P:Nucleus accumbens

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Pain Term
Category Anatomy
Synonyms Accumbens Nucleus, Nucleus Accumbens Septi
Pain Specific No
Documents 2258
Hot Single Events 200
Hot Interactions 200

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Nucleus accumbens. They are ordered first by their pain relevance and then by number of times they were reported for Nucleus accumbens. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT164362 Binding of NLRP1 and VTA1 1 0.15 2.37 4.67 100.00
2 INT164365 Positive_regulation of Binding of NLRP1 and VTA1 1 0.14 0.6 1.21 100.00
3 INT137657 Gorasp2 Regulation of Binding of Casp3 1 0.09 0 1.52 100.00
4 INT261461 Positive_regulation of Akr1d1 Regulation of Sftpd 1 0.01 0 0.86 100.00
5 INT221783 Nlrp1a Negative_regulation of Camk4 1 0.08 1.39 0.55 100.00
6 INT189999 Binding of Vta1 and Cfp 2 0.08 1.25 1.97 100.00
7 INT265707 Binding of NA and Cfp 1 0.01 0 0.62 100.00
8 INT114281 Binding of Oprd1 and Nacc1 1 0.03 0 0.74 100.00
9 INT216668 Positive_regulation of NLRP1 Regulation of Vta1 1 0.00 0 0.73 100.00
10 INT221784 Nlrp1a Positive_regulation of Gene_expression of Crem 1 0.05 0.61 0.22 100.00
11 INT136172 NPY Negative_regulation of Positive_regulation of Drd1a 1 0.21 0 0.91 100.00
12 INT164363 Regulation of Binding of NLRP1 and VTA1 1 0.14 0.45 0.86 100.00
13 INT211747 Negative_regulation of Binding of Oprm1 and Mors1 1 0.09 0 1.86 100.00
14 INT211746 Binding of Oprm1 and Mors1 1 0.08 0 1.78 100.00
15 INT96545 Nacc1 Regulation of Gene_expression of Penk 1 0.05 0 0.41 100.00
16 INT29996 Binding of Oprm1 and Penk 2 0.36 0.4 1.85 100.00
17 INT126801 Regulation of Binding of Oprm1 and Penk 1 0.34 0.4 1.25 100.00
18 INT49231 TAC1 Negative_regulation of Penk 1 0.00 0 1.3 99.86
19 INT156623 Umod Regulation of Phosphorylation of Ephb1 1 0.05 0.33 2.27 99.84
20 INT116250 Vta1 Positive_regulation of Casp3 1 0.01 0 0.82 99.78
21 INT116251 Vta1 Positive_regulation of Localization of Pdyn 1 0.01 0 0.74 99.60
22 INT162224 Grin1 Positive_regulation of Gene_expression of Gria1 1 0.27 0.07 0.66 99.60
23 INT261458 Akr1d1 Regulation of Sftpd 1 0.01 0 0.82 99.56
24 INT156622 Umod Regulation of Phosphorylation of Creb1 1 0.05 0.33 2.27 99.52
25 INT166388 Binding of Gnb2l1 and Mapk1 1 0.49 0.49 1.21 99.48
26 INT166387 Binding of Gnb2l1 and Mdk 1 0.30 0.24 0.61 99.48
27 INT166385 Binding of Araf and Gnb2l1 1 0.23 0.24 0.6 99.48
28 INT327702 Binding of Comt and Drd2 1 0.28 0.27 0.74 99.44
29 INT179443 Vta1 Positive_regulation of Gpr156 1 0.20 0 1.99 99.44
30 INT179445 Vta1 Positive_regulation of Gabrd 1 0.09 0 1.98 99.44
31 INT228852 Th Positive_regulation of Vta1 1 0.04 0 0.53 99.32
32 INT228851 Th Positive_regulation of Mtf2 1 0.02 0 0.52 99.32
33 INT75069 Penk Regulation of Gene_expression of Pkhd1l1 1 0.09 0 1.85 99.24
34 INT55087 Binding of Gad1 and Penk 1 0.08 0 0.32 99.24
35 INT162223 Grin1 Positive_regulation of Localization of Gria2 1 0.23 0.07 0.66 99.20
36 INT210985 Positive_regulation of Calb1 Positive_regulation of Cysltr1 1 0.00 0.81 0.69 99.20
37 INT69938 Cck Positive_regulation of Localization of Abat 2 0.29 0 3.78 99.16
38 INT7292 Binding of Drd1a and Penk 1 0.14 0 0.9 99.16
39 INT300608 Arc Regulation of Dnm2 1 0.15 0.27 0.37 99.12
40 INT60584 Positive_regulation of Htr3a Positive_regulation of Localization of Cck 1 0.52 0.43 1.09 99.12
41 INT327707 Binding of Comt and Drd1a 1 0.18 0.27 0.74 99.08
42 INT12453 Sigmar1 Regulation of Gene_expression of Penk 2 0.35 0 0.43 99.00
43 INT300610 Rorb Regulation of Dnm2 1 0.01 0.27 0.37 98.96
44 INT7023 Negative_regulation of Drd1a Positive_regulation of Npr1 2 0.05 0.1 1.81 98.94
45 INT210981 Calb1 Positive_regulation of Cysltr1 1 0.00 0.81 0.69 98.94
46 INT72640 Ntsr1 Regulation of Nts 1 0.13 0.07 0.3 98.88
47 INT69937 Cck Positive_regulation of Abat 2 0.31 0 2.88 98.84
48 INT327712 Binding of Comt and Rbm39 1 0.00 0.27 0.74 98.84
49 INT7022 Drd1a Positive_regulation of Npr1 6 0.05 0.26 4.32 98.78
50 INT33314 Binding of Ap1m1 and Ap1m2 1 0.07 0.97 5.42 98.76
51 INT2653 Slc3a1 Regulation of Penk 3 0.04 0.37 1.96 98.72
52 INT51203 Binding of OPRK1 and OPRM1 2 0.29 0.3 1.36 98.64
53 INT51200 Binding of OPRM1 and PENK 2 0.17 0.23 1.31 98.64
54 INT51630 Binding of ACHE and OPRM1 1 0.11 0 0.33 98.64
55 INT106753 Pes1 Negative_regulation of Gene_expression of Casp3 2 0.12 0 2.19 98.60
56 INT215789 Fig4 Positive_regulation of Localization of P2rx7 1 0.03 0.53 0.29 98.60
57 INT153516 PLG Positive_regulation of Pas5a 1 0.57 0.05 0.83 98.56
58 INT160183 Fbxo23 Regulation of Gabrg1 1 0.02 0.07 0.55 98.52
59 INT23755 Mptp1 Regulation of PDYN 1 0.01 2.27 1.98 98.50
60 INT7025 Positive_regulation of Drd1a Positive_regulation of Npr1 1 0.04 0.08 1.01 98.40
61 INT113080 Drd1a Positive_regulation of Phosphorylation of Creb1 2 0.27 0.43 3.88 98.36
62 INT136250 Phosphorylation of Tff3 Regulation of Creb1 1 0.02 0.18 1.24 98.36
63 INT110650 Pla2g3 Regulation of Grip2 1 0.01 0 0.68 98.36
64 INT115413 Binding of Penk and Oxtr 1 0.00 0 0.25 98.20
65 INT210983 Calb1 Positive_regulation of Cnr1 1 0.01 0.81 0.68 98.18
66 INT329278 Vta1 Positive_regulation of Gene_expression of Fos 1 0.22 0 0.82 98.16
67 INT37882 Penk Positive_regulation of LOC100366054 1 0.08 0.35 1.93 98.04
68 INT103359 Binding of Mapk3 and Mink1 1 0.09 0.17 0.22 98.00
69 INT103356 Positive_regulation of Binding of Mapk1 and Mapk3 1 0.41 0.17 0.22 98.00
70 INT103357 Binding of Mapk1 and Mapk3 1 0.32 0.17 0.22 98.00
71 INT51629 Binding of DRD3 and OPRK1 1 0.15 0 0.33 97.88
72 INT261447 Sftpd Positive_regulation of Akr1d1 1 0.01 0 0.77 97.56
73 INT136257 Tff3 Regulation of SGCG 1 0.00 0.18 1.24 97.50
74 INT136256 Creb1 Regulation of SGCG 1 0.26 0.18 1.23 97.50
75 INT327708 Binding of Drd1a and Drd2 1 0.12 0.12 0.37 97.40
76 INT136255 Tff3 Regulation of GRIA1 1 0.00 0.18 1.24 97.34
77 INT136258 Creb1 Regulation of GRIA1 1 0.26 0.18 1.23 97.34
78 INT122728 Pes1 Positive_regulation of Transcription of Penk 1 0.07 0 0.81 97.08
79 INT244025 Prkaca Regulation of Phosphorylation of Gabrg1 1 0.08 0.18 0.72 97.04
80 INT244055 Prkaca Regulation of Gabrg1 1 0.08 0 0.58 97.04
81 INT141907 F2r Regulation of Plat 1 0.46 0 1.59 96.96
82 INT129953 Oprd1 Regulation of Cspg5 1 0.17 0.15 1.74 96.96
83 INT151339 Positive_regulation of Binding of Drd2 and P9Ehs1 1 0.11 0.22 0.76 96.88
84 INT235882 Creb1 Positive_regulation of Positive_regulation of Bdnf 1 0.11 0.17 0.47 96.72
85 INT235878 Creb1 Positive_regulation of Gene_expression of Bcl2 1 0.05 0.17 0.38 96.72
86 INT13344 Binding of Npy and Adarb1 2 0.02 0.41 0.73 96.68
87 INT106750 Pes1 Negative_regulation of Positive_regulation of Casp3 3 0.23 0 2.35 96.64
88 INT136249 Drd1a Positive_regulation of Phosphorylation of Tff3 1 0.01 0.18 1.23 96.52
89 INT7024 Regulation of Drd1a Positive_regulation of Npr1 1 0.04 0.07 1.13 96.36
90 INT122727 Pes1 Positive_regulation of Penk 1 0.07 0 0.81 96.36
91 INT244028 Positive_regulation of Binding of Cacnb3 and Tfap2a 1 0.01 0.24 0.49 96.28
92 INT244037 Positive_regulation of Binding of Prkaca and Tfap2a 1 0.01 0.24 0.49 96.28
93 INT244021 Positive_regulation of Binding of Cacnb3 and Prkaca 1 0.02 0.24 0.49 96.28
94 INT243999 Positive_regulation of Binding of Prkaca and Dnm1 1 0.14 0.24 0.49 96.28
95 INT244000 Positive_regulation of Binding of Tfap2a and Dnm1 1 0.04 0.24 0.49 96.28
96 INT51628 Binding of ACHE and DRD3 1 0.15 0 0.33 96.24
97 INT51631 Binding of DRD3 and PENK 1 0.08 0 0.33 96.24
98 INT63803 RGD1560349 Positive_regulation of Penk 1 0.04 0 1 96.04
99 INT103358 Binding of Mapk1 and Mink1 1 0.07 0.17 0.22 96.04
100 INT119334 Binding of Calcrl and Positive_regulation of Gpr182 1 0.19 0.13 0.3 95.84
101 INT119333 Binding of Ramp2 and Positive_regulation of Gpr182 1 0.18 0.13 0.3 95.84
102 INT119332 Binding of Ramp3 and Positive_regulation of Gpr182 1 0.18 0.13 0.3 95.84
103 INT106751 Pes1 Negative_regulation of Casp3 2 0.23 0 1.54 95.84
104 INT124767 Creb1 Regulation of Oprm1 1 0.45 0 1.26 95.84
105 INT243998 Binding of Prkaca and Dnm1 1 0.11 0.24 0.49 95.76
106 INT244036 Binding of Cacnb3 and Prkaca 1 0.01 0.24 0.49 95.76
107 INT244035 Binding of Prkaca and Tfap2a 1 0.01 0.24 0.49 95.76
108 INT151340 Binding of Drd2 and P9Ehs1 1 0.09 0.22 0.75 95.68
109 INT142413 Oprm1 Positive_regulation of Gdnf 1 0.19 0.29 1.09 95.68
110 INT41152 Binding of Penk and Slc3a1 3 0.12 0.11 2.91 95.24
111 INT261457 Sftpd Positive_regulation of Vta1 1 0.10 0 0.63 95.24
112 INT182839 Camk4 Positive_regulation of Creb1 3 0.49 1.81 0.79 95.20
113 INT243997 Binding of Tfap2a and Dnm1 1 0.03 0.24 0.49 95.20
114 INT245347 Binding of Penk and Vta1 1 0.05 0.14 1.53 95.08
115 INT339000 Binding of LMOD1 and GSX1 1 0.01 0 0.3 94.96
116 INT52955 Binding of Slc6a3 and Pdpn 1 0.17 1.11 1.22 94.88
117 INT191331 AMPH Positive_regulation of Gene_expression of Vta1 1 0.07 0 0.66 94.72
118 INT191330 AMPH Positive_regulation of Vta1 1 0.07 0 0.66 94.72
119 INT191332 AMPH Positive_regulation of Mapk1 1 0.76 0 0.66 94.72
120 INT164364 Binding of DRD2 and SUGT1 2 0.06 0.33 0.77 94.44
121 INT148257 NR4A2 Regulation of Gene_expression of SLC6A3 1 0.60 0.4 0.59 94.44
122 INT166386 Mapk1 Regulation of Gene_expression of Gnb2l1 1 0.46 0.25 0.7 94.32
123 INT33815 Vta1 Negative_regulation of Penk 1 0.25 0 1.54 94.28
124 INT244060 Binding of Cacnb3 and Tfap2a 1 0.00 0.24 0.49 94.24
125 INT301166 LRP2 Regulation of TRD@ 1 0.12 1.93 1.21 94.20
126 INT160184 Fbxo23 Positive_regulation of Gabrg1 1 0.04 0.06 0.52 94.12
127 INT339002 Binding of OPRD1 and GSX1 1 0.00 0 0.3 93.88
128 INT29119 Nts Regulation of Oprd1 1 0.18 0.79 0.31 93.32
129 INT29118 Trh Regulation of Oprd1 1 0.24 0.79 0.31 93.32
130 INT339001 GSX1 Positive_regulation of ADCY1 1 0.01 0 0.29 92.72
131 INT286702 Positive_regulation of Mapk1 Positive_regulation of Positive_regulation of Rps6ka5 1 0.37 0.18 0.29 92.12
132 INT286705 Positive_regulation of Mapk1 Positive_regulation of Phosphorylation of Rps6ka5 1 0.37 0.18 0.29 92.12
133 INT286699 Positive_regulation of Mapk1 Positive_regulation of Phosphorylation of Creb1 1 0.22 0.18 0.28 92.12
134 INT286708 Negative_regulation of Mapk1 Negative_regulation of Casp3 1 0.12 0 0.31 91.88
135 INT337112 Negative_regulation of Nr1d2-rs2 Positive_regulation of Mapk1 1 0.00 0.14 0.33 91.76
136 INT337110 Negative_regulation of Nr1d2-rs2 Positive_regulation of Phosphorylation of Hist1h3f 1 0.00 0.14 0.33 91.76
137 INT321475 Slc6a2 Positive_regulation of Ubqln1 1 0.00 0.38 1.19 91.76
138 INT286703 Mapk1 Positive_regulation of Phosphorylation of Hist1h3f 1 0.22 0.18 0.29 91.72
139 INT286706 Mapk1 Positive_regulation of Phosphorylation of Rps6ka5 1 0.37 0.18 0.29 91.72
140 INT286704 Mapk1 Positive_regulation of Phosphorylation of Creb1 1 0.32 0.18 0.28 91.72
141 INT286709 Mapk1 Positive_regulation of Rps6ka5 Positive_regulation of Rps6ka5 1 0.36 0.18 0.28 91.72
142 INT286707 Mapk1 Positive_regulation of Positive_regulation of Rps6ka5 1 0.37 0.18 0.28 91.72
143 INT182837 Binding of Creb1 and Crebbp 1 0.12 0.57 0.32 91.28
144 INT112607 DNAJC15 Negative_regulation of Positive_regulation of Casp3 1 0.03 0.14 1.12 91.20
