P:Opioid receptor

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pChart

Pain Term
Category Family
Synonyms Opioid Receptors
Pain Specific No
Documents 9408
Hot Single Events 200
Hot Interactions 200

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Opioid receptor. They are ordered first by their pain relevance and then by number of times they were reported for Opioid receptor. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT66535 Binding of Pnoc and Oprl1 43 0.54 5.93 32.4 100.00
2 INT108810 Esr1 Positive_regulation of Binding of Oprm1 1 0.51 1.79 3.22 100.00
3 INT322411 Hist1h1t Positive_regulation of Positive_regulation of OPRM1 1 0.00 1.25 3.63 100.00
4 INT322410 Hist1h1t Positive_regulation of Phosphorylation of OPRM1 1 0.00 0.08 2.31 100.00
5 INT134742 Binding of OPRM1 and SV2A 1 0.33 0.18 1.64 100.00
6 INT114927 Positive_regulation of Binding of Oprm1 and Creb1 1 0.17 0.28 2.07 100.00
7 INT114923 Binding of Oprm1 and Creb1 1 0.16 0.28 2.06 100.00
8 INT168758 Hist1h1t Positive_regulation of Phosphorylation of Akt1 2 0.02 0.44 2.79 100.00
9 INT317517 Binding of Nos1 and Oprm1 1 0.17 0.22 3.85 100.00
10 INT21276 Binding of Oprd1 and Penk 9 0.54 1.14 8.28 100.00
11 INT117008 Sfpi1 Regulation of Oprm1 1 0.56 0.56 1.49 100.00
12 INT144452 Binding of GPM6A and GPM6B 1 0.28 0 1.46 100.00
13 INT144454 Binding of DMPK and GPM6A 1 0.00 0 1.45 100.00
14 INT134284 Binding of OPRM1 and PLD2 1 0.52 0 3.72 100.00
15 INT195931 Binding of OPRM1 and Trpv1 1 0.07 0.87 3.43 100.00
16 INT157524 Binding of GRM5 and OPRM1 1 0.36 0 1.74 100.00
17 INT182704 Binding of NPFF and TP53INP2 1 0.01 0.73 3.28 100.00
18 INT317563 Binding of Hint1 and Oprm1 1 0.20 0.25 3.03 100.00
19 INT114926 Creb1 Negative_regulation of Positive_regulation of Oprm1 1 0.13 0.23 1.56 100.00
20 INT34444 Binding of Oprl1 and Ptprg 4 0.03 0.18 4.58 100.00
21 INT114929 Positive_regulation of Binding of Oprm1 and Crebbp 1 0.06 0.14 1.28 100.00
22 INT114925 Binding of Oprm1 and Crebbp 1 0.06 0.14 1.27 100.00
23 INT317551 Binding of Akt1 and Oprm1 1 0.19 0.21 2.74 100.00
24 INT153582 Binding of Oprm1 and Hint1 1 0.01 0 1.87 100.00
25 INT68514 Pnoc Positive_regulation of Oprl1 10 0.59 3.56 9.57 100.00
26 INT94367 Binding of ARRB1 and TP53INP2 1 0.25 0 1.3 100.00
27 INT113540 Binding of OPRM1 and Tac1 1 0.04 0.1 1.1 100.00
28 INT61049 Binding of Oprd1 and Negative_regulation of Gene_expression of Odc1 1 0.21 0 1.64 100.00
29 INT182706 NPFF Regulation of Binding of TP53INP2 1 0.01 0.07 1.52 100.00
30 INT117005 Sfpi1 Positive_regulation of Oprm1 1 0.52 0.56 0.94 100.00
31 INT146099 Binding of Oprm1 and Rgs9 1 0.48 0 1.95 100.00
32 INT125845 Positive_regulation of Pag1 Positive_regulation of Gene_expression of Arrb2 1 0.09 0.46 1.48 100.00
33 INT211748 Binding of Pag1 and Mors1 2 0.07 0.2 2.26 100.00
34 INT317526 Binding of Hint1 and Gipc1 1 0.00 0.25 2.38 100.00
35 INT153581 Binding of Oprm1 and Prkcg 1 0.00 0 1.44 100.00
36 INT64750 Binding of Oprm1 and Pck1 2 0.41 0.51 2.07 100.00
37 INT119917 Zfp821 Positive_regulation of Positive_regulation of Oprd1 1 0.01 0 1.82 100.00
38 INT117012 Binding of OPRD1 and TCN2 1 0.02 0 0.72 100.00
39 INT317540 Camk2a Negative_regulation of Oprm1 1 0.19 0 1.98 100.00
40 INT49955 OPRM1 Positive_regulation of ADCY1 1 0.21 0.31 1.19 100.00
41 INT49956 OPRM1 Positive_regulation of SGCG 1 0.53 0.3 1.18 100.00
42 INT72229 Binding of NFKBIL1 and BTRC 1 0.00 0 0.73 100.00
43 INT211747 Negative_regulation of Binding of Oprm1 and Mors1 1 0.09 0 1.86 100.00
44 INT211746 Binding of Oprm1 and Mors1 1 0.08 0 1.78 100.00
45 INT107738 Binding of Pld2 and Oprm1 1 0.23 0 1.93 100.00
46 INT317511 Ppp1r9b Regulation of Oprm1 3 0.27 0.33 3.85 100.00
47 INT69665 Binding of Oprd1 and Pnoc 5 0.35 0.4 2.5 100.00
48 INT108811 Esr2 Positive_regulation of Binding of Oprm1 1 0.46 0.44 0.79 100.00
49 INT153589 Binding of PRKCI and Oprm1 1 0.06 0 1.17 100.00
50 INT153588 Binding of HINT1 and Oprm1 1 0.06 0 1.17 100.00
51 INT61053 Adarb1 Positive_regulation of Pomc Negative_regulation of Odc1 1 0.01 0 1.1 100.00
52 INT65463 Bri3 Negative_regulation of Oprd1 1 0.10 0.39 0.94 100.00
53 INT157522 GRM5 Regulation of Gene_expression of OPRM1 1 0.28 0 0.97 100.00
54 INT103724 Oprd1 Positive_regulation of Gtpbp4 3 0.30 0.91 4.18 100.00
55 INT167319 Binding of OPRM1 and PCSK2 1 0.22 0.63 1.77 100.00
56 INT167320 Binding of CPE and OPRM1 1 0.14 0.63 1.77 100.00
57 INT167321 Binding of ENG and OPRM1 1 0.27 0.63 1.76 100.00
58 INT144455 Binding of CNR1 and GPM6A 1 0.02 0 0.74 100.00
59 INT144453 Binding of GPM6A and SSTR2 1 0.02 0 0.74 100.00
60 INT144459 Binding of GPM6A and INSRR 1 0.00 0 0.67 100.00
61 INT71595 Camk2a Regulation of Negative_regulation of Oprm1 1 0.04 0 0.69 100.00
62 INT18026 Binding of Oprd1 and Oprm1 4 0.40 0.83 3.53 100.00
63 INT126829 Oprm1 Positive_regulation of Rtl1 1 0.41 0 0.43 100.00
64 INT167947 Binding of STAT1 and Oprm1 1 0.00 0 0.86 100.00
65 INT167944 Binding of Oprm1 and Stat5a 1 0.00 0 0.85 100.00
66 INT88778 Binding of Oprm1 and Pomc 3 0.21 0.56 1.14 100.00
67 INT123416 Gene_expression of Sp1 Positive_regulation of Oprm1 1 0.60 0 0.63 100.00
68 INT108812 Esr1 Positive_regulation of Positive_regulation of Oprm1 1 0.42 0.38 0.78 100.00
69 INT317519 Grin1 Positive_regulation of Negative_regulation of Oprm1 1 0.14 0 1.31 100.00
70 INT114924 Creb1 Regulation of Positive_regulation of Oprm1 1 0.09 0.13 0.79 100.00
71 INT117707 Oprm1 Positive_regulation of PIK3CG 1 0.00 0.08 0.6 100.00
72 INT114921 Binding of Oprm1 and Creb1 Positive_regulation of Positive_regulation of Oprm1 1 0.06 0.05 0.54 100.00
73 INT114928 Positive_regulation of Creb1 Positive_regulation of Positive_regulation of Oprm1 1 0.16 0.05 0.54 100.00
74 INT117007 Binding of Oprm1 and Sfpi1 1 0.50 0.07 0.63 100.00
75 INT121089 Binding of Oprd1 and Adarb1 2 0.06 0 1.07 100.00
76 INT114930 Binding of Oprm1 and Crebbp Positive_regulation of Positive_regulation of Creb1 1 0.06 0 0.51 100.00
77 INT114931 Binding of Oprm1 and Creb1 Positive_regulation of Positive_regulation of Creb1 1 0.16 0 0.51 100.00
78 INT322385 PPBP Negative_regulation of Positive_regulation of OPRM1 1 0.00 0 0.64 100.00
79 INT302119 Positive_regulation of Binding of Oprm1 and Ppp1r9b 1 0.02 0 0.77 100.00
80 INT87375 Binding of Gabrg1 and Oprm1 1 0.00 0.83 1.25 100.00
81 INT302118 Binding of Oprm1 and Ppp1r9b 2 0.24 0.26 3.45 100.00
82 INT69337 Oprm1 Positive_regulation of Atxn2l 1 0.01 0.27 1.43 100.00
83 INT110542 SIGMAR1 Regulation of OPRM1 1 0.04 0.33 1.25 100.00
84 INT110543 SIGMAR1 Regulation of Gene_expression of OPRM1 1 0.04 0.33 1.25 100.00
85 INT137230 Trh Regulation of Gene_expression of Oprd1 1 0.01 1.62 2.75 100.00
86 INT124157 Oprm1 Negative_regulation of Gnb5 1 0.25 0.4 1.19 100.00
87 INT249566 Binding of Oprd1 and Psmd1 1 0.01 0.82 3.8 100.00
88 INT52114 Oprd1 Regulation of ADCY1 2 0.05 0.46 0.9 100.00
89 INT126615 Binding of Oprd1 and Stat5a 1 0.28 0.07 0.61 100.00
90 INT6466 Binding of Npr1 and Oprd1 1 0.01 0 1.37 100.00
91 INT322397 Egfr Positive_regulation of Adarb1 1 0.00 0.08 0.8 100.00
92 INT144456 Binding of GPM6A and OPRM1 1 0.07 0 0.5 100.00
93 INT133075 TFAM Positive_regulation of Transcription of OPRM1 1 0.03 0 1.04 100.00
94 INT133072 GATA3 Positive_regulation of Transcription of OPRM1 1 0.35 0 1.04 100.00
95 INT160590 CSF2 Positive_regulation of Gene_expression of OPRM1 1 0.16 0.54 1.35 100.00
96 INT160586 IL6 Positive_regulation of Gene_expression of OPRM1 1 0.14 0.54 1.35 100.00
97 INT160588 TNF Positive_regulation of Gene_expression of OPRM1 1 0.20 0.54 1.35 100.00
98 INT160587 IFNG Positive_regulation of Gene_expression of OPRM1 1 0.18 0.54 1.35 100.00
99 INT160585 IL18 Positive_regulation of Gene_expression of OPRM1 1 0.09 0.54 1.35 100.00
100 INT160589 IL4 Positive_regulation of Gene_expression of OPRM1 1 0.13 0.54 1.35 100.00
101 INT142852 Oprm1 Positive_regulation of Oprd1 1 0.41 0.06 1.41 100.00
102 INT338392 Thim Negative_regulation of Mors1 1 0.01 0.4 0.69 100.00
103 INT96462 Pnoc Positive_regulation of Pag1 1 0.01 0.74 2.45 100.00
104 INT96465 Pnoc Positive_regulation of GEM 1 0.01 0.74 2.39 100.00
105 INT96461 Pnoc Positive_regulation of Oprm1 1 0.09 0.73 2.34 100.00
106 INT65724 Binding of Pnoc and Oprl1 8 0.33 2.94 8.82 100.00
107 INT106956 Oprm1 Positive_regulation of Positive_regulation of P9Ehs1 1 0.08 0.54 1.02 100.00
108 INT69338 Binding of Oprd1 and Oprm1 1 0.24 0.26 1.11 100.00
109 INT72230 Binding of BTRC and EMID1 1 0.00 0 0.49 100.00
110 INT72227 Binding of BTRC and AP1M2 1 0.00 0 0.49 100.00
111 INT94366 Binding of ARRB1 and OPRD1 1 0.11 0 0.67 100.00
112 INT82126 CEBPB Regulation of Gene_expression of Oprd1 1 0.00 0 0.93 100.00
113 INT317509 Oprm1 Negative_regulation of Phosphorylation of Oprd1 1 0.00 0 1.46 100.00
114 INT133076 STAT6 Positive_regulation of OPRM1 1 0.38 0 0.95 100.00
115 INT146097 Positive_regulation of Binding of Rgs9 and Arrb2 1 0.28 0 1.04 100.00
116 INT146098 Binding of Rgs9 and Arrb2 1 0.19 0 1.03 100.00
117 INT59446 Rbm39 Positive_regulation of Negative_regulation of Pomc 1 0.03 0.19 1.32 100.00
118 INT90046 Oprm1 Positive_regulation of P9Ehs1 2 0.16 0.92 1.63 100.00
119 INT82125 IK Regulation of Gene_expression of Oprd1 1 0.00 0 0.88 100.00
120 INT82124 IK Positive_regulation of Gene_expression of Oprd1 1 0.00 0 0.92 100.00
121 INT145906 Elane Regulation of Transcription of Oprm1 1 0.10 0.14 1.04 100.00
122 INT162164 ARF6 Regulation of Positive_regulation of PLD2 1 0.60 0 0.74 100.00
123 INT211743 Positive_regulation of Binding of Pag1 and Mors1 1 0.09 0.1 1.25 100.00
124 INT117006 Sfpi1 Negative_regulation of Oprm1 1 0.39 0.29 0.49 100.00
125 INT162162 ARF6 Regulation of OPRM1 1 0.19 0 0.71 100.00
126 INT317558 Binding of Oprm1 and Rgs17 1 0.18 0 1.59 100.00
127 INT61046 Oprm1 Positive_regulation of Gh1 1 0.21 0 0.89 100.00
128 INT61047 Oprm1 Positive_regulation of Localization of Gh1 1 0.29 0 0.89 100.00
129 INT61048 Oprm1 Positive_regulation of Localization of Prl 1 0.16 0 0.88 100.00
130 INT61045 Oprm1 Positive_regulation of Prl 1 0.16 0 0.88 100.00
131 INT56859 Oprd1 Positive_regulation of OPRD1 1 0.01 0.22 0.61 100.00
132 INT118859 GNA14 Positive_regulation of STAT3 1 0.01 0.38 1.03 100.00
133 INT317529 Binding of Hint1 and Rgs17 1 0.32 0.07 0.98 100.00
134 INT317550 Binding of Hint1 and Rgs20 1 0.32 0.07 0.98 100.00
135 INT89647 OPRM1 Regulation of ADCY1 1 0.09 0.09 0.47 100.00
136 INT57263 Binding of Oprd1 and Atxn2l 1 0.02 0 1.29 100.00
137 INT57262 Binding of Gria4 and Oprd1 1 0.06 0 1.29 100.00
138 INT161865 Mors1 Positive_regulation of Prkcg 1 0.00 0.12 1.47 100.00
139 INT161871 Mors1 Positive_regulation of GRIN1 1 0.01 0.12 1.46 100.00
140 INT161870 OPRM1 Positive_regulation of Prkcg 1 0.01 0.12 1.47 100.00
141 INT161858 OPRM1 Positive_regulation of GRIN1 1 0.50 0.12 1.45 100.00
142 INT161860 OPRM1 Positive_regulation of OPRM1 Positive_regulation of GRIN1 1 0.56 0.12 1.45 100.00
143 INT121464 Negative_regulation of Oprm1 Positive_regulation of Dnm2 1 0.34 0 1.26 100.00
144 INT322409 Positive_regulation of OPRM1 Positive_regulation of Phosphorylation of Akt1 1 0.04 0 0.4 100.00
145 INT121465 Binding of Dnm2 and Oprm1 1 0.23 0 1.24 100.00
146 INT317513 Oprm1 Regulation of Positive_regulation of Src 1 0.09 0.4 0.82 100.00
147 INT13940 DNM2 Regulation of Localization of CGA 1 0.11 0 1.86 100.00
148 INT317570 Oprm1 Regulation of Src 1 0.04 0.4 0.82 100.00
149 INT317546 Oprm1 Regulation of Prkca 1 0.06 0.4 0.82 100.00
150 INT317573 Binding of Oprm1 and Pik3r1 1 0.12 0.33 0.71 100.00
151 INT249567 Positive_regulation of Binding of Oprd1 and Psmd1 1 0.01 0.66 2.5 100.00
152 INT146096 Positive_regulation of Binding of Oprm1 and Rgs9 1 0.44 0 0.94 100.00
153 INT107331 Binding of PPBP and Adarb1 1 0.01 0 3.67 100.00
154 INT91271 Mtr Regulation of Gene_expression of Il6 1 0.20 0 3.17 100.00
155 INT317559 Binding of Hint1 and Pla2g4a 1 0.01 0.06 0.94 100.00
156 INT112842 Positive_regulation of Binding of Pdyn and Oprd1 1 0.00 0 0.81 100.00
157 INT112841 Binding of Pdyn and Oprd1 1 0.00 0 0.81 100.00
158 INT52390 OPRD1 Regulation of ADCY1 1 0.09 0.13 0.86 100.00
159 INT165317 Oprd1 Positive_regulation of Gene_expression of Oprk1 1 0.30 0.24 0.6 100.00
160 INT63407 Binding of Oprl1 and Pck1 1 0.40 0 1.29 100.00
161 INT121812 IL6 Regulation of OPRM1 1 0.22 0.27 0.65 100.00
162 INT317523 Oprm1 Positive_regulation of Gene_expression of Akt1 1 0.32 0.05 0.53 100.00
163 INT317574 Oprm1 Positive_regulation of Akt1 1 0.22 0.05 0.52 100.00
164 INT317565 Oprm1 Positive_regulation of Pik3r1 1 0.14 0.05 0.52 100.00
165 INT317512 Binding of Oprm1 and Prkca 1 0.07 0.13 1.1 100.00
166 INT7049 Binding of YY1 and Oprd1 1 0.01 0 0.73 100.00
167 INT63864 Oprd1 Regulation of Localization of Prl 2 0.16 0 1.23 100.00
168 INT9546 Binding of Adarb1 and Penk 5 0.03 0 5.1 100.00
169 INT69562 Positive_regulation of AP2M1 Positive_regulation of Regulation of Adrb3 1 0.01 0.19 1.24 100.00
170 INT317516 Binding of Oprm1 and Negative_regulation of Positive_regulation of Akt1 1 0.17 0.1 1.11 100.00
171 INT317527 Binding of Hint1 and Nos1 1 0.27 0.1 1.11 100.00
172 INT51205 Binding of OPRK1 and PDYN 7 0.00 2.01 7.8 100.00
173 INT121813 IL6 Positive_regulation of OPRM1 1 0.28 0.28 0.58 100.00
174 INT21286 Binding of Oprd1 and Pck1 1 0.08 0 0.34 100.00
175 INT317554 Akt1 Regulation of Negative_regulation of Oprm1 1 0.21 0.07 1 100.00
176 INT317532 Grin1 Regulation of Negative_regulation of Oprm1 1 0.18 0.07 1 100.00
177 INT317518 Src Regulation of Negative_regulation of Oprm1 1 0.16 0.07 1 100.00
178 INT317555 Nos1 Regulation of Negative_regulation of Oprm1 1 0.21 0.07 1 100.00
179 INT317544 Camk2a Regulation of Negative_regulation of Oprm1 1 0.20 0.07 1 100.00
180 INT317564 Pik3r1 Regulation of Negative_regulation of Oprm1 1 0.13 0.07 1 100.00
181 INT317568 Prkca Regulation of Negative_regulation of Oprm1 1 0.10 0.07 1 100.00
182 INT195929 Binding of OPRM1 and Prkaca 1 0.02 0.33 1.27 100.00
183 INT83418 Binding of OPRL1 and Ntrk1 1 0.02 0 1.91 100.00
184 INT113972 Regulation of Binding of Oprd1 and Smu1 1 0.00 0.45 0.84 100.00
185 INT113971 Binding of Oprd1 and Smu1 1 0.00 0.45 0.84 100.00
186 INT149169 Binding of Oprm1 and Atxn2l 1 0.07 0 0.5 100.00
187 INT317530 Negative_regulation of Binding of Nos1 and Oprm1 1 0.21 0.06 0.9 100.00
188 INT317514 Akt1 Regulation of Localization of Oprm1 1 0.21 0.07 0.82 100.00
189 INT157063 SLC12A1 Negative_regulation of CALCRL 1 0.00 0.34 0.73 100.00
190 INT98002 Positive_regulation of Oprm1 Positive_regulation of P9Ehs1 1 0.10 0 1 100.00
191 INT8734 Pebp1 Positive_regulation of Oprd1 1 0.01 0 1.54 100.00
192 INT148821 Binding of Oprm1 and Grin1 1 0.05 0.24 1.55 100.00
193 INT148820 Binding of Oprm1 and Naa15 1 0.02 0.24 1.55 100.00
194 INT317561 Binding of Grin1 and Oprm1 1 0.14 0.09 1.08 100.00
195 INT113537 Binding of OPRM1 and TACR1 1 0.01 0.1 0.42 100.00
196 INT124404 Binding of POMC and Oprm1 1 0.00 0.25 0.75 100.00
197 INT101716 JUND Regulation of Regulation of OPRM1 1 0.09 0.06 0.65 100.00
198 INT134114 Gnai2 Positive_regulation of Oprd1 Regulation of ADCY1 1 0.00 0.47 0.41 100.00
199 INT64217 Oprm1 Positive_regulation of Oprd1 1 0.24 0 0.46 100.00
200 INT116093 OPRM1 Positive_regulation of Positive_regulation of NFKB1 1 0.36 0.08 1.56 100.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Opioid receptor. They are ordered first by their pain relevance and then by number of times they were reported in Opioid receptor. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT5895 Gene_expression of Oprm1 525 0.78 120.67 407.29 100.00
2 INT5660 Binding of Oprd1 477 0.48 71.86 342.06 100.00
3 INT5979 Gene_expression of Oprd1 428 0.78 75.64 320.32 100.00
4 INT5540 Positive_regulation of Oprm1 344 0.70 76.77 319.71 100.00
5 INT11624 Gene_expression of OPRM1 445 0.78 72.36 294.36 100.00
6 INT6406 Binding of Oprm1 280 0.48 40.54 226.26 100.00
7 INT4941 Positive_regulation of Oprd1 345 0.70 74.26 304.41 100.00
8 INT5501 Regulation of Oprd1 283 0.62 55.1 249.9 100.00
9 INT6293 Gene_expression of Oprm1 312 0.78 48.73 215.61 100.00
10 INT4768 Positive_regulation of OPRM1 212 0.70 31.09 164.28 100.00
11 INT4937 Negative_regulation of Oprd1 224 0.59 44.51 171.11 100.00
12 INT12602 Negative_regulation of Oprm1 190 0.59 36.11 177.85 100.00
13 INT26472 Regulation of Oprm1 191 0.62 35.84 173.1 100.00
14 INT4658 Binding of OPRM1 188 0.48 25.96 136.24 100.00
15 INT5930 Positive_regulation of Oprm1 221 0.70 31.19 172.93 100.00
16 INT6042 Binding of Oprm1 248 0.48 31.77 154.34 100.00
17 INT5931 Regulation of Oprm1 149 0.62 18.15 125.93 100.00
18 INT76660 Gene_expression of Trpv1 691 0.78 329.46 386.42 100.00
19 INT5906 Negative_regulation of Oprm1 125 0.59 19.58 101.57 100.00
20 INT68813 Transcription of Oprm1 93 0.71 20.11 57.65 100.00
21 INT12569 Localization of Oprd1 94 0.81 23.81 104.56 100.00
22 INT32718 Gene_expression of OPRD1 82 0.76 9.43 48.38 100.00
23 INT49431 Phosphorylation of OPRM1 31 0.82 2.2 29.09 100.00
24 INT1639 Negative_regulation of OPRM1 107 0.59 13.86 90.37 100.00
25 INT21560 Positive_regulation of Binding of Oprm1 30 0.50 7.16 32.95 100.00
26 INT796 Gene_expression of Penk 1902 0.78 275.47 1057.59 100.00
27 INT8733 Localization of Oprm1 61 0.75 7.55 64.61 100.00
28 INT7828 Positive_regulation of Oprd1 55 0.69 14.11 42.86 100.00
29 INT7528 Regulation of OPRM1 100 0.62 20.63 80.57 100.00
30 INT62521 Phosphorylation of Oprm1 44 0.82 2.66 47.45 100.00
31 INT6656 Gene_expression of YY1 135 0.75 24.73 72.16 100.00
32 INT49747 Transcription of Oprm1 68 0.72 9.01 53.78 100.00
33 INT6116 Regulation of Gene_expression of Oprd1 69 0.62 16.43 54 100.00
34 INT117713 Phosphorylation of Akt1 275 0.82 95.82 54.34 100.00
35 INT8732 Positive_regulation of Gene_expression of Oprm1 76 0.70 22.59 58.83 100.00
36 INT10668 Positive_regulation of Gene_expression of Oprd1 61 0.69 15.21 52.12 100.00
37 INT69484 Positive_regulation of Gene_expression of OPRM1 75 0.70 12.86 52.27 100.00
38 INT29971 Gene_expression of Oprk1 126 0.78 35.32 93.97 100.00
39 INT91787 Phosphorylation of Mors1 3 0.43 1.17 41.14 100.00
40 INT12397 Gene_expression of Oprd1 53 0.78 9.1 31.31 100.00
41 INT1564 Localization of OPRM1 41 0.80 8.03 44.67 100.00
