P:IPN

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pChart

Pain Term
Category Pain type
Synonyms Inflammatory Pain
Pain Specific Yes
Documents 2231
Hot Single Events 200
Hot Interactions 180

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for IPN. They are ordered first by their pain relevance and then by number of times they were reported for IPN. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT276863 Gpr65 Regulation of Trpv1 1 0.25 1.78 1.75 100.00
2 INT136525 Binding of Prokr1 and Trpv1 1 0.39 2.9 3.76 100.00
3 INT136514 Binding of Grm1 and Grm5 4 0.12 1.8 3.9 100.00
4 INT22722 Binding of Chat and Hc3 1 0.39 0 0.28 100.00
5 INT37905 Cck Negative_regulation of Binding of Nts 1 0.64 0 0.61 100.00
6 INT37906 Cck Negative_regulation of Nts 1 0.64 0 0.61 100.00
7 INT168206 Binding of Pik3cd and Sh3 1 0.14 0.37 0.65 100.00
8 INT168205 Binding of Dlg4 and Pik3cd 1 0.11 0.37 0.65 100.00
9 INT136273 NGF Regulation of Gene_expression of BDNF 2 0.41 1.14 1.78 100.00
10 INT339291 Casp1 Positive_regulation of Il1 2 0.12 1.63 0.8 100.00
11 INT291011 Pomc Regulation of Gene_expression of ENG 1 0.08 0.86 0.91 100.00
12 INT113289 TRPV1 Regulation of Phosphorylation of Prkaca 1 0.02 0.1 0.37 100.00
13 INT121812 IL6 Regulation of OPRM1 1 0.22 0.27 0.65 99.92
14 INT330379 Gene_expression of IL10 Negative_regulation of Positive_regulation of MAPK14 1 0.00 1.95 1.18 99.86
15 INT136420 Binding of DeltaFosB and Rorb 1 0.03 0.66 0.97 99.84
16 INT159569 Negative_regulation of Alox5 Negative_regulation of Gene_expression of Fos 1 0.37 0.4 0.7 99.80
17 INT36783 Binding of Cck and Adarb1 1 0.27 0 0.41 99.68
18 INT141254 Ngf Regulation of Transcription of Trpv1 1 0.53 1.37 3.74 99.64
19 INT119313 Cpox Regulation of Gene_expression of Ptger2 1 0.02 0.6 0.74 99.64
20 INT119314 Ptgs1 Regulation of Gene_expression of Ptger2 1 0.01 0.6 0.73 99.64
21 INT147626 Spna1 Negative_regulation of Ctrc 1 0.01 0 0.24 99.60
22 INT147627 Spna1 Positive_regulation of Ctrc 1 0.01 0 0.24 99.60
23 INT150365 Camk2a Regulation of Gene_expression of Pomc 1 0.08 0.17 0.17 99.44
24 INT96906 Plxna3 Regulation of Regulation of Prkaca 1 0.17 0.71 1.08 99.40
25 INT69868 Binding of Ptgds and Ptger1 1 0.01 0 0.18 99.14
26 INT96905 Plxna3 Regulation of Regulation of Prkce 1 0.18 0.71 1.07 99.08
27 INT150366 Nfkb1 Regulation of Gene_expression of Pomc 1 0.03 0.17 0.17 99.08
28 INT149925 Negative_regulation of Cpox Negative_regulation of Gene_expression of Pde4d 1 0.01 0.39 0.84 99.04
29 INT163909 CCL2 Positive_regulation of Positive_regulation of Ccr2 1 0.05 0.19 0.36 98.80
30 INT348402 LPA Positive_regulation of Gene_expression of Ptgs2 1 0.01 0.62 0.48 98.56
31 INT138332 Binding of P2rx3 and F2rl1 1 0.35 0.25 0.59 98.32
32 INT124292 Binding of Trpv1 and F2rl1 1 0.46 1.1 0.81 98.24
33 INT182565 Ptger2 Regulation of Trpv1 1 0.25 1.34 1.73 97.96
34 INT182553 Ptger2 Regulation of Localization of Prkca 1 0.08 0.69 0.53 97.96
35 INT182557 Ptger2 Regulation of Regulation of Trpv1 1 0.25 0.68 0.52 97.96
36 INT182554 Ptger2 Regulation of Ptger1 1 0.11 0.68 0.52 97.96
37 INT233508 Tlr4 Regulation of Gene_expression of Gpr18 1 0.04 0.45 0.46 97.72
38 INT185489 Atp5o Negative_regulation of P2rx7 1 0.01 0.29 0.24 97.68
39 INT212658 KCNA1 Positive_regulation of Cort 1 0.00 2.58 3.36 97.28
40 INT106676 Binding of Trpv1 and Phax 18 0.34 4.19 12.36 97.24
41 INT147474 Nfe2l2 Positive_regulation of Hmox1 1 0.43 0.38 0.9 97.20
42 INT122349 Ngf Regulation of Trpv1 3 0.64 1.55 3.79 97.16
43 INT199392 Pklr Positive_regulation of Prok2 1 0.34 1.3 0.91 96.88
44 INT199393 Prok2 Positive_regulation of Prokr1 1 0.48 1.3 0.9 96.88
