P:Pain matrix

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pChart

Pain Term
Category Other
Synonyms None
Pain Specific Yes
Documents 103
Hot Single Events 21
Hot Interactions 2

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Pain matrix. They are ordered first by their pain relevance and then by number of times they were reported for Pain matrix. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT346986 Binding of SHC3 and PAG1 1 0.35 1.02 1.12 93.68
2 INT290821 CRX Positive_regulation of Cort 1 0.14 0.51 0.41 88.72
3 INT236491 GCH1 Regulation of Pain1 1 0.01 0.89 1.65 5.00
4 INT236489 Gtf3a Regulation of Pain1 1 0.00 0.52 0.56 5.00
5 INT236492 Gtf3a Regulation of SNRNP70 1 0.00 0.52 0.56 5.00
6 INT283948 SALL1 Positive_regulation of Positive_regulation of Ptgfrn 1 0.00 0.21 0.22 5.00
7 INT283947 Positive_regulation of Car1 Positive_regulation of Ptgfrn 1 0.01 0 0.14 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Pain matrix. They are ordered first by their pain relevance and then by number of times they were reported in Pain matrix. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT4297 Negative_regulation of CFP 21 0.42 12.7 10.29 98.96
2 INT193663 Binding of Pain1 9 0.36 8.84 8.04 97.68
3 INT62681 Negative_regulation of LEP 93 0.59 66.97 15.77 97.52
4 INT61948 Positive_regulation of FYN 4 0.45 2.49 1.19 93.44
5 INT168189 Positive_regulation of PLXNA2 1 0.20 0.49 0.75 93.44
6 INT46168 Positive_regulation of Sepp1 12 0.50 8.02 7.47 92.64
7 INT19771 Positive_regulation of PAG1 69 0.61 75.61 76.88 92.48
8 INT127565 Positive_regulation of ENC1 2 0.39 11.67 11.82 91.48
9 INT7786 Positive_regulation of Ptgdr 26 0.47 5.62 14.99 91.16
10 INT7787 Positive_regulation of Akr1d1 52 0.66 3.55 31.71 90.68
11 INT10085 Regulation of Cort 8 0.39 2.99 2.63 90.16
12 INT115391 Gene_expression of Cort 18 0.59 9.43 6.53 89.68
13 INT212655 Positive_regulation of Gene_expression of Cort 6 0.39 5.57 4.23 89.68
14 INT168188 Gene_expression of PLXNA2 13 0.58 9 2.73 89.44
15 INT5381 Gene_expression of FYN 18 0.75 7.65 7.35 89.12
16 INT7439 Positive_regulation of CFP 52 0.67 19.97 17.87 88.48
17 INT122953 Gene_expression of COMT 65 0.77 25.84 40.49 85.64
18 INT144739 Regulation of Gene_expression of COMT 11 0.61 3.07 7.08 85.64
19 INT16259 Positive_regulation of Bdnf 336 0.70 183.48 209.82 85.48
20 INT67682 Localization of Bdnf 204 0.81 72.36 88.92 84.00
21 INT48642 Positive_regulation of TCEA1 92 0.70 24.59 53.64 82.56
22 INT3002 Binding of SUGT1 62 0.24 55.9 14.91 75.04
23 INT48567 Transcription of Drd1a 7 0.51 2.44 4.54 74.72
24 INT37215 Positive_regulation of SMN1 18 0.45 8.99 4.87 74.36
25 INT20579 Transcription of Akr1d1 9 0.04 2.91 8.37 73.28
26 INT24989 Positive_regulation of Cfp 125 0.61 29.55 64.9 72.80
27 INT16260 Gene_expression of Bdnf 671 0.78 283.44 339.1 70.00
28 INT16253 Positive_regulation of Gene_expression of Bdnf 196 0.70 92.67 113.01 70.00
29 INT356350 Positive_regulation of Snf8 1 0.02 4.31 4.23 65.80
30 INT190833 Regulation of KCNA1 8 0.53 6.61 4.66 65.40
31 INT17619 Regulation of COMT 12 0.45 8.46 12.22 65.00
