P:Morphine

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pChart

Pain Term
Category Drug
Synonyms None
Pain Specific Yes
Documents 33337
Hot Single Events 200
Hot Interactions 200

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Morphine. They are ordered first by their pain relevance and then by number of times they were reported for Morphine. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT85042 Binding of CCT6A and MAX 1 0.00 0 3.13 100.00
2 INT155891 Nps Negative_regulation of Positive_regulation of Casp3 1 0.27 0.17 3.48 100.00
3 INT85041 Binding of IGHG3 and MAX 1 0.00 0 2.09 100.00
4 INT2714 Pomc Positive_regulation of Localization of Prl 17 0.79 0.5 8.18 100.00
5 INT115690 Negative_regulation of Prkcg Negative_regulation of Gene_expression of Fos 1 0.47 0.72 3.63 100.00
6 INT143946 Binding of Pebp1 and Mastl 1 0.00 2.04 3.82 100.00
7 INT32656 Pomc Positive_regulation of Rbm39 1 0.08 0.42 2.84 100.00
8 INT1313 Pomc Positive_regulation of Prl 7 0.35 0 4.19 100.00
9 INT31439 Penk Positive_regulation of Localization of Prl 8 0.55 0.23 6.24 100.00
10 INT123899 Binding of CYP3A4 and UGT2B7 1 0.52 0 1.46 100.00
11 INT158964 FosB Negative_regulation of Creb1 1 0.21 0 2.07 100.00
12 INT221180 Binding of OPRM1 and Flna 1 0.09 0.22 12.65 100.00
13 INT293009 IRF6 Positive_regulation of Positive_regulation of CA2 1 0.04 0.66 1.49 100.00
14 INT293013 IL8 Positive_regulation of Positive_regulation of CA2 1 0.12 0.66 1.49 100.00
15 INT227152 Positive_regulation of Binding of Mop3 and Gpm6a 1 0.00 0 1.39 100.00
16 INT227151 Binding of Mop3 and Gpm6a 1 0.00 0 1.38 100.00
17 INT31440 Penk Positive_regulation of Prl 7 0.76 0 4.1 100.00
18 INT60867 Binding of G2e3 and Gpm6a 2 0.01 0.1 1.93 100.00
19 INT88730 Binding of OPRM1 and Mop3 1 0.00 0 2.34 100.00
20 INT85040 Positive_regulation of Binding of CCT6A and MAX 1 0.00 0 1.06 100.00
21 INT85039 Binding of GPM6A and MAX 1 0.00 0 1.05 100.00
22 INT146512 Tmem132a Negative_regulation of Gene_expression of Fos 1 0.23 0 1.76 100.00
23 INT32586 H2-Ab1 Regulation of Pomc 1 0.03 0.14 2.19 100.00
24 INT32657 Positive_regulation of Pomc Positive_regulation of Rbm39 1 0.08 0.22 1.51 100.00
25 INT20456 Binding of Pomc and Penk 9 0.41 0.26 3.93 100.00
26 INT85252 Negative_regulation of Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.26 100.00
27 INT85251 Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.25 100.00
28 INT142413 Oprm1 Positive_regulation of Gdnf 1 0.19 0.29 1.09 100.00
29 INT106750 Pes1 Negative_regulation of Positive_regulation of Casp3 3 0.23 0 2.35 100.00
30 INT155890 Nps Negative_regulation of Gene_expression of Casp3 1 0.27 0.05 1.15 100.00
31 INT154226 Positive_regulation of Oprk1 Negative_regulation of Negative_regulation of Oprm1 1 0.28 0.07 2.32 100.00
32 INT155894 Nps Regulation of Gene_expression of Casp3 1 0.33 0.07 1.09 100.00
33 INT150682 Pomc Regulation of Gene_expression of Eif2ak3 1 0.37 0.17 1.44 100.00
34 INT106753 Pes1 Negative_regulation of Gene_expression of Casp3 2 0.12 0 2.19 100.00
35 INT60993 Ntf4 Negative_regulation of Positive_regulation of CRTAC1 1 0.00 0 1.37 100.00
36 INT159238 H2-M3 Negative_regulation of Gpm6a Positive_regulation of Casp3 1 0.01 0 1.14 100.00
37 INT211748 Binding of Pag1 and Mors1 2 0.07 0.2 2.26 100.00
38 INT25239 Ugt1a2 Positive_regulation of Ugt2b 1 0.30 0 0.85 100.00
39 INT29093 Binding of H2-Ab1 and Rbm39 1 0.06 0 1.5 100.00
40 INT112607 DNAJC15 Negative_regulation of Positive_regulation of Casp3 1 0.03 0.14 1.12 100.00
41 INT112608 DNAJC15 Regulation of Gene_expression of Fos 1 0.02 0.14 1.12 100.00
42 INT146587 Npff Negative_regulation of Positive_regulation of Casp3 1 0.05 0.18 1.92 100.00
43 INT146586 Npff Negative_regulation of Gene_expression of Casp3 1 0.06 0.18 1.92 100.00
44 INT159237 Gpm6a Positive_regulation of Casp3 1 0.03 0 1.07 100.00
45 INT318473 Positive_regulation of OPRM1 Positive_regulation of CA2 1 0.17 0.46 2.13 100.00
46 INT168609 Binding of Itgb1 and Mmp9 1 0.02 0.41 1.58 100.00
47 INT168608 Binding of Grin2b and Mmp9 1 0.22 0.41 1.57 100.00
48 INT168611 Binding of Mmp9 and Ndor1 1 0.29 0.41 1.57 100.00
49 INT63939 Vta1 Positive_regulation of Th 1 0.14 0 1.61 100.00
50 INT74460 GTS Negative_regulation of Casp3 1 0.04 0.37 1.08 100.00
51 INT79021 Regulation of Binding of Jun and Fos 2 0.50 0.66 1.5 100.00
52 INT36682 Gh1 Regulation of Gene_expression of Gnrhr 2 0.08 0 0.96 100.00
53 INT8734 Pebp1 Positive_regulation of Oprd1 1 0.01 0 1.54 100.00
54 INT36683 Gh1 Regulation of Gnrhr 3 0.08 1.25 0.95 100.00
55 INT65254 LOC100360318 Regulation of Gene_expression of Basp1 1 0.00 0.05 1.11 100.00
56 INT155893 Nps Regulation of Casp3 1 0.24 0.08 0.95 100.00
57 INT166360 Negative_regulation of Crhr1 Negative_regulation of Positive_regulation of Pomc 1 0.02 0.36 1.5 100.00
58 INT169218 Binding of EGFR and Coc 1 0.06 2.8 5.85 100.00
59 INT31438 Penk Positive_regulation of Localization of Pomc 1 0.18 0 1.9 100.00
60 INT129953 Oprd1 Regulation of Cspg5 1 0.17 0.15 1.74 100.00
61 INT201241 Positive_regulation of GDI2 Positive_regulation of Regulation of AGFG1 1 0.01 0 0.82 100.00
62 INT131887 Nr3c1 Regulation of Gene_expression of Prkcg 1 0.01 0 1.17 100.00
63 INT67809 Ugt2b1 Negative_regulation of Ugt2b7 1 0.47 0 0.7 100.00
64 INT137657 Gorasp2 Regulation of Binding of Casp3 1 0.09 0 1.52 100.00
65 INT103725 Negative_regulation of Oprd1 Positive_regulation of Gtpbp4 1 0.17 0.38 1.65 100.00
66 INT104749 Ugt1a1 Regulation of Positive_regulation of G2e3 1 0.00 0.07 0.77 100.00
67 INT104748 Ugt1a1 Regulation of Positive_regulation of LOC100359830 1 0.01 0.07 0.77 100.00
68 INT93435 Binding of Casp3 and Cckbr 1 0.06 0.15 1.18 100.00
69 INT61675 Binding of Gpm6a and Man2a2 1 0.00 0.08 1.67 100.00
70 INT8735 Oprm1 Positive_regulation of Scn4a 1 0.00 0 1.49 100.00
71 INT131889 gr Regulation of Gene_expression of Grin1 1 0.02 0 1.01 100.00
72 INT145407 Oprd1 Regulation of Positive_regulation of Dbi 1 0.17 0 1.07 100.00
73 INT13619 Acyp2-ps1 Negative_regulation of Localization of Prl 1 0.13 0 0.63 100.00
74 INT13618 Acyp2-ps1 Negative_regulation of Localization of Ggh 1 0.07 0 0.62 100.00
75 INT293011 GPM6A Regulation of GOPC 1 0.00 0 0.81 100.00
76 INT48032 Binding of Avp and Pebp1 1 0.00 0 0.68 100.00
77 INT127133 Positive_regulation of OPRM1 Positive_regulation of Protein_catabolism of SUCLG2 1 0.20 0.2 1.1 100.00
78 INT48031 Binding of Oxt and Pebp1 1 0.01 0 0.68 100.00
79 INT28387 Pomc Positive_regulation of Localization of LH 2 0.40 0.28 2.07 100.00
80 INT131574 Negative_regulation of Ephb1 Negative_regulation of Gene_expression of Creb1 1 0.41 0.33 1.58 100.00
81 INT125845 Positive_regulation of Pag1 Positive_regulation of Gene_expression of Arrb2 1 0.09 0.46 1.48 100.00
82 INT123454 CNR1 Regulation of Fos 1 0.00 0.06 1.12 100.00
83 INT123455 CNR1 Regulation of Positive_regulation of Fos 1 0.00 0.06 1.12 100.00
84 INT123894 Binding of CYP3A4 and UGT2B7 Regulation of UGT2B7 1 0.33 0 0.56 100.00
85 INT26198 Positive_regulation of Crh Positive_regulation of Localization of POMC 1 0.38 0 0.7 100.00
86 INT132464 Ltf Negative_regulation of Positive_regulation of Nos1 1 0.33 0 1.03 100.00
87 INT123896 CYP2B6 Regulation of UGT2B7 1 0.42 0 0.53 100.00
88 INT61046 Oprm1 Positive_regulation of Gh1 1 0.21 0 0.89 100.00
89 INT61047 Oprm1 Positive_regulation of Localization of Gh1 1 0.29 0 0.89 100.00
90 INT93781 Racgap1 Positive_regulation of Positive_regulation of Gnptab 1 0.02 0.07 1.49 100.00
91 INT93783 Racgap1 Positive_regulation of Gnptab 1 0.02 0.07 1.49 100.00
92 INT61048 Oprm1 Positive_regulation of Localization of Prl 1 0.16 0 0.88 100.00
93 INT61045 Oprm1 Positive_regulation of Prl 1 0.16 0 0.88 100.00
94 INT153041 Positive_regulation of Binding of Gpm6a and LOC100359830 1 0.01 0 1.01 100.00
95 INT153042 Binding of Gpm6a and LOC100359830 1 0.01 0 1.01 100.00
96 INT153040 Binding of LOC100359830 and LOC100360318 1 0.00 0 1.01 100.00
97 INT153039 Binding of G2e3 and LOC100360318 1 0.00 0 1.01 100.00
98 INT155043 Vta1 Regulation of Gene_expression of Fos 1 0.08 0 0.95 100.00
99 INT73776 Regulation of Binding of GH1 and GHR 2 0.26 0.16 0.75 100.00
100 INT111129 Adarb1 Regulation of Gene_expression of Fos 1 0.09 0 0.79 100.00
101 INT42806 Binding of CCT6A and PENK 1 0.02 0 1.23 100.00
102 INT61698 G2e3 Regulation of Localization of Abat 1 0.05 0 0.88 100.00
103 INT165844 Binding of ATF4 and HSP90AB1 1 0.15 0.34 0.61 100.00
104 INT94630 Positive_regulation of Adarb1 Positive_regulation of Gene_expression of Fos 2 0.03 0.1 1.32 100.00
105 INT150679 Pomc Regulation of Gene_expression of Camk2a 1 0.30 0.07 0.79 100.00
106 INT128654 ITIH4 Regulation of Gene_expression of CCL16 1 0.02 2.69 1.79 100.00
107 INT31445 ENG Positive_regulation of Localization of Prl 4 0.01 0 1.77 100.00
108 INT36684 Gh1 Regulation of Prl 2 0.18 1.25 0.48 100.00
109 INT64259 Binding of Gtpbp4 and Ptprg 1 0.06 0 1.1 100.00
110 INT34220 Binding of POMC and Oprl1 4 0.01 0.25 4.05 100.00
111 INT46243 Binding of Ptger1 and Penk 1 0.01 0 0.77 100.00
112 INT50434 Binding of Oprm1 and Mop3 1 0.00 0 0.58 100.00
113 INT42780 Negative_regulation of Scn4a Negative_regulation of Positive_regulation of Prl 1 0.11 0 0.69 100.00
114 INT149741 Rf Negative_regulation of Qrfp 1 0.00 0.26 1.06 100.00
115 INT42779 Scn4a Positive_regulation of Localization of Gnrhr 1 0.10 0 0.66 100.00
116 INT107331 Binding of PPBP and Adarb1 1 0.01 0 3.67 100.00
117 INT123898 CYP3A4 Regulation of UGT2B7 1 0.22 0 0.41 100.00
118 INT52195 Sigmar1 Positive_regulation of Positive_regulation of Grin1 1 0.15 0 0.87 100.00
119 INT122823 ERCC2 Regulation of Negative_regulation of OPRM1 1 0.23 0.17 0.63 100.00
120 INT65256 Pebp1 Regulation of Gene_expression of Basp1 1 0.00 0.05 0.64 100.00
121 INT96796 ITIH4 Regulation of Gene_expression of OPRM1 2 0.20 0.89 1.41 100.00
122 INT63940 Negative_regulation of Vta1 Positive_regulation of Th 1 0.13 0 0.81 100.00
123 INT66408 Pomc Positive_regulation of Regulation of HRH1 1 0.01 0 1.58 100.00
124 INT31444 ENG Positive_regulation of Prl 1 0.01 0 1.14 100.00
125 INT42482 Binding of Cpe and Pebp1 1 0.02 0 0.95 100.00
126 INT31844 Grpr Regulation of Localization of Prl 1 0.04 0.37 0.47 100.00
127 INT61165 Binding of Pag1 and Pcyt1a 1 0.01 0.33 0.73 100.00
128 INT65255 Gpm6a Regulation of Gene_expression of Basp1 1 0.01 0 0.47 100.00
129 INT31843 Grpr Negative_regulation of Localization of Prl 1 0.03 0.34 0.34 100.00
130 INT1006 Sst Negative_regulation of Ggh 1 0.24 0 0.52 100.00
131 INT777 Prss12 Positive_regulation of Prl 1 0.19 0 1.33 100.00
132 INT34311 Regulation of CRH Positive_regulation of POMC 1 0.24 0 0.59 100.00
133 INT40311 Regulation of Binding of Pomc and Penk 1 0.23 0 0.64 100.00
134 INT30345 Pomc Regulation of Localization of Penk 3 0.31 0 2.61 100.00
135 INT150537 OPRM1 Positive_regulation of Negative_regulation of IL6 1 0.04 0.38 0.48 100.00
136 INT150536 OPRM1 Positive_regulation of Positive_regulation of IL6 1 0.04 0.38 0.48 100.00
137 INT150539 OPRM1 Positive_regulation of IL6 1 0.04 0.38 0.48 100.00
138 INT150534 OPRM1 Positive_regulation of TNF 1 0.03 0.38 0.48 100.00
139 INT150535 OPRM1 Positive_regulation of Positive_regulation of TNF 1 0.08 0.38 0.48 100.00
140 INT43839 Regulation of POMC Positive_regulation of PRL 1 0.32 0 0.28 100.00
141 INT43836 Regulation of POMC Positive_regulation of GHRH 1 0.14 0 0.28 100.00
142 INT59606 Binding of Tspo and Penk 1 0.04 0 1.12 100.00
143 INT42727 Binding of Oprm1 and Trim13 1 0.14 0 2.54 100.00
144 INT70288 Negative_regulation of Atxn2l Positive_regulation of Racgap1 1 0.02 0.3 1.19 100.00
145 INT128652 ITIH4 Regulation of Gene_expression of CCR5 1 0.36 1.46 0.93 100.00
146 INT128655 ITIH4 Regulation of Gene_expression of CCR3 1 0.36 1.45 0.92 100.00
147 INT128653 ITIH4 Regulation of Gene_expression of MIP 1 0.23 1.44 0.92 100.00
148 INT112399 Olr897-ps Regulation of Gene_expression of Casp3 1 0.03 0 0.54 100.00
149 INT31443 ENG Positive_regulation of Localization of Pomc 1 0.00 0 0.63 100.00
150 INT121873 Creb1 Regulation of Phosphorylation of Car2 1 0.10 0 0.62 100.00
151 INT90750 Oprd1 Regulation of Positive_regulation of Gpd1 1 0.10 0.25 0.78 100.00
152 INT39109 Binding of INSRR and PDYN 1 0.15 0.45 1.46 100.00
153 INT39108 Binding of PDYN and YY1 2 0.50 0.44 2.14 100.00
154 INT26677 Penk Regulation of Localization of Trh 5 0.50 0 3.05 100.00
155 INT318472 CA2 Regulation of OPRM1 1 0.17 0 0.51 100.00
156 INT1390 Trh Positive_regulation of Prl 14 0.67 4.42 4.39 100.00
157 INT775 Nts Positive_regulation of Gnrhr 2 0.18 0 1.02 100.00
158 INT780 Prss12 Positive_regulation of Gene_expression of Prl 1 0.14 0 0.65 100.00
159 INT781 Prss12 Positive_regulation of Gene_expression of Gnrhr 1 0.10 0 0.65 100.00
160 INT779 Nts Positive_regulation of Gene_expression of Gnrhr 1 0.28 0 0.65 100.00
161 INT776 Nts Positive_regulation of Gene_expression of Prl 1 0.36 0 0.65 100.00
162 INT773 Prss12 Positive_regulation of Gnrhr 1 0.04 0 0.64 100.00
163 INT774 Nts Positive_regulation of Prl 1 0.34 0 0.64 100.00
164 INT42521 Pomc Regulation of Dbi 1 0.06 0 0.17 100.00
165 INT148629 Binding of Cat and Casp3 1 0.08 0.09 0.26 100.00
166 INT10268 Binding of PDYN and POMC 11 0.39 0.08 10.36 100.00
167 INT29240 Binding of POMC and YY1 5 0.40 0.17 4.06 100.00
168 INT168229 Oprm1 Regulation of Cea 1 0.10 0.26 1.3 100.00
169 INT69338 Binding of Oprd1 and Oprm1 1 0.24 0.26 1.11 100.00
170 INT43454 Pomc Regulation of Localization of Avp 2 0.24 0.89 0.94 100.00
171 INT63859 Oprm1 Negative_regulation of Oprm1 1 0.10 0.08 0.86 100.00
172 INT63858 Oprm1 Negative_regulation of Penk 1 0.05 0.08 0.86 100.00
173 INT40826 Pomc Negative_regulation of Binding of Sstr1 1 0.05 0 0.74 100.00
174 INT53225 Qrfp Positive_regulation of Localization of LH 1 0.06 0 0.74 100.00
175 INT169215 Binding of OPRM1 and CARTPT 1 0.00 0.22 0.67 100.00
176 INT169217 Binding of Pebp1 and Coc 1 0.00 0.22 0.67 100.00
177 INT169219 Binding of OPRM1 and Coc 1 0.01 0.22 0.67 100.00
178 INT169213 Binding of EGFR and CARTPT 1 0.00 0.22 0.67 100.00
179 INT97916 Tinag Negative_regulation of Gene_expression of Fos 1 0.01 0.35 0.6 100.00
180 INT114009 Pomc Regulation of Binding of Crygs and Oprm1 1 0.03 0 0.56 100.00
181 INT64217 Oprm1 Positive_regulation of Oprd1 1 0.24 0 0.46 100.00
182 INT75728 PCDHB17 Positive_regulation of CCT6A 1 0.00 0.06 0.44 100.00
183 INT354984 Binding of Cacna1a and Tnf 1 0.01 0.83 0.4 100.00
184 INT156380 Regulation of Binding of Grin1 and Dlg4 1 0.29 0.32 0.97 99.98
185 INT137923 VEGFA Positive_regulation of Phosphorylation of Akt1 1 0.05 0 0.93 99.98
186 INT137921 VEGFA Positive_regulation of Ephb2 1 0.03 0 0.93 99.98
187 INT116610 Positive_regulation of Lnpep Regulation of Nos2 1 0.16 0.62 0.44 99.98
188 INT544 Binding of ALB and GC 1 0.13 0 0.55 99.98
189 INT83705 Acyp2-ps1 Regulation of Positive_regulation of Casp3 1 0.17 0 1.28 99.98
190 INT211747 Negative_regulation of Binding of Oprm1 and Mors1 1 0.09 0 1.86 99.98
191 INT146097 Positive_regulation of Binding of Rgs9 and Arrb2 1 0.28 0 1.04 99.98
192 INT227157 Binding of PEBP1 and Gpm6a 1 0.00 1.28 5.52 99.96
193 INT259228 Binding of Oprm1 and Glul 1 0.00 0.08 7.22 99.96
194 INT34294 Penk Positive_regulation of Localization of Crh 1 0.16 0.43 3.19 99.96
195 INT317551 Binding of Akt1 and Oprm1 1 0.19 0.21 2.74 99.96
196 INT11392 Cck Positive_regulation of Cckbr 1 0.52 0 0.96 99.96
197 INT42929 Pomc Negative_regulation of Localization of Oxt 1 0.11 0 0.76 99.96
198 INT114432 Oprl1 Positive_regulation of Akt1 1 0.18 0.08 2.2 99.96
199 INT94270 Pomc Regulation of Transcription of Crh 1 0.17 0.67 1.6 99.92
200 INT11613 Cck Positive_regulation of Localization of Oxt 3 0.53 0 4.17 99.92

Single Events

The table below shows the top 200 pain related interactions that have been reported for Morphine. They are ordered first by their pain relevance and then by number of times they were reported in Morphine. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02 100.00
2 INT158 Localization of Prl 2431 0.81 378.96 952.2 100.00
3 INT5202 Positive_regulation of Gene_expression of Fos 1163 0.70 319.28 684 100.00
4 INT5228 Positive_regulation of Fos 934 0.70 209.8 503.87 100.00
5 INT5895 Gene_expression of Oprm1 525 0.78 120.67 407.29 100.00
6 INT22548 Positive_regulation of Casp3 483 0.70 258.78 213.07 100.00
7 INT155 Positive_regulation of Prl 1233 0.70 317.93 457.82 100.00
8 INT157 Positive_regulation of Localization of Prl 790 0.70 104.54 374.78 100.00
9 INT11624 Gene_expression of OPRM1 445 0.78 72.36 294.36 100.00
10 INT65600 Positive_regulation of Casp3 376 0.70 198.44 128.03 100.00
11 INT5540 Positive_regulation of Oprm1 344 0.70 76.77 319.71 100.00
12 INT162 Regulation of Prl 794 0.62 165.01 322.24 100.00
13 INT161 Regulation of Localization of Prl 615 0.62 65.37 298.66 100.00
14 INT6056 Negative_regulation of Gene_expression of Fos 601 0.59 193.05 386.84 100.00
15 INT6406 Binding of Oprm1 280 0.48 40.54 226.26 100.00
16 INT5379 Gene_expression of Fos 656 0.78 255.5 292.54 100.00
17 INT14151 Gene_expression of Casp3 311 0.78 140.26 120.68 100.00
18 INT4941 Positive_regulation of Oprd1 345 0.70 74.26 304.41 100.00
19 INT5591 Regulation of Gene_expression of Fos 425 0.62 129.06 265.78 100.00
20 INT9131 Positive_regulation of Prkcg 431 0.70 130.8 302.41 100.00
21 INT886 Gene_expression of Pomc 676 0.78 129.87 295.98 100.00
22 INT12602 Negative_regulation of Oprm1 190 0.59 36.11 177.85 100.00
23 INT5501 Regulation of Oprd1 283 0.62 55.1 249.9 100.00
24 INT5660 Binding of Oprd1 477 0.48 71.86 342.06 100.00
25 INT26472 Regulation of Oprm1 191 0.62 35.84 173.1 100.00
26 INT767 Localization of Gnrhr 565 0.80 106.68 214.57 100.00
27 INT4768 Positive_regulation of OPRM1 212 0.70 31.09 164.28 100.00
28 INT1395 Negative_regulation of Penk 537 0.59 87.33 389.81 100.00
29 INT11009 Phosphorylation of Creb1 458 0.82 111.34 221.97 100.00
30 INT7327 Regulation of Th 164 0.62 29.67 110.14 100.00
31 INT796 Gene_expression of Penk 1902 0.78 275.47 1057.59 100.00
32 INT3948 Regulation of Cck 291 0.62 58.07 255.88 100.00
33 INT1665 Positive_regulation of Pag1 270 0.68 186.63 229.87 100.00
34 INT31116 Gene_expression of Casp3 192 0.78 78.21 57.43 100.00
35 INT1047 Negative_regulation of LH 314 0.59 53.71 135.89 100.00
36 INT1652 Regulation of Pomc 387 0.62 61.01 186.51 100.00
37 INT5513 Negative_regulation of Pomc 295 0.59 60.9 158.63 100.00
38 INT6293 Gene_expression of Oprm1 312 0.78 48.73 215.61 100.00
39 INT416 Regulation of LH 253 0.62 31.48 125.55 100.00
40 INT159 Negative_regulation of Localization of Prl 416 0.59 55.34 171.8 100.00
41 INT797 Regulation of Penk 812 0.62 111.13 542.24 100.00
42 INT5931 Regulation of Oprm1 149 0.62 18.15 125.93 100.00
