P:Shingles

From wiki-pain
Jump to: navigation, search

pChart

Pain Term
Category Disorder
Synonyms None
Pain Specific No
Documents 256
Hot Single Events 14
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Shingles. They are ordered first by their pain relevance and then by number of times they were reported for Shingles. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT347165 Binding of NOTCH1 and PAX5 1 0.05 0.86 0.03 5.00
2 INT347163 NOTCH1 Positive_regulation of MSC 1 0.03 0.85 0.03 5.00
3 INT347164 NOTCH1 Negative_regulation of Gene_expression of EBF1 1 0.03 0.85 0.03 5.00
4 INT347162 MDM2 Negative_regulation of TP53 1 0.02 1.09 0 5.00
5 INT256502 Sis Regulation of Tg(CAG-EGFP)D4Nagy 1 0.00 0.1 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Shingles. They are ordered first by their pain relevance and then by number of times they were reported in Shingles. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT70933 Regulation of SEPHS1 3 0.37 2.56 0.81 98.60
2 INT31949 Negative_regulation of PIF1 5 0.05 4 1.38 98.44
3 INT95 Positive_regulation of Adrb1 34 0.62 11.95 14.41 93.68
4 INT7531 Positive_regulation of Eef1a1 29 0.62 8.16 15.41 93.24
5 INT142597 Regulation of Binding of Apoe 1 0.34 2.21 0.8 92.56
6 INT72141 Binding of Apoe 11 0.37 10.91 3.27 91.52
7 INT69029 Gene_expression of PTPRC 127 0.75 74.26 11.57 88.24
8 INT66585 Gene_expression of IER3 13 0.63 7.39 3.48 88.24
9 INT94876 Gene_expression of LY6G6E 1 0.01 1.82 0.48 88.24
10 INT67589 Gene_expression of MT1E 8 0.51 7.52 1.09 87.08
11 INT55224 Gene_expression of DRGX 99 0.31 67.55 67.63 83.92
12 INT278362 Negative_regulation of Hps5 2 0.21 15.71 4.44 82.48
13 INT51946 Gene_expression of Apold1 13 0.39 3.56 6.08 81.16
14 INT8634 Gene_expression of Nfasc 23 0.68 9.16 14.96 80.12
15 INT8380 Positive_regulation of Gene_expression of Npy 49 0.70 19.62 24.13 75.48
16 INT130793 Positive_regulation of Gene_expression of Nfasc 1 0.02 1.76 0.99 75.48
17 INT6108 Gene_expression of Npy 292 0.78 110.65 148.21 75.08
18 INT169076 Localization of MRVI1 1 0.68 1.94 0.35 74.80
19 INT2120 Gene_expression of CD79A 159 0.78 111.69 17.16 73.40
20 INT107575 Positive_regulation of Gene_expression of Atf3 25 0.69 27.37 14.55 71.32
21 INT107576 Gene_expression of Atf3 114 0.78 72.42 38.64 70.92
22 INT48248 Gene_expression of Scn10a 38 0.78 19.3 25.05 70.92
23 INT35368 Positive_regulation of Tk1 9 0.53 4.68 1.81 62.16
24 INT81102 Positive_regulation of Positive_regulation of Tk1 2 0.35 1.45 0.61 62.16
25 INT11325 Gene_expression of HLA-E 209 0.76 98.05 33.72 61.40
26 INT81103 Phosphorylation of Tk1 4 0.40 3.07 0.87 60.20
27 INT81099 Positive_regulation of Pol1 1 0.09 1.29 0.13 54.52
28 INT5328 Positive_regulation of CD4 191 0.69 133.43 21.31 50.00
29 INT5870 Negative_regulation of IFNA2 20 0.49 12 4.3 50.00
30 INT11235 Positive_regulation of IFNA2 27 0.69 15.32 2.57 50.00
31 INT114017 Gene_expression of CD200 10 0.75 2.38 0.88 50.00
32 INT92349 Positive_regulation of MAX 3 0.41 1.46 0.53 50.00
33 INT232187 Gene_expression of DFNB31 1 0.06 1.32 0.29 50.00
34 INT56816 Gene_expression of Tk1 7 0.59 4.92 0.9 49.28
35 INT18357 Gene_expression of TRPV1 825 0.78 307.11 382.81 48.96
