P:Restless leg syndrome

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pChart

Pain Term
Category Disorder
Synonyms Intermittent Claudication
Pain Specific Yes
Documents 3311
Hot Single Events 200
Hot Interactions 12

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Restless leg syndrome. They are ordered first by their pain relevance and then by number of times they were reported for Restless leg syndrome. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT92269 Binding of F13A1 and F2 1 0.00 0.44 0.17 98.28
2 INT195217 EGFL7 Negative_regulation of Gene_expression of IL6 1 0.06 1.14 0.83 97.40
3 INT188789 Binding of pad and Mthfr 1 0.06 4.6 0.31 97.36
4 INT144588 Binding of EEF1A2 and pad 1 0.36 1.34 0.24 97.00
5 INT165507 CRAT Negative_regulation of Gene_expression of CYBB 1 0.00 0.1 0.1 96.84
6 INT195220 Binding of CPB2 and IL6 1 0.04 0.5 0.49 95.08
7 INT117971 Cd8a Negative_regulation of Positive_regulation of Ephb1 1 0.02 0.98 0.79 94.48
8 INT195219 Binding of CPB2 and CSRP1 1 0.03 0.99 0.96 93.52
9 INT110373 CYP4A11 Positive_regulation of PPARG 1 0.00 0.94 0.26 88.60
10 INT99842 Edn1 Negative_regulation of Localization of Ren 1 0.24 0.43 0.32 85.88
11 INT99843 Edn3 Negative_regulation of Localization of Ren 1 0.25 0.42 0.31 85.88
12 INT110377 Binding of Ncoa1 and Pparg 1 0.02 0.26 0.08 84.76
13 INT182819 Binding of CD63 and PECAM1 1 0.00 1.63 0.61 78.20
14 INT182815 Binding of CD63 and ICAM1 1 0.00 1.63 0.61 78.20
15 INT175329 Binding of ICAM1 and ITGAL 14 0.18 10.06 2.81 77.76
16 INT170127 Binding of ITGAL and PECAM1 2 0.01 2.71 0.75 77.76
17 INT182814 Binding of ICAM1 and PECAM1 2 0.02 3.32 0.77 77.36
18 INT57268 SERPINE1 Positive_regulation of SERPINC1 1 0.07 0.94 0.07 71.36
19 INT133481 TNF Positive_regulation of Phosphorylation of PTEN 1 0.13 0.61 0.09 55.32
20 INT195218 Binding of CSRP1 and F13A1 1 0.04 0.25 0.05 50.00
21 INT195222 Binding of ALB and CSRP1 1 0.11 0.25 0.05 50.00
22 INT195221 Binding of CSRP1 and NAGLU 1 0.17 0.25 0.05 50.00
23 INT195216 Binding of CSRP1 and IL6 1 0.23 0.25 0.05 50.00
24 INT355671 Binding of Saa and Hdlcl1 1 0.00 0.79 0.11 48.80
25 INT56449 Aap Positive_regulation of Icam1 1 0.31 0.75 0.5 48.40
26 INT79521 Ptger1 Negative_regulation of Positive_regulation of Tbce 1 0.00 0.57 0.2 47.16
27 INT133482 CREB1 Positive_regulation of KCNMA1 1 0.01 0.43 0.03 43.00
28 INT133483 AKT1 Positive_regulation of KCNMA1 1 0.00 0.43 0.03 43.00
29 INT133489 CREB1 Positive_regulation of Csnk2b 1 0.08 0.42 0.03 42.04
30 INT133490 AKT1 Positive_regulation of Csnk2b 1 0.02 0.42 0.03 42.04
31 INT133491 CREB1 Positive_regulation of Phosphorylation of Csnk2b 1 0.08 0.42 0.03 42.04
32 INT191718 Binding of FLT1 and VEGFA 35 0.50 12.18 0.27 27.04
33 INT265848 Binding of HSD11B1 and Cand1 1 0.40 0.85 0 25.52
34 INT27932 Binding of CCK and NCOR2 1 0.01 0.91 1.47 25.00
35 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1 5.00
36 INT278292 Binding of CRP and ESR1 6 0.09 10.92 0.96 5.00
37 INT181619 ACE Positive_regulation of KNG1 1 0.33 0.97 0.58 5.00