45 INT69869 Binding of Ptgdr and Ptgds 1 0.06 0 0.22 96.80
46 INT168723 Positive_regulation of Trpv1 Positive_regulation of Gene_expression of Calca 1 0.48 1.1 1.84 96.60
47 INT163908 CCL2 Positive_regulation of Ccr2 1 0.05 0.2 0.35 96.56
48 INT163906 CCL2 Positive_regulation of CCR2 1 0.18 0.2 0.35 96.32
49 INT132863 Positive_regulation of Ngf Positive_regulation of Bdnf 1 0.23 1.11 0.43 96.16
50 INT195931 Binding of OPRM1 and Trpv1 1 0.07 0.87 3.43 95.76
51 INT291962 Pag1 Negative_regulation of Gene_expression of Grin2b 1 0.17 1.56 0.92 95.52
52 INT199391 Pklr Positive_regulation of Prokr1 1 0.31 1.28 0.87 95.40
53 INT291966 Pag1 Positive_regulation of Gene_expression of Grin2b 1 0.19 1.91 1.06 95.36
54 INT143946 Binding of Pebp1 and Mastl 1 0.00 2.04 3.82 95.04
55 INT169603 Nppb Regulation of Npr1 1 0.26 0.95 0.69 95.00
56 INT263232 Prkcg Positive_regulation of Trpv4 1 0.12 1.1 1.02 94.80
57 INT132862 Ngf Positive_regulation of Bdnf 4 0.46 4.05 3.65 94.44
58 INT121726 Ngf Positive_regulation of Phosphorylation of Akt1 1 0.37 1.4 2.34 94.32
59 INT121728 Ngf Positive_regulation of Phosphorylation of Pik3cb 1 0.45 0.69 1.11 94.32
60 INT276864 Positive_regulation of Gpr65 Positive_regulation of Prkaca 1 0.16 0.74 0.97 94.28
61 INT103548 Binding of TRPV1 and TRPV3 3 0.37 1.82 2.28 94.24
62 INT104858 Prkaca Negative_regulation of Negative_regulation of TRPV1 2 0.10 0.41 0.64 94.20
63 INT301138 Nsa2 Positive_regulation of Il10 1 0.03 1.22 0.39 93.96
64 INT145853 Casp1 Positive_regulation of Mapk14 1 0.02 0.68 0.93 93.88
65 INT262577 Localization of Ngf Positive_regulation of Positive_regulation of Mapk14 1 0.05 0.92 0.75 93.84
66 INT233527 Tlr4 Positive_regulation of ADORA1 1 0.00 0.45 0.47 93.56
67 INT253072 Pbrgcsf1 Positive_regulation of Gene_expression of Prok2 1 0.15 0.44 0.33 93.56
68 INT247265 Mecp2 Regulation of Fos 1 0.25 0.38 0.52 93.44
69 INT166299 Binding of Mapk14 and Gpbar1 1 0.13 0.64 0.65 93.36
70 INT166302 Negative_regulation of Binding of Mapk14 and Gpbar1 1 0.12 0.64 0.65 93.36
71 INT166303 Adrbk1 Positive_regulation of Binding of Mapk14 and Gpbar1 1 0.22 0.65 0.65 93.36
72 INT263228 Prkcg Regulation of Trpv4 1 0.07 0.36 0.5 93.36
73 INT132683 Bdnf Positive_regulation of Phosphorylation of Grin2a 1 0.00 0.93 1.11 93.32
74 INT296448 Ush1c Regulation of Binding of Gria2 1 0.06 0.29 0.28 93.04
75 INT145592 Vamp1 Positive_regulation of Calca 1 0.01 0.28 0.73 93.00
76 INT76396 Il10 Negative_regulation of Il1b 2 0.65 1.89 1.08 92.76
77 INT233503 Tlr4 Positive_regulation of Adora2b 1 0.06 0.45 0.47 92.76
78 INT76397 Il10 Negative_regulation of Ngf 1 0.44 0.45 0.3 92.76
79 INT76395 Il10 Negative_regulation of Gene_expression of Ngf 1 0.45 0.45 0.3 92.76
80 INT276669 Negative_regulation of Prkcg Regulation of Nav1 1 0.21 0.68 1.82 92.52
81 INT276674 Negative_regulation of Nkx1-1 Regulation of Nav1 1 0.11 0.68 1.81 92.52
82 INT190130 Binding of CPOX and MRXS5 1 0.00 1.4 1.23 92.48
83 INT335435 Ngf Positive_regulation of Ltb4r 1 0.52 1.06 1.16 92.48
84 INT113243 TNF Positive_regulation of Transcription of OPRM1 1 0.23 0.84 0.51 92.48
85 INT276679 Prkcg Positive_regulation of Positive_regulation of Nkx1-1 1 0.07 0.94 3.08 92.00
86 INT195927 Binding of Prkaca and Trpv1 1 0.07 0.28 0.92 91.92
87 INT276676 Prkcg Regulation of Nav1 1 0.30 0.82 3.29 91.88
88 INT276678 Nkx1-1 Regulation of Nav1 1 0.15 0.88 3.31 91.88
89 INT147473 Nfe2l2 Positive_regulation of Gene_expression of Hmox1 1 0.74 0.49 0.39 91.84
90 INT263235 Trpv4 Regulation of Trpv1 1 0.17 0.7 0.5 91.04
91 INT138886 Binding of F11r and Tjp1 1 0.13 0.86 0.6 90.88
92 INT113242 TNF Regulation of Transcription of OPRM1 2 0.45 1.53 1.19 90.88