36 INT67590 Gene_expression of RDBP 9 0.51 5.17 1.1 46.68
37 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 46.24
38 INT285834 Gene_expression of ORF63 1 0.02 4.52 0 44.24
39 INT148271 Regulation of SGCA 10 0.37 5.89 0.86 43.20
40 INT9382 Regulation of TRPV1 149 0.62 53.99 77.46 41.64
41 INT9383 Localization of TRPV1 98 0.81 33.23 46.24 41.64
42 INT278318 Gene_expression of Hps5 10 0.37 4.24 1.27 41.24
43 INT15514 Negative_regulation of Crp 275 0.59 194.6 64.86 40.80
44 INT49436 Binding of TRPV1 145 0.48 38.35 55.08 38.44
45 INT81100 Binding of Pol1 1 0.08 0.71 0.03 31.92
46 INT116426 Gene_expression of Pdpn 7 0.58 2.75 0.29 28.24
47 INT81101 Regulation of Phosphorylation of Tk1 1 0.02 0.77 0.07 25.00
48 INT55655 Gene_expression of DCN 17 0.75 7.98 5.98 19.40
49 INT48896 Positive_regulation of Gene_expression of Il10 73 0.70 43.14 35.5 7.20
50 INT48895 Gene_expression of Il10 333 0.78 221.2 138.52 6.80
51 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02 5.00
52 INT796 Gene_expression of Penk 1902 0.78 275.47 1057.59 5.00
53 INT5202 Positive_regulation of Gene_expression of Fos 1163 0.70 319.28 684 5.00
54 INT292 Localization of Penk 876 0.81 88.44 669.14 5.00
55 INT728 Positive_regulation of Penk 1068 0.70 186.9 636.87 5.00
56 INT5228 Positive_regulation of Fos 934 0.70 209.8 503.87 5.00
57 INT1395 Negative_regulation of Penk 537 0.59 87.33 389.81 5.00
58 INT6056 Negative_regulation of Gene_expression of Fos 601 0.59 193.05 386.84 5.00
59 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85 5.00
60 INT5680 Gene_expression of Ngf 530 0.78 264.29 310.56 5.00
61 INT5591 Regulation of Gene_expression of Fos 425 0.62 129.06 265.78 5.00
62 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 5.00
63 INT798 Positive_regulation of Gene_expression of Penk 394 0.70 78.53 203.07 5.00
64 INT2780 Regulation of Gene_expression of Penk 265 0.62 32.45 143.88 5.00
65 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 5.00
66 INT85640 Gene_expression of Tg(CAG-EGFP)D4Nagy 1138 0.72 311.58 119.18 5.00
67 INT170025 Gene_expression of Fig4 588 0.67 183.27 113.32 5.00
68 INT293 Protein_catabolism of Penk 161 1.00 11.71 98.45 5.00
69 INT214 Localization of AVP 370 0.81 208.51 91.09 5.00
70 INT16254 Positive_regulation of Gene_expression of Ngf 144 0.70 80.61 82.08 5.00
71 INT5590 Negative_regulation of Fos 144 0.59 40.94 81.98 5.00
72 INT171145 Positive_regulation of Fig4 274 0.59 93.55 69.81 5.00
73 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 5.00
74 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 5.00
75 INT88322 Gene_expression of CCR5 111 0.78 77.36 39.84 5.00
76 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 5.00
77 INT52690 Positive_regulation of Ptgs2 65 0.68 39.51 30.02 5.00
78 INT22211 Positive_regulation of CYP3A4 110 0.70 22 28.27 5.00
79 INT12129 Gene_expression of CYP3A4 107 0.78 23.11 27.6 5.00
80 INT19856 Gene_expression of CD8A 240 0.75 147.86 26.39 5.00
81 INT52457 Gene_expression of ABCB1 129 0.78 38.68 19.88 5.00
82 INT18311 Positive_regulation of CD8A 145 0.69 113.48 19.44 5.00
83 INT89594 Gene_expression of Ccl5 44 0.54 24.08 18.62 5.00
84 INT80755 Gene_expression of CD40 88 0.75 53.68 17.86 5.00
