P:Paracetamol

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pChart

Pain Term
Category Drug
Synonyms Acetaminophen
Pain Specific Yes
Documents 12669
Hot Single Events 200
Hot Interactions 200

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Paracetamol. They are ordered first by their pain relevance and then by number of times they were reported for Paracetamol. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT349583 Aap Positive_regulation of Gene_expression of Cyp2e1 1 0.18 1.57 3.59 100.00
2 INT349584 Binding of Cyp2e1 and Aap 1 0.10 1.56 3.24 100.00
3 INT69823 Binding of GHR and RYBP 1 0.01 0 3.23 100.00
4 INT91350 Binding of Pla2g4a and RYBP 1 0.00 1.15 2.65 100.00
5 INT349589 Aap Positive_regulation of Cyp2e1 1 0.21 1.84 2.71 100.00
6 INT38161 Binding of Caf and Ack 1 0.21 0.52 2.23 100.00
7 INT153728 RYBP Positive_regulation of Gpt 3 0.03 2.01 2.36 100.00
8 INT349585 Aap Positive_regulation of Etf1 1 0.00 1.68 1.94 100.00
9 INT53751 Positive_regulation of Cyp2e1 Positive_regulation of RYBP 1 0.14 0.89 1.98 100.00
10 INT349588 Aap Positive_regulation of Gene_expression of Ros1 1 0.06 0.73 1.85 100.00
11 INT129212 RYBP Positive_regulation of Tnf 2 0.03 1.9 1.95 100.00
12 INT347396 RYBP Positive_regulation of Binding of Sdcbp 1 0.00 0.92 1.66 100.00
13 INT144280 ACP1 Negative_regulation of Phosphorylation of MAPK1 1 0.37 0.78 1.56 100.00
14 INT347397 RYBP Positive_regulation of Sdcbp 1 0.00 0.22 1.56 100.00
15 INT100784 RYBP Positive_regulation of CYP3A4 1 0.44 0 1.54 100.00
16 INT92369 Binding of CYP2D6 and RYBP 1 0.25 0.15 1.73 100.00
17 INT124099 Binding of GGT5 and RYBP 1 0.00 0.34 1.26 100.00
18 INT124108 Binding of RYBP and Ccne1 1 0.09 0.34 1.26 100.00
19 INT349587 Binding of Aap and Csf2 1 0.04 0.41 1.18 100.00
20 INT69824 Negative_regulation of Binding of GHR and RYBP 1 0.01 0 1.14 100.00
21 INT349586 Aap Regulation of Gene_expression of Ros1 1 0.03 0.56 1.17 100.00
22 INT349590 Aap Positive_regulation of Cytl1 1 0.13 1.31 1.15 100.00
23 INT52076 Binding of RYBP and Abt1 1 0.01 0.28 1.08 100.00
24 INT153727 Sds Negative_regulation of RYBP Positive_regulation of Slc17a5 1 0.02 0.68 1.01 100.00
25 INT136346 Binding of Aap and Ads1 1 0.09 2.95 1.44 100.00
26 INT25112 RYBP Negative_regulation of Binding of PLEKHM1 1 0.01 0 1.17 100.00
27 INT140653 IGF1 Negative_regulation of Protein_catabolism of PARP1 1 0.32 0.63 0.98 100.00
28 INT140652 IGF1 Positive_regulation of Phosphorylation of MAPK1 1 0.26 0.63 0.98 100.00
29 INT153729 RYBP Positive_regulation of Slc17a5 1 0.02 0.65 0.97 100.00
30 INT28186 CYP2E1 Regulation of Positive_regulation of RYBP 1 0.04 0.33 1.08 100.00
31 INT53750 Cyp2e1 Positive_regulation of RYBP 1 0.14 0.44 0.99 100.00
32 INT52806 CYP2E1 Positive_regulation of RYBP 1 0.43 0.24 0.95 100.00
33 INT161511 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il1b 1 0.41 0.27 1.36 100.00
34 INT161513 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Tnf 1 0.33 0.27 1.35 100.00
35 INT144281 ACP1 Negative_regulation of Positive_regulation of MAPK1 1 0.27 0.58 0.94 100.00
36 INT144282 ACP1 Negative_regulation of Positive_regulation of PHOSPHO2 1 0.05 0.58 0.94 100.00
37 INT144284 ACP1 Negative_regulation of PHOSPHO2 1 0.05 0.58 0.93 100.00
38 INT144285 ACP1 Negative_regulation of MAPK1 1 0.37 0.58 0.93 100.00
39 INT98180 Aap Positive_regulation of Positive_regulation of Casp3 1 0.00 1.08 0.97 100.00
40 INT61733 Tlr4 Positive_regulation of Gene_expression of Tnf 3 0.26 1.99 2.36 100.00
41 INT161507 Tlr4 Positive_regulation of Gene_expression of Il1b 1 0.24 0.19 1.25 100.00
42 INT56273 RYBP Negative_regulation of Cyp1a2 1 0.01 0.17 0.9 100.00
43 INT56274 RYBP Negative_regulation of Cyp2e1 1 0.01 0.17 0.9 100.00
44 INT57746 Il1 Regulation of Gene_expression of Ltc4s 1 0.36 0.33 0.88 100.00