93 INT113241 TRAF3IP2 Regulation of Transcription of OPRM1 1 0.05 0.82 0.52 90.88
94 INT223866 Ltp Positive_regulation of Positive_regulation of Mapk1 2 0.46 0.75 2.61 90.40
95 INT125284 FSCN1 Positive_regulation of Positive_regulation of EPHB2 1 0.04 0.4 1.14 90.20
96 INT159774 Binding of GRM5 and TRPV1 1 0.40 0.5 0.51 90.16
97 INT354224 Bdnf Positive_regulation of Transcription of Accn3 1 0.09 1.04 0.95 89.60
98 INT240653 Ngf Positive_regulation of Positive_regulation of Bdnf 1 0.55 2.97 4.23 89.40
99 INT185917 Binding of AR and MAPK1 1 0.07 0.5 0.47 89.04
100 INT296484 Binding of Gria2 and GRIP1 1 0.04 4.52 4.59 88.84
101 INT139156 Binding of Gria1 and Gria2 1 0.23 0.64 1.72 88.84
102 INT127383 Neo1 Regulation of Localization of Mpo 1 0.14 0.7 0.79 88.68
103 INT121730 Pik3cb Regulation of Trpv1 1 0.58 0.54 1.09 88.56
104 INT339293 Casp1 Regulation of Localization of Il1 1 0.07 1.87 0.83 88.56
105 INT166300 Adrbk1 Positive_regulation of Negative_regulation of Gpbar1 1 0.39 0.63 0.58 88.48
106 INT267890 Arl10 Regulation of Insrr 1 0.00 0.43 0.54 88.40
107 INT267889 St13 Regulation of Insrr 1 0.00 0.43 0.54 88.40
108 INT143578 Olr404 Negative_regulation of Positive_regulation of Fos 1 0.01 0.39 0.93 88.32
109 INT113453 Ngf Positive_regulation of JUN 1 0.27 0.6 1.01 88.24
110 INT152113 Binding of NTSR1 and Ngf 3 0.33 2.09 2.62 88.16
111 INT120348 Negative_regulation of Binding of DES and MYC 1 0.06 0.18 0.58 88.16
112 INT162299 Negative_regulation of Adarb1 Negative_regulation of Gene_expression of Calca 1 0.01 0.93 1 88.08
113 INT139357 Nr1h2 Regulation of Gene_expression of Ptges 1 0.07 0.5 0.25 87.72
114 INT322132 Binding of Mbp and Trpv4 1 0.11 0.39 0.27 87.64
115 INT322127 Binding of Mbp and Ca2 1 0.01 0.39 0.27 87.64
116 INT322128 Binding of Ca2 and Trpv4 1 0.03 1.1 0.75 87.48
117 INT190788 Adcy8 Positive_regulation of Adcy1 1 0.23 0.77 0.77 87.40
118 INT120349 Binding of BDKRB1 and DES 1 0.05 0.17 0.58 87.28
119 INT120350 Binding of DES and MYC 1 0.05 0.17 0.58 87.28
120 INT117806 Binding of TRPV1 and Syt9 1 0.11 0.37 0.7 87.24
121 INT107219 Binding of P2rx7 and Atp5o 1 0.03 0.07 0.21 86.88
122 INT207411 Sst Negative_regulation of Gene_expression of Tacr1 1 0.05 0.76 0.69 86.88
123 INT315284 PRKG1 Positive_regulation of Nos1 1 0.33 0.85 1.56 86.76
124 INT66713 Binding of BDKRB1 and KNG1 2 0.22 0.39 1.53 86.76
125 INT120347 Binding of KNG1 and MYC 1 0.21 0.17 0.58 86.76
126 INT296472 Camk2a Positive_regulation of Prkaca 1 0.09 0.32 0.57 86.72
127 INT121729 Negative_regulation of Ngf Positive_regulation of Ephb1 1 0.24 0.69 1.22 86.36
128 INT121724 Ngf Positive_regulation of Ephb1 1 0.40 0.68 1.21 86.36
129 INT86263 Binding of Tacr3 and Tac2 1 0.16 0.52 1.13 86.32
130 INT149628 Il1b Regulation of Gene_expression of Ptgs2 1 0.30 0.84 0.84 86.16
131 INT223753 Tlr4 Positive_regulation of Gene_expression of Il10 4 0.32 1.93 0.78 85.96
132 INT206768 TP53 Positive_regulation of Ltp 2 0.01 5.83 10.21 85.92
133 INT107223 APEH Negative_regulation of P2rx7 1 0.00 0.13 0.21 85.84
134 INT296463 Binding of Gria1 and Pick1 1 0.16 0.32 0.59 85.84
135 INT100559 Binding of Grin1 and LOC502940 1 0.13 0.61 0.8 85.76
136 INT140659 Phax Positive_regulation of Trpv1 3 0.49 0.68 2.18 85.44
137 INT352196 Igkv12-66 Negative_regulation of Gm10404 1 0.00 1.62 1.34 85.44
138 INT281077 Binding of Gria2 and Gria3 2 0.24 0.35 1.19 85.36
139 INT149626 Il1b Regulation of Gene_expression of Tnf 1 0.41 0.83 0.83 85.36
140 INT148173 Positive_regulation of Grm5 Positive_regulation of Phosphorylation of Mapk1 1 0.01 0.45 0.65 85.12
