P:Inflammatory stimuli

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Pain Term
Category Family
Synonyms Inflammatory Stimulus
Pain Specific No
Documents 448
Hot Single Events 200
Hot Interactions 87

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Inflammatory stimuli. They are ordered first by their pain relevance and then by number of times they were reported for Inflammatory stimuli. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT263454 Negative_regulation of IRF6 Positive_regulation of TNF 1 0.12 0.49 0.59 100.00
2 INT217042 IRF6 Positive_regulation of TNF 4 0.27 3.03 1.95 100.00
3 INT137207 Tnf Positive_regulation of Nfkb1 3 0.23 2.69 1.71 100.00
4 INT184114 Tlr4 Positive_regulation of Socs3 2 0.65 1.14 0.83 100.00
5 INT253994 Cyp3a23/3a1 Positive_regulation of Localization of Mif 1 0.09 0.96 0.69 100.00
6 INT177899 Crp Positive_regulation of Positive_regulation of Crp 1 0.01 1.69 0.6 100.00
7 INT54570 Positive_regulation of NFKB1 Positive_regulation of Gene_expression of IL8 1 0.24 0.77 0.35 100.00
8 INT117517 PROC Positive_regulation of PTGS2 1 0.01 0.61 0.19 100.00
9 INT199109 Binding of Akt1 and Arhgdia 1 0.02 2.73 0.87 99.96
10 INT207141 Tlr4 Positive_regulation of Positive_regulation of Pawr 1 0.05 0.79 0.46 99.82
11 INT238384 Tlr4 Positive_regulation of Prkca 1 0.06 0.81 0.4 99.82
12 INT190524 Ros1 Positive_regulation of Nfkb1 3 0.02 4.24 2.06 99.70
13 INT175986 Ros1 Positive_regulation of Gtf3a 2 0.01 4.75 1.71 99.70
14 INT352465 Dusp1 Negative_regulation of Gene_expression of Mapk14 1 0.03 1.09 0.92 99.36
15 INT352456 Dusp1 Negative_regulation of Mapk14 1 0.03 1.31 1.03 99.08
16 INT352444 Dusp1 Negative_regulation of Phosphorylation of Mapk14 1 0.03 1.09 0.91 99.08
17 INT266489 Dcps Positive_regulation of Gene_expression of Nos2 1 0.06 3.43 0.63 99.08
18 INT205713 Positive_regulation of P2rx7 Positive_regulation of Gene_expression of IL8 1 0.03 0.77 0.33 98.58
19 INT155359 CNR2 Negative_regulation of CNR1 1 0.46 0.5 0.54 98.08
20 INT94493 Avp Positive_regulation of Gene_expression of Ifng 1 0.05 1.73 0.97 97.88
21 INT355687 Art2b Positive_regulation of Gene_expression of Mc3r 1 0.02 1.01 0.48 97.32
22 INT291256 INS Negative_regulation of Positive_regulation of Mdk 1 0.01 1.65 0.39 96.76
23 INT94501 Il2 Positive_regulation of Gene_expression of Ifng 1 0.03 1.63 0.92 94.88
24 INT209931 IL1B Positive_regulation of PPARA 1 0.32 0.62 0.31 94.48
25 INT156632 Prkaca Regulation of Scn10a 1 0.13 0.67 0.3 94.24
26 INT352462 Gse1 Positive_regulation of Gene_expression of Tnc 1 0.05 0.75 0.64 93.96
27 INT350814 Negative_regulation of TNF Positive_regulation of Gene_expression of Cpox 1 0.06 1.33 0.37 93.84
28 INT350816 TNF Positive_regulation of Gene_expression of Cpox 1 0.05 1.33 0.37 93.84
29 INT354820 Creb1 Negative_regulation of Transcription of Cpox 1 0.03 0.59 0.38 93.76
30 INT327328 Binding of Hnrnpd and Elavl1 1 0.06 0.74 0.3 93.68
31 INT327316 Binding of Elavl1 and Khsrp 1 0.12 0.36 0.14 93.68
32 INT81920 Binding of IL1B and NFKB1 1 0.04 1.54 1.85 93.48
33 INT81914 Binding of HSF1 and NFKB1 1 0.05 1.54 1.85 93.48
34 INT81919 Binding of HSF1 and IL1B 1 0.42 0.77 0.93 92.84
35 INT291257 Map3k8 Regulation of Positive_regulation of MAPK1 1 0.09 1 0.28 92.68
36 INT291239 Map3k8 Regulation of Positive_regulation of Mdk 1 0.08 0.53 0.11 92.68
37 INT291377 Binding of CX3CR1 and Cx3cl1 2 0.36 3.57 1.02 92.64
38 INT322011 BSG Regulation of P2RX7 1 0.00 0.48 0.21 92.52
39 INT193218 Binding of PTGER1 and PTGER2 3 0.12 2.31 0.66 92.32
40 INT193217 Binding of PTGER2 and PTGER3 2 0.10 1.31 0.43 92.32
41 INT199107 Binding of Akt1 and Ncf2 1 0.04 0.09 0.05 92.00
42 INT270827 P2rx7 Positive_regulation of Localization of Panx1 1 0.41 0.18 0.13 91.88
43 INT199311 Ptger2 Regulation of Cpox 1 0.01 0.73 0.07 91.44
44 INT294115 IDO1 Positive_regulation of PTGER2 1 0.02 0.36 0.31 90.80
45 INT294117 HGF Positive_regulation of PTGER2 1 0.02 0.36 0.31 90.80
46 INT327340 Binding of TNF and Hnrnpd 1 0.03 1.02 0.25 90.72
47 INT327300 Binding of Hnrnpd and Myc 1 0.12 1.02 0.25 90.32
48 INT209066 Slc11a1 Positive_regulation of Binding of TNF 1 0.01 1.11 0.24 90.00
49 INT291251 Map3k8 Regulation of Gene_expression of MAPK8 1 0.05 0.52 0.11 88.60
50 INT291260 Map3k8 Regulation of Gene_expression of MAPK14 1 0.07 0.52 0.11 88.60
51 INT53951 Negative_regulation of Trib3 Negative_regulation of Gene_expression of Ptgs1 1 0.01 0.43 0.26 88.56
52 INT343569 Negative_regulation of Synm Positive_regulation of Gpt 1 0.01 0.96 0.29 88.52
53 INT343571 Synm Positive_regulation of ALPP 1 0.01 1.28 0.28 88.52
54 INT343570 Synm Positive_regulation of Gpt 1 0.01 1.28 0.28 88.52
55 INT343573 Synm Positive_regulation of SLC17A5 1 0.17 1.28 0.28 88.52
56 INT174468 IL7 Positive_regulation of Gene_expression of IL4 1 0.40 1.88 1.02 88.32
57 INT188522 Binding of Ptger2 and Ugt1a7c 1 0.00 0.63 0.36 88.20
58 INT222522 Il1a Positive_regulation of Gene_expression of Il6 2 0.06 1.79 2.79 87.60
59 INT327310 Binding of Ccnd1 and Elavl1 1 0.04 0.38 0.16 87.40
60 INT291240 Map3k8 Positive_regulation of Positive_regulation of Mapk1 1 0.16 0.72 0.32 87.04
61 INT291241 Map3k8 Positive_regulation of Gene_expression of Mapk1 1 0.17 0.72 0.32 87.04
62 INT327325 Binding of Hnrnpd and Ccnd1 1 0.03 0.38 0.16 86.68
63 INT195769 MIF Regulation of Gene_expression of TP53I11 1 0.19 1.24 0.47 86.56
64 INT204087 IL1B Positive_regulation of Gene_expression of LEP 1 0.09 2.6 0.54 86.48
65 INT346234 MAP2K6 Positive_regulation of MAPK14 1 0.44 1.65 0.77 86.04
66 INT346237 MAP2K6 Positive_regulation of MAP2K3 1 0.49 1 0.44 86.04
67 INT199103 Akt1 Positive_regulation of Ncf2 1 0.05 0.09 0.04 85.84
68 INT285943 IL17A Positive_regulation of Localization of IL6 3 0.20 2.02 0.65 85.80
69 INT167155 FPR1 Positive_regulation of Phosphorylation of MAPK1 1 0.18 0.17 0.33 85.64
70 INT264385 Binding of IL1B and MMP1 1 0.24 0.09 0.13 85.32
71 INT270835 Positive_regulation of P2rx7 Positive_regulation of Localization of DPEP1 1 0.04 0.08 0.07 85.24
72 INT264399 Binding of IL1B and MMP13 1 0.39 0.08 0.13 84.92
73 INT190174 TNF Positive_regulation of MMP12 1 0.27 0.08 0.74 84.48
74 INT327312 Positive_regulation of Ttpa Negative_regulation of Elavl1 1 0.03 0.45 0.19 83.60
75 INT327317 Ttpa Negative_regulation of Elavl1 1 0.02 0.45 0.19 83.20
76 INT327327 Ttpa Negative_regulation of Il3 1 0.01 0.4 0.17 83.20
77 INT190167 Binding of JUN and MMP12 1 0.26 0.82 2.76 83.12
78 INT190182 JUN Positive_regulation of MMP12 1 0.34 0.08 0.8 83.12
79 INT291262 Positive_regulation of INS Positive_regulation of Mapk1 1 0.03 1.78 0.58 82.96
80 INT291258 INS Positive_regulation of Mapk1 1 0.04 1.77 0.58 82.96
81 INT291249 Map3k8 Positive_regulation of INS Positive_regulation of AKT1 1 0.01 0.76 0.29 82.96
82 INT291202 Positive_regulation of INS Positive_regulation of AKT1 1 0.01 0.76 0.29 82.96
83 INT89381 INS Positive_regulation of AKT1 6 0.43 3.06 0.33 82.96
84 INT327333 Binding of TNF and Fxr1 1 0.06 3.74 0.48 82.84
85 INT280951 Tlr4 Positive_regulation of Localization of S100a8 1 0.01 1.09 0.69 82.60
86 INT69163 Tlr4 Positive_regulation of Ptgs1 1 0.02 0.08 0.44 82.00
87 INT49044 Tac2 Regulation of Gene_expression of Tacr3 1 0.17 0.32 0.76 81.36
88 INT254120 Aliq1 Positive_regulation of Tbce 1 0.00 0.68 0.43 79.76
89 INT313741 Negative_regulation of NOS1 Positive_regulation of Sdcbp 1 0.00 0.78 0.09 79.24
90 INT45423 Avp Positive_regulation of Localization of Prl 4 0.67 1.37 1.98 79.08
91 INT238383 Tlr4 Positive_regulation of Ppara 1 0.17 0.41 0.23 78.92
92 INT284309 Tlr4 Positive_regulation of Mir155 3 0.18 0.51 0.11 78.28
93 INT303948 LEPR Positive_regulation of PIK3CG 1 0.02 0.22 0.28 77.04
94 INT270829 P2rx7 Positive_regulation of Panx1 1 0.66 0.08 0.08 76.88
95 INT327315 S100a8 Negative_regulation of Binding of Khsrp 1 0.01 0.55 0.21 76.80
96 INT195773 Binding of Cd74 and Mif 2 0.25 2.78 0.55 76.72
97 INT195774 Binding of MIF and Cd74 1 0.02 1.15 0.46 76.72
98 INT303949 LEPR Positive_regulation of SOAT1 1 0.01 0.22 0.28 76.56
99 INT353332 Binding of F2r and Pawr 1 0.18 0.67 0.39 76.32
100 INT261048 CHR Positive_regulation of CA2 1 0.03 0.21 0.21 76.16
101 INT195708 SERPINC1 Negative_regulation of TNF 1 0.17 0.66 0.15 75.88
102 INT199108 Akt1 Negative_regulation of Gene_expression of Arhgdia 1 0.02 0.07 0.04 75.20
103 INT327320 Positive_regulation of Binding of Elavl1 and Nos2 1 0.06 0.6 0.24 74.60
104 INT327321 Binding of Elavl1 and Nos2 1 0.05 0.6 0.24 74.28
105 INT346238 PREP Negative_regulation of IL1B 1 0.04 0.99 0.41 73.92
106 INT353338 F2r Positive_regulation of Localization of Mif 1 0.68 1.25 1.16 73.52
107 INT190169 Regulation of JUN Positive_regulation of Localization of MMP12 1 0.30 0.07 0.74 73.36
108 INT209934 IL1B Positive_regulation of MAPK8 1 0.06 0.37 0.19 72.76
109 INT209928 IL1B Positive_regulation of MAPK14 2 0.15 1.69 0.87 72.56
110 INT262194 Rhof Positive_regulation of Nr1i2 1 0.15 0.64 0.27 72.20
111 INT262164 Positive_regulation of Rhof Positive_regulation of Nr1i2 1 0.11 0.65 0.27 72.20
112 INT209930 IL1B Positive_regulation of MAPK1 1 0.13 0.37 0.18 72.20
113 INT139357 Nr1h2 Regulation of Gene_expression of Ptges 1 0.07 0.5 0.25 71.92
114 INT221417 IL12A Positive_regulation of Binding of IFN1@ 1 0.14 0.98 0.33 71.80
115 INT224730 Fgf2 Positive_regulation of Gm2458 1 0.01 0.39 0.17 71.68
116 INT297314 Binding of Bsg and Sele 1 0.11 1.37 0.37 71.60
117 INT224732 VEGFA Positive_regulation of Gm2458 1 0.02 0.39 0.17 70.88
118 INT217041 TNF Positive_regulation of Gene_expression of P2RX7 1 0.50 0.81 0.34 70.48
119 INT270834 CBX1 Negative_regulation of Transcription of Panx1 1 0.06 0.13 0.1 70.12
120 INT270837 Negative_regulation of Panx1 Negative_regulation of Transcription of CBX1 1 0.07 0.13 0.1 70.12
121 INT107951 Pax3 Positive_regulation of Tac1 1 0.11 1.21 0.95 68.72
122 INT266419 HMGB1 Positive_regulation of Ager 1 0.01 1.37 0.37 68.72
123 INT266375 S100b Positive_regulation of Ager 1 0.02 1.8 0.31 68.72
124 INT266385 S100a6 Positive_regulation of Ager 1 0.01 0.84 0.1 68.72
125 INT266373 Itgam Positive_regulation of Ager 1 0.01 0.84 0.1 68.72
126 INT306018 Binding of Tlr4 and Tlr9 1 0.15 0.92 0.27 68.28
127 INT185322 TNF Positive_regulation of Gene_expression of Tlr4 1 0.01 0.36 0.31 67.12
128 INT207151 PLA2G6 Positive_regulation of Localization of F2rl1 1 0.16 0.73 0.18 67.12
129 INT207147 Pla2g1b Positive_regulation of Localization of F2rl1 1 0.03 0.73 0.18 67.12
130 INT185319 Il6 Positive_regulation of Gene_expression of Tlr4 1 0.11 0.36 0.31 66.48
131 INT180984 IRF6 Positive_regulation of Localization of IL8 7 0.11 2.13 3.47 66.24
132 INT266413 Positive_regulation of Binding of HMGB1 and Col4a1 1 0.02 1.05 0.14 65.64
133 INT207391 Il17a Positive_regulation of Gene_expression of Tnfsf11 2 0.05 1.19 0.77 65.60
134 INT266411 Binding of HMGB1 and Col4a1 1 0.01 1.05 0.14 65.20
135 INT303994 Il6 Positive_regulation of JAK2 1 0.03 0.41 0.37 64.12
136 INT303982 Il6 Positive_regulation of STAT3 1 0.03 0.41 0.37 64.12
137 INT254000 Regulation of Binding of Cxcr4 and Mif 1 0.29 0.56 0.27 63.88
138 INT221416 Binding of IL1B and Positive_regulation of NFKB2 1 0.02 0.88 0.23 63.84
139 INT254001 Binding of Cxcr4 and Mif 1 0.52 14.17 7.18 63.56
140 INT209919 SFTPA2 Negative_regulation of IL1B Negative_regulation of PPARA 1 0.00 0.17 0.09 61.36
141 INT264397 MMP9 Regulation of Positive_regulation of MMP13 1 0.20 0.06 0.12 60.60
142 INT264389 MMP14 Regulation of Positive_regulation of MMP13 1 0.31 0.06 0.12 60.60
143 INT264384 MMP3 Regulation of Positive_regulation of MMP1 1 0.13 0.06 0.12 60.60
144 INT264381 MMP3 Regulation of Positive_regulation of MMP13 1 0.21 0.06 0.12 60.60
145 INT264395 MMP9 Regulation of Positive_regulation of MMP1 1 0.13 0.06 0.12 60.60
146 INT264411 MMP14 Regulation of Positive_regulation of MMP1 1 0.20 0.06 0.12 60.60
147 INT209923 IL17A Negative_regulation of PPARA 1 0.14 2.46 0.99 60.08
148 INT253760 Hmgb1 Positive_regulation of Gene_expression of Apex1 1 0.10 3.53 0.58 59.96
149 INT253761 Hmgb1 Positive_regulation of Gene_expression of Gopc 1 0.03 0.73 0.12 59.96
150 INT182096 Positive_regulation of Binding of Il6 and Il1 2 0.09 4.26 1.31 59.68
151 INT182100 Positive_regulation of Binding of TNF and Il6 1 0.03 0.66 0.41 59.68
152 INT182097 Binding of Il6 and Il1 4 0.07 4.67 1.55 59.36
153 INT182021 Binding of TNF and Il6 2 0.04 0.74 0.53 59.36
154 INT81916 HSF1 Positive_regulation of FOS 1 0.76 0.66 0.59 59.04
155 INT81918 HSF1 Negative_regulation of FOS 1 0.64 0.66 0.59 59.04
156 INT353331 Elane Positive_regulation of F2r 1 0.08 0.78 0.44 58.24
157 INT81915 HSF1 Negative_regulation of IL1B 1 0.51 0.65 0.59 58.16
158 INT81917 HSF1 Positive_regulation of IL1B 1 0.41 0.65 0.59 58.16
159 INT349331 Tlr4 Positive_regulation of Positive_regulation of Il12a 1 0.01 0.19 0.08 58.16
160 INT264400 MMP9 Regulation of MMP14 1 0.08 0.06 0.11 57.72
161 INT264398 MMP9 Regulation of MMP2 1 0.07 0.06 0.11 57.72
162 INT264388 MMP9 Regulation of MMP3 1 0.06 0.06 0.11 57.72
163 INT209924 IL1B Negative_regulation of PPARA 1 0.20 4.38 2.17 57.20
164 INT264409 MMP2 Regulation of MMP3 1 0.07 0.06 0.11 57.20
165 INT264406 MMP3 Regulation of MMP14 1 0.09 0.06 0.11 57.20
166 INT264402 MMP2 Regulation of MMP14 1 0.10 0.06 0.11 57.20
167 INT264390 MMP3 Regulation of MMP2 1 0.07 0.06 0.11 57.20
168 INT207149 Binding of F2r and Par2 1 0.17 1.64 0.92 57.12
169 INT328743 TNF Positive_regulation of Mapk14 1 0.04 1.4 1.21 56.48
170 INT328742 Il1 Positive_regulation of Mapk14 1 0.01 1.4 1.2 56.48
171 INT188524 Il1a Positive_regulation of Ptges 1 0.00 0.31 0.28 55.64
172 INT342882 Positive_regulation of Ephb1 Regulation of Gene_expression of Pdyn 1 0.01 0.36 0.33 54.96
173 INT221386 Tlr4 Positive_regulation of Gene_expression of IL8 6 0.14 3.53 0.9 54.92
174 INT303983 Lep Positive_regulation of CXCL10 1 0.06 0.31 0.29 54.88
175 INT303998 Lep Positive_regulation of Localization of IL1RAPL1 1 0.04 0.31 0.29 54.88
176 INT303995 Lep Positive_regulation of PSME1 1 0.09 0.32 0.29 54.88
177 INT237679 IRF6 Positive_regulation of MAPK8 1 0.00 0.56 0.28 54.68
178 INT207116 F2 Positive_regulation of F2r 5 0.12 2.16 1.16 54.32
179 INT207111 F2 Positive_regulation of Pawr 2 0.07 1.38 0.64 54.32
180 INT197777 Pla2g10 Regulation of Pla2g2a 1 0.02 0.61 0.08 53.84
181 INT197776 Pla2g10 Regulation of Pla2g4a 1 0.18 0.61 0.08 53.84
182 INT188521 Binding of Hsp90aa1 and Ptges3 1 0.02 0.61 0.33 53.24
183 INT167154 FPR1 Positive_regulation of ING1 1 0.18 0.18 0.44 52.84
184 INT249090 FOXL1 Regulation of Regulation of ICAM1 1 0.12 1.03 0.37 51.44
185 INT264478 Mapk1 Positive_regulation of Jun 1 0.02 0.12 0.17 51.20
186 INT209932 MAPK8 Positive_regulation of IL1B 1 0.14 0.05 0.03 51.08
187 INT209927 MAPK14 Positive_regulation of IL1B 1 0.13 0.05 0.03 50.76
188 INT238641 Binding of TNF and Ifx 1 0.07 0.86 0.84 50.64
189 INT238642 Binding of TNF and Ada 1 0.03 0.86 0.84 50.64
190 INT61359 TNF Positive_regulation of NFKB1 11 0.63 6.66 3.89 50.00
191 INT61360 Regulation of TNF Positive_regulation of NFKB1 2 0.21 1.34 0.14 50.00
192 INT249111 SAI1 Regulation of Cora1 1 0.00 0.15 0.08 50.00
193 INT103286 Negative_regulation of IRF6 Positive_regulation of NFKB1 1 0.18 0 0 50.00
194 INT103287 IRF6 Positive_regulation of NFKB1 1 0.19 0 0 50.00
195 INT289465 IRF6 Positive_regulation of IL1B 3 0.05 0.9 1.16 49.80
196 INT234608 Socs3 Negative_regulation of SOAT1 1 0.01 0.54 0.39 49.60
197 INT234607 Socs3 Negative_regulation of JAK1 1 0.01 0.54 0.39 49.20
198 INT233514 Tlr4 Positive_regulation of Prokr1 1 0.10 0.45 0.05 48.48
199 INT179502 Binding of Cd14 and Tlr4 29 0.39 13.77 5.73 48.04
200 INT209581 Twist1 Positive_regulation of Gene_expression of VEGFA 6 0.06 7.86 0.16 47.68

Single Events

The table below shows the top 200 pain related interactions that have been reported for Inflammatory stimuli. They are ordered first by their pain relevance and then by number of times they were reported in Inflammatory stimuli. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT64499 Positive_regulation of IRF6 123 0.49 52.73 27.51 100.00
2 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 100.00
3 INT22045 Gene_expression of IRF6 158 0.75 58.07 27.81 100.00
4 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57 100.00
5 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 100.00
6 INT6852 Localization of TNF 883 0.81 705.95 270.84 100.00
7 INT9210 Regulation of IL6 166 0.62 125.61 49.95 100.00
8 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 100.00
9 INT22046 Negative_regulation of IRF6 52 0.43 25.69 14.13 100.00
10 INT82448 Gene_expression of S100a8 246 0.77 236.72 84.02 100.00
11 INT19472 Gene_expression of Il1 554 0.76 419.75 175.35 100.00
12 INT48222 Positive_regulation of Localization of IL8 123 0.59 78.04 37.2 100.00
13 INT97798 Localization of IRF6 86 0.73 33.27 20.94 100.00
14 INT9239 Regulation of Gene_expression of IL6 106 0.61 75.24 36.53 100.00
15 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 100.00
16 INT104392 Gene_expression of Cxcl10 113 0.75 106.86 34.12 100.00
17 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9 100.00
18 INT5591 Regulation of Gene_expression of Fos 425 0.62 129.06 265.78 100.00
19 INT104395 Gene_expression of Cxcl9 83 0.76 73.1 19.79 100.00
20 INT190188 Regulation of Localization of MMP12 1 0.44 0.39 2.8 100.00
21 INT1951 Positive_regulation of Tlr4 345 0.70 176.99 62.42 100.00
22 INT43906 Regulation of Tlr4 71 0.53 35.18 15.49 100.00
23 INT36053 Positive_regulation of Positive_regulation of IL1B 22 0.70 11.41 6.84 100.00
24 INT232234 Positive_regulation of Positive_regulation of Saa 2 0.41 5.59 1.28 100.00
25 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 100.00
26 INT47680 Regulation of Gene_expression of Bdnf 92 0.62 41.61 53.24 100.00
27 INT8881 Regulation of Gene_expression of Tacr1 38 0.61 17.49 27.19 100.00
28 INT47690 Regulation of Bdnf 118 0.62 53.02 64.5 100.00
29 INT4857 Regulation of Tacr1 115 0.62 39.01 84.52 100.00
30 INT95367 Negative_regulation of Positive_regulation of IRF6 7 0.21 3.5 1.34 100.00
31 INT66918 Regulation of HSF1 8 0.43 4.18 0.61 100.00
32 INT36262 Positive_regulation of Tbce 35 0.49 28.79 14.33 100.00
33 INT9660 Regulation of TNF 363 0.62 312.94 139.99 100.00
34 INT1764 Negative_regulation of Gene_expression of PTGER2 81 0.34 34.74 19.45 100.00
35 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99 100.00
36 INT65537 Positive_regulation of Positive_regulation of Nfkb1 52 0.67 30.6 26.35 100.00
37 INT80110 Regulation of Positive_regulation of TNF 34 0.44 25.79 9.78 100.00
38 INT152225 Regulation of Positive_regulation of Tlr4 8 0.53 2.5 1.12 100.00
39 INT316763 Positive_regulation of Positive_regulation of Hspa9 1 0.40 1.7 0.17 100.00
40 INT174339 Positive_regulation of Localization of Mif 7 0.61 8.27 4.95 99.98
41 INT95787 Positive_regulation of Mapk1 568 0.70 226.51 220.94 99.98
42 INT1765 Positive_regulation of Gene_expression of PTGER2 140 0.51 68.68 27 99.98
43 INT69993 Positive_regulation of Gene_expression of Cpox 93 0.55 69.4 22.05 99.98
44 INT101517 Negative_regulation of PPARA 168 0.57 112.24 21.41 99.98
45 INT150676 Positive_regulation of Gene_expression of Mapk1 30 0.45 10.06 12.37 99.98
46 INT96913 Positive_regulation of Mapk8 179 0.69 130.44 32.2 99.98
47 INT131717 Positive_regulation of Gene_expression of Mapk8 18 0.55 14.25 5.02 99.98
48 INT291221 Regulation of Gene_expression of Map3k8 1 0.44 5.59 1 99.98
49 INT92823 Positive_regulation of Gene_expression of MMP1 65 0.68 25.69 14.31 99.98
50 INT129962 Positive_regulation of Gene_expression of MMP13 41 0.65 20.74 8.54 99.98
51 INT95631 Positive_regulation of Gene_expression of MMP8 16 0.50 13.75 5.12 99.98
52 INT110021 Positive_regulation of Gene_expression of Mapk14 29 0.46 19.06 3.86 99.98
53 INT106973 Positive_regulation of Gene_expression of CHAT 3 0.44 0.8 0.5 99.98
54 INT76098 Positive_regulation of Positive_regulation of IRF6 16 0.27 6.05 3.35 99.96
55 INT75136 Binding of Akt1 27 0.27 8.81 4.15 99.96
56 INT104481 Regulation of Mapk8 21 0.50 13.87 8.41 99.96
57 INT3306 Localization of Tbce 16 0.12 8.24 5.71 99.96
58 INT78581 Positive_regulation of Binding of Nfkb1 13 0.66 7.37 2.79 99.96
59 INT4893 Gene_expression of Tacr1 366 0.78 129.67 213.92 99.92
60 INT8413 Gene_expression of Ptgs1 248 0.78 110.17 108.58 99.92
61 INT54571 Positive_regulation of NFKB1 263 0.70 138.99 87.32 99.92
62 INT96622 Localization of Trpv1 110 0.81 59.82 63.25 99.92
63 INT16573 Regulation of Cl 18 0.07 8.69 6.03 99.92
64 INT54573 Positive_regulation of NFYB 6 0.33 2.02 0.87 99.92
65 INT71789 Positive_regulation of MAPK1 396 0.70 234.44 89.27 99.90
66 INT227519 Positive_regulation of Hspa9 22 0.55 16.38 3.83 99.90
67 INT19511 Localization of Il6 212 0.81 118.17 67.67 99.90
68 INT205685 Regulation of Positive_regulation of Casp1 3 0.11 1.62 0.78 99.90
69 INT51921 Gene_expression of Cpox 501 0.73 229.81 157.81 99.88
70 INT28738 Positive_regulation of PLB1 7 0.40 3.36 2.35 99.88
71 INT73252 Positive_regulation of Mthfd1 124 0.59 59.48 18.35 99.88
72 INT178711 Protein_catabolism of Tlr4 15 0.84 6.75 3.19 99.88
73 INT116737 Localization of Mif 63 0.81 52.97 28.11 99.84
74 INT67039 Positive_regulation of Cpox 144 0.65 98.4 33.77 99.84
75 INT162366 Positive_regulation of Map3k8 24 0.50 15.69 3.71 99.84
76 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 99.84
77 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 99.84
78 INT127037 Gene_expression of Ppig 26 0.65 16.08 6.84 99.84
79 INT65054 Positive_regulation of Nfkb1 285 0.70 149.33 126.73 99.84
80 INT27096 Positive_regulation of Nfkb1 325 0.70 195.11 109.06 99.84
81 INT17331 Positive_regulation of JUN 132 0.69 60.4 27.03 99.84
82 INT307141 Regulation of Gene_expression of Ppig 3 0.08 1.84 0.43 99.84
83 INT148846 Positive_regulation of MAP3K3 3 0.26 1.67 2.59 99.84
84 INT219595 Positive_regulation of Gene_expression of Pde4a 3 0.39 2.81 1.11 99.84
85 INT196325 Positive_regulation of Gene_expression of Chd7 7 0.14 4.28 0.76 99.84
86 INT221132 Positive_regulation of Localization of Cxcl2 4 0.44 3.39 0.64 99.84
87 INT1760 Gene_expression of PTGER2 524 0.57 226.94 96.4 99.82
88 INT16428 Positive_regulation of Gtf3a 135 0.20 106.44 26.67 99.82
89 INT190875 Positive_regulation of Fbxo2 1 0.04 2.4 0.75 99.82
90 INT12681 Regulation of Trib3 76 0.53 23.92 26.58 99.82
91 INT48953 Positive_regulation of Nos2 486 0.70 239.85 131.87 99.80
92 INT162365 Gene_expression of Map3k8 33 0.58 22.75 4.95 99.78
93 INT294133 Regulation of Gene_expression of NT5E 4 0.12 1.36 0.71 99.76
94 INT62784 Gene_expression of NT5E 46 0.65 15.95 3.72 99.76
95 INT49439 Gene_expression of Cpox 508 0.73 326.97 130.17 99.74
96 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59 99.74
97 INT48232 Gene_expression of MMP1 245 0.78 96.31 57.72 99.74
98 INT129956 Gene_expression of MMP13 145 0.72 60.48 26.98 99.74
99 INT74587 Gene_expression of MMP8 31 0.78 24.4 14.91 99.74
100 INT242221 Localization of PNPLA4 1 0.03 0.86 0.18 99.74
101 INT12339 Localization of IL8 437 0.81 251.87 117.39 99.72
102 INT120011 Localization of MIF 6 0.58 5.72 2.6 99.72
103 INT89662 Positive_regulation of Gene_expression of App 169 0.70 133.36 25.62 99.70
104 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 99.68
105 INT55944 Positive_regulation of Cpox 214 0.57 105.14 81.4 99.68
106 INT50672 Positive_regulation of CPOX 205 0.44 125.93 60.06 99.68
107 INT66917 Negative_regulation of HSF1 2 0.43 1.33 0.4 99.68
108 INT41728 Gene_expression of CHAT 65 0.75 42.19 12.73 99.68
109 INT21685 Gene_expression of ras 115 0.66 85.6 7.76 99.68
110 INT21686 Positive_regulation of Gene_expression of ras 19 0.42 13.79 4.28 99.68
111 INT61541 Positive_regulation of Gene_expression of Ngfr 7 0.53 2.87 2.75 99.68
112 INT2542 Localization of Calca 2008 0.81 518.3 1408.65 99.64
113 INT5202 Positive_regulation of Gene_expression of Fos 1163 0.70 319.28 684 99.64
114 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 99.64
115 INT73048 Gene_expression of MMP9 268 0.77 159.75 57.81 99.62
116 INT69035 Positive_regulation of Casp1 43 0.69 25.18 10.67 99.62
117 INT16260 Gene_expression of Bdnf 671 0.78 283.44 339.1 99.56
118 INT48593 Positive_regulation of NOS1 420 0.68 226.15 114.71 99.56
119 INT86717 Negative_regulation of Positive_regulation of NOS1 18 0.30 8.88 5.2 99.56
120 INT66758 Binding of Nfkb1 97 0.48 50.65 23.65 99.56
121 INT86361 Positive_regulation of Positive_regulation of NOS1 39 0.53 18.93 10.42 99.56
122 INT66757 Negative_regulation of Binding of Nfkb1 17 0.57 8.14 4.94 99.56
123 INT89026 Positive_regulation of Nt5e 12 0.49 7.25 2.67 99.54
124 INT97078 Positive_regulation of Entpd1 16 0.64 8.54 4.49 99.54
125 INT132103 Positive_regulation of Gene_expression of MAPK8 26 0.46 16.54 3.94 99.54
126 INT177936 Positive_regulation of Negative_regulation of MAPK8 3 0.50 2.1 0.63 99.54
127 INT53949 Positive_regulation of Gene_expression of Cpox 82 0.65 38.12 25.93 99.52
128 INT209013 Regulation of Stub1 1 0.06 0.29 0.46 99.52
129 INT65500 Gene_expression of App 605 0.78 429.94 98.31 99.50
130 INT8357 Gene_expression of KNG1 153 0.75 77.26 68.66 99.50
131 INT77434 Positive_regulation of Gene_expression of Nos2 151 0.69 96.76 38.94 99.48
132 INT123890 Localization of Cxcl2 11 0.67 8.03 3.65 99.48
133 INT109109 Localization of Cxcr1 1 0.16 0.85 0.79 99.48
134 INT105777 Gene_expression of Pde4a 30 0.76 12.67 8.52 99.40
135 INT266485 Protein_catabolism of Dcps 1 0.08 1.08 0.2 99.40
136 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 99.36
137 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 99.36
138 INT99070 Gene_expression of Mapk14 147 0.78 103.99 79.59 99.36
139 INT49141 Gene_expression of Selp 157 0.78 85.22 24.78 99.36
140 INT39153 Positive_regulation of PTGS2 182 0.70 96.16 60.6 99.36
141 INT55908 Gene_expression of Ngfr 74 0.78 34.46 28.8 99.36
142 INT16919 Gene_expression of IL36RN 48 0.48 32.78 13.83 99.36
143 INT237051 Gene_expression of Cxcl11 24 0.64 25.74 5.77 99.36
144 INT174653 Localization of MEFV 15 0.70 12.06 1.93 99.36
145 INT271571 Positive_regulation of MIOX 4 0.09 3.65 0.41 99.36
146 INT59466 Gene_expression of ISYNA1 204 0.77 112.57 35.48 99.32
147 INT76095 Positive_regulation of ISYNA1 117 0.55 79.73 25.86 99.32
148 INT80685 Gene_expression of MAPK8 90 0.72 51.91 13.36 99.26
149 INT87434 Gene_expression of Sell 38 0.77 21.95 8.51 99.26
150 INT156631 Regulation of Positive_regulation of Scn10a 1 0.26 0.61 0.34 99.26
151 INT125079 Negative_regulation of Gene_expression of MAPK8 9 0.39 4.87 1.25 99.26
152 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02 99.24
153 INT6056 Negative_regulation of Gene_expression of Fos 601 0.59 193.05 386.84 99.24
154 INT91417 Positive_regulation of PTGES 36 0.68 18.45 7.64 99.24
155 INT50670 Gene_expression of CPOX 763 0.76 442.13 195.02 99.20
156 INT77677 Positive_regulation of Saa 30 0.49 33.19 11.18 99.20
157 INT325234 Negative_regulation of Il33 1 0.43 0.67 0.37 99.20
158 INT325231 Negative_regulation of Negative_regulation of Il33 1 0.43 0.67 0.34 99.20
159 INT114751 Gene_expression of Mapk1 137 0.76 60.14 39.98 99.18
160 INT96492 Gene_expression of NGFR 24 0.00 12.3 4.59 99.18
161 INT101481 Positive_regulation of Lep 81 0.69 62.59 9.95 99.16
162 INT132997 Localization of Mmp9 59 0.80 45.9 17.61 99.16
163 INT186808 Transcription of TLR4 22 0.69 12.77 3.73 99.16
164 INT92654 Transcription of RETNLB 3 0.01 3.33 1.12 99.16
165 INT5454 Localization of CRH 124 0.79 79.18 41.53 99.14
166 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 99.12
167 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62 99.12
168 INT73502 Positive_regulation of IL10 154 0.69 124.87 43.5 99.12
169 INT62827 Positive_regulation of ICAM1 184 0.70 180.95 36.28 99.12
170 INT19929 Negative_regulation of Positive_regulation of TNF 52 0.59 38.16 16.51 99.12
171 INT97701 Phosphorylation of Mapk14 191 0.82 115.33 100.46 99.08
172 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85 99.08
173 INT187618 Localization of Ppara 13 0.70 6.91 3.09 99.08
174 INT66280 Gene_expression of Nos2 534 0.78 330.78 157.07 99.04
175 INT91932 Positive_regulation of Scn10a 18 0.67 10.39 10.9 99.04
176 INT63340 Positive_regulation of Gene_expression of ICAM1 109 0.70 90.82 20.61 99.04
177 INT49171 Gene_expression of Nos1 241 0.78 140.7 104.76 99.04
178 INT207103 Positive_regulation of Positive_regulation of Pawr 2 0.36 1.45 0.85 99.02
179 INT181488 Positive_regulation of Spg21 13 0.12 15.52 10.03 98.98
180 INT213786 Positive_regulation of Positive_regulation of F2rl3 1 0.27 0.92 0.46 98.98
181 INT3950 Gene_expression of Ptger2 293 0.77 122.28 62.42 98.96
182 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 98.96
183 INT35029 Positive_regulation of Gene_expression of Ptger2 66 0.43 26.37 13.99 98.96
184 INT70776 Positive_regulation of P2rx1 62 0.62 32.55 30.75 98.96
185 INT163995 Negative_regulation of Gene_expression of Ppig 4 0.24 2.07 0.89 98.92
186 INT52188 Positive_regulation of Des 2 0.16 1.56 1.63 98.88
187 INT116950 Negative_regulation of MAPK8 103 0.57 44.48 17.53 98.86
188 INT67981 Positive_regulation of CCL2 165 0.70 136.84 61.85 98.84
189 INT89854 Regulation of Nos2 49 0.61 42.58 24.1 98.84
190 INT77433 Regulation of Gene_expression of Nos2 49 0.62 35.07 16.33 98.84
191 INT55689 Positive_regulation of Transcription of TIMP1 3 0.46 1.02 0.67 98.84
192 INT207091 Positive_regulation of Pawr 2 0.36 1.95 1.1 98.82
193 INT81049 Positive_regulation of CASP1 44 0.67 19.97 5.69 98.80
194 INT158311 Positive_regulation of F2rl3 7 0.51 1.77 1.44 98.78
195 INT65713 Localization of ICAM1 42 0.81 39.55 11.49 98.76
196 INT140338 Negative_regulation of Gene_expression of Il17a 34 0.46 23.82 9.87 98.76
197 INT244376 Regulation of Positive_regulation of Cl 1 0.02 0.86 0.64 98.74
198 INT48408 Gene_expression of ICAM1 494 0.78 340.08 88.6 98.68
199 INT62826 Negative_regulation of Gene_expression of ICAM1 75 0.58 46.39 17.72 98.68
200 INT62525 Positive_regulation of SELE 38 0.70 46 5.25 98.68
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