45 INT28193 Nppb Positive_regulation of Positive_regulation of RYBP 1 0.29 0.05 0.88 100.00
46 INT28192 Nppb Positive_regulation of CYP2B6 Positive_regulation of Positive_regulation of RYBP 1 0.33 0.05 0.88 100.00
47 INT25113 RYBP Negative_regulation of Binding of PTGER2 1 0.05 0 1.02 100.00
48 INT145181 RYBP Positive_regulation of Gene_expression of Cyp3a62 1 0.02 0.07 0.86 100.00
49 INT120293 RYBP Positive_regulation of Abcc2 1 0.04 0.14 0.86 100.00
50 INT150864 RYBP Positive_regulation of Positive_regulation of Bcl2 1 0.01 0.66 0.86 100.00
51 INT28185 CYP2B6 Positive_regulation of Positive_regulation of RYBP 1 0.29 0 0.82 100.00
52 INT144283 ACP1 Positive_regulation of ABCB1 1 0.63 0.6 0.81 100.00
53 INT56275 RYBP Positive_regulation of Negative_regulation of Cyp1a2 1 0.01 0.17 0.81 100.00
54 INT161508 Tlr4 Positive_regulation of Mapk14 2 0.19 0.46 1.24 100.00
55 INT161509 Tlr4 Positive_regulation of Mapk8 1 0.15 0.3 1.16 100.00
56 INT161510 Tlr4 Positive_regulation of Mapk1 1 0.14 0.3 1.16 100.00
57 INT25110 RYBP Negative_regulation of MTHFS 1 0.02 0 0.92 100.00
58 INT347391 Positive_regulation of RYBP Positive_regulation of Sdcbp 1 0.00 0.22 0.79 100.00
59 INT347398 RYBP Positive_regulation of Positive_regulation of Sdcbp 1 0.00 0.22 0.79 100.00
60 INT144286 ACP1 Negative_regulation of Phosphorylation of PSMC6 1 0.45 0.39 0.78 100.00
61 INT347373 RYBP Positive_regulation of Sdcbp Positive_regulation of Lpo 1 0.00 0 0.78 100.00
62 INT161512 Ppig Negative_regulation of Positive_regulation of S100a8 1 0.02 0.23 1.12 100.00
63 INT347368 RYBP Negative_regulation of GSTK1 1 0.00 0 0.77 100.00
64 INT347394 RYBP Positive_regulation of Lpo 1 0.02 0 0.77 100.00
65 INT49585 Binding of Glul and Selenbp2 1 0.20 0.19 0.76 100.00
66 INT117412 RYBP Negative_regulation of LIG4 1 0.00 0.42 0.76 100.00
67 INT34825 Aap Negative_regulation of Gsr 1 0.01 0.3 0.75 100.00
68 INT51933 MSMB Negative_regulation of Positive_regulation of Gpt 1 0.18 0.33 0.74 100.00
69 INT88500 RYBP Negative_regulation of Positive_regulation of Gtf3a 1 0.00 0.19 0.73 100.00
70 INT167429 Negative_regulation of Mapk8 Negative_regulation of RYBP 1 0.01 1.11 1.09 100.00
71 INT92372 CYP2B6 Positive_regulation of Binding of RYBP 1 0.17 0.09 0.81 100.00
72 INT63588 Aap Positive_regulation of Positive_regulation of Got1 1 0.31 0.6 0.79 100.00
73 INT129216 Negative_regulation of RYBP Positive_regulation of Tnf 1 0.01 1.24 0.98 100.00
74 INT129215 RYBP Positive_regulation of Il10 1 0.01 1.24 0.98 100.00
75 INT129206 RYBP Positive_regulation of Gene_expression of TGFB1 1 0.00 1.04 0.95 100.00
76 INT129214 RYBP Positive_regulation of Gene_expression of Il4 1 0.01 1.04 0.94 100.00
77 INT167355 VEGFA Regulation of RYBP 1 0.01 0.53 0.68 100.00
78 INT129213 RYBP Positive_regulation of Gene_expression of Il10 1 0.01 1.04 0.94 100.00
79 INT129211 RYBP Positive_regulation of Gene_expression of Tnf 1 0.01 1.04 0.94 100.00
80 INT98179 Aap Positive_regulation of Mapk8 1 0.01 0.75 0.74 100.00
81 INT130356 Adcy10 Negative_regulation of Positive_regulation of Crp 1 0.13 0.23 0.71 100.00
82 INT314560 RYBP Positive_regulation of Gene_expression of MYC 1 0.02 0.06 0.67 100.00
83 INT83800 Aap Regulation of Gene_expression of Bcl2l1 1 0.28 0.58 0.64 100.00
84 INT112870 Aap Positive_regulation of Gene_expression of Ccnd1 1 0.24 0.34 0.63 100.00
85 INT347393 RYBP Negative_regulation of Ugcg 1 0.01 0 0.63 100.00
86 INT122475 Binding of Aap and Selenbp1 1 0.01 0.06 0.62 100.00
87 INT28187 CYP2B6 Positive_regulation of RYBP 1 0.31 0.35 0.76 100.00
88 INT120294 RYBP Positive_regulation of Positive_regulation of Abcc2 1 0.02 0.15 0.61 100.00
89 INT803 Aap Regulation of Cyb5 1 0.05 0 0.6 100.00
90 INT802 Aap Regulation of Grhpr 1 0.01 0 0.6 100.00
91 INT112869 Aap Positive_regulation of Gpt 2 0.26 0.75 0.6 100.00
92 INT163376 RYBP Positive_regulation of Gene_expression of Casp3 2 0.01 0.57 0.59 100.00
93 INT102671 Cyp1a2 Regulation of RYBP 1 0.00 0 0.58 100.00
94 INT102666 Cyp2e1 Regulation of Cyp1a2 1 0.20 0 0.58 100.00
95 INT102670 Cyp2e1 Regulation of RYBP 1 0.01 0 0.58 100.00
96 INT804 Aap Negative_regulation of MBD2 1 0.01 0 0.57 100.00
97 INT112700 Aap Positive_regulation of RFFL 1 0.00 0.5 0.57 100.00
98 INT81631 Selenbp2 Negative_regulation of Fas 1 0.03 0.77 0.67 100.00
99 INT81630 Selenbp2 Negative_regulation of Positive_regulation of Fas 1 0.03 0.77 0.67 100.00
100 INT347400 RYBP Regulation of Gene_expression of Ugcg 1 0.01 0 0.57 100.00
101 INT347366 RYBP Regulation of Gene_expression of GSTK1 1 0.00 0 0.57 100.00
102 INT347362 RYBP Regulation of Gene_expression of GSR 1 0.01 0 0.57 100.00
103 INT43515 SEMA6A Negative_regulation of RYBP 1 0.06 0.07 0.54 100.00
104 INT160829 Tyr Regulation of RYBP 1 0.04 0.75 0.53 100.00
105 INT347369 RYBP Positive_regulation of GSR 1 0.01 0.43 0.51 100.00
106 INT347395 RYBP Positive_regulation of Gsr 1 0.01 0.43 0.5 100.00
107 INT56449 Aap Positive_regulation of Icam1 1 0.31 0.75 0.5 100.00
108 INT121944 Nr1i2 Positive_regulation of Gene_expression of Cyp3a11 1 0.78 0.43 0.49 100.00
109 INT347367 RYBP Negative_regulation of GSR 1 0.01 0.09 0.48 100.00
110 INT347364 RYBP Regulation of GSR 1 0.01 0.06 0.48 100.00
111 INT347392 RYBP Regulation of Ugcg 1 0.01 0.06 0.48 100.00
112 INT347365 RYBP Regulation of GSTK1 1 0.01 0.06 0.47 100.00
113 INT135176 Myst2 Regulation of Gene_expression of Hif1a 1 0.24 0.47 0.47 100.00
114 INT76026 Binding of Cyp2e1 and Cyp3a11 1 0.28 0.42 0.64 100.00
115 INT161074 Ccbl1 Negative_regulation of Gsr 1 0.00 0 0.41 100.00
116 INT347399 RYBP Positive_regulation of Ldha 1 0.01 0 0.33 100.00
117 INT138721 Abcc1 Regulation of Gene_expression of Abcc4 1 0.50 0 0.31 100.00
118 INT130561 NCKIPSD Regulation of SERPINF2 1 0.22 0 0.52 100.00
119 INT57964 Myo5a Regulation of Negative_regulation of Cyp1a1 1 0.00 0.1 0.2 100.00
120 INT172895 Binding of Cpox and Selenbp2 1 0.00 0.64 0.2 100.00
121 INT141001 Negative_regulation of CPOX Regulation of Localization of INS 1 0.17 0.07 0.14 100.00
122 INT88881 Negative_regulation of IRF6 Positive_regulation of Nfkb1 1 0.09 0.27 1.03 99.98
123 INT155984 Il1a Negative_regulation of Gene_expression of Cyp3a11 1 0.24 0.92 2.2 99.96
124 INT22920 Negative_regulation of Ccl4 Positive_regulation of Gpt 1 0.00 0.24 0.39 99.96
125 INT100681 Negative_regulation of IL13 Positive_regulation of STAT6 1 0.30 1.39 0.57 99.96
126 INT100683 Negative_regulation of IL4 Positive_regulation of STAT6 1 0.30 0.65 0.27 99.96
127 INT60481 Binding of Ugt1a1 and UGT1A6 1 0.23 0 0.55 99.92
128 INT69011 Binding of Cebpb and Nfkb1 1 0.19 0.75 1.04 99.88
129 INT39971 Ccl4 Positive_regulation of Lpolv 1 0.15 0.32 0.33 99.88
130 INT159755 HP Regulation of OXA1L 1 0.01 0 0.44 99.84
131 INT25109 Negative_regulation of COL7A1 Positive_regulation of PLEKHM1 1 0.01 0 1.16 99.82
132 INT144861 Regulation of Tlr4 Positive_regulation of PGE 1 0.01 0.13 0.17 99.82
133 INT52596 B4GALNT1 Positive_regulation of Gpt 1 0.00 0 0.95 99.80
134 INT139736 Htr1a Positive_regulation of Mapk3 1 0.54 0.13 1.19 99.78
135 INT22921 Ccl4 Positive_regulation of Gpt 1 0.00 0.24 0.39 99.76
136 INT168026 Positive_regulation of HBG2 Regulation of Gpt 1 0.01 0.15 0.89 99.70
137 INT168018 Positive_regulation of Ldha Regulation of Gpt 1 0.01 0.15 0.88 99.70
138 INT100678 IL4 Positive_regulation of STAT6 1 0.49 2.63 1.08 99.68
139 INT100677 IL13 Positive_regulation of STAT6 1 0.36 1.95 0.81 99.68
140 INT288731 Binding of Got1 and Gpt 1 0.23 1.25 1.61 99.66
