P:Inward rectifier potassium channel

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pChart

Pain Term
Category family
Synonyms None
Pain Specific No
Documents 12
Hot Single Events 15
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Inward rectifier potassium channel. They are ordered first by their pain relevance and then by number of times they were reported for Inward rectifier potassium channel. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT334594 Binding of GNAI1 and MRGPRD 1 0.01 0.19 0.63 5.00
2 INT334592 MRGPRD Positive_regulation of ABAT 1 0.03 0.32 0.54 5.00
3 INT231206 Binding of KCNH2 and KCNQ1 2 0.22 1.04 0.24 5.00
4 INT321578 Binding of Plaur and Positive_regulation of Ctsb 1 0.15 0.92 0.12 5.00
5 INT231223 Binding of KCNQ1 and Nav1 1 0.03 0.59 0.11 5.00
6 INT321580 Plaur Regulation of Ctsb 1 0.09 0.53 0 5.00
7 INT321581 Plaur Regulation of Mmp9 1 0.14 0.53 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Inward rectifier potassium channel. They are ordered first by their pain relevance and then by number of times they were reported in Inward rectifier potassium channel. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT102586 Negative_regulation of Kcnj8 2 0.42 0.68 0.5 98.04
2 INT113022 Negative_regulation of Med23 1 0.24 0.19 0.29 97.36
3 INT279524 Protein_catabolism of Adora1 1 0.88 0.34 0.38 96.08
4 INT279523 Positive_regulation of Protein_catabolism of Adora1 1 0.50 0.34 0.38 96.08
5 INT94408 Positive_regulation of Gene_expression of IFI27 28 0.65 12.89 3.53 93.64
6 INT80420 Gene_expression of IFI27 145 0.78 63.61 8.83 92.72
7 INT18059 Binding of GRIN2A 4 0.36 1.53 2.72 91.92
8 INT9377 Positive_regulation of Positive_regulation of TRPV1 43 0.70 15.81 24.47 91.24
9 INT9381 Positive_regulation of TRPV1 523 0.70 187.4 276.05 90.20
10 INT195982 Gene_expression of Atp1a2 5 0.65 1.54 3.19 86.88
11 INT101120 Gene_expression of Comt 63 0.77 34.75 26.13 86.88
12 INT195971 Gene_expression of Gabra2 7 0.75 2.08 3.88 86.88
13 INT163528 Gene_expression of Gabra1 3 0.74 0.75 2.73 86.88
14 INT195966 Gene_expression of Syt4 1 0.74 1.47 0.77 86.88
15 INT40160 Positive_regulation of Adora1 74 0.70 26.36 33.03 83.44
16 INT30168 Gene_expression of Dnahc8 20 0.65 4.17 1.73 75.84
17 INT334615 Gene_expression of MRGPRD 1 0.70 3.6 6.49 75.12
18 INT321560 Negative_regulation of Plaur 14 0.46 13.02 0.03 67.76
19 INT93129 Negative_regulation of KCNH2 42 0.54 9.63 10.85 66.80
20 INT195975 Transcription of Atp1a2 1 0.69 1.05 2.1 61.96
21 INT12476 Negative_regulation of TRPV1 124 0.59 47.95 77.98 55.68
22 INT101563 Transcription of Kcnj9 2 0.63 0.71 0.49 50.96
23 INT16654 Gene_expression of Insrr 138 0.46 58.96 75.68 32.96
24 INT95787 Positive_regulation of Mapk1 568 0.70 226.51 220.94 31.12
25 INT206471 Positive_regulation of Ptk2 34 0.51 25.75 1.61 31.12
26 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34 27.56
27 INT76249 Gene_expression of Gria1 67 0.75 15.07 22.78 13.72
28 INT79682 Gene_expression of Grm7 6 0.75 4.74 4.5 13.72
29 INT134208 Negative_regulation of Ptk2 19 0.58 23.59 0.52 8.20
30 INT98456 Negative_regulation of Src 17 0.42 8.3 0.42 8.20
31 INT321546 Negative_regulation of Pxn 3 0.10 0.72 0.11 8.20
32 INT321565 Negative_regulation of Angptl2 1 0.18 1.1 0 8.20
33 INT321562 Negative_regulation of Nexn 1 0.01 0.22 0 8.20
34 INT18981 Gene_expression of ABAT 78 0.68 38.35 61.36 5.00
35 INT96937 Gene_expression of Mmp9 191 0.75 150.3 56.01 5.00
36 INT16455 Gene_expression of Drd2 116 0.78 22.71 38.47 5.00
37 INT666 Gene_expression of Jun 124 0.78 54.61 33.67 5.00
38 INT15174 Gene_expression of Itgam 238 0.73 104.92 29.26 5.00
39 INT6782 Gene_expression of SCN5A 156 0.78 33.13 17.88 5.00
40 INT95767 Negative_regulation of Mmp9 72 0.57 49.14 17.1 5.00
41 INT125947 Gene_expression of Adora2b 57 0.75 23.69 17 5.00
42 INT1556 Regulation of Dnahc8 20 0.61 3.23 14.44 5.00
43 INT108063 Gene_expression of Adora2a 29 0.78 13.11 13.78 5.00
44 INT82854 Gene_expression of MRGPRX1 61 0.75 10.14 10.65 5.00
45 INT114406 Gene_expression of Adora1 28 0.72 6.83 9.13 5.00
46 INT64816 Transcription of Jun 31 0.69 16.01 7.64 5.00
47 INT101121 Regulation of Comt 19 0.53 10.66 7.22 5.00
48 INT195969 Binding of Khdrbs1 1 0.36 1.62 7.19 5.00
49 INT134967 Gene_expression of Ecm1 66 0.29 38.4 7.16 5.00
50 INT40159 Negative_regulation of Adora1 13 0.51 3.51 7.13 5.00
51 INT168600 Binding of Mmp9 14 0.44 12.79 6.92 5.00
52 INT86600 Gene_expression of KCNH2 37 0.78 14.88 6.14 5.00
53 INT73179 Gene_expression of Hspa1b 10 0.73 6.24 6.04 5.00
54 INT179810 Protein_catabolism of Ecm1 30 0.11 18.28 5.75 5.00
55 INT127276 Gene_expression of Slurp1 12 0.59 4.99 5.73 5.00
56 INT111384 Gene_expression of Adora3 18 0.75 10.53 5.73 5.00
57 INT23598 Binding of SCN5A 32 0.40 16 5.35 5.00
58 INT61252 Negative_regulation of Gene_expression of Itgam 38 0.54 16.48 5.01 5.00
59 INT15001 Localization of Gfap 29 0.75 6.71 4.1 5.00
60 INT16478 Positive_regulation of Plg 29 0.45 18.07 4.07 5.00
61 INT160915 Regulation of Mmp9 16 0.35 10.25 4.07 5.00
62 INT107415 Regulation of Kcnj9 6 0.62 1 3.87 5.00
63 INT99509 Gene_expression of CFLAR 25 0.75 22.59 3.78 5.00
64 INT172198 Protein_catabolism of Comt 7 0.88 2.78 3.6 5.00
65 INT67468 Regulation of SCN5A 27 0.44 4.4 3.47 5.00
66 INT195964 Transcription of Comt 8 0.71 4.72 3.4 5.00
67 INT171233 Binding of Ecm1 25 0.07 12.41 3.36 5.00
68 INT163066 Transcription of Gfap 12 0.69 4.47 3.21 5.00
69 INT136266 Gene_expression of KCNQ1 23 0.64 8.34 3.11 5.00
70 INT105985 Transcription of Mmp9 11 0.66 8.55 3.02 5.00
71 INT92189 Positive_regulation of Slurp1 4 0.18 1.84 3.01 5.00
72 INT14872 Gene_expression of TGFB3 15 0.55 12.45 2.96 5.00
73 INT50535 Gene_expression of CA3 25 0.51 9.25 2.89 5.00
74 INT195978 Gene_expression of Hsp90b1 26 0.65 11.28 2.88 5.00
75 INT73175 Positive_regulation of Gene_expression of Hspa1b 3 0.48 2.53 2.72 5.00
76 INT215601 Regulation of Positive_regulation of Adora1 9 0.60 1.74 2.66 5.00
77 INT194495 Regulation of Transcription of Jun 4 0.26 2.85 2.6 5.00
78 INT111298 Gene_expression of ACTN4 12 0.70 9.42 2.6 5.00
79 INT334607 Binding of MRGPRD 1 0.34 1.5 2.59 5.00
80 INT215599 Positive_regulation of Positive_regulation of Adora1 7 0.47 2.29 2.58 5.00
81 INT86602 Binding of KCNH2 14 0.36 4.65 2.58 5.00
82 INT92316 Gene_expression of Plaur 30 0.61 22.06 2.21 5.00
83 INT215611 Negative_regulation of Positive_regulation of Adora1 6 0.43 1.18 2.16 5.00
84 INT17688 Positive_regulation of IKZF1 5 0.50 0.48 2.11 5.00
85 INT195968 Positive_regulation of Gene_expression of Hsp90b1 10 0.49 5.21 2.02 5.00
86 INT117980 Regulation of Rac1 10 0.45 3.72 1.88 5.00
87 INT184031 Gene_expression of Cish 14 0.49 9.82 1.86 5.00
88 INT115850 Localization of Mtap2 10 0.73 3.68 1.76 5.00
89 INT79683 Negative_regulation of Grm7 3 0.41 2.22 1.75 5.00
90 INT168519 Positive_regulation of Gene_expression of Adora1 4 0.61 0.75 1.75 5.00
91 INT565 Negative_regulation of Cfb 18 0.13 6.77 1.69 5.00
92 INT195970 Binding of Atp1a2 2 0.34 2.31 1.66 5.00
93 INT146943 Gene_expression of Src 13 0.49 6.65 1.65 5.00
94 INT140058 Regulation of Cish 17 0.37 8.69 1.58 5.00
95 INT115463 Positive_regulation of Plau 13 0.47 8.47 1.49 5.00
96 INT241721 Positive_regulation of Transcription of Adora1 3 0.50 1.39 1.41 5.00
97 INT119221 Regulation of Slurp1 3 0.44 2.36 1.39 5.00
98 INT79681 Localization of Grm7 5 0.78 2.57 1.34 5.00
99 INT241737 Transcription of Adora1 3 0.72 0.89 1.32 5.00
100 INT195977 Transcription of Hsp90b1 5 0.56 1.74 1.27 5.00
101 INT130323 Regulation of Grm7 3 0.26 1.9 1.21 5.00
102 INT19803 Gene_expression of Hprt 15 0.67 4.81 1.03 5.00
103 INT195981 Transcription of Mtap2 1 0.52 0.53 0.99 5.00
104 INT210571 Gene_expression of KCNE2 7 0.61 2.7 0.97 5.00
105 INT195946 Gene_expression of Hprt1 9 0.75 1.03 0.89 5.00
106 INT195967 Negative_regulation of Gene_expression of Gnb1l 1 0.01 0.22 0.82 5.00
107 INT195980 Gene_expression of Gnb1l 1 0.02 0.22 0.82 5.00
108 INT334616 Positive_regulation of MRGPRD 1 0.63 0.26 0.81 5.00
109 INT134207 Gene_expression of Ptk2 56 0.73 31.97 0.78 5.00
110 INT195983 Localization of Comt 2 0.74 0.93 0.76 5.00
111 INT132662 Binding of Hcm 11 0.31 14.41 0.73 5.00
112 INT52590 Transcription of SCN5A 4 0.55 0.91 0.65 5.00
113 INT195976 Gene_expression of Aldh1a1 26 0.75 14.23 0.6 5.00
114 INT195984 Localization of LARS 3 0.42 0.93 0.53 5.00
115 INT334614 Regulation of MRGPRD 1 0.35 0.07 0.53 5.00
116 INT86601 Positive_regulation of KCNH2 7 0.49 1.56 0.52 5.00
117 INT98065 Binding of Plau 5 0.12 2.39 0.52 5.00
118 INT279525 Negative_regulation of Transcription of Adora1 1 0.43 0.26 0.51 5.00
119 INT125863 Regulation of CFLAR 3 0.28 1.66 0.48 5.00
120 INT200401 Gene_expression of KCNE1 14 0.57 6.42 0.45 5.00
121 INT192006 Gene_expression of RYR2 5 0.23 7.69 0.44 5.00
122 INT175299 Positive_regulation of Binding of Mmp9 2 0.28 1.17 0.42 5.00
123 INT149119 Binding of CFLAR 3 0.17 0.51 0.42 5.00
124 INT207081 Binding of Plaur 6 0.31 5.99 0.41 5.00
125 INT195979 Gene_expression of Aldh7a1 1 0.72 0.59 0.41 5.00
126 INT271521 Phosphorylation of Ptk2 10 0.59 11.45 0.39 5.00
127 INT334619 Positive_regulation of Gene_expression of MRGPRD 1 0.39 0.07 0.38 5.00
128 INT269825 Negative_regulation of Transcription of Mmp9 2 0.27 1.61 0.36 5.00
129 INT195974 Regulation of Atp1a2 1 0.43 0.44 0.29 5.00
130 INT166574 Positive_regulation of Plaur 6 0.56 3.52 0.29 5.00
131 INT136267 Binding of KCNQ1 3 0.36 3.28 0.28 5.00
132 INT334611 Regulation of Gene_expression of MRGPRD 1 0.21 0.07 0.25 5.00
133 INT166575 Regulation of Plaur 5 0.48 4 0.23 5.00
134 INT230722 Regulation of Hcm 4 0.37 3 0.21 5.00
135 INT195965 Localization of Kcnj9 1 0.64 0.18 0.21 5.00
136 INT321550 Gene_expression of Pxn 5 0.18 2.08 0.21 5.00
137 INT235549 Gene_expression of Ctsb 19 0.58 8.61 0.2 5.00
138 INT195972 Localization of Atp1a2 1 0.63 0.17 0.2 5.00
139 INT231220 Localization of ANK2 1 0.40 0.91 0.17 5.00
140 INT241326 Gene_expression of Kcnn4 2 0.48 0.06 0.17 5.00
141 INT334610 Transcription of MRGPRD 1 0.65 0 0.17 5.00
142 INT321547 Transcription of Plaur 2 0.56 1.02 0.13 5.00
143 INT269240 Regulation of Ptk2 6 0.42 2.84 0.13 5.00
144 INT231217 Positive_regulation of ANK2 1 0.26 0.67 0.12 5.00
145 INT321564 Positive_regulation of Protein_catabolism of Ctsb 1 0.16 0.92 0.12 5.00
146 INT193632 Positive_regulation of ARVD4 2 0.01 2.73 0.11 5.00
147 INT321559 Regulation of Protein_catabolism of Ctsb 1 0.10 0.89 0.11 5.00
148 INT283560 Negative_regulation of Gene_expression of Ptk2 6 0.40 4.84 0.09 5.00
149 INT231161 Gene_expression of Vcl 3 0.26 0.77 0.08 5.00
150 INT321566 Protein_catabolism of Ctsb 2 0.23 1.07 0.06 5.00
151 INT334620 Positive_regulation of Gene_expression of PEA15 1 0.11 0 0.06 5.00
152 INT334612 Positive_regulation of PEA15 1 0.11 0 0.05 5.00
153 INT189077 Gene_expression of PEA15 3 0.28 0.71 0.05 5.00
154 INT192016 Localization of RYR2 5 0.25 4.18 0.05 5.00
155 INT201155 Regulation of Jph2 2 0.37 1.13 0.05 5.00
156 INT221865 Positive_regulation of Localization of RYR2 2 0.15 4.56 0.05 5.00
157 INT219773 Gene_expression of Nexn 4 0.58 0.74 0.04 5.00
158 INT231205 Negative_regulation of Binding of Hcm 1 0.03 0.87 0.04 5.00
159 INT231221 Gene_expression of Prkag2 1 0.07 0.94 0.03 5.00
160 INT195973 Regulation of Gene_expression of Hprt 1 0.52 0.1 0.03 5.00
161 INT321555 Negative_regulation of Vcl 3 0.12 2.41 0.03 5.00
162 INT231222 Gene_expression of Lamp2 1 0.07 0.93 0.03 5.00
163 INT195947 Regulation of Gene_expression of Hprt1 1 0.44 0.1 0.03 5.00
164 INT321574 Regulation of ACTN4 1 0.01 0.52 0 5.00
165 INT321548 Negative_regulation of Ctsb 7 0.21 8.92 0 5.00
166 INT321558 Negative_regulation of Tln1 1 0.01 0.89 0 5.00
167 INT321573 Negative_regulation of ACTN4 1 0.01 0.67 0 5.00
168 INT321551 Negative_regulation of Transcription of Plaur 1 0.46 0.18 0 5.00
169 INT321557 Negative_regulation of Gene_expression of Nexn 1 0.01 0.38 0 5.00
170 INT321543 Negative_regulation of Tln2 1 0.07 0.89 0 5.00
171 INT321561 Gene_expression of Angptl2 1 0.24 0.78 0 5.00
172 INT321567 Regulation of Angptl2 1 0.08 0.52 0 5.00
173 INT172787 Negative_regulation of Plau 2 0.11 1.46 0 5.00
174 INT321556 Negative_regulation of Transcription of Ctsb 1 0.15 0.18 0 5.00
175 INT321554 Regulation of Vcl 1 0.06 0.52 0 5.00
176 INT321545 Gene_expression of Tln1 2 0.07 0.92 0 5.00
177 INT302615 Transcription of Rac1 5 0.66 1.1 0 5.00
178 INT321544 Transcription of Ctsb 1 0.25 0.18 0 5.00
179 INT321549 Regulation of Tln2 1 0.03 0.52 0 5.00
180 INT321563 Gene_expression of Tln2 1 0.03 0.43 0 5.00
181 INT321541 Regulation of Tln1 1 0.00 0.52 0 5.00
182 INT321572 Negative_regulation of Gene_expression of ACTN4 1 0.01 0.35 0 5.00
183 INT278332 Regulation of Ctsb 3 0.22 2.06 0 5.00
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