrip1 1 0.34 0.89 1.35 100.00
94 INT238709 Binding of PCBD1 1 0.34 2.37 1.41 100.00
95 INT281645 Regulation of Gene_expression of Phax 3 0.08 2.51 2.44 100.00
96 INT49532 Regulation of Gene_expression of Il6 43 0.61 25.8 14.99 100.00
97 INT4940 Negative_regulation of Localization of Tacr1 8 0.37 4.29 8.25 100.00
98 INT99069 Positive_regulation of Gene_expression of Mapk14 42 0.53 29.84 23.16 100.00
99 INT59245 Localization of Pla2g1b 10 0.75 4.72 2.76 100.00
100 INT75521 Positive_regulation of Positive_regulation of SGSM3 13 0.67 7.99 13.54 100.00
101 INT129496 Negative_regulation of Gene_expression of P2rx6 3 0.56 0.63 0.39 100.00
102 INT36726 Regulation of Gene_expression of Ltp 14 0.46 4.81 7.05 100.00
103 INT326657 Regulation of Binding of Ltp 1 0.09 2.26 1.36 100.00
104 INT1682 Negative_regulation of Rem1 28 0.37 7.38 8.4 100.00
105 INT91013 Binding of IFNAR1 9 0.46 8.7 2.74 100.00
106 INT10514 Negative_regulation of Gene_expression of Plat 8 0.47 6.22 2.24 100.00
107 INT47848 Negative_regulation of Positive_regulation of FOS 14 0.57 3.78 7.63 100.00
108 INT17333 Positive_regulation of Positive_regulation of FOS 17 0.67 6.06 8.4 100.00
109 INT71374 Positive_regulation of Gene_expression of Il12a 5 0.22 7.49 3.8 100.00
110 INT5854 Regulation of Gene_expression of Penk 22 0.61 6.91 10.03 100.00
111 INT35712 Regulation of Sdcbp 19 0.23 5.3 6.58 100.00
112 INT8529 Regulation of Transcription of Penk 8 0.39 1.26 5.89 100.00
113 INT76860 Gene_expression of HSPG2 32 0.65 37.14 9.06 100.00
114 INT15339 Regulation of Phax 8 0.45 4.34 6.49 100.00
115 INT75250 Negative_regulation of Positive_regulation of SGSM3 5 0.57 2.47 5.24 100.00
116 INT77429 Negative_regulation of Negative_regulation of CPOX 9 0.34 5.09 4.64 100.00
117 INT65226 Regulation of NARG2 3 0.36 1.6 1.99 100.00
118 INT24671 Binding of FGF2 14 0.35 8.73 1.43 100.00
119 INT287730 Positive_regulation of Gene_expression of Tpnr1 1 0.01 1.43 1.08 100.00
120 INT50409 Regulation of Localization of Fos 3 0.44 0.2 1.07 100.00
121 INT95879 Regulation of Gene_expression of St13 2 0.33 1.02 0.57 100.00
122 INT128187 Gene_expression of RAPGEF3 1 0.65 0.53 0.38 100.00
123 INT5680 Gene_expression of Ngf 530 0.78 264.29 310.56 99.98
124 INT10274 Positive_regulation of Il1b 123 0.70 79.76 73.56 99.98
125 INT118336 Positive_regulation of LOC682801 5 0.32 3.17 3.08 99.98
126 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58 99.98
127 INT47876 Binding of Pnoc 20 0.47 4.99 20.01 99.98
128 INT55670 Negative_regulation of Gene_expression of Tnf 83 0.59 57.16 46.33 99.98
129 INT25503 Gene_expression of C5AR1 22 0.75 21.88 4.16 99.98
130 INT33218 Gene_expression of Csrp3 1 0.24 0.84 0.94 99.98
131 INT128745 Positive_regulation of Positive_regulation of Pik3cb 4 0.56 0.95 2.24 99.98
132 INT95785 Positive_regulation of Positive_regulation of Grm1 6 0.49 3.59 3.3 99.98
133 INT79821 Negative_regulation of Binding of Pnoc 2 0.29 0.44 1.93 99.98
134 INT6067 Positive_regulation of Positive_regulation of Oprd1 37 0.69 6.56 36.58 99.98
135 INT10513 Gene_expression of Plat 44 0.76 19.49 7.17 99.98
136 INT105864 Binding of PRKG1 2 0.36 0.42 0.83 99.98
137 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84 99.96
138 INT18992 Negative_regulation of Pdpk1 53 0.42 19.02 40.95 99.96
139 INT6665 Gene_expression of FOS 520 0.77 165.31 217.66 99.96
140 INT16260 Gene_expression of Bdnf 671 0.78 283.44 339.1 99.96
141 INT62374 Gene_expression of NGF 158 0.78 77.87 76.45 99.96
142 INT52800 Negative_regulation of Gene_expression of Tnf 142 0.59 92.27 55.47 99.96
143 INT10166 Localization of Tnf 237 0.81 153.95 88.64 99.96
144 INT121961 Positive_regulation of Gene_expression of Phospho1 2 0.15 2.8 3.57 99.96
145 INT112711 Gene_expression of Phospho1 11 0.21 5.65 8.34 99.96
146 INT92669 Gene_expression of Bdnf 309 0.78 178.26 116.68 99.96
147 INT5050 Regulation of Localization of Calca 149 0.62 41.25 148.57 99.96
148 INT29170 Negative_regulation of Gene_expression of Il1b 25 0.59 16.36 13.68 99.96
149 INT23344 Gene_expression of Alox5 60 0.75 28.2 13.82 99.96
150 INT64440 Gene_expression of Pnoc 66 0.78 13.61 41.76 99.96
151 INT53083 Gene_expression of Ptgs2 153 0.78 90.04 50.39 99.96
152 INT5993 Positive_regulation of Nts 122 0.70 26.82 70.45 99.96
153 INT1902 Gene_expression of Cck 348 0.78 70.33 241.92 99.96
154 INT68970 Positive_regulation of Pnoc 33 0.67 9.29 19.08 99.96
155 INT5513 Negative_regulation of Pomc 295 0.59 60.9 158.63 99.96
156 INT4843 Gene_expression of Npff 50 0.78 12.92 36.37 99.96
157 INT27798 Gene_expression of Ntrk2 111 0.78 56.08 42.68 99.96
158 INT4631 Positive_regulation of Sst 127 0.70 17.37 83.29 99.96
159 INT66531 Gene_expression of Pnoc 88 0.78 22.9 65.11 99.96
160 INT20066 Gene_expression of Mdk 38 0.76 21.41 13.4 99.96
161 INT76836 Positive_regulation of Ednra 6 0.55 2.65 2.72 99.96
162 INT110241 Negative_regulation of Positive_regulation of Lyz2 1 0.00 0.97 0.79 99.96
163 INT110240 Positive_regulation of Lyz2 1 0.00 0.96 0.79 99.96
164 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57 99.96
165 INT52188 Positive_regulation of Des 2 0.16 1.56 1.63 99.96
166 INT5650 Gene_expression of Mpo 117 0.77 80.27 26.42 99.96
167 INT1614 Gene_expression of Oprl1 164 0.78 31.43 127.74 99.96
168 INT946 Negative_regulation of Nts 60 0.57 4.61 34.44 99.96
169 INT49219 Gene_expression of Hrh1 28 0.75 13.77 14.99 99.96
170 INT96911 Positive_regulation of Phosphorylation of Mapk14 46 0.70 43.03 15.15 99.96
171 INT96914 Phosphorylation of Mapk14 168 0.82 108.46 53.32 99.96
172 INT108792 Positive_regulation of RGS4 1 0.47 0.54 1.87 99.96
173 INT94952 Positive_regulation of Mapk14 305 0.70 197.83 186.61 99.92
174 INT2542 Localization of Calca 2008 0.81 518.3 1408.65 99.92
175 INT9131 Positive_regulation of Prkcg 431 0.70 130.8 302.41 99.92
176 INT94953 Negative_regulation of Mapk14 156 0.59 104.77 91.51 99.92
177 INT9381 Positive_regulation of TRPV1 523 0.70 187.4 276.05 99.92
178 INT66029 Negative_regulation of Tnf 100 0.59 84.28 48.16 99.92
179 INT11936 Positive_regulation of Positive_regulation of Il6 34 0.50 26.85 10.59 99.92
180 INT12476 Negative_regulation of TRPV1 124 0.59 47.95 77.98 99.92
181 INT51029 Negative_regulation of Il1b 34 0.57 29.34 23.62 99.92
182 INT109430 Positive_regulation of Trpa1 119 0.70 44 49.14 99.92
183 INT76621 Positive_regulation of Cnr2 32 0.69 17.77 26.57 99.92
184 INT30887 Negative_regulation of Ngf 56 0.59 32.96 20.86 99.92
185 INT48080 Positive_regulation of Positive_regulation of Il1b 5 0.50 4.3 4.19 99.92
186 INT16255 Negative_regulation of Ntf3 21 0.51 12.92 11.93 99.92
187 INT48240 Binding of Ngf 46 0.46 23.51 24.42 99.92
188 INT100732 Gene_expression of F2RL1 55 0.78 38.89 19.45 99.92
189 INT3948 Regulation of Cck 291 0.62 58.07 255.88 99.92
190 INT27955 Negative_regulation of Gene_expression of Ngf 16 0.59 10.43 10.17 99.92
191 INT96624 Positive_regulation of Positive_regulation of Trpv1 62 0.70 20.5 34.28 99.92
192 INT9377 Positive_regulation of Positive_regulation of TRPV1 43 0.70 15.81 24.47 99.92
193 INT12602 Negative_regulation of Oprm1 190 0.59 36.11 177.85 99.92
194 INT6489 Positive_regulation of Gene_expression of Tnf 140 0.70 92.31 67.85 99.92
195 INT129303 Positive_regulation of NAV1 54 0.70 36.92 57.45 99.92
196 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35 99.92
197 INT1898 Regulation of Crh 220 0.62 61.33 102.64 99.92
198 INT7468 Negative_regulation of Localization of Oxt 109 0.59 9.46 66.79 99.92
199 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87 99.92
200 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15 99.92
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