32 INT12319 Positive_regulation of Cort 52 0.61 22.55 29.35 63.44
33 INT274527 Regulation of SYNM 3 0.20 2.68 2.7 56.48
34 INT2391 Negative_regulation of PTGS1 501 0.59 207.62 205.6 51.48
35 INT242105 Positive_regulation of Positive_regulation of CFP 5 0.49 1.93 1.32 50.92
36 INT96542 Negative_regulation of SMN1 14 0.51 10.72 3.11 50.72
37 INT330256 Negative_regulation of Binding of SMN1 1 0.11 0.65 1.16 50.72
38 INT7437 Gene_expression of CFP 21 0.65 4.93 3.89 50.52
39 INT37216 Binding of SMN1 11 0.36 6.66 1.86 50.40
40 INT316829 Negative_regulation of SYNM 4 0.54 3.31 3.32 47.52
41 INT11034 Negative_regulation of Akr1d1 23 0.18 3.43 14.84 46.08
42 INT218158 Localization of OAF 2 0.23 0.17 0.62 42.64
43 INT125384 Positive_regulation of Pain1 23 0.49 17.1 14.83 41.36
44 INT198136 Positive_regulation of BCL2A1 7 0.67 5.72 5.05 41.04
45 INT151747 Positive_regulation of PSMD2 26 0.68 17.48 17.89 38.16
46 INT69592 Positive_regulation of PSMD1 27 0.70 17.83 18.98 37.60
47 INT267824 Positive_regulation of Positive_regulation of BCL2A1 3 0.67 1.47 0.96 36.20
48 INT236490 Positive_regulation of SCN11A 2 0.48 0.91 2.37 35.64
49 INT118905 Positive_regulation of Positive_regulation of PAG1 8 0.40 7.55 12.25 25.24
50 INT69742 Positive_regulation of Gene_expression of Hmox2 12 0.69 8.29 8.08 23.60
51 INT108917 Positive_regulation of CRX 23 0.50 21.32 10.5 23.04
52 INT69743 Gene_expression of Hmox2 36 0.78 20.77 14.26 22.96
53 INT76405 Positive_regulation of Hmox2 21 0.43 12.77 8.99 22.40
54 INT12318 Negative_regulation of Positive_regulation of Cort 7 0.43 3.89 2.65 22.00
55 INT81417 Gene_expression of PAG1 94 0.58 90.85 92.79 20.56
56 INT126443 Regulation of ENC1 3 0.23 1.42 2.81 18.16
57 INT63553 Binding of PAG1 14 0.48 12.51 14.76 10.32
58 INT218154 Positive_regulation of Lrncs1 1 0.01 0.59 0.99 8.96
59 INT13333 Regulation of Gene_expression of Drd1a 8 0.36 3.37 4.28 7.52
60 INT13334 Gene_expression of Drd1a 43 0.62 7.73 24.43 6.92
61 INT24569 Negative_regulation of Pain1 26 0.41 21.82 21.08 6.40
62 INT7114 Positive_regulation of Ltp 1192 0.62 290.76 755.77 5.00
63 INT1562 Localization of Crh 499 0.81 126.74 236.68 5.00
64 INT7506 Negative_regulation of Ltp 267 0.46 91.01 176.8 5.00
65 INT7628 Gene_expression of Ltp 273 0.77 70.21 147.87 5.00
66 INT170025 Gene_expression of Fig4 588 0.67 183.27 113.32 5.00
67 INT7627 Negative_regulation of Positive_regulation of Ltp 162 0.50 41.2 106.27 5.00
68 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
69 INT6437 Binding of YY1 154 0.47 26.3 90.46 5.00
70 INT13036 Positive_regulation of Positive_regulation of Ltp 105 0.51 23.71 77.66 5.00
71 INT29708 Gene_expression of Gria1 177 0.78 56.36 77.37 5.00
72 INT117601 Positive_regulation of Trpa1 174 0.70 72.41 71.9 5.00
73 INT171145 Positive_regulation of Fig4 274 0.59 93.55 69.81 5.00
74 INT7344 Gene_expression of TAC1 132 0.75 35.48 68.26 5.00
75 INT21737 Binding of MC1R 129 0.48 45.45 56.54 5.00
76 INT5509 Positive_regulation of Localization of Crh 91 0.70 30.65 53.92 5.00
77 INT19488 Localization of ABAT 56 0.69 21.51 50.56 5.00
78 INT9556 Negative_regulation of NAV1 47 0.59 28.49 49.33 5.00
79 INT170646 Negative_regulation of Fig4 213 0.37 81.29 46.92 5.00
80 INT2783 Gene_expression of Slc3a1 86 0.65 8.84 45.4 5.00
81 INT1564 Localization of OPRM1 41 0.80 8.03 44.67 5.00
82 INT12029 Gene_expression of Car1 143 0.67 29.69 36.39 5.00
83 INT6683 Gene_expression of Drd2 64 0.78 11.31 32.28 5.00
84 INT10797 Binding of CYP2D6 86 0.48 15.09 31.16 5.00
85 INT66868 Positive_regulation of Ceacam3 40 0.69 26.61 28.9 5.00
86 INT5604 Positive_regulation of Drd2 47 0.67 10.75 27.41 5.00
87 INT13995 Gene_expression of gr 96 0.74 48.21 26.54 5.00
88 INT116226 Regulation of NAV1 20 0.51 14.32 25.61 5.00
89 INT58192 Positive_regulation of MRI1 86 0.61 53.81 24.68 5.00
90 INT13145 Positive_regulation of Car1 60 0.70 16.32 23.23 5.00
91 INT5055 Positive_regulation of IFNG 89 0.69 64.03 23.05 5.00
92 INT105021 Binding of GOPC 187 0.40 60.39 20.38 5.00
93 INT12031 Negative_regulation of Car1 44 0.59 20.46 19.36 5.00
94 INT99058 Regulation of PAG1 18 0.45 21.62 18.5 5.00
95 INT150934 Gene_expression of GCH1 17 0.78 14.54 17.53 5.00
96 INT178828 Regulation of Pain1 12 0.14 16.1 15.64 5.00
97 INT52591 Gene_expression of KCNMA1 78 0.76 13.95 15.55 5.00
98 INT22272 Negative_regulation of HTR2A 28 0.57 7.62 13.87 5.00
99 INT132335 Gene_expression of KCNA1 36 0.77 18.31 13.36 5.00
100 INT113490 Gene_expression of SCN9A 22 0.77 5.45 12.27 5.00
101 INT102731 Regulation of ABCB1 29 0.62 5.36 11.67 5.00
102 INT54466 Negative_regulation of Gene_expression of Ltp 19 0.38 5.44 10.91 5.00
103 INT11479 Positive_regulation of KCNMA1 30 0.68 10.07 10.82 5.00
104 INT63773 Gene_expression of DRD2 25 0.78 10.41 10.8 5.00
105 INT139443 Positive_regulation of GCH1 9 0.69 8.2 10.14 5.00
106 INT122952 Positive_regulation of COMT 13 0.50 8.1 8.89 5.00
107 INT148703 Gene_expression of NOVA2 73 0.65 18.05 8.3 5.00
108 INT171146 Negative_regulation of Gene_expression of Fig4 38 0.37 11.41 7.42 5.00
109 INT126314 Positive_regulation of OFC1 25 0.54 7.65 7.39 5.00
110 INT18340 Gene_expression of CRX 16 0.22 13.85 7.13 5.00
111 INT53729 Localization of Cort 14 0.69 6.31 6.97 5.00
112 INT155988 Regulation of Localization of ABAT 5 0.24 2.19 6.59 5.00
113 INT79425 Gene_expression of SMN1 42 0.65 36.37 6.1 5.00
114 INT103880 Positive_regulation of DRD2 9 0.67 5.57 5.93 5.00
115 INT141151 Regulation of PSMD1 16 0.40 8.19 5.86 5.00
116 INT71764 Positive_regulation of Mri1 24 0.44 12.31 5.67 5.00
117 INT166765 Localization of PYCARD 21 0.70 3.89 5.66 5.00
118 INT46152 Positive_regulation of CYP4F22 7 0.46 4.05 5.56 5.00
119 INT113254 Positive_regulation of MFGE8 13 0.09 2.52 5.56 5.00
120 INT129645 Negative_regulation of Gene_expression of TAC1 5 0.42 3.33 5.55 5.00
121 INT97693 Gene_expression of REST 29 0.75 5.51 5.26 5.00
122 INT171019 Gene_expression of SMPD1 26 0.27 12.08 5.08 5.00
123 INT14126 Gene_expression of Grina 13 0.67 4.63 4.57 5.00
124 INT87942 Positive_regulation of LOC500077 12 0.68 3.98 4.55 5.00
125 INT71676 Transcription of DRD2 5 0.69 1.19 4.47 5.00
126 INT6967 Regulation of KCNMA1 28 0.61 3.37 4.3 5.00
127 INT63880 Positive_regulation of FLNA 29 0.59 13.88 3.97 5.00
128 INT30011 Negative_regulation of Sepp1 18 0.54 4.65 3.54 5.00
129 INT46208 Negative_regulation of Scn10a 6 0.58 7.16 3.46 5.00
130 INT46691 Negative_regulation of SCN9A 5 0.50 1.37 3.44 5.00
131 INT12981 Binding of Cort 6 0.48 2.76 3.37 5.00
132 INT69313 Regulation of Scn10a 5 0.60 4.45 3.14 5.00
133 INT100688 Gene_expression of SRC 28 0.75 15.51 3.08 5.00
134 INT118589 Regulation of OFC1 11 0.23 3.35 2.94 5.00
135 INT108501 Binding of ARSD 14 0.32 11.5 2.93 5.00
136 INT150933 Negative_regulation of Positive_regulation of GCH1 3 0.58 1.8 2.77 5.00
137 INT99550 Regulation of FLNA 51 0.54 27.88 2.58 5.00
138 INT242107 Positive_regulation of SYNM 8 0.38 2.82 2.39 5.00
139 INT177598 Regulation of C7orf49 7 0.14 2.23 2.23 5.00
140 INT219682 Gene_expression of CYP4F22 3 0.75 0.97 2.2 5.00
141 INT136572 Localization of Ceacam3 3 0.75 1.83 2.2 5.00
142 INT139403 Positive_regulation of Mcc 3 0.45 1.64 2.11 5.00
143 INT67710 Binding of Sepp1 3 0.41 1.77 1.83 5.00
144 INT150516 Regulation of Tns3 2 0.53 0.55 1.81 5.00
145 INT162139 Positive_regulation of Gene_expression of CRX 2 0.14 1.51 1.71 5.00
146 INT236487 Positive_regulation of Gene_expression of Grina 2 0.08 1.77 1.45 5.00
147 INT179309 Regulation of Gene_expression of KCNMA1 8 0.39 2.36 1.36 5.00
148 INT274526 Localization of SYNM 1 0.33 1.36 1.34 5.00
149 INT225375 Negative_regulation of Cytip 3 0.30 1.63 1.27 5.00
150 INT236488 Regulation of Regulation of Pain1 1 0.01 0.76 1.23 5.00
151 INT236485 Negative_regulation of Regulation of Pain1 1 0.01 0.76 1.23 5.00
152 INT157778 Localization of CYP4F22 2 0.73 0.35 1.15 5.00
153 INT219950 Negative_regulation of Gene_expression of SRC 2 0.29 1.32 1.15 5.00
154 INT34355 Binding of SRMS 7 0.41 3.69 1.06 5.00
155 INT34354 Gene_expression of SRMS 8 0.59 9.62 1.02 5.00
156 INT68788 Localization of CFP 7 0.63 1.07 0.93 5.00
157 INT181326 Binding of TNFAIP1 2 0.29 0.81 0.74 5.00
158 INT225373 Gene_expression of Cytip 7 0.54 0.68 0.67 5.00
159 INT187055 Gene_expression of THAS 4 0.19 2.32 0.61 5.00
160 INT219681 Regulation of CD96 2 0.29 0.13 0.57 5.00
161 INT353378 Regulation of Cytip 1 0.03 0.83 0.46 5.00
162 INT283943 Gene_expression of Lefty1 3 0.12 0.08 0.43 5.00
163 INT185763 Gene_expression of PCSK5 1 0.26 0.17 0.4 5.00
164 INT290820 Positive_regulation of Positive_regulation of CRX 1 0.14 1.09 0.39 5.00
165 INT233917 Gene_expression of MED1 2 0.20 0.17 0.38 5.00
166 INT283945 Positive_regulation of Ptgfrn 1 0.01 0.21 0.22 5.00
167 INT218159 Regulation of SRMS 3 0.39 1.69 0.2 5.00
168 INT353379 Positive_regulation of Nlgn1 1 0.02 0.17 0.17 5.00
169 INT218155 Binding of Lrncs1 1 0.00 0.15 0.16 5.00
170 INT283944 Negative_regulation of Ptgfrn 1 0.01 0.06 0.13 5.00
171 INT283946 Positive_regulation of Lefty1 1 0.03 0.17 0.1 5.00
172 INT308826 Gene_expression of CD96 1 0.43 0 0.1 5.00
173 INT219949 Positive_regulation of TTTY1 1 0.10 0.34 0 5.00
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