85 INT89293 Positive_regulation of Gene_expression of CCR5 29 0.70 22.14 15 5.00
86 INT1125 Positive_regulation of IGHG3 130 0.69 112.07 13.18 5.00
87 INT10870 Regulation of IgG 67 0.59 43.27 12.74 5.00
88 INT102731 Regulation of ABCB1 29 0.62 5.36 11.67 5.00
89 INT52688 Transcription of Ptgs2 16 0.69 8.31 7.52 5.00
90 INT1664 Gene_expression of Kitl 30 0.65 13.63 7.47 5.00
91 INT89589 Negative_regulation of Ccl5 9 0.40 4.62 7.39 5.00
92 INT91758 Binding of CCR5 28 0.45 20.16 7.07 5.00
93 INT28122 Gene_expression of MSC 111 0.58 26.83 6.57 5.00
94 INT85923 Positive_regulation of CREM 25 0.67 7.03 6.53 5.00
95 INT13352 Regulation of Kitl 11 0.45 3.91 6.07 5.00
96 INT22128 Positive_regulation of HIVEP1 61 0.43 70.52 6.07 5.00
97 INT117189 Binding of CXCR4 34 0.37 24.27 5.81 5.00
98 INT43524 Positive_regulation of Sh2b2 16 0.58 2.95 5.78 5.00
99 INT106667 Gene_expression of NDRG1 18 0.70 9.96 5.14 5.00
100 INT95131 Binding of Cd4 27 0.37 21.62 5.07 5.00
101 INT60252 Binding of HIVEP1 59 0.32 65.12 5.06 5.00
102 INT71418 Binding of CES1 42 0.40 29.78 5.01 5.00
103 INT26583 Positive_regulation of Cd4 40 0.54 21.96 4.83 5.00
104 INT89590 Negative_regulation of Gene_expression of Ccl5 8 0.36 3.97 4.67 5.00
105 INT88571 Positive_regulation of Tcas1 4 0.34 2.08 4.42 5.00
106 INT68369 Transcription of TNC 13 0.72 8.69 4.42 5.00
107 INT92509 Regulation of Sh2b2 7 0.35 3.41 3.8 5.00
108 INT122448 Regulation of Gene_expression of ABCB1 13 0.62 3.67 3.5 5.00
109 INT19491 Gene_expression of CD19 44 0.75 28.8 3.47 5.00
110 INT79270 Gene_expression of MKI67 113 0.77 63.52 3.38 5.00
111 INT48292 Negative_regulation of Sh2b2 9 0.26 2.14 3.26 5.00
112 INT181804 Negative_regulation of Gene_expression of Tg(CAG-EGFP)D4Nagy 57 0.50 12.54 3 5.00
113 INT106781 Negative_regulation of Ylpm1 5 0.49 5.36 2.95 5.00
114 INT110233 Regulation of Gene_expression of CCR5 6 0.34 7.14 2.76 5.00
115 INT182893 Gene_expression of Sh2b2 8 0.65 1.74 2.65 5.00
116 INT106668 Positive_regulation of Gene_expression of NDRG1 3 0.10 1.93 2.49 5.00
117 INT106616 Gene_expression of PSMB9 35 0.72 28.4 2.29 5.00
118 INT57501 Binding of CREM 11 0.27 3.67 2.15 5.00
119 INT161382 Localization of KRT20 25 0.61 12.97 2.13 5.00
120 INT95904 Gene_expression of CD27 45 0.76 26.17 1.93 5.00
121 INT42277 Gene_expression of GIPC1 6 0.25 2.06 1.61 5.00
122 INT114490 Gene_expression of PDLIM7 17 0.78 11.35 1.42 5.00
123 INT11203 Gene_expression of BCR 30 0.75 33.49 1.22 5.00
124 INT11063 Negative_regulation of CES1 16 0.53 6.92 1.11 5.00
125 INT132177 Binding of CD27 3 0.19 1.84 1 5.00
126 INT58692 Regulation of Gene_expression of CD8A 11 0.42 10.16 1 5.00
127 INT288676 Negative_regulation of CREM 3 0.18 1.34 0.96 5.00
128 INT347182 Negative_regulation of TNFAIP3 3 0.23 5.6 0.84 5.00
129 INT284739 Positive_regulation of Gene_expression of Sh2b2 2 0.26 0.83 0.71 5.00
130 INT158295 Transcription of CD8A 11 0.53 4.02 0.7 5.00
131 INT339019 Negative_regulation of Gm4010 1 0.01 0.78 0.64 5.00
132 INT278341 Positive_regulation of Hps5 8 0.38 5.47 0.62 5.00
133 INT3501 Localization of Sh2b2 6 0.73 0.88 0.62 5.00
134 INT136927 Gene_expression of HGS 18 0.70 14.42 0.6 5.00
135 INT74631 Gene_expression of UBXN11 19 0.75 6.11 0.57 5.00
136 INT148107 Binding of CDIPT 8 0.17 4.56 0.53 5.00
