P:Norepinephrine uptake inhibitor

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pChart

Pain Term
Category Drug class
Synonyms Norepinephrine Uptake Inhibitors
Pain Specific No
Documents 30
Hot Single Events 33
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Norepinephrine uptake inhibitor. They are ordered first by their pain relevance and then by number of times they were reported for Norepinephrine uptake inhibitor. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT127437 deltaFosB Negative_regulation of Vta1 1 0.01 0.09 1.06 95.56

Single Events

The table below shows the top 200 pain related interactions that have been reported for Norepinephrine uptake inhibitor. They are ordered first by their pain relevance and then by number of times they were reported in Norepinephrine uptake inhibitor. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT6824 Regulation of Gene_expression of Pdyn 114 0.62 9.48 66.73 100.00
2 INT5596 Negative_regulation of Gene_expression of Pdyn 41 0.59 5.34 24.36 99.98
3 INT5597 Gene_expression of Pdyn 433 0.78 62.97 235.47 99.70
4 INT49850 Negative_regulation of PDE4A 105 0.58 76.91 26.59 99.66
5 INT27170 Gene_expression of Maoa 13 0.67 3.88 7.5 99.66
6 INT13415 Positive_regulation of Hpse 58 0.70 24.9 25.53 98.48
7 INT31774 Positive_regulation of Vta1 67 0.44 14.52 71.79 98.44
8 INT53384 Positive_regulation of FosB 41 0.69 8.43 28.91 98.00
9 INT69621 Positive_regulation of Positive_regulation of Hpse 7 0.42 4.1 2.85 96.04
10 INT5598 Negative_regulation of Pdyn 95 0.59 14.4 55.43 95.60
11 INT70572 Gene_expression of Fst 33 0.78 5.22 8.24 95.00
12 INT33094 Regulation of Localization of Ca2 28 0.38 8.65 9.96 94.80
13 INT53385 Positive_regulation of Gene_expression of FosB 26 0.70 9.18 26.33 94.12
14 INT6228 Localization of Htr1a 14 0.78 0.46 6.2 93.28
15 INT50587 Regulation of Localization of Htr1a 1 0.44 0 0.52 93.28
16 INT21527 Gene_expression of FosB 47 0.78 11.2 34.39 93.20
17 INT1437 Negative_regulation of Pomc 132 0.59 35.22 60.97 93.08
18 INT5593 Positive_regulation of Gene_expression of Pdyn 114 0.70 29.1 74.46 92.76
19 INT4822 Localization of Ca2 417 0.80 99.57 96.45 92.08
20 INT6762 Binding of Srms 56 0.31 6.62 30.27 91.24
21 INT1316 Positive_regulation of Acot1 129 0.60 18.86 56.13 91.24
22 INT940 Negative_regulation of Ptgs1 219 0.59 104.34 95.97 90.12
23 INT112986 Positive_regulation of S100b 19 0.70 17.61 6.86 88.80
24 INT20060 Protein_catabolism of Acot1 6 0.56 0.22 2.45 88.48
25 INT22721 Regulation of Protein_catabolism of Acot1 2 0.23 0.17 0.53 88.48
26 INT605 Regulation of Acot1 61 0.62 10.7 26.34 88.08
27 INT24420 Transcription of Pomc 13 0.69 3.32 4.54 86.76
28 INT112988 Positive_regulation of Transcription of S100b 2 0.47 1.62 1.36 85.56
29 INT5595 Positive_regulation of Pdyn 223 0.70 48.37 130.14 85.12
30 INT10120 Negative_regulation of Positive_regulation of Pdyn 14 0.58 6.05 10.19 85.12
31 INT112987 Transcription of S100b 2 0.53 1.61 1.35 84.76
32 INT84965 Gene_expression of MAOA 15 0.75 6.9 6.06 80.08
33 INT244283 Negative_regulation of Gene_expression of MAOA 2 0.27 1.7 2.5 80.08
34 INT3188 Regulation of Localization of Acot1 84 0.59 8.94 38.56 79.96
35 INT29322 Negative_regulation of Srms 5 0.37 0.31 3.37 78.92
36 INT2640 Gene_expression of Pomc 424 0.78 120.72 155.37 78.80
37 INT1353 Negative_regulation of Localization of Acot1 153 0.53 15.05 75.17 78.08
38 INT1352 Localization of Acot1 728 0.80 73.01 296.01 77.36
39 INT40034 Localization of Maoa 7 0.80 2.17 3.69 76.64
40 INT2416 Negative_regulation of MAOA 92 0.59 42.24 36.5 75.36
41 INT5594 Regulation of Pdyn 137 0.62 27.04 86.63 75.00
42 INT1023 Negative_regulation of Pxk 13 0.59 0.76 2.7 73.68
43 INT25965 Gene_expression of Pxk 9 0.78 2 0.78 73.68
44 INT59095 Regulation of Regulation of Srms 1 0.23 0 0.41 73.44
45 INT29853 Regulation of Srms 3 0.53 0.09 1.31 72.96
46 INT50585 Positive_regulation of Line 1 0.40 0 1.02 71.68
47 INT195085 Gene_expression of S100b 12 0.56 12.26 2.33 71.56
48 INT1438 Localization of Pomc 360 0.81 101.26 116.47 71.36
49 INT15347 Positive_regulation of Localization of Pomc 81 0.70 28.1 31.01 71.36
50 INT439 Localization of Gnrh1 976 0.81 100.96 363.25 70.88
51 INT4289 Positive_regulation of Localization of Gnrh1 202 0.70 12.3 84.01 70.88
52 INT50586 Regulation of Line 1 0.23 0 1.03 67.68
53 INT6176 Positive_regulation of Htr1a 117 0.67 28.23 66.17 57.68
54 INT108433 Negative_regulation of Mat1a 16 0.57 14.15 2.82 57.20
55 INT54052 Gene_expression of App 33 0.78 25.08 14.7 47.48
56 INT39846 Gene_expression of Olr1746 12 0.75 0.61 3.22 25.00
57 INT127436 Positive_regulation of Tfap2d 1 0.08 0 0.33 25.00
58 INT158 Localization of Prl 2431 0.81 378.96 952.2 5.00
59 INT155 Positive_regulation of Prl 1233 0.70 317.93 457.82 5.00
60 INT16260 Gene_expression of Bdnf 671 0.78 283.44 339.1 5.00
61 INT16259 Positive_regulation of Bdnf 336 0.70 183.48 209.82 5.00
62 INT16253 Positive_regulation of Gene_expression of Bdnf 196 0.70 92.67 113.01 5.00
63 INT49651 Gene_expression of Creb1 276 0.78 114.77 111.96 5.00
64 INT1169 Negative_regulation of Bche 322 0.59 149.22 61.27 5.00
65 INT8713 Regulation of Tac1 56 0.60 25.29 45.94 5.00
66 INT88617 Positive_regulation of Gene_expression of Creb1 90 0.69 51.69 44.29 5.00
67 INT96557 Binding of Bdnf 46 0.47 21.74 24.26 5.00
68 INT9231 Binding of Htr3a 27 0.47 7.29 13.04 5.00
69 INT56031 Positive_regulation of App 25 0.69 13.46 7.37 5.00
70 INT50105 Localization of CTSB 29 0.78 10.98 5.21 5.00
71 INT78116 Positive_regulation of Gene_expression of App 12 0.70 10.78 4.52 5.00
72 INT52402 Negative_regulation of Htr2c 7 0.42 1.46 4.21 5.00
73 INT6063 Positive_regulation of Bche 17 0.66 6.07 3.08 5.00
74 INT54055 Regulation of Gene_expression of App 7 0.62 4.04 2.93 5.00
75 INT229111 Localization of SLC6A3 5 0.68 1.12 2.48 5.00
76 INT81154 Gene_expression of HCRT 10 0.75 5.32 2.22 5.00
77 INT39008 Localization of App 13 0.77 9.07 2.05 5.00
78 INT50106 Positive_regulation of Localization of CTSB 9 0.33 3.15 1.69 5.00
79 INT148883 Gene_expression of HCRTR1 8 0.36 24.82 1.35 5.00
80 INT244284 Binding of SLC18A2 1 0.23 1.87 1.34 5.00
81 INT103488 Positive_regulation of Localization of App 5 0.50 3.05 1.28 5.00
82 INT99281 Negative_regulation of HCRT 3 0.57 2.26 0.71 5.00
83 INT264605 Negative_regulation of Binding of Htr3a 1 0.01 1.12 0.64 5.00
84 INT148884 Negative_regulation of HCRTR1 7 0.23 7.23 0.53 5.00
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