P:Inflammatory mediators

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pChart

Pain Term
Category Family
Synonyms None
Pain Specific No
Documents 1959
Hot Single Events 200
Hot Interactions 200

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Inflammatory mediators. They are ordered first by their pain relevance and then by number of times they were reported for Inflammatory mediators. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT153751 Regulation of Binding of CCL2 and Crp 1 0.03 1.8 0.65 100.00
2 INT120319 Ghrh Regulation of Ngf 1 0.25 1.89 2.11 100.00
3 INT104855 Prkaca Regulation of TRPV1 3 0.06 1.52 1.92 100.00
4 INT195117 Ptgs2 Positive_regulation of Gene_expression of Il6 1 0.10 3.26 1.16 100.00
5 INT306935 Tnfsf12 Positive_regulation of Gene_expression of Cxcl10 1 0.03 3.55 0.55 100.00
6 INT48715 PTGER2 Regulation of Gene_expression of SERPINE1 1 0.21 0.6 0.44 100.00
7 INT48716 IL1B Regulation of Gene_expression of SERPINE1 1 0.42 0.59 0.44 100.00
8 INT182771 ROS1 Positive_regulation of NFKB1 Positive_regulation of CRP 1 0.00 3.83 0.28 100.00
9 INT102691 RETNLB Positive_regulation of ITGAL 1 0.01 0.45 0.45 100.00
10 INT120317 Ghrh Regulation of Positive_regulation of Ngf 1 0.25 0.95 1.06 100.00
11 INT120311 Ghrh Regulation of Gene_expression of Ngf 1 0.25 0.95 1.06 100.00
12 INT209924 IL1B Negative_regulation of PPARA 1 0.20 4.38 2.17 100.00
13 INT120316 Ghrh Regulation of Il6 1 0.11 0.95 1.05 100.00
14 INT120310 Ghrh Regulation of Positive_regulation of Il6 1 0.18 0.95 1.05 100.00
15 INT120312 Ghrh Regulation of Tnf 1 0.26 0.95 1.05 100.00
16 INT120314 Ghrh Regulation of Positive_regulation of Tnf 1 0.43 0.95 1.05 100.00
17 INT226785 Angpt2 Positive_regulation of Localization of Lep 1 0.01 1.65 0.36 100.00
18 INT276668 Ngf Regulation of Nav1 1 0.09 0.98 1.85 100.00
19 INT177457 Il1 Positive_regulation of Gene_expression of Il6 3 0.16 4.47 1.35 100.00
20 INT224583 CSF2 Positive_regulation of IL1RN 1 0.02 1.3 0.88 100.00
21 INT224585 IL1B Positive_regulation of IL1RN 1 0.02 1.3 0.87 100.00
22 INT208946 Positive_regulation of Tacr1 Positive_regulation of Gene_expression of S100a8 1 0.02 1.11 0.8 100.00
23 INT190527 TNF Positive_regulation of Gene_expression of Ros1 1 0.01 1.02 0.68 100.00
24 INT283049 Car2 Positive_regulation of Trpa1 1 0.20 1.33 0.67 100.00
25 INT285758 RETNLB Positive_regulation of Gene_expression of TIMP1 1 0.01 1.79 0.55 100.00
26 INT320694 C5 Regulation of Gene_expression of Il2 1 0.03 2.15 0.34 100.00
27 INT320692 C5 Regulation of Gene_expression of Il12a 1 0.03 2.15 0.34 100.00
28 INT333893 Negative_regulation of HDAC9 Negative_regulation of Gene_expression of TNF 1 0.09 1.03 0.34 100.00
29 INT320693 C5 Regulation of Gene_expression of Il6 1 0.04 2.15 0.34 100.00
30 INT320696 C5 Regulation of Gene_expression of TNF 1 0.34 2.15 0.34 100.00
31 INT320691 C5 Regulation of Gene_expression of Il1 1 0.06 2.15 0.34 100.00
32 INT349506 S100a8 Positive_regulation of Gene_expression of Nos2 1 0.02 0.67 0.28 100.00
33 INT306941 Tnfsf12 Positive_regulation of Gene_expression of CCL2 1 0.03 1.65 0.27 100.00
34 INT306937 Tnfsf12 Positive_regulation of Gene_expression of Vcam1 1 0.05 1.79 0.27 100.00
35 INT306942 Tnfsf12 Positive_regulation of Gene_expression of ICAM1 1 0.04 1.78 0.27 100.00
36 INT292571 Positive_regulation of F2RL1 Positive_regulation of Localization of IL6 1 0.07 0.8 0.27 100.00
37 INT273046 Vip Negative_regulation of Gene_expression of Adcyap1 1 0.20 1.14 0.21 100.00
38 INT348059 Dbi Negative_regulation of Binding of Mpo 1 0.08 0.43 0.19 100.00
39 INT288349 TNF Positive_regulation of Gene_expression of Mcpt1 1 0.02 1.1 0.18 100.00
40 INT288351 Mcpt1 Positive_regulation of Gene_expression of TNF 1 0.02 1.1 0.18 100.00
41 INT290670 Binding of Nos2 and Ppara 1 0.17 0.41 0.16 100.00
42 INT182772 ROS1 Positive_regulation of NFKB1 Positive_regulation of IL1B 1 0.00 1.89 0.14 100.00
43 INT182773 ROS1 Positive_regulation of NFKB1 Positive_regulation of IL6 1 0.00 1.9 0.14 100.00
44 INT182780 NFKB1 Positive_regulation of IL1B 1 0.00 1.8 0.14 100.00
45 INT182782 NFKB1 Positive_regulation of IL6 1 0.00 1.8 0.14 100.00
46 INT140663 TRPV1 Regulation of Localization of Trpv1 1 0.14 0.18 0.09 100.00
47 INT278378 Hps5 Positive_regulation of Gene_expression of S100a8 1 0.00 0.42 0.09 100.00
48 INT179932 Trib3 Negative_regulation of Positive_regulation of Mmp9 1 0.01 0.41 0.05 100.00
49 INT179933 Trib3 Negative_regulation of Gene_expression of Mmp9 1 0.01 0.41 0.05 100.00
50 INT129912 Skiv2l Negative_regulation of Gene_expression of PTGS2 1 0.00 0.87 0.54 99.92
51 INT123397 F2 Positive_regulation of Gene_expression of PTAFR 1 0.05 0.51 0.32 99.92
52 INT140664 TRPV1 Regulation of sar 1 0.00 0.18 0.09 99.92
53 INT273171 PDE4A Regulation of IL8 1 0.05 0.53 0.15 99.86
54 INT139723 PROC Positive_regulation of MAPK8 1 0.01 2.98 2.33 99.80
55 INT231340 INCENP Regulation of Gene_expression of IL6 1 0.01 1.09 0.47 99.80
56 INT139722 PROC Positive_regulation of CDCP1 1 0.00 1.61 1.29 99.80
57 INT139724 PROC Positive_regulation of MAPK14 1 0.00 1.57 1.25 99.80
58 INT172834 Binding of IL6 and T2dm2 1 0.00 6.4 1.4 99.70
59 INT65986 IL1B Positive_regulation of PTGS2 3 0.32 2.05 1.03 99.56
60 INT65985 IL1B Positive_regulation of Gene_expression of PTGS2 3 0.23 2.62 0.71 99.56
61 INT153750 Binding of CCL2 and Crp 1 0.02 1.8 0.65 99.54
62 INT341534 INSRR Positive_regulation of F2RL1 1 0.00 1.4 0.7 99.52
63 INT193480 Binding of ABCA1 and IRF6 1 0.00 1.08 0.46 99.40
64 INT123398 TPSAB1 Positive_regulation of Gene_expression of PTAFR 1 0.14 0.51 0.32 99.40
65 INT202547 IGHE Positive_regulation of Localization of IL13 1 0.04 0.44 0.05 99.24
66 INT60626 Crh Positive_regulation of Localization of Pomc 7 0.54 2.3 1.99 99.16
67 INT338043 F2 Positive_regulation of Localization of Prkca 1 0.04 0.1 0.2 99.16
68 INT280846 Crh Positive_regulation of Localization of POMC 1 0.03 0.37 0.16 99.16
69 INT342992 Negative_regulation of PTAFR Negative_regulation of Gene_expression of HIST2H2AA3 1 0.01 0.4 0.78 99.12
70 INT217278 Kitl Regulation of Gene_expression of Ptges 1 0.02 0.1 0.05 99.04
71 INT144248 CGA Regulation of Positive_regulation of NFKB1 1 0.15 1.66 0.61 99.00
72 INT144256 CGA Regulation of Gene_expression of NFKB1 1 0.21 1.66 0.61 99.00
73 INT144249 CGA Regulation of Gene_expression of TNF 1 0.13 0.83 0.31 99.00
74 INT269180 LEP Positive_regulation of Localization of TNF 1 0.01 0.99 0.21 99.00
75 INT196632 IL1B Positive_regulation of F2RL1 2 0.05 1.52 0.84 98.96
76 INT274531 Il6 Regulation of Localization of Lpl 1 0.04 1.49 0.33 98.96
77 INT274530 Il6 Regulation of Lpl 1 0.07 1.48 0.32 98.96
78 INT140662 Trpv1 Regulation of sar 1 0.01 0.18 0.09 98.90
79 INT342988 HCL1 Positive_regulation of TRPV1 1 0.04 1.15 1.21 98.88
80 INT243678 Binding of GSR and Ugcg 2 0.03 2.84 0.83 98.88
81 INT337293 PTAFR Positive_regulation of Positive_regulation of TLR4 1 0.62 1.43 0.28 98.88
82 INT202542 IGHE Positive_regulation of Localization of IL4 1 0.06 0.44 0.05 98.84
83 INT202566 Re Positive_regulation of Localization of IL4 1 0.00 0.44 0.05 98.84
84 INT196638 TNF Positive_regulation of F2RL1 2 0.09 1.52 0.84 98.72
85 INT90387 ROS1 Positive_regulation of NFKB1 4 0.32 2.35 0.87 98.64
86 INT338042 F2r Positive_regulation of Localization of Prkca 1 0.06 0.1 0.2 98.64
87 INT165637 Ptpn6 Negative_regulation of Positive_regulation of Nfkb1 1 0.02 0.57 0.23 98.52
88 INT351311 Has1 Regulation of Gene_expression of MMP3 1 0.11 1.15 0.95 98.48
89 INT185373 IRF6 Positive_regulation of Gene_expression of TLR2 1 0.08 2.96 1.04 98.40
90 INT183387 Il6 Positive_regulation of Gene_expression of Il10 2 0.19 1.8 0.63 98.40
91 INT354224 Bdnf Positive_regulation of Transcription of Accn3 1 0.09 1.04 0.95 98.28
92 INT162790 Binding of TLR4 and NOD2 1 0.36 0.51 0.57 98.20
93 INT69881 Positive_regulation of Gtf3a Positive_regulation of Gene_expression of TNF 1 0.03 0.6 0.31 98.20
94 INT219280 Mapk14 Positive_regulation of Pla2g2a 1 0.33 0.46 0.61 98.12
95 INT219282 Mapk14 Positive_regulation of Pla2g1b 1 0.18 0.46 0.61 98.12
96 INT214615 FOXC1 Positive_regulation of Gene_expression of Ang 1 0.01 0.29 0.28 98.12
97 INT346835 Gene_expression of Efnb2 Positive_regulation of Phosphorylation of Grin2b 1 0.27 1.07 1.03 98.00
98 INT278965 LEP Positive_regulation of Gene_expression of NOS2 2 0.29 2.12 0.66 98.00
99 INT219277 Mapkapk2 Positive_regulation of Pla2g1b 1 0.03 0.46 0.61 97.96
100 INT219278 Mapkapk2 Positive_regulation of Pla2g2a 1 0.05 0.46 0.61 97.96
101 INT236365 Binding of CD40LG and IL6 3 0.20 4.16 1.42 97.88
102 INT342982 HCL1 Positive_regulation of SFTPA1 1 0.00 0.71 0.84 97.84
103 INT278368 Regulation of Binding of Il1 and Hps5 1 0.02 0.44 0.09 97.76
104 INT162789 Binding of TLR2 and NOD2 1 0.37 0.51 0.57 97.64
105 INT342991 HCL1 Positive_regulation of CALCA 1 0.03 0.71 0.84 97.56
106 INT324925 Ros1 Positive_regulation of Bdkrb1 1 0.08 0.67 0.6 97.56
107 INT101942 Binding of CD40 and CD40LG 16 0.23 15.24 4.01 97.32
108 INT228216 Positive_regulation of Mapk14 Regulation of Gene_expression of Tlr2 1 0.09 1.11 0.15 97.32
109 INT278371 Binding of Il1 and Hps5 1 0.02 0.44 0.09 97.32
110 INT197092 TNF Regulation of VEGFA 4 0.21 2.78 1.22 97.28
111 INT288376 IL17A Regulation of VEGFA 1 0.00 1.16 0.49 97.28
112 INT55901 Negative_regulation of Alox5 Negative_regulation of Localization of Ptafr 1 0.01 0.35 0.24 97.20
113 INT55902 Negative_regulation of Pla2g1b Negative_regulation of Localization of Ptafr 1 0.11 0.35 0.24 97.20
114 INT55903 Negative_regulation of Mthfs Negative_regulation of Localization of Ptafr 1 0.01 0.35 0.24 97.20
115 INT220061 Binding of TRPV1 and TRPA1 1 0.15 1.7 2.69 96.92
116 INT55162 Binding of NFKB1 and RELA 10 0.30 2.82 1.18 96.72
117 INT221383 Tlr4 Positive_regulation of Localization of Ptger2 1 0.00 1.78 0.23 96.72
118 INT132382 Nos2 Positive_regulation of PTGS2 1 0.02 0.1 0.23 96.64
119 INT153993 Myoz1 Regulation of TRPV1 1 0.00 0.46 0.44 96.60
120 INT153994 Regulation of Prkaca Regulation of TRPV1 1 0.02 0.46 0.44 96.60
121 INT153995 Regulation of Myoz1 Regulation of TRPV1 1 0.00 0.46 0.44 96.60
122 INT215290 Siglec1 Negative_regulation of Decr1 1 0.00 0.68 0.41 96.56
123 INT279435 Positive_regulation of Binding of LTA4H and Lts1 1 0.00 0.16 0.08 96.44
124 INT213802 Il4 Regulation of Gene_expression of Insrr 1 0.00 0.76 0.29 96.36
125 INT213808 Il12a Regulation of Gene_expression of Insrr 1 0.00 0.76 0.28 96.00
126 INT279436 Binding of LTA4H and Lts1 1 0.00 0.16 0.08 95.92
127 INT328743 TNF Positive_regulation of Mapk14 1 0.04 1.4 1.21 95.84
128 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65 95.80
129 INT185379 Binding of IRF6 and TLR2 4 0.08 2.88 0.35 95.80
130 INT185385 Binding of TLR2 and TLR4 3 0.27 3.63 0.32 95.80
131 INT121457 KNG1 Positive_regulation of Trpv1 1 0.16 0.91 1.33 95.76
132 INT169570 Binding of ROS1 and TRPV1 3 0.33 3.07 1.89 95.64
133 INT230749 Crp Regulation of Agtr1a 1 0.07 1.33 0.19 95.64
134 INT215282 Siglec1 Regulation of Gene_expression of Ros1 1 0.00 0.55 0.18 95.60
135 INT215292 Siglec1 Regulation of Tlr4 Positive_regulation of Ros1 1 0.00 0.55 0.18 95.60
136 INT215287 Siglec1 Regulation of Ros1 1 0.00 0.55 0.18 95.60
137 INT215291 Siglec1 Regulation of Positive_regulation of Ros1 1 0.00 0.55 0.18 95.60
138 INT215278 Siglec1 Regulation of Tlr4 1 0.01 0.55 0.18 95.60
139 INT215098 Tlr4 Positive_regulation of Localization of Il6 3 0.18 1.18 0.69 95.52
140 INT48714 PTGER2 Negative_regulation of Gene_expression of SERPINE1 1 0.15 0.28 0.38 95.52
141 INT333272 Tlr4 Positive_regulation of Localization of Cxcl1 1 0.36 0.54 0.15 95.52
142 INT333269 Tlr4 Positive_regulation of Localization of PGE 1 0.14 0.54 0.15 95.52
143 INT65014 SOS1 Positive_regulation of Gene_expression of IL6 1 0.45 0.42 0.6 95.36
144 INT132809 TNF Positive_regulation of IL1B 2 0.33 1.26 0.16 95.28
145 INT328742 Il1 Positive_regulation of Mapk14 1 0.01 1.4 1.2 95.20
146 INT178823 TNF Regulation of Il18 1 0.18 3.28 0.41 95.16
147 INT48713 PTGER1 Negative_regulation of Gene_expression of SERPINE1 1 0.02 0.28 0.22 95.12
148 INT182551 Ptgir Negative_regulation of Trpv1 1 0.19 0.7 0.51 95.08
149 INT179938 Negative_regulation of Mapk8 Negative_regulation of TNF 1 0.02 1.09 0.37 95.08
150 INT115261 Gene_expression of Nos2 Positive_regulation of Positive_regulation of Npr1 1 0.05 0.67 0.31 94.84
151 INT215275 Tlr4 Positive_regulation of Gene_expression of Ros1 1 0.01 1.37 0.38 94.80
152 INT65011 IL1B Positive_regulation of PTGER2 4 0.08 0.92 0.82 94.80
153 INT215274 Tlr4 Positive_regulation of Ros1 2 0.02 1.48 0.28 94.80
154 INT182550 Ptger1 Negative_regulation of Trpv1 1 0.35 0.73 1.12 94.80
155 INT122780 Ngf Regulation of Gene_expression of Trpv1 4 0.65 3.74 3.11 94.68
156 INT122775 Gdnf Regulation of Gene_expression of Trpv1 4 0.59 2.72 2.42 94.68
157 INT305851 Polk Positive_regulation of Gene_expression of Tslp 1 0.29 0.9 0.51 94.48
158 INT136368 RYBP Regulation of Localization of Ifng 1 0.00 0.4 0.28 94.24
159 INT195773 Binding of Cd74 and Mif 2 0.25 2.78 0.55 94.20
160 INT278403 Hps5 Positive_regulation of Il1 1 0.04 1.48 0.24 94.12
161 INT103548 Binding of TRPV1 and TRPV3 3 0.37 1.82 2.28 94.00
162 INT307018 MT1JP Positive_regulation of Gene_expression of CD69 1 0.05 0.83 0.29 93.92
163 INT307009 MT1JP Positive_regulation of Gene_expression of LAMP1 1 0.03 0.58 0.26 93.92
164 INT217041 TNF Positive_regulation of Gene_expression of P2RX7 1 0.50 0.81 0.34 93.76
165 INT289246 Il6 Positive_regulation of Gopc 1 0.06 1 0.22 93.76
166 INT236364 CD40LG Positive_regulation of Gene_expression of IL6 1 0.25 1.37 0.72 93.52
167 INT209923 IL17A Negative_regulation of PPARA 1 0.14 2.46 0.99 93.36
168 INT254356 Binding of IFNG and IL1B 1 0.00 1.87 0.51 93.24
169 INT254357 Binding of IFNA1 and IL1B 1 0.00 1.88 0.51 93.24
170 INT140660 Phax Negative_regulation of Trpv1 2 0.08 0.58 0.84 93.20
171 INT195774 Binding of MIF and Cd74 1 0.02 1.15 0.46 93.04
172 INT204792 Tnbs1 Positive_regulation of Transcription of Il10 1 0.09 1.2 0.32 93.00
173 INT215279 Siglec1 Regulation of Rac2 1 0.01 0.74 0.27 92.96
174 INT102690 IL1B Positive_regulation of ITGAL 1 0.05 0.87 0.99 92.56
175 INT215286 Siglec1 Negative_regulation of Gene_expression of Ros1 1 0.00 2.76 0.25 92.56
176 INT342406 AAVS1 Positive_regulation of Icam1 1 0.26 0.19 0.11 92.56
177 INT348380 Binding of Fdps and Lpar5 1 0.07 1.45 1.25 92.32
178 INT348396 Binding of LPAR5 and Fdps 1 0.07 0.81 0.69 92.32
179 INT88279 Ngf Positive_regulation of Ntrk1 5 0.76 3.06 5.23 92.28
180 INT73538 Ngf Positive_regulation of Ngfr 2 0.41 1.05 0.85 92.28
181 INT201740 Positive_regulation of Ngf Positive_regulation of Nfkb1 1 0.01 1.07 0.51 92.28
182 INT201727 Ngf Positive_regulation of Nfkb1 1 0.01 1 0.48 92.28
183 INT153728 RYBP Positive_regulation of Gpt 3 0.03 2.01 2.36 92.28
184 INT215289 Siglec1 Regulation of Cyba 1 0.01 0.74 0.26 92.24
185 INT334136 Binding of IFNA1 and Acsm3 1 0.01 4.52 2.19 92.16
186 INT342405 AAVS1 Positive_regulation of Syp 1 0.05 0.19 0.11 92.12
187 INT215276 Gene_expression of Mpz Positive_regulation of Gene_expression of Ros1 1 0.01 0.4 0.05 91.96
188 INT215281 Mpz Positive_regulation of Gene_expression of Ros1 2 0.01 1.01 0.05 91.96
189 INT215288 Gene_expression of Tlr4 Positive_regulation of Gene_expression of Ros1 1 0.01 0.4 0.05 91.96
190 INT327995 Positive_regulation of TRPV1 Positive_regulation of Tnfrsf1a 1 0.16 0.63 0.46 91.92
191 INT262577 Localization of Ngf Positive_regulation of Positive_regulation of Mapk14 1 0.05 0.92 0.75 91.84
192 INT171297 TNF Positive_regulation of Localization of CCL5 1 0.17 0.66 0.07 91.60
193 INT171284 TNF Positive_regulation of Localization of CXCL10 1 0.09 0.66 0.07 91.60
194 INT145163 Tlr4 Positive_regulation of Localization of Nsfl1c 1 0.02 0.43 0.94 91.56
195 INT285911 Binding of TLR4 and Cd14 1 0.05 1.13 0.51 91.52
196 INT215280 Siglec1 Regulation of Cybb 1 0.01 0.74 0.26 91.52
197 INT303124 Binding of Fas and Tnfrsf10b 1 0.09 1.03 0.08 91.44
198 INT210225 Ptpn2 Positive_regulation of Gene_expression of Ifng 1 0.15 1.44 0.42 91.16
199 INT342979 HCL1 Positive_regulation of TRPV1 Positive_regulation of Localization of SFTPA1 1 0.00 0.54 1.31 91.12
200 INT292556 Binding of F2RL1 and TLR4 1 0.05 0.52 0.22 91.12

Single Events

The table below shows the top 200 pain related interactions that have been reported for Inflammatory mediators. They are ordered first by their pain relevance and then by number of times they were reported in Inflammatory mediators. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 100.00
2 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 100.00
3 INT6852 Localization of TNF 883 0.81 705.95 270.84 100.00
4 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 100.00
5 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 100.00
6 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 100.00
7 INT82448 Gene_expression of S100a8 246 0.77 236.72 84.02 100.00
8 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 100.00
9 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 100.00
10 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 100.00
11 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 100.00
12 INT48953 Positive_regulation of Nos2 486 0.70 239.85 131.87 100.00
13 INT66280 Gene_expression of Nos2 534 0.78 330.78 157.07 100.00
14 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1 100.00
15 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 100.00
16 INT12339 Localization of IL8 437 0.81 251.87 117.39 100.00
17 INT144391 Gene_expression of RETN 42 0.75 40.48 10.47 100.00
18 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 100.00
19 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 100.00
20 INT11937 Localization of Il6 228 0.81 139.83 64.39 100.00
21 INT16573 Regulation of Cl 18 0.07 8.69 6.03 100.00
22 INT77435 Positive_regulation of Nos2 343 0.70 208.49 91.43 100.00
23 INT19472 Gene_expression of Il1 554 0.76 419.75 175.35 100.00
24 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 100.00
25 INT12082 Localization of IL6 365 0.81 241.78 105.78 100.00
26 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59 100.00
27 INT39565 Gene_expression of Ptger2 424 0.75 229.28 72.68 100.00
28 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08 100.00
29 INT1760 Gene_expression of PTGER2 524 0.57 226.94 96.4 100.00
30 INT10506 Gene_expression of PTAFR 86 0.76 37.57 28.58 100.00
31 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58 100.00
32 INT56291 Gene_expression of Ros1 503 0.63 274.12 81.5 100.00
33 INT97596 Localization of S100a8 94 0.78 90.69 40.41 100.00
34 INT131808 Localization of Apex1 2 0.16 13.46 4.61 100.00
35 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62 100.00
36 INT52800 Negative_regulation of Gene_expression of Tnf 142 0.59 92.27 55.47 100.00
37 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 100.00
38 INT10166 Localization of Tnf 237 0.81 153.95 88.64 100.00
39 INT48408 Gene_expression of ICAM1 494 0.78 340.08 88.6 100.00
40 INT73502 Positive_regulation of IL10 154 0.69 124.87 43.5 100.00
41 INT5680 Gene_expression of Ngf 530 0.78 264.29 310.56 100.00
42 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 100.00
43 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 100.00
44 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02 100.00
45 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54 100.00
46 INT3950 Gene_expression of Ptger2 293 0.77 122.28 62.42 100.00
47 INT9660 Regulation of TNF 363 0.62 312.94 139.99 100.00
48 INT52722 Localization of RETNLB 54 0.38 48.63 27.98 100.00
49 INT65889 Gene_expression of RETNLB 73 0.34 60.98 38.3 100.00
50 INT19775 Localization of Il1 183 0.78 145.5 50.91 100.00
51 INT96937 Gene_expression of Mmp9 191 0.75 150.3 56.01 100.00
52 INT10565 Gene_expression of MRXS5 94 0.53 37.35 19.08 100.00
53 INT10837 Positive_regulation of Gene_expression of IL8 294 0.70 190.08 70.34 100.00
54 INT27096 Positive_regulation of Nfkb1 325 0.70 195.11 109.06 100.00
55 INT19511 Localization of Il6 212 0.81 118.17 67.67 100.00
56 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18 100.00
57 INT65054 Positive_regulation of Nfkb1 285 0.70 149.33 126.73 100.00
58 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9 100.00
59 INT1759 Gene_expression of TIMP1 267 0.77 133.87 59.29 100.00
60 INT6849 Localization of IL1B 229 0.81 112.56 69.63 100.00
61 INT49993 Positive_regulation of Gene_expression of Il6 149 0.70 88.07 53.78 100.00
62 INT1765 Positive_regulation of Gene_expression of PTGER2 140 0.51 68.68 27 100.00
63 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 100.00
64 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 100.00
65 INT135411 Gene_expression of Il23a 76 0.72 72.87 26.15 100.00
66 INT20210 Localization of Ngf 69 0.79 46.22 38.57 100.00
67 INT12720 Positive_regulation of Il1 246 0.70 195.97 72.05 100.00
68 INT11491 Positive_regulation of KNG1 128 0.67 60.41 58.74 100.00
69 INT48244 Gene_expression of Il4 172 0.76 132.38 73.42 100.00
70 INT66753 Negative_regulation of Positive_regulation of Tnf 45 0.59 35.28 22.33 100.00
71 INT48895 Gene_expression of Il10 333 0.78 221.2 138.52 100.00
72 INT9655 Regulation of Il6 98 0.62 70.92 31.95 100.00
73 INT92837 Negative_regulation of Gene_expression of Nos2 116 0.59 59.67 31.82 100.00
74 INT11377 Positive_regulation of Ngf 331 0.70 206.5 238 100.00
75 INT212125 Regulation of Gene_expression of Cl 2 0.06 1.88 1.05 100.00
76 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35 100.00
77 INT77434 Positive_regulation of Gene_expression of Nos2 151 0.69 96.76 38.94 100.00
78 INT24326 Gene_expression of Ngf 346 0.78 218.67 184.71 100.00
79 INT8357 Gene_expression of KNG1 153 0.75 77.26 68.66 100.00
80 INT5307 Regulation of Tnf 87 0.62 78.71 43.4 100.00
81 INT55344 Gene_expression of Ros1 396 0.54 217.64 59.98 100.00
82 INT83953 Gene_expression of Cxcl2 140 0.75 113.07 43.65 100.00
83 INT78057 Localization of Tlr4 140 0.77 67.75 21.72 100.00
84 INT25396 Localization of Ptger2 83 0.78 46.81 14.81 100.00
85 INT171011 Localization of RETN 12 0.73 19.2 4.64 100.00
86 INT85943 Negative_regulation of Nos2 161 0.59 108.56 42.65 100.00
87 INT52801 Regulation of Gene_expression of Tnf 55 0.62 48.74 26.59 100.00
88 INT7134 Localization of KNG1 127 0.79 65.73 67.97 100.00
89 INT147792 Gene_expression of COPD 230 0.70 287.13 24.1 100.00
90 INT6486 Positive_regulation of Tnf 168 0.70 123.47 66.05 100.00
91 INT187489 Localization of ATIC 1 0.07 4.03 1.81 100.00
92 INT56290 Negative_regulation of Gene_expression of Il6 79 0.59 47.98 31.07 100.00
93 INT5822 Gene_expression of Ltb4r1 51 0.76 37.43 7.2 100.00
94 INT68976 Positive_regulation of Gene_expression of Mmp9 34 0.42 28.21 11.28 100.00
95 INT67614 Positive_regulation of PPARA 438 0.68 293.28 63.61 100.00
96 INT89661 Gene_expression of Hrec 102 0.21 69.91 39.57 100.00
97 INT22454 Regulation of Crp 213 0.62 160.67 49.24 100.00
98 INT113606 Positive_regulation of Gene_expression of Mmp9 46 0.64 44 15.07 100.00
99 INT55343 Localization of Ros1 39 0.60 34.51 12.5 100.00
100 INT87239 Localization of Il12a 51 0.75 31.95 12.05 100.00
101 INT82254 Positive_regulation of Gene_expression of Cxcl1 17 0.69 9.95 6.47 100.00
102 INT68975 Gene_expression of Mmp9 111 0.78 79.57 38.55 100.00
103 INT35406 Localization of Tnf 94 0.81 64.63 31.65 100.00
104 INT53083 Gene_expression of Ptgs2 153 0.78 90.04 50.39 100.00
105 INT66026 Gene_expression of Cxcl1 74 0.78 31.87 23.37 100.00
106 INT64499 Positive_regulation of IRF6 123 0.49 52.73 27.51 100.00
107 INT9233 Negative_regulation of Gene_expression of IL1B 114 0.59 56.99 41.82 100.00
108 INT45913 Positive_regulation of Gene_expression of Apcs 3 0.40 5.27 0.83 100.00
109 INT10706 Regulation of Il6 150 0.62 93.23 62.34 100.00
110 INT11939 Negative_regulation of Il6 138 0.59 87.46 41.24 100.00
111 INT16254 Positive_regulation of Gene_expression of Ngf 144 0.70 80.61 82.08 100.00
112 INT50230 Positive_regulation of Localization of IL6 105 0.70 69.21 29.52 100.00
113 INT145426 Positive_regulation of Ros1 185 0.56 106.76 27.21 100.00
114 INT234717 Regulation of Cxcl1 10 0.41 6.14 2.9 100.00
115 INT121599 Negative_regulation of Gene_expression of RETNLB 7 0.21 9.28 8.8 100.00
116 INT61257 Gene_expression of Sele 79 0.77 70.97 17.78 100.00
117 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85 100.00
118 INT11318 Gene_expression of Gtf3a 274 0.52 183.82 60.89 100.00
119 INT50957 Negative_regulation of Il6 134 0.59 79.08 42.67 100.00
120 INT138891 Regulation of Gene_expression of Slc12a2 5 0.58 4.83 2.64 100.00
121 INT152730 Positive_regulation of S100a8 48 0.68 47.67 15.4 100.00
122 INT111594 Positive_regulation of Gene_expression of NOSTRIN 20 0.32 8.69 5 100.00
123 INT26501 Positive_regulation of Gene_expression of MMP2 51 0.67 39 15.16 100.00
124 INT9210 Regulation of IL6 166 0.62 125.61 49.95 100.00
125 INT104392 Gene_expression of Cxcl10 113 0.75 106.86 34.12 100.00
126 INT11938 Positive_regulation of Localization of Il6 61 0.70 35.72 18.25 100.00
127 INT5973 Regulation of IL1B 109 0.62 66.6 39.88 100.00
128 INT110767 Localization of Mcpt1 43 0.68 24.3 16.74 100.00
129 INT73670 Gene_expression of Vcam1 128 0.78 123.79 24.96 100.00
130 INT127378 Localization of Mpo 21 0.78 26.36 8.28 100.00
131 INT54358 Localization of Ltb4r1 13 0.34 14.31 2.6 100.00
132 INT253751 Localization of Lif 3 0.73 3.94 1.58 100.00
133 INT96271 Positive_regulation of Gene_expression of Mcpt1 30 0.53 21.34 11.06 100.00
134 INT91817 Positive_regulation of RETNLB 22 0.34 21.4 13.12 100.00
135 INT70048 Positive_regulation of Gene_expression of IL10 90 0.55 71.34 25.66 100.00
136 INT75434 Gene_expression of Il13 27 0.52 26.19 15.4 100.00
137 INT81531 Positive_regulation of Gene_expression of Nfkb1 27 0.69 13.9 11.04 100.00
138 INT3988 Positive_regulation of Gene_expression of IGHE 98 0.68 91.46 9.61 100.00
139 INT8483 Positive_regulation of Positive_regulation of TNF 73 0.67 60.35 22.03 100.00
140 INT104388 Positive_regulation of Gene_expression of Cxcl2 31 0.66 25.68 7.49 100.00
141 INT112003 Localization of ROS1 94 0.73 66.32 12.16 100.00
142 INT81880 Positive_regulation of Gene_expression of Sele 30 0.48 27.54 7.05 100.00
143 INT117465 Positive_regulation of Localization of S100a8 8 0.42 10.04 3.89 100.00
144 INT6474 Positive_regulation of Gene_expression of IL1RN 34 0.69 21.87 10.99 100.00
145 INT1214 Gene_expression of PGE 70 0.72 29.07 16.22 100.00
146 INT51576 Positive_regulation of Cxcl1 42 0.69 20.12 16.41 100.00
147 INT113602 Positive_regulation of Gene_expression of Ccl2 48 0.70 48.71 17.85 100.00
148 INT21582 Regulation of Gene_expression of TIMP1 20 0.61 12.39 4.77 100.00
149 INT153634 Regulation of REST 4 0.48 1.42 0.54 100.00
150 INT54701 Localization of Ptafr 19 0.49 18.68 3.82 100.00
151 INT52692 Gene_expression of Ptgs2 160 0.78 85.06 55.73 100.00
152 INT9383 Localization of TRPV1 98 0.81 33.23 46.24 100.00
153 INT16794 Binding of App 103 0.48 64.87 19.79 100.00
154 INT92682 Positive_regulation of Gene_expression of Ctgf 17 0.69 12.16 4.51 100.00
155 INT332801 Regulation of Ccl20 5 0.21 1.89 0.48 100.00
156 INT100144 Negative_regulation of Positive_regulation of PPARA 17 0.49 12.71 2.68 100.00
157 INT156874 Positive_regulation of Gene_expression of S100a8 26 0.49 32.8 8.99 100.00
158 INT64113 Positive_regulation of Gene_expression of NOS1 110 0.60 71.03 29.72 100.00
159 INT5864 Localization of IL36RN 19 0.44 14.5 6.87 100.00
160 INT21793 Positive_regulation of Ngf 154 0.70 94.78 85.27 100.00
161 INT4860 Positive_regulation of CALCA 148 0.00 73.35 97.61 100.00
162 INT66857 Regulation of CCL2 39 0.53 28.55 18.35 100.00
163 INT16210 Localization of LTB4R 14 0.54 6.58 6.19 100.00
164 INT10505 Gene_expression of Ptafr 18 0.62 10.7 6.83 100.00
165 INT6480 Positive_regulation of IL1RN 59 0.69 33.7 16.66 100.00
166 INT2144 Localization of COL7A1 36 0.74 20.92 4.67 100.00
167 INT38731 Localization of Trpv1 138 0.81 52.73 90.49 100.00
168 INT4190 Localization of PGE 19 0.60 4.97 7.9 100.00
169 INT92129 Positive_regulation of Gene_expression of F3 13 0.08 12.13 2.02 100.00
170 INT46188 Regulation of Localization of Ptgfr 2 0.15 0.52 0.53 100.00
171 INT9191 Localization of EDN1 94 0.81 57.01 14.78 100.00
172 INT16159 Regulation of Ltc4s 11 0.38 2.52 3.21 100.00
173 INT112530 Localization of Ptgs2 13 0.70 7.77 5.86 100.00
174 INT154093 Positive_regulation of Gene_expression of Eae1 23 0.20 26.08 5.84 100.00
175 INT171767 Positive_regulation of Gene_expression of MMP15 4 0.38 4.48 0.59 100.00
176 INT11893 Positive_regulation of Ptger2 96 0.69 31.49 21.92 100.00
177 INT12084 Regulation of Localization of IL6 36 0.61 20.32 12.34 100.00
178 INT49441 Negative_regulation of Cpox 494 0.59 303.22 177.46 100.00
179 INT61949 Regulation of Nos2 74 0.58 34.08 16.7 100.00
180 INT5948 Regulation of Il1b 44 0.60 22.8 25.4 100.00
181 INT117518 Transcription of Ccl2 12 0.68 11.12 3.61 100.00
182 INT75832 Positive_regulation of Positive_regulation of IL8 30 0.70 20.77 6.05 100.00
183 INT23435 Positive_regulation of NGF 54 0.70 32.41 30.11 100.00
184 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 100.00
185 INT87212 Negative_regulation of Positive_regulation of Nfkb1 74 0.57 38.21 28.31 100.00
186 INT55255 Positive_regulation of Localization of Il6 48 0.69 24.88 12.76 100.00
187 INT25076 Negative_regulation of Gene_expression of Il1 41 0.52 30.58 13.85 100.00
188 INT87823 Positive_regulation of Cxcl2 51 0.66 35.47 14.79 100.00
189 INT19078 Binding of Ngf 78 0.48 31.03 44.33 100.00
190 INT7561 Positive_regulation of gr 70 0.57 31.92 20.22 100.00
191 INT71381 Localization of Nos1 33 0.79 11.46 8.05 100.00
192 INT63419 Gene_expression of PTGES 109 0.77 40.83 23.67 100.00
193 INT187095 Negative_regulation of Positive_regulation of Il1 8 0.14 6.17 1.82 100.00
194 INT48201 Localization of Tgfb1 27 0.59 13.65 5.54 100.00
195 INT61039 Localization of Ltb4r 7 0.59 9.51 2.44 100.00
196 INT144646 Positive_regulation of Rela 53 0.67 27.78 13.2 100.00
197 INT160828 Regulation of Gene_expression of Ros1 29 0.21 13.97 3.75 100.00
198 INT89594 Gene_expression of Ccl5 44 0.54 24.08 18.62 100.00
199 INT88544 Gene_expression of MMRN1 102 0.75 68.8 14.55 100.00
200 INT11957 Negative_regulation of LPA 52 0.59 39.09 6.84 100.00
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