P:Infliximab

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pChart

Pain Term
Category Drug
Synonyms None
Pain Specific No
Documents 942
Hot Single Events 200
Hot Interactions 57

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Infliximab. They are ordered first by their pain relevance and then by number of times they were reported for Infliximab. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT232417 Binding of Mtx1 and Ifx 1 0.04 0.99 0.86 100.00
2 INT279361 Binding of TNF and KLF1 4 0.00 3.72 2.19 100.00
3 INT239474 Binding of ACR and Ifx 1 0.02 0.36 0.45 100.00
4 INT238641 Binding of TNF and Ifx 1 0.07 0.86 0.84 100.00
5 INT238642 Binding of TNF and Ada 1 0.03 0.86 0.84 100.00
6 INT238639 Cd86 Negative_regulation of Negative_regulation of Bcl2 1 0.01 0.97 0.46 100.00
7 INT182019 Il6 Negative_regulation of Gene_expression of Tnfrsf11b 1 0.22 0.22 0.28 100.00
8 INT194620 Il1 Regulation of Gene_expression of TNF 1 0.04 0 0.16 100.00
9 INT279369 Binding of ADA and Ifx 1 0.29 0.27 0.35 100.00
10 INT311963 Ifx Negative_regulation of FBN1 1 0.00 0.44 0.5 100.00
11 INT182022 TNF Positive_regulation of Gene_expression of Tnfrsf11b 1 0.06 1.56 0.98 99.78
12 INT126555 Binding of Ighg1 and Tnf 1 0.35 2.2 0.8 99.76
13 INT173977 Binding of TNF and Ighg1 1 0.03 0.28 0.39 99.74
14 INT152747 Negative_regulation of Abmm Positive_regulation of Tnf 1 0.01 0.64 0.2 99.38
15 INT182021 Binding of TNF and Il6 2 0.04 0.74 0.53 99.36
16 INT231758 IRF6 Regulation of Gene_expression of HMOX1 1 0.08 0.23 0.05 99.30
17 INT353741 Binding of IGHE and Aia1 1 0.00 1.16 1.06 99.24
18 INT152746 Abmm Positive_regulation of Tnf 1 0.01 0.64 0.2 99.08
19 INT268236 Binding of TNF and fc 1 0.04 0.2 0.29 98.56
20 INT284481 Binding of ABCA1 and Ighg1 1 0.00 1.39 0.7 97.86
21 INT182024 TNF Positive_regulation of Gene_expression of Il6 1 0.05 1.58 0.94 97.80
22 INT238638 Gopc Negative_regulation of Gene_expression of Bax 1 0.04 0.85 0.45 97.64
23 INT203101 Binding of Aes and Mtx1 2 0.25 0.24 0.88 97.40
24 INT320121 Binding of PTEN and TNF 1 0.05 0.76 0.49 96.40
25 INT131156 Binding of RUNX1 and TNF 2 0.03 3.44 1.42 95.36
26 INT353010 Binding of GJA8 and TNF 1 0.02 0.24 0.33 94.76
27 INT182020 Tnfrsf11b Regulation of Il6 1 0.27 0.16 0.22 94.56
28 INT353009 Binding of GJA8 and VSIG1 1 0.00 0 0.29 93.96
29 INT271875 IL1RN Negative_regulation of Binding of IL1B 1 0.01 1.3 1.01 93.40
30 INT306259 HDAC9 Negative_regulation of Gene_expression of TNF 1 0.21 0.89 0.78 93.32
31 INT306258 HDAC4 Negative_regulation of Gene_expression of TNF 1 0.09 0.89 0.78 93.32
32 INT122163 Binding of TNF and TNFRSF1B 6 0.44 6.06 2.41 92.96
33 INT172082 TNF Regulation of SFTPA1 1 0.05 0.85 0.5 90.96
34 INT134427 Alb Regulation of GGT1 1 0.05 0.7 0.35 90.92
35 INT182023 Binding of TNF and Positive_regulation of Gene_expression of Il6 1 0.05 0.07 0.11 90.40
36 INT239037 Binding of Cd28 and Cd86 9 0.16 3.69 2.14 90.08
37 INT239038 Negative_regulation of Binding of Cd28 and Cd86 3 0.17 1.5 1.05 90.08
38 INT252033 Binding of HLA-DQA2 and KLRD1 1 0.00 0.54 0.29 89.76
39 INT204090 Binding of KIR2DL2 and KIR2DS1 1 0.03 0.41 0.29 89.08
40 INT204089 Binding of KIR2DL3 and KIR2DS1 1 0.03 0.41 0.29 89.08
41 INT293704 Binding of TNF and DDX41 1 0.00 1.01 0.61 88.60
42 INT353730 Binding of FCGR2A and FCGR3A 1 0.33 0.5 0.41 88.36
43 INT277832 Binding of TNFRSF1B and NPEPPS 1 0.01 1.1 0.88 88.24
44 INT224687 Il1 Positive_regulation of Bmp2 1 0.00 0.3 0.31 87.80
45 INT181862 Binding of MPO and PRTN3 2 0.16 1.18 0.38 87.28
46 INT148704 Binding of TNF and TNFRSF1A 5 0.44 3.3 2.09 87.28
47 INT277831 Binding of TNFRSF1A and NPEPPS 1 0.01 1.1 0.87 87.28
48 INT231771 Binding of HMOX1 and TNF 2 0.14 1.41 0.04 87.20
49 INT331799 IL8 Negative_regulation of Mapk14 1 0.01 1.6 0.42 86.68
50 INT279359 Binding of ADA and TNF 1 0.20 2.61 1.91 85.92
51 INT231797 Glrb Regulation of Negative_regulation of TNF 1 0.02 1.49 0.25 84.72
52 INT353011 GJA8 Regulation of USE1 1 0.00 0.35 0.13 83.84
53 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17 82.72
54 INT147755 Binding of GNRH1 and TNF 1 0.32 2.37 0.79 82.68
55 INT299783 Binding of Cd28 and Cd80 7 0.14 6.49 2.49 82.36
56 INT333969 Binding of TNF and Cd4 1 0.03 1.28 0.39 81.60
57 INT326303 Binding of CRP and FKBP4 1 0.15 1.22 0.41 80.72
58 INT329297 Binding of Cd226 and Aff3 1 0.18 1.54 0.64 79.72
59 INT176473 IL10 Positive_regulation of Gene_expression of PECAM1 1 0.05 1.1 0.75 79.28
60 INT188692 Binding of Cd40 and Cd40lg 32 0.34 22.95 6.62 79.16
61 INT172081 TNF Regulation of IFNA1 1 0.03 1.13 0.5 79.08
62 INT320120 MTX1 Positive_regulation of PTEN 1 0.04 0.09 0.82 75.84
63 INT275552 Tlr4 Positive_regulation of Gene_expression of Il1 1 0.00 1.28 0.59 74.32
64 INT152748 Negative_regulation of Cpox Negative_regulation of Localization of Tnf 1 0.17 0.98 0.21 74.16
65 INT103796 IL1B Positive_regulation of Gene_expression of SELE 2 0.08 1 0.98 74.00
66 INT176476 TNF Positive_regulation of Gene_expression of SELE 1 0.04 0.57 0.63 74.00
67 INT285569 TNF Negative_regulation of Gene_expression of Il6 1 0.03 2.83 1.46 73.28
68 INT173112 IL1B Positive_regulation of Gene_expression of VCAM1 2 0.43 1.34 0.76 72.64
69 INT149192 TNF Positive_regulation of Gene_expression of VCAM1 3 0.57 1.4 0.76 72.64
70 INT133050 TNF Positive_regulation of Gene_expression of ICAM1 3 0.67 1.91 0.94 72.00
71 INT176475 IL1B Positive_regulation of Gene_expression of ICAM1 1 0.02 0.56 0.62 72.00
72 INT231796 Binding of Fcr and Sle1 1 0.01 1.62 0.33 71.24
73 INT172083 TNF Regulation of Regulation of IFNA1 1 0.03 0.91 0.22 70.88
74 INT264504 Binding of CRYGD and PTPN22 1 0.04 0.42 0.31 67.04
75 INT306271 IL1A Positive_regulation of Gene_expression of IL6 1 0.30 0.85 0.8 64.60
76 INT176479 IL17A Positive_regulation of Gene_expression of TIMP1 1 0.02 1.33 0.74 64.28
77 INT254578 Binding of TNF and Tst 1 0.02 1.57 0.13 63.84
78 INT248271 IL6 Regulation of Gene_expression of Crp 3 0.27 1.7 0.73 63.28
79 INT299041 SPARC Regulation of Gene_expression of NPEPPS 1 0.01 0.83 0.42 62.96
80 INT299040 Binding of COL7A1 and SPARC 1 0.02 0.7 0.42 62.96
81 INT186393 Binding of TNF and Tnfrsf1a 9 0.37 8.55 1.29 60.92
82 INT186385 Binding of TNF and Tnfrsf1b 4 0.30 3.24 0.42 60.92
83 INT231760 TNF Positive_regulation of Protein_catabolism of HMOX1 1 0.31 0.41 0.06 60.72
84 INT183921 Binding of Crp and Ttr 1 0.00 1.18 0.03 58.80
85 INT116441 IL1B Positive_regulation of Gene_expression of CCL2 2 0.04 0.62 0.65 58.60
86 INT103651 IL1B Positive_regulation of Gene_expression of IL8 6 0.78 1.23 0.98 58.60
87 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48 58.60
88 INT176470 TNF Positive_regulation of Gene_expression of CCL2 1 0.15 0.62 0.58 58.24
89 INT103133 TNF Positive_regulation of Gene_expression of IL8 2 0.48 1.26 0.96 58.24
90 INT89379 TNF Positive_regulation of Gene_expression of IL6 5 0.50 4.37 1.69 58.24
91 INT176471 TNF Positive_regulation of Gene_expression of IL1B 1 0.02 0.61 0.57 58.24
92 INT254242 TNF Positive_regulation of Gene_expression of DKK1 1 0.14 1.24 0.91 57.92
93 INT171974 Binding of Tnfrsf11a and Tnfsf11 14 0.35 13.11 3.11 57.84
94 INT174657 IL8 Positive_regulation of Gene_expression of LTBR 1 0.01 1.53 0.3 57.44
95 INT174659 TNF Positive_regulation of Gene_expression of LTBR 1 0.22 1.54 0.3 57.44
96 INT174658 TNF Positive_regulation of Gene_expression of ITGAM 1 0.16 1.54 0.3 57.04
97 INT172125 Binding of Tnfrsf11b and Tnfrsf11a 2 0.17 2.12 0.39 54.24
98 INT220117 Il6 Positive_regulation of TNF 1 0.01 2.45 0.63 51.68
99 INT311950 FBN1 Positive_regulation of Gene_expression of PGF 1 0.00 0.15 0.26 51.04
100 INT293703 Binding of DDX41 and C21orf91 1 0.00 0.99 0.42 50.68
101 INT197092 TNF Regulation of VEGFA 4 0.21 2.78 1.22 50.00
102 INT248318 RETN Regulation of VEGFA 1 0.00 0.43 0.26 50.00
103 INT311968 TNF Regulation of Transcription of IFNA1 1 0.01 0.59 0.25 50.00
104 INT277995 TNF Positive_regulation of Gene_expression of Tnfrsf1a 1 0.03 1.48 0.22 50.00
105 INT277996 TNF Positive_regulation of Tnfrsf1a 1 0.03 1.48 0.22 50.00
106 INT353070 ADAM17 Positive_regulation of TNF 1 0.19 1.66 0.08 50.00
107 INT279360 ADA Negative_regulation of Gene_expression of IFNG 1 0.06 0.51 0.44 49.84
108 INT186128 Binding of CD2 and CD58 8 0.10 7.59 2.76 46.48
109 INT194578 Binding of HOXA10 and BTG3 1 0.00 0.66 0.24 44.44
110 INT186125 Negative_regulation of Binding of CD2 and CD58 3 0.12 3.04 1.06 43.92
111 INT252634 Binding of TNF and Tnfrsf1a 4 0.02 2.4 0.46 43.28
112 INT130721 Binding of IL1B and IL1RN 6 0.05 5.29 2.85 42.44
113 INT285467 Negative_regulation of Binding of IL1B and IL1RN 1 0.05 1.33 0.61 42.44
114 INT306264 Binding of IL1A and MTX1 1 0.09 0.74 0.61 42.24
115 INT352163 SNRPA Positive_regulation of Localization of IL10 1 0.06 0.87 0.23 39.72
116 INT252633 Binding of TNF and Tnfrsf1b 4 0.05 3.66 1.54 35.04
117 INT231349 Il10 Negative_regulation of Gene_expression of TNF 2 0.23 1.82 0.67 31.36
118 INT251580 Il13 Negative_regulation of Gene_expression of TNF 1 0.08 0.96 0.27 31.36
119 INT251567 Il4 Negative_regulation of Gene_expression of Il10 1 0.01 0.96 0.27 31.36
120 INT251581 Il4 Negative_regulation of Gene_expression of TNF 1 0.05 0.95 0.26 31.36
121 INT293708 Binding of TNF and Trap1 1 0.00 0.94 0.27 31.28
122 INT253772 Binding of THBD and Hmgb1 1 0.05 0.95 0.12 30.96
123 INT253769 Binding of Hmgb1 and Il1 1 0.01 0.27 0 30.00
124 INT264300 CTSK Positive_regulation of CYP27A1 1 0.03 0.69 0.07 24.76
125 INT183387 Il6 Positive_regulation of Gene_expression of Il10 2 0.19 1.8 0.63 22.88
126 INT171976 Il18 Positive_regulation of Gene_expression of IFNA1 1 0.01 1.37 0.64 18.20
127 INT132318 Ghrl Positive_regulation of Localization of GH1 5 0.32 4.49 0.84 16.24
128 INT352961 Ghrl Positive_regulation of Localization of GHSR 1 0.18 1.19 0.21 16.24
129 INT277705 SMAP2 Regulation of TNF 1 0.01 1.23 0.25 15.20
130 INT71176 Binding of ICAM1 and ITGB2 4 0.21 4.93 1.07 14.12
131 INT194621 TNF Positive_regulation of Gene_expression of Klrk1 1 0.05 0.5 0.32 11.96
132 INT194614 Il15 Positive_regulation of Gene_expression of Klrk1 1 0.04 0.5 0.32 11.68
133 INT254243 Binding of HOMER1 and MRI1 1 0.03 1.99 1.57 10.64
134 INT295472 IRF6 Positive_regulation of Gene_expression of TNF 2 0.16 0.95 0.27 9.44
135 INT224701 Timp3 Negative_regulation of TNF 1 0.01 0.65 0.34 8.88
136 INT211129 Negative_regulation of Binding of P4HB and TNF 1 0.10 0.97 0.9 7.80
137 INT211128 Binding of P4HB and TNF 1 0.09 0.97 0.9 7.28
138 INT306255 IRF6 Positive_regulation of TFAM 1 0.01 0 0.07 5.60
139 INT306260 TLR4 Positive_regulation of TFAM 1 0.01 0 0.07 5.60
140 INT277791 Binding of Icam1 and Itgal 1 0.03 0.37 0.17 5.52
141 INT149117 Binding of CD80 and CTLA4 31 0.52 12.7 7.73 5.00
142 INT155484 Binding of CD86 and CTLA4 15 0.52 8.85 6.09 5.00
143 INT176477 Binding of CXCR3 and CXCL10 14 0.25 10.61 5.87 5.00
144 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65 5.00
145 INT182194 Binding of IL8 and CXCR2 10 0.56 7.14 4.16 5.00
146 INT121651 Binding of CXCL12 and CXCR4 13 0.48 17.61 3.52 5.00
147 INT194647 Binding of CD28 and CD80 15 0.40 4.9 3.22 5.00
148 INT186126 Binding of CD28 and CTLA4 9 0.52 4.13 3.12 5.00
149 INT208572 Binding of IL8 and CXCR1 6 0.33 5.2 3.08 5.00
150 INT182635 Binding of CCR5 and CCL5 2 0.09 4.19 3 5.00
151 INT318996 Binding of CCR3 and CCL5 1 0.07 3.39 2.9 5.00
152 INT319003 Binding of CCR1 and CCL5 1 0.08 3.38 2.89 5.00
153 INT175329 Binding of ICAM1 and ITGAL 14 0.18 10.06 2.81 5.00
154 INT318998 IFNA1 Positive_regulation of Localization of CXCL10 1 0.15 2.09 2.39 5.00
155 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36 5.00
156 INT126717 Binding of Il6 and Il6st 3 0.21 3.35 2.22 5.00
157 INT194646 Binding of CD28 and CD86 7 0.40 2.69 2.21 5.00
158 INT157767 Binding of TLR4 and LY96 8 0.54 4.05 1.95 5.00
159 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87 5.00
160 INT194863 Binding of IL1R1 and IL1RN 5 0.09 2.23 1.64 5.00
161 INT306745 Binding of Il12a and IL23A 1 0.10 3.25 1.56 5.00
162 INT254205 Binding of Myd88 and Tlr4 12 0.19 3.17 1.54 5.00
163 INT126718 Binding of Il6 and Il6r 3 0.09 2.33 1.49 5.00
164 INT218309 Binding of CRP and IL6 3 0.23 4.78 1.36 5.00
165 INT265213 Binding of Ctla4 and Cd86 2 0.13 1.93 1.31 5.00
166 INT254355 PF4 Positive_regulation of IFNA1 1 0.04 1.23 1.26 5.00
167 INT254210 Binding of Cxcr2 and Ccl2 1 0.08 2.39 1.25 5.00
168 INT186355 Il23a Positive_regulation of Gene_expression of Il17a 4 0.12 3 1.24 5.00
169 INT194619 Il15 Positive_regulation of Gene_expression of TNF 1 0.24 2.23 1.2 5.00
170 INT231769 TNF Negative_regulation of Gene_expression of HMOX1 1 0.26 4.75 1.15 5.00
171 INT308172 Rvm Positive_regulation of Phosphorylation of GRIN1 1 0.50 0.68 1.14 5.00
172 INT83616 Binding of IL6 and IL8 5 0.09 5.8 1.11 5.00
173 INT308173 Binding of DRG1 and Tnfrsf1b 1 0.01 1.64 1.1 5.00
174 INT333966 Binding of Il6r and Il6st 1 0.01 1.74 1.1 5.00
175 INT119108 Binding of LTBR and TNF 2 0.15 1.47 1.07 5.00
176 INT176474 Binding of CXCR3 and CXCL9 3 0.22 1.9 1.05 5.00
177 INT266742 GOPC Regulation of Positive_regulation of ACR 1 0.02 0.36 1.05 5.00
178 INT181450 Binding of Ccr5 and Ccl3 4 0.18 2.19 1.03 5.00
179 INT206074 Binding of IL6 and IL6ST 7 0.32 3.79 1.01 5.00
180 INT228498 Il10 Negative_regulation of Hand1 1 0.03 1.4 0.99 5.00
181 INT228496 Il4 Negative_regulation of Hand1 1 0.02 1.4 0.99 5.00
182 INT228495 Il13 Negative_regulation of Hand1 1 0.01 1.4 0.98 5.00
183 INT187111 TIMP2 Regulation of MMP9 1 0.23 1.47 0.97 5.00
184 INT308169 Negative_regulation of Mapk14 Negative_regulation of Ltp 1 0.01 0.79 0.95 5.00
185 INT285561 Il23a Positive_regulation of Gene_expression of Il22 2 0.06 2.45 0.93 5.00
186 INT265210 Binding of Ctla4 and Cd28 2 0.16 1.45 0.93 5.00
187 INT302828 Mapkapk5 Positive_regulation of Mapk1 1 0.07 1.38 0.91 5.00
188 INT221386 Tlr4 Positive_regulation of Gene_expression of IL8 6 0.14 3.53 0.9 5.00
189 INT183269 Binding of CEBPB and CPOX 1 0.07 1.61 0.89 5.00
190 INT249347 Binding of FOS and JUN 4 0.19 6.15 0.89 5.00
191 INT166983 Binding of HLA-B and HSPG2 4 0.08 4.66 0.88 5.00
192 INT187290 Binding of HEY1 and Gtf3a 1 0.00 6.18 0.83 5.00
193 INT188567 IRF6 Positive_regulation of Gene_expression of CD28 1 0.05 1.28 0.82 5.00
194 INT201945 Binding of CXCR1 and CXCR2 3 0.14 0.84 0.8 5.00
195 INT302831 Binding of Creb1 and Mapkapk5 1 0.07 1.3 0.79 5.00
196 INT184116 Il10 Positive_regulation of Stat3 2 0.18 1.15 0.77 5.00
197 INT194644 Tlr4 Positive_regulation of TNF 6 0.58 2.42 0.76 5.00
198 INT308176 TNF Regulation of Tnfrsf1a 1 0.05 1.19 0.75 5.00
199 INT211127 Regulation of Binding of MTX1 and TNF 1 0.22 0.71 0.74 5.00
200 INT211130 Binding of MTX1 and TNF 1 0.18 0.7 0.73 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Infliximab. They are ordered first by their pain relevance and then by number of times they were reported in Infliximab. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 100.00
2 INT6481 Binding of TNF 624 0.48 510.2 214.82 100.00
3 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 100.00
4 INT232413 Positive_regulation of Ifx 9 0.49 2.58 4.13 100.00
5 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99 100.00
6 INT56160 Binding of Ifx 14 0.36 11.39 5.74 100.00
7 INT50212 Gene_expression of Ifx 33 0.75 32.17 7.26 100.00
8 INT3545 Positive_regulation of Mtx1 27 0.42 11.97 14.83 100.00
9 INT232414 Negative_regulation of Ifx 6 0.42 3.28 2.26 100.00
10 INT5609 Regulation of Ifx 6 0.60 5.73 3.5 100.00
11 INT86411 Negative_regulation of Negative_regulation of TNF 24 0.42 17.6 7.89 100.00
12 INT194609 Regulation of Gene_expression of Il15 1 0.18 3.33 1.86 100.00
13 INT211176 Binding of AGTRAP 1 0.01 0.38 0.47 100.00
14 INT353015 Negative_regulation of Positive_regulation of AGTRAP 1 0.01 0.35 0.49 100.00
15 INT353018 Positive_regulation of AGTRAP 1 0.01 0.34 0.49 100.00
16 INT25906 Negative_regulation of Cish 6 0.29 5.41 3.17 100.00
17 INT11353 Gene_expression of SLC3A2 13 0.58 7.31 2.33 100.00
18 INT8707 Localization of LILRB1 2 0.60 1.5 1.5 100.00
19 INT238636 Regulation of Ada 2 0.15 1.12 1.06 100.00
20 INT254248 Regulation of Rf 2 0.16 0.46 0.53 100.00
21 INT1710 Gene_expression of Etn1 13 0.37 3.85 1.39 100.00
22 INT279366 Positive_regulation of Localization of ADA 2 0.42 4.37 0.76 100.00
23 INT170444 Binding of Gopc 172 0.39 45.05 20.71 100.00
24 INT239471 Positive_regulation of Positive_regulation of Ifx 1 0.22 0.15 0.47 100.00
25 INT181867 Positive_regulation of Positive_regulation of Neu1 1 0.49 0.93 0.72 100.00
26 INT181876 Positive_regulation of Positive_regulation of BTG3 1 0.25 0.93 0.72 100.00
27 INT239017 Regulation of Positive_regulation of Sell 1 0.22 0.63 0.49 100.00
28 INT23937 Gene_expression of EDNRA 103 0.65 55.63 24.67 100.00
29 INT11802 Gene_expression of KLF1 11 0.65 6.81 1.41 100.00
30 INT5969 Gene_expression of Il1a 221 0.75 96.31 71.38 100.00
31 INT72532 Regulation of Gene_expression of Il1a 13 0.54 4.91 6.71 100.00
32 INT61452 Gene_expression of IL1RAP 15 0.58 7.21 5.09 100.00
33 INT67796 Negative_regulation of CTLA4 13 0.39 8.36 2.39 100.00
34 INT125530 Negative_regulation of Gene_expression of IL1RAP 1 0.12 1.13 0.57 100.00
35 INT125531 Negative_regulation of IL1RAP 1 0.12 1.13 0.57 100.00
36 INT133568 Regulation of TNFRSF1B 1 0.01 0.54 0.37 100.00
37 INT163134 Gene_expression of ACR 78 0.65 30.39 38.48 99.98
38 INT2064 Positive_regulation of BTG3 29 0.49 25.58 15.37 99.98
39 INT182012 Negative_regulation of Gene_expression of Tnfrsf11b 1 0.29 0.91 0.63 99.98
40 INT87433 Positive_regulation of Sell 10 0.49 5.04 3.14 99.98
41 INT63341 Negative_regulation of ICAM1 42 0.59 30.45 9.5 99.98
42 INT6489 Positive_regulation of Gene_expression of Tnf 140 0.70 92.31 67.85 99.98
43 INT47692 Negative_regulation of Positive_regulation of Bdnf 18 0.59 9.64 13.14 99.98
44 INT62526 Negative_regulation of SELE 17 0.51 15.24 4.19 99.98
45 INT93531 Negative_regulation of Gene_expression of Tnfsf11 15 0.43 7.74 2.84 99.98
46 INT22285 Negative_regulation of Mtx1 16 0.49 7.84 8.98 99.96
47 INT188344 Positive_regulation of Gene_expression of Foxp3 10 0.36 5.97 2.56 99.96
48 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 99.92
49 INT133549 Gene_expression of Il15 42 0.69 27.84 14.74 99.92
50 INT67597 Negative_regulation of Das 17 0.37 9.95 5.05 99.92
51 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71 99.92
52 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 99.92
53 INT177468 Negative_regulation of Gene_expression of MTRF1 1 0.03 0.83 0.58 99.92
54 INT52800 Negative_regulation of Gene_expression of Tnf 142 0.59 92.27 55.47 99.92
55 INT238637 Binding of Ada 2 0.26 1.01 0.94 99.90
56 INT19392 Gene_expression of Ada 9 0.77 7.4 3.17 99.90
57 INT196393 Negative_regulation of Cd86 9 0.22 4.24 1.17 99.90
58 INT110023 Negative_regulation of Mapk14 127 0.59 84.27 45.42 99.88
59 INT78524 Positive_regulation of Neu1 6 0.67 8.9 4.4 99.84
60 INT181267 Gene_expression of USE1 12 0.32 7.6 2.7 99.84
61 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 99.84
62 INT183207 Negative_regulation of USE1 14 0.18 10.97 4 99.84
63 INT58288 Positive_regulation of Gene_expression of Crp 83 0.61 82.23 23.7 99.84
64 INT137153 Positive_regulation of VIS1 2 0.04 1.52 0.31 99.84
65 INT4067 Negative_regulation of Esr1 97 0.50 43.45 17.52 99.82
66 INT43727 Negative_regulation of Gene_expression of MMP3 16 0.40 4.81 7.18 99.82
67 INT21579 Negative_regulation of Gene_expression of TIMP1 25 0.57 12.41 6.94 99.82
68 INT117598 Regulation of ACR 118 0.26 41.25 48.01 99.80
69 INT86705 Gene_expression of BTG3 41 0.65 37.29 8.29 99.80
70 INT182320 Binding of MTX1 14 0.18 8.5 7.65 99.80
71 INT123459 Gene_expression of Tnfrsf11b 35 0.58 24.16 7.26 99.78
72 INT131359 Positive_regulation of Gene_expression of Cd4 40 0.58 22.43 7.53 99.78
73 INT87824 Positive_regulation of Gene_expression of Sell 8 0.52 3.37 2.62 99.78
74 INT55670 Negative_regulation of Gene_expression of Tnf 83 0.59 57.16 46.33 99.78
75 INT145594 Gene_expression of Mtx1 64 0.57 35.33 30.35 99.76
76 INT8836 Positive_regulation of SFTPA1 36 0.47 28.37 23.59 99.76
77 INT11346 Binding of Mtx1 39 0.41 24.88 21.21 99.76
78 INT155944 Gene_expression of Foxp3 66 0.66 24.37 9.12 99.76
79 INT9220 Gene_expression of Ighg1 125 0.77 85.74 15.92 99.76
80 INT35406 Localization of Tnf 94 0.81 64.63 31.65 99.76
81 INT44920 Negative_regulation of IK 18 0.41 9.9 7.16 99.76
82 INT100497 Gene_expression of Aia1 9 0.25 11.78 7.51 99.76
83 INT53573 Negative_regulation of Localization of Tnf 19 0.59 11.57 8.54 99.76
84 INT9660 Regulation of TNF 363 0.62 312.94 139.99 99.74
85 INT16259 Positive_regulation of Bdnf 336 0.70 183.48 209.82 99.74
86 INT93534 Gene_expression of Tnfsf11 185 0.77 119.26 33.66 99.74
87 INT132161 Gene_expression of MTX1 48 0.58 26.55 32.32 99.72
88 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87 99.72
89 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 99.72
90 INT133553 Negative_regulation of Gene_expression of Il15 5 0.52 2.01 1.16 99.72
91 INT194610 Positive_regulation of Gene_expression of Il15 5 0.33 3.45 2.19 99.72
92 INT119962 Negative_regulation of Negative_regulation of Crp 2 0.45 3.24 0.81 99.72
93 INT6513 Positive_regulation of Gene_expression of BGLAP 24 0.67 11.69 3.96 99.72
94 INT6516 Positive_regulation of BGLAP 45 0.67 26.61 9.9 99.72
95 INT181316 Positive_regulation of ALPL 5 0.65 1.65 1.6 99.72
96 INT11238 Positive_regulation of ADA 33 0.70 39.7 9.98 99.70
97 INT106264 Negative_regulation of Gene_expression of Vcam1 13 0.53 10.47 3.55 99.70
98 INT56450 Negative_regulation of Gene_expression of Icam1 33 0.52 27.21 10.15 99.70
99 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 99.68
100 INT80222 Negative_regulation of Bcl2 82 0.58 69.16 13.18 99.68
101 INT10214 Gene_expression of VIM 153 0.78 115.88 16.29 99.68
102 INT283663 Positive_regulation of Gene_expression of TSS 1 0.04 0 0.26 99.68
103 INT53262 Gene_expression of TSS 6 0.52 1.35 0.37 99.68
104 INT181875 Regulation of Binding of BTG3 1 0.12 0.06 0.17 99.68
105 INT211714 Regulation of Gene_expression of VIM 4 0.43 3.77 0.52 99.68
106 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 99.66
107 INT177467 Negative_regulation of MTRF1 22 0.05 11.84 5.57 99.66
108 INT147514 Negative_regulation of CRYGD 15 0.13 9.41 5.1 99.66
109 INT9239 Regulation of Gene_expression of IL6 106 0.61 75.24 36.53 99.66
110 INT191533 Gene_expression of TRAF3IP2 2 0.36 1.83 0.62 99.64
111 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 99.64
112 INT6852 Localization of TNF 883 0.81 705.95 270.84 99.60
113 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18 99.60
114 INT134590 Localization of ADA 7 0.65 8.43 3.96 99.60
115 INT16478 Positive_regulation of Plg 29 0.45 18.07 4.07 99.60
116 INT24873 Binding of KLF1 12 0.07 6.73 3.1 99.60
117 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 99.58
118 INT115370 Gene_expression of PSIP1 22 0.65 9.45 5.68 99.58
119 INT139939 Positive_regulation of Arhgef2 1 0.27 0.1 0.15 99.58
120 INT68202 Gene_expression of ADA 26 0.68 23.15 5.18 99.56
121 INT203099 Negative_regulation of Aes 3 0.25 0.82 1.25 99.56
122 INT10166 Localization of Tnf 237 0.81 153.95 88.64 99.56
123 INT26069 Positive_regulation of Positive_regulation of IFNA1 26 0.50 16.61 4.76 99.56
124 INT192073 Positive_regulation of Gene_expression of ADA 8 0.47 10.35 1.12 99.56
125 INT5307 Regulation of Tnf 87 0.62 78.71 43.4 99.54
126 INT19428 Gene_expression of MTRF1 42 0.08 27.17 10.43 99.52
127 INT112967 Regulation of Mcpt1 15 0.54 13.03 8.58 99.52
128 INT10835 Regulation of IL8 79 0.49 53.04 24.14 99.52
129 INT183979 Localization of PSIP1 2 0.73 1.37 0.59 99.50
130 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 99.48
131 INT15514 Negative_regulation of Crp 275 0.59 194.6 64.86 99.48
132 INT52732 Negative_regulation of CRP 169 0.59 138.47 40.33 99.48
133 INT65489 Regulation of Gene_expression of Crp 28 0.59 29.17 7.56 99.48
134 INT49214 Gene_expression of Cd4 269 0.78 154.22 34.05 99.48
135 INT115213 Regulation of SFTPA1 13 0.32 6.91 7.11 99.48
136 INT44015 Binding of Cd86 16 0.31 5.92 3.58 99.48
137 INT148341 Gene_expression of MAS1 9 0.65 4.19 0.68 99.48
138 INT160830 Gene_expression of Siglece 6 0.39 2.37 0.85 99.48
139 INT48406 Gene_expression of Icam1 277 0.78 238.28 81.71 99.44
140 INT49105 Gene_expression of Vcam1 157 0.78 157.27 43.01 99.44
141 INT49487 Gene_expression of Sele 65 0.76 68.11 19.41 99.44
142 INT91337 Gene_expression of CCL4 29 0.75 16.23 8.64 99.44
143 INT2006 Gene_expression of fc 104 0.34 64.91 19.08 99.44
144 INT56042 Binding of IGBP1 2 0.01 2.1 0.47 99.42
145 INT191311 Binding of Das 3 0.03 2.56 0.99 99.40
146 INT11649 Negative_regulation of Positive_regulation of Gpt 25 0.59 13.94 10.87 99.38
147 INT60434 Negative_regulation of Positive_regulation of Tnf 20 0.46 10.01 10.64 99.38
148 INT78024 Gene_expression of ACLY 73 0.75 59.15 18.54 99.36
149 INT29496 Gene_expression of MMP3 136 0.75 49.49 41.78 99.36
150 INT1759 Gene_expression of TIMP1 267 0.77 133.87 59.29 99.36
151 INT139940 Regulation of Arhgef2 1 0.25 0.1 0.15 99.36
152 INT19472 Gene_expression of Il1 554 0.76 419.75 175.35 99.34
153 INT2065 Binding of BTG3 15 0.36 10.9 4.65 99.34
154 INT76149 Gene_expression of Das 18 0.37 6.55 3.92 99.34
155 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58 99.34
156 INT17326 Binding of Plg 14 0.43 11.72 1.94 99.34
157 INT127283 Regulation of Gene_expression of HMOX1 14 0.61 11.8 1.28 99.30
158 INT22454 Regulation of Crp 213 0.62 160.67 49.24 99.28
159 INT22481 Gene_expression of CADM1 28 0.65 30.26 8.5 99.28
160 INT22482 Negative_regulation of Gene_expression of CADM1 6 0.49 3.2 1.8 99.28
161 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 99.26
162 INT11047 Positive_regulation of Positive_regulation of IL6 45 0.66 28.7 9.37 99.26
163 INT177471 Localization of MTRF1 5 0.06 3.46 1.4 99.24
164 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1 99.24
165 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 99.20
166 INT68299 Binding of Tnf 17 0.39 12.55 7.49 99.20
167 INT113671 Negative_regulation of Mmp3 26 0.49 6.33 7.88 99.20
168 INT76008 Positive_regulation of ADAR 7 0.60 2.24 2 99.16
169 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 99.12
170 INT130176 Positive_regulation of Gene_expression of CRP 125 0.66 137.06 25.9 99.12
171 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 99.12
172 INT79545 Positive_regulation of Gene_expression of ESR1 82 0.64 39.42 12.18 99.12
173 INT25610 Positive_regulation of Gene_expression of Il1 136 0.67 104.43 43.86 99.12
174 INT195060 Gene_expression of ALPL 9 0.73 4.82 1.3 99.10
175 INT6515 Gene_expression of BGLAP 110 0.75 45.13 10.81 99.10
176 INT34057 Negative_regulation of Gene_expression of IFNA1 65 0.58 43.46 17.25 99.08
177 INT5058 Positive_regulation of IFNA1 356 0.70 245.75 60.52 99.06
178 INT49930 Binding of Ighg1 21 0.37 13.27 2.43 99.06
179 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 99.04
180 INT8799 Negative_regulation of Csrp1 24 0.58 11.01 6.86 99.02
181 INT263019 Gene_expression of DEFA6 4 0.25 4.14 1.17 99.02
182 INT6478 Negative_regulation of Binding of TNF 36 0.58 30.42 13.31 98.96
183 INT116528 Gene_expression of HMOX1 106 0.78 86.13 12.8 98.96
184 INT143230 Gene_expression of CRYGD 61 0.65 52.11 15.93 98.96
185 INT17237 Regulation of Esr1 74 0.43 49.09 17.25 98.96
186 INT89240 Gene_expression of VEGFC 23 0.75 15.94 2.03 98.96
187 INT89239 Negative_regulation of Gene_expression of VEGFC 2 0.39 1.11 0.59 98.96
188 INT9210 Regulation of IL6 166 0.62 125.61 49.95 98.94
189 INT8640 Positive_regulation of HSD11B1 332 0.67 377.84 22.36 98.90
190 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 98.88
191 INT12087 Regulation of Localization of TNF 44 0.62 28.71 15.17 98.88
192 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 98.84
193 INT17564 Gene_expression of Gpt 322 0.75 208.51 60.36 98.84
194 INT6486 Positive_regulation of Tnf 168 0.70 123.47 66.05 98.82
195 INT158070 Localization of Aes 23 0.65 19.93 10.9 98.80
196 INT62830 Gene_expression of VCAM1 149 0.78 125.23 32.4 98.78
197 INT87434 Gene_expression of Sell 38 0.77 21.95 8.51 98.78
198 INT353727 Gene_expression of DACT3 1 0.14 7.37 1.06 98.76
199 INT14700 Regulation of IFNA1 111 0.45 66.16 21.52 98.76
200 INT353724 Gene_expression of MTSS1 1 0.21 3.56 0.48 98.76
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