P:Paresthesia

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Pain Term
Category Pain type
Synonyms Paraesthesia
Pain Specific No
Documents 1672
Hot Single Events 102
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Paresthesia. They are ordered first by their pain relevance and then by number of times they were reported for Paresthesia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT321601 Binding of C3 and PRTN3 1 0.00 0.99 0.27 62.40
2 INT321602 Binding of C4A and PRTN3 1 0.00 0.99 0.27 62.40
3 INT16355 GH1 Positive_regulation of IGF1 1 0.24 0.25 0 32.24
4 INT142226 Trpa1 Regulation of Trpv1 2 0.35 0.39 0.44 30.68
5 INT281733 LTK Regulation of IgG 1 0.00 1.37 0.03 12.24
6 INT122780 Ngf Regulation of Gene_expression of Trpv1 4 0.65 3.74 3.11 5.00
7 INT122775 Gdnf Regulation of Gene_expression of Trpv1 4 0.59 2.72 2.42 5.00
8 INT351281 AP1M2 Regulation of NCOR2 1 0.00 0.85 1.9 5.00
9 INT241750 Binding of CD4 and ITIH4 14 0.18 5.72 1.53 5.00
10 INT296950 Tacr1 Negative_regulation of Gene_expression of Cck 1 0.30 0.94 1.11 5.00
11 INT253165 SCN10A Positive_regulation of OVGP1 1 0.06 1.34 0.61 5.00
12 INT314756 IL6 Positive_regulation of Gene_expression of Crp 2 0.13 4.58 0.48 5.00
13 INT353836 Binding of CEACAM7 and ICA1 1 0.08 0.32 0.39 5.00
14 INT289998 CNTF Negative_regulation of Casp3 1 0.04 0.99 0.22 5.00
15 INT289981 Cntf Negative_regulation of Casp3 1 0.02 1.01 0.22 5.00
16 INT289997 CNTF Negative_regulation of Binding of CNTF and Casp3 1 0.05 0.99 0.22 5.00
17 INT289999 Binding of CNTF and Casp3 1 0.04 0.99 0.22 5.00
18 INT273024 Binding of FXYD1 and RLS 1 0.04 1.24 0.21 5.00
19 INT241822 Binding of CD4 and HIVEP1 3 0.01 2.73 0.21 5.00
20 INT259023 CADPS Positive_regulation of Binding of SH2B2 1 0.06 2.05 0.14 5.00
21 INT197712 Binding of HTLVR and ATF7IP 1 0.01 0.55 0.12 5.00
22 INT199595 FGF7 Positive_regulation of Transcription of TNF 1 0.40 0.58 0.11 5.00
23 INT332806 Positive_regulation of Ccl20 Regulation of Map3k8 1 0.05 0.05 0.1 5.00
24 INT276438 Binding of OPN1SW and MYP1 1 0.12 1.21 0.09 5.00
25 INT308225 Alb Positive_regulation of Binding of EIF4G2 1 0.02 0.33 0.09 5.00
26 INT199594 FGF7 Positive_regulation of NFE2L2 1 0.01 0.52 0.09 5.00
27 INT307665 Binding of Mpz and Pmp22 1 0.34 0.39 0.08 5.00
28 INT325295 Binding of SGCA and C14orf166 1 0.04 0.54 0.08 5.00
29 INT199604 Binding of FGF7 and Fgf1 1 0.03 0.21 0.08 5.00
30 INT199603 Positive_regulation of Binding of FGF7 and Fgf1 1 0.04 0.21 0.08 5.00
31 INT307666 Binding of Pmp22 and Gjb1 1 0.31 0.38 0.08 5.00
32 INT307663 Binding of Pmp22 and Egr2 1 0.33 0.39 0.08 5.00
33 INT307664 Binding of Pmp22 and LOC689781 1 0.03 0.39 0.08 5.00
34 INT261262 AIS Negative_regulation of Cyp19a1 1 0.01 0.2 0.08 5.00
35 INT320659 Vsig2 Positive_regulation of Transcription of Nos2 1 0.07 0.65 0.07 5.00
36 INT204246 ETFA Regulation of CD68 1 0.37 1.05 0.04 5.00
37 INT204247 S100B Regulation of CD68 1 0.03 1.05 0.04 5.00
38 INT229098 Binding of TP53 and IER3 1 0.01 1.47 0.03 5.00
39 INT287479 PSMB10 Positive_regulation of TBK1 1 0.00 0.59 0.03 5.00
40 INT287480 Protein_catabolism of NFKBIB Positive_regulation of TBK1 1 0.01 0.6 0.03 5.00
41 INT197713 CNTN2 Positive_regulation of ABCB1 1 0.01 0.34 0 5.00
42 INT239406 Binding of MTTP and TAOK1 1 0.02 0.51 0 5.00
43 INT241793 NBL1 Negative_regulation of B4GALNT1 1 0.00 0.83 0 5.00
44 INT264864 Cd38 Positive_regulation of Localization of INS 1 0.06 0.51 0 5.00
45 INT239407 Binding of MTTP and PADI1 1 0.23 0.5 0 5.00
46 INT336179 Binding of CACNA1F and DLST 1 0.01 1.6 0 5.00
47 INT242102 Nkx2-1 Regulation of Gene_expression of Ttf1 1 0.00 1.55 0 5.00
48 INT239408 Binding of PADI1 and TAOK1 1 0.01 0.51 0 5.00
49 INT300631 Binding of TSC1 and TSC2 1 0.15 2.59 0 5.00
50 INT215978 Binding of HPT and Pth 1 0.01 0.92 0 5.00
51 INT318806 Binding of VEGFA and NCOA1 1 0.00 0.22 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Paresthesia. They are ordered first by their pain relevance and then by number of times they were reported in Paresthesia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT105969 Regulation of SHOX 3 0.20 2.73 1.06 99.84
2 INT2280 Negative_regulation of TNFAIP1 70 0.43 69.43 8.36 99.64
3 INT21900 Gene_expression of Mthfd1 150 0.75 69.47 27.03 99.48
4 INT58904 Localization of TH1L 40 0.68 27.11 10.52 99.36
5 INT5923 Negative_regulation of Rtn4 50 0.36 24.19 27.2 98.88
6 INT72746 Localization of Avpr1a 4 0.73 2.54 0.73 98.60
7 INT3530 Regulation of BCHE 18 0.60 5.47 4.12 98.56
8 INT1497 Negative_regulation of Gh 415 0.59 192.95 74.71 98.52
9 INT56239 Positive_regulation of Rtn4 20 0.26 14.05 18.8 98.44
10 INT720 Positive_regulation of POMC 807 0.70 237.37 353.83 98.16
11 INT39269 Positive_regulation of Negative_regulation of CSF2 3 0.28 1.28 0.88 98.16
12 INT75921 Negative_regulation of Ngfr 13 0.59 8.58 8.35 97.88
13 INT739 Negative_regulation of POMC 358 0.59 102.28 166.77 97.64
14 INT65070 Gene_expression of SHOX 9 0.55 7.72 1.84 97.44
15 INT11554 Negative_regulation of CSF2 129 0.59 108.55 29.44 97.04
16 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 96.92
17 INT3529 Regulation of GOT1 6 0.52 2.4 1.01 96.88
18 INT5793 Binding of CTS 110 0.48 63.91 40.62 96.72
19 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 96.28
20 INT94953 Negative_regulation of Mapk14 156 0.59 104.77 91.51 95.88
21 INT2540 Negative_regulation of Calca 538 0.59 172.11 384.38 95.52
22 INT985 Negative_regulation of GH1 213 0.57 89.53 32.39 95.32
23 INT531 Gene_expression of GH1 376 0.75 193.45 46.24 95.32
24 INT34741 Positive_regulation of Gene_expression of GH1 58 0.67 35.06 7.8 95.32
25 INT264010 Localization of Syncrip 2 0.65 3.06 3.19 95.24
26 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 95.00
27 INT48248 Gene_expression of Scn10a 38 0.78 19.3 25.05 94.76
28 INT99613 Gene_expression of alphaVbeta3 5 0.66 2.53 0.91 94.72
29 INT81578 Gene_expression of TRAP 25 0.72 9.75 2.82 94.72
30 INT65093 Gene_expression of ACP5 8 0.56 2.1 1.02 94.72
31 INT914 Positive_regulation of GH1 292 0.69 100.7 84.91 94.68
32 INT1080 Negative_regulation of Ache 343 0.59 108.51 72.4 94.56
33 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 94.44
34 INT1169 Negative_regulation of Bche 322 0.59 149.22 61.27 94.32
35 INT117675 Transcription of Nav1 46 0.72 30.23 44.01 94.16
36 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69 94.12
37 INT94952 Positive_regulation of Mapk14 305 0.70 197.83 186.61 93.96
38 INT37983 Negative_regulation of PPFIBP1 3 0.57 2.12 1.29 93.56
39 INT97368 Negative_regulation of Nav1 62 0.59 41.56 60.27 93.28
40 INT4554 Negative_regulation of Otor 5 0.35 2.04 3.5 93.24
41 INT1982 Regulation of NARFL 119 0.49 116.2 14.35 93.16
42 INT28872 Positive_regulation of CSRP1 49 0.70 47.23 11.7 92.92
43 INT16358 Positive_regulation of Negative_regulation of NPPA 2 0.41 0.83 0.21 92.08
44 INT50055 Negative_regulation of Rac1 36 0.50 19.74 8.98 91.88
45 INT91647 Gene_expression of PDXK 2 0.49 7.71 2.82 91.64
46 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 91.60
47 INT168370 Gene_expression of NPHS2 1 0.58 0.4 0.26 91.60
48 INT205005 Transcription of SPECC1 3 0.59 1.28 0.14 90.16
49 INT95317 Positive_regulation of Slc6a1 6 0.69 5.91 7.94 90.08
50 INT97367 Gene_expression of Nav1 243 0.78 132.97 286.66 90.08
51 INT117674 Regulation of Gene_expression of Nav1 16 0.62 11.5 22.01 90.08
52 INT73322 Transcription of Scn10a 8 0.69 5.35 4.99 90.00
53 INT16357 Negative_regulation of NPPA 23 0.58 12.37 2.98 89.88
54 INT116717 Gene_expression of CCR7 37 0.76 34.1 7.48 89.52
55 INT4776 Localization of TAC1 82 0.78 16.89 45.21 89.32
56 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08 89.28
57 INT61542 Positive_regulation of Ngfr 15 0.70 6.35 7.34 89.28
58 INT188844 Gene_expression of AES 44 0.58 33.94 5.85 89.24
59 INT36354 Localization of CTs 26 0.64 20.84 9.31 88.84
60 INT22738 Negative_regulation of DYNLL1 17 0.57 6.68 2.06 88.64
61 INT22739 Positive_regulation of DYNLL1 5 0.67 1.69 2.67 88.64
62 INT8159 Binding of ELL 7 0.36 12.62 0.84 88.32
63 INT85260 Negative_regulation of ATF7IP 14 0.41 7.08 3.17 87.28
64 INT154283 Negative_regulation of FAM84B 1 0.07 0.69 0.32 87.08
65 INT163365 Positive_regulation of TNS3 2 0.41 0.96 4.18 87.04
66 INT2569 Gene_expression of Ache 120 0.78 26.29 26.89 86.96
67 INT28151 Positive_regulation of CTs 55 0.61 35.09 20.14 86.88
68 INT19763 Gene_expression of CTs 69 0.78 32.92 18.87 86.88
69 INT296636 Regulation of Otor 1 0.05 0.71 0.24 86.80
70 INT53402 Gene_expression of Htr7 7 0.75 1.13 3.02 86.64
71 INT63536 Gene_expression of Syncrip 7 0.67 7.23 5.44 86.56
72 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52 86.52
73 INT274254 Gene_expression of Mtss1 1 0.06 2.13 0.48 86.48
74 INT274255 Positive_regulation of Gene_expression of Mtss1 1 0.05 0.63 0.42 86.48
75 INT6351 Positive_regulation of Gabbr1 40 0.64 11.99 19 86.28
76 INT16562 Negative_regulation of Positive_regulation of Gabbr1 5 0.43 2.67 3.24 86.28
77 INT2919 Negative_regulation of F8 47 0.59 23.48 5.1 86.24
78 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 86.16
79 INT77855 Gene_expression of Pain1 55 0.75 67.42 54.1 85.92
80 INT101582 Negative_regulation of SNAP25 9 0.57 4.34 2.12 85.80
81 INT4060 Gene_expression of Bche 17 0.70 5.23 6.59 85.72
82 INT201130 Localization of AES 31 0.63 25.45 5.12 85.60
83 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 85.48
84 INT197721 Positive_regulation of ARMC9 36 0.35 20.08 1.03 85.00
85 INT243550 Gene_expression of PSPH 7 0.25 7.49 0.4 84.88
86 INT163962 Regulation of Transcription of Nav1 2 0.35 3.25 2.63 84.88
87 INT242978 Positive_regulation of OVGP1 7 0.28 3.57 1.81 84.12
88 INT1033 Positive_regulation of Ca2 507 0.68 131.76 147.64 83.88
89 INT16150 Positive_regulation of NKG7 10 0.69 10.26 1.73 83.76
90 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84 83.68
91 INT5780 Regulation of Gene_expression of Calca 90 0.62 59.52 85.03 83.68
92 INT4760 Negative_regulation of Gene_expression of Calca 93 0.59 34.19 60.3 83.68
93 INT89714 Regulation of Transcription of Scn10a 3 0.60 2.43 1.9 83.24
94 INT146024 Negative_regulation of Ped 4 0.16 3.06 1.12 83.24
95 INT338108 Regulation of Gene_expression of PSPH 1 0.16 1.2 0.17 82.96
96 INT10847 Gene_expression of LAMC2 39 0.75 27 12.09 82.20
97 INT16996 Gene_expression of PRTN3 113 0.75 85.61 22.57 81.56
98 INT19768 Negative_regulation of LAMC2 11 0.57 10.54 5.32 81.16
99 INT48692 Binding of VEGFA 345 0.48 210.3 21.31 80.92
100 INT5781 Gene_expression of Edn1 190 0.78 99.1 46 80.32
101 INT111477 Gene_expression of KRT7 90 0.74 86.76 4.07 80.08
102 INT112717 Negative_regulation of Binding of VEGFA 21 0.56 11.07 0.99 80.04
103 INT6364 Gene_expression of Edn1 123 0.78 73.76 28.43 79.76
104 INT95652 Gene_expression of Krt20 54 0.61 53.69 3.31 79.76
105 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 79.20
106 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 79.00
107 INT115990 Positive_regulation of Sema3e 1 0.46 1.32 0.2 78.80
108 INT1498 Gene_expression of Gh 521 0.75 220.84 81.16 78.48
109 INT712 Positive_regulation of LDHA 160 0.70 175.25 19.11 78.48
110 INT626 Localization of CALCA 289 0.81 125.39 221.15 78.12
111 INT83198 Positive_regulation of Nos3 78 0.64 35.69 17.71 77.84
112 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 77.48
113 INT285 Positive_regulation of Salpa1 73 0.68 61.47 9.19 77.32
114 INT9782 Binding of HTR1B 43 0.47 12.08 19.83 77.16
115 INT273531 Gene_expression of BRON-J 1 0.31 5.53 0.75 77.00
116 INT168369 Binding of NPHS2 1 0.32 0.58 0.24 77.00
117 INT16359 Positive_regulation of Gene_expression of AGT 30 0.49 28.27 6.14 76.96
118 INT16636 Positive_regulation of Ltb4r 8 0.26 4.48 0.92 76.96
119 INT13085 Positive_regulation of ACE 50 0.70 44.2 8.31 76.64
120 INT12124 Gene_expression of MAPK1 141 0.75 82.4 25.58 75.00
121 INT181642 Negative_regulation of Narf 2 0.01 28.07 4.01 74.96
122 INT105883 Positive_regulation of Phosphorylation of Bcl2 8 0.32 5.67 1.86 74.88
123 INT148291 Positive_regulation of CSF3 9 0.61 6.37 0.7 74.80
124 INT105882 Phosphorylation of Bcl2 11 0.59 8.15 3.73 74.52
125 INT4683 Negative_regulation of PDXK 17 0.55 12.81 4.39 73.68
126 INT10173 Binding of Tnf 45 0.48 35.6 14.32 73.24
127 INT241799 Negative_regulation of CHIT1 13 0.42 4.37 0.44 73.12
128 INT17349 Negative_regulation of Akr1b1 41 0.59 27.03 10.65 72.96
129 INT125242 Localization of RLS 15 0.64 15.87 4.99 72.92
130 INT3161 Regulation of Localization of Gh 163 0.61 35.43 59.45 71.20
131 INT1893 Localization of Gh 1041 0.79 340.23 256.58 70.84
132 INT35584 Binding of ACLY 22 0.35 31.78 7.17 70.72
133 INT3330 Gene_expression of AGT 149 0.76 98.65 22.73 70.64
134 INT105238 Negative_regulation of PRSS3P2 2 0.19 1.26 0.51 70.24
135 INT275807 Gene_expression of Sult2a2 2 0.02 0.38 0.36 69.80
136 INT75546 Transcription of Rtn4 1 0.06 2.87 5.03 69.68
137 INT181405 Gene_expression of Ccl20 26 0.65 23.02 9.46 69.44
138 INT168418 Positive_regulation of RCT 32 0.55 20.2 4.07 69.44
139 INT168783 Positive_regulation of Regulation of Slc6a11 1 0.29 0.94 1.05 69.28
140 INT847 Regulation of Lhb 131 0.61 22.08 46.54 69.20
141 INT26459 Regulation of Prl 14 0.62 7.27 4.92 69.20
142 INT122051 Negative_regulation of ROM1 17 0.48 9.11 3.38 68.84
143 INT95314 Regulation of Slc6a11 3 0.35 0.93 1.22 68.48
144 INT200443 Positive_regulation of AES 27 0.60 22.46 3.22 68.12
145 INT3795 Positive_regulation of Ighm 46 0.68 22.43 6.47 68.00
146 INT1011 Positive_regulation of Ebp 3 0.50 1.59 0.86 67.36
147 INT17739 Gene_expression of S100B 226 0.78 132.7 26.4 66.80
148 INT10214 Gene_expression of VIM 153 0.78 115.88 16.29 65.92
149 INT233007 Negative_regulation of VIM 6 0.41 3.46 0.36 65.92
150 INT2542 Localization of Calca 2008 0.81 518.3 1408.65 65.84
151 INT163963 Negative_regulation of Transcription of Rtn4 1 0.03 0.45 1.06 65.84
152 INT107129 Positive_regulation of RLS 46 0.60 40.1 8.09 65.04
153 INT16449 Binding of IGHG3 67 0.48 39.55 10.59 64.84
154 INT114715 Binding of SRC 8 0.36 4.26 1.32 64.84
155 INT108798 Negative_regulation of Positive_regulation of ALPP 9 0.25 4.26 1.46 64.60
156 INT124643 Binding of DYNLL1 3 0.36 0.9 0.23 64.32
157 INT52021 Regulation of IGHG3 34 0.39 22.43 3.3 63.52
158 INT271327 Gene_expression of PCNT 3 0.62 0.7 0.49 63.20
159 INT68244 Positive_regulation of Ighg1 60 0.61 48.86 5.01 62.52
160 INT141894 Localization of CSF3 9 0.62 5.5 0.64 62.08
161 INT63164 Negative_regulation of Cst7 51 0.50 18.48 20.3 61.96
162 INT242353 Binding of Tcas1 3 0.03 3.31 2.22 61.76
163 INT685 Regulation of AVP 124 0.62 34.9 39.91 61.44
164 INT158017 Binding of PGF 4 0.18 2.92 0.26 60.92
165 INT168784 Regulation of Positive_regulation of Slc6a1 1 0.45 0.87 1.01 60.48
166 INT5398 Positive_regulation of ALPP 178 0.70 110.52 19.18 60.36
167 INT1530 Regulation of Gh 382 0.61 115.96 112.47 60.04
168 INT1735 Gene_expression of HSD11B1 199 0.75 257.87 11.5 59.92
169 INT10841 Positive_regulation of Gene_expression of Gh 101 0.59 45.39 16.96 59.84
170 INT756 Gene_expression of C3 138 0.75 100.6 19.2 59.36
171 INT16997 Binding of PRTN3 34 0.48 33.44 6.45 59.32
172 INT45818 Gene_expression of C4A 35 0.75 26.4 3.52 59.20
173 INT37380 Negative_regulation of Sis 31 0.55 19.89 3.92 58.44
174 INT77281 Negative_regulation of HIVEP1 132 0.49 102.78 5.36 57.80
175 INT53475 Gene_expression of MRI1 116 0.59 77.68 33.98 57.76
176 INT110638 Negative_regulation of COMT 43 0.59 21.03 21.05 56.08
177 INT181587 Negative_regulation of OPN1SW 12 0.51 4.36 0.89 55.68
178 INT170625 Binding of SERPINA5 8 0.32 8.42 0.69 55.68
179 INT3952 Negative_regulation of ALB 116 0.59 72.18 18.35 55.56
180 INT9677 Negative_regulation of Gene_expression of GH1 46 0.48 23.32 3.68 55.04
181 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74 54.80
182 INT95312 Regulation of Slc6a1 3 0.27 0.77 1.09 54.80
183 INT7412 Positive_regulation of SST 71 0.70 24.44 29.48 54.64
184 INT335980 Regulation of Igfals 1 0.17 2.26 0.12 54.64
185 INT73323 Negative_regulation of Scn10a 13 0.58 5.77 7.85 54.60
186 INT7970 Gene_expression of PLOD1 120 0.71 44.42 15.54 54.48
187 INT15604 Gene_expression of FSHB 30 0.56 9.7 2.45 54.16
188 INT1261 Localization of Adh1 63 0.81 19.36 16.09 53.08
189 INT76336 Negative_regulation of PDE5A 192 0.59 112.02 20.09 51.88
190 INT320654 Negative_regulation of Localization of Vsig2 1 0.24 0.75 0.17 51.04
191 INT7147 Localization of Vsig2 7 0.49 4.42 0.86 50.48
192 INT37962 Negative_regulation of REG1A 14 0.43 1.16 4.07 50.00
193 INT128375 Gene_expression of Tcf25 1 0.55 0 0 50.00
194 INT3911 Gene_expression of TNFAIP1 29 0.65 21.68 1.85 49.28
195 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 48.56
196 INT78024 Gene_expression of ACLY 73 0.75 59.15 18.54 48.56
197 INT120154 Gene_expression of SLC9A1 3 0.47 1.3 0.47 47.68
198 INT185181 Phosphorylation of Pth 2 0.64 1.51 0.3 47.68
199 INT58919 Localization of Gap43 10 0.78 3.53 4.61 47.60
200 INT25 Positive_regulation of LAMC2 19 0.67 8.64 7.06 47.52
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