38 INT182813 EEF1A2 Negative_regulation of ITGAL 1 0.10 1.53 0.51 5.00
39 INT319718 Binding of Crebbp and Creb1 1 0.10 1.68 0.48 5.00
40 INT355672 Il6 Negative_regulation of Transcription of TNF 1 0.05 0.98 0.46 5.00
41 INT241853 Binding of SLC40A1 and HAMP 3 0.41 5.35 0.43 5.00
42 INT319729 Binding of Rela and Crebbp 1 0.02 0.88 0.37 5.00
43 INT265826 Binding of ACE and SERPINE1 1 0.24 1.08 0.3 5.00
44 INT182817 EEF1A2 Positive_regulation of BMP2 1 0.26 1.62 0.28 5.00
45 INT265831 BGN Positive_regulation of ADCY1 1 0.01 0.41 0.27 5.00
46 INT265830 KNG1 Positive_regulation of Localization of BGN 1 0.02 0.33 0.27 5.00
47 INT348755 Plat Regulation of Gene_expression of Cldn5 1 0.10 0.45 0.25 5.00
48 INT239087 Binding of SST and Negative_regulation of Localization of GH1 1 0.19 0.36 0.24 5.00
49 INT226073 Binding of CRP and SHBG 2 0.10 2.14 0.24 5.00
50 INT296372 Binding of IDUA and ACD 1 0.03 2.72 0.23 5.00
51 INT265828 ACE Regulation of Gene_expression of KNG1 1 0.32 0.83 0.22 5.00
52 INT182816 EEF1A2 Negative_regulation of CRP 1 0.28 1.84 0.21 5.00
53 INT259934 Plat Positive_regulation of Gene_expression of Mmp9 2 0.33 1.05 0.17 5.00
54 INT348756 Gopc Positive_regulation of Gene_expression of Mmp9 1 0.10 0.77 0.17 5.00
55 INT265827 ACE Negative_regulation of ANGPT2 1 0.09 0.59 0.17 5.00
56 INT319703 Binding of Rela and Crebbp Positive_regulation of Binding of Rela 1 0.00 0.37 0.12 5.00
57 INT319726 Crebbp Positive_regulation of Binding of Rela 1 0.02 0.37 0.12 5.00
58 INT319731 Ep300 Positive_regulation of Binding of Rela 1 0.01 0.37 0.12 5.00
59 INT319727 Binding of Crebbp and Ep300 1 0.02 0.36 0.11 5.00
60 INT319728 Positive_regulation of Binding of Crebbp and Ep300 1 0.03 0.36 0.11 5.00
61 INT286683 Gopc Positive_regulation of MBD2 1 0.01 1.07 0.11 5.00
62 INT236040 VIP Negative_regulation of SLC9A3 1 0.10 0 0.1 5.00
63 INT265829 ACE Positive_regulation of Protein_catabolism of KNG1 1 0.33 0.73 0.09 5.00
64 INT236043 ADCYAP1 Positive_regulation of VIPR1 1 0.00 0 0.09 5.00
65 INT221878 Binding of Ltp and Ctrcts 1 0.00 1.94 0.07 5.00
66 INT265750 Binding of FLT1 and KDR 1 0.37 0.54 0.07 5.00
67 INT197727 Binding of RARA and Positive_regulation of PPARA 1 0.02 0.96 0.05 5.00
68 INT197741 Binding of Rdh5 and Positive_regulation of PPARA 1 0.27 0.95 0.05 5.00
69 INT258084 Binding of IL6 and Regulation of Gene_expression of INS 1 0.11 0.62 0.05 5.00
70 INT245219 Binding of C3AR1 and C5AR1 1 0.34 1.21 0.04 5.00
71 INT265735 VEGFA Positive_regulation of Binding of KLKB1 1 0.04 0.36 0.04 5.00
72 INT265771 NRP1 Positive_regulation of VEGFA 1 0.46 0 0.04 5.00
73 INT265764 NRP1 Positive_regulation of FLT1 1 0.45 0 0.04 5.00
74 INT173051 Binding of VEGFA and NRP1 16 0.44 1.29 0.04 5.00
75 INT265745 FLT1 Positive_regulation of Binding of KLKB1 1 0.04 0.36 0.04 5.00
76 INT265772 Binding of KDR and NRP1 1 0.29 0 0.04 5.00
77 INT245216 Binding of C3 and C3AR1 1 0.19 1.21 0.04 5.00
78 INT265749 Binding of FLT1 and NRP1 1 0.43 0 0.04 5.00
79 INT245218 Binding of C3 and C5AR1 2 0.29 2.94 0.04 5.00