141 INT113452 Ngf Positive_regulation of Gene_expression of ASIC3 1 0.19 1.34 2.08 84.64
142 INT127585 Binding of CNR2 and Ctbp1 1 0.00 0.6 0.76 84.40
143 INT207410 Ptger2 Regulation of Gene_expression of Tacr1 1 0.02 0.69 0.65 84.40
144 INT121813 IL6 Positive_regulation of OPRM1 1 0.28 0.28 0.58 84.32
145 INT139225 Calca Negative_regulation of Icam1 1 0.44 1.13 1.06 84.24
146 INT131564 Binding of Npw and Npbwr1 3 0.41 0.35 1.46 84.24
147 INT296486 Binding of Pick1 and GRIP1 1 0.03 0.32 0.59 84.24
148 INT185937 NOS2 Regulation of Prkaca 1 0.03 1.08 0.82 84.12
149 INT127254 Binding of Gpr176 and Npbwr1 1 0.02 0.49 0.72 84.08
150 INT275285 Ros1 Positive_regulation of Tnfrsf1a 1 0.27 1.06 0.72 83.68
151 INT164990 Mif Positive_regulation of Gene_expression of Grina 1 0.24 0.53 0.6 83.08
152 INT127584 Binding of CNR1 and Ctbp1 1 0.00 0.6 0.75 82.88
153 INT326663 Bdnf Regulation of Positive_regulation of Arc 1 0.16 1.46 0.88 82.88
154 INT139230 Icam1 Negative_regulation of Cmklr1 1 0.19 1.13 1.07 82.84
155 INT139227 Icam1 Negative_regulation of Timp1 1 0.37 1.13 1.06 82.84
156 INT139226 Icam1 Negative_regulation of Calca 1 0.44 1.12 1.05 82.84
157 INT82023 Binding of Ntrk1 and Ngf 5 0.53 3.48 3.92 82.16
158 INT82025 Negative_regulation of Binding of Ntrk1 and Ngf 1 0.47 0.64 1.37 82.16
159 INT89938 Tlr4 Positive_regulation of Gene_expression of TNF 6 0.25 1.3 1.12 81.88
160 INT147475 co Positive_regulation of Gene_expression of Nfe2l2 1 0.01 0.57 0.36 81.84
161 INT139957 Binding of Man1b-rs and Gprasp1 1 0.00 0.08 0.85 81.60
162 INT82024 Binding of Ngfr and Ngf 2 0.33 1.48 1.05 81.52
163 INT82021 Negative_regulation of Binding of Ngfr and Ngf 1 0.29 0.32 0.69 81.52
164 INT164286 Alox5ap Positive_regulation of Cysltr2 1 0.19 1.11 0.61 81.48
165 INT164284 Ltb4r Positive_regulation of Alox5ap 1 0.34 1.1 0.6 81.48
166 INT63521 Negative_regulation of Ptgs2 Negative_regulation of Gene_expression of Fos 1 0.66 0.1 0.12 81.44
167 INT164285 Ltc4s Positive_regulation of Cysltr2 1 0.20 1.11 0.61 81.24
168 INT164283 Ltb4r Positive_regulation of Ltc4s 1 0.37 1.1 0.6 81.24
169 INT147472 co Positive_regulation of Gene_expression of Hmox1 1 0.01 0.57 0.36 81.20
170 INT139229 Calca Negative_regulation of Cmklr1 1 0.19 1.12 1.06 81.16
171 INT139231 Calca Negative_regulation of Timp1 1 0.36 1.11 1.05 81.16
172 INT262568 Prkaca Regulation of Trpv1 2 0.10 0.65 1.38 81.04
173 INT149390 Foxm1 Positive_regulation of Trpa1 1 0.28 0.31 0.94 81.00
174 INT164287 Ltb4r Positive_regulation of Cysltr2 2 0.41 1.88 1.02 80.96
175 INT164281 Ltb4r Positive_regulation of Cysltr1 2 0.32 1.87 1.02 80.96
176 INT190128 Positive_regulation of PTGER1 Negative_regulation of Gene_expression of CPOX 1 0.04 1.21 1.38 80.72
177 INT296456 Gria1 Negative_regulation of Rbm39 1 0.00 0.45 0.57 80.72
178 INT149389 Olfr1241 Positive_regulation of Trpa1 1 0.02 0.31 0.94 80.68
179 INT164282 Cysltr1 Positive_regulation of Cysltr2 1 0.17 1.1 0.6 80.56
180 INT140024 Tnf Positive_regulation of Gene_expression of Il1b 2 0.49 2.75 2.61 80.40
181 INT82022 Binding of Trib3 and Ngf 1 0.08 0.31 0.68 79.92
182 INT82020 Negative_regulation of Binding of Trib3 and Ngf 1 0.07 0.31 0.68 79.92
183 INT141870 Binding of Slc2a4 and Cav1 1 0.36 0.38 0.28 79.64
184 INT253585 Binding of IFN1@ and Csnk2a2 1 0.24 1.35 0.64 79.60
185 INT264953 Binding of POMC and TLR4 1 0.03 0.89 1.96 79.28
186 INT264947 Binding of POMC and TLR2 1 0.03 0.89 1.95 79.28
187 INT167466 Ccdc80 Negative_regulation of Tnf 1 0.01 0.76 0.88 78.80
188 INT84717 Il1b Regulation of Cpox 1 0.00 0.37 0.83 78.16
189 INT166301 Adrbk1 Positive_regulation of Localization of Trpv1 1 0.45 1.17 1.2 78.08
