P:Regional anesthesia

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Pain Term
Category Treatment
Synonyms None
Pain Specific Yes
Documents 2930
Hot Single Events 71
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Regional anesthesia. They are ordered first by their pain relevance and then by number of times they were reported for Regional anesthesia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT353836 Binding of CEACAM7 and ICA1 1 0.08 0.32 0.39 94.48
2 INT48381 CSF2 Positive_regulation of ITGAM 2 0.30 0.38 0.95 71.20
3 INT164636 Negative_regulation of CSF2 Positive_regulation of ITGAM 1 0.26 0.14 0.25 71.20
4 INT12390 AVP Regulation of Localization of POMC 1 0.29 0.27 0.3 64.96
5 INT87555 TPSAB1 Positive_regulation of IGHE 1 0.42 0.71 0.43 61.28
6 INT87556 TPSAB1 Positive_regulation of CD79A 1 0.40 0.7 0.42 59.56
7 INT256897 IGKV1D-39 Regulation of BAG3 1 0.04 1.77 0.94 26.60
8 INT48385 CSF2 Regulation of Gene_expression of ITGAM 2 0.16 0.29 0.68 25.00
9 INT164635 CSF2 Regulation of Gene_expression of ROS1 1 0.15 0.09 0.24 25.00
10 INT351281 AP1M2 Regulation of NCOR2 1 0.00 0.85 1.9 5.00
11 INT207783 Binding of MRC1 and Ap3d1 1 0.00 2.54 0.22 5.00
12 INT207784 Ap3d1 Regulation of CACNA1S 1 0.05 0.97 0.16 5.00
13 INT207785 Binding of RYR1 and Ap3d1 1 0.06 3.24 0.13 5.00
14 INT207776 Binding of FKBP1A and RYR1 1 0.05 0.59 0.12 5.00
15 INT254643 Binding of Mapk8ip1 and Slc9a3r2 1 0.00 0.27 0.12 5.00
16 INT205537 ATP8A2 Negative_regulation of Negative_regulation of RHOXF2 1 0.01 0 0.07 5.00
17 INT345966 Binding of Arid1a and al44 1 0.00 1.56 0.05 5.00
18 INT345965 Binding of Lep and al44 1 0.01 1.43 0.05 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Regional anesthesia. They are ordered first by their pain relevance and then by number of times they were reported in Regional anesthesia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT462 Regulation of Pomc 157 0.62 41.67 67.27 100.00
2 INT36779 Localization of HBG2 3 0.59 1.57 2 100.00
3 INT28583 Positive_regulation of Gene_expression of Atp7b 4 0.06 0.34 3.24 100.00
4 INT28582 Positive_regulation of Positive_regulation of Atp7b 1 0.04 0.1 1 100.00
5 INT671 Positive_regulation of Cea 221 0.69 164.5 47.79 99.96
6 INT17182 Binding of Cea 25 0.48 14.98 4.16 99.96
7 INT927 Gene_expression of Oxt 184 0.78 44.71 35.79 99.96
8 INT684 Binding of AVP 38 0.48 13.9 8.85 99.90
9 INT695 Binding of POMC 304 0.48 56.66 126.85 99.90
10 INT30372 Regulation of ADRB3 8 0.60 0.57 2.24 99.82
11 INT11897 Gene_expression of Atp7b 25 0.13 7.85 12.5 99.68
12 INT720 Positive_regulation of POMC 807 0.70 237.37 353.83 99.58
13 INT683 Positive_regulation of AVP 173 0.70 74.55 46.41 99.58
14 INT1921 Gene_expression of CEACAM7 47 0.78 43.23 2.53 99.56
15 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52 99.52
16 INT36453 Binding of ABCA1 48 0.45 19.9 10.84 99.30
17 INT110609 Binding of KCNK2 3 0.48 0.25 2.88 99.20
18 INT94952 Positive_regulation of Mapk14 305 0.70 197.83 186.61 98.72