141 INT288729 Positive_regulation of Binding of Got1 and Gpt 1 0.25 0.61 0.49 99.66
142 INT144862 Tlr4 Positive_regulation of PGE 2 0.13 0.35 0.28 99.62
143 INT28194 Nppb Positive_regulation of CYP2B6 1 0.50 0.05 0.88 99.60
144 INT88875 Ifng Positive_regulation of Transcription of Nos2 1 0.02 0.27 1.03 99.58
145 INT88887 IRF6 Positive_regulation of Transcription of Nos2 1 0.21 0.27 1.02 99.58
146 INT25114 COL7A1 Positive_regulation of PLEKHM1 1 0.01 0 1.15 99.54
147 INT130231 Positive_regulation of Binding of Cat and Sod1 1 0.46 0.3 0.98 99.54
148 INT25111 Binding of PTGDS and PLEKHM1 1 0.01 0 0.97 99.46
149 INT34823 Regulation of Binding of Ldha and Akr7a3 1 0.43 0.28 0.72 99.46
150 INT156749 Gpt Positive_regulation of Gene_expression of Gpt2 1 0.50 0.22 0.1 99.46
151 INT156750 Gpt Positive_regulation of Gpt 1 0.27 0.22 0.1 99.46
152 INT84466 DPP4 Regulation of Localization of Naga 1 0.00 0.87 0.78 99.44
153 INT168025 HBG2 Regulation of Gpt 1 0.01 0.15 0.88 99.40
154 INT168019 Ldha Regulation of Gpt 1 0.01 0.15 0.88 99.40
155 INT168010 Asap1 Positive_regulation of HBG2 1 0.01 3.03 1.82 99.36
156 INT130232 Binding of Cat and Sod1 1 0.35 0.3 0.98 99.34
157 INT167428 Il1b Positive_regulation of Localization of Gpt 1 0.43 1.31 1.11 99.32
158 INT110758 Tnfaip8 Positive_regulation of Positive_regulation of Nos2 1 0.14 0.88 0.34 99.30
159 INT110760 Tnfaip8 Positive_regulation of Positive_regulation of Nfkb1 1 0.14 0.87 0.34 99.30
160 INT110761 Tnfaip8 Positive_regulation of Nos2 1 0.13 0.88 0.34 99.30
161 INT110759 Tnfaip8 Positive_regulation of Nfkb1 1 0.13 0.87 0.34 99.30
162 INT63589 Binding of Got1 and Gpt 1 0.36 0.56 0.74 99.28
163 INT41787 IFNA2 Negative_regulation of Glb1 1 0.04 0.09 0.23 99.28
164 INT156751 Gpt2 Positive_regulation of Gpt 1 0.12 0.21 0.1 99.28
165 INT141041 ZNF404 Negative_regulation of NFATC1 1 0.01 0 0.23 99.26
166 INT155985 Nfkb1 Negative_regulation of Gene_expression of Cyp11a1 1 0.10 0.53 0.95 99.24
167 INT38512 Binding of Cyp2c22 and Atp6v1c2 1 0.00 0.17 0.73 99.24
168 INT112701 Bid Regulation of RFFL 1 0.00 0.52 0.62 99.22
169 INT112699 Bid Regulation of Bax 1 0.25 0.51 0.61 99.22
170 INT349576 Binding of Ugt2b and Sult1a1 1 0.00 0.45 1.03 99.16
171 INT142278 Slc8a1 Regulation of Tnf 1 0.14 0.07 0.89 99.14
172 INT151008 Gpt Positive_regulation of Gene_expression of alp 1 0.08 0.07 0.83 99.12
173 INT349592 GTF2H5 Negative_regulation of Cyp2c22 1 0.00 0.64 0.98 99.04
174 INT61037 Och Positive_regulation of Ptgs1 1 0.00 0 0.95 99.04
175 INT28184 Binding of CYP1A2 and CYP2D6 1 0.00 0 0.7 98.94
176 INT164607 Positive_regulation of GSR Positive_regulation of Gpx1 1 0.01 0.33 0.81 98.88
177 INT77098 Nlrp1a Negative_regulation of Positive_regulation of Ppig 1 0.47 0.68 0.53 98.88
178 INT138426 Abcb1b Regulation of Abcg2 1 0.29 0 0.17 98.84
179 INT34824 Binding of Ldha and Akr7a3 1 0.36 0.28 0.71 98.82
180 INT81295 Ifng Positive_regulation of Gene_expression of Nos2 4 0.39 0.87 2.05 98.74
181 INT88885 IRF6 Positive_regulation of Gene_expression of Nos2 1 0.21 0.1 0.81 98.74
182 INT88878 Negative_regulation of Nfkb1 Positive_regulation of Gene_expression of Nos2 1 0.06 0.1 0.81 98.74
183 INT88883 IRF6 Positive_regulation of Nfkb1 1 0.11 0.53 2.01 98.64
184 INT12327 Igh-Dex Positive_regulation of Plec 1 0.03 0.73 1.57 98.64
185 INT167427 Mapk8 Regulation of Regulation of Tnf 1 0.26 2.83 1.7 98.64
186 INT16014 Ptafr Regulation of Ns5atp9 1 0.32 1.17 0.78 98.56
187 INT75806 Cyp2a5 Negative_regulation of Cyp2g1 1 0.48 0.08 1.09 98.48
188 INT276209 Negative_regulation of Binding of Nos2 and Nfkb1 1 0.14 0.31 0.34 98.42
189 INT158144 Binding of Gpx1 and Glyat 2 0.31 0 1.29 98.26
190 INT276214 Binding of Nos2 and Nfkb1 1 0.12 0.31 0.34 98.24
191 INT288732 Got1 Positive_regulation of Gene_expression of Gpt 1 0.31 0.52 0.23 98.20
192 INT88879 Ifng Positive_regulation of Nfkb1 1 0.01 0.26 1.01 98.16
193 INT276218 Binding of Akt1 and Pten 1 0.26 0.08 0.46 98.12
194 INT74872 Igh-Dex Positive_regulation of Chd7 1 0.01 0.5 0.89 98.08
195 INT138427 Abcc2 Regulation of Abcg2 1 0.30 0 0.17 98.04
196 INT20122 Cyp2c22 Negative_regulation of CYBB 1 0.00 0 0.1 98.00
197 INT39870 Odc1 Negative_regulation of Tk1 1 0.36 0.8 0.46 97.94
198 INT164606 GSR Positive_regulation of Gpx1 1 0.01 0.32 0.8 97.86
199 INT75029 Gstm1 Regulation of Gene_expression of Gstm2 1 0.00 0.1 0.1 97.84
200 INT75032 Gsta2 Regulation of Gene_expression of Gstm2 1 0.00 0.1 0.1 97.84

Single Events

The table below shows the top 200 pain related interactions that have been reported for Paracetamol. They are ordered first by their pain relevance and then by number of times they were reported in Paracetamol. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 100.00
2 INT22967 Positive_regulation of RYBP 94 0.56 37.04 85.92 100.00
3 INT18883 Negative_regulation of RYBP 53 0.56 21.14 57.52 100.00
4 INT4656 Localization of RYBP 49 0.77 5.28 46.21 100.00
5 INT11180 Binding of RYBP 52 0.46 13.86 42.53 100.00
6 INT18774 Gene_expression of RYBP 67 0.65 47.66 37.59 100.00
7 INT17564 Gene_expression of Gpt 322 0.75 208.51 60.36 100.00
8 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58 100.00
9 INT2604 Positive_regulation of Got1 223 0.70 154.78 49.51 100.00
10 INT18884 Regulation of RYBP 25 0.38 11.43 23.2 100.00
11 INT11650 Negative_regulation of Gpt 122 0.59 69.15 30.36 100.00
12 INT47859 Negative_regulation of Cyp2e1 41 0.59 16.92 21.72 100.00
13 INT77435 Positive_regulation of Nos2 343 0.70 208.49 91.43 100.00
14 INT18526 Positive_regulation of Aap 19 0.56 12.28 14.57 100.00
15 INT14111 Positive_regulation of Cyp2c22 41 0.67 7.24 17.88 100.00
16 INT2391 Negative_regulation of PTGS1 501 0.59 207.62 205.6 100.00
17 INT18882 Negative_regulation of Localization of RYBP 11 0.49 1.15 13.51 100.00
18 INT14152 Gene_expression of Slc17a5 46 0.61 20.01 15.9 100.00
19 INT6489 Positive_regulation of Gene_expression of Tnf 140 0.70 92.31 67.85 100.00
20 INT1827 Gene_expression of Aap 11 0.67 9.37 12.66 100.00
21 INT18527 Localization of Aap 31 0.72 5.6 14.42 100.00
22 INT53747 Positive_regulation of Cyp2e1 34 0.70 29.03 13.39 100.00
23 INT11649 Negative_regulation of Positive_regulation of Gpt 25 0.59 13.94 10.87 100.00
24 INT39699 Negative_regulation of Positive_regulation of RYBP 11 0.41 3.73 10.42 100.00
25 INT50058 Negative_regulation of Cpox 907 0.58 426.28 428.29 100.00
26 INT20336 Positive_regulation of CYP2E1 48 0.70 19.26 15.66 100.00
27 INT53746 Regulation of Cyp2e1 11 0.62 3.82 9.52 100.00
28 INT6580 Negative_regulation of Ptgs1 929 0.59 381.53 376.26 100.00
29 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 100.00
30 INT17565 Regulation of Gpt 85 0.60 43.64 13.68 100.00
31 INT49983 Negative_regulation of Aap 12 0.58 3.16 7.92 100.00
32 INT104501 Positive_regulation of Abcc3 19 0.70 1.86 8.62 100.00
33 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85 100.00
34 INT20274 Regulation of Aap 9 0.45 5.55 7.27 100.00
35 INT22214 Positive_regulation of Localization of Gpt 14 0.62 8.42 7.89 100.00
36 INT36560 Binding of Selenbp2 6 0.19 1.42 6.07 100.00
37 INT39746 Binding of Rnf14 2 0.03 1.31 6.03 100.00
38 INT2480 Negative_regulation of Got1 43 0.51 14.47 16.09 100.00
39 INT112459 Localization of Gba 12 0.80 1.45 6.4 100.00
40 INT22919 Negative_regulation of Gpt 18 0.55 6.84 7.4 100.00
41 INT62166 Positive_regulation of Gene_expression of Gpt 64 0.50 39.13 9.69 100.00
42 INT13607 Binding of Ack 11 0.36 5.77 6.01 100.00
43 INT62579 Negative_regulation of Gene_expression of Cyp2e1 8 0.59 2.95 5.48 100.00
44 INT30644 Positive_regulation of Localization of RYBP 6 0.58 0.93 5.43 100.00
45 INT34654 Negative_regulation of Gene_expression of RYBP 7 0.28 2.89 5.31 100.00
46 INT18775 Positive_regulation of Gene_expression of RYBP 7 0.39 3.4 5.08 100.00
47 INT72060 Positive_regulation of Gene_expression of Ros1 127 0.41 76.76 20.91 100.00
48 INT55670 Negative_regulation of Gene_expression of Tnf 83 0.59 57.16 46.33 100.00
49 INT35708 Protein_catabolism of RYBP 7 0.96 0.86 4.86 100.00
50 INT19271 Binding of Aap 6 0.30 0.88 5.27 100.00
51 INT18779 Negative_regulation of Binding of RYBP 5 0.41 1.01 4.74 100.00
52 INT1242 Negative_regulation of Slc17a5 14 0.42 4.06 5.78 100.00
53 INT35735 Positive_regulation of Binding of RYBP 6 0.48 1.38 4.55 100.00
54 INT2040 Positive_regulation of CYP2B6 95 0.69 34.3 25.6 100.00
55 INT49292 Positive_regulation of Cyp1a2 17 0.69 6.16 4.96 100.00
56 INT14700 Regulation of IFNA1 111 0.45 66.16 21.52 100.00
57 INT38160 Binding of Caf 6 0.37 3 5.1 100.00
58 INT83796 Regulation of Gene_expression of Bcl2l1 10 0.61 7.85 4.05 100.00
59 INT53575 Regulation of Gene_expression of Tnf 46 0.62 34.35 20.63 100.00
60 INT28190 Regulation of Positive_regulation of RYBP 3 0.38 1.46 4.47 100.00
61 INT68758 Positive_regulation of Ros1 125 0.46 82.72 25.27 100.00
62 INT4208 Regulation of Got1 23 0.44 6.72 6.62 100.00
63 INT100262 Positive_regulation of Positive_regulation of Cyp2e1 7 0.50 2.39 4.31 100.00
64 INT53749 Positive_regulation of Positive_regulation of RYBP 4 0.09 2.48 3.6 100.00
65 INT16864 Gene_expression of Selenbp2 4 0.76 0.52 3.34 100.00
66 INT45725 Binding of Pdia3 8 0.47 3.61 4.42 100.00
67 INT18872 Negative_regulation of Asap1 18 0.43 8.48 5.42 100.00
68 INT139613 Binding of pr 16 0.47 5.52 8.46 100.00
69 INT36399 Localization of Gs 1 0.05 0.42 3.43 100.00
70 INT145528 Negative_regulation of Gene_expression of Slc17a5 4 0.28 2.47 3.2 100.00
71 INT112 Gene_expression of Pdia3 11 0.74 0.18 3.74 100.00
72 INT12191 Negative_regulation of Localization of Ldha 35 0.59 13.71 12.35 100.00
73 INT78697 Negative_regulation of Gene_expression of Casp3 33 0.57 11.22 16.16 100.00
74 INT71199 Positive_regulation of Gene_expression of Cyp1a2 4 0.69 1.41 3.36 100.00
75 INT112458 Localization of Selenbp2 4 0.04 1.1 4.74 100.00
76 INT85751 Positive_regulation of Positive_regulation of Nos2 40 0.60 23.53 7.72 100.00
77 INT27415 Negative_regulation of Positive_regulation of Got1 15 0.51 10.99 5.14 100.00
78 INT114311 Negative_regulation of Gene_expression of Gpt 33 0.38 17.83 4.94 100.00
79 INT107307 Transcription of IFNA1 30 0.52 18.16 9.61 100.00
80 INT135016 Positive_regulation of Gene_expression of Slc17a5 7 0.55 4.33 3.74 100.00
81 INT26878 Positive_regulation of Localization of Aap 2 0.48 0.48 3.19 100.00
82 INT30645 Regulation of Localization of RYBP 4 0.36 0 3.07 100.00
83 INT135291 Positive_regulation of Positive_regulation of Mapk8 24 0.64 19.37 5.16 100.00
84 INT4403 Binding of CYP2B6 113 0.48 21.17 33.83 100.00
85 INT35908 Positive_regulation of Acap1 3 0.59 0 2.73 100.00
86 INT131123 Gene_expression of Gba 22 0.78 3.74 3.14 100.00
87 INT52084 Localization of Cyp2e1 6 0.71 1.99 2.79 100.00
88 INT122419 Transcription of ABCC1 10 0.70 4.45 4.61 100.00
89 INT68308 Negative_regulation of Positive_regulation of Aap 3 0.24 1.55 2.61 100.00
90 INT131124 Localization of Abcc3 4 0.75 0.48 2.73 100.00
91 INT546 Binding of ALB 311 0.48 85.98 60.14 100.00
92 INT9660 Regulation of TNF 363 0.62 312.94 139.99 100.00
93 INT104493 Negative_regulation of Mapk8 56 0.53 27.76 16.86 100.00
94 INT20462 Binding of ESR1 210 0.44 102.7 26.34 100.00
95 INT48078 Regulation of Gene_expression of Il1b 15 0.62 14.78 9.53 100.00
96 INT71230 Regulation of asa 11 0.55 4.75 5.97 100.00
97 INT64053 Negative_regulation of Positive_regulation of Tmprss11d 3 0.57 1.34 2.38 100.00
98 INT49552 Negative_regulation of Positive_regulation of Casp3 76 0.55 36.04 44.78 100.00
99 INT9853 Negative_regulation of Ugt2b 7 0.54 1.74 2.8 100.00
100 INT108796 Binding of ESR2 5 0.46 6.84 2.36 100.00
101 INT57676 Regulation of Gene_expression of RYBP 2 0.26 0.67 2.34 100.00
102 INT84705 Positive_regulation of Capn2 1 0.05 0.82 2.34 100.00
103 INT60434 Negative_regulation of Positive_regulation of Tnf 20 0.46 10.01 10.64 100.00
104 INT349575 Positive_regulation of Gene_expression of Aap 1 0.15 1.01 2.16 100.00
105 INT96271 Positive_regulation of Gene_expression of Mcpt1 30 0.53 21.34 11.06 100.00
106 INT57677 Regulation of Binding of RYBP 2 0.23 0.53 2.17 100.00
107 INT39900 Positive_regulation of Gene_expression of Ldha 36 0.50 20.35 5.22 100.00
108 INT107091 Regulation of Gene_expression of Cyp2e1 4 0.62 2.17 2.03 100.00
109 INT27991 Positive_regulation of Gene_expression of Selenbp2 1 0.39 0.44 1.91 100.00
110 INT82722 Negative_regulation of Positive_regulation of Cyp2e1 6 0.59 3.74 2.02 100.00
111 INT64648 Regulation of Selenbp2 4 0.23 1.63 2.05 100.00
112 INT95580 Positive_regulation of Afm 5 0.21 5.51 2.04 100.00
113 INT82649 Negative_regulation of Gene_expression of Cyp2e1 3 0.58 2.51 1.93 100.00
114 INT2389 Regulation of PTGS1 86 0.61 31.23 28.95 100.00
115 INT92682 Positive_regulation of Gene_expression of Ctgf 17 0.69 12.16 4.51 100.00
116 INT94406 Regulation of Slc17a5 10 0.44 3.71 3.77 100.00
117 INT54626 Positive_regulation of Protein_catabolism of Ldha 2 0.44 0.55 1.73 100.00
118 INT5307 Regulation of Tnf 87 0.62 78.71 43.4 100.00
119 INT46109 Binding of SERPINF2 6 0.37 1.08 2.06 100.00
120 INT18522 Positive_regulation of Gene_expression of IFNA1 248 0.67 160.85 44.87 100.00
121 INT63671 Negative_regulation of Protein_catabolism of Ldha 1 0.38 0.31 1.68 100.00
122 INT2039 Regulation of CYP2B6 30 0.60 7.75 6.43 100.00
123 INT118394 Positive_regulation of Positive_regulation of Nfe2l2 13 0.70 1.4 2.81 100.00
124 INT151421 Negative_regulation of Positive_regulation of Sdcbp 11 0.30 6.61 3.32 100.00
125 INT115665 Transcription of ABCB1 9 0.71 3.69 1.91 100.00
126 INT39908 Gene_expression of Cyp27b1 16 0.69 4.8 2.83 100.00
127 INT164864 Positive_regulation of Negative_regulation of Mapk8 1 0.31 1.33 1.82 100.00
128 INT128922 Negative_regulation of Gene_expression of Mapk8 6 0.34 3.93 5.36 100.00
129 INT153725 Negative_regulation of Positive_regulation of Slc17a5 5 0.25 2.87 1.68 100.00
130 INT9064 Regulation of Ugt2b 10 0.62 0.61 2.2 100.00
131 INT108585 Positive_regulation of Gene_expression of CASP3 35 0.70 28.37 6.45 100.00
132 INT1850 Binding of OXA1L 77 0.48 7.61 15.22 100.00
133 INT49862 Negative_regulation of Positive_regulation of Gpt 8 0.41 3.49 2.6 100.00
134 INT2135 Regulation of Gpt 13 0.44 2.17 3.03 100.00
135 INT112460 Positive_regulation of Localization of Gba 2 0.06 0.22 1.65 100.00
136 INT8764 Positive_regulation of Positive_regulation of Cyp3a23/3a1 5 0.45 1.62 3.33 100.00
137 INT99409 Positive_regulation of SLC35A2 5 0.67 0.27 2.45 100.00
138 INT97381 Negative_regulation of Positive_regulation of Nos2 34 0.59 16.66 11.6 100.00
139 INT108921 Negative_regulation of Positive_regulation of Mapk9 3 0.25 1.8 1.99 100.00
140 INT131125 Negative_regulation of Localization of Gba 2 0.08 0.24 1.48 100.00
141 INT120234 Positive_regulation of Gene_expression of Cyp3a11 4 0.46 2.21 2.13 100.00
142 INT44288 Binding of Ugt1a1 7 0.45 0.54 1.48 100.00
143 INT67447 Binding of Aldh1l1 1 0.42 0.7 1.48 100.00
144 INT122407 Gene_expression of Abcc4 4 0.70 0.56 1.41 100.00
145 INT122523 Negative_regulation of Negative_regulation of RYBP 1 0.08 0.45 1.32 100.00
146 INT131126 Positive_regulation of Gba 2 0.50 0.65 1.4 100.00
147 INT339 Regulation of Trh 156 0.62 39.27 83.55 100.00
148 INT64804 Positive_regulation of Binding of Aap 1 0.39 0.14 1.34 100.00
149 INT117897 Negative_regulation of Protein_catabolism of CYP3A4 1 0.55 0 1.28 100.00
150 INT62441 Gene_expression of ABCC1 56 0.78 21.01 12.93 100.00
151 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99 100.00
152 INT10833 Regulation of Gene_expression of IL8 68 0.62 38.74 18.46 100.00
153 INT349573 Negative_regulation of Gene_expression of Aap 1 0.12 0.34 1.28 100.00
154 INT38065 Localization of Sfat 3 0.03 1.26 3.71 100.00
155 INT349574 Transcription of Aap 1 0.17 0.45 1.23 100.00
156 INT37863 Regulation of HBG2 11 0.61 3.95 4.34 100.00
157 INT97096 Regulation of Hmox1 18 0.61 6.42 3.9 100.00
158 INT34783 Positive_regulation of Selenbp2 2 0.17 0.35 1.19 100.00
159 INT20332 Positive_regulation of Positive_regulation of CYP1A2 4 0.69 0.68 2.17 100.00
160 INT24983 Binding of MPO 18 0.42 17.56 3.29 100.00
161 INT5594 Regulation of Pdyn 137 0.62 27.04 86.63 100.00
162 INT145273 Transcription of ABCG2 2 0.69 1.72 1.25 100.00
163 INT76864 Negative_regulation of Positive_regulation of Sds 2 0.43 0.62 1.21 100.00
164 INT75802 Regulation of Cyp2g1 2 0.45 0.54 1.12 100.00
165 INT52808 Transcription of RYBP 1 0.40 0.22 1.12 100.00
166 INT91232 Regulation of Positive_regulation of Hmox1 5 0.45 2.43 1.55 100.00
167 INT75505 Regulation of Gene_expression of CDKN1A 24 0.60 12.24 3.07 100.00
168 INT124201 Positive_regulation of Localization of Selenbp2 1 0.02 0 1.1 100.00
169 INT314586 Regulation of Transcription of IFNA1 3 0.04 1.45 1.39 100.00
170 INT9197 Binding of PTGS1 44 0.48 18.48 16.26 100.00
171 INT113606 Positive_regulation of Gene_expression of Mmp9 46 0.64 44 15.07 100.00
172 INT146030 Negative_regulation of Positive_regulation of Ifih1 2 0.29 1.16 1.13 100.00
173 INT55529 Negative_regulation of Gba 13 0.59 7.91 2.1 100.00
174 INT110755 Negative_regulation of Positive_regulation of Mapk8 15 0.46 9.91 2.98 100.00
175 INT61189 Regulation of Positive_regulation of Sord 1 0.18 0.33 1.04 100.00
176 INT349571 Regulation of Positive_regulation of Aap 1 0.13 0.46 1.04 100.00
177 INT38791 Localization of Ack 1 0.59 0.33 1.03 100.00
178 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 100.00
179 INT4643 Negative_regulation of GHR 10 0.45 3.01 2 100.00
180 INT76869 Localization of PAEP 15 0.73 6.57 3.36 100.00
181 INT37981 Negative_regulation of Ack 1 0.37 0.07 1.01 100.00
182 INT97071 Regulation of Gstp1 1 0.43 0.59 1 100.00
183 INT163529 Negative_regulation of Positive_regulation of Mapk8 14 0.43 8.37 3.2 100.00
184 INT56601 Positive_regulation of Ccl4 9 0.47 6.27 3.28 100.00
185 INT129901 Gene_expression of Nr1i2 60 0.73 22.44 6.04 100.00
186 INT95577 Gene_expression of Afm 2 0.20 1.76 0.97 100.00
187 INT101841 Localization of SERPINF2 4 0.68 1.27 1.01 100.00
188 INT19270 Negative_regulation of Binding of Aap 1 0.32 0.07 0.96 100.00
189 INT6405 Gene_expression of Enpep 9 0.67 4.79 3.4 100.00
190 INT55419 Regulation of CYP1A2 19 0.62 5.3 4.75 100.00
191 INT5591 Regulation of Gene_expression of Fos 425 0.62 129.06 265.78 100.00
192 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57 100.00
193 INT14086 Binding of SERPINB1 18 0.34 4.32 3.13 100.00
194 INT7105 Gene_expression of pad 54 0.77 63.68 8.8 100.00
195 INT60205 Transcription of Selenbp2 2 0.71 0.09 0.93 100.00
196 INT52801 Regulation of Gene_expression of Tnf 55 0.62 48.74 26.59 100.00
197 INT6487 Positive_regulation of Positive_regulation of Tnf 21 0.56 16.06 5.64 100.00
198 INT48860 Regulation of Localization of Tnf 25 0.61 20.68 8.78 100.00
199 INT142679 Negative_regulation of Phosphorylation of Mapk9 1 0.17 0.51 1.37 100.00
200 INT44808 Gene_expression of NDUFB5 1 0.65 0.06 1.08 100.00
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