190 INT199389 Prok2 Positive_regulation of Localization of Il1f5 1 0.05 1.17 0.88 78.08
191 INT150643 Binding of Bdkrb2 and Trpa1 1 0.36 0.55 0.78 77.52
192 INT333966 Binding of Il6r and Il6st 1 0.01 1.74 1.1 77.52
193 INT278948 LEP Positive_regulation of Gene_expression of PTGER2 1 0.09 4.04 2.69 77.48
194 INT278962 LEP Positive_regulation of CPOX 1 0.05 1.33 1 77.48
195 INT281085 Binding of Gria2 and Nsf 2 0.26 0.4 0.94 77.36
196 INT269508 Binding of HTN1 and CFP 1 0.00 0 0.08 77.36
197 INT166165 Binding of TGFB3 and Bmp2 1 0.00 0 0.3 77.24
198 INT18026 Binding of Oprd1 and Oprm1 4 0.40 0.83 3.53 77.04
199 INT126717 Binding of Il6 and Il6st 3 0.21 3.35 2.22 76.96
200 INT296459 Binding of Dlg1 and Gria1 1 0.02 0.23 0.31 76.80

Single Events

The table below shows the top 200 pain related interactions that have been reported for IPN. They are ordered first by their pain relevance and then by number of times they were reported in IPN. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT1303 Negative_regulation of Npr1 278 0.55 35.1 156.78 100.00
2 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08 100.00
3 INT49553 Regulation of Gene_expression of Gfap 42 0.62 17.04 23.65 100.00
4 INT24711 Negative_regulation of Spna1 22 0.35 14.75 3.59 100.00
5 INT9233 Negative_regulation of Gene_expression of IL1B 114 0.59 56.99 41.82 100.00
6 INT5591 Regulation of Gene_expression of Fos 425 0.62 129.06 265.78 100.00
7 INT48404 Regulation of Gene_expression of Icam1 21 0.62 15.1 7.81 100.00
8 INT24569 Negative_regulation of Pain1 26 0.41 21.82 21.08 100.00
9 INT287 Localization of Cck 518 0.81 86.84 364.04 100.00
10 INT16229 Negative_regulation of Ccbp2 1 0.19 0 1.37 100.00
11 INT24326 Gene_expression of Ngf 346 0.78 218.67 184.71 100.00
12 INT142425 Binding of Magmas-ps1 1 0.29 0.87 0.98 100.00
13 INT21467 Negative_regulation of Binding of Cck 18 0.57 2.84 11.91 100.00
14 INT11837 Positive_regulation of MHB 8 0.69 1.07 5.55 100.00
15 INT178828 Regulation of Pain1 12 0.14 16.1 15.64 100.00
16 INT1613 Binding of Nts 58 0.48 10.55 28.18 100.00
17 INT77855 Gene_expression of Pain1 55 0.75 67.42 54.1 100.00
18 INT9382 Regulation of TRPV1 149 0.62 53.99 77.46 100.00
19 INT73901 Negative_regulation of Transcription of IL1B 3 0.53 0.46 1.57 100.00
20 INT130597 Regulation of Gene_expression of Slco1c1 1 0.07 0.76 1.37 100.00
21 INT145880 Regulation of Regulation of Pgp 1 0.37 1.26 1.45 100.00
22 INT125384 Positive_regulation of Pain1 23 0.49 17.1 14.83 100.00
23 INT37975 Negative_regulation of Binding of Ripk2 1 0.57 0 0.75 100.00
24 INT168681 Gene_expression of BMS1 5 0.37 2.7 1.62 100.00
25 INT118207 Binding of Ghrl 11 0.47 7.39 3.52 100.00
26 INT170855 Negative_regulation of GOPC 188 0.38 70.92 15.41 100.00
27 INT51017 Positive_regulation of Icam1 113 0.70 81.16 35.55 99.98
28 INT34033 Positive_regulation of Positive_regulation of Pde4dl1 1 0.35 0.34 2 99.98
29 INT116996 Regulation of Pgp 9 0.51 7.51 8.01 99.98
30 INT48407 Positive_regulation of Gene_expression of Icam1 61 0.70 57.91 21.54 99.98
31 INT34032 Negative_regulation of Positive_regulation of Pde4dl1 1 0.40 0.15 1.01 99.98
32 INT70996 Positive_regulation of Positive_regulation of Icam1 8 0.60 6.02 3.74 99.98
33 INT51602 Gene_expression of Grm5 59 0.75 17.29 26.99 99.98
34 INT58061 Gene_expression of Trpv1 1117 0.78 451.54 637.59 99.96
35 INT89054 Positive_regulation of Gene_expression of Trpv1 156 0.70 90.78 102.03 99.96
36 INT11185 Regulation of Slco1c1 15 0.44 6.88 4.52 99.96
37 INT7134 Localization of KNG1 127 0.79 65.73 67.97 99.96
38 INT111451 Regulation of ADIPOQ 24 0.56 18.81 2.47 99.96
39 INT75918 Negative_regulation of Negative_regulation of Cpox 19 0.23 10.05 14.4 99.96
40 INT28265 Positive_regulation of Calca 62 0.70 29.1 41.17 99.96
41 INT87611 Gene_expression of Mrgprc 6 0.64 1.92 4.84 99.96
42 INT1898 Regulation of Crh 220 0.62 61.33 102.64 99.96
43 INT264974 Positive_regulation of Negative_regulation of FPR1 1 0.27 0.1 1.02 99.96
44 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 99.92
45 INT9381 Positive_regulation of TRPV1 523 0.70 187.4 276.05 99.92
46 INT2542 Localization of Calca 2008 0.81 518.3 1408.65 99.92
47 INT18357 Gene_expression of TRPV1 825 0.78 307.11 382.81 99.92
48 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35 99.92
49 INT112999 Gene_expression of Nosip 1 0.78 3.17 2.28 99.92
50 INT82448 Gene_expression of S100a8 246 0.77 236.72 84.02 99.92
51 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86 99.92
52 INT95646 Negative_regulation of Faah 63 0.59 25.61 36.78 99.92
53 INT83602 Positive_regulation of Gene_expression of TRPV1 114 0.70 51.19 56.35 99.92
54 INT31394 Negative_regulation of Localization of Oprd1 3 0.39 2.38 7.89 99.92
55 INT134596 Regulation of Trpa1 32 0.62 18.78 17.02 99.92
56 INT134597 Binding of Trpa1 21 0.48 9.41 9.74 99.92
57 INT113039 Binding of Bdkrb1 9 0.48 5.71 4.51 99.92
58 INT14126 Gene_expression of Grina 13 0.67 4.63 4.57 99.92
59 INT236487 Positive_regulation of Gene_expression of Grina 2 0.08 1.77 1.45 99.92
60 INT77435 Positive_regulation of Nos2 343 0.70 208.49 91.43 99.90
61 INT79093 Positive_regulation of Nos1 101 0.70 46.89 59.61 99.90
62 INT89084 Gene_expression of Slco1c1 15 0.51 4.92 6.02 99.90
63 INT11836 Regulation of MHB 2 0.23 0.07 1.67 99.90
64 INT157515 Gene_expression of Lad1 1 0.00 0 0.25 99.90
65 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02 99.88
66 INT22844 Positive_regulation of Pkib 2 0.33 2 1.34 99.88
67 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 99.86
68 INT54284 Negative_regulation of Gene_expression of Oprd1 16 0.42 4.56 14.34 99.86
69 INT108352 Regulation of Phosphorylation of Prkaca 8 0.59 0.68 1.53 99.86
70 INT4259 Positive_regulation of Npr1 262 0.70 49.37 123.11 99.84
71 INT32889 Positive_regulation of Pde4dl1 6 0.49 1.69 4.6 99.84
72 INT16260 Gene_expression of Bdnf 671 0.78 283.44 339.1 99.84
73 INT886 Gene_expression of Pomc 676 0.78 129.87 295.98 99.84
74 INT36054 Transcription of IL1B 53 0.72 32.64 17.31 99.84
75 INT16253 Positive_regulation of Gene_expression of Bdnf 196 0.70 92.67 113.01 99.84
76 INT5497 Positive_regulation of Crh 299 0.70 125.54 131.14 99.84
77 INT103681 Negative_regulation of Gene_expression of Krt7 1 0.01 0.97 1.12 99.84
78 INT49750 Negative_regulation of CPOX 735 0.58 360.06 274.19 99.84
79 INT92434 Phosphorylation of Mapk1 287 0.82 91.65 83.46 99.84
80 INT4260 Negative_regulation of Positive_regulation of Npr1 29 0.43 4.39 19.57 99.84
81 INT7675 Gene_expression of ENG 146 0.77 45.35 34.6 99.84
82 INT1163 Negative_regulation of Rbm39 64 0.29 16.8 34.74 99.84
83 INT95930 Negative_regulation of Gria2 63 0.56 18.37 17.04 99.84
84 INT6277 Positive_regulation of Gene_expression of Pomc 76 0.70 21.45 31.09 99.84
85 INT120966 Positive_regulation of Pik3cb 34 0.68 15.15 16.59 99.84
86 INT342814 Regulation of Gene_expression of PARPBP 1 0.19 1.51 3.48 99.84
87 INT67620 Negative_regulation of Gene_expression of Bdnf 53 0.59 22.45 28.5 99.84
88 INT276837 Positive_regulation of Transcription of Gpr65 1 0.61 1.76 1.62 99.84
89 INT276848 Transcription of Gpr65 1 0.63 1.75 1.61 99.84
90 INT127067 Binding of FosB 2 0.37 0.66 1.06 99.84
91 INT35835 Positive_regulation of Htr2a 17 0.67 10.68 9.81 99.84
92 INT99592 Regulation of Adrbk1 3 0.61 1.46 2.84 99.84
93 INT72073 Positive_regulation of Gene_expression of NPFF 2 0.60 1.25 1.77 99.84
94 INT121723 Regulation of Positive_regulation of Pik3cb 1 0.44 0.61 1.29 99.84
95 INT48406 Gene_expression of Icam1 277 0.78 238.28 81.71 99.82
96 INT11377 Positive_regulation of Ngf 331 0.70 206.5 238 99.82
97 INT98621 Regulation of Trpv1 121 0.62 79.24 75.23 99.82
98 INT48952 Negative_regulation of Nos2 204 0.59 101.73 53.15 99.82
99 INT1243 Regulation of ADRB2 16 0.54 1.84 5.66 99.82
100 INT91916 Gene_expression of P2rx3 51 0.78 21.2 19.05 99.82
101 INT14096 Negative_regulation of Son 8 0.38 0 4.15 99.82
102 INT48956 Negative_regulation of Positive_regulation of Nos2 34 0.46 13.15 11.15 99.82
103 INT64076 Positive_regulation of Kcnma1 47 0.40 11.52 24.19 99.82
104 INT1562 Localization of Crh 499 0.81 126.74 236.68 99.80
105 INT5202 Positive_regulation of Gene_expression of Fos 1163 0.70 319.28 684 99.80
106 INT16654 Gene_expression of Insrr 138 0.46 58.96 75.68 99.80
107 INT54934 Negative_regulation of smc 7 0.08 1.48 1.66 99.80
108 INT12087 Regulation of Localization of TNF 44 0.62 28.71 15.17 99.80
109 INT52106 Negative_regulation of Localization of IL8 57 0.52 22.81 20.8 99.80
110 INT74422 Regulation of Localization of IL8 21 0.62 10.19 5.99 99.80
111 INT107522 Regulation of Grm5 9 0.44 6.42 11.46 99.80
112 INT158855 Binding of Mrgprx1 1 0.27 0.9 1.28 99.80
113 INT72074 Regulation of NPFF 6 0.39 3.07 5.48 99.80
114 INT81664 Positive_regulation of Gene_expression of Pnoc 12 0.68 2.51 9.75 99.78
115 INT156302 Positive_regulation of Phosphorylation of Trpv4 2 0.46 0.92 0.68 99.78
116 INT87687 Positive_regulation of Trpv1 409 0.70 210.24 257.59 99.76
117 INT42980 Gene_expression of GAD1 139 0.69 94.77 45.11 99.76
118 INT73338 Gene_expression of Faah 21 0.77 6.72 10.73 99.76
119 INT97773 Gene_expression of Gpr18 1 0.29 0.25 0.32 99.76
120 INT2211 Negative_regulation of Abat 267 0.59 66.51 200.98 99.74
121 INT48718 Positive_regulation of PRKCA 109 0.69 36.16 46.49 99.74
122 INT92518 Gene_expression of Grin2b 131 0.78 65.52 80.91 99.72
123 INT93451 Positive_regulation of Gene_expression of Grin2b 43 0.70 29.09 31.89 99.72
124 INT86698 Gene_expression of Cav1 38 0.78 16.37 11.75 99.72
125 INT25363 Negative_regulation of Trpv1 144 0.59 64.78 75.7 99.72
126 INT112207 Binding of Nav1 27 0.47 7.1 15.43 99.72
127 INT166240 Regulation of Gene_expression of Cav1 3 0.51 1.03 0.43 99.72
128 INT15308 Localization of Chat 29 0.81 2.35 8.47 99.70
129 INT95787 Positive_regulation of Mapk1 568 0.70 226.51 220.94 99.70
130 INT95788 Positive_regulation of Positive_regulation of Mapk1 83 0.69 24.75 25.84 99.70
131 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 99.70
132 INT4893 Gene_expression of Tacr1 366 0.78 129.67 213.92 99.68
133 INT4736 Gene_expression of Chat 67 0.77 17.15 14.24 99.68
134 INT35801 Regulation of Alms1 34 0.38 20.88 12.38 99.68
135 INT4892 Positive_regulation of Gene_expression of Tacr1 56 0.69 25.64 34.69 99.68
136 INT5979 Gene_expression of Oprd1 428 0.78 75.64 320.32 99.68
137 INT2366 Binding of Cck 192 0.48 30.64 163.46 99.68
138 INT4473 Negative_regulation of Vps13a 1 0.07 0 0.72 99.68
139 INT4637 Binding of Adarb1 132 0.41 14.48 67.76 99.68
140 INT6861 Negative_regulation of Gfap 32 0.58 13.71 7.22 99.68
141 INT8881 Regulation of Gene_expression of Tacr1 38 0.61 17.49 27.19 99.68
142 INT3969 Positive_regulation of Sds 27 0.69 7.52 12.31 99.68
143 INT276825 Positive_regulation of Gene_expression of Gpr68 1 0.29 1.1 0.62 99.68
144 INT5228 Positive_regulation of Fos 934 0.70 209.8 503.87 99.66
145 INT6669 Negative_regulation of Positive_regulation of Fos 98 0.59 23.5 56.82 99.66
146 INT66383 Phosphorylation of Prkaca 143 0.80 30.85 43.38 99.66
147 INT62012 Gene_expression of Trafd1 11 0.31 8.53 3.13 99.64
148 INT4936 Localization of Tacr1 125 0.80 35.7 107.7 99.64
149 INT57878 Positive_regulation of Gene_expression of Egr1 36 0.70 20.42 14.45 99.64
150 INT9781 Binding of INSRR 64 0.31 19.1 25.2 99.64
151 INT23435 Positive_regulation of NGF 54 0.70 32.41 30.11 99.64
152 INT3950 Gene_expression of Ptger2 293 0.77 122.28 62.42 99.64
153 INT17546 Negative_regulation of Ngf 135 0.59 60.28 77.19 99.64
154 INT82305 Regulation of Localization of Bdnf 10 0.40 3 3.62 99.64
155 INT1004 Regulation of Sst 140 0.62 18.52 94.84 99.64
156 INT1635 Gene_expression of Vip 245 0.78 53.36 88.13 99.62
157 INT50058 Negative_regulation of Cpox 907 0.58 426.28 428.29 99.60
158 INT6381 Negative_regulation of Chat 51 0.59 19.68 15.86 99.60
159 INT145879 Positive_regulation of Gene_expression of Pgp 2 0.30 1.23 1.63 99.60
160 INT135258 Gene_expression of Pgp 4 0.47 1.28 1.96 99.60
161 INT67190 Gene_expression of Muc2 24 0.78 18.8 2.08 99.60
162 INT5324 Binding of Htr2a 23 0.47 7.14 14.66 99.60
163 INT63854 Regulation of Gene_expression of Prkcg 27 0.56 9.41 14.15 99.60
164 INT12569 Localization of Oprd1 94 0.81 23.81 104.56 99.58
165 INT12339 Localization of IL8 437 0.81 251.87 117.39 99.58
166 INT6585 Positive_regulation of Insrr 110 0.52 40.67 89.9 99.58
167 INT32935 Binding of Pgrmc1 4 0.21 1.14 2.84 99.58
168 INT96179 Gene_expression of Slc38a3 2 0.68 0.52 0.79 99.58
169 INT49171 Gene_expression of Nos1 241 0.78 140.7 104.76 99.56
170 INT5540 Positive_regulation of Oprm1 344 0.70 76.77 319.71 99.56
171 INT64111 Negative_regulation of Gene_expression of Nos1 22 0.57 8.96 6.02 99.56
172 INT5922 Gene_expression of Rtn4 27 0.48 12.7 17.86 99.56
173 INT75546 Transcription of Rtn4 1 0.06 2.87 5.03 99.56
174 INT12463 Binding of FPR1 21 0.48 3.16 7.98 99.56
175 INT12707 Negative_regulation of Binding of FPR1 9 0.59 1.45 3.72 99.56
176 INT1456 Regulation of Oprl1 61 0.62 19.5 52.87 99.54
177 INT46460 Gene_expression of NAV1 288 0.78 135.51 305.75 99.52
178 INT5680 Gene_expression of Ngf 530 0.78 264.29 310.56 99.52
179 INT61873 Gene_expression of Arc 128 0.78 128.25 52.24 99.52
180 INT105287 Positive_regulation of Slco1c1 24 0.34 15.41 6.81 99.52
181 INT14009 Gene_expression of Sst 66 0.77 19.6 37.3 99.52
182 INT119470 Regulation of Ptger4 6 0.43 3.94 3.24 99.52
183 INT52692 Gene_expression of Ptgs2 160 0.78 85.06 55.73 99.52
184 INT48953 Positive_regulation of Nos2 486 0.70 239.85 131.87 99.52
185 INT156299 Phosphorylation of Trpv4 8 0.80 2.46 2.31 99.52
186 INT73427 Localization of P2rx7 24 0.79 8.65 9.87 99.52
187 INT78955 Regulation of Gene_expression of Ptgs2 12 0.62 7.22 6.02 99.52
188 INT82761 Regulation of Positive_regulation of Mapk3 3 0.40 1.34 1.52 99.50
189 INT18755 Positive_regulation of Rvm 79 0.60 60 92.93 99.48
190 INT106720 Positive_regulation of Adcy1 30 0.50 22.05 22.68 99.48
191 INT3537 Positive_regulation of Car2 413 0.56 103.51 94.35 99.48
192 INT19771 Positive_regulation of PAG1 69 0.61 75.61 76.88 99.48
193 INT158858 Binding of Mrgprc 1 0.31 0.9 1.28 99.48
194 INT45266 Negative_regulation of Nenf 3 0.38 2.46 3.59 99.48
195 INT147029 Positive_regulation of Accn4 2 0.19 1.26 1.73 99.48
196 INT66531 Gene_expression of Pnoc 88 0.78 22.9 65.11 99.46
197 INT728 Positive_regulation of Penk 1068 0.70 186.9 636.87 99.46
198 INT9237 Regulation of Gene_expression of IL1B 49 0.62 30.69 20.34 99.44
199 INT57874 Gene_expression of Egr1 113 0.78 68.46 24.95 99.44
200 INT7994 Gene_expression of Lta 113 0.67 69.81 19.59 99.44
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