80 INT348757 Plat Negative_regulation of Cldn5 1 0.16 0.3 0.03 5.00
81 INT278291 Binding of CRP and DBP 1 0.12 1.57 0.03 5.00
82 INT278289 Binding of DBP and ESR1 1 0.03 0.82 0.03 5.00
83 INT278294 Binding of ESR1 and SHBG 1 0.01 0.82 0.03 5.00
84 INT224305 Positive_regulation of Binding of KDR and VEGFA 2 0.45 0.36 0.03 5.00
85 INT278290 Binding of CRP and PADI4 1 0.11 1.2 0.03 5.00
86 INT265730 Binding of AR and VEGFA 1 0.09 0 0 5.00
87 INT324347 Binding of UMOD and Scr 1 0.20 2.23 0 5.00
88 INT265744 VEGFA Regulation of Localization of NRP1 1 0.25 0 0 5.00
89 INT265708 Binding of FLT1 and VEGFA Positive_regulation of AR 1 0.13 0 0 5.00
90 INT236042 Negative_regulation of SLC9A3 Negative_regulation of SLC36A1 1 0.08 0.06 0 5.00
91 INT265753 Binding of FLT1 and KL 1 0.18 0 0 5.00
92 INT265760 Binding of KLKB1 and VEGFA 1 0.04 0.14 0 5.00
93 INT324342 UMOD Positive_regulation of Scr 1 0.17 1.29 0 5.00
94 INT165509 CYBB Regulation of Gene_expression of NFKB1 1 0.02 0 0 5.00
95 INT278295 DBP Positive_regulation of SHBG 1 0.02 0.92 0 5.00
96 INT324312 Binding of GATM and UMOD 1 0.02 1.62 0 5.00
97 INT324306 Binding of GATM and STC1 1 0.02 1.61 0 5.00
98 INT265759 KL Positive_regulation of Binding of VEGFA 1 0.25 0.14 0 5.00
99 INT265768 FLT1 Regulation of Binding of VEGFA 1 0.41 0 0 5.00
100 INT278293 Binding of DBP and SHBG 2 0.02 1.34 0 5.00
101 INT265767 Positive_regulation of Binding of VEGFA and NRP1 1 0.46 0 0 5.00
102 INT265754 Binding of FLT1 and KLKB1 1 0.03 0.07 0 5.00
103 INT265729 FLT1 Positive_regulation of Binding of VEGFA 1 0.46 0.08 0 5.00
104 INT265763 VEGFA Regulation of Binding of FLT1 1 0.41 0 0 5.00
105 INT165506 HSPG2 Negative_regulation of Gene_expression of CYBB 1 0.03 0.06 0 5.00
106 INT265747 Binding of KLKB1 and KL 1 0.02 0 0 5.00
107 INT324346 Regulation of UMOD Positive_regulation of Scr 1 0.10 1.31 0 5.00
108 INT324343 SLC12A1 Regulation of Scr 1 0.00 0.25 0 5.00
109 INT348759 Plat Regulation of LDHA 1 0.04 0.23 0 5.00
110 INT265732 Positive_regulation of Binding of FLT1 and VEGFA 1 0.52 0 0 5.00
111 INT286682 Maob Positive_regulation of Positive_regulation of PLEK 1 0.51 0.89 0 5.00
112 INT240685 Binding of DIRAS3 and KCNQ4 1 0.18 0.95 0 5.00
113 INT197725 Negative_regulation of CETP Positive_regulation of Positive_regulation of HSD11B1 1 0.11 1.15 0 5.00
114 INT197726 Negative_regulation of CETP Positive_regulation of HSD11B1 1 0.11 0.76 0 5.00
115 INT165511 Binding of HSPG2 and NOSTRIN 1 0.02 0.07 0 5.00
116 INT265709 FLT1 Regulation of Binding of FLT1 and SRA1 1 0.00 0 0 5.00
117 INT324305 Binding of CST3 and UMOD 1 0.05 3.22 0 5.00
118 INT265752 NRP1 Negative_regulation of Gene_expression of FLT1 1 0.33 0 0 5.00
119 INT265743 Binding of VEGFA and GOPC 1 0.15 0 0 5.00
120 INT324313 Binding of STC1 and UMOD 1 0.29 3.22 0 5.00
121 INT324311 Binding of UMOD and SHROOM3 1 0.29 1.62 0 5.00
122 INT256400 GLP1R Positive_regulation of Localization of GCG 1 0.02 0.15 0 5.00
123 INT265758 GOPC Positive_regulation of Gene_expression of FLT1 1 0.14 0 0 5.00