42 INT88081 Negative_regulation of Gene_expression of Oprm1 45 0.59 16.56 37.5 100.00
43 INT83419 Gene_expression of Mors1 57 0.68 12.11 63.66 100.00
44 INT34465 Regulation of Oprd1 34 0.45 7.14 34.29 100.00
45 INT15000 Transcription of Oprd1 32 0.72 5.7 29.22 100.00
46 INT108726 Binding of Mors1 38 0.33 7.08 43.62 100.00
47 INT1614 Gene_expression of Oprl1 164 0.78 31.43 127.74 100.00
48 INT20964 Gene_expression of OPRK1 96 0.78 23.54 58.18 100.00
49 INT18032 Positive_regulation of Oprk1 108 0.70 30.78 89.7 100.00
50 INT292 Localization of Penk 876 0.81 88.44 669.14 100.00
51 INT797 Regulation of Penk 812 0.62 111.13 542.24 100.00
52 INT69483 Transcription of OPRM1 45 0.72 7.31 30.22 100.00
53 INT768 Positive_regulation of Oprl1 179 0.70 40.05 156.93 100.00
54 INT6437 Binding of YY1 154 0.47 26.3 90.46 100.00
55 INT1396 Binding of Penk 355 0.48 22.79 269.65 100.00
56 INT4153 Binding of Insrr 109 0.40 17.99 72.15 100.00
57 INT88293 Localization of Mors1 25 0.39 2.18 28.72 100.00
58 INT48907 Positive_regulation of Gene_expression of Oprm1 53 0.69 8.55 33.52 100.00
59 INT6585 Positive_regulation of Insrr 110 0.52 40.67 89.9 100.00
60 INT1212 Binding of Oprl1 312 0.48 28.6 225.15 100.00
61 INT6067 Positive_regulation of Positive_regulation of Oprd1 37 0.69 6.56 36.58 100.00
62 INT30386 Negative_regulation of OPRD1 33 0.52 4.34 23.06 100.00
63 INT72677 Regulation of Gene_expression of Oprm1 45 0.62 13.95 26.75 100.00
64 INT80883 Positive_regulation of Phosphorylation of OPRM1 13 0.69 1.03 13.65 100.00
65 INT32753 Positive_regulation of Positive_regulation of OPRM1 19 0.62 3.3 16.73 100.00
66 INT1414 Regulation of Oprl1 169 0.62 32.05 139.99 100.00
67 INT16769 Positive_regulation of Positive_regulation of Oprm1 31 0.57 8.29 29.66 100.00
68 INT27529 Phosphorylation of Oprd1 23 0.47 1.16 20.18 100.00
69 INT211725 Positive_regulation of Phosphorylation of Mors1 1 0.31 0.23 23.69 100.00
70 INT728 Positive_regulation of Penk 1068 0.70 186.9 636.87 100.00
71 INT77407 Regulation of Gene_expression of OPRM1 51 0.62 12.58 35.75 100.00
72 INT5771 Binding of Oprd1 37 0.48 2.6 27.54 100.00
73 INT2640 Gene_expression of Pomc 424 0.78 120.72 155.37 100.00
74 INT5690 Negative_regulation of Binding of Oprd1 36 0.59 8.29 24.52 100.00
75 INT117718 Positive_regulation of Phosphorylation of Akt1 112 0.69 39.26 24.09 100.00
76 INT6382 Regulation of Binding of Oprd1 36 0.61 7 26.48 100.00
77 INT12763 Phosphorylation of Prkcg 167 0.82 38.91 89.63 100.00
78 INT6934 Binding of OPRD1 51 0.48 7.72 25.73 100.00
79 INT3439 Localization of Abat 1017 0.78 112.39 727.06 100.00
80 INT14137 Localization of Oprm1 56 0.81 2.88 36.09 100.00
81 INT53015 Gene_expression of TP53INP2 50 0.78 9.05 26.23 100.00
82 INT61665 Phosphorylation of Trh 53 0.79 2.26 23.9 100.00
83 INT929 Positive_regulation of Oprl1 64 0.70 14.67 52.84 100.00
84 INT49835 Negative_regulation of Positive_regulation of Oprm1 21 0.42 4.11 20.11 100.00
85 INT124144 Negative_regulation of Mors1 21 0.41 2.87 24.71 100.00
86 INT1319 Gene_expression of Oprl1 65 0.78 9.34 42.41 100.00
87 INT57253 Negative_regulation of Binding of Oprm1 24 0.43 5.27 22.67 100.00
88 INT1160 Positive_regulation of Rbm39 122 0.57 28.19 90.28 100.00
89 INT1303 Negative_regulation of Npr1 278 0.55 35.1 156.78 100.00
90 INT68811 Regulation of Transcription of Oprm1 19 0.61 3.67 15.15 100.00
91 INT114 Binding of Oprl1 139 0.48 23 103.35 100.00
92 INT66779 Binding of Pnoc 79 0.48 6.43 60.46 100.00
93 INT1295 Binding of Pomc 85 0.48 12.92 42.8 100.00
94 INT40777 Positive_regulation of Akt1 163 0.69 59.41 49.43 100.00
95 INT33209 Positive_regulation of Binding of OPRM1 8 0.68 0.63 8.95 100.00
96 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 100.00
97 INT13290 Binding of Atxn2l 34 0.18 1.86 28.16 100.00
98 INT17915 Gene_expression of Insr 141 0.75 47.45 48.59 100.00
99 INT1335 Negative_regulation of Oprl1 123 0.59 18.02 77.13 100.00
100 INT12471 Regulation of Insrr 52 0.35 17.8 48.31 100.00
101 INT1395 Negative_regulation of Penk 537 0.59 87.33 389.81 100.00
102 INT789 Positive_regulation of YY1 69 0.67 14.07 47.06 100.00
103 INT4637 Binding of Adarb1 132 0.41 14.48 67.76 100.00
104 INT21105 Phosphorylation of Oprm1 32 0.82 0.83 19.29 100.00
105 INT10304 Binding of OPRK1 89 0.48 9.28 49.42 100.00
106 INT31905 Positive_regulation of Binding of Oprd1 21 0.66 3.31 18.44 100.00
107 INT59766 Positive_regulation of Negative_regulation of Oprm1 9 0.50 1.31 11.08 100.00
108 INT49171 Gene_expression of Nos1 241 0.78 140.7 104.76 100.00
109 INT5770 Binding of Rbm39 88 0.41 13.23 55.5 100.00
110 INT695 Binding of POMC 304 0.48 56.66 126.85 100.00
111 INT77408 Binding of ARRB1 11 0.36 0.31 6.51 100.00
112 INT6179 Binding of Oprk1 37 0.48 9.24 24.83 100.00
113 INT6294 Regulation of Gene_expression of Oprm1 28 0.62 6.77 22.79 100.00
114 INT79093 Positive_regulation of Nos1 101 0.70 46.89 59.61 100.00
115 INT31186 Negative_regulation of Insrr 81 0.37 24.91 55.94 100.00
116 INT103666 Regulation of Mors1 20 0.28 3.6 18.86 100.00
117 INT5704 Binding of Slc3a1 78 0.43 8.52 51.78 100.00
118 INT11012 Positive_regulation of Creb1 258 0.70 84.4 132 100.00
119 INT12658 Regulation of Binding of Oprm1 9 0.57 2.44 14.95 100.00
120 INT12475 Gene_expression of OPRL1 35 0.77 3.63 23.11 100.00
121 INT54062 Transcription of Oprd1 11 0.68 1.05 6.65 100.00
122 INT29352 Negative_regulation of Oprd1 16 0.58 6.51 14.6 100.00
123 INT1652 Regulation of Pomc 387 0.62 61.01 186.51 100.00
124 INT87686 Positive_regulation of Gene_expression of Trpv1 101 0.70 72.41 69.15 100.00
125 INT12501 Positive_regulation of Adarb1 166 0.58 36.94 118.92 100.00
126 INT1425 Gene_expression of Rbm39 143 0.58 51.32 65.44 100.00
127 INT8332 Positive_regulation of OPRD1 30 0.61 3.88 17.65 100.00
128 INT106525 Phosphorylation of Akt1 436 0.82 183.81 47.82 100.00
129 INT66531 Gene_expression of Pnoc 88 0.78 22.9 65.11 100.00
130 INT87794 Positive_regulation of Mors1 19 0.38 4.74 20.23 100.00
131 INT1665 Positive_regulation of Pag1 270 0.68 186.63 229.87 100.00
132 INT98835 Positive_regulation of Transcription of Oprm1 15 0.65 2.47 8.67 100.00
133 INT54284 Negative_regulation of Gene_expression of Oprd1 16 0.42 4.56 14.34 100.00
134 INT64159 Gene_expression of Prkca 90 0.78 34.65 55.97 100.00
135 INT68814 Positive_regulation of Transcription of Oprm1 16 0.60 2.72 13.57 100.00
136 INT5311 Regulation of Negative_regulation of Oprd1 11 0.43 0.99 7.23 100.00
137 INT91575 Positive_regulation of Phosphorylation of Oprd1 8 0.02 0.23 6.07 100.00
138 INT29477 Transcription of Oprl1 52 0.72 5.05 30.52 100.00
139 INT58495 Positive_regulation of Positive_regulation of Oprm1 22 0.49 2.44 17.66 100.00
140 INT33915 Regulation of Positive_regulation of Oprm1 22 0.60 2.44 16.43 100.00
141 INT5852 Gene_expression of Penk 167 0.78 44.44 71.13 100.00
142 INT101721 Positive_regulation of Transcription of OPRM1 8 0.48 1.22 7.74 100.00
143 INT64161 Positive_regulation of Prkca 213 0.70 85.06 129.91 100.00
144 INT76162 Positive_regulation of Phosphorylation of Oprm1 11 0.69 0.64 8.72 100.00
145 INT48006 Negative_regulation of Oprk1 27 0.58 10.14 19.11 100.00
146 INT211732 Positive_regulation of Localization of Mors1 7 0.23 0.11 11.81 100.00
147 INT6043 Negative_regulation of Binding of Oprm1 24 0.57 2.67 16.78 100.00
148 INT16654 Gene_expression of Insrr 138 0.46 58.96 75.68 100.00
149 INT6214 Negative_regulation of Adarb1 123 0.50 26.39 89.57 100.00
150 INT127237 Phosphorylation of Prkcc 7 0.81 0 5.96 100.00
151 INT65078 Negative_regulation of Pnoc 64 0.59 15.48 59.81 100.00
152 INT5610 Positive_regulation of Insr 140 0.69 37.26 86.24 100.00
153 INT203 Positive_regulation of Pomc 257 0.70 90.56 92.84 100.00
154 INT40811 Binding of OPRL1 26 0.48 2.76 18.68 100.00
155 INT5127 Localization of Lhb 488 0.80 50.48 162.66 100.00
156 INT5379 Gene_expression of Fos 656 0.78 255.5 292.54 100.00
157 INT110017 Phosphorylation of Nos1 12 0.60 1.64 10.3 100.00
158 INT27118 Regulation of Binding of OPRM1 10 0.62 1.18 5.97 100.00
159 INT29107 Regulation of Oprk1 31 0.45 6.16 26.61 100.00
160 INT159 Negative_regulation of Localization of Prl 416 0.59 55.34 171.8 100.00
161 INT169926 Positive_regulation of Gopc 416 0.46 157.8 58.67 100.00
162 INT4769 Regulation of OPRD1 20 0.44 2.05 15.97 100.00
163 INT943 Negative_regulation of Cck 205 0.59 38.42 174.78 100.00
164 INT120966 Positive_regulation of Pik3cb 34 0.68 15.15 16.59 100.00
165 INT6165 Gene_expression of Adarb1 85 0.58 18.39 51.03 100.00
166 INT9781 Binding of INSRR 64 0.31 19.1 25.2 100.00
167 INT105381 Binding of NPFF 4 0.48 1.07 7.48 100.00
168 INT7845 Regulation of OPRK1 44 0.62 4.54 30.49 100.00
169 INT114729 Phosphorylation of Camk2a 110 0.82 15.49 33.19 100.00
170 INT6066 Negative_regulation of Positive_regulation of Oprd1 15 0.43 1.36 16.63 100.00
171 INT162 Regulation of Prl 794 0.62 165.01 322.24 100.00
172 INT1456 Regulation of Oprl1 61 0.62 19.5 52.87 100.00
173 INT121815 Regulation of Positive_regulation of OPRM1 7 0.62 0.75 7.36 100.00
174 INT76863 Negative_regulation of Gene_expression of OPRM1 21 0.57 6.56 13.69 100.00
175 INT6855 Binding of NCOR2 71 0.41 15.64 28.96 100.00
176 INT9298 Positive_regulation of Gtpbp4 64 0.69 12.29 41.97 100.00
177 INT1163 Negative_regulation of Rbm39 64 0.29 16.8 34.74 100.00
178 INT2106 Regulation of Localization of LH 279 0.62 22.37 122.77 100.00
179 INT13363 Binding of NFKBIL1 23 0.08 2.65 13.09 100.00
180 INT4803 Transcription of Penk 435 0.72 59.09 182.4 100.00
181 INT5513 Negative_regulation of Pomc 295 0.59 60.9 158.63 100.00
182 INT5591 Regulation of Gene_expression of Fos 425 0.62 129.06 265.78 100.00
183 INT88601 Regulation of Positive_regulation of P9Ehs1 10 0.15 2.6 7.36 100.00
184 INT416 Regulation of LH 253 0.62 31.48 125.55 100.00
185 INT55859 Binding of Dll1 6 0.35 0 7.64 100.00
186 INT317508 Binding of Hint1 1 0.40 1.37 6.31 100.00
187 INT93490 Gene_expression of GPM6A 14 0.69 3.14 9.08 100.00
188 INT5791 Positive_regulation of Positive_regulation of Rbm39 13 0.25 1.61 9.88 100.00
189 INT6765 Localization of Oprl1 49 0.81 5.11 28.87 100.00
190 INT74962 Phosphorylation of OPRD1 5 0.82 0.18 3.26 100.00
191 INT33099 Negative_regulation of INSRR 32 0.40 13.82 9.85 100.00
192 INT91462 Positive_regulation of Phosphorylation of MAPK1 99 0.67 40.28 18.99 100.00
193 INT15296 Regulation of Rbm39 45 0.29 10.66 29.27 100.00
194 INT16033 Gene_expression of Ogfr 27 0.73 4.15 13.05 100.00
195 INT87607 Positive_regulation of Prkcc 25 0.69 6.06 22.78 100.00
196 INT54060 Regulation of Transcription of Oprd1 3 0.57 0.59 3.18 100.00
197 INT143964 Positive_regulation of Phosphorylation of Trh 10 0.20 0.1 10.54 100.00
198 INT47876 Binding of Pnoc 20 0.47 4.99 20.01 100.00
199 INT77404 Gene_expression of ARRB1 19 0.62 1.53 7.22 100.00
200 INT6044 Regulation of Binding of Oprm1 16 0.61 3.01 11.11 100.00
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