19 INT140288 Localization of Pon1 4 0.78 6.15 1.15 98.24
20 INT21938 Positive_regulation of Atp7b 26 0.10 11.33 7.1 97.96
21 INT6625 Negative_regulation of Pth 96 0.58 57.6 8.24 97.68
22 INT18010 Positive_regulation of CD40LG 122 0.70 100.8 18.46 97.64
23 INT203 Positive_regulation of Pomc 257 0.70 90.56 92.84 97.24
24 INT2021 Binding of HBG2 13 0.36 4.2 2.65 96.32
25 INT158123 Negative_regulation of Gene_expression of COL5A2 19 0.46 15.27 2.23 96.28
26 INT25493 Gene_expression of TFPI 74 0.76 39.44 14.78 95.64
27 INT79149 Gene_expression of CSE 26 0.58 11.76 14.16 95.64
28 INT6884 Negative_regulation of pr 20 0.42 13.18 7.97 95.36
29 INT79894 Gene_expression of Sae1 2 0.11 1.65 0.54 95.36
30 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 95.28
31 INT69436 Negative_regulation of Gene_expression of ROS1 81 0.38 46.58 12.22 95.28
32 INT158124 Gene_expression of COL5A2 136 0.69 72.3 12.44 95.00
33 INT110608 Negative_regulation of KCNK2 10 0.59 0.91 3.26 94.80
34 INT10915 Gene_expression of ITGAM 164 0.78 92.42 29.78 93.52
35 INT53684 Negative_regulation of Gene_expression of ITGAM 23 0.59 14.36 5.66 93.52
36 INT886 Gene_expression of Pomc 676 0.78 129.87 295.98 93.20
37 INT5506 Positive_regulation of Gene_expression of Pomc 132 0.70 26.78 54.3 93.20
38 INT207778 Positive_regulation of Binding of Ap3d1 1 0.06 1.26 0.52 93.20
39 INT2782 Regulation of Gene_expression of Pomc 75 0.62 15.04 38.97 92.92
40 INT110153 Regulation of Gene_expression of Mc2r 1 0.04 0.18 0.49 92.92
41 INT6273 Gene_expression of Mc2r 7 0.18 1.04 1.38 92.64
42 INT207777 Binding of Ap3d1 1 0.07 14.51 1.91 92.24
43 INT110605 Gene_expression of KCNK2 24 0.78 5.71 6.85 91.84
44 INT94953 Negative_regulation of Mapk14 156 0.59 104.77 91.51 91.44
45 INT298 Negative_regulation of ADRB3 23 0.59 6.82 7.56 90.64
46 INT178037 Gene_expression of Del(7)Tyr<c-23DVT>-p 18 0.22 23.44 4.07 90.64
47 INT937 Positive_regulation of Oxt 195 0.70 37.82 49.3 89.56
48 INT34864 Binding of Cp 23 0.47 5.17 1.78 89.12
49 INT3400 Positive_regulation of pr 57 0.68 36.9 16.24 88.80
50 INT183467 Negative_regulation of TBK1 6 0.12 9.89 5.41 88.56
51 INT34739 Positive_regulation of Del(7)Tyr<c-23DVT>-p 17 0.35 18.86 2.54 86.88
52 INT64806 Binding of asa 10 0.30 4.11 3.14 86.16
53 INT29809 Gene_expression of Tspo 8 0.75 4.12 4.54 85.88
54 INT36716 Positive_regulation of Gene_expression of Tspo 4 0.68 3.48 3.49 85.88
55 INT163859 Negative_regulation of Gene_expression of Tspo 1 0.41 0.17 0.64 85.88
56 INT155983 Gene_expression of Cyp11a1 7 0.58 2.6 3.38 85.68
57 INT163861 Positive_regulation of Gene_expression of Cyp11a1 2 0.38 0.64 1.53 85.68
58 INT163853 Negative_regulation of Gene_expression of Cyp11a1 1 0.32 0.17 0.64 85.68
59 INT163852 Gene_expression of Hsd3b1 1 0.75 0.45 1.36 85.32
60 INT163851 Negative_regulation of Gene_expression of Hsd3b1 1 0.41 0.17 0.64 85.32
61 INT163850 Positive_regulation of Gene_expression of Hsd3b1 1 0.49 0.17 0.61 85.32
62 INT163857 Gene_expression of Dlc1 1 0.03 0.17 0.6 84.76
63 INT339034 Negative_regulation of Slc25a20 1 0.09 0.44 0.28 84.56
64 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 83.92
65 INT6133 Negative_regulation of Serpinc1 56 0.58 42.8 8.35 83.76
66 INT118254 Negative_regulation of Ppcs 4 0.39 2.49 0.79 83.68
67 INT299845 Positive_regulation of TMEM200B 1 0.40 3.45 0.47 82.96
68 INT27346 Regulation of ANIB1 5 0.03 3.47 1.47 82.52
69 INT66750 Positive_regulation of MS 1 0.41 0.1 0.13 81.76
70 INT134811 Gene_expression of ICA1 22 0.44 6.47 2.42 81.00
71 INT35349 Gene_expression of CENPJ 52 0.57 25.36 2.54 80.76
72 INT738 Regulation of POMC 459 0.62 111.19 243.74 79.96
73 INT685 Regulation of AVP 124 0.62 34.9 39.91 79.96
74 INT345964 Regulation of Arid1a 1 0.11 0.95 0.19 79.92
75 INT61784 Positive_regulation of CENPJ 27 0.51 11.46 2.28 79.68
76 INT2947 Regulation of TFPI 10 0.44 5.81 4.86 79.36
77 INT79148 Regulation of CSE 1 0.14 0.19 1.74 79.36
78 INT44637 Positive_regulation of Slc9a3r2 18 0.55 7.27 1.72 78.16
79 INT253 Regulation of PRL 184 0.62 47.27 65.79 77.32
80 INT3607 Gene_expression of Cbr1 4 0.59 1.17 1.48 76.68
81 INT27345 Positive_regulation of ANIB1 9 0.07 9.81 3.46 76.64
82 INT120220 Gene_expression of ANIB1 4 0.65 1.82 1.92 76.64
83 INT825 Negative_regulation of ADRA1D 54 0.58 20.25 22.78 75.72
84 INT169479 Negative_regulation of Rcan1 1 0.23 0.62 0.29 75.64
85 INT8385 Gene_expression of F13a1 8 0.76 2.23 1.39 75.12
86 INT16644 Positive_regulation of Plg 16 0.60 6.38 3.62 75.00
87 INT11335 Regulation of Ptger2 46 0.51 22.3 15.42 75.00
88 INT16870 Negative_regulation of Gsr 27 0.59 10.28 11.81 75.00
89 INT16871 Negative_regulation of Positive_regulation of Gsr 1 0.58 0 0.23 75.00
90 INT3842 Positive_regulation of Gsr 14 0.69 3.48 3.55 75.00
91 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 75.00
92 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 75.00
93 INT3950 Gene_expression of Ptger2 293 0.77 122.28 62.42 75.00
94 INT719 Negative_regulation of SGCG 96 0.57 47.91 30.22 75.00
95 INT17739 Gene_expression of S100B 226 0.78 132.7 26.4 75.00
96 INT11893 Positive_regulation of Ptger2 96 0.69 31.49 21.92 75.00
97 INT35029 Positive_regulation of Gene_expression of Ptger2 66 0.43 26.37 13.99 75.00
98 INT9899 Gene_expression of Vwf 91 0.74 45.06 9.13 75.00
99 INT10889 Gene_expression of F8 60 0.78 41.36 5.06 75.00
100 INT23775 Regulation of S100B 24 0.62 16.75 2.57 75.00
101 INT56817 Regulation of Eno2 16 0.61 10.64 1.99 75.00
102 INT51064 Regulation of Gene_expression of S100B 13 0.60 5.02 1.34 75.00
103 INT109880 Negative_regulation of Gene_expression of F8 3 0.12 2.12 0.54 75.00
104 INT150040 Negative_regulation of Gene_expression of Vwf 4 0.30 1.43 0.45 75.00
105 INT44758 Gene_expression of PILRB 1 0.04 0 0.24 75.00
106 INT198613 Localization of ELOVL1 2 0.56 1.84 0.52 74.36
107 INT184747 Regulation of Skap2 2 0.26 1.34 0.31 72.56
108 INT17489 Regulation of F13A1 28 0.45 15.79 4.93 71.88
109 INT92877 Gene_expression of PDE5A 35 0.76 17.1 2.7 70.56
110 INT163858 Regulation of Gene_expression of Cyp11a1 1 0.46 0.55 1.53 70.48
111 INT125226 Binding of Nf2 7 0.48 5.94 2.02 70.40
112 INT163860 Regulation of Gene_expression of Hsd3b1 1 0.44 0.28 0.76 70.20
113 INT44578 Binding of Hbb 19 0.48 3.12 4.2 69.76
114 INT328080 Localization of Ppcs 1 0.40 1.23 0.31 69.68
115 INT34870 Positive_regulation of OPA1 18 0.59 10.66 5 68.40
116 INT5454 Localization of CRH 124 0.79 79.18 41.53 68.00
117 INT53964 Negative_regulation of Prkaca 131 0.58 38.76 69.52 67.80
118 INT130372 Transcription of PDE5A 7 0.72 1.93 0.4 67.28
119 INT64158 Negative_regulation of Prkca 121 0.59 29.8 88.66 66.60
120 INT136652 Regulation of TFP1 1 0.23 0.16 1.36 66.40
121 INT127849 Binding of LOC246267 1 0.19 0.94 0.17 66.24
122 INT214 Localization of AVP 370 0.81 208.51 91.09 64.96
123 INT20488 Negative_regulation of TFP1 2 0.22 0.07 0.99 64.88
124 INT19483 Positive_regulation of Ppcs 3 0.37 14.1 1.36 64.64
125 INT50970 Positive_regulation of Ntrk1 51 0.57 29.38 22.83 64.32
126 INT443 Localization of POMC 1020 0.81 284.52 443.17 64.16
127 INT3602 Negative_regulation of Shbg 148 0.53 69.05 11.65 62.28
128 INT8684 Positive_regulation of ANGPTL5 45 0.69 36.29 7.47 61.92
129 INT8683 Positive_regulation of F3 31 0.67 42.89 6.21 61.92
130 INT11710 Positive_regulation of SERPINC1 6 0.59 6.15 1.47 61.92
131 INT136651 Binding of Calm2 30 0.42 1.09 3.11 61.44
132 INT159 Negative_regulation of Localization of Prl 416 0.59 55.34 171.8 61.36
133 INT157 Positive_regulation of Localization of Prl 790 0.70 104.54 374.78 59.36
134 INT6128 Positive_regulation of Localization of POMC 256 0.70 68.77 121.64 59.36
135 INT345951 Negative_regulation of Arid1a 1 0.10 6.11 0.33 58.36
136 INT68216 Binding of NF1 40 0.48 51.24 4.59 58.32
137 INT61837 Regulation of Regulation of ADRB3 1 0.26 0.06 0.24 56.32
138 INT74563 Positive_regulation of Gene_expression of ROS1 258 0.61 168.18 34.08 56.08
139 INT77619 Gene_expression of Prkaca 43 0.75 8.55 14.13 55.96
140 INT64159 Gene_expression of Prkca 90 0.78 34.65 55.97 55.64
141 INT158 Localization of Prl 2431 0.81 378.96 952.2 55.28
142 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56 55.20
143 INT130599 Negative_regulation of PAICS 4 0.30 2.33 0.7 53.76
144 INT205541 Regulation of RHOXF2 1 0.06 0.2 0.21 53.28
145 INT23589 Positive_regulation of CALCR 9 0.67 6.73 1.25 50.24
146 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 50.00
147 INT3546 Binding of Oxt 54 0.48 9.75 10.81 50.00
148 INT64346 Positive_regulation of S100B 95 0.70 63.11 9.17 50.00
149 INT36135 Negative_regulation of CSE 19 0.50 1.77 7.81 50.00
150 INT131929 Positive_regulation of Gene_expression of S100B 25 0.67 12.61 2.83 50.00
151 INT4435 Gene_expression of PIK3C2A 20 0.77 14.43 2.48 50.00
152 INT7743 Binding of Hrh2 19 0.47 7.75 7.11 49.04
153 INT70970 Binding of COPD 144 0.42 180.34 18.29 46.80
154 INT55259 Negative_regulation of Calm2 9 0.49 1.87 3.4 45.44
155 INT136654 Positive_regulation of Regulation of TFP1 1 0.21 0.09 0.58 44.00
156 INT20922 Positive_regulation of Localization of CRH 18 0.67 11.12 6.79 43.04
157 INT57057 Gene_expression of APC 131 0.78 122.24 8.7 42.88
158 INT5455 Negative_regulation of Localization of CRH 16 0.49 7.31 6.41 41.92
159 INT102036 Positive_regulation of Dre 12 0.59 4.41 2.4 41.84
160 INT13370 Negative_regulation of Scn4a 11 0.57 4.05 5.47 41.04
161 INT15918 Gene_expression of Serpine1 60 0.62 41.73 7.72 40.88
162 INT121085 Negative_regulation of GPHA2 3 0.22 1.99 1.56 40.88
163 INT97368 Negative_regulation of Nav1 62 0.59 41.56 60.27 40.60
164 INT390 Positive_regulation of Agt 170 0.70 61.47 36.08 38.80
165 INT56364 Regulation of Gene_expression of ITGAM 19 0.61 9.82 5.09 33.12
166 INT211112 Positive_regulation of Etn1 3 0.28 4.28 0.92 31.92
167 INT189913 Positive_regulation of Arid1a 4 0.44 1.82 0.26 31.44
168 INT32517 Positive_regulation of LRPAP1 13 0.49 7.4 3.44 30.72
169 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 25.00
170 INT69441 Regulation of Gene_expression of ROS1 38 0.50 26.78 6.78 25.00
171 INT59454 Regulation of Gene_expression of CSF2 22 0.52 19.67 2.69 25.00
172 INT110610 Regulation of KCNK2 4 0.60 0.81 1.42 25.00
173 INT136650 Gene_expression of Calm2 18 0.51 1.57 1.39 25.00
174 INT136653 Gene_expression of TFP1 1 0.39 0.29 1.35 25.00
175 INT110607 Regulation of Gene_expression of KCNK2 4 0.45 0.59 0.64 25.00
176 INT110611 Gene_expression of KCNK10 2 0.39 0.2 0.37 25.00
177 INT110606 Regulation of KCNK10 1 0.11 0.06 0 25.00
178 INT345952 Positive_regulation of Gene_expression of Cenpj 1 0.23 0.61 0.09 19.96
179 INT16153 Gene_expression of Cenpj 7 0.77 2.56 1.42 19.52
180 INT101482 Negative_regulation of Lep 53 0.54 33.59 5.65 16.44
181 INT167270 Negative_regulation of Gene_expression of Lep 13 0.55 5.48 1.19 16.44
182 INT101483 Gene_expression of Lep 159 0.78 104.77 25.12 16.16
183 INT20205 Binding of IgG 108 0.46 66.68 8.57 14.60
184 INT2673 Negative_regulation of PROC 93 0.57 50.34 12.79 13.92
185 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85 13.60
186 INT48593 Positive_regulation of NOS1 420 0.68 226.15 114.71 13.60
187 INT90909 Negative_regulation of Gene_expression of NOS1 44 0.55 23.83 12.47 13.60
188 INT207779 Localization of Ap3d1 1 0.11 3.16 0.14 13.28
189 INT89128 Binding of DSPP 7 0.32 2.24 0.98 5.28
190 INT242945 Localization of PDE5A 9 0.75 4.57 1.28 5.20
191 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
192 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 5.00
193 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 5.00
194 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 5.00
195 INT6481 Binding of TNF 624 0.48 510.2 214.82 5.00
196 INT2391 Negative_regulation of PTGS1 501 0.59 207.62 205.6 5.00
197 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 5.00
198 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 5.00
199 INT1273 Gene_expression of Avp 356 0.78 90.56 138.7 5.00
200 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 5.00
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