P:Mechanotransduction

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pChart

Pain Term
Category Process
Synonyms None
Pain Specific No
Documents 106
Hot Single Events 161
Hot Interactions 14

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Mechanotransduction. They are ordered first by their pain relevance and then by number of times they were reported for Mechanotransduction. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT286568 Car2 Positive_regulation of Positive_regulation of Pkd1 1 0.03 0.16 0.09 100.00
2 INT286565 Pkd2 Positive_regulation of Positive_regulation of Pkd1 1 0.21 0.11 0.09 99.96
3 INT206619 Mtpn Positive_regulation of Igf1 1 0.04 0.17 0.05 99.40
4 INT89475 TGFB1 Positive_regulation of Gene_expression of PTHLH 3 0.61 3.64 0.21 99.28
5 INT343547 ROCK1 Positive_regulation of Gene_expression of PTHLH 1 0.15 0.2 0.2 98.68
6 INT343542 ROCK1 Positive_regulation of Positive_regulation of PTHLH 1 0.21 0 0.12 96.56
7 INT343538 TGFB1 Positive_regulation of Gene_expression of GLI2 1 0.08 0.2 0.05 95.36
8 INT149386 Binding of Lyn and TRPV4 1 0.40 1.14 0.91 95.28
9 INT208621 Binding of Prph and Nmbr 1 0.05 0.43 1.12 91.68
10 INT231677 Binding of CD47 and THBS1 1 0.18 0 0.16 90.84
11 INT206620 Gh1 Positive_regulation of Igf1 1 0.25 0.17 0.04 89.12
12 INT343540 Binding of PPP1R12A and MLC1 1 0.09 0.15 0.04 81.68
13 INT283858 Binding of PTK2 and APOA5 1 0.00 0.67 0.21 81.20
14 INT231676 Binding of CD47 and ITGA5 1 0.02 0.08 0.07 80.20
15 INT256063 Myd88 Positive_regulation of Gene_expression of Mcpt1 1 0.13 0.56 0.27 73.44
16 INT140802 Accn2 Regulation of Transcription of Accn1 1 0.24 0 0.36 68.72
17 INT343545 Binding of GLI2 and ROCK1 1 0.07 0.65 0.03 64.36
18 INT343537 ROCK1 Regulation of Gene_expression of PTHLH 1 0.08 0.09 0.03 62.04
19 INT283857 APOA5 Positive_regulation of Positive_regulation of MAPK1 1 0.00 0.6 0.22 61.84
20 INT343544 Negative_regulation of GLI2 Negative_regulation of Gene_expression of PTHLH 1 0.24 0.53 0.03 58.80
21 INT252857 Binding of F2rl1 and Trpa1 1 0.22 0.84 0.63 58.56
22 INT283860 APOA5 Negative_regulation of MAPK1 1 0.00 0.59 0.21 58.16
23 INT278265 Binding of Fgf2 and Smcp 1 0.03 0.26 0.14 55.84
24 INT252859 Binding of Ngf and Trpa1 1 0.19 0.84 0.62 55.20
25 INT261841 Mastl Positive_regulation of Trpa1 1 0.00 0.82 1.3 54.88
26 INT222023 Gpx3 Regulation of Mapk8 1 0.01 1.43 0.18 53.52
27 INT127320 Gpx3 Regulation of Akt1 2 0.00 3.11 0.53 53.12
28 INT343546 Negative_regulation of ROCK1 Negative_regulation of Gene_expression of PTHLH 1 0.16 3.28 0.03 51.64
29 INT222025 Gpx3 Regulation of EPHB2 1 0.01 1.41 0.18 50.32
30 INT77646 Binding of Ngf and Ntrk1 23 0.40 7.85 9.26 50.00
31 INT282065 Binding of Calca and Ngf 1 0.14 0.85 1.11 50.00
32 INT282063 Ngf Positive_regulation of Positive_regulation of Prkca 1 0.09 0.18 0.8 50.00
33 INT252858 C5 Negative_regulation of Positive_regulation of Trpa1 1 0.02 0.78 0.74 38.28
34 INT286563 Binding of Id2 and P1Ehs1 1 0.00 0.17 0.06 30.24
35 INT286591 Binding of PKD1 and Id2 1 0.07 0.17 0.06 30.24