137 INT173801 Gene_expression of Ik 11 0.36 1.31 0.51 5.00
138 INT142972 Gene_expression of ID2 6 0.54 5.92 0.49 5.00
139 INT158426 Binding of NOTCH1 10 0.36 7.95 0.45 5.00
140 INT96584 Gene_expression of Gpm6b 3 0.15 1.89 0.42 5.00
141 INT328985 Negative_regulation of Negative_regulation of Hps5 1 0.03 1.07 0.39 5.00
142 INT278328 Negative_regulation of Gene_expression of Hps5 1 0.20 1.1 0.39 5.00
143 INT278331 Localization of Hps5 3 0.34 4.14 0.34 5.00
144 INT157135 Positive_regulation of MKI67 10 0.60 7.51 0.28 5.00
145 INT284738 Positive_regulation of Localization of Sh2b2 1 0.09 0.6 0.26 5.00
146 INT284733 Negative_regulation of Psmd5 1 0.02 1.31 0.23 5.00
147 INT252723 Gene_expression of SYK 3 0.25 2.67 0.23 5.00
148 INT88734 Regulation of CREM 10 0.27 2.01 0.21 5.00
149 INT214569 Positive_regulation of Localization of CD27 3 0.49 2.16 0.19 5.00
150 INT163189 Localization of CD27 7 0.74 5.31 0.18 5.00
151 INT88053 Gene_expression of IGHD@ 2 0.61 4.41 0.17 5.00
152 INT145856 Positive_regulation of GZMB 3 0.10 2.64 0.15 5.00
153 INT212170 Localization of CDIPT 4 0.41 1.55 0.13 5.00
154 INT186837 Gene_expression of EBNA1BP2 9 0.64 8.66 0.13 5.00
155 INT210578 Gene_expression of PAX5 5 0.44 3.46 0.12 5.00
156 INT146533 Gene_expression of EBF1 3 0.60 2 0.11 5.00
157 INT85983 Gene_expression of ELSPBP1 3 0.29 1.32 0.08 5.00
158 INT281221 Transcription of ORF61 2 0.05 1.51 0.06 5.00
159 INT347180 Gene_expression of TCF3 1 0.16 0.76 0.03 5.00
160 INT347178 Negative_regulation of Gene_expression of TCF3 1 0.09 0.77 0.03 5.00
161 INT266166 Negative_regulation of RPA1 2 0.08 1.65 0.03 5.00
162 INT347179 Negative_regulation of Gene_expression of EBF1 1 0.16 0.77 0.03 5.00
163 INT318764 Regulation of CTTNBP2 1 0.03 0.78 0 5.00
164 INT318743 Regulation of Transcription of ORF61 1 0.03 0.78 0 5.00
165 INT256492 Regulation of Gpm6b 1 0.02 0.59 0 5.00
166 INT347183 Positive_regulation of Gene_expression of CHRDL1 1 0.07 1.56 0 5.00
167 INT318766 Transcription of CTTNBP2 1 0.07 0.78 0 5.00
168 INT347181 Gene_expression of CHRDL1 1 0.09 1.56 0 5.00
169 INT214563 Positive_regulation of Localization of IGHD@ 2 0.06 1.38 0 5.00
170 INT347185 Gene_expression of MYBL1 1 0.12 0.9 0 5.00
171 INT318765 Regulation of Transcription of CTTNBP2 1 0.04 0.78 0 5.00
172 INT256491 Positive_regulation of Gpm6b 1 0.03 0.5 0 5.00
173 INT9696 Regulation of Ylpm1 1 0.38 0.08 0 5.00
174 INT285838 Positive_regulation of Binding of CD27 1 0.25 0.56 0 5.00
175 INT208149 Regulation of Positive_regulation of Cd4 1 0.06 0.93 0 5.00
176 INT214558 Localization of IGHD@ 2 0.10 2.89 0 5.00
177 INT285836 Binding of ORF61 1 0.36 1.85 0 5.00
178 INT285839 Gene_expression of C12orf61 1 0.01 1.45 0 5.00
179 INT328986 Transcription of Hps5 1 0.04 1.82 0 5.00
180 INT214564 Binding of IGHD@ 2 0.05 1.06 0 5.00
181 INT144114 Positive_regulation of Regulation of Ylpm1 1 0.42 0 0 5.00
182 INT285835 Localization of ORF63 1 0.02 1.39 0 5.00
183 INT256493 Gene_expression of Igkv4-62 1 0.26 0.66 0 5.00
184 INT318767 Gene_expression of WDR19 1 0.05 0.68 0 5.00
185 INT285840 Positive_regulation of Binding of IGHD@ 1 0.04 0.56 0 5.00
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox