P:Nav1.3

From wiki-pain
Jump to: navigation, search

pChart

Pain Term
Category Molecule
Synonyms None
Pain Specific Yes
Documents 72
Hot Single Events 160
Hot Interactions 9

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Nav1.3. They are ordered first by their pain relevance and then by number of times they were reported for Nav1.3. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT128778 Binding of Mcam and Nav1 1 0.03 0.51 2.28 100.00
2 INT128777 Binding of Cntn1 and Nav1 1 0.48 0.51 2.28 100.00
3 INT112642 Positive_regulation of Kcnma1 Positive_regulation of Nav1 1 0.02 0 0.89 100.00
4 INT119744 Binding of BHLHE22 and NAV1 1 0.29 0.49 1.09 100.00
5 INT120834 Binding of CNTN1 and SCN3A 1 0.01 0.41 0.49 100.00
6 INT119747 NAV1 Regulation of Gene_expression of BHLHE22 1 0.31 0.26 0.53 94.32
7 INT119745 NEUROD1 Regulation of Gene_expression of BHLHE22 1 0.11 0.26 0.53 93.60
8 INT119746 OR51B4 Regulation of Gene_expression of BHLHE22 1 0.08 0.26 0.52 93.04
9 INT309953 Binding of Atrn and Nav1 1 0.00 0.23 0.53 80.64
10 INT128776 Cntn1 Positive_regulation of Gene_expression of Pde6b 1 0.02 0.55 1.26 43.52
11 INT283028 Nav1 Regulation of Ca2 1 0.08 0 0.24 16.88
12 INT283027 Pirt Regulation of Ca2 1 0.00 0 0.24 16.88
13 INT211694 Binding of Cntnap1 and Nav1 1 0.04 0 3.14 5.00
14 INT317184 BMS1 Regulation of Gene_expression of NAV1 1 0.03 1.94 1.62 5.00
15 INT231391 Binding of Lpar1 and Rbm39 1 0.00 1.04 1.04 5.00
16 INT231392 Enpp2 Positive_regulation of Gene_expression of Lpar1 2 0.38 2.19 0.93 5.00
17 INT231390 Pla2g4a Regulation of Pla2g2a 1 0.08 0.92 0.77 5.00
18 INT231388 Pla2g4a Regulation of Pla2g6 1 0.08 0.92 0.77 5.00
19 INT309954 Binding of Pkp2 and Nav1 1 0.29 0.29 0.13 5.00
20 INT312841 Pou3f1 Regulation of Gene_expression of Plp1 1 0.24 0.16 0.09 5.00
21 INT312839 Egr2 Regulation of Gene_expression of Mbp 1 0.32 0.16 0.09 5.00
22 INT312843 Egr2 Regulation of Gene_expression of Plp1 1 0.31 0.16 0.09 5.00
23 INT312840 Egr2 Regulation of Gene_expression of Mag 1 0.31 0.16 0.09 5.00
24 INT312844 Pou3f1 Regulation of Gene_expression of Pmp22 1 0.27 0.16 0.09 5.00
25 INT312842 Pou3f1 Regulation of Gene_expression of Mag 1 0.24 0.16 0.09 5.00
26 INT312846 Egr2 Regulation of Gene_expression of Pmp22 1 0.35 0.16 0.09 5.00
27 INT312845 Pou3f1 Regulation of Gene_expression of Mbp 1 0.25 0.16 0.09 5.00
28 INT239980 Ts3 Regulation of Nav1 1 0.12 0 0.09 5.00
29 INT309955 Binding of Pkp2 and Dsp 1 0.12 0.1 0 5.00
30 INT309975 Binding of Pygm and Pkp2 1 0.01 0.4 0 5.00
31 INT309956 Binding of Dsc1 and Dsp 1 0.01 0.1 0 5.00
32 INT309976 Binding of Pygm and Dsp 1 0.00 0.1 0 5.00
33 INT309977 Pygm Positive_regulation of Localization of Pkp2 1 0.01 0.19 0 5.00
34 INT309957 Binding of Dsg1b and Dsp 1 0.01 0.1 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Nav1.3. They are ordered first by their pain relevance and then by number of times they were reported in Nav1.3. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT97367 Gene_expression of Nav1 243 0.78 132.97 286.66 100.00
2 INT46460 Gene_expression of NAV1 288 0.78 135.51 305.75 100.00
3 INT94450 Gene_expression of Nav1 359 0.78 131.85 275.46 100.00
4 INT100965 Positive_regulation of Nav1 85 0.70 37.74 75.35 100.00
5 INT115909 Positive_regulation of Gene_expression of Nav1 25 0.70 16.58 27.63 100.00
6 INT117674 Regulation of Gene_expression of Nav1 16 0.62 11.5 22.01 100.00
7 INT97366 Regulation of Nav1 38 0.62 23.63 38.17 100.00
8 INT117675 Transcription of Nav1 46 0.72 30.23 44.01 100.00
9 INT97368 Negative_regulation of Nav1 62 0.59 41.56 60.27 100.00
10 INT102429 Negative_regulation of Gene_expression of Nav1 19 0.59 20.09 28.09 100.00
11 INT111052 Positive_regulation of Gene_expression of Nav1 44 0.70 18.98 35.28 100.00
12 INT103262 Localization of Nav1 53 0.81 19.23 34.44 100.00
13 INT116321 Regulation of Nav1 38 0.62 26.62 37.97 100.00
14 INT129303 Positive_regulation of NAV1 54 0.70 36.92 57.45 100.00
15 INT111051 Negative_regulation of Nav1 64 0.59 25.51 47.27 100.00
16 INT145971 Localization of Nav1 20 0.81 10.3 18.11 100.00
17 INT136268 Localization of NAV1 22 0.75 2.84 26.23 100.00
18 INT137043 Transcription of NAV1 16 0.72 6.98 12.12 100.00
19 INT131413 Positive_regulation of Gene_expression of NAV1 35 0.70 17.5 36.83 100.00
20 INT123419 Binding of NAV1 37 0.48 7.09 26.43 100.00
21 INT113384 Regulation of Gene_expression of Nav1 20 0.62 8.57 16.15 100.00
22 INT112207 Binding of Nav1 27 0.47 7.1 15.43 100.00
23 INT111050 Negative_regulation of Gene_expression of Nav1 23 0.58 5.97 17.06 100.00
24 INT116226 Regulation of NAV1 20 0.51 14.32 25.61 100.00
25 INT167435 Positive_regulation of Transcription of NAV1 3 0.70 4.56 5.86 100.00
26 INT103261 Positive_regulation of Nav1 68 0.70 24.25 39.27 100.00
27 INT114507 Negative_regulation of Gene_expression of NAV1 17 0.43 7.24 15.93 100.00
28 INT112640 Positive_regulation of Negative_regulation of Nav1 3 0.50 1.26 2.98 100.00
29 INT153194 Positive_regulation of Positive_regulation of Nav1 5 0.50 3.44 4.24 100.00
30 INT76660 Gene_expression of Trpv1 691 0.78 329.46 386.42 100.00
31 INT74486 Positive_regulation of SCN1A 4 0.67 1 2.2 100.00
32 INT143450 Negative_regulation of Scn5a 3 0.43 2.71 0.88 100.00
33 INT57549 Gene_expression of GNPTAB 49 0.65 57.5 9.05 100.00
34 INT170025 Gene_expression of Fig4 588 0.67 183.27 113.32 100.00
35 INT151387 Gene_expression of Cav3 14 0.78 4 5.31 100.00
36 INT98068 Gene_expression of SCN2A 19 0.75 14.42 3.31 100.00
37 INT99105 Gene_expression of Scn3a 5 0.72 1.82 2.81 100.00
38 INT163962 Regulation of Transcription of Nav1 2 0.35 3.25 2.63 100.00
39 INT104663 Positive_regulation of SCN9A 3 0.60 0.42 2.54 100.00
40 INT13021 Positive_regulation of SCN4A 7 0.49 1.61 2.42 100.00
41 INT169659 Positive_regulation of Gene_expression of Cav3 5 0.70 1.44 2.33 100.00
42 INT153599 Gene_expression of SCN1A 8 0.75 7.01 1.47 100.00
43 INT143451 Negative_regulation of Gene_expression of Scn5a 2 0.43 4.63 1.34 100.00
44 INT278550 Positive_regulation of SCN8A 1 0.48 0 1.31 100.00
45 INT278539 Gene_expression of SCN3A 1 0.74 0 0.98 100.00
46 INT152876 Negative_regulation of Cav2 1 0.34 0.28 0.87 100.00
47 INT77610 Gene_expression of Cacna1h 6 0.65 0.47 0.8 100.00
48 INT278540 Binding of SCN7A 1 0.36 0 0.7 100.00
49 INT148659 Positive_regulation of Scn3a 1 0.06 0.64 0.67 100.00
50 INT129486 Regulation of Gene_expression of Scn3a 1 0.05 0.99 0.61 100.00
51 INT296813 Positive_regulation of Gene_expression of Cacna1h 1 0.06 0.19 0.17 100.00
52 INT151878 Gene_expression of CAV2 18 0.66 9.26 2.17 99.96
53 INT152326 Regulation of Gene_expression of CAV2 2 0.36 0.44 0.74 99.96
54 INT148661 Positive_regulation of LAMB1 2 0.05 0.64 0.67 99.90
55 INT97369 Regulation of Gene_expression of NEUROD1 1 0.26 0.25 1.12 99.84
56 INT101008 Gene_expression of Scn5a 5 0.75 26.93 6.06 99.80
57 INT5757 Gene_expression of SCN4A 6 0.75 1.73 2.73 99.78
58 INT17028 Positive_regulation of Scn7a 35 0.41 9.83 7.44 99.68
59 INT122071 Positive_regulation of Scn7a 1 0.07 0.97 1.6 99.58
60 INT85395 Gene_expression of Scn11a 62 0.78 17.97 26.89 99.56
61 INT129360 Positive_regulation of Gene_expression of Scn11a 2 0.10 0.49 1.01 99.56
62 INT14831 Negative_regulation of TNC 18 0.50 8.71 4.61 99.40
63 INT13409 Gene_expression of NEUROD1 52 0.75 14.17 12.23 99.36
64 INT278541 Positive_regulation of SCN3A 1 0.48 0 1.29 99.36
65 INT6782 Gene_expression of SCN5A 156 0.78 33.13 17.88 99.30
66 INT9556 Negative_regulation of NAV1 47 0.59 28.49 49.33 99.16
67 INT120647 Gene_expression of SCN8A 2 0.74 0.1 1.6 98.82
68 INT48240 Binding of Ngf 46 0.46 23.51 24.42 98.72
69 INT113490 Gene_expression of SCN9A 22 0.77 5.45 12.27 98.34
70 INT64076 Positive_regulation of Kcnma1 47 0.40 11.52 24.19 98.24
71 INT91888 Positive_regulation of Slc7a8 1 0.01 0 1.32 98.24
72 INT89834 Positive_regulation of SCN2A 8 0.49 1.89 2.77 98.16
73 INT141841 Negative_regulation of Transcription of Nav1 3 0.43 3.15 4.38 98.08
74 INT113376 Transcription of Nav1 7 0.69 0.93 6.36 97.88
75 INT78749 Gene_expression of SCN10A 25 0.75 9.23 16.5 97.86
76 INT85214 Gene_expression of SCN11A 24 0.78 4.05 12.5 97.36
77 INT129742 Regulation of Positive_regulation of Rtn4 2 0.05 2.51 2.33 96.80
78 INT278548 Localization of SCN7A 1 0.72 0 0.95 96.72
79 INT6117 Gene_expression of Gmcl1 4 0.49 2.39 2.33 96.52
80 INT278545 Gene_expression of SCN7A 1 0.75 0.12 6.24 96.40
81 INT56239 Positive_regulation of Rtn4 20 0.26 14.05 18.8 96.20
82 INT72252 Gene_expression of Kcnma1 63 0.64 20.47 29.56 96.04
83 INT12124 Gene_expression of MAPK1 141 0.75 82.4 25.58 95.96
84 INT71785 Gene_expression of MAPK3 22 0.75 11.35 8.21 95.96
85 INT38859 Gene_expression of SGSM3 14 0.75 12.98 4.09 95.96
86 INT113385 Negative_regulation of Transcription of Nav1 2 0.43 0.73 2.74 95.88
87 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 95.82
88 INT20632 Gene_expression of TNC 72 0.78 30.43 13.16 95.00
89 INT283029 Gene_expression of Mybpc3 1 0.01 0 1.2 94.64
90 INT145515 Positive_regulation of Localization of Trpv1 23 0.50 10.12 12.08 94.48
91 INT231378 Positive_regulation of Localization of Mtcp1 1 0.03 1.08 1.27 94.48
92 INT96622 Localization of Trpv1 110 0.81 59.82 63.25 94.16
93 INT46833 Positive_regulation of SGSM3 56 0.67 24.49 30.31 94.16
94 INT231372 Localization of Mtcp1 1 0.04 1.07 1.27 94.16
95 INT278546 Transcription of GNPTAB 3 0.03 2.19 1.1 94.00
96 INT97200 Transcription of BHLHE22 3 0.52 0.59 1.01 94.00
97 INT278543 Transcription of BHLHE23 1 0.13 0.23 0.43 94.00
98 INT278536 Transcription of OR51B4 1 0.02 0.24 0.43 94.00
99 INT71789 Positive_regulation of MAPK1 396 0.70 234.44 89.27 93.60
100 INT71787 Positive_regulation of MAPK3 37 0.67 17.5 17.88 93.60
101 INT112639 Regulation of LOC682801 4 0.34 0.72 2.58 93.44
102 INT91927 Transcription of LOC682801 6 0.07 1.47 3.93 93.44
103 INT112638 Regulation of Kcnab3 2 0.04 0.25 1.7 93.04
104 INT87753 Transcription of Kcnab3 8 0.55 1.7 4.85 93.04
105 INT3589 Positive_regulation of SCN5A 101 0.57 46.01 21.73 92.96
106 INT86646 Positive_regulation of SCN10A 71 0.69 50.61 13.24 92.96
107 INT236490 Positive_regulation of SCN11A 2 0.48 0.91 2.37 92.96
108 INT83528 Localization of Scn11a 6 0.75 1.51 1.4 92.48
109 INT76487 Localization of Cacna1h 3 0.48 0.98 0.77 92.48
110 INT296811 Gene_expression of Gja4 1 0.24 0.19 0.19 92.48
111 INT239978 Gene_expression of Ts3 1 0.64 0 0.95 91.40
112 INT105154 Regulation of Gene_expression of BHLHE22 2 0.41 0.33 0.83 91.20
113 INT135639 Gene_expression of Ina 3 0.76 9.58 2.89 90.08
114 INT27133 Gene_expression of Nfkbiz 5 0.60 0.74 1.5 90.08
115 INT143448 Gene_expression of Hrasls5 1 0.47 0.08 0.56 90.08
116 INT74983 Transcription of NA 9 0.41 1.71 2.79 89.60
117 INT5430 Gene_expression of Scn8a 37 0.75 4.58 14.82 89.56
118 INT26054 Regulation of Gene_expression of Scn8a 7 0.08 2.86 4.49 89.56
119 INT63025 Gene_expression of BHLHE22 10 0.75 3.79 3.3 89.44
120 INT296805 Positive_regulation of Kcnq1 1 0.49 0.2 0.12 88.40
121 INT5923 Negative_regulation of Rtn4 50 0.36 24.19 27.2 88.36
122 INT67130 Negative_regulation of Localization of Il1b 7 0.57 1.36 6.42 88.24
123 INT66751 Negative_regulation of Localization of Tnf 48 0.59 26 19.36 88.24
124 INT58338 Negative_regulation of Localization of Il1a 8 0.25 3.13 5.18 88.24
125 INT14031 Gene_expression of Npy 107 0.78 36.48 35.4 88.16
126 INT21646 Positive_regulation of Npy 40 0.70 31.31 13.57 88.16
127 INT21794 Positive_regulation of Gene_expression of Npy 20 0.70 8.44 9.3 88.16
128 INT75546 Transcription of Rtn4 1 0.06 2.87 5.03 88.08
129 INT1599 Positive_regulation of ADCY1 146 0.67 30.05 64.9 87.36
130 INT11429 Gene_expression of ADCY1 26 0.74 5.89 11.93 87.36
131 INT251445 Gene_expression of Kcne1 2 0.73 0.61 0.3 87.04
132 INT296817 Positive_regulation of Gene_expression of Kcne1 1 0.66 0.39 0.19 87.04
133 INT10166 Localization of Tnf 237 0.81 153.95 88.64 86.80
134 INT9347 Localization of Il1b 58 0.81 26.13 31.53 86.80
135 INT5966 Localization of Il1a 50 0.78 22.91 26.54 86.80
136 INT13051 Regulation of Kcnma1 12 0.12 2.09 5.06 85.20
137 INT163963 Negative_regulation of Transcription of Rtn4 1 0.03 0.45 1.06 84.24
138 INT171820 Localization of Fig4 144 0.65 27.38 20.88 83.64
139 INT10706 Regulation of Il6 150 0.62 93.23 62.34 83.00
140 INT74286 Regulation of Il10 42 0.44 28.06 19.44 83.00
141 INT112967 Regulation of Mcpt1 15 0.54 13.03 8.58 83.00
142 INT62452 Regulation of Il2 14 0.61 12.11 7.64 83.00
143 INT58484 Regulation of Il4 12 0.45 8.67 6.09 83.00
144 INT52133 Regulation of Localization of Il6 7 0.61 5.35 4.37 83.00
145 INT157048 Regulation of Localization of Mcpt1 3 0.18 0.31 2.73 83.00
146 INT157049 Regulation of Localization of Il4 2 0.25 1.46 2.33 83.00
147 INT127740 Regulation of Localization of Il10 3 0.60 0.65 2.18 83.00
148 INT157050 Regulation of Localization of Il2 1 0.06 0 1.67 83.00
149 INT139350 Binding of SCN1B 2 0.35 1 2.43 82.76
150 INT278537 Binding of SCN2B 1 0.29 0.13 2.29 82.76
151 INT278549 Binding of SCN3B 1 0.34 0.13 2.29 82.76
152 INT278542 Binding of SCN4B 1 0.35 0.13 2.29 82.76
153 INT152877 Negative_regulation of Ndufa10 1 0.02 0.4 0.87 82.72
154 INT19511 Localization of Il6 212 0.81 118.17 67.67 82.40
155 INT72564 Localization of Il10 41 0.78 28.62 17.6 82.40
156 INT110767 Localization of Mcpt1 43 0.68 24.3 16.74 82.40
157 INT50040 Localization of Il4 15 0.67 8.26 7.69 82.40
158 INT12066 Localization of Il2 16 0.75 3.06 5.7 82.40
159 INT53070 Regulation of Rtn4 15 0.22 9.35 13.77 81.64
160 INT117422 Gene_expression of Pirt 13 0.33 2.17 5.23 81.04
161 INT22491 Binding of Atrn 23 0.30 4.51 7.79 79.84
162 INT125624 Gene_expression of Atp8a2 12 0.15 3.91 4.85 79.48
163 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 78.28
164 INT6097 Negative_regulation of NEUROD1 30 0.57 9.71 6.24 77.92
165 INT119748 Negative_regulation of BHLHE22 1 0.13 0.27 0.48 77.92
166 INT10169 Positive_regulation of Localization of Tnf 44 0.70 27.71 16.75 77.88
167 INT48954 Positive_regulation of Localization of Il1b 13 0.53 8.16 6.44 77.88
168 INT5968 Positive_regulation of Localization of Il1a 4 0.65 1.36 2.42 77.88
169 INT6623 Gene_expression of NA 231 0.78 45.78 59.36 77.24
170 INT296810 Negative_regulation of Binding of Kcne1 1 0.40 0.23 0.1 76.92
171 INT98156 Binding of Kcne1 2 0.37 0.32 0.1 76.92
172 INT296808 Negative_regulation of Kcne1 1 0.40 0.23 0.1 76.56
173 INT120836 Positive_regulation of CNTN1 1 0.48 1.42 1.4 75.00
174 INT77601 Gene_expression of OR51B4 15 0.58 2.07 6.19 75.00
175 INT136651 Binding of Calm2 30 0.42 1.09 3.11 75.00
176 INT120843 Gene_expression of CNTN1 7 0.54 4.27 1.06 75.00
177 INT51898 Binding of PECAM1 26 0.36 18.87 4.22 75.00
178 INT57645 Gene_expression of GSTK1 54 0.62 21.05 4.2 75.00
179 INT148658 Negative_regulation of Csnk1a1 2 0.08 0.99 0.75 75.00
180 INT148660 Negative_regulation of Ppp3ca 1 0.02 0.59 0.67 75.00
181 INT120839 Binding of CNTN1 2 0.34 0.75 0.52 75.00
182 INT120838 Positive_regulation of Gene_expression of CNTN1 1 0.35 0.45 0.48 75.00
183 INT120844 Negative_regulation of CNTN1 2 0.26 0.52 0.47 75.00
184 INT120841 Positive_regulation of Localization of CNTN1 1 0.35 0.52 0.46 75.00
185 INT120842 Localization of CNTN1 1 0.52 0.52 0.46 75.00
186 INT137836 Negative_regulation of Binding of Calm2 2 0.51 0 0.23 75.00
187 INT33170 Binding of Chrm1 11 0.48 1.58 2.1 73.84
188 INT296815 Regulation of Gene_expression of Kcne1 1 0.43 0.19 0.07 73.44
189 INT73335 Gene_expression of ACTB 21 0.58 5.62 1.94 72.92
190 INT48312 Gene_expression of NTRK1 72 0.78 38.21 22.24 72.64
191 INT96492 Gene_expression of NGFR 24 0.00 12.3 4.59 72.64
192 INT111049 Negative_regulation of Positive_regulation of Nav1 5 0.43 4.39 6.25 72.08
193 INT31796 Gene_expression of Enpep 5 0.65 0.42 2.32 71.92
194 INT32786 Localization of Enpep 4 0.68 0 1.16 71.92
195 INT48008 Negative_regulation of Pde6b 9 0.15 6.12 4.11 71.68
196 INT4449 Positive_regulation of NA 179 0.55 40.26 37.82 70.16
197 INT111053 Positive_regulation of Positive_regulation of Nav1 4 0.46 2.97 3.53 69.64
198 INT117676 Positive_regulation of Transcription of Nav1 8 0.53 4.37 7.75 66.24
199 INT95787 Positive_regulation of Mapk1 568 0.70 226.51 220.94 65.76
200 INT59671 Positive_regulation of Scn8a 7 0.39 1.88 5.92 65.04
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox