P:Neuropathic pain

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pChart

Pain Term
Category Pain type
Synonyms None
Pain Specific Yes
Documents 7046
Hot Single Events 200
Hot Interactions 200

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Neuropathic pain. They are ordered first by their pain relevance and then by number of times they were reported for Neuropathic pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT155460 Tnfrsf1a Positive_regulation of Positive_regulation of Nfkb1 1 0.42 2.39 1.82 100.00
2 INT140892 Penk Negative_regulation of Mnp 1 0.13 0.55 1.75 100.00
3 INT160119 EPO Regulation of Gene_expression of NFKB1 1 0.02 0.2 0.64 100.00
4 INT249483 Binding of Ephb1 and Efnb2 1 0.02 2.35 1.66 100.00
5 INT249481 Positive_regulation of Binding of Ephb1 and Efnb2 1 0.03 1.36 1.12 100.00
6 INT114844 Lgals1 Positive_regulation of TACR1 1 0.16 0.95 0.82 100.00
7 INT146780 Positive_regulation of Fgfr1 Positive_regulation of Mapk14 1 0.34 0.95 0.77 100.00
8 INT219279 Ctss Positive_regulation of Gene_expression of Fam64a 1 0.06 1.39 0.96 99.96
9 INT219273 Fam64a Positive_regulation of Gene_expression of Ctss 1 0.06 1.39 0.96 99.96
10 INT153815 LPA Positive_regulation of Gene_expression of Gtf3a 1 0.00 0.16 0.1 99.92
11 INT155663 Positive_regulation of P2rx4 Positive_regulation of Localization of Bdnf 1 0.42 0.84 1.25 99.80
12 INT164784 Il6 Positive_regulation of Gene_expression of Cx3cr1 1 0.47 2.37 1.98 99.78
13 INT161224 Ccl2 Positive_regulation of Ccr2 1 0.52 2.09 1.88 99.68
14 INT161225 Ccl2 Positive_regulation of Ccl2 Positive_regulation of Ccr2 1 0.57 2.09 1.88 99.68
15 INT155459 Tnfrsf1a Positive_regulation of Nfkb1 1 0.42 2.45 1.63 99.60
16 INT139706 Tnf Positive_regulation of Ltp 1 0.03 2.61 4.63 99.44
17 INT332773 Positive_regulation of Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.04 0.73 1.75 99.36
18 INT161769 Cck Regulation of Cckar 1 0.27 0.53 0.92 99.36
19 INT351366 LPA Positive_regulation of Rab38 1 0.00 0.95 1.53 99.32
20 INT158282 Binding of Penk and Csf2 1 0.33 0.87 1.44 99.24
21 INT76396 Il10 Negative_regulation of Il1b 2 0.65 1.89 1.08 99.12
22 INT158283 Binding of Penk and Accn4 1 0.07 0.87 1.43 99.04
23 INT130839 Gfap Positive_regulation of S100B 1 0.51 1.9 1.56 98.96
24 INT130838 Gfap Positive_regulation of Aqp4 1 0.51 1.9 1.56 98.96
25 INT152501 Binding of Tnf and Tnfrsf1a 4 0.31 3 2.58 98.96
26 INT286798 Binding of Il6st and Cntf 1 0.10 1.34 0.97 98.76
27 INT127585 Binding of CNR2 and Ctbp1 1 0.00 0.6 0.76 98.64
28 INT127584 Binding of CNR1 and Ctbp1 1 0.00 0.6 0.75 98.64
29 INT102201 Tnf Regulation of Il1b 3 0.39 2.57 0.82 98.56
30 INT281155 Binding of ITIH4 and Ddc 1 0.09 1.27 0.37 98.56
31 INT110994 Tnf Regulation of Il6 1 0.17 0.67 0.36 98.56
32 INT150890 Binding of Esr1 and Esr2 2 0.52 2.06 1.31 98.48
33 INT139641 Positive_regulation of Jun Positive_regulation of Positive_regulation of Vip 1 0.37 0.95 0.99 98.40
34 INT139638 Positive_regulation of Jun Positive_regulation of Positive_regulation of Npy 1 0.36 1.18 0.96 98.40
35 INT291578 Negative_regulation of Pde12 Positive_regulation of Pde5a 1 0.03 1.11 1.67 98.32
36 INT209087 Crh Positive_regulation of Ceacam3 1 0.24 1.45 1.54 98.24
37 INT137092 Ntf3 Negative_regulation of Gene_expression of Gal 1 0.47 1.01 0.9 98.20
38 INT125284 FSCN1 Positive_regulation of Positive_regulation of EPHB2 1 0.04 0.4 1.14 98.16
39 INT140532 Gtf3a Positive_regulation of DYT10 1 0.12 1.83 1.34 98.16
40 INT140531 Ngf Positive_regulation of DYT10 1 0.72 1.83 1.34 98.16
41 INT134681 FSCN1 Positive_regulation of FSCN1 Positive_regulation of MAPK8 1 0.00 0.56 1.39 98.12
42 INT134679 FSCN1 Positive_regulation of MAPK8 1 0.01 0.56 1.39 98.12
43 INT107104 Positive_regulation of Binding of Bdnf and Ntrk2 1 0.42 1.86 1.34 98.08
44 INT146306 Binding of Chrna9 and Myo5c 1 0.01 0.27 0.48 98.04
45 INT72754 Adamts7 Negative_regulation of TNF 1 0.28 1.64 1.13 97.92
46 INT315284 PRKG1 Positive_regulation of Nos1 1 0.33 0.85 1.56 97.84
47 INT164150 Binding of S100a8 and Trpv1 1 0.04 0.6 0.62 97.84
48 INT126384 Binding of Bdnf and Ntrk2 Positive_regulation of Prkca 1 0.49 0.63 0.85 97.64
49 INT68514 Pnoc Positive_regulation of Oprl1 10 0.59 3.56 9.57 97.60
50 INT270218 P2rx3 Positive_regulation of Pla2g4a 1 0.34 0.63 0.85 97.48
51 INT262577 Localization of Ngf Positive_regulation of Positive_regulation of Mapk14 1 0.05 0.92 0.75 97.48
52 INT72755 Tap1 Negative_regulation of TNF 1 0.43 2.45 1.46 97.44
53 INT349658 Nos2 Regulation of Gene_expression of Nos1 1 0.63 2.86 1.84 97.40
54 INT139640 Jun Regulation of Gene_expression of Npy 1 0.21 1.98 1.75 97.32
55 INT105668 Binding of AAVS1 and BDNF 1 0.08 0.94 0.95 97.28
56 INT349657 Nos2 Regulation of Regulation of Nos1 1 0.24 0.9 0.8 97.26
57 INT149743 Ean5 Positive_regulation of Gene_expression of P2rx2 1 0.10 1.54 1.5 97.24
58 INT308174 Binding of TNF and P2rx7 1 0.02 0.84 0.56 97.24
59 INT281241 Positive_regulation of P2RX7 Negative_regulation of Gene_expression of P2rx3 1 0.03 0.79 0.71 97.16
60 INT244421 Binding of DST and Ctss 1 0.02 0.42 0.41 97.08
61 INT128044 Bdnf Positive_regulation of Ephb1 2 0.31 1.89 2.57 97.04
62 INT96811 Nfkb1 Regulation of Gene_expression of IK 1 0.00 1.06 0.87 97.00
63 INT281085 Binding of Gria2 and Nsf 2 0.26 0.4 0.94 97.00
64 INT116227 Pnoc Negative_regulation of NAV1 1 0.02 0.1 0.48 96.92
65 INT106559 Binding of Bdnf and Ntrk2 23 0.43 11.09 7.33 96.88
66 INT166134 Binding of Cxcl12 and Cxcr4 3 0.49 5.69 3.17 96.64
67 INT166135 Regulation of Binding of Cxcl12 and Cxcr4 1 0.30 0.9 0.91 96.64
68 INT82267 Lif Regulation of Gene_expression of Gal 1 0.40 2.76 0.62 96.64
69 INT275398 Binding of ITIH4 and Htatsf1 1 0.02 5.05 2.24 96.60
70 INT296484 Binding of Gria2 and GRIP1 1 0.04 4.52 4.59 96.52
71 INT275406 Binding of ITIH4 and Ccr5 1 0.09 2.88 0.97 96.52
72 INT275387 Binding of Lamp1 and Ccr5 1 0.01 1.45 0.52 96.52
73 INT275405 Binding of GOLPH3 and Ccr5 1 0.00 1.46 0.52 96.52
74 INT139230 Icam1 Negative_regulation of Cmklr1 1 0.19 1.13 1.07 96.24
75 INT139229 Calca Negative_regulation of Cmklr1 1 0.19 1.12 1.06 96.24
76 INT275409 Binding of ITIH4 and Cxcr4 1 0.09 2.87 0.97 96.04
77 INT275388 Binding of Lamp1 and Cxcr4 1 0.01 1.45 0.52 96.04
78 INT275403 Binding of Cxcr4 and GOLPH3 1 0.00 1.45 0.52 96.04
79 INT199493 Ngf Regulation of Oprd1 1 0.05 1.05 1.15 95.88
80 INT69340 Binding of Igh-6 and Ngf 2 0.06 1.04 1.06 95.80
81 INT72213 Positive_regulation of PRKCA Regulation of Gene_expression of METTL3 1 0.05 0.17 0.93 95.76
82 INT153963 Gatsl2 Regulation of Abat 1 0.02 0.97 1.03 95.72
83 INT292988 Negative_regulation of SGCG Positive_regulation of GABRB3 1 0.01 0.3 0.89 95.56
84 INT74159 Ngf Regulation of Gene_expression of Calca 2 0.60 1.66 3.22 95.48
85 INT287744 Lpar3 Positive_regulation of Positive_regulation of Lpar1 1 0.46 0.39 0.58 95.36
86 INT287753 Lpar3 Positive_regulation of Gene_expression of Lpar1 1 0.46 0.39 0.58 95.36
87 INT144450 Regulation of Nqo1 Regulation of Nos1 1 0.11 0.1 0.34 95.36
88 INT139227 Icam1 Negative_regulation of Timp1 1 0.37 1.13 1.06 95.12
89 INT139231 Calca Negative_regulation of Timp1 1 0.36 1.11 1.05 95.12
90 INT344973 Negative_regulation of Mmp23 Regulation of Negative_regulation of Mag 1 0.01 1.14 0.99 95.12
91 INT283050 Binding of Gad2 and Trpm8 1 0.23 2.02 1.93 95.04
92 INT345180 Binding of Lpar4 and Gpr87 1 0.06 0.69 0.59 95.04
93 INT345192 Binding of Gpr87 and Lpar5 1 0.07 0.69 0.59 95.04
94 INT134686 FSCN1 Positive_regulation of Gfap 1 0.00 0.71 1.89 94.92
95 INT284785 Gch1 Regulation of Bh4p 1 0.00 1.48 1.54 94.64
96 INT334351 Bdnf Regulation of Positive_regulation of Ephb1 1 0.18 1.27 1.2 94.48
97 INT132689 Tnf Regulation of Dnajc13 1 0.01 1.27 0.65 94.36
98 INT113610 Binding of Nsf and Grip2 1 0.24 0.6 0.63 94.20
99 INT113611 Binding of Pick1 and Grip2 1 0.31 0.6 0.63 94.20
100 INT95405 Trib3 Positive_regulation of Phosphorylation of Ephb1 3 0.08 1.33 1.89 94.08
101 INT261482 Pik3cb Positive_regulation of Phosphorylation of Ephb1 1 0.23 0.67 0.58 94.08
102 INT139225 Calca Negative_regulation of Icam1 1 0.44 1.13 1.06 93.88
103 INT139226 Icam1 Negative_regulation of Calca 1 0.44 1.12 1.05 93.88
104 INT281373 Tcf21 Regulation of Fig4 1 0.03 0.67 1.2 93.88
105 INT281379 Tcf21 Regulation of FSCN1 1 0.01 0.66 1.19 93.88
106 INT190775 Gene_expression of Il4 Negative_regulation of Positive_regulation of FOSL1 1 0.39 2.42 1.4 93.60
107 INT287752 Dmbx1 Positive_regulation of Positive_regulation of Lpar1 1 0.41 0.39 0.58 93.60
108 INT287749 Dmbx1 Positive_regulation of Gene_expression of Lpar1 1 0.41 0.82 1.16 93.60
109 INT292990 SGCG Positive_regulation of Gene_expression of GABRB3 1 0.01 0.29 0.87 93.52
110 INT292987 SGCG Positive_regulation of NCOR2 1 0.00 0.29 0.87 93.52
111 INT292989 SGCG Positive_regulation of GABRB3 1 0.01 0.29 0.87 93.52
112 INT144448 Nqo1 Regulation of Nos1 1 0.11 0.09 0.34 93.28
113 INT348402 LPA Positive_regulation of Gene_expression of Ptgs2 1 0.01 0.62 0.48 93.24
114 INT159962 Rock2 Regulation of Localization of Il6 1 0.09 2.7 0.88 93.08
115 INT324926 Ptpro Positive_regulation of Bdkrb2 1 0.01 2.25 1.5 92.96
116 INT281381 FSCN1 Positive_regulation of Gene_expression of Gfap 1 0.06 1.13 1.98 92.80
117 INT281382 FSCN1 Positive_regulation of Sds 1 0.02 0.84 1.33 92.80
118 INT147506 Binding of Ncam1 and Gtf3a 1 0.03 0.88 0.99 92.80
119 INT147504 Binding of Ncam1 and Gdnf 1 0.31 0.87 0.98 92.80
120 INT212301 NGF Regulation of Gene_expression of TRPV1 1 0.23 2.37 2.13 92.64
121 INT252858 C5 Negative_regulation of Positive_regulation of Trpa1 1 0.02 0.78 0.74 92.64
122 INT164782 Il6 Regulation of Gene_expression of Cx3cr1 1 0.27 0.79 0.67 92.24
123 INT116556 Olr1627 Negative_regulation of Regulation of Tnf 1 0.01 1.52 0.87 92.20
124 INT116555 Olr1627 Negative_regulation of Positive_regulation of Nfkb1 1 0.02 1.51 0.86 92.20
125 INT116559 Olr1627 Negative_regulation of Regulation of Ptgs2 1 0.01 1.52 0.86 92.20
126 INT116557 Olr1627 Negative_regulation of Localization of Nfkb1 1 0.02 1.51 0.85 92.20
127 INT91267 Gdnf Negative_regulation of Gdnf 1 0.05 0.81 0.58 92.04
128 INT164783 Positive_regulation of Mapk14 Regulation of Gene_expression of Cx3cr1 1 0.19 0.81 0.68 92.04
129 INT114319 TNF Positive_regulation of Gene_expression of Il6r 1 0.05 0.91 0.61 92.04
130 INT165183 Ifnb1 Positive_regulation of P2rx4 1 0.04 1.73 1.73 91.92
131 INT133650 Epo Negative_regulation of TNF 1 0.35 2.7 1.04 91.84
132 INT159963 Tnf Positive_regulation of Localization of Il6 1 0.12 2.32 0.71 91.76
133 INT146276 Binding of P2RX4 and P2RX7 1 0.38 0.38 0.43 91.68
134 INT287746 Anxa1 Positive_regulation of Gene_expression of Lpar1 1 0.07 1.72 2.46 91.60
135 INT155259 RUNX1 Negative_regulation of Tnf 1 0.00 1.48 0.93 91.40
136 INT274866 Mapk1 Positive_regulation of Gene_expression of TNF 1 0.06 0.35 0.33 91.24
137 INT190772 Il4 Negative_regulation of Gene_expression of Ptger2 1 0.03 1.28 1.49 91.12
138 INT190773 Il4 Negative_regulation of Gene_expression of Ptgs2 1 0.06 1.26 1.45 91.12
139 INT190774 Il4 Negative_regulation of Positive_regulation of Ptgs2 1 0.06 1.26 1.45 91.12
140 INT190130 Binding of CPOX and MRXS5 1 0.00 1.4 1.23 91.12
141 INT100559 Binding of Grin1 and LOC502940 1 0.13 0.61 0.8 91.12
142 INT120834 Binding of CNTN1 and SCN3A 1 0.01 0.41 0.49 90.76
143 INT351367 LPA Regulation of Trpv1 1 0.01 0.83 0.69 90.56
144 INT160304 Npy Regulation of Gene_expression of Fos 3 0.67 1.43 1.68 90.52
145 INT252857 Binding of F2rl1 and Trpa1 1 0.22 0.84 0.63 90.44
146 INT252859 Binding of Ngf and Trpa1 1 0.19 0.84 0.62 90.44
147 INT247925 Slc12a2 Regulation of Cl 1 0.01 1.44 1.23 90.40
148 INT247926 Slc12a5 Regulation of Cl 1 0.01 1.43 1.23 90.40
149 INT130128 Binding of Ocln and Tjp1 2 0.38 0.98 0.29 90.36
150 INT315769 GRIN1 Negative_regulation of Plbd1 1 0.00 0.57 0.87 90.32
151 INT293200 Positive_regulation of Grin1 Positive_regulation of Phosphorylation of Grin2b 1 0.24 0.4 1.39 90.28
152 INT247924 Slc12a5 Regulation of Gene_expression of Slc12a2 1 0.25 1.43 1.23 90.24
153 INT171823 Nrgn Positive_regulation of Prkcg 1 0.18 0.53 0.36 90.24
154 INT308175 Negative_regulation of Mapk14 Negative_regulation of Localization of TNF 1 0.03 0.89 0.61 90.00
155 INT139642 Positive_regulation of Jun Regulation of Gene_expression of Npy 1 0.21 1.07 0.97 90.00
156 INT147507 Binding of Ret and Gtf3a 1 0.03 0.81 0.92 89.84
157 INT147505 Binding of Ret and Gdnf 1 0.27 0.81 0.92 89.84
158 INT139156 Binding of Gria1 and Gria2 1 0.23 0.64 1.72 89.84
159 INT215598 Positive_regulation of P2rx7 Positive_regulation of Localization of TNF 1 0.22 1.44 0.85 89.80
160 INT291579 Pde12 Regulation of Binding of Pde5a 1 0.02 0.41 0.6 89.60
161 INT155457 Tnfrsf1a Positive_regulation of Mapk14 1 0.20 1.17 0.67 89.52
162 INT155462 Tnfrsf1a Positive_regulation of Nfkb1 Regulation of Gene_expression of Il6 1 0.20 1.17 0.67 89.52
163 INT155458 Tnfrsf1a Regulation of Gene_expression of Il6 1 0.22 1.11 0.63 89.52
164 INT296950 Tacr1 Negative_regulation of Gene_expression of Cck 1 0.30 0.94 1.11 89.32
165 INT139429 LPA Positive_regulation of Negative_regulation of MBP 1 0.00 0.78 0.56 89.12
166 INT155761 Binding of Nos1 and Tjp1 1 0.13 1.01 0.82 88.96
167 INT155760 Binding of Nos1 and Dlg4 1 0.13 1.01 0.82 88.96
168 INT144451 Napa Positive_regulation of Gene_expression of Nqo1 1 0.07 0.18 0.8 88.92
169 INT195541 Lct Positive_regulation of Gene_expression of Grm2 1 0.02 0.4 1.27 88.80
170 INT131256 Positive_regulation of Nfkb1 Positive_regulation of Gene_expression of Nfkbia 1 0.38 0.94 1.31 88.64
171 INT219280 Mapk14 Positive_regulation of Pla2g2a 1 0.33 0.46 0.61 88.32
172 INT219282 Mapk14 Positive_regulation of Pla2g1b 1 0.18 0.46 0.61 88.32
173 INT219277 Mapkapk2 Positive_regulation of Pla2g1b 1 0.03 0.46 0.61 88.16
174 INT219278 Mapkapk2 Positive_regulation of Pla2g2a 1 0.05 0.46 0.61 88.16
175 INT296460 Binding of Gria2 and Myo18a 1 0.01 1.49 1.06 87.92
176 INT330379 Gene_expression of IL10 Negative_regulation of Positive_regulation of MAPK14 1 0.00 1.95 1.18 87.92
177 INT144449 Plscr1 Positive_regulation of Gene_expression of Nqo1 1 0.15 0.18 0.8 87.88
178 INT195552 Binding of Rela and Ep300 1 0.03 0.2 0.45 87.76
179 INT195554 Binding of Nfkb1 and Ep300 1 0.08 0.2 0.45 87.76
180 INT274895 Positive_regulation of Cbr2 Negative_regulation of Gene_expression of TNF 1 0.06 1.21 0.99 87.60
181 INT351365 LPA Positive_regulation of Localization of Il6 1 0.00 1.79 0.54 87.52
182 INT308176 TNF Regulation of Tnfrsf1a 1 0.05 1.19 0.75 87.44
183 INT215596 Bdnf Positive_regulation of Negative_regulation of Slc12a5 1 0.14 0.76 0.86 87.36
184 INT167757 Binding of Enpp2 and Dmbx1 1 0.22 0.33 0.13 87.32
185 INT196576 Trib3 Positive_regulation of Phosphorylation of Mapk9 1 0.02 0.5 0.85 87.28
186 INT149597 Lif Regulation of Regulation of Gal 1 0.30 0.69 0.73 87.16
187 INT339318 Ngf Positive_regulation of Pik3cg 1 0.02 0.69 0.87 86.96
188 INT196578 Ephb1 Positive_regulation of Phosphorylation of Mapk9 1 0.13 0.5 0.85 86.96
189 INT285659 Binding of Faah and Mgll 1 0.15 0.99 1.11 86.88
190 INT134522 Nrg1 Regulation of Gene_expression of Mpz 1 0.60 0.29 0.25 86.88
191 INT108647 Binding of Grin2a and Camk1d 1 0.33 0.78 0.9 86.84
192 INT296463 Binding of Gria1 and Pick1 1 0.16 0.32 0.59 86.84
193 INT308172 Rvm Positive_regulation of Phosphorylation of GRIN1 1 0.50 0.68 1.14 86.80
194 INT324927 Syt17 Positive_regulation of Bdkrb1 1 0.04 4.29 2.96 86.76
195 INT219274 Binding of Cx3cr1 and Cx3cl1 1 0.17 1.08 0.74 86.68
196 INT261483 Binding of Ephb1 and Trpv1 1 0.39 1.37 1.37 86.48
197 INT281153 Binding of ITIH4 and Cd4 1 0.10 0.91 0.37 86.36
198 INT139705 Negative_regulation of Tnf Positive_regulation of Ltp 1 0.03 1.19 2.3 86.32
199 INT231392 Enpp2 Positive_regulation of Gene_expression of Lpar1 2 0.38 2.19 0.93 86.32
200 INT292075 FSCN1 Positive_regulation of Gene_expression of Csnk1a1 1 0.03 0.57 0.52 86.16

Single Events

The table below shows the top 200 pain related interactions that have been reported for Neuropathic pain. They are ordered first by their pain relevance and then by number of times they were reported in Neuropathic pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT16260 Gene_expression of Bdnf 671 0.78 283.44 339.1 100.00
2 INT65054 Positive_regulation of Nfkb1 285 0.70 149.33 126.73 100.00
3 INT9131 Positive_regulation of Prkcg 431 0.70 130.8 302.41 100.00
4 INT104523 Positive_regulation of FSCN1 14 0.12 10.09 20.08 100.00
5 INT77855 Gene_expression of Pain1 55 0.75 67.42 54.1 100.00
6 INT84170 Positive_regulation of Gene_expression of Ccl2 58 0.69 48.79 32.43 100.00
7 INT166119 Negative_regulation of Gene_expression of Lpar1 17 0.51 13.86 8.7 100.00
8 INT24569 Negative_regulation of Pain1 26 0.41 21.82 21.08 100.00
9 INT66200 Gene_expression of Gfap 215 0.78 88.04 28.25 100.00
10 INT47680 Regulation of Gene_expression of Bdnf 92 0.62 41.61 53.24 100.00
11 INT97368 Negative_regulation of Nav1 62 0.59 41.56 60.27 100.00
12 INT5380 Positive_regulation of Gene_expression of Fos 243 0.70 105.65 131.05 100.00
13 INT11012 Positive_regulation of Creb1 258 0.70 84.4 132 100.00
14 INT104000 Phosphorylation of Grin2b 73 0.82 48.34 93.48 100.00
15 INT195203 Binding of Tenc1 14 0.32 13.97 8.28 100.00
16 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71 100.00
17 INT82882 Localization of Ccl2 61 0.80 41.96 28 100.00
18 INT101474 Positive_regulation of Gene_expression of Gfap 61 0.70 38.3 10.35 100.00
19 INT26973 Gene_expression of Tenc1 59 0.66 27.19 12 100.00
20 INT161221 Positive_regulation of Positive_regulation of Ccr2 3 0.50 4.55 3.98 100.00
21 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99 100.00
22 INT72884 Positive_regulation of Tenc1 13 0.42 14.01 7.67 100.00
23 INT26972 Negative_regulation of Tenc1 57 0.57 56.71 16.87 100.00
24 INT9299 Positive_regulation of Positive_regulation of Npr1 32 0.53 6.65 16.72 100.00
25 INT178828 Regulation of Pain1 12 0.14 16.1 15.64 100.00
26 INT51602 Gene_expression of Grm5 59 0.75 17.29 26.99 100.00
27 INT81537 Regulation of Gene_expression of Nfkb1 10 0.57 7.09 7.48 100.00
28 INT65057 Regulation of Nfkb1 28 0.47 16.48 11.62 100.00
29 INT125384 Positive_regulation of Pain1 23 0.49 17.1 14.83 100.00
30 INT44979 Positive_regulation of Pnp 11 0.59 5.61 2.41 100.00
31 INT3550 Negative_regulation of GLA 52 0.59 33.93 5.26 100.00
32 INT8732 Positive_regulation of Gene_expression of Oprm1 76 0.70 22.59 58.83 100.00
33 INT215593 Binding of P2ry6 1 0.31 2.53 2.09 100.00
34 INT183249 Binding of P2ry12 12 0.47 7.4 3.3 100.00
35 INT18981 Gene_expression of ABAT 78 0.68 38.35 61.36 100.00
36 INT145097 Negative_regulation of Pain1 16 0.22 19.11 16.82 100.00
37 INT4877 Gene_expression of MME 184 0.78 122.82 24.78 100.00
38 INT211853 Phosphorylation of Tenc1 2 0.61 2.53 1.59 100.00
39 INT58079 Localization of Tenc1 13 0.68 5.9 4.75 100.00
40 INT99587 Positive_regulation of Gene_expression of Oprk1 15 0.57 5.26 12.39 100.00
41 INT87890 Regulation of Gene_expression of Pnoc 8 0.44 2.45 7.66 100.00
42 INT102056 Protein_catabolism of Tenc1 14 0.84 6.29 2.14 100.00
43 INT122117 Negative_regulation of Gene_expression of Grin2b 20 0.59 11.3 12.55 100.00
44 INT166920 Binding of Neu1 2 0.21 2.67 0.63 100.00
45 INT42971 Binding of Hivep3 14 0.42 3.92 8.99 100.00
46 INT86769 Positive_regulation of Gene_expression of Rbm39 11 0.25 5.6 3.8 100.00
47 INT202374 Negative_regulation of Transcription of Aqp4 2 0.37 1.34 0.69 100.00
48 INT327797 Negative_regulation of Transcription of Gfap 1 0.16 1.27 0.69 100.00
49 INT12424 Binding of Npy 48 0.48 8.23 24.26 100.00
50 INT327799 Negative_regulation of Transcription of Cnp 1 0.05 1.25 0.68 100.00
51 INT327800 Transcription of Cnp 2 0.09 1.32 0.85 100.00
52 INT122300 Negative_regulation of Positive_regulation of Nqo1 2 0.59 1.07 1.84 100.00
53 INT140891 Regulation of Mnp 1 0.13 0.49 1.62 100.00
54 INT51690 Negative_regulation of Mnp 3 0.26 2.36 2.95 100.00
55 INT62426 Gene_expression of Mc1r 127 0.78 42.99 48.01 100.00
56 INT71868 Regulation of Tenc1 9 0.52 10.73 4.09 100.00
57 INT7717 Positive_regulation of Adra2a 62 0.70 17.68 27.32 100.00
58 INT222241 Binding of Ccr2 5 0.42 4.09 3.71 100.00
59 INT15462 Negative_regulation of Il1a 4 0.59 4.68 4.17 100.00
60 INT244384 Binding of Slc12a5 2 0.46 2.47 1.71 100.00
61 INT62523 Positive_regulation of Phosphorylation of Oprm1 11 0.53 0.75 12.51 100.00
62 INT145773 Positive_regulation of Localization of C5 1 0.49 1.15 1.06 100.00
63 INT60434 Negative_regulation of Positive_regulation of Tnf 20 0.46 10.01 10.64 100.00
64 INT87139 Negative_regulation of Positive_regulation of Il6 18 0.59 10.65 7.76 100.00
65 INT160786 Regulation of Tada1 1 0.16 0.69 1.04 100.00
66 INT247970 Regulation of CLTC 8 0.28 5.37 1.06 100.00
67 INT190093 Regulation of Gene_expression of Hivep3 1 0.49 1.06 1.32 100.00
68 INT351277 Positive_regulation of Gene_expression of FMOD 1 0.10 5.79 2.25 100.00
69 INT79758 Regulation of Gene_expression of Gal 6 0.54 5.45 3.22 100.00
70 INT95739 Negative_regulation of Phosphorylation of Mapk8 11 0.42 6.77 2.61 100.00
71 INT56016 Positive_regulation of Pzp 5 0.47 3.11 3.22 100.00
72 INT4880 Regulation of MME 17 0.61 7.78 8.2 100.00
73 INT107522 Regulation of Grm5 9 0.44 6.42 11.46 100.00
74 INT156296 Regulation of Trpv4 20 0.45 7.84 4.86 100.00
75 INT244392 Binding of Slc12a2 3 0.35 2.05 1.68 100.00
76 INT210527 Positive_regulation of Gene_expression of Tenc1 14 0.38 6.37 2.45 100.00
77 INT147397 Negative_regulation of Binding of Grin2b 1 0.16 0.87 0.63 100.00
78 INT104493 Negative_regulation of Mapk8 56 0.53 27.76 16.86 100.00
79 INT183207 Negative_regulation of USE1 14 0.18 10.97 4 100.00
80 INT136690 Regulation of Negative_regulation of Tnf 5 0.45 3.58 0.78 100.00
81 INT250978 Binding of FMOD 4 0.16 12.32 8.75 100.00
82 INT316709 Positive_regulation of Gene_expression of Pain1 3 0.49 2.39 1.5 100.00
83 INT130610 Positive_regulation of Positive_regulation of Vipr2 1 0.10 0.26 0.61 100.00
84 INT43906 Regulation of Tlr4 71 0.53 35.18 15.49 100.00
85 INT77877 Regulation of P9Ehs1 13 0.38 3.31 10.04 100.00
86 INT114524 Binding of GRIN2B 3 0.36 0.44 0.74 100.00
87 INT63932 Positive_regulation of Ephb1 537 0.70 259.67 296.14 99.98
88 INT64110 Positive_regulation of Gene_expression of Nos1 68 0.70 58.11 51.64 99.98
89 INT64048 Positive_regulation of Positive_regulation of Tnf 32 0.70 21.24 13.74 99.98
90 INT22939 Gene_expression of Csf2 164 0.78 85.1 32.22 99.98
91 INT114023 Positive_regulation of Transcription of Nos1 7 0.60 5.35 8.06 99.98
92 INT119380 Positive_regulation of LPAR1 2 0.02 1.23 0.91 99.98
93 INT68279 Positive_regulation of Gene_expression of Csf2 30 0.67 16.31 6.88 99.98
94 INT103967 Negative_regulation of Gene_expression of BAK1 8 0.42 7.02 1.54 99.98
95 INT5379 Gene_expression of Fos 656 0.78 255.5 292.54 99.96
96 INT16253 Positive_regulation of Gene_expression of Bdnf 196 0.70 92.67 113.01 99.96
97 INT7114 Positive_regulation of Ltp 1192 0.62 290.76 755.77 99.96
98 INT49519 Gene_expression of P2rx7 84 0.76 36.88 34.69 99.96
99 INT101578 Regulation of Cnr2 26 0.62 16.7 19.12 99.96
100 INT84495 Positive_regulation of Positive_regulation of Ephb1 85 0.70 46.12 54.11 99.96
101 INT61873 Gene_expression of Arc 128 0.78 128.25 52.24 99.96
102 INT125411 Negative_regulation of Phosphorylation of Mapk14 31 0.57 18.55 19.98 99.96
103 INT107575 Positive_regulation of Gene_expression of Atf3 25 0.69 27.37 14.55 99.96
104 INT70437 Negative_regulation of Mdk 115 0.57 41.03 35.72 99.96
105 INT129685 Negative_regulation of FSCN1 7 0.05 3.44 5.69 99.96
106 INT8528 Negative_regulation of Gene_expression of Fos 100 0.59 41.15 55.6 99.96
107 INT9298 Positive_regulation of Gtpbp4 64 0.69 12.29 41.97 99.96
108 INT228873 Positive_regulation of Negative_regulation of Dmbx1 1 0.48 1.09 0.72 99.96
109 INT295467 Negative_regulation of Gene_expression of Tlr4 11 0.58 7.94 6.83 99.96
110 INT131744 Transcription of Trpa1 9 0.68 7.67 6.47 99.96
111 INT121171 Negative_regulation of Gene_expression of Ngfr 6 0.58 3.46 3.89 99.96
112 INT17349 Negative_regulation of Akr1b1 41 0.59 27.03 10.65 99.96
113 INT130611 Positive_regulation of Vipr2 2 0.18 0.26 0.75 99.96
114 INT94952 Positive_regulation of Mapk14 305 0.70 197.83 186.61 99.92
115 INT133211 Gene_expression of Runx1 169 0.77 83.4 76.16 99.92
116 INT64202 Positive_regulation of Trpv1 643 0.70 249.66 397.42 99.92
117 INT60126 Regulation of Trpv1 186 0.62 85.53 133.4 99.92
118 INT88046 Gene_expression of Ccr2 38 0.76 33.76 28.07 99.92
119 INT79093 Positive_regulation of Nos1 101 0.70 46.89 59.61 99.92
120 INT5895 Gene_expression of Oprm1 525 0.78 120.67 407.29 99.92
121 INT99336 Negative_regulation of FOLH1 30 0.57 8.83 11.53 99.92
122 INT151120 Negative_regulation of Tlr4 18 0.59 21.09 14.46 99.92
123 INT84171 Negative_regulation of Gene_expression of Ccl2 30 0.58 26.37 18.28 99.92
124 INT3300 Positive_regulation of Gene_expression of Calca 179 0.70 77.76 144.2 99.92
125 INT168991 Negative_regulation of P2rx4 9 0.43 12.77 9.39 99.92
126 INT108427 Gene_expression of Il15 9 0.76 5.13 4.63 99.92
127 INT6486 Positive_regulation of Tnf 168 0.70 123.47 66.05 99.92
128 INT88047 Positive_regulation of Gene_expression of Ccr2 15 0.60 10.5 8.63 99.92
129 INT93281 Negative_regulation of Folh1 12 0.50 5.55 10.63 99.92
130 INT76469 Positive_regulation of Gene_expression of Prkca 18 0.46 7.9 13.36 99.92
131 INT186230 Positive_regulation of Timd4 2 0.01 2.54 2.93 99.92
132 INT68882 Binding of P2rx7 16 0.23 4.33 6.17 99.92
133 INT6487 Positive_regulation of Positive_regulation of Tnf 21 0.56 16.06 5.64 99.92
134 INT82610 Positive_regulation of SRC 53 0.67 26.89 7.27 99.92
135 INT80918 Regulation of Transcription of Oprk1 1 0.62 1.2 1.89 99.92
136 INT167122 Protein_catabolism of ABCA1 3 0.02 0.27 0.37 99.92
137 INT167120 Protein_catabolism of Cx3cl1 1 0.07 0.19 0.15 99.92
138 INT86521 Gene_expression of Lpar1 167 0.78 154.61 80.35 99.90
139 INT130479 Phosphorylation of Grin2b 28 0.77 34.82 34.97 99.90
140 INT130475 Positive_regulation of Phosphorylation of Grin2b 8 0.47 11.52 10.96 99.90
141 INT66753 Negative_regulation of Positive_regulation of Tnf 45 0.59 35.28 22.33 99.90
142 INT58226 Negative_regulation of Gene_expression of Il1b 24 0.57 18.09 12.68 99.90
143 INT101683 Positive_regulation of Ots1 3 0.38 2.67 2.31 99.90
144 INT166880 Negative_regulation of Gene_expression of Ccl3 1 0.57 0.81 1.01 99.90
145 INT89516 Negative_regulation of Grm8 7 0.41 4.01 3.82 99.90
146 INT35450 Negative_regulation of Htr2a 7 0.47 3.46 3.33 99.90
147 INT168637 Negative_regulation of Cx3cr1 6 0.58 11.67 2.41 99.90
148 INT58061 Gene_expression of Trpv1 1117 0.78 451.54 637.59 99.88
149 INT110023 Negative_regulation of Mapk14 127 0.59 84.27 45.42 99.88
150 INT16259 Positive_regulation of Bdnf 336 0.70 183.48 209.82 99.88
151 INT110020 Gene_expression of Mapk14 142 0.77 72.33 30.08 99.88
152 INT165490 Regulation of Lpar1 8 0.45 15.31 5.05 99.88
153 INT78797 Regulation of Tmem132a 8 0.45 3.61 12.73 99.88
154 INT119089 Regulation of Phosphorylation of Grin1 17 0.61 3.1 12.82 99.88
155 INT58062 Negative_regulation of Gene_expression of Trpv1 66 0.59 22.34 38.02 99.88
156 INT104342 Regulation of FSCN1 4 0.15 3.18 4.84 99.88
157 INT332775 Regulation of Phosphorylation of FSCN1 1 0.02 0.19 0.95 99.88
158 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 99.86
159 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 99.86
160 INT48895 Gene_expression of Il10 333 0.78 221.2 138.52 99.86
161 INT163066 Transcription of Gfap 12 0.69 4.47 3.21 99.86
162 INT13354 Transcription of TNF 108 0.72 85.81 42.32 99.86
163 INT50933 Transcription of Il6 38 0.72 24.31 11.58 99.86
164 INT202378 Transcription of Aqp4 5 0.65 1.7 1.02 99.86
165 INT48892 Transcription of Il10 31 0.71 27.26 16.77 99.86
166 INT74826 Gene_expression of Slc1a2 131 0.78 61.83 100.84 99.84
167 INT51163 Gene_expression of Gal 119 0.78 67.48 49.23 99.84
168 INT74827 Positive_regulation of Gene_expression of Slc1a2 52 0.70 26.54 50.63 99.84
169 INT86789 Gene_expression of P2rx4 46 0.77 30.66 25.68 99.84
170 INT12001 Regulation of Ngf 97 0.62 54.64 76.25 99.84
171 INT1665 Positive_regulation of Pag1 270 0.68 186.63 229.87 99.84
172 INT5839 Positive_regulation of Transcription of Gfap 10 0.49 11.61 6.74 99.84
173 INT130835 Positive_regulation of Transcription of Aqp4 3 0.68 4.5 3.28 99.84
174 INT29971 Gene_expression of Oprk1 126 0.78 35.32 93.97 99.84
175 INT23787 Positive_regulation of P2rx7 36 0.68 23.54 19.45 99.84
176 INT10706 Regulation of Il6 150 0.62 93.23 62.34 99.84
177 INT49170 Negative_regulation of Nos1 116 0.59 60.66 58.87 99.84
178 INT87686 Positive_regulation of Gene_expression of Trpv1 101 0.70 72.41 69.15 99.84
179 INT1425 Gene_expression of Rbm39 143 0.58 51.32 65.44 99.84
180 INT155348 Positive_regulation of Aqp4 14 0.63 9.92 5.53 99.84
181 INT77434 Positive_regulation of Gene_expression of Nos2 151 0.69 96.76 38.94 99.84
182 INT49172 Regulation of Nos1 43 0.52 27.53 23.66 99.84
183 INT40777 Positive_regulation of Akt1 163 0.69 59.41 49.43 99.84
184 INT292062 Negative_regulation of Csnk1a1 1 0.44 7.57 6.52 99.84
185 INT6052 Gene_expression of Ptn 12 0.78 8.4 6.5 99.84
186 INT88365 Regulation of Faah 18 0.45 6.63 12.54 99.84
187 INT95646 Negative_regulation of Faah 63 0.59 25.61 36.78 99.84
188 INT66531 Gene_expression of Pnoc 88 0.78 22.9 65.11 99.84
189 INT98110 Regulation of Gene_expression of Slc1a2 16 0.62 11.76 17.31 99.84
190 INT120446 Positive_regulation of Cnr2 32 0.70 16.3 18.91 99.84
191 INT520 Binding of Comt 24 0.48 8.98 12.21 99.84
192 INT121242 Positive_regulation of Gene_expression of Nos3 37 0.69 31.96 12.71 99.84
193 INT127962 Positive_regulation of GRHL3 3 0.32 2.67 3.69 99.84
194 INT120966 Positive_regulation of Pik3cb 34 0.68 15.15 16.59 99.84
195 INT26534 Regulation of Akt1 34 0.61 14.47 11.86 99.84
196 INT50058 Negative_regulation of Cpox 907 0.58 426.28 428.29 99.84
197 INT99539 Positive_regulation of Slc1a2 25 0.67 5.46 23.38 99.84
198 INT87451 Positive_regulation of Mapk3 34 0.67 12.82 10.38 99.84
199 INT15613 Negative_regulation of Ptgs2 160 0.59 71.08 65.08 99.84
200 INT46833 Positive_regulation of SGSM3 56 0.67 24.49 30.31 99.84
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