36 INT286592 Binding of PKD1 and P1Ehs1 1 0.00 0.16 0.06 28.80
37 INT352930 Prkaca Regulation of Phosphorylation of TP53 1 0.13 1.02 0.26 18.00
38 INT352931 Prkaca Regulation of TP53 1 0.13 1.01 0.26 16.64
39 INT352893 PTGDS Regulation of TP53 1 0.16 1.02 0.26 16.64
40 INT260744 Binding of Ecm1 and Tlr2 1 0.00 0.45 0.39 14.00
41 INT260746 Binding of TLR4 and Ecm1 1 0.02 0.44 0.38 14.00
42 INT260747 Binding of TLR4 and Tlr2 1 0.05 0.44 0.38 11.12
43 INT120723 Positive_regulation of Trpv1 Positive_regulation of Localization of Calca 3 0.51 0.48 1.92 5.00
44 INT261831 Mapk1 Negative_regulation of Hspg2 1 0.00 1.26 1.42 5.00
45 INT221916 RPS3AP18 Negative_regulation of Positive_regulation of Trpa1 1 0.00 0.75 0.93 5.00
46 INT222024 Mapk8 Regulation of Mapk14 2 0.17 0.83 0.79 5.00
47 INT261834 Itpr3 Positive_regulation of Prkca 2 0.01 0.33 0.78 5.00
48 INT322128 Binding of Ca2 and Trpv4 1 0.03 1.1 0.75 5.00
49 INT213026 Hdl1 Positive_regulation of Nos3 5 0.16 7.92 0.73 5.00
50 INT261845 NGF Positive_regulation of Trpa1 1 0.04 0.73 0.71 5.00
51 INT261835 Camk2a Positive_regulation of Prkca 1 0.01 0.32 0.66 5.00
52 INT261832 Trpv1 Negative_regulation of Trpa1 1 0.10 0.58 0.64 5.00
53 INT261830 Hspg2 Negative_regulation of Trpa1 1 0.01 0.58 0.63 5.00
54 INT261828 Igf1 Regulation of Localization of Trpv2 1 0.02 1.04 0.58 5.00
55 INT203033 Cnr1 Regulation of Cnr2 1 0.15 0.29 0.56 5.00
56 INT352891 Binding of ROS1 and GOPC 1 0.09 1.34 0.53 5.00
57 INT352892 Binding of CAV1 and ITGA2 1 0.20 1.61 0.47 5.00
58 INT322131 Binding of Prkcg and Trpv4 1 0.04 0.75 0.46 5.00
59 INT261839 Binding of Car2 and Trpv1 1 0.03 0 0.45 5.00
60 INT221917 RPS3AP18 Negative_regulation of Positive_regulation of Trpv3 1 0.01 0.25 0.38 5.00
61 INT208623 Nmbr Positive_regulation of Prph 1 0.04 0.15 0.36 5.00
62 INT170773 Binding of P2RX3 and P2RX2 1 0.07 0.27 0.35 5.00
63 INT198970 GAPDH Negative_regulation of ADAMTS3 1 0.47 0 0.35 5.00
64 INT198971 GAPDH Negative_regulation of ADAMTS5 1 0.47 0 0.35 5.00
65 INT198969 GAPDH Negative_regulation of TIMP1 1 0.47 0 0.35 5.00
66 INT322129 Binding of Prkcg and Ca2 1 0.00 0.57 0.33 5.00
67 INT322133 Trpv4 Regulation of Ca2 1 0.04 0.16 0.33 5.00
68 INT352894 Negative_regulation of Binding of ROS1 and GOPC 1 0.08 0.67 0.28 5.00
69 INT322132 Binding of Mbp and Trpv4 1 0.11 0.39 0.27 5.00
70 INT322127 Binding of Mbp and Ca2 1 0.01 0.39 0.27 5.00
71 INT352895 Positive_regulation of Binding of ROS1 and GOPC 1 0.08 0.68 0.26 5.00
72 INT352890 Binding of PTGDS and ROS1 1 0.13 0.67 0.25 5.00
73 INT260739 Mapk14 Regulation of Positive_regulation of Sp1 1 0.01 1.06 0.25 5.00
74 INT260743 Mapk14 Regulation of Gene_expression of Il10 1 0.04 0.99 0.24 5.00
75 INT261842 Pla2g6 Positive_regulation of Trpm8 1 0.03 0 0.23 5.00
76 INT210990 Binding of KCNMA1 and PKDREJ 1 0.00 0.6 0.19 5.00
77 INT352896 PTGDS Positive_regulation of Gene_expression of ROS1 1 0.12 0.91 0.18 5.00
78 INT222022 Binding of Mmp8 and Mmp9 1 0.28 1.98 0.15 5.00
79 INT238331 PDGFA Regulation of Gene_expression of GOPC 1 0.04 0 0.14 5.00
80 INT238330 Binding of PDGFA and Regulation of Gene_expression of GOPC 1 0.06 0 0.14 5.00
81 INT238329 EGF Regulation of Negative_regulation of ADAMTS5 1 0.03 0 0.14 5.00
82 INT238338 Binding of EGF and Regulation of Gene_expression of GOPC 1 0.05 0 0.14 5.00
83 INT238333 Binding of PDGFA and Regulation of Gene_expression of ADAMTS1 1 0.06 0 0.14 5.00
84 INT238341 GOPC Regulation of Transcription of ADAMTS1 1 0.04 0 0.14 5.00
85 INT238337 EGF Regulation of Gene_expression of GOPC 1 0.03 0 0.14 5.00
86 INT238336 PDGFA Regulation of Negative_regulation of ADAMTS5 1 0.04 0 0.14 5.00
87 INT238334 GOPC Regulation of Transcription of ADAMTS5 1 0.04 0 0.14 5.00
88 INT238342 Binding of EGF and Regulation of Gene_expression of ADAMTS1 1 0.05 0 0.14 5.00
89 INT210993 Binding of SEA and PKDREJ 1 0.05 0.17 0.1 5.00
90 INT210992 Binding of KCNMA1 and SP3 1 0.00 0.17 0.1 5.00
91 INT210989 Binding of FSCN1 and SP3 1 0.00 0.17 0.1 5.00
92 INT241248 Binding of Pkd1 and Pkd2 3 0.22 1.52 0.1 5.00
93 INT256061 Gopc Positive_regulation of Gene_expression of Vcam1 1 0.18 0.29 0.1 5.00
94 INT256060 Gopc Positive_regulation of Vcam1 1 0.13 0.29 0.1 5.00
95 INT288219 Cigs1 Regulation of Nrgn 1 0.00 0.87 0.1 5.00
96 INT210988 Binding of SP3 and PKDREJ 1 0.01 0.17 0.1 5.00
97 INT210994 Binding of SEA and SP3 1 0.00 0.17 0.1 5.00
98 INT210991 Binding of FSCN1 and PKDREJ 1 0.00 0.17 0.1 5.00
99 INT238340 IL1B Positive_regulation of Gene_expression of ADAMTS4 1 0.03 0.16 0.07 5.00
100 INT322130 Trpv1 Positive_regulation of Positive_regulation of Trpv4 1 0.15 0.1 0.05 5.00
101 INT238332 TNF Positive_regulation of Gene_expression of ADAMTS4 1 0.07 0.07 0.05 5.00
102 INT283862 Binding of CALD1 and MYH14 1 0.02 0 0 5.00
103 INT322126 Binding of Trpv4 and Fig4 1 0.02 0 0 5.00
104 INT321781 Whrn Positive_regulation of Gopc 1 0.18 0 0 5.00
105 INT286566 Binding of Ctnnb1 and Cdh6 1 0.00 1 0 5.00
106 INT321770 Binding of Myo15 and Whrn 1 0.43 0.08 0 5.00
107 INT286562 Gene_expression of Pkd1 Positive_regulation of Ctnnb1 1 0.02 0.52 0 5.00
108 INT321783 Binding of Pi4kb and Gsn 1 0.03 0 0 5.00
109 INT278264 Gene_expression of Ntf3 Positive_regulation of Smcp 1 0.02 0.32 0 5.00
110 INT343541 PTHLH Positive_regulation of GYPA 1 0.03 0.95 0 5.00
111 INT286571 Binding of Prkd1 and Pkd1 1 0.05 0.76 0 5.00
112 INT321772 Binding of Myo7a and Twf2 1 0.00 0 0 5.00
113 INT321778 Binding of P4hb and Whrn 1 0.33 0.06 0 5.00
114 INT283863 Binding of MAPK1 and PTK2 1 0.12 0.97 0 5.00
115 INT283859 Binding of ACTN4 and TREH 1 0.00 1.61 0 5.00
116 INT283865 Binding of MAPK1 and APOA5 1 0.00 0.22 0 5.00
117 INT321773 Binding of Shbdp1 and Positive_regulation of Ablim1 1 0.01 0 0 5.00
118 INT283866 Binding of SVIL and APOA5 1 0.00 0.22 0 5.00
119 INT261833 Binding of Add3 and Trpv4 1 0.00 0.12 0 5.00
120 INT261838 Lyn Regulation of Trpv4 1 0.03 0.19 0 5.00
121 INT321771 Binding of P4hb and Gsn 1 0.31 0.38 0 5.00
122 INT321776 Whrn Regulation of Localization of Gsn 1 0.23 0.07 0 5.00
123 INT343548 GLI2 Positive_regulation of Gene_expression of PTHLH 1 0.28 0.94 0 5.00
124 INT286574 Gene_expression of Pkd1 Negative_regulation of Cdk2 1 0.10 0.09 0 5.00
125 INT286570 Pkd2 Positive_regulation of Binding of Pkd1 1 0.21 0.73 0 5.00
126 INT261840 Binding of Mtap7 and Trpv4 1 0.05 0.12 0 5.00
127 INT286501 Binding of PKD1 and LILRB1 1 0.01 1.07 0 5.00
128 INT261843 Lyn Regulation of Regulation of Trpv4 1 0.03 0.19 0 5.00
129 INT321780 Binding of Guk1 and Gsn 1 0.06 0 0 5.00
130 INT343549 GLI2 Positive_regulation of GYPA 1 0.05 0.95 0 5.00
131 INT286561 Binding of Ctnnb1 and Cdh2 1 0.00 1.06 0 5.00
132 INT286593 Binding of Pkd1 and GOPC 1 0.02 1.13 0 5.00
133 INT321779 Whrn Positive_regulation of Myo15 1 0.39 0 0 5.00
134 INT286589 Binding of PKHD1 and Pkd2 1 0.09 0.52 0 5.00
135 INT286567 Prkd1 Regulation of Ctnnb1 1 0.01 0.39 0 5.00
136 INT286573 Pkd2 Regulation of Pkd1 1 0.12 0.25 0 5.00
137 INT321775 Binding of Whrn and Gsn 1 0.46 0.42 0 5.00
138 INT286564 Pkd1 Regulation of Mtor 1 0.00 0.51 0 5.00
139 INT286569 Binding of Pkd1 and Tsc2 1 0.06 1.01 0 5.00
140 INT286590 Binding of ID2 and Pkd2 1 0.13 0.13 0 5.00
141 INT261844 Lyn Positive_regulation of Lyn Regulation of Trpv4 1 0.01 0.19 0 5.00
142 INT206621 Col1a1 Positive_regulation of Col3a1 1 0.00 0.28 0 5.00
143 INT321769 Binding of Shbdp1 and Ablim1 1 0.01 0 0 5.00
144 INT321766 Shbdp1 Positive_regulation of Ablim1 1 0.01 0 0 5.00
145 INT343539 GLI2 Regulation of PTHLH 1 0.15 0.25 0 5.00
146 INT286572 Binding of Ctnnb1 and Pkd1 1 0.02 0.96 0 5.00
147 INT286594 Binding of LILRB1 and Pkd1 1 0.01 1.07 0 5.00
148 INT283899 Binding of Ephb2 and APOA5 1 0.00 0.67 0 5.00
149 INT321767 Myo15 Positive_regulation of Gopc 1 0.16 0 0 5.00
150 INT261837 Binding of Aqp5 and Trpv4 1 0.05 0.17 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Mechanotransduction. They are ordered first by their pain relevance and then by number of times they were reported in Mechanotransduction. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT123584 Gene_expression of Trpa1 176 0.78 83 78.65 100.00
2 INT231684 Positive_regulation of Binding of P2RY2 2 0.22 0.13 0.16 100.00
3 INT197433 Gene_expression of MORF4L1 1 0.14 0.36 0.05 100.00
4 INT125870 Gene_expression of CD47 3 0.76 5.11 1.71 99.92
5 INT149387 Negative_regulation of Trpa1 55 0.59 21.91 28.31 99.84
6 INT250171 Localization of Myd88 4 0.72 1.95 0.88 99.84
7 INT269692 Regulation of Negative_regulation of Trpa1 1 0.45 0.17 1.39 99.84
8 INT197429 Gene_expression of TCF4 6 0.33 3.8 0.18 99.78
9 INT109430 Positive_regulation of Trpa1 119 0.70 44 49.14 99.74
10 INT206471 Positive_regulation of Ptk2 34 0.51 25.75 1.61 99.64
11 INT60126 Regulation of Trpv1 186 0.62 85.53 133.4 99.48
12 INT231687 Regulation of CD47 1 0.44 0.26 0.32 99.36
13 INT343558 Regulation of Positive_regulation of IL19 1 0.44 0 0.12 99.28
14 INT134752 Negative_regulation of Gene_expression of TIMP3 5 0.37 2.25 0.73 99.20
15 INT134753 Gene_expression of TIMP3 19 0.68 15.24 0.88 99.20
16 INT120432 Regulation of Trpa1 22 0.61 9.65 12.36 99.08
17 INT47644 Positive_regulation of Localization of AGT 4 0.45 1.24 1.2 99.00
18 INT104250 Positive_regulation of Gene_expression of SPP1 17 0.69 13.22 1.44 98.98
19 INT225264 Positive_regulation of IL19 4 0.49 1.58 0.34 98.98
20 INT146346 Negative_regulation of Gene_expression of Trpa1 15 0.59 11.76 8.83 98.88
21 INT37541 Gene_expression of SPP1 113 0.77 68.54 11.35 98.74
22 INT109431 Gene_expression of Trpa1 123 0.78 51.84 59.98 98.72
23 INT126484 Localization of Trpa1 15 0.80 4.08 6.64 98.72
24 INT398 Localization of AGT 45 0.78 16.97 11.54 98.64
25 INT171233 Binding of Ecm1 25 0.07 12.41 3.36 98.60
26 INT134964 Regulation of Ecm1 13 0.10 7.45 2.37 98.60
27 INT197491 Gene_expression of Myd88 32 0.74 14.59 5.29 98.48
28 INT71786 Phosphorylation of MAPK1 256 0.82 110.09 46.17 98.46
29 INT208611 Negative_regulation of Nmbr 1 0.23 0.59 1.44 98.44
30 INT185436 Gene_expression of ROCK1 5 0.52 6.85 0.29 98.24
31 INT17701 Gene_expression of PTHLH 103 0.78 64.23 8.85 98.20
32 INT64170 Gene_expression of GLI2 31 0.46 14.96 3.99 98.20
33 INT112174 Gene_expression of Trpv4 47 0.78 26.26 20.09 97.92
34 INT32760 Regulation of Gene_expression of PTHLH 4 0.51 6.32 1 97.80
35 INT241238 Positive_regulation of Pkd2 5 0.46 1.44 0.24 97.80
36 INT9196 Gene_expression of PTGS1 215 0.77 96.99 60.5 97.68
37 INT133889 Gene_expression of Adamts1 78 0.76 48.05 6.58 97.28
38 INT184436 Regulation of Gene_expression of Adamts1 6 0.60 9.53 0.62 97.28
39 INT127981 Gene_expression of Trpc1 25 0.77 10.51 11.67 97.16
40 INT127980 Gene_expression of Trpc3 13 0.75 2.53 3.52 97.16
41 INT150826 Positive_regulation of Pkd1 9 0.37 3.65 0.35 97.12
42 INT91914 Binding of Accn1 3 0.36 0.44 1.24 96.88
43 INT91915 Negative_regulation of Binding of Accn1 1 0.19 0 0.25 96.88
44 INT164229 Gene_expression of LECT1 8 0.67 3.08 0.96 96.80
45 INT198977 Negative_regulation of Gene_expression of LECT1 1 0.42 0.48 0.21 96.80
46 INT141185 Regulation of Ros1 30 0.24 20.73 8.88 96.52
47 INT147223 Negative_regulation of Ccl28 1 0.42 0 0.16 96.48
48 INT11659 Gene_expression of COL2A1 164 0.78 78.49 22.58 96.48
49 INT20552 Negative_regulation of Gene_expression of COL2A1 29 0.56 11.92 4.81 96.48
50 INT126560 Binding of P2RY2 12 0.44 6.43 3.4 96.44
51 INT36715 Gene_expression of Trpc4 50 0.68 4.18 11.13 96.20
52 INT127978 Gene_expression of Trpc5 58 0.67 3.11 10.21 96.20
53 INT9289 Gene_expression of Htr3a 15 0.75 4.43 6.69 96.12
54 INT93191 Gene_expression of Accn2 22 0.76 10.04 8.91 95.64
55 INT231685 Binding of CD47 12 0.47 1.55 0.73 95.52
56 INT145426 Positive_regulation of Ros1 185 0.56 106.76 27.21 95.48
57 INT149383 Binding of Lyn 1 0.36 1.14 0.91 95.28
58 INT60710 Gene_expression of Col7a1 217 0.78 113.2 35.2 94.96
59 INT156296 Regulation of Trpv4 20 0.45 7.84 4.86 94.96
60 INT148788 Binding of Csk 2 0.12 2.14 1.89 94.96
61 INT69158 Localization of IL4 48 0.71 31.3 11.98 94.68
62 INT261468 Binding of Snrpf 4 0.17 1.66 0.71 94.56
63 INT22194 Gene_expression of Xdh 20 0.75 10.03 2.83 94.44
64 INT69789 Binding of Fn1 13 0.36 5.08 2.18 94.32
65 INT174423 Gene_expression of Smcp 39 0.48 29.45 6.06 94.24
66 INT278253 Positive_regulation of Gene_expression of Smcp 3 0.29 1.24 0.39 94.24
67 INT134597 Binding of Trpa1 21 0.48 9.41 9.74 94.08
68 INT101168 Gene_expression of Tbpl1 23 0.75 10.88 5.38 93.84
69 INT207497 Binding of ap 4 0.14 0.53 0.57 93.64
70 INT142120 Gene_expression of Runx2 45 0.77 15.76 2.55 93.56
71 INT166715 Gene_expression of Sox9 16 0.65 6.39 0.92 93.56
72 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 93.56
73 INT64539 Gene_expression of Gpx3 14 0.58 9.42 3.64 93.56
74 INT159899 Localization of Trpa1 9 0.75 1.9 3.4 93.52
75 INT343560 Regulation of Transcription of IL11 1 0.05 0 0.11 93.40
76 INT62360 Positive_regulation of PTHLH 31 0.70 28.23 3.46 93.36
77 INT71789 Positive_regulation of MAPK1 396 0.70 234.44 89.27 93.24
78 INT117601 Positive_regulation of Trpa1 174 0.70 72.41 71.9 93.20
79 INT289467 Transcription of IL11 6 0.57 1.5 0.67 93.00
80 INT233113 Regulation of Trpm8 24 0.61 18.08 13.17 92.68
81 INT10374 Gene_expression of RARA 39 0.75 22.59 4.28 92.68
82 INT197045 Gene_expression of PPIB 6 0.70 2.32 0.05 92.68
83 INT79840 Binding of Itga2b 4 0.16 2.51 1.28 92.64
84 INT126534 Negative_regulation of ROCK1 18 0.49 14.32 1.13 92.56
85 INT208617 Binding of Nmbr 1 0.25 1.57 2.84 92.48
86 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18 92.48
87 INT14733 Positive_regulation of Gene_expression of TGFB1 71 0.69 49.89 22.2 92.48
88 INT231474 Binding of THBS1 4 0.34 2.04 0.16 92.40
89 INT56300 Negative_regulation of Gene_expression of TGFB1 13 0.41 4.87 3.5 92.28
90 INT202218 Positive_regulation of Aco1 4 0.27 12.31 1.06 91.88
91 INT133875 Gene_expression of POMT1 26 0.58 17.1 1.48 91.72
92 INT34927 Negative_regulation of Smc1b 2 0.25 0.49 0.09 91.68
93 INT47372 Regulation of ap 12 0.18 2.14 3.76 91.64
94 INT155780 Gene_expression of Mmp8 19 0.77 15.85 6.33 91.56
95 INT220861 Positive_regulation of Mmp8 14 0.50 12.21 4.6 91.56
96 INT231688 Localization of CD47 1 0.73 0 0.09 91.52
97 INT130111 Regulation of Positive_regulation of MAPK1 14 0.36 11.01 5.9 91.28
98 INT28817 Binding of TRPV4 6 0.39 3.92 2.59 91.28
99 INT130019 Regulation of Phosphorylation of MAPK1 6 0.49 3.6 1.5 91.28
100 INT17561 Localization of Car2 303 0.79 60.95 44.52 91.08
101 INT130502 Negative_regulation of Trpa1 17 0.59 5.75 8.06 90.92
102 INT14731 Positive_regulation of TGFB1 78 0.67 52.57 22.23 90.76
103 INT19995 Gene_expression of Prph 16 0.75 8.11 5.52 90.60
104 INT85968 Positive_regulation of Pecam1 19 0.69 29.04 7.5 90.56
105 INT124702 Positive_regulation of Trpv4 21 0.69 7.14 8.2 90.56
106 INT91462 Positive_regulation of Phosphorylation of MAPK1 99 0.67 40.28 18.99 90.44
107 INT62072 Negative_regulation of Gene_expression of PTHLH 3 0.43 4.45 0.85 90.40
108 INT208607 Gene_expression of Nmbr 1 0.41 0.44 0.89 90.40
109 INT211006 Binding of PKD1 6 0.22 2.69 0.05 90.20
110 INT106525 Phosphorylation of Akt1 436 0.82 183.81 47.82 90.16
111 INT106522 Negative_regulation of Phosphorylation of Akt1 65 0.58 34.44 7.83 90.16
112 INT17539 Positive_regulation of Igf1 68 0.69 28.47 13.02 89.12
113 INT221915 Positive_regulation of Localization of Trpa1 1 0.21 0.5 0.63 89.12
114 INT4863 Positive_regulation of ap 22 0.37 9.13 6.11 88.96
115 INT169926 Positive_regulation of Gopc 416 0.46 157.8 58.67 88.96
116 INT28215 Gene_expression of CDKN1A 196 0.76 113.9 18.3 88.56
117 INT268272 Binding of ITGAV 1 0.01 0.5 0.04 88.52
118 INT21793 Positive_regulation of Ngf 154 0.70 94.78 85.27 88.24
119 INT109316 Negative_regulation of Mapk8 72 0.59 50.59 17.24 88.24
120 INT222012 Negative_regulation of Map2k3 1 0.41 1.62 0.27 88.24
121 INT93192 Transcription of Accn2 5 0.52 4.63 4.79 87.84
122 INT258250 Positive_regulation of ROCK1 7 0.51 2.07 0.22 87.76
123 INT5333 Gene_expression of NPEPPS 45 0.65 26.34 15.25 87.60
124 INT58061 Gene_expression of Trpv1 1117 0.78 451.54 637.59 87.08
125 INT153164 Binding of TKCR 1 0.00 1.35 0.31 86.96
126 INT143357 Binding of Ros1 48 0.36 27.76 6 86.68
127 INT136190 Transcription of Accn1 5 0.61 2.75 2.24 86.64
128 INT12081 Localization of TGFB1 64 0.81 35.4 17.47 86.56
129 INT25989 Localization of Vip 31 0.68 10.53 10.35 86.56
130 INT6967 Regulation of KCNMA1 28 0.61 3.37 4.3 86.44
131 INT149385 Positive_regulation of TRPV4 11 0.69 7.22 6.02 86.32
132 INT940 Negative_regulation of Ptgs1 219 0.59 104.34 95.97 85.92
133 INT81086 Positive_regulation of Accn1 8 0.65 7.51 4.62 85.76
134 INT174434 Localization of Smcp 6 0.53 2.45 1.46 85.68
135 INT278254 Positive_regulation of Localization of Smcp 1 0.24 0 0.85 85.68
136 INT174446 Positive_regulation of Smcp 7 0.33 5.47 2.24 85.68
137 INT184223 Positive_regulation of Gene_expression of ADAMTS4 6 0.43 1.07 0.98 85.60
138 INT108394 Positive_regulation of ADAMTS4 5 0.49 1.65 1.78 85.60
139 INT115071 Positive_regulation of Accn3 14 0.70 16.56 14.24 85.36
140 INT173591 Gene_expression of ADAMTS4 7 0.48 3.65 4.8 85.04
141 INT140800 Negative_regulation of Gene_expression of Accn1 1 0.40 0.08 0.33 84.92
142 INT142752 Positive_regulation of Myd88 26 0.66 12.07 4.4 84.80
143 INT68290 Gene_expression of Accn1 32 0.73 7.36 11.23 84.28
144 INT62071 Positive_regulation of Gene_expression of PTHLH 13 0.70 19.32 1.73 84.24
145 INT169402 Binding of Trpv4 8 0.47 5.13 2.78 84.16
146 INT134036 Regulation of Gsk3b 4 0.60 1.42 1.15 84.00
147 INT32545 Localization of Gsk3b 9 0.07 2.88 1.11 84.00
148 INT336062 Regulation of Localization of Gsk3b 1 0.03 0.48 0.04 84.00
149 INT64173 Regulation of Gene_expression of GLI2 4 0.37 2.89 0.88 83.56
150 INT343555 Regulation of Gene_expression of ROCK1 1 0.15 1.02 0.04 83.56
151 INT151907 Binding of Ecm1 6 0.11 2.48 0.83 83.48
152 INT174028 Negative_regulation of ADAMTS5 10 0.19 3.18 1.99 82.72
153 INT46827 Negative_regulation of ADAMTS1 2 0.42 0.93 0.26 82.72
154 INT89103 Regulation of Gene_expression of TGFB1 15 0.56 8.11 4.37 82.44
155 INT46016 Gene_expression of Ngfr 69 0.77 41.22 19.8 81.92
156 INT50674 Gene_expression of PTGS2 459 0.78 253.33 118.51 81.88
157 INT55135 Positive_regulation of Gene_expression of PTGS2 137 0.70 80.32 38.46 81.88
158 INT208615 Positive_regulation of Nmbr 1 0.27 0.06 0.2 81.16
159 INT137135 Gene_expression of THBS1 28 0.75 11.55 2.45 80.92
160 INT82829 Gene_expression of COMP 104 0.78 57 9.81 80.52
161 INT321755 Regulation of Gsn 1 0.54 0.88 0.23 80.08
162 INT343553 Phosphorylation of PPP1R12A 1 0.17 0.16 0.04 79.20
163 INT120201 Gene_expression of Aco1 54 0.35 26.29 2.95 78.96
164 INT109821 Negative_regulation of Trpv4 19 0.55 6.86 3.98 78.72
165 INT32648 Gene_expression of Tyrp1 80 0.66 17.9 16.59 78.64
166 INT145177 Positive_regulation of Gene_expression of Tyrp1 5 0.30 3.31 1.46 78.64
167 INT343552 Gene_expression of LIMK1 1 0.65 0.15 0.04 78.32
168 INT192242 Phosphorylation of LIMK1 4 0.61 0.34 0.04 78.24
169 INT100126 Localization of Accn3 7 0.77 2.73 2.76 78.12
170 INT135892 Localization of Accn2 4 0.74 2.23 2.12 78.12
171 INT140798 Localization of Accn1 3 0.76 0.24 0.34 78.12
172 INT173592 Binding of COL5A2 32 0.33 9.14 2.48 77.88
173 INT56291 Gene_expression of Ros1 503 0.63 274.12 81.5 77.72
174 INT147220 Regulation of Gene_expression of Stoml1 1 0.17 0.1 0.34 77.28
175 INT147222 Negative_regulation of Stoml1 1 0.16 0.1 0.34 77.28
176 INT147221 Gene_expression of Stoml1 1 0.25 0.1 0.34 77.28
177 INT100124 Gene_expression of Accn3 38 0.78 30.02 23.63 76.80
178 INT208613 Localization of Nmbr 1 0.40 0.2 0.46 76.80
179 INT1781 Negative_regulation of Gh1 127 0.59 16.94 51.77 76.52
180 INT38731 Localization of Trpv1 138 0.81 52.73 90.49 76.08
181 INT50670 Gene_expression of CPOX 763 0.76 442.13 195.02 75.12
182 INT50673 Positive_regulation of Gene_expression of CPOX 156 0.54 97.31 37.03 75.12
183 INT37896 Positive_regulation of Gene_expression of PTGS1 37 0.67 17.28 9.27 75.12
184 INT60162 Gene_expression of Ie 41 0.58 23.77 1.52 75.00
185 INT60165 Positive_regulation of Gene_expression of Ie 7 0.10 3.5 0.37 75.00
186 INT70134 Negative_regulation of TXK 124 0.23 81.96 9.59 75.00
187 INT60164 Regulation of Gene_expression of Ie 4 0.08 2.04 0.67 75.00
188 INT60163 Negative_regulation of Gene_expression of Ie 3 0.09 1.55 0.13 75.00
189 INT105537 Regulation of Gene_expression of Igf1 15 0.58 6.97 3.23 74.80
190 INT321743 Binding of Gsn 1 0.42 1.41 0.12 74.80
191 INT8915 Gene_expression of Igf1 199 0.78 78.58 32.51 74.52
192 INT98498 Binding of Trpv1 75 0.48 33.67 44.4 74.40
193 INT283879 Gene_expression of SVIL 1 0.31 0.27 0.07 74.16
194 INT96271 Positive_regulation of Gene_expression of Mcpt1 30 0.53 21.34 11.06 72.80
195 INT174844 Binding of Fig4 81 0.41 18.03 12.87 72.40
196 INT75525 Negative_regulation of Positive_regulation of MAPK1 40 0.59 25.15 11.15 72.40
197 INT72182 Gene_expression of Mcpt1 167 0.75 123.7 52.15 72.32
198 INT7365 Binding of Gh1 17 0.37 2.83 3.54 70.68
199 INT208614 Positive_regulation of Gene_expression of Nmbr 1 0.27 0.06 0.25 70.68
200 INT9381 Positive_regulation of TRPV1 523 0.70 187.4 276.05 69.16
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