P:Paroxysmal extreme pain disorder

From wiki-pain
Jump to: navigation, search

pChart

Pain Term
Category Disorder
Synonyms None
Pain Specific Yes
Documents 28
Hot Single Events 58
Hot Interactions 2

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Paroxysmal extreme pain disorder. They are ordered first by their pain relevance and then by number of times they were reported for Paroxysmal extreme pain disorder. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT247601 Binding of PEPD and SCN9A 1 0.15 2.26 2.27 100.00
2 INT103332 Ngf Regulation of Gene_expression of TRPV1 3 0.09 2.6 2.4 94.08
3 INT341479 Binding of SCN2A and SCN4A 1 0.37 1.29 0.98 15.84
4 INT341480 Binding of SCN1A and SCN4A 1 0.36 1.29 0.98 15.84
5 INT317184 BMS1 Regulation of Gene_expression of NAV1 1 0.03 1.94 1.62 5.00
6 INT279828 Binding of Scn1a and Scn9a 1 0.39 1.64 0.26 5.00
7 INT279829 Scn1a Regulation of Gene_expression of Scn9a 1 0.42 1.52 0.15 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Paroxysmal extreme pain disorder. They are ordered first by their pain relevance and then by number of times they were reported in Paroxysmal extreme pain disorder. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT46460 Gene_expression of NAV1 288 0.78 135.51 305.75 100.00
2 INT106037 Gene_expression of PEPD 10 0.75 4.18 3.11 100.00
3 INT140401 Binding of PEPD 3 0.47 2.22 2.97 100.00
4 INT5363 Negative_regulation of PEPD 11 0.56 6.49 3.11 100.00
5 INT116226 Regulation of NAV1 20 0.51 14.32 25.61 100.00
6 INT94199 Regulation of DRGX 9 0.07 8.31 10.39 100.00
7 INT36676 Gene_expression of Pepd 2 0.36 1.41 0.82 100.00
8 INT279823 Gene_expression of Pepd 1 0.19 2 1.14 100.00
9 INT106038 Regulation of PEPD 3 0.43 3.93 1.01 100.00
10 INT106039 Negative_regulation of Gene_expression of PEPD 5 0.56 1.37 1.18 100.00
11 INT106036 Negative_regulation of Negative_regulation of PEPD 2 0.42 0.68 0.98 100.00
12 INT275954 Regulation of Lat 4 0.54 0.75 0.37 100.00
13 INT148864 Localization of DRGX 11 0.17 7.67 8.36 99.74
14 INT9556 Negative_regulation of NAV1 47 0.59 28.49 49.33 99.72
15 INT247613 Negative_regulation of Regulation of NAV1 1 0.09 0.78 1.07 99.72
16 INT84162 Negative_regulation of KCNMA1 26 0.58 5.05 7.58 99.44
17 INT129303 Positive_regulation of NAV1 54 0.70 36.92 57.45 99.42
18 INT55224 Gene_expression of DRGX 99 0.31 67.55 67.63 99.24
19 INT111476 Gene_expression of TP63 88 0.76 61.08 11.64 99.24
20 INT247621 Gene_expression of PAMR1 4 0.06 1.49 0.44 99.00
21 INT131413 Positive_regulation of Gene_expression of NAV1 35 0.70 17.5 36.83 98.88
22 INT9381 Positive_regulation of TRPV1 523 0.70 187.4 276.05 98.16
23 INT95167 Positive_regulation of DRGX 33 0.22 26.72 21.04 97.70
24 INT341482 Gene_expression of NMNAT1 1 0.01 3.24 2.79 95.84
25 INT247617 Positive_regulation of PAMR1 1 0.06 2.3 2.07 95.52
26 INT52591 Gene_expression of KCNMA1 78 0.76 13.95 15.55 95.00
27 INT67048 Gene_expression of ITGA4 58 0.75 28.93 10.16 94.48
28 INT94450 Gene_expression of Nav1 359 0.78 131.85 275.46 94.24
29 INT18357 Gene_expression of TRPV1 825 0.78 307.11 382.81 94.08
30 INT11479 Positive_regulation of KCNMA1 30 0.68 10.07 10.82 93.84