145 INT112608 DNAJC15 Regulation of Gene_expression of Fos 1 0.02 0.14 1.12 91.20
146 INT286701 Rps6ka5 Positive_regulation of Phosphorylation of Creb1 1 0.20 0.18 0.28 90.84
147 INT321046 Anpep Regulation of Negative_regulation of Hps4 1 0.02 0.25 0.43 90.40
148 INT321479 Ubqln1 Regulation of Cfp 1 0.00 0.37 0.67 90.28
149 INT309708 Palm Regulation of Positive_regulation of Penk 1 0.19 1.25 0.91 90.24
150 INT95059 Binding of Oprm1 and Slc18a3 1 0.04 0 0.52 90.20
151 INT151338 Binding of Dio1 and P9Ehs1 1 0.09 0.16 0.52 90.04
152 INT7291 Akr1d1 Regulation of Regulation of Penk 1 0.01 0 0.48 89.96
153 INT321047 Anpep Regulation of Negative_regulation of Ptpn6 1 0.01 0.25 0.43 89.84
154 INT134294 Binding of Pdyn and Penk 1 0.23 0 2.69 89.80
155 INT140312 Oprm1 Regulation of Gene_expression of Penk 1 0.07 0.26 0.77 89.52
156 INT73679 Nkx1-1 Positive_regulation of Tacr3 1 0.22 0.26 1.12 89.12
157 INT261394 Nsdhl Negative_regulation of nt 1 0.01 1.69 0.24 89.12
158 INT327700 Binding of Comt and 4930579C15Rik 1 0.08 0 0.15 89.12
159 INT52954 Binding of Pdpn and Flvcr2 1 0.05 0.42 0.41 88.72
160 INT356314 Binding of Crhr1 and ORF61 1 0.00 0 0.63 87.92
161 INT72917 Binding of Crh and Crhr1 4 0.32 0.73 0.91 87.92
162 INT18026 Binding of Oprd1 and Oprm1 4 0.40 0.83 3.53 87.88
163 INT103724 Oprd1 Positive_regulation of Gtpbp4 3 0.30 0.91 4.18 87.60
164 INT103725 Negative_regulation of Oprd1 Positive_regulation of Gtpbp4 1 0.17 0.38 1.65 87.60
165 INT103726 Regulation of Oprd1 Positive_regulation of Gtpbp4 1 0.10 0.38 1.64 87.60
166 INT130786 Positive_regulation of Oprm1 Positive_regulation of Arc 1 0.27 0.9 1.31 87.16
167 INT64776 Binding of Oprm1 and Kcnj3 1 0.38 0 0.6 86.88
168 INT131314 crz Regulation of Oprl1 1 0.06 0.08 1.08 86.56
169 INT212824 WAS Positive_regulation of Cnr1 1 0.21 0.62 1.16 86.32
170 INT54239 Binding of Mme and Nts 1 0.21 0 0.54 86.24
171 INT321474 Binding of Slc6a2 and Ubqln1 1 0.00 0.8 2.27 85.96
172 INT321478 Binding of Slc6a2 and Flvcr2 1 0.00 0.41 1.14 85.96
173 INT321476 Binding of Slc6a3 and Slc6a2 1 0.01 0.41 1.14 85.96
174 INT212815 WAS Positive_regulation of CNR1 1 0.01 0.62 1.16 85.84
175 INT75374 ecs Positive_regulation of Gene_expression of Pomc 1 0.02 0.64 0.14 85.84
176 INT325391 Binding of Ghrl and Ghsr 2 0.17 0.14 0.43 85.60
177 INT128914 COMT Regulation of OPRM1 1 0.39 0.07 1.39 85.32
178 INT321477 Binding of Ubqln1 and Flvcr2 1 0.00 0.81 2.26 84.76
179 INT321473 Binding of Slc6a3 and Ubqln1 1 0.00 0.41 1.13 84.76
180 INT119713 Negative_regulation of Slc6a3 Positive_regulation of Cpu3 1 0.39 0.71 1.26 84.72
181 INT140332 RPL7AP5 Negative_regulation of Ltp 1 0.00 0.64 1.47 84.48
182 INT140329 Grin1 Negative_regulation of Ltp 1 0.04 0.64 1.46 84.48
183 INT327701 Comt Regulation of Npcd 1 0.01 0 0.29 84.48
184 INT159455 Binding of Vamp1 and Ppidl1 1 0.00 0.84 0.57 84.16
185 INT159456 Negative_regulation of Binding of Vamp1 and Ppidl1 1 0.00 0.42 0.28 84.16
186 INT66890 Binding of PENK and Oprd1 1 0.05 0 0.45 84.00
187 INT327706 Comt Regulation of Gopc 1 0.10 0 0.29 84.00
188 INT329451 Binding of Oprd1 and Tacr1 1 0.05 0.23 1.41 83.76
189 INT329452 Binding of Tac1 and Oprd1 1 0.01 0.23 1.4 83.76
190 INT159454 Binding of Inadl2 and Ppidl1 1 0.03 1.08 0.7 83.56
191 INT193562 Nr1i3 Positive_regulation of Hspg2 1 0.00 0 0.17 83.48
192 INT316632 Dao Negative_regulation of Gopc 1 0.09 0 0.4 83.00
193 INT273953 Crem Regulation of Transcription of Crh 1 0.26 0.99 0.27 82.84
194 INT172206 Binding of Slc6a3 and ADHD1 2 0.03 2.76 1.61 82.76
195 INT103000 Cpe Regulation of Penk 1 0.07 0.19 0.62 82.76
196 INT70105 SCD Positive_regulation of Oprm1 1 0.01 0 1 82.40
197 INT353372 Dio1 Positive_regulation of Grin1 1 0.16 0 0.98 82.32
198 INT184877 Negative_regulation of Binding of Slc6a3 and ADHD1 1 0.01 0.69 0.45 81.68
199 INT273935 Crem Regulation of Gene_expression of Egr2 1 0.05 0.16 0.26 81.64
200 INT337111 Positive_regulation of Nr1d2-rs2 Negative_regulation of Positive_regulation of Mapk1 1 0.00 0.15 0.31 81.52

Single Events

The table below shows the top 200 pain related interactions that have been reported for Nucleus accumbens. They are ordered first by their pain relevance and then by number of times they were reported in Nucleus accumbens. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT796 Gene_expression of Penk 1902 0.78 275.47 1057.59 100.00
2 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02 100.00
3 INT5595 Positive_regulation of Pdyn 223 0.70 48.37 130.14 100.00
4 INT24989 Positive_regulation of Cfp 125 0.61 29.55 64.9 100.00
5 INT5202 Positive_regulation of Gene_expression of Fos 1163 0.70 319.28 684 100.00
6 INT797 Regulation of Penk 812 0.62 111.13 542.24 100.00
7 INT728 Positive_regulation of Penk 1068 0.70 186.9 636.87 100.00
8 INT1316 Positive_regulation of Acot1 129 0.60 18.86 56.13 100.00
9 INT31774 Positive_regulation of Vta1 67 0.44 14.52 71.79 100.00
10 INT886 Gene_expression of Pomc 676 0.78 129.87 295.98 100.00
11 INT82055 Positive_regulation of Creb1 176 0.70 60.2 58.39 100.00
12 INT798 Positive_regulation of Gene_expression of Penk 394 0.70 78.53 203.07 100.00
13 INT18334 Positive_regulation of Cpb2 24 0.69 2.98 11.22 100.00
14 INT2780 Regulation of Gene_expression of Penk 265 0.62 32.45 143.88 100.00
15 INT145425 Positive_regulation of NLRP1 19 0.47 6.93 12.09 100.00
16 INT2651 Positive_regulation of Pomc 403 0.70 95.72 206.24 100.00
17 INT17736 Gene_expression of Cfp 111 0.65 40.68 36.61 100.00
18 INT35707 Gene_expression of Nlrp1a 20 0.75 9.61 9.32 100.00
19 INT339 Regulation of Trh 156 0.62 39.27 83.55 100.00
20 INT5506 Positive_regulation of Gene_expression of Pomc 132 0.70 26.78 54.3 100.00
21 INT5930 Positive_regulation of Oprm1 221 0.70 31.19 172.93 100.00
22 INT3766 Positive_regulation of Localization of Acot1 192 0.69 21.8 85.35 100.00
23 INT30197 Positive_regulation of Ubqln1 26 0.08 2.07 18.28 100.00
24 INT2783 Gene_expression of Slc3a1 86 0.65 8.84 45.4 100.00
25 INT5591 Regulation of Gene_expression of Fos 425 0.62 129.06 265.78 100.00
26 INT7607 Localization of Nacc1 7 0.81 0 7.09 100.00
27 INT4798 Gene_expression of Nts 169 0.77 29.56 86.04 100.00
28 INT5540 Positive_regulation of Oprm1 344 0.70 76.77 319.71 100.00
29 INT114395 Positive_regulation of Nlrp1a 15 0.45 4.61 15.37 100.00
30 INT164366 Localization of NLRP1 26 0.71 5.9 16.54 100.00
31 INT153371 Binding of Cfp 27 0.47 7.33 7.48 100.00
32 INT6436 Positive_regulation of Positive_regulation of Fos 101 0.70 18.71 57.96 100.00
33 INT605 Regulation of Acot1 61 0.62 10.7 26.34 100.00
34 INT2365 Positive_regulation of Cck 354 0.70 87.8 277.41 100.00
35 INT20575 Gene_expression of Akr1d1 48 0.57 6.2 22.5 100.00
36 INT28728 Regulation of Cfp 49 0.46 13.15 21.43 100.00
37 INT720 Positive_regulation of POMC 807 0.70 237.37 353.83 100.00
38 INT771 Regulation of Nts 93 0.61 13.13 53.57 100.00
39 INT8152 Gene_expression of Vta1 40 0.58 19.9 46.28 100.00
40 INT51627 Gene_expression of Grin2a 82 0.76 25.09 47.6 100.00
41 INT124488 Positive_regulation of Gene_expression of Plat 14 0.70 5.46 6.52 100.00
42 INT13838 Positive_regulation of Drd1a 48 0.70 9.83 23.42 100.00
43 INT54368 Positive_regulation of VTA1 13 0.59 3.81 8.13 100.00
44 INT6214 Negative_regulation of Adarb1 123 0.50 26.39 89.57 100.00
45 INT51779 Gene_expression of Drd1a 46 0.66 11.18 17.51 100.00
46 INT68304 Positive_regulation of Nacc1 11 0.70 0.76 6.45 100.00
47 INT10118 Positive_regulation of Localization of Pdyn 15 0.70 0.77 19.5 100.00
48 INT61158 Negative_regulation of Creb1 33 0.59 11.54 18.06 100.00
49 INT65390 Positive_regulation of Plat 30 0.70 23.31 9.31 100.00
50 INT5007 Gene_expression of IGHM 8 0.09 1.48 2.19 100.00
51 INT5851 Positive_regulation of Gene_expression of Penk 52 0.70 14.57 25.05 100.00
52 INT265706 Binding of IGHM 1 0.02 0.16 1.96 100.00
53 INT163054 Gene_expression of Msn 20 0.66 0.6 9.06 100.00
54 INT68789 Regulation of CFP 17 0.51 4.76 3.98 100.00
55 INT82054 Positive_regulation of Grin2b 56 0.70 17.45 37.14 100.00
56 INT17641 Gene_expression of NLRP1 33 0.73 8.85 6.02 100.00
57 INT6116 Regulation of Gene_expression of Oprd1 69 0.62 16.43 54 100.00
58 INT109264 Positive_regulation of Transcription of Th 17 0.50 4.73 14.33 100.00
59 INT73894 Positive_regulation of Localization of Trak2 1 0.69 0 2.59 100.00
60 INT22547 Regulation of Gene_expression of Casp3 23 0.62 8.04 16.78 100.00
61 INT121870 Positive_regulation of Gene_expression of Camk4 24 0.70 15.63 5.83 100.00
62 INT66611 Localization of Cfp 22 0.65 7.04 14.64 100.00
63 INT8529 Regulation of Transcription of Penk 8 0.39 1.26 5.89 100.00
64 INT125622 Regulation of NLRP1 7 0.44 1.84 3.62 100.00
65 INT7611 Positive_regulation of Cspg5 17 0.67 2.97 12.2 100.00
66 INT66960 Negative_regulation of ACACA 4 0.57 1.21 3.59 100.00
67 INT62675 Gene_expression of Nacc1 7 0.78 0.26 4.94 100.00
68 INT66867 Gene_expression of Ceacam3 58 0.67 30.44 40.7 100.00
69 INT8363 Localization of Nts 135 0.81 14.29 61.71 100.00
70 INT80470 Negative_regulation of Gene_expression of Grin1 33 0.59 10.22 27.15 100.00
71 INT114393 Positive_regulation of Vta1 15 0.29 0.75 10.64 100.00
72 INT45365 Negative_regulation of Cfp 68 0.57 25.44 32.11 100.00
73 INT15643 Positive_regulation of Positive_regulation of Pomc 30 0.65 4.59 15.34 100.00
74 INT4768 Positive_regulation of OPRM1 212 0.70 31.09 164.28 100.00
75 INT114394 Negative_regulation of Positive_regulation of Nlrp1a 4 0.42 1.09 7.37 100.00
76 INT49001 Regulation of Gria1 51 0.56 18.28 31.22 100.00
77 INT131920 Positive_regulation of Gene_expression of Nlrp1a 4 0.08 2.23 2.02 100.00
78 INT7952 Localization of Slc3a1 32 0.81 1.28 15.69 100.00
79 INT142056 Binding of NLRP1 7 0.47 1.7 2.02 100.00
80 INT74363 Negative_regulation of Nacc1 3 0.59 0.79 1.73 100.00
81 INT20345 Gene_expression of Dbi 136 0.78 56.41 46.2 100.00
82 INT5283 Positive_regulation of Npy 191 0.70 66.77 109.2 100.00
83 INT40777 Positive_regulation of Akt1 163 0.69 59.41 49.43 100.00
84 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08 100.00
85 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 100.00
86 INT13287 Gene_expression of Cpb2 27 0.56 7.84 11.95 100.00
87 INT75063 Regulation of Gene_expression of Drd2 10 0.62 2.82 7.38 100.00
88 INT100926 Positive_regulation of Gene_expression of Grin2a 11 0.63 3.24 6.41 100.00
89 INT49203 Regulation of Protein_catabolism of Cck 2 0.38 1.33 3.52 100.00
90 INT120438 Positive_regulation of Arcn1 1 0.51 0.57 0.87 100.00
91 INT7901 Positive_regulation of Ppidl1 14 0.15 1.58 8.8 100.00
92 INT107248 Negative_regulation of Gene_expression of Creb1 26 0.58 9.24 13.41 100.00
93 INT174844 Binding of Fig4 81 0.41 18.03 12.87 100.00
94 INT146343 Regulation of Slc6a3 17 0.60 7.33 8.27 100.00
95 INT6406 Binding of Oprm1 280 0.48 40.54 226.26 100.00
96 INT156268 Regulation of Nlrp1a 4 0.08 1.95 3.18 100.00
97 INT90313 Negative_regulation of Gene_expression of Casp3 57 0.57 22.23 26.77 100.00
98 INT1599 Positive_regulation of ADCY1 146 0.67 30.05 64.9 100.00
99 INT23210 Localization of Fabp6 11 0.58 6.14 5.81 100.00
100 INT6277 Positive_regulation of Gene_expression of Pomc 76 0.70 21.45 31.09 100.00
101 INT12639 Gene_expression of Gnai2 6 0.24 0.35 3.4 100.00
102 INT73895 Localization of Trak2 1 0.80 0 1.28 100.00
103 INT7956 Regulation of Gene_expression of Th 44 0.61 8.26 29.31 100.00
104 INT143317 Regulation of Gene_expression of Dio1 4 0.26 2.9 1.4 100.00
105 INT116619 Positive_regulation of Positive_regulation of Creb1 25 0.69 8.32 7.3 100.00
106 INT6748 Regulation of Dio1 15 0.45 2.63 11.18 100.00
107 INT74087 Regulation of Positive_regulation of Trak2 1 0.40 0 1.84 100.00
108 INT6623 Gene_expression of NA 231 0.78 45.78 59.36 100.00
109 INT74086 Positive_regulation of Trak2 1 0.46 0 1.83 100.00
110 INT3431 Negative_regulation of Positive_regulation of Oprl1 14 0.46 2.55 9.65 100.00
111 INT55224 Gene_expression of DRGX 99 0.31 67.55 67.63 100.00
112 INT49111 Negative_regulation of Prkaca 102 0.59 27.44 71.77 100.00
113 INT6791 Binding of NA 55 0.46 5.36 17.59 100.00
114 INT6499 Localization of Ntrk2 44 0.79 11.78 8.75 100.00
115 INT206603 Localization of Nlrp1a 9 0.16 1.37 6.57 100.00
116 INT7606 Regulation of Localization of Nacc1 1 0.22 0 1.07 100.00
117 INT18149 Negative_regulation of Binding of Nts 6 0.19 0.59 4.74 100.00
118 INT206595 Negative_regulation of Nlrp1a 1 0.06 0.5 1.25 100.00
119 INT107125 Negative_regulation of Nacc1 1 0.02 0.61 1.38 100.00
120 INT169173 Gene_expression of ocd 9 0.50 4.49 1.28 100.00
121 INT257950 Regulation of Localization of NLRP1 3 0.08 0.27 2.6 100.00
122 INT63482 Negative_regulation of Gene_expression of FOSL1 2 0.57 0 1.31 100.00
123 INT53773 Positive_regulation of Transcription of Npy 11 0.70 3.75 6.29 100.00
124 INT129950 Negative_regulation of Gene_expression of Vta1 2 0.18 1.12 2.93 100.00
125 INT169319 Regulation of Gene_expression of Nlrp1a 2 0.60 0.31 1 100.00
126 INT8380 Positive_regulation of Gene_expression of Npy 49 0.70 19.62 24.13 100.00
127 INT120441 Localization of BTF3 2 0.06 1.25 0.81 100.00
128 INT35716 Positive_regulation of NCOR2 45 0.60 18 23.54 100.00
129 INT82908 Negative_regulation of Binding of Gal 1 0.51 0.15 2.19 100.00
130 INT216666 Positive_regulation of Localization of NLRP1 2 0.09 0.5 1.49 100.00
131 INT8160 Gene_expression of Prss12 20 0.67 4.83 8.17 100.00
132 INT131689 Localization of Vta1 8 0.48 0.57 7.64 100.00
133 INT164367 Negative_regulation of Localization of NLRP1 3 0.34 1.43 2.5 100.00
134 INT164438 Gene_expression of Rabep2 1 0.32 1.21 2 100.00
135 INT164440 Gene_expression of Nacc1 1 0.05 1.2 2 100.00
136 INT9525 Regulation of Positive_regulation of Prkcg 20 0.62 7.82 16.18 100.00
137 INT102363 Negative_regulation of Positive_regulation of OPRK1 7 0.43 0.99 4.25 100.00
138 INT12636 Positive_regulation of Gene_expression of Gnai2 1 0.18 0.16 2.01 100.00
139 INT152371 Regulation of Gene_expression of Grm1 2 0.42 0.54 1.4 100.00
140 INT107656 Regulation of Gene_expression of Grm5 4 0.26 0.84 2.38 100.00
141 INT139760 Regulation of GRM2 1 0.44 0.06 0.33 100.00
142 INT134715 Regulation of Positive_regulation of Rs1 1 0.05 0 0.46 100.00
143 INT120440 Positive_regulation of Positive_regulation of BTF3 1 0.04 0.32 0.43 100.00
144 INT120439 Positive_regulation of BTF3 2 0.04 0.49 0.49 100.00
145 INT206602 Transcription of Nlrp1a 2 0.11 0.63 0.49 100.00
146 INT67329 Positive_regulation of Positive_regulation of Dll1 2 0.32 0 2.56 100.00
147 INT53891 Positive_regulation of Positive_regulation of YY1 5 0.49 0.24 3.65 100.00
148 INT197774 Positive_regulation of Binding of Fig4 3 0.08 1.46 0.4 100.00
149 INT12010 Gene_expression of Cp 38 0.65 20.55 7.84 100.00
150 INT12009 Transcription of Cp 2 0.16 0 0.46 100.00
151 INT347801 Regulation of Regulation of Dio1 1 0.15 0.55 0.39 100.00
152 INT169552 Positive_regulation of Negative_regulation of Slc6a3 3 0.50 0.51 2.05 100.00
153 INT50991 Regulation of Nacc1 3 0.05 7.25 4.7 100.00
154 INT127434 Negative_regulation of Gene_expression of Per1 12 0.58 2.58 4.2 100.00
155 INT228849 Negative_regulation of Binding of Dio1 1 0.06 0 0.36 100.00
156 INT104039 Positive_regulation of Crhr1 15 0.70 8.34 10.99 100.00
157 INT3211 Positive_regulation of Calcrl 3 0.23 0.81 0.8 100.00
158 INT119329 Positive_regulation of Ramp1 1 0.43 0.2 0.48 100.00
159 INT1295 Binding of Pomc 85 0.48 12.92 42.8 100.00
160 INT119326 Positive_regulation of Ramp2 1 0.42 0.2 0.48 100.00
161 INT117718 Positive_regulation of Phosphorylation of Akt1 112 0.69 39.26 24.09 100.00
162 INT117721 Positive_regulation of Gene_expression of Akt1 22 0.69 6.26 6.08 100.00
163 INT228843 Positive_regulation of Acss2 1 0.13 0.06 0.53 100.00
164 INT175526 Phosphorylation of Gopc 73 0.53 21.08 7.86 100.00
165 INT175531 Positive_regulation of Phosphorylation of Gopc 11 0.33 2.53 3.54 100.00
166 INT228842 Positive_regulation of Phosphorylation of Cp 1 0.09 0 0.37 100.00
167 INT165874 Phosphorylation of Cp 2 0.15 0 0.36 100.00
168 INT103878 Binding of PTGDR 9 0.48 6.22 7.23 100.00
169 INT124487 Negative_regulation of Gene_expression of Plat 4 0.43 1.88 0.55 100.00
170 INT53311 Positive_regulation of Gene_expression of Cfp 20 0.42 4.39 6.62 100.00
171 INT112707 Negative_regulation of Akt1 89 0.59 28.85 27.76 100.00
172 INT117720 Negative_regulation of Gene_expression of Akt1 11 0.37 2.33 3.08 100.00
173 INT257893 Negative_regulation of Positive_regulation of Sostdc1 1 0.01 0 0.9 100.00
174 INT197458 Positive_regulation of Sostdc1 11 0.01 3.02 4.87 100.00
175 INT48496 Regulation of Transcription of Th 16 0.54 2.29 10.02 100.00
176 INT139485 Regulation of Gene_expression of Nacc1 1 0.03 0 1.44 100.00
177 INT103740 Positive_regulation of Localization of Vta1 2 0.32 0.4 2.84 100.00
178 INT156267 Positive_regulation of Regulation of Prl5a1 1 0.05 0 1.97 100.00
179 INT156266 Regulation of Prl5a1 1 0.03 0 1.95 100.00
180 INT49835 Negative_regulation of Positive_regulation of Oprm1 21 0.42 4.11 20.11 100.00
181 INT54284 Negative_regulation of Gene_expression of Oprd1 16 0.42 4.56 14.34 100.00
182 INT103352 Positive_regulation of Binding of Ppidl1 1 0.20 0.55 0.86 100.00
183 INT100658 Negative_regulation of Positive_regulation of Grin2b 7 0.41 1.39 6.17 100.00
184 INT136001 Positive_regulation of Positive_regulation of Nacc1 1 0.38 0 0.96 100.00
185 INT206592 Negative_regulation of Localization of Nlrp1a 2 0.06 0.47 1.75 100.00
186 INT671 Positive_regulation of Cea 221 0.69 164.5 47.79 100.00
187 INT98976 Regulation of F2r 7 0.60 0.71 1.22 100.00
188 INT105749 Regulation of Onecut1 1 0.20 0.35 0.45 100.00
189 INT7885 Positive_regulation of Localization of Oxt 160 0.70 14.36 87.7 100.00
190 INT7468 Negative_regulation of Localization of Oxt 109 0.59 9.46 66.79 100.00
191 INT7884 Regulation of Localization of Oxt 102 0.62 7.95 61.71 100.00
192 INT55670 Negative_regulation of Gene_expression of Tnf 83 0.59 57.16 46.33 100.00
193 INT325976 Negative_regulation of Gene_expression of Ifi30 1 0.19 0.56 2.78 100.00
194 INT113062 Positive_regulation of Blacv1 2 0.02 0.6 2.51 100.00
195 INT144366 Negative_regulation of Positive_regulation of Gdnf 4 0.41 1.43 2.41 100.00
196 INT152025 Negative_regulation of Positive_regulation of Grm5 4 0.14 2.21 2.06 100.00
197 INT113060 Negative_regulation of Positive_regulation of Blacv1 1 0.02 0 1.64 100.00
198 INT164439 Positive_regulation of Nacc1 1 0.04 1.04 1.44 100.00
199 INT142409 Negative_regulation of Gene_expression of Fosb 3 0.41 0.48 1.09 100.00
200 INT96482 Positive_regulation of Hal 1 0.36 0 0.9 100.00
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