43 INT2651 Positive_regulation of Pomc 403 0.70 95.72 206.24 100.00
44 INT156 Negative_regulation of Prl 542 0.59 131.97 192.24 100.00
45 INT2640 Gene_expression of Pomc 424 0.78 120.72 155.37 100.00
46 INT443 Localization of POMC 1020 0.81 284.52 443.17 100.00
47 INT22546 Positive_regulation of Gene_expression of Casp3 97 0.70 47.89 51.92 100.00
48 INT6042 Binding of Oprm1 248 0.48 31.77 154.34 100.00
49 INT83419 Gene_expression of Mors1 57 0.68 12.11 63.66 100.00
50 INT1396 Binding of Penk 355 0.48 22.79 269.65 100.00
51 INT880 Positive_regulation of Localization of Gh1 304 0.70 14.79 150.23 100.00
52 INT2106 Regulation of Localization of LH 279 0.62 22.37 122.77 100.00
53 INT2366 Binding of Cck 192 0.48 30.64 163.46 100.00
54 INT720 Positive_regulation of POMC 807 0.70 237.37 353.83 100.00
55 INT1902 Gene_expression of Cck 348 0.78 70.33 241.92 100.00
56 INT728 Positive_regulation of Penk 1068 0.70 186.9 636.87 100.00
57 INT1212 Binding of Oprl1 312 0.48 28.6 225.15 100.00
58 INT49552 Negative_regulation of Positive_regulation of Casp3 76 0.55 36.04 44.78 100.00
59 INT7341 Positive_regulation of Grin1 169 0.70 65.86 118.38 100.00
60 INT4937 Negative_regulation of Oprd1 224 0.59 44.51 171.11 100.00
61 INT1639 Negative_regulation of OPRM1 107 0.59 13.86 90.37 100.00
62 INT5587 Regulation of Fos 191 0.62 40.81 99.7 100.00
63 INT63932 Positive_regulation of Ephb1 537 0.70 259.67 296.14 100.00
64 INT339 Regulation of Trh 156 0.62 39.27 83.55 100.00
65 INT81417 Gene_expression of PAG1 94 0.58 90.85 92.79 100.00
66 INT57380 Phosphorylation of Creb1 213 0.82 66.8 71.26 100.00
67 INT65598 Negative_regulation of Positive_regulation of Casp3 45 0.59 18.36 28.59 100.00
68 INT5380 Positive_regulation of Gene_expression of Fos 243 0.70 105.65 131.05 100.00
69 INT27493 Negative_regulation of Casp3 114 0.56 56.89 44.63 100.00
70 INT108726 Binding of Mors1 38 0.33 7.08 43.62 100.00
71 INT1309 Positive_regulation of Localization of Gnrhr 152 0.69 24.25 81.56 100.00
72 INT875 Regulation of Localization of Gh1 166 0.62 12.87 84.97 100.00
73 INT4259 Positive_regulation of Npr1 262 0.70 49.37 123.11 100.00
74 INT67585 Gene_expression of UGT2B7 52 0.78 2.33 24.13 100.00
75 INT1414 Regulation of Oprl1 169 0.62 32.05 139.99 100.00
76 INT1898 Regulation of Crh 220 0.62 61.33 102.64 100.00
77 INT65597 Negative_regulation of Casp3 69 0.59 39.19 29.32 100.00
78 INT4658 Binding of OPRM1 188 0.48 25.96 136.24 100.00
79 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 100.00
80 INT9132 Negative_regulation of Prkcg 279 0.59 88.05 203.47 100.00
81 INT874 Positive_regulation of Gh1 244 0.70 27.17 97.98 100.00
82 INT6665 Gene_expression of FOS 520 0.77 165.31 217.66 100.00
83 INT11011 Positive_regulation of Phosphorylation of Creb1 190 0.70 49.25 112.01 100.00
84 INT62521 Phosphorylation of Oprm1 44 0.82 2.66 47.45 100.00
85 INT2056 Negative_regulation of Gnrh1 175 0.59 33.43 63.32 100.00
86 INT1308 Localization of Pomc 457 0.81 66.83 217.5 100.00
87 INT943 Negative_regulation of Cck 205 0.59 38.42 174.78 100.00
88 INT462 Regulation of Pomc 157 0.62 41.67 67.27 100.00
89 INT8733 Localization of Oprm1 61 0.75 7.55 64.61 100.00
90 INT69484 Positive_regulation of Gene_expression of OPRM1 75 0.70 12.86 52.27 100.00
91 INT79093 Positive_regulation of Nos1 101 0.70 46.89 59.61 100.00
92 INT6852 Localization of TNF 883 0.81 705.95 270.84 100.00
93 INT1044 Negative_regulation of Localization of LH 358 0.59 25.95 151.31 100.00
94 INT5590 Negative_regulation of Fos 144 0.59 40.94 81.98 100.00
95 INT2055 Regulation of Gnrh1 185 0.62 23.65 71.26 100.00
96 INT22516 Gene_expression of H2-M3 17 0.25 2.98 13.59 100.00
97 INT1437 Negative_regulation of Pomc 132 0.59 35.22 60.97 100.00
98 INT5061 Negative_regulation of Mme 306 0.59 51.97 136.9 100.00
99 INT7528 Regulation of OPRM1 100 0.62 20.63 80.57 100.00
100 INT148 Positive_regulation of Gnrhr 182 0.70 47.44 79.64 100.00
101 INT78694 Positive_regulation of Gene_expression of Casp3 46 0.66 18.64 19.62 100.00
102 INT6128 Positive_regulation of Localization of POMC 256 0.70 68.77 121.64 100.00
103 INT8732 Positive_regulation of Gene_expression of Oprm1 76 0.70 22.59 58.83 100.00
104 INT127341 Gene_expression of Gpm6a 44 0.75 3.67 13.32 100.00
105 INT28001 Gene_expression of Gpm6a 23 0.66 16.66 21.09 100.00
106 INT90313 Negative_regulation of Gene_expression of Casp3 57 0.57 22.23 26.77 100.00
107 INT74827 Positive_regulation of Gene_expression of Slc1a2 52 0.70 26.54 50.63 100.00
108 INT2159 Regulation of Localization of Gnrh1 200 0.62 13.28 99.07 100.00
109 INT7534 Gene_expression of Ifng 193 0.78 111.02 68.6 100.00
110 INT5610 Positive_regulation of Insr 140 0.69 37.26 86.24 100.00
111 INT203 Positive_regulation of Pomc 257 0.70 90.56 92.84 100.00
112 INT11807 Gene_expression of Il2 266 0.78 112 64.97 100.00
113 INT49170 Negative_regulation of Nos1 116 0.59 60.66 58.87 100.00
114 INT2862 Positive_regulation of Localization of Cck 108 0.70 20.75 94.25 100.00
115 INT738 Regulation of POMC 459 0.62 111.19 243.74 100.00
116 INT53385 Positive_regulation of Gene_expression of FosB 26 0.70 9.18 26.33 100.00
117 INT57021 Positive_regulation of Gene_expression of Grin1 62 0.70 24.77 47.31 100.00
118 INT4207 Regulation of Avp 267 0.62 63.72 115.33 100.00
119 INT48767 Negative_regulation of NOS1 312 0.59 154.25 90.32 100.00
120 INT114 Binding of Oprl1 139 0.48 23 103.35 100.00
121 INT739 Negative_regulation of POMC 358 0.59 102.28 166.77 100.00
122 INT6436 Positive_regulation of Positive_regulation of Fos 101 0.70 18.71 57.96 100.00
123 INT60865 Gene_expression of G2e3 20 0.73 2.1 12.76 100.00
124 INT5507 Regulation of Localization of Crh 57 0.61 8.43 30.26 100.00
125 INT64110 Positive_regulation of Gene_expression of Nos1 68 0.70 58.11 51.64 100.00
126 INT55874 Binding of GPM6A 20 0.34 4.2 13.63 100.00
127 INT31186 Negative_regulation of Insrr 81 0.37 24.91 55.94 100.00
128 INT51698 Positive_regulation of Gene_expression of Prkcg 44 0.68 14.02 32.9 100.00
129 INT31774 Positive_regulation of Vta1 67 0.44 14.52 71.79 100.00
130 INT619 Positive_regulation of Positive_regulation of Prl 116 0.70 22.69 45.06 100.00
131 INT16654 Gene_expression of Insrr 138 0.46 58.96 75.68 100.00
132 INT6669 Negative_regulation of Positive_regulation of Fos 98 0.59 23.5 56.82 100.00
133 INT5514 Negative_regulation of Localization of Crh 64 0.58 8.12 29.29 100.00
134 INT80470 Negative_regulation of Gene_expression of Grin1 33 0.59 10.22 27.15 100.00
135 INT770 Regulation of Localization of Gnrhr 127 0.61 17.91 58.23 100.00
136 INT17459 Positive_regulation of Gene_expression of FOS 182 0.67 53.45 96.38 100.00
137 INT8528 Negative_regulation of Gene_expression of Fos 100 0.59 41.15 55.6 100.00
138 INT56870 Gene_expression of CYP2D6 87 0.78 8.83 37.53 100.00
139 INT5770 Binding of Rbm39 88 0.41 13.23 55.5 100.00
140 INT58775 Binding of G2e3 10 0.33 0.19 11.52 100.00
141 INT8153 Regulation of Localization of Cck 52 0.62 11.22 54.83 100.00
142 INT1976 Regulation of Gene_expression of Prl 80 0.62 20.19 36 100.00
143 INT6822 Gene_expression of Pdyn 215 0.78 35.99 125.76 100.00
144 INT6979 Positive_regulation of CA2 206 0.67 50.79 44.97 100.00
145 INT1438 Localization of Pomc 360 0.81 101.26 116.47 100.00
146 INT2123 Positive_regulation of Gnrh1 209 0.70 24.2 68.97 100.00
147 INT24209 Negative_regulation of Ifng 37 0.57 16.52 17.15 100.00
148 INT5594 Regulation of Pdyn 137 0.62 27.04 86.63 100.00
149 INT22549 Positive_regulation of Positive_regulation of Casp3 48 0.56 29.5 23.7 100.00
150 INT12569 Localization of Oprd1 94 0.81 23.81 104.56 100.00
151 INT57024 Regulation of Gene_expression of Grin1 32 0.62 9.77 32.6 100.00
152 INT23229 Positive_regulation of H2-M3 11 0.04 1.87 8.56 100.00
153 INT48929 Regulation of Ephb1 71 0.62 24.42 42.11 100.00
154 INT7506 Negative_regulation of Ltp 267 0.46 91.01 176.8 100.00
155 INT104707 Gene_expression of Em 16 0.65 3.95 22.19 100.00
156 INT78670 Positive_regulation of Gene_expression of Dbi 26 0.70 6.72 19 100.00
157 INT64164 Regulation of Prkca 34 0.62 10.44 30.99 100.00
158 INT2555 Positive_regulation of Localization of Penk 116 0.70 24.35 119.73 100.00
159 INT64442 Regulation of Mc4r 6 0.62 5.22 19.09 100.00
160 INT1782 Regulation of Gh1 125 0.62 22 55.74 100.00
161 INT105197 Negative_regulation of GTS 14 0.37 3.88 17.14 100.00
162 INT22547 Regulation of Gene_expression of Casp3 23 0.62 8.04 16.78 100.00
163 INT26719 Negative_regulation of Gene_expression of Th 38 0.58 11.87 22.78 100.00
164 INT2782 Regulation of Gene_expression of Pomc 75 0.62 15.04 38.97 100.00
165 INT4957 Negative_regulation of Grin1 87 0.59 24.51 53.21 100.00
166 INT7800 Localization of Pag1 51 0.56 33.06 53.74 100.00
167 INT54571 Positive_regulation of NFKB1 263 0.70 138.99 87.32 100.00
168 INT55878 Regulation of Gene_expression of CCL2 34 0.62 15.71 17.97 100.00
169 INT1781 Negative_regulation of Gh1 127 0.59 16.94 51.77 100.00
170 INT7884 Regulation of Localization of Oxt 102 0.62 7.95 61.71 100.00
171 INT90300 Gene_expression of Abcb1a 56 0.78 11.05 22.89 100.00
172 INT1295 Binding of Pomc 85 0.48 12.92 42.8 100.00
173 INT881 Negative_regulation of Localization of Gh1 164 0.58 15.1 75.28 100.00
174 INT5506 Positive_regulation of Gene_expression of Pomc 132 0.70 26.78 54.3 100.00
175 INT2148 Negative_regulation of Oxt 105 0.59 11.42 57 100.00
176 INT64563 Gene_expression of UGT1A1 27 0.75 3.31 13.43 100.00
177 INT29704 Regulation of Casp3 51 0.56 22.13 22.79 100.00
178 INT2910 Regulation of Abat 169 0.62 36.95 153.53 100.00
179 INT88356 Negative_regulation of Positive_regulation of Grin1 16 0.58 4.72 16.58 100.00
180 INT52106 Negative_regulation of Localization of IL8 57 0.52 22.81 20.8 100.00
181 INT12471 Regulation of Insrr 52 0.35 17.8 48.31 100.00
182 INT7886 Regulation of Localization of Avp 146 0.62 14.53 72.99 100.00
183 INT48920 Negative_regulation of Ephb1 107 0.57 43.6 51.02 100.00
184 INT29705 Regulation of Positive_regulation of Casp3 13 0.48 5.37 10.45 100.00
185 INT2122 Negative_regulation of Localization of Gnrh1 226 0.59 26.92 92.04 100.00
186 INT12763 Phosphorylation of Prkcg 167 0.82 38.91 89.63 100.00
187 INT95726 Positive_regulation of Gene_expression of Naa15 1 0.45 1.43 13.33 100.00
188 INT40777 Positive_regulation of Akt1 163 0.69 59.41 49.43 100.00
189 INT1376 Binding of Trh 121 0.48 20 69.86 100.00
190 INT1530 Regulation of Gh 382 0.61 115.96 112.47 100.00
191 INT48222 Positive_regulation of Localization of IL8 123 0.59 78.04 37.2 100.00
192 INT873 Gene_expression of Gh1 130 0.76 26.15 46.75 100.00
193 INT58774 Negative_regulation of G2e3 8 0.38 0.22 7.75 100.00
194 INT1353 Negative_regulation of Localization of Acot1 153 0.53 15.05 75.17 100.00
195 INT6926 Regulation of Pag1 72 0.39 55.79 65.09 100.00
196 INT66381 Regulation of Prkaca 40 0.62 13.38 27.96 100.00
197 INT81626 Positive_regulation of Positive_regulation of Casp3 34 0.69 16.75 12.18 100.00
198 INT19 Regulation of Gnrhr 131 0.62 36.4 55.66 100.00
199 INT918 Positive_regulation of Localization of PRL 90 0.70 23.97 40.3 100.00
200 INT78697 Negative_regulation of Gene_expression of Casp3 33 0.57 11.22 16.16 100.00
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