124 INT165510 HSPG2 Negative_regulation of Gene_expression of NFKB1 1 0.01 0.06 0 5.00
125 INT265728 Positive_regulation of Binding of KLKB1 and VEGFA 1 0.04 0 0 5.00
126 INT236044 Negative_regulation of SLC9A3 Negative_regulation of Gene_expression of SLC36A1 1 0.08 0.12 0 5.00
127 INT265765 Binding of NRP1 and GOPC 1 0.13 0 0 5.00
128 INT245217 Binding of CREM and TFAM 1 0.00 1.44 0 5.00
129 INT265737 Binding of AR and NRP1 1 0.10 0 0 5.00
130 INT324310 Binding of STC1 and SHROOM3 1 0.24 1.61 0 5.00
131 INT265751 NRP1 Negative_regulation of Localization of FLT1 1 0.33 0 0 5.00
132 INT324344 Positive_regulation of UMOD Regulation of Scr 1 0.24 0.29 0 5.00
133 INT324340 Binding of SLC12A1 and Scr 1 0.00 1.42 0 5.00
134 INT182818 EEF1A2 Negative_regulation of STAR 1 0.01 1.48 0 5.00
135 INT324309 Binding of CST3 and GATM 1 0.00 1.6 0 5.00
136 INT324345 Binding of STC1 and Scr 1 0.10 0.22 0 5.00
137 INT265756 Positive_regulation of Binding of AR and NRP1 1 0.10 0 0 5.00
138 INT265761 Binding of FLT1 and SRA1 1 0.01 0 0 5.00
139 INT265770 Binding of KDR and GOPC 1 0.10 0 0 5.00
140 INT240684 Binding of NAT2 and DIRAS3 1 0.03 0.95 0 5.00
141 INT265766 GOPC Positive_regulation of Gene_expression of VEGFA 1 0.16 0 0 5.00
142 INT348758 Plat Positive_regulation of LDHA 1 0.04 0.42 0 5.00
143 INT165508 Binding of HSPG2 and VEGFA 1 0.01 0.07 0 5.00
144 INT265757 Regulation of Binding of VEGFA and NRP1 1 0.41 0 0 5.00
145 INT324341 UMOD Regulation of Scr 1 0.21 0.29 0 5.00
146 INT265710 Binding of KDR and VEGFA Positive_regulation of AR 1 0.11 0 0 5.00
147 INT265738 NRP1 Positive_regulation of KLKB1 1 0.03 0 0 5.00
148 INT265774 Binding of FLT1 and GOPC 1 0.12 0 0 5.00
149 INT265762 Binding of VEGFA and RAB11FIP1 1 0.02 0 0 5.00
150 INT265769 GOPC Positive_regulation of Gene_expression of KL 1 0.08 0 0 5.00
151 INT265741 Negative_regulation of Binding of FLT1 and NRP1 1 0.38 0 0 5.00
152 INT324308 Binding of CST3 and SHROOM3 1 0.04 1.6 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Restless leg syndrome. They are ordered first by their pain relevance and then by number of times they were reported in Restless leg syndrome. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT39712 Binding of pad 82 0.48 110.92 10.33 100.00
2 INT75742 Binding of RLS 86 0.42 95.27 19.04 100.00
3 INT83734 Negative_regulation of RLS 24 0.50 35.75 5.66 100.00
4 INT36642 Negative_regulation of Pde1a 4 0.43 0.89 2.15 100.00
5 INT54924 Gene_expression of RLS 67 0.62 83.2 14.25 100.00
6 INT160075 Localization of Cad 1 0.04 0.82 0.45 100.00
7 INT133823 Localization of pad 7 0.64 6.81 1.52 100.00
8 INT613 Gene_expression of Alb 268 0.78 149.84 42.78 100.00
9 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86 100.00
10 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 100.00
11 INT14619 Positive_regulation of Localization of NAGLU 18 0.62 7.73 3.94 99.92
12 INT1375 Negative_regulation of Pde4dl1 13 0.57 5.54 4.63 99.92
13 INT87517 Gene_expression of LDLR 73 0.69 37.35 3.32 99.88
14 INT7105 Gene_expression of pad 54 0.77 63.68 8.8 99.84
15 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84 99.84
16 INT3300 Positive_regulation of Gene_expression of Calca 179 0.70 77.76 144.2 99.84
17 INT37341 Regulation of Tyrp1 4 0.29 4.53 2.42 99.80
18 INT10976 Negative_regulation of ENPP3 13 0.42 5.11 1.92 99.78
19 INT119905 Negative_regulation of PDE3A 5 0.18 5 1.77 99.78
20 INT104634 Negative_regulation of Hsd3b3 6 0.35 1.79 6.49 99.68
21 INT49103 Positive_regulation of Vcam1 71 0.69 59.52 19.85 99.60
22 INT21938 Positive_regulation of Atp7b 26 0.10 11.33 7.1 99.60
23 INT86999 Regulation of DYNLL1 5 0.44 2.85 2.18 99.56
24 INT95207 Negative_regulation of Pde5a 46 0.58 32.01 10.14 99.52
25 INT195226 Positive_regulation of ACR 23 0.26 7.85 12.62 99.48
26 INT663 Negative_regulation of Adrb3 55 0.59 15.95 14.68 99.48
27 INT195228 Negative_regulation of Positive_regulation of ACR 1 0.10 0.82 0.49 99.48
28 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 99.38
29 INT24910 Negative_regulation of Enpp3 20 0.57 8.23 4.67 99.36
30 INT17086 Binding of HSD11B1 84 0.47 122.28 6.16 99.36
31 INT1631 Binding of Hdl1 42 0.36 49.22 2.92 99.36
32 INT109379 Regulation of Phosphorylation of Ephb1 22 0.59 12.58 18.84 99.30
33 INT1973 Positive_regulation of NAGLU 36 0.65 14.78 7 99.28
34 INT756 Gene_expression of C3 138 0.75 100.6 19.2 99.28
35 INT36142 Negative_regulation of Hmgcr 33 0.46 15.91 3.54 99.28
36 INT28891 Localization of Selp 13 0.60 8.23 2.83 99.28
37 INT28892 Positive_regulation of Localization of Selp 3 0.35 1.04 1.4 99.28
38 INT167601 Negative_regulation of Mbsyd 1 0.02 1.2 0.27 99.28
39 INT97846 Regulation of VEGFC 3 0.14 1.2 0.44 99.28
40 INT56792 Positive_regulation of Negative_regulation of F13A1 2 0.12 1.51 0.42 99.28
41 INT11679 Negative_regulation of F13A1 55 0.54 33.69 9.43 99.28
42 INT45613 Positive_regulation of pad 23 0.50 24.18 4.8 99.24
43 INT19847 Positive_regulation of Localization of Alb 21 0.70 13.89 4.16 99.24
44 INT3889 Regulation of Serpinc1 13 0.61 8.6 3.46 99.24
45 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 99.14
46 INT2271 Gene_expression of F2 51 0.76 30.21 7.97 99.12
47 INT4498 Gene_expression of F2 83 0.65 57.4 10.8 99.08
48 INT10585 Localization of NAGLU 53 0.80 23.32 12.75 99.08
49 INT63934 Phosphorylation of Ephb1 377 0.82 150.52 188.66 99.08
50 INT174273 Positive_regulation of Binding of F2 3 0.08 2.99 1.02 99.08
51 INT9842 Binding of F2 36 0.47 22.79 4.42 99.08
52 INT3466 Gene_expression of Ptger1 39 0.75 18.34 15.75 98.96
53 INT10139 Positive_regulation of F13A1 64 0.56 44.75 9.69 98.88
54 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 98.86
55 INT7678 Localization of Alb 142 0.81 80.93 22.49 98.84
56 INT51017 Positive_regulation of Icam1 113 0.70 81.16 35.55 98.84
57 INT17686 Negative_regulation of Hdl1 72 0.36 81.85 7.74 98.84
58 INT34585 Negative_regulation of Positive_regulation of HSD11B1 31 0.57 43.54 2.47 98.84
59 INT28871 Regulation of CSRP1 8 0.46 6.29 4.04 98.80
60 INT50050 Gene_expression of CSRP1 23 0.76 16.84 5.86 98.80
61 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 98.72
62 INT15684 Positive_regulation of Serpine1 65 0.70 43.51 13.67 98.64
63 INT15921 Positive_regulation of Serpine1 85 0.68 81.24 13.4 98.64
64 INT11071 Positive_regulation of PPBP 43 0.68 26.85 13.43 98.64
65 INT1734 Negative_regulation of HSD11B1 116 0.57 125.13 10.52 98.60
66 INT121471 Negative_regulation of Pde3a 24 0.34 13.79 4.73 98.60
67 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 98.52
68 INT22454 Regulation of Crp 213 0.62 160.67 49.24 98.48
69 INT10863 Positive_regulation of Ldlr 45 0.68 31.06 7.05 98.28
70 INT92264 Protein_catabolism of F2 2 0.03 0.98 0.23 98.28
71 INT28872 Positive_regulation of CSRP1 49 0.70 47.23 11.7 98.20
72 INT5166 Binding of Ldlr 14 0.48 11.95 3.32 98.20
73 INT2378 Negative_regulation of SERPINE1 47 0.59 34.55 9.9 98.12
74 INT10534 Positive_regulation of Trib3 209 0.60 78.75 81.48 98.12
75 INT119591 Gene_expression of Olfr589 1 0.00 0.73 0.36 98.00
76 INT8640 Positive_regulation of HSD11B1 332 0.67 377.84 22.36 97.98
77 INT26364 Positive_regulation of CS 12 0.30 4.99 1.89 97.96
78 INT63932 Positive_regulation of Ephb1 537 0.70 259.67 296.14 97.88
79 INT164634 Regulation of EGFL7 4 0.09 3.06 1.15 97.88
80 INT57549 Gene_expression of GNPTAB 49 0.65 57.5 9.05 97.84
81 INT234 Binding of Alb 151 0.48 52.34 32.97 97.80
82 INT55743 Gene_expression of Timp2 25 0.31 8.95 4.3 97.54
83 INT9650 Gene_expression of LPA 141 0.75 104.57 29 97.52
84 INT7475 Positive_regulation of Hdl1 138 0.67 175.81 15.05 97.44
85 INT164633 Gene_expression of EGFL7 23 0.53 10.46 3.1 97.40
86 INT195230 Negative_regulation of Gene_expression of EGFL7 4 0.08 2.83 1.59 97.40
87 INT99477 Negative_regulation of Enpp3 3 0.30 2.45 0.88 97.36
88 INT9899 Gene_expression of Vwf 91 0.74 45.06 9.13 97.28
89 INT73263 Negative_regulation of MYC 20 0.57 12.86 2.95 97.24
90 INT46201 Gene_expression of KLKB1 21 0.53 3.01 2.87 97.22
91 INT63880 Positive_regulation of FLNA 29 0.59 13.88 3.97 97.20
92 INT67613 Positive_regulation of PPARG 94 0.70 69.15 34.38 97.20
93 INT80329 Positive_regulation of THBD 12 0.47 20.96 2.45 97.12
94 INT11858 Localization of Tbxa2r 39 0.80 21.24 7.09 97.08
95 INT103154 Gene_expression of FLT1 138 0.76 58.5 7.41 97.08
96 INT130083 Positive_regulation of Positive_regulation of Vcam1 8 0.36 5.81 4.31 97.04
97 INT123839 Positive_regulation of Timp2 6 0.15 4.69 1.21 96.98
98 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59 96.96
99 INT98448 Regulation of Binding of Il6 3 0.39 2.6 1.46 96.96
100 INT51474 Binding of Il6 55 0.48 44.99 20.52 96.96
101 INT98449 Positive_regulation of Binding of Il6 3 0.44 2.96 1.44 96.96
102 INT95597 Gene_expression of HTC1 1 0.15 0.26 0.3 96.92
103 INT45563 Regulation of Rpia 3 0.59 2.11 0.99 96.88
104 INT74447 Gene_expression of Vwf 39 0.76 21.96 4.66 96.88
105 INT116433 Gene_expression of CYBB 93 0.70 50.44 11.91 96.84
106 INT16997 Binding of PRTN3 34 0.48 33.44 6.45 96.80
107 INT719 Negative_regulation of SGCG 96 0.57 47.91 30.22 96.76
108 INT17381 Gene_expression of Tbxa2r 146 0.78 65.01 34.15 96.70
109 INT9506 Transcription of Mb 4 0.47 2.08 0.39 96.68
110 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85 96.68
111 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71 96.68
112 INT27785 Regulation of HTR2A 11 0.44 8 8.18 96.60
113 INT52732 Negative_regulation of CRP 169 0.59 138.47 40.33 96.60
114 INT153300 Negative_regulation of Gene_expression of CRP 48 0.58 39.97 7.58 96.60
115 INT194074 Regulation of NAGLU 5 0.38 2.93 1.87 96.44
116 INT8785 Gene_expression of ALDH7A1 16 0.75 5.55 1.92 96.40
117 INT103124 Regulation of Cd8a 3 0.23 1.65 0.68 96.40
118 INT84388 Negative_regulation of PDE3B 16 0.57 11.25 2.18 96.36
119 INT24909 Negative_regulation of Pde10a 4 0.43 0.87 1.87 96.20
120 INT10893 Binding of VWF 27 0.47 25.02 2.82 96.20
121 INT10826 Binding of Bcl2a1b 2 0.03 1.39 0.31 96.20
122 INT83188 Binding of PAOD1 2 0.29 1.15 0.51 96.12
123 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 96.12
124 INT6624 Gene_expression of Pth 135 0.76 110.27 27.54 96.12
125 INT22083 Regulation of Pth 55 0.62 22.32 8.9 96.12
126 INT58566 Regulation of Gene_expression of Pth 5 0.58 2.3 0.38 96.12
127 INT10915 Gene_expression of ITGAM 164 0.78 92.42 29.78 96.08
128 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 96.08
129 INT253862 Binding of Aod1 1 0.03 1.51 0.1 96.08
130 INT71933 Positive_regulation of Gene_expression of F2 19 0.56 14.24 2.53 96.04
131 INT9210 Regulation of IL6 166 0.62 125.61 49.95 95.92
132 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15 95.84
133 INT110211 Negative_regulation of Gene_expression of CSRP1 3 0.43 2.16 1.25 95.84
134 INT163134 Gene_expression of ACR 78 0.65 30.39 38.48 95.76
135 INT899 Gene_expression of F13A1 122 0.70 78.02 16.26 95.76
136 INT83642 Gene_expression of CD63 22 0.77 10.06 2.63 95.76
137 INT3163 Gene_expression of NAGLU 28 0.75 15.23 4.98 95.76
138 INT7106 Regulation of pad 8 0.27 5.24 2.16 95.68
139 INT2129 Positive_regulation of F2 83 0.70 58.95 12.63 95.60
140 INT4047 Binding of F13A1 105 0.43 66.54 11.81 95.58
141 INT56651 Binding of HLA-DRB1 58 0.48 52.25 13.68 95.58
142 INT167602 Binding of Mbsyd 2 0.14 3 0.31 95.52
143 INT20121 Negative_regulation of CYBB 34 0.54 15.5 4.44 95.52
144 INT9649 Positive_regulation of LPA 105 0.69 74.75 13.89 95.48
145 INT93738 Gene_expression of Tnfrsf1a 63 0.74 57.66 23.09 95.36
146 INT49105 Gene_expression of Vcam1 157 0.78 157.27 43.01 95.36
147 INT87193 Gene_expression of Tnfrsf1b 30 0.58 29.4 9.22 95.36
148 INT1888 Protein_catabolism of F13A1 97 0.99 63.48 14.82 95.32
149 INT11342 Positive_regulation of PAOD1 3 0.38 2.28 0.33 95.32
150 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 95.28
151 INT19966 Positive_regulation of C9orf3 19 0.67 21.88 4.38 95.28
152 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 95.28
153 INT56652 Protein_catabolism of HLA-DRB1 1 0.00 1.77 0.19 95.18
154 INT198851 Gene_expression of MARK3 3 0.65 2.55 0.28 95.16
155 INT49142 Gene_expression of SELP 94 0.75 54.61 11.64 95.04
156 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 94.88
157 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 94.84
158 INT3757 Positive_regulation of Gene_expression of ALB 45 0.69 23.73 6.85 94.84
159 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 94.80
160 INT118606 Protein_catabolism of CXCL10 2 0.86 0.98 1.22 94.72
161 INT170180 Protein_catabolism of Vwf 1 0.64 0.85 0.14 94.72
162 INT60436 Negative_regulation of COPD 76 0.37 84.22 9.08 94.64
163 INT72948 Localization of Ppbp 1 0.01 1.19 0.19 94.60
164 INT3366 Localization of PLEK 44 0.78 15.83 9.55 94.60
165 INT41358 Localization of Pf4 11 0.79 6.06 2.89 94.60
166 INT36809 Positive_regulation of Rpia 1 0.46 0.44 0.19 94.56
167 INT63933 Negative_regulation of Positive_regulation of Ephb1 53 0.58 22.83 33.43 94.48
168 INT50031 Negative_regulation of Gene_expression of CYP2B6 5 0.57 2.37 1.29 94.48
169 INT18772 Positive_regulation of Gene_expression of CYP2B6 14 0.49 2.93 5.4 94.48
170 INT10796 Gene_expression of CYP2B6 131 0.77 30.14 35.27 94.48
171 INT49141 Gene_expression of Selp 157 0.78 85.22 24.78 94.40
172 INT188788 Negative_regulation of Gene_expression of Mthfr 2 0.33 1.3 0.39 94.24
173 INT212160 Negative_regulation of Positive_regulation of pad 1 0.16 0.48 0.09 94.08
174 INT158796 Positive_regulation of SMUG1 67 0.70 38.97 8.98 94.04
175 INT51803 Negative_regulation of Pde7a 14 0.59 14.98 4.85 94.00
176 INT88667 Negative_regulation of Gene_expression of F2 11 0.41 5.53 1.62 93.92
177 INT17501 Negative_regulation of F2 70 0.58 32.23 7.51 93.92
178 INT124417 Gene_expression of Mthfr 8 0.60 8.65 2.53 93.80
179 INT3971 Positive_regulation of Alb 175 0.70 98.46 36.45 93.52
180 INT45721 Transcription of Plg 1 0.20 0.16 0.18 93.44
181 INT2774 Binding of Crp 241 0.48 195.89 44.39 93.36
182 INT57728 Regulation of LDLR 25 0.41 13.18 3.46 93.28
183 INT63936 Positive_regulation of Phosphorylation of Ephb1 131 0.70 49.38 73.16 93.24
184 INT5114 Gene_expression of Ptgis 41 0.50 21.43 8.1 93.24
185 INT15917 Positive_regulation of Gene_expression of Ptgis 5 0.35 3.69 0.95 93.24
186 INT64247 Regulation of Phdlc1 2 0.03 2.21 0.66 93.08
187 INT28486 Positive_regulation of Phdlc1 18 0.40 14.4 2.17 92.96
188 INT16644 Positive_regulation of Plg 16 0.60 6.38 3.62 92.88
189 INT15920 Regulation of Serpine1 34 0.42 17.36 4.89 92.76
190 INT43985 Regulation of LPA 29 0.62 20.79 3.29 92.76
191 INT3952 Negative_regulation of ALB 116 0.59 72.18 18.35 92.76
192 INT8637 Negative_regulation of Dbp 112 0.50 33.28 8.4 92.76
193 INT30314 Negative_regulation of Ptgir 3 0.34 1.08 0.76 92.64
194 INT45612 Negative_regulation of pad 8 0.37 6.74 2.57 92.48
195 INT110210 Negative_regulation of CSRP1 12 0.59 8.96 2.81 92.44
196 INT86062 Positive_regulation of Tnfrsf1a 51 0.69 40.69 26.2 92.32
197 INT8579 Gene_expression of Apoa1 13 0.76 35.89 7.21 92.20
198 INT39948 Binding of FLNA 45 0.42 58.05 4.27 91.72
199 INT61946 Positive_regulation of HGF 57 0.69 38.93 11.99 91.64
200 INT10918 Gene_expression of ITGB2 93 0.76 71.8 16.34 91.36
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