31 INT157366 Positive_regulation of Positive_regulation of KCNMA1 2 0.05 2.43 1.74 93.84
32 INT123419 Binding of NAV1 37 0.48 7.09 26.43 92.44
33 INT139350 Binding of SCN1B 2 0.35 1 2.43 91.20
34 INT46692 Binding of SCN9A 4 0.36 2.55 2.13 91.20
35 INT133885 Binding of SCN2A 7 0.47 1.27 1.54 91.20
36 INT139352 Binding of KCNQ2 1 0.33 0.87 0.13 91.20
37 INT139351 Binding of KCNQ3 1 0.33 0.87 0.13 91.20
38 INT52589 Positive_regulation of Gene_expression of SCN5A 14 0.49 3.84 1.33 90.80
39 INT312392 Positive_regulation of Regulation of DRGX 1 0.05 1.51 0.94 90.76
40 INT140399 Regulation of Scn9a 2 0.45 0.74 0.61 90.64
41 INT6782 Gene_expression of SCN5A 156 0.78 33.13 17.88 90.52
42 INT142690 Positive_regulation of Gene_expression of DRGX 10 0.23 8.54 5.69 89.84
43 INT140400 Binding of Scn9a 4 0.36 3.59 2.15 89.44
44 INT11377 Positive_regulation of Ngf 331 0.70 206.5 238 89.28
45 INT49922 Positive_regulation of Positive_regulation of Ngf 21 0.67 14.46 17.68 89.28
46 INT247614 Positive_regulation of Gene_expression of PAMR1 1 0.05 0.19 0.09 87.84
47 INT285167 Binding of PSMC4 2 0.04 0.56 0.72 86.16
48 INT6967 Regulation of KCNMA1 28 0.61 3.37 4.3 85.20
49 INT247615 Binding of URI1 2 0.20 1.17 1.13 84.72
50 INT85767 Gene_expression of Scn9a 11 0.76 9.27 2.74 84.44
51 INT139546 Gene_expression of URI1 3 0.75 3 1.49 84.00
52 INT55223 Regulation of Gene_expression of DRGX 6 0.09 3.77 5.15 82.40
53 INT5680 Gene_expression of Ngf 530 0.78 264.29 310.56 82.28
54 INT16254 Positive_regulation of Gene_expression of Ngf 144 0.70 80.61 82.08 82.28
55 INT252999 Gene_expression of TAF9 12 0.75 12.65 2.92 81.68
56 INT262317 Binding of TAF9 7 0.31 9.67 2.15 81.68
57 INT247619 Regulation of Positive_regulation of DRGX 1 0.03 1 0.97 81.04
58 INT193823 Positive_regulation of Gene_expression of TP63 7 0.18 7.74 1.57 80.32
59 INT60161 Gene_expression of EPHA3 43 0.75 3.66 6.25 79.60
60 INT168312 Positive_regulation of Gene_expression of EPHA3 8 0.49 0.97 1.32 79.60
61 INT152352 Negative_regulation of Localization of DRGX 2 0.07 0.87 2.14 72.80
62 INT319920 Negative_regulation of Localization of SCN9A 1 0.29 0.31 0.92 72.80
63 INT279818 Gene_expression of Gm4425 1 0.01 0.77 0.47 72.56
64 INT319919 Localization of SCN9A 1 0.51 0.31 0.92 72.16
65 INT149518 Regulation of Gene_expression of NAV1 7 0.62 6.73 9.62 70.12
66 INT279817 Regulation of Gm4425 1 0.00 1.18 0.45 69.20
67 INT306741 Positive_regulation of Positive_regulation of TP63 2 0.05 1.16 0.49 67.04
68 INT113985 Positive_regulation of TP63 9 0.50 8.79 1.62 66.68
69 INT252968 Positive_regulation of TAF9 11 0.45 5.28 3.68 64.04
70 INT113490 Gene_expression of SCN9A 22 0.77 5.45 12.27 60.64
71 INT4449 Positive_regulation of NA 179 0.55 40.26 37.82 55.48
72 INT341483 Positive_regulation of NMNAT1 1 0.01 0.6 0.76 53.52
73 INT202527 Negative_regulation of Gene_expression of DRGX 5 0.07 1.53 2.54 50.00
74 INT278538 Negative_regulation of Negative_regulation of NAV1 2 0.42 0.84 1.56 49.08
75 INT123420 Negative_regulation of Gene_expression of KCNMA1 7 0.58 0.25 0.33 43.40
76 INT6623 Gene_expression of NA 231 0.78 45.78 59.36 37.76
77 INT341481 Binding of SCN8A 1 0.28 1.47 1.23 30.00
78 INT93308 Gene_expression of PIRT 13 0.09 2 2.92 20.32
79 INT23598 Binding of SCN5A 32 0.40 16 5.35 19.76
80 INT65832 Positive_regulation of PIRT 4 0.07 0.83 1.42 18.08
81 INT103518 Negative_regulation of SCN2A 17 0.57 8.4 5.4 10.56
82 INT341484 Negative_regulation of SCN1A 1 0.53 1.27 0.94 9.76
83 INT9382 Regulation of TRPV1 149 0.62 53.99 77.46 5.00
84 INT116321 Regulation of Nav1 38 0.62 26.62 37.97 5.00
85 INT14031 Gene_expression of Npy 107 0.78 36.48 35.4 5.00
86 INT103262 Localization of Nav1 53 0.81 19.23 34.44 5.00
87 INT114507 Negative_regulation of Gene_expression of NAV1 17 0.43 7.24 15.93 5.00
88 INT21794 Positive_regulation of Gene_expression of Npy 20 0.70 8.44 9.3 5.00
89 INT61495 Positive_regulation of ICA1 8 0.49 4.19 3.87 5.00
90 INT12844 Binding of TP63 15 0.47 10.57 3.38 5.00
91 INT317186 Regulation of BMS1 1 0.04 3.9 3.17 5.00
92 INT70738 Negative_regulation of Gabrg2 7 0.57 4 2.96 5.00
93 INT98376 Gene_expression of tk 27 0.51 21.9 2.23 5.00
94 INT317185 Positive_regulation of Positive_regulation of NAV1 1 0.47 1.51 2.08 5.00
95 INT157927 Gene_expression of Scn1a 5 0.64 6.55 2.02 5.00
96 INT279822 Gene_expression of Scn2a1 2 0.65 1.73 1.85 5.00
97 INT163157 Binding of BMS1 3 0.42 3.6 1.77 5.00
98 INT168681 Gene_expression of BMS1 5 0.37 2.7 1.62 5.00
99 INT130332 Gene_expression of Adam17 14 0.50 4.84 1.56 5.00
100 INT317187 Positive_regulation of BMS1 1 0.04 0.98 1.48 5.00
101 INT153599 Gene_expression of SCN1A 8 0.75 7.01 1.47 5.00
102 INT35742 Positive_regulation of tk 8 0.43 5.53 1.33 5.00
103 INT236437 Negative_regulation of ARHGAP8 1 0.04 0.88 1.07 5.00
104 INT115481 Gene_expression of CDSN 6 0.10 2.53 1.03 5.00
105 INT236439 Gene_expression of ARHGAP8 1 0.06 0.62 0.88 5.00
106 INT279821 Regulation of Scn9a 2 0.44 2.79 0.83 5.00
107 INT44293 Regulation of TP63 6 0.24 2.88 0.76 5.00
108 INT236438 Regulation of ARHGAP8 1 0.02 0.42 0.57 5.00
109 INT236441 Localization of ARHGAP8 1 0.06 0.57 0.55 5.00
110 INT236440 Binding of ARHGAP8 1 0.03 0.31 0.38 5.00
111 INT199566 Positive_regulation of Gene_expression of tk 4 0.39 3.06 0.31 5.00
112 INT226598 Localization of PSMC1 1 0.21 0.33 0.22 5.00
113 INT259867 Binding of SCN1A 2 0.36 4.7 0.21 5.00
114 INT226597 Regulation of Localization of DRGX 1 0.08 0.32 0.21 5.00
115 INT74485 Positive_regulation of Scn9a 2 0.49 0.81 0.19 5.00
116 INT226596 Localization of DIS3L 1 0.05 0.26 0.12 5.00
117 INT279825 Negative_regulation of Scn9a 1 0.37 0.8 0.08 5.00
118 INT279814 Gene_expression of Scn3a 1 0.50 1.63 0.05 5.00
119 INT279826 Negative_regulation of Scn1b 1 0.35 1.31 0.04 5.00
120 INT279820 Negative_regulation of Scn2a1 1 0.35 1.31 0.04 5.00
121 INT279816 Negative_regulation of Scn1a 1 0.40 1.31 0.04 5.00
122 INT279815 Positive_regulation of Gene_expression of Scn9a 1 0.43 0.67 0.03 5.00
123 INT260734 Gene_expression of Acin1 2 0.16 1 0.03 5.00
124 INT279819 Positive_regulation of Gene_expression of Acin1 1 0.12 0.67 0.03 5.00
125 INT279824 Positive_regulation of Scn1a 1 0.47 1.22 0 5.00
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox